CN207738762U - A kind of device for making cell mechanical injury model - Google Patents

Abstract

The utility model discloses a kind of devices for making cell mechanical injury model, including tissue culture plate (1) He Bangai (2), it is provided with mating mould plate (3) between the tissue culture plate (1) and plate lid (2), mould plate (3) can be fastened on culture plate upper end, and mould plate (3) position of each culture hole on corresponding tissue culture plate (1) is equipped with " # " font groove (4).Apparatus structure provided by the utility model is simple, easy to use, can ensure that scribing line range, light and heavy degree are identical, and what is drawn is straight line, is suitable for the tissue culture plates such as 6 holes, 24 holes, 48 holes.

Description

A kind of device for making cell mechanical injury model

Technical field

The utility model is related to technical field of cell culture, more particularly to one kind is for making cell mechanical injury model Device.

Background technology

Cellular damage model establishes various cellular damage models according to clinical impairment factor, as cell factor damages mould Type, Hypoxia-reoxygenation damage model and mechanical injury model etc..

For the body injury caused by wound, need to establish cell mechanical injury model to simulate, in most of reality It tests in research, is nearly all that be drawn using 200ul pipette tips or sterile razor blade be in " # " font cut, realized with this damaging cells Mechanical injury model is established in the foundation of model, generally can all carry out evaluation or pharmaceutical intervention, if the standard of damage is not One, such as degree of damage weight in different culture dishes is different, and cut is uneven, and the range of damage is different, directly results in model The result of the disunity of foundation, evaluation is inaccurate, is in " # " font cut due to artificially only being drawn with pipette tips or sterile razor blade, must It so will appear the range of cut, the disunity standard of light and heavy degree directly affects foundation and the experimental result of damage model.Cause This, establishes a kind of device of the cell mechanical injury model of standard, can significantly reduce cut error, utmostly It is unified to reach injury criterion, with this be conducive to experiment be smoothed out and the accuracy of result evaluation.

Utility model content

In view of the deficiencies of the prior art, the utility model provides a kind of dress for making cell mechanical injury model It sets, can easily and fast, accurately draw unified " # " word, facilitate and establish cell mechanical injury model.

The technical solution of the utility model is as follows：A kind of device for making cell mechanical injury model, including it is thin Born of the same parents' culture plate and Ban Gai, are provided with mating mould plate between the tissue culture plate and plate lid, mould plate can be fastened on culture Plate upper end, mould plate position of each culture hole on corresponding tissue culture plate are equipped with " # " font groove.

Further, the mould plate is fastened on the upper end of tissue culture plate, and plate lid is fastened on the upper end of mould plate, model The side of plate is detachable connection with the bottom edge of plate lid.

Further, the lower end of the plate lid be equipped with arc elastic slot, mould plate side be equipped with tongue, tongue with insert Slot is mating, and tongue is inserted into slot and can rotate.

Further, the mould plate is spliced by the cell board equipped with " # " font groove.

Further, described device further includes that model draws nail or model draws knife, model draw nail or model draw knife can be along " # " font groove draws corresponding shape.

The operation principle of the utility model is as follows：The utility model increases model on the basis of existing tissue culture plate Plate, mould plate position of each culture hole on corresponding tissue culture plate are equipped with " # " font groove, and mould plate is fastened on cell training The upper end of plate is supported, plate lid is fastened on the upper end of mould plate, and the side of mould plate is detachable connection with the bottom edge of plate lid, when need When establishing mechanical damage model, after mould plate is fastened on the upper end of tissue culture plate, draws nail using model or model draws knife " # " word is drawn along " # " font groove.Under normal condition, what plate lid and mould plate were connected together, if early period is thin Born of the same parents' culture does not need mould plate, then can cover mould plate from plate and disassemble.In addition, when making cell machinery damage model, Several cell board assembly equipped with " # " font groove are formed mould plate, save material by the number that can make model as needed Material, flexibility are high.

Compared with prior art, the utility model has the advantages that：Apparatus structure letter provided by the utility model It is single, it is easy to use, it can ensure that scribing line range, light and heavy degree are identical, and what is drawn is straight line, is suitable for 6 holes, 24 holes, 48 The tissue culture plates such as hole.

Description of the drawings

Fig. 1 is the structural schematic diagram provided by the utility model for making the device of cell mechanical injury model；

Fig. 2 is the side view of described device；

Fig. 3 is the floor map of mould plate；

Fig. 4 is the sectional view of mould plate；

Fig. 5 is the structural schematic diagram that model draws knife；

It is marked in figure：1- tissue culture plates, 2- plate lids, 3- mould plates, 4- " # " font grooves, 5- cell boards, 6- models are drawn Knife, 7- slots, 8- tongues.

Specific implementation mode

Technical scheme of the present invention is described in further details with reference to specific embodiment, but the utility model is not It is confined to following technical scheme.

Embodiment 1

As shown in fig. 1~fig. 5, a kind of device for making cell mechanical injury model, including 1 He of tissue culture plate Plate lid 2, is provided with mating mould plate 3 between the tissue culture plate 1 and plate lid 2, mould plate 3 is fastened on tissue culture plate 1 Upper end, plate lid 2 is fastened on the upper end of mould plate 3, and the side of mould plate 3 is detachable connection with the bottom edge of plate lid 2, such as may be used It is equipped with arc elastic slot 7 in the lower end of plate lid 2,3 side of mould plate is equipped with tongue 8, and tongue 8, which is inserted into slot 7, to be revolved Turn.

The position of each culture hole on corresponding tissue culture plate 1 of mould plate 3 is equipped with " # " font groove 4.Described device is also Knife 6 is drawn including model, model draws knife 6 can draw corresponding shape along " # " font groove, see Fig. 5.

As an improvement, the mould plate 3 can be also spliced by the cell board 5 equipped with " # " font groove, Fig. 3 and figure are seen 4, cell board both sides are equipped with slot, and in addition both sides are equipped with tongue, pass through slot and the mating splicing of tongue.

Described device use process is as follows：After cell culture is good, mould plate 3 is fastened on to the upper end of tissue culture plate 1, Model, which draws knife, to draw " # " word model along the edge of " # " font groove.

The technical solution of the utility model is completed under the support of following fund project, project of national nature science fund project (No：31560295)；Yunnan Province's applied basic research (it is special that elder brother cures joint) (No:2015FB098)；Yunnan Province's health science and technology meter Draw project (No:2014NS202).

Claims (5)

1. a kind of device for making cell mechanical injury model, including tissue culture plate (1) He Bangai (2), feature It is, mating mould plate (3) is provided between the tissue culture plate (1) and plate lid (2), and mould plate (3) can be fastened on training Plate upper end is supported, mould plate (3) position of each culture hole on corresponding tissue culture plate (1) is equipped with " # " font groove (4).

2. a kind of device for making cell mechanical injury model as described in claim 1, which is characterized in that the mould Template (3) is fastened on the upper end of tissue culture plate (1), and plate lid (2) is fastened on the upper end of mould plate (3), the side of mould plate (3) Bottom edge with plate lid (2) is detachable connection.

3. a kind of device for making cell mechanical injury model as claimed in claim 2, which is characterized in that the plate The lower end for covering (2) is equipped with arc elastic slot (7), and mould plate (3) side is equipped with tongue (8), and tongue (8) and slot (7) are mating, And tongue (8) is inserted into slot (7) and can rotate.

4. a kind of device for making cell mechanical injury model as described in claim 1, which is characterized in that the mould Template (3) is spliced by the cell board (5) equipped with " # " font groove.

5. a kind of device for making cell mechanical injury model as described in Claims 1 to 4 is any, feature exist In described device further includes that model draws nail or model stroke knife (6), and model stroke nail or model draw knife (6) can be recessed along " # " font Slot draws corresponding shape.