CN208626434U - The positioning device of personalized transcranial magnetic stimulation treatment based on 3D printing - Google Patents
The positioning device of personalized transcranial magnetic stimulation treatment based on 3D printing Download PDFInfo
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- CN208626434U CN208626434U CN201820140849.2U CN201820140849U CN208626434U CN 208626434 U CN208626434 U CN 208626434U CN 201820140849 U CN201820140849 U CN 201820140849U CN 208626434 U CN208626434 U CN 208626434U
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Abstract
The positioning device of the utility model discloses a kind of personalized transcranial magnetic stimulation treatment based on 3D printing, headgear including 3D printing and the electromagnetic coil positioning element on the headgear, the headgear is printed according to the brain structure and function image data of patients head, is divided into 2-3.5mm between the headgear and patient's scalp；The groove that the electromagnetic coil positioning element is equipped with and coil shape is adapted, so that coil field stimulation and the treatment region of preoperative doctor plan are overlapped.The utility model allows doctor quickly and correctly to find the stimulation location of plan in patients head, and carries out precise positioning to coil, to improve the accuracy of transcranial magnetic stimulation treatment, improves therapeutic effect；Utility model device is easy to operate, low manufacture cost, can easily implement personalized therapeutic scheme to different diseases, different patients.
Description
Technical field
The utility model relates to field of medical technology more particularly to a kind of personalized transcranial magnetic stimulation based on 3D printing to control
The positioning device for the treatment of is used for brain function research, the treatment of nerve and mental disease.
Background technique
Mental disease is a complex set of brain dysfunction, and clinical drug therapy effect is not satisfactory, all the time people
All alleviate the pain of patient in the measure for continuously attempting to some non-drug therapies.
Repetitive transcranial magnetic stimulation is a kind of electrodeless stimulation form, and magnetic stimulator is by storage capacitor (power supply), solid-state switch
It is formed with coil.When Neural stem cell, capacitor generates current impulse to coil discharge, and coil current can produce transient magnetic field and act on
In brain tissue, the induced current that magnetic field pulse induces in brain tissue sexually revises the excitement of nerve cell, play it is excited or
Inhibit the effect of neuron activity.Repetitive transcranial magnetic stimulation can make the excitability of cortex that change in long term occur, thus have and control
Treatment effect.
A kind of repetitive transcranial magnetic stimulation, as non-drug therapy means, it has also become the new treatment work of one kind of mental disease
Tool, especially its effect in terms for the treatment of depression, have been obtained extensive approval.
In practical applications, maximum problem is how to be accurately determined stimulation target spot to transcranial magnetic stimulation.Initially, target is stimulated
The selection at point position relies primarily on the anatomical knowledge that operator has, and is carried out substantially according to the distribution of human brain routine brain function
It determines.However, usually there is large error between the position of this generally determining stimulation point and actually active stimulation.For solution
The certainly above problem, existing localization method have:
1) navigator fix, since navigation equipment is expensive, the setting time of equipment is longer, and operation is comparatively laborious, popularizes
Property is poor.
2) electromagnetic coil headgear is to carry out Neural stem cell to entire scalp, therefore cannot be to different diseases, different patients
It treats with a certain discrimination, the therapeutic scheme of individual cannot be formed.
3) positioning cap, since everyone area of bed is different, the actual area in region and human brain on be labeled in cap
Domain deviation is very big, it cannot be guaranteed that the effect for the treatment of.
4) head measurement searches out required stimulated zone according to biological characteristic with ruler.This method is to be based on
What the experience of doctor was come, human factor is very big, so precision cannot be guaranteed.
Chinese utility model patent application CN201610832583.3 disclose it is a kind of based on magnetic resonance imaging through cranium magnetic
Stimulating coil localization method.Stimulation target spot is mapped into scalp on image, a stimulated zone is determined on scalp, then suffering from
The position of the stimulated zone is probably estimated on person head, places coil according to the position.It is practical not still to be accurately realized stimulation
The coincidence of position and planning location positions the mapping position of stimulated zone and places two steps of coil and still deposits in patients head
In subjective factor, precision be cannot be guaranteed.
Therefore, need to research and develop the new positioning device through cranium stimulation therapy of one kind to solve the above problems.
Utility model content
In order to solve the above technical problems, the utility model proposes a kind of, and the personalization based on 3D printing is pierced through cranium magnetic
Swash the positioning device for the treatment of, so that doctor can quickly and correctly find stimulation location on the head of people, and to coil into
Row precise positioning, to improve transcranial magnetic stimulation treatment effect.
In order to solve the above technical problems, the utility model adopts the following technical solution:
In the one side of the utility model, a kind of positioning dress of personalized transcranial magnetic stimulation treatment based on 3D printing is provided
It sets, the headgear including 3D printing and the electromagnetic coil positioning element on the headgear, which is the brain according to patients head
Structure and function image data prints, and is divided into 2-3.5mm between the headgear and patient's scalp；The electromagnetic coil positioning
The groove that component is equipped with and coil shape is adapted.
The brain structure and function image data includes MRI(Magnetic resonance imaging) data, fMRI(function nuclear magnetic resonance at
Picture) data, DTI(diffusion tensor) data, PET(positron emission computerized tomography) the image scans data such as data.
As the preferred technical solution of the utility model, the electromagnetic coil positioning element includes coil contact face and connection
Column, coil contact face connect headgear by connecting column, and the groove that coil contact face is equipped with and coil shape is adapted is for solid
Alignment circle, so that coil field stimulation and the treatment region of preoperative doctor plan are overlapped.
As the preferred technical solution of the utility model, the headgear with a thickness of 2-3.5mm.
As the preferred technical solution of the utility model, the coil connects transcranial magnetic stimulation instrument by connecting line.
Compared with prior art, the utility model has the following beneficial effects:
1) the exclusive positioning system of patient can be designed according to the different demands of each patient, it can be to different diseases
Sick, different patients treat with a certain discrimination, form personalized targeted treatment schemes.And it can extremely accurate realize a plan and control
Treatment region is overlapped with stimulated zone.
2) since the headgear is printed according to the actual size of patient, so compared with the cooperation between patient
It is good, it is positioned with the profile on head, will not be moved left and right in the treatment, can guarantee the effect for the treatment of.
3) cost of 3D printing is not high, and may be reused, and reduces costs.
4) time that doctor finds stimulation location dropped to zero (do not need doctor and manually find stimulation location) from 30 minutes, greatly
Efficiency is improved greatly, and improves the accuracy of stimulation location positioning.
5) as long as some preliminary trainings of doctor operate, the time of training is saved, operating procedure is simplified.
6) positioning accuracy for improving coil facilitates doctor and preferably studies influence of the different zones to different syndromes,
Facilitate the use scope of expansion magnetic stimulation treatment.
Detailed description of the invention
The present invention will be further described with reference to the accompanying drawings and examples.
Fig. 1 is that the headgear of the positioning device of personalized transcranial magnetic stimulation treatment of the utility model based on 3D printing is faced
Figure.
Fig. 2 is the wearing of the headgear of the positioning device of personalized transcranial magnetic stimulation treatment of the utility model based on 3D printing
Front view.
Fig. 3 is the vertical view of the headgear of the positioning device of personalized transcranial magnetic stimulation treatment of the utility model based on 3D printing
Figure.
Fig. 4 is the construction method of the positioning device of personalized transcranial magnetic stimulation treatment of the utility model based on 3D printing
Flow chart.
The reference numerals are as follows in figure:
1 is headgear, and 2 be coil contact face, and 3 be connecting column, and 4 be coil, and 5 be connecting line.
Specific embodiment
The utility model is described in further detail presently in connection with attached drawing.These attached drawings are simplified schematic diagram,
Only illustrate the basic structure of the utility model in a schematic way, therefore it only shows composition related with the utility model.
The technical solution that the utility model is proposed is as follows:
As shown in Figure 1-3, the utility model proposes a kind of personalized transcranial magnetic stimulation treatment based on 3D printing is determined
Position device, the 3D headgear 1 that the device mainly includes one to print according to the brain structure and function image data of patients head
With the electromagnetic coil positioning element being located on the headgear 1, which includes coil contact face 2 and connecting column 3,
Coil contact face 2 connects headgear 1 by connecting column 3, and the groove that coil contact face 2 is equipped with and 4 shape of coil is adapted is used for
Fixed coil 4, so that 4 field stimulation of coil and the treatment region of preoperative doctor plan are overlapped.It is recessed set by coil contact face 2
Slot can be adjusted matching according to the concrete shape size of coil 4, it is therefore an objective to which being placed on coil 4 can on coil contact face 2
Landing is not moved with fixation.Coil 4 connects transcranial magnetic stimulation instrument by connecting line 5.It can piercing through cranium magnetic according to any brand
The size shape for swashing the field stimulation of instrument and the practical 3D shape setting coil contact face 2 of coil 4, formulates personalized treatment
Scheme.
The headgear 1 is printed according to the brain structure and function image data of each patient head, the headgear 1 and trouble
The interval appropriateness of person's scalp, doctor can arbitrarily be adjusted to not only comfortable wearing according to patient's actual conditions but also can consolidate fixation when planning
Distance, the spacing distance be 2-3.5mm.Headgear 1 with a thickness of 2-3.5mm.
The profile on the head of headgear 1 positions, and will not move left and right in the treatment.
Coil contact face 2 on the headgear 1 is the specific stimulated zone according to specified by the illness of patient.
As shown in figure 4, the building of the positioning device of personalized transcranial magnetic stimulation treatment of the utility model based on 3D printing
Method, including following operating procedure:
The first step, patient carry out image scan (according to the actual situation, image scan can be MRI, fMRI, PET etc.), obtain
To head scanning imagery picture (i.e. DICOM image), the image by network or other media be input to client terminal (doctor's
Computer or mobile phone) surgical planning software；Preoperative planning software can carry out three-dimensional reconstruction to the image data of patient, according to brain
Table 3-D image formulates treatment region, and combines the true form and stimulated zone of particular brand electromagnetic coil, determines electromagnetic wire
The relative position of circle and patients head, and the three-dimensional data for exporting the positioning device is printed.
Second step carries out reconstructing three-dimensional model to patient image, such as brain table structure figure；
Third step determines thorn corresponding to patient condition according to the reconstructing three-dimensional model figure and medical treatment experience of patient
Swash region；Stimulated zone corresponding to the determining patient condition specifically: according to reconstructing three-dimensional model figure directly in three-dimensional mould
Stimulated zone is marked in type；Or stimulated zone is optimized and is corrected using following step:
1) area-of-interest in every DICOM image can be delineated for the accuracy of raising plan；
2) region delineated is split；
3) reconstructing three-dimensional model is carried out to the stimulated zone after segmentation, indicates different colors, or sit in conjunction with MNI
(MNI coordinate system or Talairach coordinate system are to scan several Normal Human Brains for mark system or Talairach coordinate system
Obtained standard brain map), or the intelligent operation based on big data is carried out again, it can also be in conjunction with magneticencephalogram etc. to stimulated zone
It is modified.
In third step, when selecting different stimulated zones to different diseases, the position of the coil of plan is made accordingly
Change.Such as melancholia, stimulated zone is generally left side forehead back lateral cortex and right side forehead carries on the back lateral cortex.
4th step, the sphere of action of planned stimulated zone and coil calculate the opposite position of coil and patients head
It sets, to ensure that stimulated zone is consistent with plan；
5th step, three-dimensional reconstruction scalp surface consider patient's hair amount and capitiform, determine suitable offset of the headgear relative to scalp
Distance (2-3.5mm, preferably 3mm), to obtain headgear contoured surface；
6th step, according to coil true form, places electromagnetism in the coil position of plan on the basis of the contoured surface of headgear
Coil positioning element keeps the groove location on electromagnetic coil positioning element consistent with the coil position of plan, to guarantee coil
Stimulated zone is overlapped with plan stimulated zone；The coil position in plan places electromagnetic coil positioning element, specifically: first
Coil contact face is placed, then connects coil contact surface and headgear with connecting column, connecting column and coil contact face form electromagnetic coil
Positioning element.
7th step, export headgear and electromagnetic coil positioning element threedimensional model, and print (headgear with a thickness of 2-
3.5mm)。
The headgear makes coil precise positioning, and is overlapped coil stimulation focus and specified stimulation point.To patient with top
Set, fixed coil realize magnetic stimulation treatment with transcranial magnetic stimulation instrument.The headgear is 2-3.5mm at a distance from scalp, even if so as to
It can also be treated on the basis of retaining patient's hair.Since the headgear is printed according to the actual size of patient
, so the cooperation between patient is relatively good.It is positioned with the biological characteristic of head part.There is determining for coil on headgear simultaneously
Position device, so that coil stimulation focus and specified stimulation point are overlapped.
It is enlightenment, through the above description, related work people with the above-mentioned desirable embodiment according to the utility model
Member can carry out various changes and amendments in the range of without departing from this item utility model technical idea completely.This item is real
It is not limited to the contents of the specification with novel technical scope, it is necessary to its technology is determined according to scope of the claims
Property range.
Claims (4)
1. a kind of positioning device of the personalized transcranial magnetic stimulation treatment based on 3D printing, which is characterized in that including 3D printing
Headgear and the electromagnetic coil positioning element on the headgear, the headgear are the brain structure and function image numbers according to patients head
According to what is printed, 2-3.5mm is divided between the headgear and patient's scalp；The electromagnetic coil positioning element is equipped with and coil
The adaptable groove of shape.
2. device as described in claim 1, which is characterized in that the electromagnetic coil positioning element includes coil contact face and company
Column is connect, coil contact face connects headgear by connecting column, and the groove that coil contact face is equipped with and coil shape is adapted is used for
Fixed coil, so that coil field stimulation and the treatment region of preoperative doctor plan are overlapped.
3. device as described in claim 1, which is characterized in that the headgear with a thickness of 2-3.5mm.
4. device as claimed in claim 1 or 2, which is characterized in that the coil connects transcranial magnetic stimulation instrument by connecting line.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201820140849.2U CN208626434U (en) | 2018-01-29 | 2018-01-29 | The positioning device of personalized transcranial magnetic stimulation treatment based on 3D printing |
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| CN201820140849.2U CN208626434U (en) | 2018-01-29 | 2018-01-29 | The positioning device of personalized transcranial magnetic stimulation treatment based on 3D printing |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108042918A (en) * | 2018-01-29 | 2018-05-18 | 上海理禾医疗技术有限公司 | The positioner and method of personalized transcranial magnetic stimulation treatment based on 3D printing |
| CN110192920A (en) * | 2019-06-19 | 2019-09-03 | 雅客智慧（北京）科技有限公司 | A kind of operating robot |
| CN110491669A (en) * | 2019-06-07 | 2019-11-22 | 中国医学科学院生物医学工程研究所 | A kind of H-type coil winding and fixed device and its application method |
-
2018
- 2018-01-29 CN CN201820140849.2U patent/CN208626434U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108042918A (en) * | 2018-01-29 | 2018-05-18 | 上海理禾医疗技术有限公司 | The positioner and method of personalized transcranial magnetic stimulation treatment based on 3D printing |
| CN110491669A (en) * | 2019-06-07 | 2019-11-22 | 中国医学科学院生物医学工程研究所 | A kind of H-type coil winding and fixed device and its application method |
| CN110491669B (en) * | 2019-06-07 | 2021-08-10 | 中国医学科学院生物医学工程研究所 | H-shaped coil winding and fixing device and using method thereof |
| CN110192920A (en) * | 2019-06-19 | 2019-09-03 | 雅客智慧（北京）科技有限公司 | A kind of operating robot |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Suzhou Lihe Medical Technology Co., Ltd. Assignor: Shanghai Lihe Medical Technology Co., Ltd. Contract record no.: X2019310000003 Denomination of utility model: Individualized transcranial magnetic stimulation positioning apparatus and method based on 3D printing Granted publication date: 20190322 License type: Exclusive License Record date: 20190819 |
|
| EE01 | Entry into force of recordation of patent licensing contract |