CN210119389U - Medical heat-sensitive embedding mould - Google Patents
Medical heat-sensitive embedding mould Download PDFInfo
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- CN210119389U CN210119389U CN201920900436.4U CN201920900436U CN210119389U CN 210119389 U CN210119389 U CN 210119389U CN 201920900436 U CN201920900436 U CN 201920900436U CN 210119389 U CN210119389 U CN 210119389U
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Abstract
The utility model relates to the technical field of medical instruments, in particular to a medical thermosensitive embedding mold, which comprises a mold body, a first reversible thermosensitive coating and a second reversible thermosensitive coating; the mold body comprises a bottom wall and a plurality of side walls; the side walls are vertically arranged around the bottom wall, and the side walls and the bottom wall jointly enclose a cavity with an opening at one end; the first reversible thermosensitive coating is arranged on the inner side surface of the side wall; the second reversible thermosensitive coating is arranged on the top surface of the side wall; the color change temperature of the first reversible thermosensitive coating is lower than the color change temperature of the second thermosensitive coating. The utility model discloses a reversible temperature sensing coating of coating on embedding mould, the temperature range of the place of embedding mould can be directly perceived to indicate when the embedding, can regard as whether choose this mould for use for the reference of follow-up work, is favorable to improving the preparation quality of tissue slice sample, and is favorable to the automatic instrument development in later stage, reaches and reduces artificial purpose.
Description
Technical Field
The utility model relates to the technical field of medical apparatus, concretely relates to medical heat-sensitive embedding mould.
Background
In general, biopsy procedures involve: (1) tissue treatment process: placing the tissue for examination in an embedding box, fixing the tissue by using formalin fixing liquid to keep substances in tissue cells in an original state as much as possible, dehydrating by using gradient ethanol, transparentizing by using xylene, and dipping wax by using molten paraffin according to the principles of similar compatibility and osmosis of the substances, and finally replacing the liquid in the tissue cells by using paraffin; (2) embedding process: placing the processed tissue in an embedding mold, then placing an embedding box on the embedding mold, and injecting a proper amount of molten paraffin solution into the embedding mold through the embedding box so as to fill the embedding mold, solidify and cast the tissue and the embedding box together into a paraffin tissue embedding block, thereby facilitating subsequent tissue slicing; (3) slicing process: fixing the paraffin tissue embedded block which is completely solidified to a paraffin slicer so as to slice the paraffin tissue embedded block into a paraffin tissue slice with a preset thickness and attach the paraffin tissue slice to a glass slide; (4) and (3) dyeing process: dissolving paraffin and hydrated tissue slices on the glass slide, dyeing the tissue slices, performing gradient ethanol dehydration, and sealing the tissue slices by xylene transparent neutral gum; (4) microscopic examination process: wherein the stained tissue slices are observed under an optical microscope and corresponding results are given.
Because the embedding process is manually carried out, most of the embedding molds have a certain temperature difference between the metal product and the paraffin solution which is melted at high temperature (about 65 ℃ or higher), when the embedding molds have a large temperature difference between the metal product and the paraffin solution which is melted at high temperature (about 65 ℃ or higher), an obvious solidification layer appears in about less than 1 second after the paraffin solution is injected into the embedding molds, tissues are not yet placed in the embedding molds, at the moment, the embedding molds filled with partial paraffin and the tissues are required to be moved to a high-temperature heat source (about 65 ℃ or higher), the bottoms of the embedding molds are heated to pass through the metal heat conduction molten paraffin solidified layer, the proper positions of the tissues in the embedding molds are adjusted, so that the tissues are positioned and directionally attached to the bottom surfaces of the embedding molds, and then the embedding molds filled with the paraffin and the tissues are moved to a cooling device to accelerate paraffin solidification, the relative position of the tissue in the paraffin layer is fixed, so that the time consumption in unit time is long and the operation is troublesome; when the embedding mold is preheated by heating, the temperature difference between the paraffin solution melted at high temperature (about 65 ℃ or higher) can be reduced, but the degree of heating and warming of the embedding mold cannot be directly predicted; if the embedding mould is excessively heated and the temperature is too high, an operator is easy to be damaged by high temperature when using the embedding mould. In addition, if the temperature difference between the preheated embedding mold and the paraffin solution melted at a high temperature (about 65 ℃ or higher) is too small, not only the time for the paraffin to solidify is prolonged, but also the paraffin solution overflows to the outer surface of the embedding box. Thus, conventional embedding assemblies for biopsy are not directly usable for subsequent sectioning procedures, i.e., the process of sectioning paraffin-embedded tissue blocks, requiring additional operations to remove the solidified paraffin from the side surfaces of the embedding cassette.
Typically, paraffin wax having a melting point in the range of about 58 ℃ to 60 ℃ is used for embedding, and the temperature of the molten paraffin wax is 5 ℃ to 7 ℃ higher than the melting point of the paraffin wax used in order to ensure that all sides of the tissue sample are surrounded by the molten paraffin wax solution. For example, if paraffin with a melting point of 58 ℃ is used for embedding, the temperature of the molten paraffin should be adjusted to 63-65 ℃. Research shows that the temperature of human skin is between 20 and 47 ℃, and when the temperature is about 35 ℃, the human skin generates temperature sense; when the temperature exceeds 45 ℃, a hot or even scaly feeling is generated; when the temperature reaches 47 ℃, scald pain is caused; when the temperature is higher than 50 ℃, the burn is caused to form blisters; if the skin of a human body is contacted for one minute at 60 ℃, III-degree scalds can be caused.
The invention patent publication No. CN104870976A discloses an embedding cassette for biopsy, and the embedding cassette is for forming a space capable of accommodating tissue therein in an embedding mold when the embedding cassette is coupled to the embedding mold, and for embedding the tissue accommodated in the embedding mold in a state where the embedding cassette is coupled to the embedding mold, the embedding cassette including: a main body having a space connected to the receiving space of the coupled embedding mold, and in which the injected paraffin solution can be solidified when the embedding work is performed; and at least one paraffin partition groove formed on an edge of a lower surface of the main body, wherein when an embedding work is performed by being coupled to an embedding mold, the injected paraffin solution forms a partition by flowing into the at least one paraffin partition groove, thereby preventing the paraffin solution from flowing out through the embedding mold. The invention only plays a role in preventing paraffin solution from overflowing and has no design for preventing operators from being scalded.
SUMMERY OF THE UTILITY MODEL
The utility model discloses the technical problem that will solve is: provides a medical thermosensitive embedding mould which can intuitively predict the operating temperature range and prevent high-temperature damage.
In order to solve the technical problem, the utility model discloses a technical scheme be: a medical thermosensitive embedding mold comprises a mold body, a first reversible thermosensitive coating and a second reversible thermosensitive coating;
the mold body comprises a bottom wall and a plurality of side walls;
the side walls are vertically arranged around the bottom wall, and the side walls and the bottom wall jointly enclose a cavity with an opening at one end;
the first reversible thermosensitive coating is arranged on the inner side surface of the side wall, and the color of the first reversible thermosensitive coating is changed when the temperature of the first reversible thermosensitive coating reaches the color-changing temperature;
the second reversible thermosensitive coating is arranged on the top surface of the side wall, and the color of the second reversible thermosensitive coating changes when the temperature of the second reversible thermosensitive coating reaches the color-changing temperature;
the color change temperature of the first reversible thermosensitive coating is lower than the color change temperature of the second thermosensitive coating.
Wherein the first reversible thermosensitive coating is a silver tetraiodomercuric acid coating.
Wherein the second reversible thermosensitive coating is a copper tetraiodomercuric acid coating.
Wherein a draft angle with a vertical projection of 0-2 degrees is arranged between the side wall and the bottom wall.
The outer edge of the top surface of the side wall is provided with a protection groove, the protection groove is made into an arc shape, and the surface of the protection groove is provided with anti-skidding salient points.
Wherein, the protection groove is made of high-temperature-resistant silica gel material.
The beneficial effects of the utility model reside in that: the utility model discloses a reversible temperature sensing coating of coating on embedding mould, the temperature range of the place of embedding mould can be directly perceived to indicate when the embedding, can regard as whether choose this mould for use for the reference of follow-up work, is favorable to improving the preparation quality of tissue slice sample, and is favorable to the automatic instrument development in later stage, reaches and reduces artificial purpose.
Drawings
Fig. 1 is a schematic structural view of a medical heat-sensitive embedding mold according to an embodiment of the present invention;
fig. 2 is a front view of a medical heat-sensitive embedding mold according to an embodiment of the present invention;
fig. 3 is a side view of a medical heat-sensitive embedding mold according to an embodiment of the present invention;
description of reference numerals:
1. a mold body; 11. a bottom wall; 12. a side wall; 121. a protection groove;
2. a first reversible thermosensitive coating;
3. a second reversible thermosensitive coating.
Detailed Description
In order to explain the technical content, the objects and the effects of the present invention in detail, the following description is made with reference to the accompanying drawings in combination with the embodiments.
The utility model discloses the most crucial design lies in: the utility model discloses a reversible temperature sensing coating of coating on the embedding mould, the temperature range of the place of embedding mould can be indicateed directly perceivedly when the embedding.
Referring to fig. 1, fig. 2 and fig. 3, the medical thermosensitive embedding mold provided by the present invention includes a mold body 1, a first reversible thermosensitive coating 2 and a second reversible thermosensitive coating 3;
the mould body 1 comprises a bottom wall 11 and a plurality of side walls 12;
the side walls 12 are vertically arranged around the bottom wall 11, and the side walls 12 and the bottom wall 11 jointly enclose a cavity with an opening at one end;
the first reversible thermosensitive coating 2 is arranged on the inner side surface of the side wall 12, and the color of the first reversible thermosensitive coating 2 is changed when the temperature reaches the color-changing temperature;
the second reversible thermosensitive coating 3 is arranged on the top surface of the side wall 12, and the color of the second reversible thermosensitive coating 3 changes when the temperature reaches the color-changing temperature;
the color change temperature of the first reversible thermosensitive coating 2 is lower than that of the second thermosensitive coating.
The working principle of the medical thermosensitive embedding mold is as follows: when the embedding mold is used, when the temperature of the embedding mold reaches the color change temperature of the first reversible thermosensitive coating 2, the color of the first reversible thermosensitive coating is changed from the color at the normal temperature to the warning color, warning is provided for an operator, at the moment, the operator preferably stops using the embedding mold, and the embedding mold is reused after being cooled to the normal temperature; when the temperature of the embedding mold continuously rises to reach the color change temperature of the second reversible thermosensitive coating 3, the color of the second reversible thermosensitive coating 3 is changed from the normal temperature color to the warning color, at the moment, an operator should stop using the embedding mold immediately, place the mold in a ventilation place, and use the mold after cooling to the room temperature.
As can be seen from the above description, the utility model has the advantages that: the utility model discloses a reversible temperature sensing coating of coating on embedding mould, the temperature range of the place of embedding mould can be directly perceived to indicate when the embedding, can regard as whether choose this mould for use for the reference of follow-up work, is favorable to improving the preparation quality of tissue slice sample, and is favorable to the automatic instrument development in later stage, reaches and reduces artificial purpose.
Further, the first reversible thermosensitive coating 2 is a silver tetraiodomercuric acid coating.
As can be seen from the above description, silver tetraiodomercurate (Ag) is provided by the provision of a silver tetraiodomercurate coating2[HgI4]) Is yellow powder substance, the structure of which is tetragonal system, and the yellow powder substance is yellow at normal temperature; when the temperature is heated to more than 48 ℃, the structure of the material is converted into a cubic crystal system, the appearance is orange, and operators can be intuitively reminded of the approximate temperature of the embedded die.
Further, the second reversible thermosensitive coating 3 is a copper tetraiodomercuric acid coating.
As can be seen from the above description, by providing a copper tetraiodomercuric acid coating, copper tetraiodomercuric acid (CuHgI)4) Is a red powdery substance, has a tetragonal crystal structure at normal temperature, and has a red appearance; when the temperature is heated to above 71 ℃, the structure is converted into a cubic system, the appearance is brownish black, and an operator can be intuitively reminded not to touch the embedding mold at the moment.
Further, a draft angle of 0-2 degrees of vertical projection is arranged between the side wall 12 and the bottom wall 11.
As can be seen from the above description, with the setting of the draft angle, the coagulated tissue sample can be more easily pulled out by the cassette after the paraffin is coagulated.
Further, the outer edge of the top surface of the side wall 12 is provided with a protection groove 121, the protection groove 121 is made into an arc shape, and the surface of the protection groove 121 is provided with anti-skid convex points.
According to the description, the arrangement of the protection groove corresponds to fingers holding the mold, the positioning is accurate, the holding posture is comfortable, the mold is prevented from slipping and being damaged at high temperature, and the mold drawing action is easier.
Further, the protection groove 121 is made of a high temperature resistant silica gel material.
The first embodiment is as follows:
a medical heat-sensitive embedding mould comprises a mould body 1, a first reversible heat-sensitive coating 2 and a second reversible heat-sensitive coating 3;
the mould body 1 comprises a bottom wall 11 and a plurality of side walls 12;
the side walls 12 are vertically arranged around the bottom wall 11, and the side walls 12 and the bottom wall 11 jointly enclose a cavity with an opening at one end;
the first reversible thermosensitive coating 2 is arranged on the inner side surface of the side wall 12, and the color of the first reversible thermosensitive coating 2 is changed when the temperature reaches the color-changing temperature;
the second reversible thermosensitive coating 3 is arranged on the top surface of the side wall 12, and the color of the second reversible thermosensitive coating 3 changes when the temperature reaches the color-changing temperature;
the color change temperature of the first reversible thermosensitive coating 2 is lower than that of the second thermosensitive coating;
the first reversible thermosensitive coating 2 is a silver tetraiodomercuric acid coating;
the second reversible thermosensitive coating 3 is a copper tetraiodomercuric acid coating;
a draft angle with a vertical projection of 0-2 degrees is arranged between the side wall 12 and the bottom wall 11;
the outer edges of the top surfaces of the side walls 12 are provided with protective grooves 121, the protective grooves 121 are made into arc shapes, and the surfaces of the protective grooves 121 are provided with anti-skid convex points;
the protection groove 121 is made of a high temperature resistant silica gel material.
To sum up, the utility model provides a medical heat-sensitive embedding mould, through coating reversible heat-sensitive coating on the embedding mould, can directly perceivedly indicate the temperature range of embedding mould when embedding, can be used as the reference whether to select this mould for follow-up work, be favorable to improving the preparation quality of tissue slice sample, and be favorable to the development of the automatic instrument in later stage, reach and reduce artifical purpose;
through the arrangement of the silver tetraiodomercurate coating, the silver tetraiodomercurate (Ag)2[HgI4]) Is yellow powder substance, the structure of which is tetragonal system, and the yellow powder substance is yellow at normal temperature; when the temperature is heated to more than 48 ℃, the structure of the material is converted into a cubic crystal system, the appearance is orange, and operators can be intuitively reminded of the approximate temperature of the embedded die;
by arranging the copper tetraiodomercuric acid coating, the copper tetraiodomercuric acid (CuHgI)4) Is a red powdery substance, has a tetragonal crystal structure at normal temperature, and has a red appearance; when the temperature is heated to above 71 ℃, the structure is converted into a cubic crystal system, the appearance is brownish black, and an operator can be intuitively reminded of not touching the embedding mold at the moment;
through the arrangement of the drawing angles, after paraffin is solidified, the solidified tissue sample can be more easily drawn out through the embedding box;
through the setting of protection recess, correspond the finger of holding the mould, the location is accurate, holds the appearance comfortable, prevents mould slippage and high temperature damage, and can make the drawing action lighter.
The above mentioned is only the embodiment of the present invention, and not the limitation of the patent scope of the present invention, all the equivalent transformations made by the contents of the specification and the drawings, or the direct or indirect application in the related technical field, are included in the patent protection scope of the present invention.
Claims (6)
1. A medical thermosensitive embedding mold is characterized by comprising a mold body, a first reversible thermosensitive coating and a second reversible thermosensitive coating;
the mold body comprises a bottom wall and a plurality of side walls;
the side walls are vertically arranged around the bottom wall, and the side walls and the bottom wall jointly enclose a cavity with an opening at one end;
the first reversible thermosensitive coating is arranged on the inner side surface of the side wall, and the color of the first reversible thermosensitive coating is changed when the temperature of the first reversible thermosensitive coating reaches the color-changing temperature;
the second reversible thermosensitive coating is arranged on the top surface of the side wall, and the color of the second reversible thermosensitive coating changes when the temperature of the second reversible thermosensitive coating reaches the color-changing temperature;
the color change temperature of the first reversible thermosensitive coating is lower than the color change temperature of the second thermosensitive coating.
2. The medical heat-sensitive embedding mold according to claim 1, wherein the first reversible heat-sensitive coating is a silver tetraiodomercuric acid coating.
3. The medical thermosensitive embedding mold according to claim 1, wherein the second reversible thermosensitive coating is a copper tetraiodomercuric acid coating.
4. The medical thermosensitive embedding mold according to claim 1, wherein a draft angle of 0 ° -2 ° in vertical projection is provided between the side wall and the bottom wall.
5. The medical thermosensitive embedding mold according to claim 1, wherein the outer edges of the top surfaces of the side walls are each provided with a protective groove, the protective grooves are made into an arc shape, and the surfaces of the protective grooves are each provided with an anti-slip bump.
6. The medical thermosensitive embedding mold according to claim 5, wherein the protection groove is made of a high temperature resistant silica gel material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920900436.4U CN210119389U (en) | 2019-06-14 | 2019-06-14 | Medical heat-sensitive embedding mould |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920900436.4U CN210119389U (en) | 2019-06-14 | 2019-06-14 | Medical heat-sensitive embedding mould |
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| CN210119389U true CN210119389U (en) | 2020-02-28 |
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| CN201920900436.4U Active CN210119389U (en) | 2019-06-14 | 2019-06-14 | Medical heat-sensitive embedding mould |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110220763A (en) * | 2019-06-14 | 2019-09-10 | 福建省肿瘤医院（福建省肿瘤研究所、福建省癌症防治中心） | A kind of medical temperature-sensitive imbedded mold |
-
2019
- 2019-06-14 CN CN201920900436.4U patent/CN210119389U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110220763A (en) * | 2019-06-14 | 2019-09-10 | 福建省肿瘤医院（福建省肿瘤研究所、福建省癌症防治中心） | A kind of medical temperature-sensitive imbedded mold |
| CN110220763B (en) * | 2019-06-14 | 2024-07-12 | 福建省肿瘤医院（福建省肿瘤研究所、福建省癌症防治中心） | Medical thermosensitive embedding mould |
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