CN209010514U - A kind of tumour cell separator that internal medicine uses - Google Patents
A kind of tumour cell separator that internal medicine uses Download PDFInfo
- Publication number
- CN209010514U CN209010514U CN201821718944.2U CN201821718944U CN209010514U CN 209010514 U CN209010514 U CN 209010514U CN 201821718944 U CN201821718944 U CN 201821718944U CN 209010514 U CN209010514 U CN 209010514U
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- CN
- China
- Prior art keywords
- strainer
- baffle
- tumour cell
- separator box
- concentrator bowl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
The utility model relates to cell separation equipment technical fields, and disclose a kind of tumour cell separator that internal medicine uses, including separator box, the bottom for separating box cavity is equipped with mounting groove, the bottom of mounting groove is fixedly installed with motor, the output end of motor is fixedly connected by retarder with one end of drive rod, the other end of drive rod through mounting groove top and be fixedly connected in the middle part of connecting plate bottom end, the top of connecting plate is fixedly connected with the bottom of concentrator bowl, the side of concentrator bowl is successively fixedly installed with the first strainer, the second strainer and third strainer from top to bottom.The tumour cell separator that the internal medicine uses, pass through being used cooperatively for the first strainer, the second strainer, third strainer, first baffle and second baffle, cell liquid is carried out to repeatedly different separation, the different cell of volume is separated, to obtain required tumour cell, the problem of avoiding because the volume of tumour cell is different, causing separation failure, improves the efficiency of separation.
Description
Technical field
The utility model relates to cell separation equipment technical field, the specially a kind of tumour cell that internal medicine uses separation dress
It sets.
Background technique
Cell separation technology includes centrifugation technique, flow cytometry and cell electrophoresis, and centrifugation is research such as nucleus, line grain
Body, golgiosome, lysosome and microbody and various macromolecular basic means.
Existing tumour cell separator when in use, since the size of tumour cell is there is biggish difference, because
This, often there is a situation where separation failure or calculating error, affects the treatment work of cell when being separated, in addition,
In separation, bulky cell often blocks the mesh of strainer, and the cell of small volume is caused to be difficult to go out from strainer,
So that cell separating effect is bad, the utility model provides a kind of tumour cell separator that internal medicine uses thus.
Utility model content
In view of the deficiencies of the prior art, the utility model provides a kind of tumour cell separator that internal medicine uses, tool
The advantages of standby separating for several times, good separating effect, solves existing tumour cell separator when in use, due to tumour cell
Size there is biggish differences, therefore when being separated, often there is a situation where separation failure or calculate error, shadow
Rung the treatment work of cell, in addition, separation when, bulky cell often blocks the mesh of strainer, cause volume compared with
Small cell is difficult to go out from strainer, so that the problem that cell separating effect is bad.
The utility model provides the following technical solutions: a kind of tumour cell separator that internal medicine uses, including separator box,
The bottom of the separation box cavity is equipped with mounting groove, and the bottom of the mounting groove is fixedly installed with motor, the output of the motor
End is fixedly connected by retarder with one end of drive rod, the other end of the drive rod run through the top of mounting groove and with connection
Board bottom is fixedly connected in the middle part of end, and the top of the connecting plate is fixedly connected with the bottom of concentrator bowl, the side of the concentrator bowl
Successively be fixedly installed with the first strainer, the second strainer and third strainer from top to bottom, first strainer and the second strainer it is outer
Movable sleeve is connected to first baffle and second baffle respectively for side, and one end of the first baffle and second baffle goes out liquid with first respectively
One end of pipe and the second outlet tube penetrates through connection, the other end of first outlet tube and the second outlet tube respectively with separator box
Side perforation connects, and is fixedly installed with sealing cover at the top of the concentrator bowl, the middle part fixing sleeve on the sealing cover top is connected to
Inlet tube, one end of the inlet tube penetrate through connection through sealing cover and with the separating tube of centrifugation tube inner chamber, the inlet tube
The other end runs through and extends to the outside of separator box, and the bottom of the separator box side is fixedly installed with third outlet tube.
Preferably, the bottom of the separation box cavity is equipped with skewed slot, the extreme lower position of the separator box intracavity bottom skewed slot
Higher than the bottom of third outlet tube.
Preferably, the shape of the concentrator bowl is cylinder, and the diameter value of the concentrator bowl bottom is less than at the top of concentrator bowl
Diameter value.
Preferably, the mesh size of first strainer, the second strainer and third strainer is not identical, first strainer and
The quantity of second strainer is four, and first strainer and the second strainer are not point-blank.
Preferably, the first baffle and second baffle are fixedly mounted on the side wall of separation box cavity, and described first
One end that baffle and second baffle are connect with concentrator bowl is higher than one end that first baffle and second baffle are connect with separator box.
Preferably, the both ends of the separating tube are higher than the middle part of separating tube, and the length value of the separating tube is less than separator box
The diameter value of inner cavity top.
Be compared with the prior art, the utility model have it is following the utility model has the advantages that
1, the tumour cell separator that the internal medicine uses passes through the first strainer, the second strainer, third strainer, first gear
Plate and second baffle are used cooperatively, and cell liquid is carried out to repeatedly different separation, the different cell of volume is separated, from
And the problem of obtaining required tumour cell, avoiding because the volume of tumour cell is different, cause separation failure, improve separation
Efficiency.
2, the tumour cell separator that the internal medicine uses will by being used cooperatively for sealing cover, inlet tube and separating tube
Cell liquid in inlet tube is sprayed onto the surface of third strainer by separating tube, avoids because bulky cell is often blocked
The mesh of strainer causes the cell of small volume to be difficult to go out from strainer, so that the problem that cell separating effect is bad, is improved
The effect of cell separation.
Detailed description of the invention
FIG. 1 is a schematic structural view of the utility model；
Fig. 2 is the first strainer of the utility model structure schematic diagram.
In figure: 1, separator box；2, mounting groove；3, motor；4, retarder；5, drive rod；6, connecting plate；7, concentrator bowl；8,
First strainer；9, the second strainer；10, third strainer；11, first baffle；12, second baffle；13, the first outlet tube；14, second
Outlet tube；15, sealing cover；16, inlet tube；17, separating tube；18, third outlet tube.
Specific embodiment
The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model
Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole
Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work
Every other embodiment obtained, fall within the protection scope of the utility model.
A kind of tumour cell separator that internal medicine uses referring to FIG. 1-2, including separator box 1,1 inner cavity of separator box
Bottom is equipped with skewed slot, and the extreme lower position of 1 intracavity bottom skewed slot of separator box is higher than the bottom of third outlet tube 18, passes through separator box 1
The skewed slot of bottom, the cell liquid for isolating the first strainer 8 are preferably flowed out from third outlet tube 18, while guaranteeing not having thin
Cytosol remains between separator box 1 and third outlet tube 18, and the bottom of 1 inner cavity of separator box is equipped with mounting groove 2, the bottom of mounting groove 2
Portion is fixedly installed with motor 3, and the output end of the model Y80M2-2 of motor 3, motor 3 pass through retarder 4 and the one of drive rod 5
End is fixedly connected, the other end of drive rod 5 through mounting groove 2 top and be fixedly connected in the middle part of 6 bottom end of connecting plate, connect
The top of plate 6 is fixedly connected with the bottom of concentrator bowl 7, and the shape of concentrator bowl 7 is cylinder, and the diameter value of 7 bottom of concentrator bowl is small
Diameter value in 7 top of concentrator bowl is separated cell liquid from different location by concentrator bowl 7, to isolate required
Tumour cell, the side of concentrator bowl 7 are successively fixedly installed with the first strainer 8, the second strainer 9 and third strainer 10 from top to bottom,
The mesh size of first strainer 8, the second strainer 9 and third strainer 10 is not identical, and the quantity of the first strainer 8 and the second strainer 9 is equal
It is four, the first strainer 8 and the second strainer 9 point-blank, do not pass through the first strainer 8, the second strainer 9 and third strainer 10
The difference of mesh size, cell liquid respectively is isolated by, thus selected according to different size of tumour cell it is separated go out
Cell liquid, movable sleeve is connected to first baffle 11 and second baffle 12 respectively in the outside of the first strainer 8 and the second strainer 9, first
Baffle 11 and second baffle 12 are fixedly mounted on the side wall of 1 inner cavity of separator box, first baffle 11 and second baffle 12 with from
One end that heart cylinder 7 connects is higher than one end that first baffle 11 and second baffle 12 are connect with separator box 1, passes through 11 He of first baffle
The cell liquid that second baffle 12 isolates the second strainer 9 and third strainer 10 is collected, then from the first outlet tube 13 and second
Outlet tube 14 is discharged, one end of first baffle 11 and second baffle 12 respectively with the first outlet tube 13 and the second outlet tube 14 one
The other end of end perforation connection, the first outlet tube 13 and the second outlet tube 14 is penetrated through with the side of separator box 1 respectively to be connected, centrifugation
The top of cylinder 7 is fixedly installed with sealing cover 15, and the middle part fixing sleeve on 15 top of sealing cover is connected to inlet tube 16, and the one of inlet tube 16
End penetrates through connection through sealing cover 15 and with the separating tube 17 of 7 inner cavity of concentrator bowl, and the both ends of separating tube 17 are higher than separating tube 17
Middle part, the diameter value that the length value of separating tube 17 is less than 1 inner cavity top of separator box are conveyed inlet tube 16 by separating tube 17
The cell liquid come in is sprayed onto the surface of third strainer 10, is uniformly dispersed in cell on mesh, to make the separation of cell
More completely, the other end of inlet tube 16 runs through and extends to the outside of separator box 1, and the bottom of 1 side of separator box is fixedly mounted
There is third outlet tube 18.
Working principle drives drive rod 5 to rotate, makes connecting plate 6 and concentrator bowl 7 firstly, opening motor 3 by retarder 4
Rotation, is then transported to separating tube 17 from inlet tube 16 for cell liquid, passes through third strainer 10, the second strainer 9 and the first strainer 8
To cell liquid separating for several times, the cell liquid isolated is respectively from the first outlet tube 13, the second outlet tube 14 and third outlet tube 18
It separates.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality
Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation
In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to
Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those
Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment
Intrinsic element.
While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art,
It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired
Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.
Claims (6)
1. a kind of tumour cell separator that internal medicine uses, including separator box (1), it is characterised in that: in the separator box (1)
The bottom of chamber is equipped with mounting groove (2), and the bottom of the mounting groove (2) is fixedly installed with motor (3), the output of the motor (3)
End is fixedly connected by retarder (4) with one end of drive rod (5), and the other end of the drive rod (5) is through mounting groove (2)
Top and be fixedly connected in the middle part of connecting plate (6) bottom end, the top of the connecting plate (6) and the bottom of concentrator bowl (7) are fixed
Connection, the side of the concentrator bowl (7) are successively fixedly installed with the first strainer (8) from top to bottom, the second strainer (9) and third filter
Movable sleeve is connected to first baffle (11) and second baffle respectively in the outside of net (10), first strainer (8) and the second strainer (9)
(12), one end of the first baffle (11) and second baffle (12) respectively with the first outlet tube (13) and the second outlet tube (14)
One end penetrate through connection, the other end of first outlet tube (13) and the second outlet tube (14) respectively with separator box (1) one
Side perforation connects, and is fixedly installed with sealing cover (15) at the top of the concentrator bowl (7), and the middle part on sealing cover (15) top is solid
Surely it is socketed with inlet tube (16), sealing cover (15) and the liquid separation with concentrator bowl (7) inner cavity are run through in one end of the inlet tube (16)
(17) perforation connection is managed, the other end of the inlet tube (16) runs through and extend to the outside of separator box (1), the separator box
(1) bottom of side is fixedly installed with third outlet tube (18).
2. the tumour cell separator that a kind of internal medicine according to claim 1 uses, it is characterised in that: the separator box
(1) bottom of inner cavity is equipped with skewed slot, and the extreme lower position of separator box (1) the intracavity bottom skewed slot is higher than third outlet tube (18)
Bottom.
3. the tumour cell separator that a kind of internal medicine according to claim 1 uses, it is characterised in that: the concentrator bowl
(7) shape is cylinder, and the diameter value of concentrator bowl (7) bottom is less than the diameter value at the top of concentrator bowl (7).
4. the tumour cell separator that a kind of internal medicine according to claim 1 uses, it is characterised in that: first filter
The mesh size of net (8), the second strainer (9) and third strainer (10) is not identical, first strainer (8) and the second strainer (9)
Quantity be four, first strainer (8) and the second strainer (9) are not point-blank.
5. the tumour cell separator that a kind of internal medicine according to claim 1 uses, it is characterised in that: the first gear
Plate (11) and second baffle (12) are fixedly mounted on the side wall of separator box (1) inner cavity, the first baffle (11) and second
One end that baffle (12) is connect with concentrator bowl (7) is connect higher than first baffle (11) and second baffle (12) with separator box (1)
One end.
6. the tumour cell separator that a kind of internal medicine according to claim 1 uses, it is characterised in that: the separating tube
(17) both ends are higher than the middle part of separating tube (17), and the length value of the separating tube (17) is less than separator box (1) inner cavity top
Diameter value.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821718944.2U CN209010514U (en) | 2018-10-23 | 2018-10-23 | A kind of tumour cell separator that internal medicine uses |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201821718944.2U CN209010514U (en) | 2018-10-23 | 2018-10-23 | A kind of tumour cell separator that internal medicine uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209010514U true CN209010514U (en) | 2019-06-21 |
Family
ID=66839613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201821718944.2U Expired - Fee Related CN209010514U (en) | 2018-10-23 | 2018-10-23 | A kind of tumour cell separator that internal medicine uses |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209010514U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111073798A (en) * | 2020-03-04 | 2020-04-28 | 山东第一医科大学(山东省医学科学院) | Centrifugal circulation tumor cell step-by-step separation device |
| CN112899153A (en) * | 2021-04-21 | 2021-06-04 | 江苏省疾病预防控制中心(江苏省公共卫生研究院) | Leukemia cell separation and extraction device |
-
2018
- 2018-10-23 CN CN201821718944.2U patent/CN209010514U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111073798A (en) * | 2020-03-04 | 2020-04-28 | 山东第一医科大学(山东省医学科学院) | Centrifugal circulation tumor cell step-by-step separation device |
| CN111073798B (en) * | 2020-03-04 | 2024-03-08 | 山东第一医科大学(山东省医学科学院) | Centrifugal circulation tumor cell step-by-step separation device |
| CN112899153A (en) * | 2021-04-21 | 2021-06-04 | 江苏省疾病预防控制中心(江苏省公共卫生研究院) | Leukemia cell separation and extraction device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20190621 Termination date: 20191023 |