CN209187659U - A kind of collagen dressing of imbibition moisturizing - Google Patents
A kind of collagen dressing of imbibition moisturizing Download PDFInfo
- Publication number
- CN209187659U CN209187659U CN201820571792.1U CN201820571792U CN209187659U CN 209187659 U CN209187659 U CN 209187659U CN 201820571792 U CN201820571792 U CN 201820571792U CN 209187659 U CN209187659 U CN 209187659U
- Authority
- CN
- China
- Prior art keywords
- layer
- dressing
- imbibition
- imbibition moisturizing
- collagen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000005213 imbibition Methods 0.000 title claims abstract description 44
- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 43
- 102000008186 Collagen Human genes 0.000 title claims abstract description 34
- 108010035532 Collagen Proteins 0.000 title claims abstract description 34
- 229920001436 collagen Polymers 0.000 title claims abstract description 34
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
- 229920002545 silicone oil Polymers 0.000 claims description 6
- KJFMBFZCATUALV-UHFFFAOYSA-N phenolphthalein Chemical compound C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 claims description 5
- 206010022998 Irritability Diseases 0.000 claims description 3
- 229920005830 Polyurethane Foam Polymers 0.000 claims description 3
- 239000004820 Pressure-sensitive adhesive Substances 0.000 claims description 3
- 239000000853 adhesive Substances 0.000 claims description 3
- 230000001070 adhesive effect Effects 0.000 claims description 3
- 239000000835 fiber Substances 0.000 claims description 3
- 239000012528 membrane Substances 0.000 claims description 3
- 229920000747 poly(lactic acid) Polymers 0.000 claims description 3
- 239000004626 polylactic acid Substances 0.000 claims description 3
- 239000011496 polyurethane foam Substances 0.000 claims description 3
- 210000004872 soft tissue Anatomy 0.000 claims description 3
- 230000006378 damage Effects 0.000 abstract description 6
- 230000035876 healing Effects 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 2
- 208000027418 Wounds and injury Diseases 0.000 description 11
- 206010052428 Wound Diseases 0.000 description 10
- 229920001661 Chitosan Polymers 0.000 description 8
- 108090000765 processed proteins & peptides Proteins 0.000 description 5
- 241000276701 Oreochromis mossambicus Species 0.000 description 4
- 229920000615 alginic acid Polymers 0.000 description 4
- 235000010443 alginic acid Nutrition 0.000 description 4
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- -1 Metagin Ester Chemical class 0.000 description 3
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- 239000011734 sodium Substances 0.000 description 3
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- 150000001299 aldehydes Chemical class 0.000 description 2
- 235000010233 benzoic acid Nutrition 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 239000003431 cross linking reagent Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000000416 exudates and transudate Anatomy 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 235000010241 potassium sorbate Nutrition 0.000 description 2
- 239000004302 potassium sorbate Substances 0.000 description 2
- 229940069338 potassium sorbate Drugs 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- ZNZYKNKBJPZETN-WELNAUFTSA-N Dialdehyde 11678 Chemical compound N1C2=CC=CC=C2C2=C1[C@H](C[C@H](/C(=C/O)C(=O)OC)[C@@H](C=C)C=O)NCC2 ZNZYKNKBJPZETN-WELNAUFTSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical group O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 206010061217 Infestation Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000001126 Keratosis Diseases 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 102000015636 Oligopeptides Human genes 0.000 description 1
- 108010038807 Oligopeptides Proteins 0.000 description 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 1
- 206010061926 Purulence Diseases 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 229960002216 methylparaben Drugs 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
Abstract
The utility model provides a kind of collagen dressing of imbibition moisturizing, belongs to medicinal functional dressing technical field.The dressing is successively made of peeling layer, dressing layer, imbibition moisturizing layer and adhered layer from top to bottom；The imbibition moisturizing layer is in ellipticity; dressing layer is located above imbibition moisturizing layer and shape is leaf; the surface adhesion of dressing layer has the nethike embrane to prevent adhesion; the nethike embrane, which not only acts as the protection surface of a wound, prevents the effect of wound secondary damage; and the sepage of wound can be introduced imbibition moisturizing layer; to adjust the wet degree of wound, it is more conducive to the healing of wound.
Description
Technical field
The utility model relates to medical instrument functional dressing technical fields, and in particular to a kind of collagen egg of imbibition moisturizing
White dressing.
Background technique
Medical dressing refers to the medical material to cover sore, wound or other damages.Skin is by wound, burn, purulence
The a series of problem that can cause body after injury caused by the reasons such as turgescence canker, as bacterium infection, moisture and protein are excessive
Loss, endocrine and immune dysfunction etc., serious possibility threat to life.Therefore, after skin injury, it usually needs use skin
The substitute medical dressing of skin protects wound, prevents trauma surface infestation and serious dehydration, is provided with conducive to the wet of wound healing
Environment, wound healing.
Skin nursing dressing disclosed in existing technology is mainly by collagen peptide, chitosan, benzoic acid, Metagin
Ester, the composition such as potassium sorbate, preservative benzoic acid therein, methylparaben, potassium sorbate have centainly the UV skin damaged
Stimulation is unfavorable for red and swollen recession and the surface of a wound and restores；Lie. Ma et al. (Ma L, Gao C, Mao Z, et
al.Collagen/chitosan porous scaffolds with improved biostability for skin
Tissueengineering [J] Biomaterials, 2003,24 (26): 4833-4841.) use toxic reagent penta 2
Aldehyde makees the mechanical property and functional structure that crosslinking agent improves dressing for skin.Such as application No. is the patents of N201310463753.1
Application, which makees crosslinking agent with aldehydes, improves the performance of chitosan gel rubber dressing, wherein remaining and being crosslinking in penta in carboxymethyl chitosan
Dialdehyde is difficult to dispel, and the proliferation and migration to cell cause certain harm；Meanwhile aggravating the inflammatory reaction of wound, to corium
The collagen of layer causes secondary damage, is unfavorable for the healing of damaged skin.
With the development of technology, people have higher requirement to the performance of dressing.General dressing need to meet control and suction
Exudate, moisturizing, antibacterial, anti-inflammatory, the nontoxic performance requirements such as non-stimulated are received, however existing medical dressing does not have also mostly
Effect ideal in this way.
Utility model content
A kind of collagen of the imbibition moisturizing provided the purpose of this utility model is to overcome in the prior art insufficient
Albumen dressing.
To solve the above problems, the technical solution adopted in the utility model is:
A kind of collagen dressing of imbibition moisturizing, from top to bottom successively by peeling layer, dressing layer, imbibition moisturizing layer and viscous
Paste layer is constituted；The imbibition moisturizing layer is in ellipticity, and the dressing layer is located above the imbibition moisturizing layer and shape is leaf
Shape, the surface adhesion of the dressing layer have the nethike embrane to prevent adhesion.
Preferably, the peeling layer is Ge Laxin silicone oil paper, and the grammes per square metre of the Ge Laxin silicone oil paper is 40-90g/
m2。
Preferably, the imbibition moisturizing layer is by medical polyurethane foam or activated carbon fibre.
Preferably, the adhered layer is the medical pressure sensitive adhesive of low irritability.
Preferably, the dressing layer is composite collagen film.
Preferably, the composite collagen film is fine by Java tilapia skin collagen and chitosan, alginates, carboxymethyl
Plain sodium processing is tieed up to be prepared.
Preferably, the nethike embrane is netted polylactic acid membrane.
Preferably, the peeling layer and adhered layer are the identical rectangular or square of size.
Preferably, imbibition moisturizing layer can be completely covered in the peeling layer or adhered layer, and dressing layer can be protected by imbibition completely
Wet layer covering.
Preferably, the dressing layer and imbibition moisturizing layer pass through soft tissue medical adhesive tight bond.
The collagen that Java tilapia skin extracts is by two α (I) polypeptide chains and α (II) polypeptide chain triple helix at one
The fibrous glycoprotein of kind, nutritive value is high, rich in aliphatic amino acids such as glycine, lysine, proline and hydroxyprolines
Side chain and heterocyclic amino acid, especially oligopeptide have many advantages, such as more resistant to heat, acid and alkali-resistance, do not allow mutability, can be skin skin
Amino acid needed for collagen recombinates is supplemented, to promote collagenic supersession, repair impaired collagen structure.
The utility model have it is following the utility model has the advantages that
The utility model collagen film dressing layer is by collagen peptide and alginates, chitosan and carboxymethyl cellulose
Plain sodium processing is prepared, and the collagen film dressing natural no stimulation, biocompatibility is good, wherein alginates and carboxymethyl
There is sodium cellulosate good moisture retention can promote the aquation of keratoderma to promote Java tilapia skin collagen peptide
Transdermal absorption, the antimicrobial antiphlogistic activity of chitosan can assist in the treatment of the red and swollen and damaged symptom of skin；Collagen film dressing layer
Surface be attached with the nethike embrane to prevent adhesion, adhesion causes the secondary of skin when on the one hand can prevent dressing layer from contacting with wound surface
On the other hand superfluous wound exudate drainage can be diffused to imbibition moisturizing layer, to avoid wound overly moist and influence by damage
Comprehensive healing process is more conducive to the healing of the excessive surface of a wound of sepage.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of the collagen dressing of the imbibition moisturizing of embodiment 1；
Description of symbols: 1, peeling layer, 2, dressing layer, 3, imbibition moisturizing layer, 4, adhered layer.
Specific embodiment
The utility model is further described with reference to the accompanying drawing.Following embodiment is only used for clearly illustrating this
The technical solution of utility model, and cannot be used as a limitation the limitation protection scope of the utility model.Those skilled in the art are come
It says, the omitting of some known structures and their instructions in the attached drawings are understandable.Positional relationship is described in attached drawing to be only used for showing
Example property explanation, should not be understood as the limitation to this patent.
Embodiment 1
As shown in Figure 1, a kind of collagen dressing of imbibition moisturizing of the present embodiment, from top to bottom successively by peeling layer 1,
Dressing layer 2, imbibition moisturizing layer 3 and adhered layer 4 are constituted；The imbibition moisturizing layer 3 is in ellipticity, and dressing layer 2 is located at imbibition guarantor
Wet layer 3 above and shape be it is leaf, the surface adhesion of dressing layer 2 has the nethike embrane to prevent adhesion.
Peeling layer 1 is Ge Laxin silicone oil paper, and the grammes per square metre of the Ge Laxin silicone oil paper is 40-90g/m2；Imbibition moisturizing layer 3
By medical polyurethane foam, activated carbon fibre it is therein any one constitute；Adhered layer 4 by low irritability medical pressure sensitive adhesive structure
At；Dressing layer 2 is to be answered by Java tilapia skin collagen with what chitosan, alginates, sodium carboxymethylcellulose processing were prepared
Collagen film is closed, the nethike embrane to prevent adhesion is netted polylactic acid membrane.Wherein, peeling layer 1 and adhered layer 4 are that size is identical
Rectangular or square；Imbibition moisturizing layer can be completely covered in peeling layer 1 or adhered layer 4, and dressing layer 2 can be completely by imbibition moisturizing layer
3 coverings；Dressing layer 2 and imbibition moisturizing layer 3 pass through soft tissue medical adhesive tight bond.
In use, opening peeling layer 1, combine dressing layer 2 is directed at wound, adhered layer 4 is dabbed and is fixed on surrounding skin
It is upper.
Obviously, the above embodiments of the present invention is used for the purpose of clearly demonstrating examples for clearly illustrating the present invention,
And it is not limitations of the embodiments of the present invention.For those of ordinary skill in the art, it is stated upper
It can also be made other variations or changes in different ways on the basis of bright.There is no need and unable to give all embodiments
With exhaustion.Any modifications, equivalent replacements, and improvements made within the spirit and principle of the present invention etc. should all include
Within the protection scope of the utility model claims.
Claims (9)
1. a kind of collagen dressing of imbibition moisturizing, which is characterized in that from top to bottom successively by peeling layer, dressing layer, imbibition
Moisturizing layer and adhered layer are constituted；The imbibition moisturizing layer is in ellipticity, and the dressing layer is located above the imbibition moisturizing layer
And shape be it is leaf, the surface adhesion of the dressing layer has the nethike embrane to prevent adhesion.
2. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the peeling layer is
Lattice Racine silicone oil paper, the grammes per square metre of the Ge Laxin silicone oil paper are 40-90g/m2。
3. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the imbibition moisturizing
Layer is made of medical polyurethane foam or activated carbon fibre.
4. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the adhered layer is
The medical pressure sensitive adhesive of low irritability.
5. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the dressing layer is multiple
Close collagen film.
6. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the nethike embrane is netted
Polylactic acid membrane.
7. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the peeling layer and
Adhered layer is the identical rectangular or square of size.
8. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the peeling layer and
The imbibition moisturizing layer can be completely covered in adhered layer, and the dressing layer can be covered by the imbibition moisturizing layer completely.
9. a kind of collagen dressing of imbibition moisturizing according to claim 1, which is characterized in that the dressing layer with
Imbibition moisturizing layer passes through soft tissue medical adhesive tight bond.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820571792.1U CN209187659U (en) | 2018-04-20 | 2018-04-20 | A kind of collagen dressing of imbibition moisturizing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820571792.1U CN209187659U (en) | 2018-04-20 | 2018-04-20 | A kind of collagen dressing of imbibition moisturizing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209187659U true CN209187659U (en) | 2019-08-02 |
Family
ID=67404071
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820571792.1U Expired - Fee Related CN209187659U (en) | 2018-04-20 | 2018-04-20 | A kind of collagen dressing of imbibition moisturizing |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209187659U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111557792A (en) * | 2020-06-17 | 2020-08-21 | 广东泰宝医疗器械技术研究院有限公司 | Composite medical dressing capable of developing color |
-
2018
- 2018-04-20 CN CN201820571792.1U patent/CN209187659U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111557792A (en) * | 2020-06-17 | 2020-08-21 | 广东泰宝医疗器械技术研究院有限公司 | Composite medical dressing capable of developing color |
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|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190802 |