CN208313833U - A kind of dry type fluorescence immunity analyzer - Google Patents
A kind of dry type fluorescence immunity analyzer Download PDFInfo
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- CN208313833U CN208313833U CN201820786091.XU CN201820786091U CN208313833U CN 208313833 U CN208313833 U CN 208313833U CN 201820786091 U CN201820786091 U CN 201820786091U CN 208313833 U CN208313833 U CN 208313833U
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- transmission microscope
- type fluorescence
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Abstract
The utility model discloses a kind of dry type fluorescence immunity analyzers, including main body cover, master control borad and optical path mould group are installed in main body cover, optical path mould group includes transmission microscope base, laser source, mirror unit, control panel and slot, for diaphotoscope seat between slot and control panel, laser source is located at the side of transmission microscope base, and mirror unit is located at the top of slot, dichroic mirror is installed on transmission microscope base, reflecting optics are installed on mirror unit.Laser refracts to reflecting optics through dichroic mirror, it is reflexed on reagent strip through reflecting optics again, and reagent strip is excited to generate fluorescence signal, then fluorescence signal inversely to dichroic mirror and passes through dichroic mirror and is radiated on control panel along laser light incident path, and fluorescence signal is converted to electric signal and is sent to master control borad by control panel carries out processing operation.The utility model reduces the error of detection, improves the speed and sensitivity of detection, can be widely applied to fluoroimmunoassay technical field.
Description
Technical field
The utility model relates to fluoroimmunoassay technical field, in particular to a kind of dry type fluorescence immunity analyzer.
Background technique
Bedside test (Bedside test) starts from 20th century mid-term, nineteen fifty-seven, and Edmonds detects blood with the dry chemical scraps of paper
Dry chemical paper disk method detection project is expanded and is commercialized by sugar and glucose in urine, subsequent Ames company, since method is easy quickly, quickly
It is widely used.Thereafter, indirect hemagglutination test, latex test, immunity-chromatography test and biosensor technology etc. are easy, fast
The method of speed occurs in succession, receives the favor of patient, clinician and medicine testing staff.With computer technology and
The development of instrument technique, clinical laboratory technology have gradually changed traditional method of inspection, and new inspection technology is examining for disease
Disconnected analysis provides more quick, accurate method.Hommization, low cost and benefit are more focused in the design of Clinical Laboratory Instruments
In environmental protection.
Currently, the medical laboratory instrument product in the whole world is technically positive towards digitlization, networking, micromation direction hair
Exhibition, proposes the developing direction of laboratory instrument and equipment --- automation, intelligent, standardization, personalized and miniature portable.
Immunoassay (immunoassay, IA) is a kind of analytical technology reacted based on antigen and antibody characteristic.According to
The difference of labelling technique means, immunoassay be broadly divided into radiommunoassay, EIA enzyme immunoassay, chemiluminescence immune assay,
Fluoroimmunoassay etc..Detection speed is fast, measurement accuracy is accurate, operating method is simple and convenient by it for fluorescence immunity analyzer
Advantage has broad application prospects in clinical detection instrument.Fluorescence immunity analyzer cooperates corresponding test card to use, detection
Determinand content, the different detection projects suitable for samples such as blood, urines in sample.
Existing fluorescence immunity analyzer is due to geartrain components, and mostly bench device substantially is inconvenient to carry,
Detection time is longer, therefore can not be applied to the occasion of some temporary detectings, on ambulance.In addition, due to existing in system
Moving component vibrates caused error and the asynchronous caused calculating error of light source so that existing in whole system, affects inspection
The accuracy of survey.It is relatively high to the stability requirement of excitation light source and since the excitation of C, T line is asynchronous, lead to excitation light source
Rejection rate it is larger, instrument overall cost rise.
Utility model content
The technical problem to be solved by the utility model is to provide a kind of dry type fluorescence immunity analyzers, use a kind of more
Point while the quick optical path mould group read, can excite T, C line number evidence of reagent strip, while typing simultaneously, solve random error；And
Remove the transmission mechanism in Traditional photovoltaic mould group, reduce vibration and jitter error, to keep result more accurate reliable；In addition,
Due to parallel logging data, detects speed and also accelerate 10 times or more than traditional optical path mould group.
Used technical solution to solve above-mentioned technical problem:
A kind of dry type fluorescence immunity analyzer, including main body cover are equipped with master control borad and optical path in the main body cover
Mould group, the optical path mould group include transmiting microscope base, laser source, mirror unit, control panel and the slot for reagent strip insertion, institute
Diaphotoscope seat is stated between the slot and the control panel, the laser source is located at the side of the transmission microscope base, described
Mirror unit is located at the top of the slot, is equipped with dichroic mirror on the transmission microscope base, is equipped on the mirror unit anti-
Penetrate eyeglass.
Further, it is disposed with optical filtering through-hole in the transmission microscope base, being equipped in the optical filtering through-hole can focused light passages
Transmit microscope group, one end of the optical filtering through-hole is towards the mirror unit, and the other end of the optical filtering through-hole is towards the control
Plate, the dichroic mirror are uprightly arranged on the optical filtering through-hole towards one end of the mirror unit.
Further, the optical path mould group includes outer barcode scanner.
Further, the optical path mould group includes interior barcode scanner.
Further, inductor is disposed on the main body cover.
Further, optical filter is disposed in the optical filtering through-hole.
Further, display screen is disposed on the main body cover.
Further, the laser and the dichroiscopic mirror surface angle that the laser source projects are 45 °.
Further, the optical path mould group includes mould group bottom plate, the transmission microscope base, laser source, mirror unit, control panel and
Slot is arranged on the mould group bottom plate, and the angle of the reflecting optics and the mould group bottom plate is 45 °.
The utility model has the advantages that the utility model, which designs laser, refracts to reflecting optics through dichroic mirror, then reflexed to through reflecting optics
On reagent strip, and reagent strip is excited to generate fluorescence signal, then fluorescence signal inversely to dichroic mirror and is worn along laser light incident path
It crosses dichroic mirror to be radiated on control panel, fluorescence signal is converted to electric signal and is sent to master control borad by control panel carries out processing operation；
It designs outer barcode scanner and reads patient information, design interior barcode scanner reading reagent parameter information, design inductor is read
Take reagent strip parameter database information, and the database information pair that the information that interior barcode scanner is read and inductor are read
Than Corresponding matching.The utility model reduces the error of detection, improves the speed and sensitivity of detection, can be widely applied to
Fluoroimmunoassay technical field.
Detailed description of the invention
Fig. 1 is the outline drawing of the utility model；
Fig. 2 is the exploded view of the utility model；
Fig. 3 is the structure chart of photoelectricity mould group；
Fig. 4 is that photoelectricity mould group removes the main view after top cover；
Fig. 5 is the structure chart for reflecting microscope group；
Fig. 6 is the main sectional view of lens group；
Fig. 7 is the side view of Fig. 5.
Specific embodiment
The utility model is described further below with reference to Fig. 1 to Fig. 7.
A kind of dry type fluorescence immunity analyzer, including main body cover, the main body cover include main body upper casing 1 and main body bottom
Shell 2 is equipped with master control borad 4 and optical path mould group 7 in the main body cover.The optical path mould group 7 includes transmission microscope base 17, laser source
11, mirror unit 14, control panel 12 and the slot being inserted into for reagent strip 20.The transmission microscope base 17 is located at the slot and institute
It states between control panel 12, the mirror unit 14 is located at the top of the slot, is equipped with dichroic mirror on the transmission microscope base 17
18, reflecting optics 15 are installed on the mirror unit 14.Optical filtering through-hole is disposed in the transmission microscope base 17, described filter is led to
Be equipped in hole can focused light passages transmission microscope group.
It is the test sample for extracting from patient in reagent strip 20 in the present embodiment.
The test method of dry type fluorescence immunity analyzer is as follows: the laser that the laser source 11 issues is through the dichroic mirror 18
The reflecting optics 15 are refracted to, then are reflexed on the reagent strip 20 in slot through the reflecting optics 15, and excite reagent strip
20 generate fluorescence signal, and for fluorescence signal along laser light incident path inversely to the transmission microscope group, fluorescence signal passes through the transmission
Microscope group is penetrated on the control panel 12, and fluorescence signal is converted to electric signal by the control panel 12, and is sent to dry type fluorescence and is exempted from
The master control borad 4 of epidemic disease analyzer carries out processing operation.
In the present embodiment, the laser source 11 is "-" type light source, and the laser center wavelength of sending is 520nm, the control
Making sheet 12 is line array CCD control panel.The 18 refrangible laser of dichroic mirror, but have no effect on the incidence of fluorescence signal.
In the present embodiment, one end of the optical filtering through-hole is towards the mirror unit 14, the other end of the optical filtering through-hole
Towards the control panel 12, the dichroic mirror 18 is uprightly arranged on the optical filtering through-hole towards the one of the mirror unit 14
The axis angle of end, the mirror surface of the dichroic mirror 18 and the optical filtering through-hole is 45 °.18 refrangible of dichroic mirror is above-mentioned to swash
Light, but not reflect above-mentioned fluorescence signal, therefore above-mentioned fluorescence signal is directly through the dichroic mirror 18, using the transmission
The processing of microscope group, focusing illumination is on the control panel 12.In the present embodiment, to filter off the veiling glare in above-mentioned fluorescence signal,
It there also is provided optical filter in the light-filtering channels, by the processing of the optical filter, only retain the fluorescence that wave band is 570 and believe
Number.
The laser source 11 is located at the side of the transmission microscope base 17, the laser and two color that the laser source 11 projects
The angle of 18 mirror surface of mirror is 45 °.The reflecting optics 15 are tiltedly mounted on the mirror unit 14, the reflecting optics 15 with
The angle on 20 surface of reagent strip is 45 °.
In the present embodiment, the optical path mould group 7 includes mould group bottom plate, the transmission microscope base 17, laser source 11, mirror unit
14, control panel 12 and slot are arranged on the mould group bottom plate.The optical path mould group 7 further includes by mould group bottom case 13 and top cover
The module shell of 16 compositions, the mould group bottom plate are mounted in the module shell, and the mould group bottom case 13 and top cover 16 are adopted
It is made of light-proof material.Aforementioned reflecting optics 15 and the angle on 20 surface of reagent strip are 45 °, i.e., the described reflecting optics 15 and institute
The angle for stating mould group bottom plate is 45 °.
Be disposed on the main body cover can brush IC card inductor 5, the number of reagent strip information can be read by brush IC card
According to library, the optical path mould group 7 includes the interior barcode scanner 9 that 20 information of reagent strip being inserted into the slot can be read, and is passed through
The database information that the information that the interior barcode scanner 9 is read is read with the inductor 5 compares, it may be determined that the secondary insertion
The concrete model parameter of the reagent strip 20.The optical path mould group 7 further includes outer barcode scanner 10, can be used for reading reagent item
Patient's sample information on 20 is disposed with the opening stretched out for the outer barcode scanner 10 on the main body cover.It is above-mentioned
These information read are sent to the master control borad 4, and test result is obtained after handling operation, is arranged on the main body cover
There is display screen 3, test result can be shown on the display screen 3.The display screen 3 is touch screen.
It there also is provided power panel 6 in the main body cover.
Compared with traditional optical path modular structure, the utility model, which has the advantages that, has got rid of conventional light path mould group
In a whole set of drive mechanism, alleviate instruments weight, be conducive to instrument miniaturization and eliminate transmission parts operation when vibrate and tremble
The dynamic error introduced；Excitation light source uses "-" type light source, is radiated at after refraction and reflection on reagent strip 20, inspires simultaneously
The fluorescence signal of T line and C line on reagent strip 20, eliminates flashing and determines bring error and improve detection speed；It adopts
Guarantee the maximum reflection and reception of different-waveband laser with dichroic mirror；Transmission microscope group, which ensure that collect to greatest extent, to be had
Fluorescence signal, the line array CCD control panel of receiving end by fluorescence signal be converted into electric signal ensure that its detection speed and
Sensitivity.
The embodiments of the present invention is explained in detail in conjunction with attached drawing above, but the utility model is not limited to
State embodiment, within the scope of knowledge possessed by those of ordinary skill in the art, can also do not depart from it is practical
Various changes can be made under the premise of novel objective.
Claims (9)
1. a kind of dry type fluorescence immunity analyzer, it is characterised in that: including main body cover, be equipped with master control in the main body cover
Plate (4) and optical path mould group (7), the optical path mould group (7) include transmission microscope base (17), laser source (11), mirror unit (14), control
Making sheet (12) and the slot being inserted into for reagent strip (20), the transmission microscope base (17) are located at the slot and the control panel
(12) between, the laser source (11) is located at the side of transmission microscope base (17), and the mirror unit (14) is located at described insert
The top of slot is equipped with dichroic mirror (18) on the transmission microscope base (17), is equipped with reflecting optics on the mirror unit (14)
(15)。
2. a kind of dry type fluorescence immunity analyzer according to claim 1, it is characterised in that: in the transmission microscope base (17)
Be disposed with optical filtering through-hole, be equipped in the optical filtering through-hole can focused light passages transmission microscope group, one end court of the optical filtering through-hole
To the mirror unit (14), for the other end of the optical filtering through-hole towards the control panel (12), the dichroic mirror (18) is upright
It is arranged in one end on the optical filtering through-hole towards the mirror unit (14).
3. a kind of dry type fluorescence immunity analyzer according to claim 1, it is characterised in that: optical path mould group (7) packet
Include outer barcode scanner (10).
4. a kind of dry type fluorescence immunity analyzer according to claim 3, it is characterised in that: optical path mould group (7) packet
Include interior barcode scanner (9).
5. a kind of dry type fluorescence immunity analyzer according to claim 4, it is characterised in that: arranged on the main body cover
There are inductor (5).
6. a kind of dry type fluorescence immunity analyzer according to claim 2, it is characterised in that: arranged in the optical filtering through-hole
There is optical filter.
7. a kind of dry type fluorescence immunity analyzer according to claim 1, it is characterised in that: arranged on the main body cover
There are display screen (3).
8. a kind of dry type fluorescence immunity analyzer according to claim 1, it is characterised in that: the laser source (11) is projected
Laser and the mirror surface angle of the dichroic mirror (18) be 45 °.
9. a kind of dry type fluorescence immunity analyzer according to claim 1, it is characterised in that: optical path mould group (7) packet
Mould group bottom plate is included, the transmission microscope base (17), laser source (11), mirror unit (14), control panel (12) and slot are arranged in
On the mould group bottom plate, the angle of the reflecting optics (15) and the mould group bottom plate is 45 °.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820786091.XU CN208313833U (en) | 2018-05-24 | 2018-05-24 | A kind of dry type fluorescence immunity analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820786091.XU CN208313833U (en) | 2018-05-24 | 2018-05-24 | A kind of dry type fluorescence immunity analyzer |
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| Publication Number | Publication Date |
|---|---|
| CN208313833U true CN208313833U (en) | 2019-01-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201820786091.XU Active CN208313833U (en) | 2018-05-24 | 2018-05-24 | A kind of dry type fluorescence immunity analyzer |
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| CN (1) | CN208313833U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108828206A (en) * | 2018-05-24 | 2018-11-16 | 广州天宝颂原生物科技开发有限公司 | A kind of dry type fluorescence immunity analyzer and its test method |
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2018
- 2018-05-24 CN CN201820786091.XU patent/CN208313833U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108828206A (en) * | 2018-05-24 | 2018-11-16 | 广州天宝颂原生物科技开发有限公司 | A kind of dry type fluorescence immunity analyzer and its test method |
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