A kind of alimentary canal membrane tube of antibacterial
Technical field
The utility model relates to the field of medical instrument technology, especially it is a kind of for treat endocrine system disease (such as diabetes,
Islet function disorder, obesity etc.) or disease of lower digestive tract (such as inflammation) antibacterial alimentary canal membrane tube.
Background technique
It is known that diabetes are a kind of diseases being gradually valued by the people in recent years, it is one of rich people's disease, is source
It is continuously improved in the living standard of modern civilization society, after people's lives are rich, eat good things, eats smart, overnutrition, activity
Amount is reduced, thus the non-infectious epidemic disease generated, specifically, diabetes refer to the metabolic disease characterized by hyperglycemia
Disease.It is since defect of insulin secretion or its biological effect are impaired, or both have concurrently caused by.Diabetes can cause various
Tissue, especially eye, kidney, heart, blood vessel, the chronic lesion of nerve, dysfunction.Diabetes are usually along with fat and very
More complication cause greatly to threaten to people's health.Data are shown, only Chinese, in 20 years old or more adult, glycosuria
The disease incidence of disease is 9.7%, population about 1.5 hundred million of falling ill.It is known that it is to keep on a diet that common obesity and diabetes, which improve mode,
Increase movement, and assist certain drug therapy, this needs adhering to for a long time for patient, and once stops diet control and movement
After easily cause repeatedly and weight gain, the use of long-term drug or insulin also brings heavy financial burden to patient
With the inconvenience of life.
Another cure is Gastric bypass, is had very using Gastric bypass for radical cure type-II diabetes and improvement obesity
Good effect, in 2001, formal recommendation was metabolized surgical operation (including the operation of stomach turn of tidal stream) conduct to International Diabetes Federation
Obesity merges the treatment method of type-II diabetes, however Gastric bypass can cause wound to human body as a kind of surgical operation, because
This with many risks such as: death, intestinal obstruction, anastomotic leakage, pulmonary embolism, deep vein thrombosis, injury of portal vein, respiratory system
Deng.
The patent document of Publication No. CN106923944A discloses a kind of enteron aisle isolation membrane tube release, including tubular shell
Body, shell one end have the first opening, and it further includes setting that the other end, which has the second opening, membrane tube to be released is arranged in shell,
In first opening and the releaser that is connect with described membrane tube one end, by the material that can be digested and assimilated by human body intestinal canal
It is made;The inner tube, the tube and the outer tube of relative motion are successively arranged and are capable of between each other, inner tube a part is located in shell simultaneously
It is connect with releaser, one end of the central tube fixed sleeves are equipped with the block piston being located in shell, and outer tube is located at outside shell and one end
It is fixedly connected in the second opening;Operation inner tube and middle pipe make the two axially movable, and releaser and shell disengage, and membrane tube is de-
Shell out, and discharged in the designated position of human body intestinal canal.Structure is simple, and manufacturing cost is low, easy to operate, highly reliable, implantation
Wound will not be generated when human body, had no toxic and side effect to human body.
The above-mentioned gastral membrane tube of implantation, for treating endocrine system disease, such as in treatment and reverting diabetes, islet function
Disorder, fat weight-reducing etc. or disease of lower digestive tract, if inflammation etc. achieves very good effect, but it has also been found that
A small amount of complication, such as hepatapostema is exactly a relatively serious complication, it is revolutionary which also limits this
The extensive clinical application of product.
Summary of the invention
In order to solve the above technical problems, it the purpose of the utility model is to provide a kind of alimentary canal membrane tube of antibacterial, adopts
Conduit is isolated in the alimentary canal made of anti-biotic material, using the form of segmentation antibacterial, mainly in duodenofiberscope bacterium ratio
It is added to anti-biotic material compared with collection middle section, can not only play relatively good fungistatic effect in this way, but also can be to avoid generation intestinal flora
The case where disorder.
Specifically, the utility model uses technical solution below:
A kind of alimentary canal membrane tube of antibacterial, including bracket (1) and membrane tube (2), which is characterized in that outside the membrane tube (2)
Diameter is 10mm to 35mm, and the wall thickness of the membrane tube (2) is that 0.001mm to 0.3mm, membrane tube (2) and bracket (1) pass through suture, heat
Pressure, ultrasonic bonding or laser welding are fixedly connected, and the membrane tube (2) is being equipped with outer surface by resisting with bracket (1) junction
Antibacterial section (3) made of bacterium material, antibacterial section (3) length are 2cm to 10cm, and the other positions of the membrane tube (2) are using non-anti-
Bacterium material is made.
The alimentary canal membrane tube can be implanted alimentary canal.The alimentary canal includes esophagus, Stomach duodenum, jejunum, ileum
Deng so that the different location of the implantable conduit can correspond respectively to esophagus, Stomach duodenum, jejunum, ileum etc..By
Have the function of in the conduit in different location it is different, so as to generate different effects to gastral different piece.It should
Alimentary canal membrane tube has the function of segmentation antibacterial, and the position where anti-biotic material is duodenofiberscope opening near sites, this
Sample, the length of the anti-biotic material are preferably 2-10cm, and suboptimum is selected as 2-8cm, most preferably 3-5cm.
The alimentary canal membrane tube can be made of high molecular material.The high molecular material must have good biology
Compatibility, can in human body prolonged stay, and not to human body generate adverse effect.Prolonged stay, which refers to, to stop in human body alimentary canal
It stays three months or the longer time.The high molecular material must be sufficiently flexible, will not generate to alimentary canal mucous membrane bad
Stimulation, patient will not generate sense of discomfort after the implantation, even if one or two people have slight discomfort, also can voluntarily disappear in a short time
It loses.The high molecular material must have good chemistry and biological stability, in the various strong acid and strong bases of alimentary canal and biological enzyme
Under the influence of, chemical change should not occur, generate the leachable unfavorable to human body.The high molecular material can be poly- second
Alkene, fluoropolymer, polyurethane, silica gel etc..The high molecular material must have good processing performance, can be processed into thin
Film or tubular film, the film thickness is in 0.01-0.1mm.
The anti-biotic material must have good biocompatibility, non-toxic to humans, environmentally friendly.Institute
The anti-biotic material stated must have apparent antibacterial inhibitory effect to pathogenic microorganisms, can keep antibiotic property in a long time
Energy.The anti-biotic material must have excellent physical property, there is certain intensity and flexibility in tissue.It is described
Anti-biotic material must have that itself clean is environmentally friendly, using convenient, be preferably provided with certain self-degradation ability.The antibacterial material
Material can be nano silver, Nanometer Copper, vanillic aldehyde, ethyl vanillin aldehydes chemical combination or chitosan etc..
Preferably, the membrane tube (2) is using curtain coating, squeezes out or be blow molded manufactured multi-layered composite pipe, the membrane tube (2)
Outer tube be divided into non-antibacterial section (22) made of antibacterial section (3) and non-anti-biotic material made of anti-biotic material.
Preferably, the antibacterial section (3) and non-antibacterial section (22) are compounded on same inner tube (21).
Preferably, the antibacterial section (3) is the antibacterial for coating anti-biotic material on the partial outer face of membrane tube (2) and being formed
Coating.
Preferably, the antibacterial section (3) is the antibacterial that composite antibacterial material is formed on the partial outer face of membrane tube (2)
Composite layer.
Preferably, the bracket (1) is the netted pipe being compiled by braided wires, the braided wires are to meet biofacies
The elastic yarn of capacitive can be wire, high molecular material silk either degradation material silk.
Preferably, the bracket includes bracket upper section and bracket lower section, bracket upper section outer diameter is bigger than bracket lower section by 5~
15mm。
Preferably, the bracket is equipped with developing ring or exhausting line.
The utility model is due to the technical solution more than using, and compared with prior art, can plant described in this patent
Conduit have certain antibacterial effect, can effectively avoid or reduce the generation of alimentary canal inflammation, such as hepatapostema, pancreatitis
Deng.And this patent is mainly compared collection middle section in duodenofiberscope bacterium and is added to antibacterial using the form of segmentation antibacterial
Material can not only play relatively good fungistatic effect in this way, but also can be to avoid there is a situation where enteric flora disturbances.And material used
Expect that structure is simple, manufacture craft is convenient, at low cost, speed of production is fast, quality is guaranteed and it is easily manufactured the advantages that, and plant
It is good to enter rear comfort, compliance, tissue will not be damaged.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the utility model;
Fig. 2 is the section view of the utility model embodiment 1;
Fig. 3 is the longitudinal sectional view (part) of the utility model embodiment 1;
Fig. 4 is the section view of the utility model embodiment 2;
Fig. 5 is the longitudinal sectional view (part) of the utility model embodiment 2;
Description of symbols:
The non-antibacterial section of 1- bracket 2- membrane tube 3- antibacterial section 21- inner tube 22-.
Specific embodiment
The embodiments of the present invention are described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning
Same or similar element or element with the same or similar functions are indicated to same or similar label eventually.Below by ginseng
The embodiment for examining attached drawing description is exemplary, it is intended to for explaining the utility model, and should not be understood as to the utility model
Limitation.
In the description of the present invention, it should be understood that term " center ", " longitudinal direction ", " transverse direction ", " length ", " width
Degree ", " thickness ", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom" "inner", " up time
The orientation or positional relationship of the instructions such as needle ", " counterclockwise " is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of
Describe the utility model and simplify description, rather than the device or element of indication or suggestion meaning must have a particular orientation,
It is constructed and operated in a specific orientation, therefore should not be understood as limiting the present invention.
In addition, term " first ", " second " are used for descriptive purposes only and cannot be understood as indicating or suggesting relative importance
Or implicitly indicate the quantity of indicated technical characteristic.Define " first " as a result, the feature of " second " can be expressed or
Implicitly include one or more of the features.In the description of the present invention, unless otherwise indicated, the meaning of " multiple "
It is two or more, unless otherwise restricted clearly.
In the present invention unless specifically defined or limited otherwise, term " installation ", " connected ", " connection ", " Gu
It is fixed " etc. terms shall be understood in a broad sense, for example, it may be being fixedly connected, may be a detachable connection, or be integrally connected;It can
To be mechanical connection, it is also possible to be electrically connected;It can be directly connected, can also can be indirectly connected through an intermediary
Connection inside two elements.For the ordinary skill in the art, above-mentioned term can be understood as the case may be
Concrete meaning in the present invention.
In the present invention unless specifically defined or limited otherwise, fisrt feature the "upper" of second feature or it
"lower" may include that the first and second features directly contact, and also may include that the first and second features are not direct contacts but lead to
Cross the other characterisation contact between them.Moreover, fisrt feature includes above the second feature " above ", " above " and " above "
One feature is right above second feature and oblique upper, or is merely representative of first feature horizontal height higher than second feature.First is special
Sign is directly below and diagonally below the second feature including fisrt feature under the second feature " below ", " below " and " below ", or only
Indicate that first feature horizontal height is less than second feature.
Embodiment 1:
A kind of alimentary canal membrane tube of antibacterial as shown in Figure 1, including bracket 1 and membrane tube 2, which is characterized in that the membrane tube 2
Outer diameter be 10mm to 35mm, the wall thickness of the membrane tube 2 be 0.001mm to 0.3mm, membrane tube 2 and bracket 1 by suture, hot pressing,
Ultrasonic bonding or laser welding are fixedly connected, and the membrane tube 2 is being equipped with outer surface by anti-biotic material system with 1 junction of bracket
At antibacterial section 3, which is 2cm to 10cm, and the other positions of the membrane tube 2 are made of non-anti-biotic material.
In the present embodiment, the membrane tube 2 is using curtain coating, squeezes out or be blow molded manufactured multi-layered composite pipe, such as Fig. 2, Fig. 3
Shown, the outer tube of the membrane tube 2 is divided into non-antibacterial section 22 made of antibacterial section 3 and non-anti-biotic material made of anti-biotic material.Institute
It states antibacterial section 3 and non-antibacterial section 22 is compounded in same inner tube 21.It is attached that the anti-biotic material section is in duodenofiberscope
Close position, the anti-biotic material can inhibit a large amount of growths of bacterium, so that avoid bacterium from driving in the wrong direction causes into choledochus
The generation of the complication such as pancreatitis, hepatapostema.
The bracket 1 is the netted pipe being compiled by braided wires, and the braided wires are to meet the elasticity of biocompatibility
Silk can be wire, high molecular material silk either degradation material silk.The bracket 1 includes under bracket upper section and bracket
Section, bracket upper section outer diameter are 5~15mm bigger than bracket lower section.The bracket 1 is equipped with developing ring or exhausting line.
Embodiment 2:
A kind of alimentary canal membrane tube of antibacterial as shown in Figure 3, Figure 4, the antibacterial section 3 are the partial outer faces in membrane tube 2
The antimicrobial coating that upper coating anti-biotic material is formed.Alternatively, the antibacterial section 3 is the composite antibacterial on the partial outer face of membrane tube 2
The antibacterial composite layer that material is formed.Antibiotic layer is set on the membrane tube material near duodenofiberscope, and antibiotic layer, which can be, to be received
One or more anti-biotic materials such as meter Yin, silver compound, chitosan.Other are same as Example 1.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is contained at least one embodiment or example of the utility model.In the present specification, to the schematic table of above-mentioned term
Stating may not refer to the same embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be
It can be combined in any suitable manner in any one or more embodiment or examples.
Although the embodiments of the present invention have been shown and described above, it is to be understood that above-described embodiment is
Illustratively, it should not be understood as limiting the present invention, those skilled in the art are not departing from the utility model
Principle and objective in the case where above-described embodiment can be changed in the scope of the utility model, modify, replace and
Modification.Within the spirit and principle of the utility model, any modification, equivalent replacement, improvement and so on should be included in
Within the protection scope of the utility model.