CN208725936U - A kind of animal eyes ball fixing device for photoacoustic imaging system - Google Patents
A kind of animal eyes ball fixing device for photoacoustic imaging system Download PDFInfo
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- CN208725936U CN208725936U CN201721356568.2U CN201721356568U CN208725936U CN 208725936 U CN208725936 U CN 208725936U CN 201721356568 U CN201721356568 U CN 201721356568U CN 208725936 U CN208725936 U CN 208725936U
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- animal
- pressing plate
- imaging system
- fixing device
- photoacoustic imaging
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Abstract
The utility model embodiment is suitable for technical field of photoacoustic, provides a kind of animal eyes ball fixing device for photoacoustic imaging system.The animal eyes ball fixing device includes pedestal, adjusts fixation kit and pressing plate, fixation kit is adjusted to be mounted on the base, the both ends of pressing plate, which are fixed on, to be adjusted on fixation kit, there is the accommodation space for clamping animal head between pressing plate and pedestal, at least one is offered in the middle part of pressing plate for being arranged the through-hole of animal eyeball.The utility model convenient and efficient can carry out noninvasive fixation to animal eyeball by the through-hole on pressing plate, animal breath and Rotation of eyeball are effectively eliminated to imaging bring adverse effect, make photoacoustic imaging system more precise sharpness, and animal eyeball blood vessel and its disease can be observed steadily in the long term.
Description
Technical field
The utility model belongs to technical field of photoacoustic more particularly to a kind of animal eyeball for photoacoustic imaging system
Fixed device.
Background technique
Photoacoustic imaging is a kind of a kind of breakthrough Novel noninvasive biomedical imaging for having both optics Yu ultrasonic imaging advantage
Technology, principle are that pulse laser is imported into biological tissue, and tissue passes through detection because transient thermal growths generate ultrasonic signal
This signal obtains the light absorption information of tissue, to provide the contrast mechanism based on optical absorption characteristics for imaging.In biological tissue
Hemoglobin is different to the degree of absorption of different wavelengths of light, and the photoacoustic signal degree of strength being inspired is also different, and selection is high
The Single wavelength of absorption is scanned blood vessel, can direct imaging, without injecting any contrast medium；And multi-wavelength is selected to be swept
It retouches, then can obtain the parameters such as oxygen saturation, oxygen metabolism rate in blood by calculating, this is to research Tumor Angiongesis and research and development
Anticancer drug has great significance.
Since ultrasonic wave is decayed very greatly in air, in order to detect the ultrasonic signal of generation, in biological tissue and probe
Between must have couplant (usually water or medical ultrasonic coupling agent), usually ultrasonic probe is placed in sink, sink bottom
Biological sample surface is applied and is tightly attached on optical thin film after spreading couplant by lower aperture and layer overlay optical thin film.Work as pulse
Laser is imported into biological tissue inspire ultrasonic wave after, ultrasonic signal is spread out of from tissue, by couplant, film and water,
Finally received by ultrasonic probe.
In the optoacoustic system of current non-array formula, limited by ultrasonic probe quantity and mechanical scanning speed, when it is to one
A large area needs the long period when being imaged, therefore it is required that testee remain stationary state as far as possible during scanning.Optoacoustic
System at present can to mouse ear blood vessel, go the cerebral vessels of epidermis to carry out blur-free imaging, but for rat anterior ocular segment blood
Pipe always can not blur-free imaging, the reason is that animal breath movement influences its trunk entirety undulatory motion, the measured object in movement
Body be easy to cause imaging artefacts.And generally use the fixed animal eyeballs of a large amount of adhesive tapes at present, the fixed form there are many drawbacks,
It is too loose to cause larger shake if fixation tightly will cause very much its ischemic, experiment generally require by repeatedly it is fixed can be only achieved compared with
Good fixed effect, and even if fixing successfully, which also can not be by steadily long-term observation.
Utility model content
The utility model embodiment technical problem to be solved is to provide a kind of animal for photoacoustic imaging system
Eyeball fixture, it is intended to solve present in animal eyeball fixed form in the prior art fixed inconvenient and animal breath and
Rotation of eyeball causes the problem of imaging artefacts.
The utility model embodiment, which is achieved in that, provides a kind of fixed dress of the animal eyeball for photoacoustic imaging system
It sets comprising pedestal, adjusting fixation kit and pressing plate, the adjusting fixation kit are mounted on the base, the pressing plate
Both ends be fixed on the adjusting fixation kit, there is appearance for clamping animal head between the pressing plate and the pedestal
It receives space, at least one is offered in the middle part of the pressing plate for being arranged through-hole of animal eyeball.
Further, the pressing plate is plastic plate or plank.
Further, the through-hole has several, and the size of each through-hole differs.
Further, the through-hole is circular hole.
Further, rubber ring is equipped on the through-hole.
Further, the outer peripheral edge of the rubber ring has groove, and the groove is removably connected in the through-hole
On inner wall.
Further, the adjusting fixation kit includes fixed block, briquetting and screw；It successively wears one end of the screw
The briquetting, pressing plate and fixed block are crossed, and is anchored on the pedestal.
Further, the screw is butterfly screws.
Further, the both ends of the pressing plate offer U-type groove, and the butterfly screws are threaded through in the U-type groove.
Further, the material of the briquetting and fixed block is metal.
Compared with prior art, beneficial effect is the utility model embodiment: the utility model is dynamic by what will be anaesthetized
Object is placed on pedestal, and its head is clamped between pressing plate and pedestal, while by the pressure of pressing plate, make animal eyeball by
Belling carries out noninvasive fixation to animal eyeball so as to convenient and efficient, effectively eliminates animal breath in the through-hole of pressing plate
With Rotation of eyeball to imaging bring adverse effect, make photoacoustic imaging system more precise sharpness, and can observe steadily in the long term dynamic
Object eyeball blood vessel and its disease.
Detailed description of the invention
Fig. 1 is that the animal eyeball fixture structure provided by the embodiment of the utility model for photoacoustic imaging system is illustrated
Figure；
Fig. 2 is animal eyes ball fixing device decomposition texture schematic diagram shown in FIG. 1；
Fig. 3 is the pressure plate structure schematic diagram in Fig. 1；
Fig. 4 is the rubber ring structural schematic diagram in Fig. 1；
Fig. 5 is the working state schematic representation of animal eyes ball fixing device shown in FIG. 1.
Specific embodiment
In order to make the purpose of the utility model, technical solutions and advantages more clearly understood, below in conjunction with attached drawing and implementation
Example, the present invention will be further described in detail.It should be appreciated that specific embodiment described herein is only used to explain
The utility model is not used to limit the utility model.
It as shown in Figures 1 to 5, is a kind of animal eyeball for photoacoustic imaging system provided by the embodiment of the utility model
Fixed device.The animal eyes ball fixing device includes 1, two adjusting fixation kit 2 of pedestal and pressing plate 3, and two adjustings are fixed
Component 2 is mounted on pedestal 1, and is oppositely arranged, and pressing plate 3 is located between two adjusting fixation kits 2, and both ends are fixed respectively
There is the accommodation space for clamping animal head, pressing plate 3 and pedestal 1 on adjusting fixation kit 2, between pressing plate 3 and pedestal 1
The distance between can by adjust fixation kit 2 height be adjusted.At least one is offered for covering at the middle part of pressing plate 3
If the through-hole 30 of animal eyeball, when so that animal head being pressed on pedestal 1 by pressing plate 3, animal eyeball is directed at through-hole 30, thus
Animal eyeball is protruded from through-hole 30.In the present embodiment, through-hole 30 is circular hole, and has several, each through-hole 30
Size differ, to adapt to be arranged the fixation of different size of animal eyeball respectively.
In above-mentioned implementation, rubber ring 4 is equipped on through-hole 30, specifically, the outer peripheral edge of rubber ring 4 has groove 40,
Groove 40 is removably connected on the inner wall of through-hole 30, to increase the elasticity and flexibility of 30 position of through-hole on pressing plate 3, is avoided
Animal eyeball is crushed, and the frictional force of clamping animal head can be enhanced.
In above-described embodiment, adjusting fixation kit 2 includes fixed block 21, briquetting 22 and screw 23.One end of screw 23
Briquetting 22, pressing plate 3 and fixed block 21 are sequentially passed through, and is connected through a screw thread and is anchored on pedestal 1, makes the equal energy in the both ends of pressing plate 3
It is enough locked between fixed block 21 and briquetting 22.In the present embodiment, which is butterfly screws, convenient for locking and pine
Pressing plate 3 is opened, and can be according to the size of animal head, by suitably adjusting butterfly screws, so as to the elastic of pressing plate 3
Degree is adjusted, and on the one hand can stablize and push down animal head, on the other hand will not transition compression lead to eyeball ischemic and shadow
Ring photoacoustic imaging effect.
In above-described embodiment, the material of briquetting 22 and fixed block 21 is metal, and pressing plate 3 is plastic plate or plank.At this
Briquetting 22 and fixed block 21 in embodiment use piece of stainless steel, and pressing plate 3 uses plastic plate, and the material of the plastic plate is using durable
PC (Polycarbonate polycarbonate) plastics, with certain elasticity, and to be colorless and transparent, in order to 3 energy of pressing plate
Enough stablize pushes down animal head, and can be easily by animal eyeball alignment belling in the through-hole 30 on pressing plate 3, with right
Animal eyeball is fixed.U-type groove 31 is offered at the both ends of pressing plate 3, butterfly screws 23 are threaded through in U-type groove 31, make to press
Plate 3 can be adjusted suitably in its longitudinal direction, be directed at animal eyeball convenient for the through-hole 30 on pressing plate 3.
In conclusion the animal eyes ball fixing device for photoacoustic imaging system of the utility model can be convenient it is fixed
Animal eyeball, eyes are shaken caused by effectively eliminating because of animal breath influences to photoacoustic imaging bring, makes photoacoustic imaging system more
Precise sharpness and observation animal eyeball blood vessel and its disease steadily in the long term, and animal survival and its eye after experiment
Ball does not have any wound；Meanwhile the animal eyeball is fixed on the fixation device by noninvasive, top is without other any machinery
Part blocks, and provides enough spaces for optoacoustic system imaging probe, is conducive to high-resolution and pops one's head in close to imaging position.This is practical
Novel animal eyes ball fixing device is applicable not only to the fixation of the animal eyeballs such as rat, rabbit, sees convenient for photoacoustic imaging system
Survey imaging, moreover it is possible to suitable for observation imaging is fixed to animal brain.
The above is only the preferred embodiment of the utility model only, is not intended to limit the utility model, all at this
Made any modifications, equivalent replacements, and improvements etc., should be included in the utility model within the spirit and principle of utility model
Protection scope within.
Claims (10)
1. a kind of animal eyes ball fixing device for photoacoustic imaging system, which is characterized in that including pedestal, adjust fixation kit
And pressing plate, the adjusting fixation kit are mounted on the base, the both ends of the pressing plate are fixed on the fixed group of the adjusting
There is the accommodation space for clamping animal head on part, between the pressing plate and the pedestal, opened up in the middle part of the pressing plate
There is at least one for being arranged the through-hole of animal eyeball.
2. being used for the animal eyes ball fixing device of photoacoustic imaging system as described in claim 1, which is characterized in that the pressing plate
For plastic plate or plank.
3. being used for the animal eyes ball fixing device of photoacoustic imaging system as described in claim 1, which is characterized in that the through-hole
With several, the size of each through-hole is differed.
4. being used for the animal eyes ball fixing device of photoacoustic imaging system as described in claim 1, which is characterized in that the through-hole
For circular hole.
5. being used for the animal eyes ball fixing device of photoacoustic imaging system as described in claim 1, which is characterized in that the through-hole
It is upper to be equipped with rubber ring.
6. being used for the animal eyes ball fixing device of photoacoustic imaging system as claimed in claim 5, which is characterized in that the rubber
The outer peripheral edge of ring has groove, and the groove is removably connected on the inner wall of the through-hole.
7. the animal eyes ball fixing device for photoacoustic imaging system as described in any one of claim 1 to 6, feature
It is, the adjusting fixation kit includes fixed block, briquetting and screw；One end of the screw sequentially pass through the briquetting,
Pressing plate and fixed block, and be anchored on the pedestal.
8. being used for the animal eyes ball fixing device of photoacoustic imaging system as claimed in claim 7, which is characterized in that the screw
For butterfly screws.
9. being used for the animal eyes ball fixing device of photoacoustic imaging system as claimed in claim 8, which is characterized in that the pressing plate
Both ends offer U-type groove, the butterfly screws are threaded through in the U-type groove.
10. being used for the animal eyes ball fixing device of photoacoustic imaging system as claimed in claim 7, which is characterized in that the pressure
The material of block and fixed block is metal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721356568.2U CN208725936U (en) | 2017-10-19 | 2017-10-19 | A kind of animal eyes ball fixing device for photoacoustic imaging system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721356568.2U CN208725936U (en) | 2017-10-19 | 2017-10-19 | A kind of animal eyes ball fixing device for photoacoustic imaging system |
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| CN208725936U true CN208725936U (en) | 2019-04-12 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107802372A (en) * | 2017-10-19 | 2018-03-16 | 中国科学院深圳先进技术研究院 | A kind of animal eyeball fixing device for photoacoustic imaging system |
-
2017
- 2017-10-19 CN CN201721356568.2U patent/CN208725936U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107802372A (en) * | 2017-10-19 | 2018-03-16 | 中国科学院深圳先进技术研究院 | A kind of animal eyeball fixing device for photoacoustic imaging system |
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