CN209548162U - It is a kind of can natural degradation implantation material - Google Patents
It is a kind of can natural degradation implantation material Download PDFInfo
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- CN209548162U CN209548162U CN201821441837.XU CN201821441837U CN209548162U CN 209548162 U CN209548162 U CN 209548162U CN 201821441837 U CN201821441837 U CN 201821441837U CN 209548162 U CN209548162 U CN 209548162U
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- sacculus
- natural degradation
- implantation
- degradation material
- balloon body
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Abstract
The utility model discloses it is a kind of can natural degradation implantation material, for occupying patient body inner space, it includes balloon body, can natural degradation material and fluid delivery fitment, wherein fluid delivery fitment includes self-styled valve closing and the conduit being fixed on sacculus, fluid is injected into balloon interior by conduit, release channel can be opened after natural degradation material degradation, fluid is discharged from sacculus, wherein can natural degradation material be located at the surface of balloon body or the binding site of upper and lower level sacculus.Implantation material implantation human body is voluntarily degraded after for a period of time, opens release channel, carrys out induced degradation without using external force such as externally-applied magnetic field, microwave or change stomach inner pH values, sacculus can easily be discharged in vivo after natural degradation, take out without performing the operation, alleviate the pain of patient.
Description
Technical field
The utility model relates to implantation materials, specifically, be related to it is a kind of can natural degradation implantation material.
Background technique
Between past 20 years, obesity in global range, including Obesity Among Adultss disease, the elderly's obesity and blueness are few
The disease incidence of the obesity of year children is all rising violently.Root according to the statistics of the World Health Organization, the whole world in 2014 just have 15% at
Year women and 11% adult male obesity, which means that just having nearly 1,000,000,000 Obesity Among Adultss in the whole world in 2014.Do not allow to find pleasure in
What is seen is that Chinese population of being obese has caught up with and surpassed the U.S., and there are 89,600,000 populations of being obese in China in 2016, and (U.S.'s population of being obese is 8780
Ten thousand people), wherein male accounts for 43,200,000 people, and women accounts for 46,400,000 people.Fat usually occur together has hypertension, type-2 diabetes mellitus, ischemic
Property heart disease, joint dissolving time, sleeps apnea and certain tumours etc. at dyslipidemia, therefore, how effectively to control weight,
Prevention and control complication are the topics being concerned.
The primary treatment regimen of obesity includes: diet control, Spinal injury, drug therapy and operative treatment at present.So
And simple diet control, Spinal injury and drug therapy is extremely difficult to satisfied weight loss effect；Although loss of weight surgical effect is bright
It is aobvious, but be difficult to patient due to culture, medical level and postoperative complication etc. and received.Implantable medical devices subtract
Fertilizer, simulation surgery treat the mechanism of obesity, including intragastric balloon has just emerged these years because it is safe and simple, have
It imitates, is resilient, thus widely being paid close attention to, and the main effective means of the following weight-reducing can be become.
Foreign countries have had a few class intragastric balloons to list at present, especially need not move through the stomach that gastroscope is sent into and is voluntarily swallowed
Interior sacculus is the direction of the following weight-reducing means.Formula intragastric balloon is swallowed to be wrapped in capsule before effect, and be connected with one compared with
Long conduit, tube at one end are connected with the self-styled valve closing on intragastric balloon, and the other end stays in outside capsule and oral cavity.By the side of swallowing
The sacculus being wrapped in capsule and part conduit are sent into patient's stomach by formula, and capsule is degraded rapidly under gastric acid environment, from staying in
The extrabuccal conduit of patient holds the trandfer fluid into sacculus in vitro, and sacculus is expanded to expanded condition by initial compressive state.Stream
The self-styled valve closing that body forms fluid channel with conduit from patient's body extraction conduit, sacculus after conveying is automatically closed, with
Anti- fluid leakage.United States Patent (USP) US8974483B2 discloses such a implantation sacculus, referring specifically to Fig. 1.
Such as Fig. 1, this implantation sacculus disclosed in United States Patent (USP) US8974483B2 includes the water-setting being pre-placed in sacculus
Glue filler 108, after fluid conveys goal capsule 100 by conduit 200, filler 108 expands, by the sacculus 100 of compressive state
Expansion.Degradation material 106 positioned at balloon interior seals release channel in mechanical form, and degradation material 106 is being filled out
It fills under the action of object or other additional substances and degrades, open release channel.
The shortcomings that this structure is to be previously added filler 108 sacculus initial volume is made to become larger, and is unfavorable for patient and swallows.Together
When degradation material degradation need by filler or other additional substances, it is complicated for operation.Therefore, one kind how is designed to be not required to
It is pre-placed filler, while degradation material can be this field urgent problem with the implantation material of natural degradation.
Utility model content
It is of the existing technology in order to solve the problems, such as, the utility model provide it is a kind of it is novel can natural degradation implantation
Object, the implantation material without being pre-placed filler, can natural degradation material can voluntarily degrade, without additional substance.
The utility model provide it is a kind of can natural degradation implantation material, for occupying patient body inner space.Implantation material,
Including balloon body, can natural degradation material and fluid delivery fitment, wherein the fluid delivery fitment include be fixed on sacculus
Fluid is injected inside balloon body by the conduit, includes release in balloon body by self-styled valve closing and conduit in main body
Channel, which is characterized in that the release channel by it is described can natural degradation material seal, it is described can be after natural degradation material degradation
Release channel is opened, fluid is discharged from sacculus.
In one embodiment, can natural degradation material be polylactic acid base co-polymer, it is preferred that can natural degradation material
For polylactic acid-caprolactone copolymer or polylactic acid-trimethylene carbonate copolymer.Can natural degradation material be also possible to poly- pair
Dioxanone.
It include at least one release channel in balloon body, release channel quilt can the sealing of natural degradation material.
Preferably, can natural degradation material the surface of balloon body is incorporated in the form of sticking patch.It can natural degradation material
Shape can be ellipse, it is similar with capsule cross sectional shape used, when avoiding folded state to can natural degradation material mistake
Degree folds and causes to damage.
Preferably, can natural degradation material periphery and outer surface covering by least one layer of balloon body material or its
Coating made of its liquid-impermeable material, with control can natural degradation material and balloon body disengaging time.
In another embodiment, sacculus includes sacculus upper layer and sacculus lower layer, and sacculus upper layer and sacculus lower layer are on side
Overall structure is combined into along connection.Have at least one layer can natural degradation among the binding site of sacculus upper layer and sacculus lower layer
Material, formed can natural degradation release channel.
Can between natural degradation material and can natural degradation material include Nian Jie with the combination of balloon body or weld
It connects.
The implantation material of the utility model may be used as intragastric balloon, be also used as skin expansion sacculus.
It is according to the present utility model can natural degradation implantation material, be not pre-placed filler in sacculus, ensure that sacculus
It can be folded into smaller size smaller, patient is facilitated to swallow.Between balloon surface or upper and lower level sacculus for can natural degradation material, plant
It voluntarily degrades after entering human body for a period of time, opens release channel, it is outer without using externally-applied magnetic field, microwave or change stomach inner pH value etc.
Power carrys out induced degradation, and sacculus can easily be discharged in vivo after natural degradation, takes out without performing the operation, alleviates the pain of patient.
Detailed description of the invention
Attached drawing is used to provide a further understanding of the present invention, and constitutes part of specification, practical with this
Novel specific embodiment is used to explain the utility model together, does not constitute limitations of the present invention.
Fig. 1 is the schematic diagram according to the balloon structure of the prior art；
Fig. 2 is the structural schematic diagram according to the balloon system of one embodiment of the utility model；
Fig. 3 A be sacculus and can natural degradation material top view；
Fig. 3 B be can natural degradation material periphery and outer surface coating schematic diagram；
Fig. 4 be according to the sacculus of the utility model another embodiment, can natural degradation material and its exploded view；
Fig. 5 be the sacculus that assemble according to Fig. 4 with can natural degradation material top view；
Fig. 6 be can natural degradation material and sacculus upper and lower level side view.
Figure label: the edge 1-；2- tumble port；100- sacculus；102- sacculus shell；103- release channel；104- can be certainly
Right degradable material；105- coating；The outer 1051-；Edge in 1052-；106- degradation material；108- filler；110- sacculus
Upper layer；120- sacculus lower layer；200- conduit.
Specific embodiment
The utility model is further described With reference to embodiment, wherein being given for example only property of attached drawing
Illustrate, expression is only schematic diagram, rather than pictorial diagram, should not be understood as the limitation to this patent, in order to which this reality is better described
With novel specific embodiment, the certain components of attached drawing have omission, zoom in or out, and do not represent the size of actual product,
It will be understood by those skilled in the art that the omitting of some known structures and their instructions in the attached drawings are understandable, it is based on this reality
With the specific embodiment in novel, institute obtained by those of ordinary skill in the art without making creative efforts
There are other specific embodiments, fall within the protection scope of the utility model.
Referring to attached drawing 2, show according to one embodiment of the utility model can the structure of implantation material of natural degradation show
It is intended to.Preferably, which is et al. Ke balloon system, for example, intragastric balloon system, and those skilled in the art are easy
Expect that the balloon system of the utility model can be balloon system for other purposes, such as skin expansion sacculus.Et al. Ke
Balloon system includes: sacculus 100, conduit 200 and capsule (not shown).Sacculus 100 is wrapped in capsule before swallowing,
Described 200 one end of conduit is connected with the self-styled valve closing on sacculus 100.
The structure and production method of the balloon system of the embodiment are described in detail with reference to the accompanying drawings.Referring to Fig. 3 A, ball
Capsule shell 102 is made of flexible materials such as silicon rubber or polyurethane, has at least one opening on sacculus as release channel 103,
Can natural degradation material 104 release channel is sealed in the form of sticking patch, can natural degradation material 104 and sacculus shell 102
Combination includes being bonded or welded.
Can natural degradation material can be polylactic acid base co-polymer, it is preferable that can natural degradation material be polylactic acid-in oneself
Ester copolymer or polylactic acid-trimethylene carbonate copolymer, film thickness are 10-100 microns, are incorporated in balloon surface to releasing
Channel is put to seal.In other modes, can natural degradation material be polydioxanone.It can natural degradation material
It can be round, oval, rectangular or other arbitrary shapes.
Fig. 3 B show can natural degradation material 104 periphery and outer surface have one layer of coating 105, the coating
105 be ring structure, is made of balloon body material or other liquid-impermeable materials, outer 1051 and sacculus shell
102 are bonded or welded, it is interior along 1052 with can natural degradation material 104 be bonded or welded, with control can natural degradation material 104 with
The disengaging time of sacculus shell 102.
Fig. 4-6 show according to the utility model another embodiment can natural degradation implantation material structural representation
Figure, the embodiment and embodiment shown in Fig. 3 the difference is that: can natural degradation material be located at the knot of upper and lower level sacculus
Close position.The structure and production method of the balloon system of the embodiment are described in detail referring to Fig. 4-6.
Specifically, Fig. 4 show the sacculus 100, can natural degradation material 104 and its exploded view, the sacculus 100 wraps
Sacculus upper layer 110 and sacculus lower layer 120 are included, tumble port 2 is set on sacculus upper layer 110；Sacculus upper layer 110,120 and of sacculus lower layer
At least one layer can natural degradation material 104 connected by way of being bonded or welded at edge 1 and be combined into overall structure.It can be natural
Degradable material 104 is located among the binding site of sacculus upper layer 110 and sacculus lower layer 120, formed can natural degradation release it is logical
Road.It is overturn after the completion of combination by the tumble port 2 on sacculus upper layer 110.Finally by the tumble port 2 on sacculus upper layer 110
It is closed with sticking patch, forms complete sacculus, as shown in Figure 5.
Fig. 6 show can natural degradation material and upper and lower level sacculus side view, as shown in fig. 6, upper layer sacculus 110 and under
Layer sacculus 120 binding site among have at least one layer of degradation material 104, can natural degradation material 104 released because hydrolyzing to form
Channel is put, the structural intergrity of sacculus is destroyed, the filler outflow in sacculus.
The service condition of intragastric balloon according to the present utility model is as follows: patient, which swallows, includes sacculus 100 and part conduit
After 200 capsule, capsule dissolves rapidly under environment in stomach, and filling is conveyed into sacculus 100 by holding in vitro for conduit 200
Object, the filler can be liquid, be also possible to gas.Sacculus 100 becomes expanded state from initial squeezed state.Filling, which finishes, pulls out
Conduit 200 out, under the pressure of 100 inside stuffing of sacculus, self-styled valve closing is closed automatically, stops letting out for sacculus inner stuffing
Leakage.Sacculus 100 occupies stomach inner volume, achievees the purpose that loss of weight.It, can 104 water of natural degradation material after being implanted into human body for a period of time
Solution, release channel are opened, and the structural intergrity of sacculus 100 is destroyed, and sacculus inner stuffing is expelled in patient's stomach, after emptying
Sacculus shell 102 finally excluded naturally with gastrointestinal peristalsis in vitro.
It is according to the present utility model can natural degradation implantation material, be not pre-placed filler in sacculus 100, ensure that ball
Capsule can be folded into smaller size smaller, and patient is facilitated to swallow.Outside sacculus can natural degradation material 104 be can natural degradation material
Material, voluntarily degrades after being implanted into the patient a period of time, opens release channel, without using externally-applied magnetic field, microwave or changes stomach
The external force such as interior pH value carry out induced degradation, and sacculus shell 102 can easily be discharged in vivo after natural degradation, take out without performing the operation, and mitigate
The pain of patient.
While there has been shown and described that specific embodiment of the present utility model, for those of ordinary skill in the art
For, it is possible to understand that do not depart from the principles of the present invention and spirit in the case where, can to these specific embodiments into
The a variety of change, modification, replacement and modification of row, the scope of the utility model are defined by the appended claims and the equivalents thereof.
Claims (10)
1. a kind of implantation material, including balloon body, can natural degradation material and fluid delivery fitment, wherein the fluid conveying is attached
Part includes self-styled valve closing and the conduit being fixed in balloon body, is injected fluid inside balloon body by the conduit, ball
In capsule main body include release channel, which is characterized in that the release channel by it is described can natural degradation material seal, it is described can from
Release channel is opened after right degradable material degradation, fluid is discharged from sacculus.
2. implantation material according to claim 1, which is characterized in that include that at least one release is logical in the balloon body
Road, it is described can natural degradation material the surface of balloon body is incorporated in the form of sticking patch.
3. implantation material according to claim 2, it is characterised in that it is described can natural degradation material periphery and outer surface
The coating made of at least one layer of balloon body material or other liquid-impermeable materials is covered, it can natural degradation with control
The disengaging time of material and balloon body.
4. implantation material according to claim 3, which is characterized in that the coating is annular, outer and sacculus shell
Be bonded or welded, interior edge with can natural degradation material be bonded or welded.
5. implantation material according to claim 1, which is characterized in that the sacculus includes sacculus upper layer and sacculus lower layer, institute
State can natural degradation material be located at the binding site of upper and lower level sacculus, formed can natural degradation release channel.
6. implantation material according to claim 5, which is characterized in that the sacculus upper layer is arranged tumble port, under the sacculus
Layer and at least one layer can natural degradation material connect at edge and is combined into overall structure, combination is after the completion by the sacculus upper layer
On the tumble port overturn, the tumble port on the sacculus upper layer is closed with sticking patch after the completion, is formed complete
Sacculus.
7. the implantation material according to any one of claim 2-6, which is characterized in that can be between natural degradation material and can
The combination of natural degradation material and balloon body includes being bonded or welded.
8. according to the described in any item implantation materials of claim 2-6, which is characterized in that it is described can natural degradation material be with a thickness of
10-100 microns of film.
9. implantation material according to claim 2, which is characterized in that it is described can the shape of natural degradation material can be ellipse
Shape, round, rectangular or other arbitrary shapes.
10. implantation material according to claim 1, which is characterized in that the implantation material is intragastric balloon or skin expansion ball
Capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821441837.XU CN209548162U (en) | 2018-09-04 | 2018-09-04 | It is a kind of can natural degradation implantation material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821441837.XU CN209548162U (en) | 2018-09-04 | 2018-09-04 | It is a kind of can natural degradation implantation material |
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| Publication Number | Publication Date |
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| CN209548162U true CN209548162U (en) | 2019-10-29 |
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| CN201821441837.XU Active CN209548162U (en) | 2018-09-04 | 2018-09-04 | It is a kind of can natural degradation implantation material |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108852578A (en) * | 2018-09-04 | 2018-11-23 | 常州至善医疗科技有限公司 | It is a kind of can natural degradation implantation material |
| WO2022188617A1 (en) * | 2021-03-09 | 2022-09-15 | 常州至善医疗科技有限公司 | Closure and release structure for in-vivo implant |
-
2018
- 2018-09-04 CN CN201821441837.XU patent/CN209548162U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108852578A (en) * | 2018-09-04 | 2018-11-23 | 常州至善医疗科技有限公司 | It is a kind of can natural degradation implantation material |
| CN108852578B (en) * | 2018-09-04 | 2024-05-28 | 常州至善医疗科技有限公司 | Implant capable of being degraded naturally |
| WO2022188617A1 (en) * | 2021-03-09 | 2022-09-15 | 常州至善医疗科技有限公司 | Closure and release structure for in-vivo implant |
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