CN209075641U - A kind of Blood index purification device - Google Patents
A kind of Blood index purification device Download PDFInfo
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- CN209075641U CN209075641U CN201820914989.0U CN201820914989U CN209075641U CN 209075641 U CN209075641 U CN 209075641U CN 201820914989 U CN201820914989 U CN 201820914989U CN 209075641 U CN209075641 U CN 209075641U
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Abstract
The utility model relates to a kind of Blood index purification device, which is directly separated blood using dialysis separator device, and the weak solution for the small flow separated is after the fixed toxin of absorber, then the Blood index purification techniques directly mixed with the concentrated solution of larger flow.The device eliminates the dialysis fluid circulation in conventional blood adsorption and purification technology, it is directly separated using blood, small flow weak solution adsorption and purification technology, device compact provides new technical thought for the development of portable blood clearing machine, and economy, social effect are huge.
Description
Technical field
The utility model relates to a kind of Blood index purification devices, in particular to a kind of to be directly separated blood using dialyzer
Liquid, the weak solution of the small flow separated is after the fixed toxin of absorber, then directly mixes with the concentrated solution of larger flow
Blood index purification techniques belongs to apparatus for purifying blood technical field.
Background technique
Haemodialysis is a kind of external dialysis treatment for filtering toxin from the blood of patient using haemodialysis control unit.At present
Most of haemodialysis control units generally comprise computer, fluid pump, blood lines, dialysate lines, dialyzer and for discharging
The tapping line of dialysis solution.Blood passes through the dialyzer comprising semi-permeable membrane in haemodialysis control unit.Semi-permeable membrane is by side
Blood is separated with the dialysis solution at another layer.Dialyzer removes waste, toxin and excessive water, purified blood from blood
Liquid returns to human body.Waste product and toxin are transferred in dialysis solution by semi-permeable membrane from blood, are used in single dialysis treatment
Dialyzate about 90-120 liter, then directly abandon or processing after discharge.Obviously, a large amount of used dialyzate will increase dialysis
Cost.Due to the substance that the needs that dialyzate can also include various concentration are introduced into blood flow by diffusion, such as drug, grape
Sugar, these components when passing through dialyzer can not completely into blood, thus also can some be discharged with discarded dialyzate；
In addition, there are also the beneficial components of some pairs of human bodies to enter discarded dialyzate by semi-permeable membrane in blood.Above-mentioned various factors is led
It causes the increased costs of haemodialysis, waste to increase, also can cause environmental pollution.Therefore, many dialyzate recycling benefits are produced
With technology, typical technology is as follows:
A kind of dialysate regeneration system for portable human dialysis of Chemica Technologies Inc., U.S. application, in
State's number of patent application is 200480038117.3, and the request for data of PCT application is PCT/US2004/043546
(2004.12.22) was authorized, Authorization Notice No. CN1897993B on February 08th, 2012, the signal of core technology process
Figure is as shown in Fig. 1.The key technology of the patent uses a kind of dialysate regeneration room 14, can selectively retain toxin side by side
The toxin trap of the cation of selection is denounceed, wherein the ion selection urase that the toxin trap includes ion selection barrier is consolidated
Determine activated carbon fiber.The advantages of technology is that process is simple, structurally reasonable, easy to carry.But it also has the shortcomings that certain: due to
The adsorbent adsorption area low thus required into the toxin concentration in the dialyzate of dialysate regeneration room is big, unit volume
Adsorbent adsorption efficiency is lower, and adsorbent inventory is more.
Chinese patent (application number: 201510106383.5) provides a kind of dialysate regeneration device, using reverse osmosis group
Part and electric catalysis reactor based on BDD electrode utilize the very wide potential window of the electric catalysis reactor based on BDD electrode and low
Adsorption capacity, oxidation process is very efficient, effectively can convert and remove waste product and toxin in dialyzate, device it is continuous
Runnability is good.But its also have the shortcomings that it is certain, if electric catalysis reactor may following components generate catalytic action, cause to become
Property or generate the substance that is harmful to the human body, such as penetrate the blood of human body Hubeiwan of dialyzate, be not fully utilized in dialyzate
Needs pass through the substance (such as drug or glucose) that is introduced into blood of diffusion.
Therefore above-mentioned technology how is solved the problems, such as, using few use or even without the blood purification skill of dialyzate
Art becomes one of hot subject of the area research.
Summary of the invention
The utility model is in order to solve the problems existing in the prior art, to be directly separated blood using dialysis separator device, point
The weak solution for separating out the small flow come is inhaled after the fixed toxin of absorber, then with the blood that the concentrated solution of larger flow directly mixes
Attached purification techniques.The device eliminates the dialysis fluid circulation in conventional blood adsorption and purification technology, is directly divided using blood
From, small flow weak solution adsorption and purification technology, device compact provides new skill for the development of portable blood clearing machine
Art thinking.
The purpose of this utility model is realized by following measures:
A kind of Blood index purification device, it is characterised in that:
The Blood index purification device includes dialysis separator 32, absorber 37: blood of human body is drawn pipeline 30 and is drawn
Blood out is sent into dialysis separator 32 after the pressurization of blood booster pump 31, and it is molten to isolate higher concentration from dialysis separator 32
Liquid and lower concentration solutions, wherein higher concentration solution comes out from the dope side 32-1 of dialysis separator 32, through dope outlet
Line 33 is sent into mixer 34, and lower concentration solutions come out from the thin liquid side 32-2 of dialysis separator 32, through thin liquid booster pump 35, dilute
Solution pipeline 36 is sent into absorber 37, and thin liquid outlet line 38 is sent into mixer 34 after the solution that absorber 37 comes out is purified,
Human body 40 is returned to through blood return tube line 39 through the mixed blood of mixer 34, to form blood of human body adsorption cleaning circulation
Process.
The dialysis separator 32 includes shell, dope side 32-1, semipermeable membrane, thin liquid side 32-2.
The absorber 37 is provided with adsorbent.
The adsorbent includes specific adsorption material and/or non-specific adsorption material.
The specific adsorption material includes but is not limited to beta-cyclodextrin, the compound of beta-cyclodextrin group, β-ring paste
The modified compound of compound, beta-cyclodextrin chemical modification after essence crosslinking, beta-cyclodextrin are through the modified chemical combination of chemical modification
The high molecular material that object is polymerized, the n-alkyl chain group containing 6 carbon or more compound in any one or it
Between arbitrary proportion combination.
The non-specific adsorption material includes at least active carbon, any one or appointing between them in molecular sieve
The combination of meaning ratio.
The adsorbent is using the organosilicon material compatible with blood of human body as carrier.
The adsorbent is for adsorbing urea nitrogen.
The adsorbent is for adsorbing creatinine.
The adsorbent is for adsorbing phosphate.
Semipermeable membrane in the dialysis separator 32 is used to separate small molecule waste product and the toxin in blood, including
But it is not limited to urea nitrogen, creatinine and other small organic human waste molecules, water.
The Blood index purification device is equipped with necessary blood anticoagulant and facility is added.
The Blood index purification device is equipped with the facility of necessary replacement absorber and adsorbent.
The Blood index purification device is equipped with necessary detection instrument, valve and control system etc..
When needing, it is equipped with ultrafilter, extra moisture is isolated from Blood index purification device.
The unaccounted technical characteristic of the utility model is carried out mating using the mature prior art.
The utility model has the advantages that compared with prior art
1, this Blood index purification device eliminates the dialysis fluid circulation of conventional blood purification techniques, and device is small and exquisite tight
It gathers, provides new possible technique thinking for the development of portable blood clearing machine；
2, the substance such as drug, glucose etc. for needing to be introduced into blood flow by diffusion, can be directly added into mixer, enter
Human body efficiently utilizes；
3, using dialysis separator, absorber combination purification technology, the weak solution come out from dialysis separator uses small stream
Measure adsorption cleaning toxin, adsorbent material in absorber effectively avoided to contact with the direct of macromolecular substances in blood, eliminate because
This issuable harm；The small-molecule substance loss beneficial to human body caused by traditional dialyzate circulation is effectively avoided.
Detailed description of the invention
Fig. 1 is a kind of dialysate regeneration system flow diagram for portable human dialysis.
Fig. 2 is a kind of Blood index purification device schematic diagram of the utility model.
In Fig. 2: 30- blood draws pipeline；31- blood booster pump；32- dialysis separator；32-1- dope side； 32-2-
Thin liquid side；33- dope outlet line；34- mixer；35- thin liquid booster pump；36- weak solution pipeline；37- absorber；38- is net
Thin liquid outlet line after change；39- blood reflux pipeline；40- human body.
Specific embodiment
The utility model is described in further detail below in conjunction with the drawings and specific embodiments.
Embodiment 1:
As shown in Fig. 2, a kind of Blood index purification device that embodiment uses:
The Blood index purification device includes dialysis separator 32, absorber 37: blood of human body draws what pipeline 30 was drawn
Blood through blood booster pump 31 pressurization after, be sent into dialysis separator 32, from dialysis separator 32 isolate higher concentration solution and
Lower concentration solutions, wherein higher concentration solution comes out from the dope side 32-1 of dialysis separator 32, through dope outlet line 33
It is sent into mixer 34, lower concentration solutions come out from the thin liquid side 32-2 of dialysis separator 32, through thin liquid booster pump 35, dilute molten
Liquid pipe line 36 is sent into absorber 37, and thin liquid outlet line 38 is sent into mixer 34, warp after the solution that absorber 37 comes out is purified
The mixed blood of mixer 34 returns to human body 40 through blood return tube line 39, is circulated throughout to form blood of human body adsorption cleaning
Journey.
The dialysis separator 32 includes shell, dope side 32-1, semipermeable membrane, thin liquid side 32-2.
The absorber 37 is provided with adsorbent.
The adsorbent uses non-specific adsorption material.
The non-specific adsorption material includes activated carbon fibre.
The adsorbent is using the organosilicon material compatible with blood of human body as carrier.
The adsorbent is for adsorbing urea nitrogen.
The adsorbent is for adsorbing creatinine.
The adsorbent is for adsorbing phosphate.
Semipermeable membrane in the dialysis separator 32 is used to separate small molecule waste product and the toxin in blood, including
But it is not limited to urea nitrogen, creatinine and other small organic human waste molecules, water.
The Blood index purification device is equipped with necessary blood anticoagulant and facility is added.
The Blood index purification device is equipped with necessary detection instrument, valve and control system etc..
When needing, it is equipped with ultrafilter, extra moisture is isolated from Blood index purification device.
The unaccounted technical characteristic of the utility model is carried out mating using the mature prior art.
Although the utility model has been described by way of example and in terms of the preferred embodiments, they be not for limiting the utility model,
It is any to be familiar with this field technical professional, in the spirit and scope for not departing from the utility model, it can make various simply to repair
Change, equivalent variations, still falls within the protection scope of technical solutions of the utility model.
Claims (2)
1. a kind of Blood index purification device, it is characterised in that:
The Blood index purification device includes dialysis separator (32), absorber (37): blood of human body draws pipeline (30)
The blood of extraction through blood booster pump (31) be pressurized after, be sent into dialysis separator (32), from dialysis separator (32) isolate compared with
Highly concentrated solution and lower concentration solutions, wherein higher concentration solution comes out from the dope side (32-1) of dialysis separator (32),
Mixer (34) are sent into through dope outlet line (33), lower concentration solutions go out from the thin liquid side (32-2) of dialysis separator (32)
Come, is sent into absorber (37) through thin liquid booster pump (35), weak solution pipeline (36), the solution come out from absorber (37) is purified
Thin liquid outlet line (38) is sent into mixer (34) afterwards, returns through mixer (34) mixed blood through blood return tube line (39)
The Huis' body (40), to form blood of human body adsorption cleaning cyclic process.
2. Blood index purification device according to claim 1, it is characterised in that:
The dialysis separator (32) includes shell, dope side (32-1), semipermeable membrane, thin liquid side (32-2).
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| Application Number | Priority Date | Filing Date | Title |
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| CN201820914989.0U CN209075641U (en) | 2018-06-13 | 2018-06-13 | A kind of Blood index purification device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201820914989.0U CN209075641U (en) | 2018-06-13 | 2018-06-13 | A kind of Blood index purification device |
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| CN209075641U true CN209075641U (en) | 2019-07-09 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108785772A (en) * | 2018-06-13 | 2018-11-13 | 上海健康医学院 | A kind of Blood index purifier |
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2018
- 2018-06-13 CN CN201820914989.0U patent/CN209075641U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108785772A (en) * | 2018-06-13 | 2018-11-13 | 上海健康医学院 | A kind of Blood index purifier |
| CN108785772B (en) * | 2018-06-13 | 2024-04-09 | 上海健康医学院 | Blood adsorption purification device |
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