CN207832780U - Integrated form disintegration time limited tester calibration device based on optical correction - Google Patents
Integrated form disintegration time limited tester calibration device based on optical correction Download PDFInfo
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- CN207832780U CN207832780U CN201820093710.7U CN201820093710U CN207832780U CN 207832780 U CN207832780 U CN 207832780U CN 201820093710 U CN201820093710 U CN 201820093710U CN 207832780 U CN207832780 U CN 207832780U
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Abstract
The utility model proposes a kind of integrated form disintegration time limited tester calibration device based on optical correction, including optical-electric module, electronic counting module, temperature measurement module, range finder module and data processing module；The optical-electric module includes laser emitter, photoelectric detector and photoelectricity timing module, the side of the laser emitter direct projection constant temperature beaker, the photoelectric detector is arranged in the other side of constant temperature beaker, the temperature measurement module is arranged in constant temperature beaker, and the electronic counting module and range finder module are arranged on the hanging basket holder of disintegration tester；Install laser light source additional laser beam expander, expand the area of detection of light source, so that light source detection area Landfill covering is entirely disintegrated region, the case where avoiding causing erroneous judgement due to light beam process disintegration region, the science of medicine disintegration test, accurate calibration result are obtained.
Description
Technical field
The utility model is related to medicine disintegration technical field of measurement and test, more particularly to a kind of integrated form based on optical correction collapses
Solve time limit tester calibration device.
Background technology
Disintegration time limited tester is a kind of intellectualized detection instrument being widely used in the industries such as medicine, this kind of instrument is basis
《Pharmacopoeia of People's Republic of China》The electromechanical that (2000 editions) develop in relation to the regulation that the disintegration time limiteds such as tablet, pill are detected
Medicine inspection instrument, it show using point old character liquid crystal module, the control by SCM system implementation to the jacking system time, can be with
It is conveniently accomplished disintegration time limited detection, the time can be arbitrary preset.
2 months 2014, State General Administration for Quality Supervision issued JJF1449-2014《Disintegration time limited tester calibrating standard》, the rule
Model defines the main contents of disintegration time limited tester calibration for the first time, is provided for the measurement and calibration work of disintegration time limited tester
Very important technical basis.The calibration item of disintegration time limited tester is more, shares five：Distance is moved up and down including hanging basket
The limits of error, the hanging basket roundtrip frequency limits of error, the timing relative error of timer, maximum temperature allowable error,
The disintegration time error of indication.Therefore, the time measured used in an instrument is longer, about 3.5~4 hours.General pharmacy enterprise
The disintegration tester being equipped in industry laboratory is at 10~20 or so, and the long development examined and determine for factory under disintegration tester of prover time is very
It is unfavorable.In addition, currently, the calibration method of disintegration time limited tester, mainly utilizes three kinds of slide calliper rule, stopwatch, thermometer standards pair
The multi-parameter of disintegration time limited tester is calibrated.These standards will produce larger error in a calibration process, drop significantly
Low calibration accuracy, and need longer prover time.Disintegration time is measured using stopwatch, can not accurately judge to be disintegrated
Whether time limit standard substance is disintegrated the time point leached completely, and when the up-down vibration of disintegration tester hanging basket is disintegrated naked-eye observation
Between also result in prodigious influence, time precision can not ensure.With disintegration time limited tester answering extensively in industries such as medicine
With, disintegration time limited tester gage work cumulative year after year, original metering method cannot be satisfied more and more customer demands,
The urgently fast integration formula disintegration time limited tester calibration device of development of new.
It is traditional that by naked-eye observation clocking method, for the calibration of disintegration time this main project, there are large errors.
This is because the measurement that disintegration time limited standard substance is all disintegrated the time leached is only easy that there are larger meters with naked-eye observation
When error, and hanging basket is at work in up-down vibration, and leaching the time to observation disintegration impacts.Currently, domestic do not collapse still
Solve the calibrating installation of time limit tester.Therefore, grinding for the integrated form disintegration time limited tester calibration device that can quickly measure
Send out extremely urgent.
Utility model content
The purpose of this utility model aims to solve at least one of the technological deficiency.
To achieve the goals above, the embodiment of the utility model one side provides a kind of integrated form based on optical correction
Disintegration time limited tester calibration device, including optical-electric module, electronic counting module, temperature measurement module, range finder module and data processing
Module；The optical-electric module includes laser emitter, photoelectric detector and photoelectricity timing module, and the laser emitter setting exists
The side of constant temperature beaker, the photoelectric detector are arranged in the other side of constant temperature beaker, and the photoelectricity timing module connects photoelectricity
Detector counts the medicine disintegration time；The temperature measurement module is arranged in constant temperature beaker, the electronic counting module and ranging mould
Block is arranged on the hanging basket holder of disintegration tester；The optical-electric module, electronic counting module, temperature measurement module, range finder module connect respectively
Connect data processing module；The control system of the data processing module connection disintegration tester.
Preferably, power supply and laser beam expander are additionally provided in the optical-electric module；The laser emitter, laser expand
Beam device, photoelectric detector and photoelectricity timing module are separately connected power supply；The input terminal of the laser beam expander connects laser
The output end of transmitter.
Preferably, the temperature measurement module includes multiple temperature sensors, and each temperature sensor setting is burnt in constant temperature
In cup, the temperature of liquid in constant temperature beaker is detected.
Preferably, the electronic counting module includes frequency counter；The frequency counter is arranged on hanging basket holder,
The frequency round-trip for counting hanging basket.
Preferably, the range finder module is arranged at the hanging basket of disintegration tester, the round-trip distance of the hanging basket for detecting disintegration tester.
Preferably, the disintegration tester includes constant temperature beaker, disintegration tester control system, timekeeping system, the hanging basket branch that can be lifted
Frame and hanging basket, hanging basket lower end stud with sieve, and hanging basket is hung on by the stainless steel shaft of epimere on hanging basket holder, and immerses constant temperature
In beaker.
Further, when the hanging basket declines, sieve is away from constant temperature beaker bottom 25mm, when adjusting height of water level makes hanging basket rise
Sieve is in underwater 15mm.
A kind of integrated form disintegration time limited tester calibration based on optical correction provided according to the utility model embodiment
Device has at least the following advantages：Using optical-electric module, electronic counting module, temperature measurement module, range finder module and data processing mould
Block is combined the parameter correction realized to disintegration tester；It installs laser light source additional laser beam expander, expands the area of detection of light source,
So that light source detection area Landfill covering is entirely disintegrated region, avoid causing the feelings judged by accident because light beam is not by disintegration region
Condition obtains science, accurate calibration result；When the disintegration time obtained using optical correction's method is than the disintegration that naked-eye observation is arrived
Between more accurate, science, avoid the influence of human factor and other disturbing factors to testing result, substantially increase disintegration tester
The accuracy of metering and confidence level.
The additional aspect of the utility model and advantage will be set forth in part in the description, partly will be from following description
In become apparent, or recognized by the practice of the utility model.
Description of the drawings
The above-mentioned and/or additional aspect and advantage of the utility model will in the description from combination following accompanying drawings to embodiment
Become apparent and is readily appreciated that, wherein：
Fig. 1 is a kind of integrated form disintegration time limited tester calibration based on optical correction that the utility model embodiment provides
The schematic diagram of device；
Fig. 2 is a kind of integrated form disintegration time limited tester calibration device based on optical correction provided with new embodiment
Structural schematic diagram；
In figure：1, optical-electric module；2, electronic counting module；3, temperature measurement module；4, range finder module；5, data processing module；
6, constant temperature beaker；7, hanging basket holder；8, hanging basket；9, disintegration tester control system；101, laser emitter；102, photoelectric detector；
103, photoelectricity timing module；104, power supply；105, laser beam expander；
Specific implementation mode
The embodiments of the present invention are described below in detail, examples of the embodiments are shown in the accompanying drawings, wherein from beginning
Same or similar element or element with the same or similar functions are indicated to same or similar label eventually.Below by ginseng
The embodiment for examining attached drawing description is exemplary, it is intended to for explaining the utility model, and should not be understood as to the utility model
Limitation.
The operation principle of the utility model is that standard substance, can moment disintegration, formation particle or floccule in disintegration.
In disintegration moment prodigious change occurs for this spatial distribution for allowing for medium in hanging basket solution.Using this disintegration phenomenon, lead to
It crosses laser to detect solution in hanging basket, finally obtains the calibration result of disintegration time.
As shown in Figure 1, light is propagated in the medium, it may occur that the reflection of light, refraction and scattering.In different medium, light
The decaying of propagation path and light in the medium can change, to make the light intensity of transmitted light change.
The optical signal of transmitted intensity passes through photoelectric detector, is converted into electric signal.When being disintegrated generation, photoelectric detector
The electric signal detected will also change due to the change of medium in propagation path of light.The electric signal is transmitted to time timing
Device terminates the timing to disintegration time, obtains the calibration result of disintegration time.The disintegration that method obtains using this optical correction
Time is more more accurate than the disintegration time that naked-eye observation is arrived, science, substantially increases accuracy and the confidence level of disintegration tester metering.
On this basis, as shown in Fig. 2, the utility model embodiment proposes a kind of integrated form disintegration based on optical correction
Time limit tester calibration device, including optical-electric module 1, electronic counting module 2, temperature measurement module 3, range finder module 4 and data processing
Module 5；Optical-electric module includes laser emitter 101, photoelectric detector 102 and photoelectricity timing module 103, laser emitter 101
It is arranged in the side of constant temperature beaker, photoelectric detector 102 is arranged in the other side of constant temperature beaker, and temperature measurement module 3 is arranged in constant temperature
In beaker, photoelectricity timing module 103 connects photoelectric detector 102, counts the medicine disintegration time；Electronic counting module 2 and ranging
Module 4 is arranged on the hanging basket holder of disintegration tester；Optical-electric module, electronic counting module 2, temperature measurement module 3, range finder module 4 are distinguished
Connect data processing module 5；Data processing module 5 connects disintegration tester control system 9, and data processing module can also pass through USB
PC is connected, data analysis is carried out using PC.
In one embodiment of the utility model, wait for that disintegrating medicinal is placed in the hanging basket of disintegration tester, hanging basket passes through branch
Frame control drops in constant temperature beaker, and laser emitter 101 emits laser direct projection constant temperature beaker, at this point, due to medicine disintegration, it is permanent
It changes before and after medium in warm beaker, when laser irradiation is in constant temperature beaker, is disintegrated front and back light intensity difference, at this time position
Photoelectric detector 102 in the constant temperature beaker other side, due to light intensity difference, the monitoring signals sent out are also different.Utilize the present apparatus
Accuracy of timekeeping：Reach 0.1s；Temperature accuracy：Reach 0.1 DEG C；Range accuracy：Reach 0.5mm.
Power supply 104 and laser beam expander 105 are additionally provided in optical-electric module；Laser emitter 101, laser beam expander
105, photoelectric detector 102 and photoelectricity timing module 103 are separately connected power supply 104；The input terminal of laser beam expander 105 connects
Connect the output end of laser emitter 101.The light beam that laser light source generates is very thin, and the measurement of disintegration time is easy tod produce partially
From therefore, installing laser light source additional laser beam expander, expand the area of detection of light source so that light source detection area finally covers
Entire disintegration region is covered, the case where avoiding causing to judge by accident due to light beam is by being disintegrated region, obtains science, accurately calibration
As a result.
Temperature measurement module 3 includes multiple temperature sensors, and the constant temperature beaker in disintegration tester is arranged in each temperature sensor
In, test the temperature of liquid in constant temperature beaker.Multiple temperature sensors detect simultaneously, are burnt the mean value of detection as constant temperature at this time
Temperature in cup.Electronic counting module 2 is frequency counter；Frequency counter is arranged on hanging basket holder, for counting hanging basket
Round-trip frequency.
Range finder module 4 is arranged at the hanging basket of disintegration tester, the round-trip distance of the hanging basket for detecting disintegration tester, so that it is determined that hanging
The limits of error of basket holder raising and lowering adjustment, are corrected hanging basket holder raising and lowering distance.Range finder module 4
Including range laser transmitter, photoelectric cell and timer；Range laser transmitter projects a branch of very thin to target at work
Laser, the laser beam of target reflection is received by photoelectric cell, timer measures laser beam from the time for being emitted to reception, adjusts
Hanging basket is from peak to minimum point, by timer from the time difference for being emitted to receiving, you can measure what hanging basket moved up and down
Distance.By the distance of the hanging basket movement of measurement, the displacement distance of hanging basket holder is controlled in disintegration tester control system, is repaiied
Just.
In one embodiment of the utility model, disintegration tester includes constant temperature beaker 6, disintegration tester control system 9, timing system
System, the hanging basket holder 7 that can be lifted and hanging basket 8, hanging basket lower end stud with sieve, and hanging basket is hung on by the stainless steel shaft of epimere and hung
On basket holder, and immerse in constant temperature beaker.
When hanging basket declines, sieve fills the water of 37 ± 1 DEG C of temperature away from constant temperature beaker bottom 25mm in beaker, adjust water level
Sieve is in underwater 15mm when height makes hanging basket rise.
When the utility model is used, will wait for that disintegrating medicinal is arranged in hanging basket, hanging basket holder is controlled by control system,
Disintegration terminates.Set disintegration time, the distance of hanging basket movement.The timekeeping system of disintegration tester starts timing, and hanging basket holder drives
Hanging basket, which declines, to be immersed in constant temperature beaker, opening optical-electric module, laser transmitter projects laser, and photoelectric detector receives at this time
Light intensity signal is most strong, will wait for that disintegrating medicinal is placed in hanging basket, and the control system control hanging basket holder of disintegration tester carries under hanging basket
Drop, when hanging basket, which declines, to be immersed in constant temperature beaker, electronic counting module starts counting up, and range finder module starts to measure the movement of hanging basket
Distance, optical-electric module start timing, and with the progress of disintegration, the medium of laser irradiation changes, at this point, light spot detector is received
The optical signal arrived weakens, and when being disintegrated completion, optical signal weakens to certain certain value, and remains unchanged, and optical-electric module timing terminates,
Optical-electric module sends the technical data to data processing module, when the control system control hanging basket holder of disintegration tester rises, electronics
Counting module terminates to count, and range finder module terminates ranging, and the chronometric data and ranging data are sent to data processing module,
The data of acquisition are sent to the control system of disintegration tester by data processing module, disintegration time, hanging basket to disintegration tester setting
Roundtrip frequency and round-trip distance are corrected.
As disintegration time limited tester is in the extensive use of the industries such as medicine, disintegration time limited tester gage work is passed year by year
Increase, original metering method cannot be satisfied more and more customer demands.Disintegration time limited tester calibration device is integrated with temperature
Degree, displacement distance, time multiple calibration modules not only substantially increase school using high-precision laser and photoelectric detector
Quasi- precision avoids influence of the human factor to testing result, and has filled up the market of disintegration time limited tester calibration device as possible
Blank, economic benefit foreground are huge.
Disintegration time limited tester calibration device can be used as the Main Regulator of calibration disintegration tester, can not only improve disintegration tester
Accuracy of detection reduces influence of the human factor to calibration result, and can greatly improve working efficiency, realizes quickly, accurately
Metering.Disintegration time limited tester calibration device has filled up China in the blank of the measuring and testing device in the field, is passed in magnitude
It passes more accurate, just, change social user can be marked by the doubt of this kind of instrument metering method plus corresponding metering significantly
Quasi- release can be such that a variety of different samplers obtain on the apparatus, and believable consistency is good as a result, social benefit is aobvious and easy
See.
In the description of this specification, reference term " one embodiment ", " some embodiments ", " example ", " specifically show
The description of example " or " some examples " etc. means specific features, structure, material or spy described in conjunction with this embodiment or example
Point is contained at least one embodiment or example of the utility model.In the present specification, to the schematic table of above-mentioned term
It states and may not refer to the same embodiment or example.Moreover, particular features, structures, materials, or characteristics described can be
It can be combined in any suitable manner in any one or more embodiments or example.
Although the embodiments of the present invention have been shown and described above, it is to be understood that above-described embodiment is
Illustratively, it should not be understood as limiting the present invention, those skilled in the art are not departing from the utility model
Principle and objective in the case of above-described embodiment can be changed in the scope of the utility model, change, replace and
Modification.The scope of the utility model is by appended claims and its equivalent limits.
Claims (7)
1. a kind of integrated form disintegration time limited tester calibration device based on optical correction, which is characterized in that including optical-electric module,
Electronic counting module, temperature measurement module, range finder module and data processing module；The optical-electric module includes laser emitter, photoelectricity
Detector and photoelectricity timing module, the laser emitter are arranged in the side of constant temperature beaker, and the photoelectric detector setting exists
The other side of constant temperature beaker, the photoelectricity timing module connect photoelectric detector, count the medicine disintegration time；The temperature measurement module
It is arranged in constant temperature beaker, the electronic counting module and range finder module are arranged on the hanging basket holder of disintegration tester；The photoelectricity
Module, electronic counting module, temperature measurement module, range finder module are separately connected data processing module；The data processing module connection
The control system of disintegration tester.
2. the integrated form disintegration time limited tester calibration device according to claim 1 based on optical correction, feature exist
In being additionally provided with power supply and laser beam expander in the optical-electric module；The laser emitter, laser beam expander, photoelectricity inspection
It surveys device and photoelectricity timing module is separately connected power supply；The output of the input terminal connection laser emitter of the laser beam expander
End.
3. the integrated form disintegration time limited tester calibration device according to claim 1 based on optical correction, feature exist
In the temperature measurement module includes multiple temperature sensors, and each temperature sensor is arranged in constant temperature beaker, detects beaker
The temperature of middle liquid.
4. the integrated form disintegration time limited tester calibration device according to claim 1 based on optical correction, feature exist
In the electronic counting module includes frequency counter；The frequency counter is arranged on hanging basket holder, for counting hanging basket
Round-trip frequency.
5. the integrated form disintegration time limited tester calibration device according to claim 1 based on optical correction, feature exist
In the range finder module is arranged at the hanging basket of disintegration tester, the round-trip distance of the hanging basket for detecting disintegration tester.
6. the integrated form disintegration time limited tester calibration device according to claim 1 based on optical correction, feature exist
In the disintegration tester includes constant temperature beaker, disintegration tester control system, timekeeping system, the hanging basket holder and hanging basket that can be lifted, hanging basket
Lower end studs with sieve, and hanging basket is hung on by the stainless steel shaft of epimere on hanging basket holder, and is immersed in constant temperature beaker.
7. the integrated form disintegration time limited tester calibration device according to claim 6 based on optical correction, feature exist
In when the hanging basket declines, sieve is away from constant temperature beaker bottom 25mm, and sieve is in underwater when adjusting height of water level makes hanging basket rise
15mm。
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115097089A (en) * | 2022-08-25 | 2022-09-23 | 江苏省计量科学研究院(江苏省能源计量数据中心) | Metering method and system of drug disintegration time limit tester |
-
2018
- 2018-01-19 CN CN201820093710.7U patent/CN207832780U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115097089A (en) * | 2022-08-25 | 2022-09-23 | 江苏省计量科学研究院(江苏省能源计量数据中心) | Metering method and system of drug disintegration time limit tester |
| CN115097089B (en) * | 2022-08-25 | 2023-08-18 | 江苏省计量科学研究院(江苏省能源计量数据中心) | Metering method and system of medicine disintegration time limit tester |
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