CN209916052U

CN209916052U - A swallowable capsule for extracting contents of digestive tract

Info

Publication number: CN209916052U
Application number: CN201920352322.0U
Authority: CN
Inventors: 王晶; 辛毅; 李炜玲; 茅卫锋; 臧师竹; 王佳; 肖智韬; 宋涛; 冯斌; 张翠丽
Original assignee: Dalian Medical University
Current assignee: Dalian Medical University
Priority date: 2019-03-20
Filing date: 2019-03-20
Publication date: 2020-01-10
Anticipated expiration: 2029-03-20

Abstract

The utility model discloses a swallowable be used for extracting capsule of alimentary canal content, its characterized in that: the capsule comprises an enteric coat (1), a shell (2) is arranged in the enteric coat (1), a top cover (3) is arranged at the opening of the top of the shell (2), a plurality of liquid inlet holes (4) are formed in the bottom of the shell (2), a collection hole (5) is formed in the side wall of the middle of the shell (2), two positioning holes (6) are symmetrically distributed in the shell (2) below the collection hole (5), enteric plugs (7) are fixed in the two positioning holes (6), a sampling inner shell (8) is connected in the shell (2) in a sliding mode, the sampling inner shell (8) is cylindrical and is provided with water swelling particles (9) at the top end, and meanwhile water swelling particles (9) are arranged in the shell (2) below the sampling inner shell (8).

Description

A swallowable capsule for extracting contents of digestive tract

Technical Field

The utility model relates to the field of medical treatment, in particular to a swallowable capsule for extracting contents in the alimentary canal.

Background

The micro-ecosystem refers to a unified biological system which is formed in a long-term evolution process and can independently perform mutual communication of substances, energy and genes (namely information) by taking host human beings, animals, plant tissues and cells and metabolites thereof as environments of normal microbial communities in a space with a certain structure. At present, the method for microecological research mainly extracts the feces of mammals to analyze the intestinal flora, and the characteristics of the flora at other parts of the digestive tract cannot be reflected. If the sampling can be directly carried out in the digestive tract of the mammal, the research significance of the micro-ecosystem is very important. However, there is no sampling device in the same field that can achieve the above purpose, so there is a need for a method or a device that can solve the problem.

Disclosure of Invention

The utility model provides a capsule which is reasonable in structure, convenient to use, painless, accurate and efficient and is used for extracting contents in the alimentary canal, aiming at solving the defects existing in the prior art.

The technical solution of the utility model is that: a swallowable capsule for extracting contents of the alimentary tract, comprising: the capsule comprises an enteric coat 1, a shell 2 is arranged in the enteric coat 1, a top cover 3 is arranged at the opening at the top of the shell 2, a plurality of liquid inlet holes 4 are formed in the bottom of the shell 2, a collection hole 5 is further formed in the side wall of the middle of the shell 2, two positioning holes 6 are symmetrically distributed on the shell 2 below the collection hole 5, enteric plugs 7 are fixed in the two positioning holes 6, a sampling inner shell 8 is connected to the shell 2 in a sliding mode, the sampling inner shell 8 is cylindrical and is provided with water swelling particles 9 below the sampling inner shell 8.

The water-swellable particles 9 are dry agaric particles.

Compared with the prior art, the utility model, have following advantage:

the capsule with the structure is designed aiming at the requirement of directly sampling from the digestive tract of mammals, and the capsule is designed into a special structure, and can be used for designing outer shell and inner shell structures which can move relatively according to the self digestion process of the intestinal tracts of the animals by utilizing the characteristics of enteric materials and water swelling materials, so that the contents in the digestive tract can be accurately and effectively extracted; the capsule has low cost and high plasticity, can adjust the size according to actual needs, and can be used in various fields such as production, scientific research, clinical examination, experiment, teaching and the like. The capsule is convenient to use and low in cost, and in the sampling process, a sampling object is painless and is not influenced by the external environment. Meanwhile, after sampling is started, manual operation or intervention is not needed completely, the capsule can complete sampling automatically, manual errors which are possibly generated can be avoided, and the efficiency of sampling is improved. Therefore, the method has multiple advantages, is particularly suitable for popularization and application in the field, and has very wide market prospect.

Drawings

Fig. 1 is a schematic structural diagram of an embodiment of the present invention.

Detailed Description

The following description will explain embodiments of the present invention with reference to the drawings. As shown in fig. 1: the utility model provides a swallowable capsule that is used for drawing alimentary canal content, includes enteric coat 1 be provided with casing 2 in the enteric coat 1, the open-top department of casing 2 disposes top cap 3, and a plurality of feed liquor holes 4 have been seted up to the bottom of casing 2 to still seted up on the middle part lateral wall of casing 2 and gathered hole 5, it has two locating holes 6 to gather the shell 2 of hole 5 below and distribute symmetrically, and these two locating holes 6 internal fixation have enteric plug 7, and it has sampling inner shell 8 to go back sliding connection in casing 2, sampling inner shell 8 is top open-ended cylindricly, still is provided with simultaneously in casing 2 of sampling inner shell 8 below and meets water inflation granule 9.

The water-swellable particles 9 are dry agaric particles, and the dry agaric particles are selected for use because the agaric can rapidly swell after encountering water and have no toxic or harmful effect on human bodies.

The working process of the swallowable capsule for extracting the contents in the alimentary canal of the embodiment of the utility model is as follows: firstly, placing water-swellable particles 9 at the bottommost part of a shell 2, then placing a sampling inner shell 8 in the shell 2, ensuring that the opening direction of the sampling inner shell 8 is consistent with the opening direction of the shell 2, and then transversely inserting an enteric plug 7 made of an enteric material into a positioning hole 6 to enable the enteric plug 7 to be blocked above the sampling inner shell 8, wherein the positioning hole 6 is positioned below a collecting hole 5, so that the collecting hole 5 cannot be blocked by the side wall of the sampling inner shell 8 after the enteric plug 7 is installed in place; finally, the top cover 3 is buckled and locked at the opening of the shell 2, and then the prepared shell 2 is put into the enteric coat 1;

when the content in the digestive tract needs to be sampled, a target swallows the capsule, after the capsule enters the small intestine of a human body, the enteric coat 1 on the outer part of the capsule can be dissolved, the content in the small intestine enters the inner cavity of the shell 2 through the collecting hole 5, meanwhile, the water-swelling particles 9 contacting liquid can swell and push the sampling inner shell 8 to move towards the direction close to the top cover 3, the enteric plug 7 supported by the enteric material can also dissolve, the sampling inner shell 8 losing the constraint moves in the shell 2 until the opening of the sampling inner shell contacts the inner end surface of the top cover 3, under the action of the water-swelling particles 9, the positive pressure is always present between the sampling inner shell 8 and the top cover 3, the sealing effect is achieved, namely, the collected content of the small intestine is sealed in the inner cavity of the sampling inner shell 8;

after the sampling inner shell 8 moves to the right position, the collecting hole 5 is closed, at the moment, the content collected in the sampling inner shell 8 can not be exchanged with the external content again,

after the shell 2 passes through the small intestine and the large intestine, the excrement is discharged out of the human body, and in the process, the content in the sampling inner shell 8 is not polluted; after the scientific research personnel retrieve it, only need open top cap 3 and take out the content in the sampling inner shell 8 can.

Claims

1. A swallowable capsule for extracting contents of the alimentary tract, comprising: the capsule comprises an enteric coat (1), a shell (2) is arranged in the enteric coat (1), a top cover (3) is arranged at the opening of the top of the shell (2), a plurality of liquid inlet holes (4) are formed in the bottom of the shell (2), a collection hole (5) is formed in the side wall of the middle of the shell (2), two positioning holes (6) are symmetrically distributed in the shell (2) below the collection hole (5), enteric plugs (7) are fixed in the two positioning holes (6), a sampling inner shell (8) is connected in the shell (2) in a sliding mode, the sampling inner shell (8) is cylindrical and is provided with water swelling particles (9) at the top end, and meanwhile water swelling particles (9) are arranged in the shell (2) below the sampling inner shell (8).

2. A swallowable capsule for extraction of gut contents according to claim 1, wherein: the water-swellable particles (9) are dry agaric particles.