CN207623356U - A kind of wash mill for chemiluminescence immunoassay detection - Google Patents
A kind of wash mill for chemiluminescence immunoassay detection Download PDFInfo
- Publication number
- CN207623356U CN207623356U CN201721856323.6U CN201721856323U CN207623356U CN 207623356 U CN207623356 U CN 207623356U CN 201721856323 U CN201721856323 U CN 201721856323U CN 207623356 U CN207623356 U CN 207623356U
- Authority
- CN
- China
- Prior art keywords
- permanent magnet
- plate
- magnet
- movement
- support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model is related to a kind of wash mills for chemiluminescence immunoassay detection, when working which solve existing wash module, magnetic bead cannot rapidly, the technical issues of being separated from reaction solution completely, it includes plate in supporting back board, support, center platen, movement upper plate, movement lower plate and sliding rail, sliding rail is connected in supporting back board, sliding block is connected on sliding rail, plate is fixed together in center platen and support, and sliding block is connect with the inside of plate in support；The reaction cup support portion for placing response cup is equipped in center platen and support between plate；Lower lead screw motor and upper screw rod motor are connected in supporting back board, movement upper plate is connect by top nut with the lead screw of upper screw rod motor；The inside of movement upper plate is connect with sliding block；Movement lower plate is connect by lower nut with the lead screw of lower lead screw motor, and the inside for moving lower plate is connect with sliding block；Movement lower plate is connected with magnet assemblies pedestal, and magnet assemblies pedestal is connected with magnet assemblies.The utility model is widely used in chemiluminescence immunoassay detection technique field.
Description
Technical field
The utility model is related to chemiluminescence immunoassay detection technique fields, and chemiluminescence is used in particular to one kind
The wash mill of immune detection.
Background technology
Chemical illumination immunity analysis instrument have accuracy height, high sensitivity, detection time is short, detection range is wide, pollution-free
The advantages that, it is used widely in fields such as hospital clinical diagnosis.
Chemiluminescence immune assay is will be with the immune anti-of highly sensitive chemical luminescent detecting method and high specific
Induction method is combined, so as to the various antigens of quantitative detection, haptens, antibody, hormone, enzyme, aliphatic acid, vitamin and drug etc.
Analytical technology.
Existing Full-automatic chemiluminescence immunoassay analysis meter generally includes following functions module：Sample storage module, reagent
Storage module, sample distribution module, reagent dispensing module, reaction cup storage module, raising module, wash module, measurement module.
Detection process generally comprises：Sample and reagent are respectively put into sample storage module and reagent storage module first, then by sample
This and reagent are added in reaction cup, and reaction cup is then made by incubation, wash module processing, finally reaction cup to be made to enter respectively
Measurement module carries out outcome measurement.
At work, the time that magnetic bead is isolated from reaction solution in reaction cup is long for existing wash module, and magnetic bead is easy
It omits, magnetic bead cannot be separated from reaction solution completely.
Invention content
When the utility model is exactly to solve the work of existing wash module, magnetic bead cannot rapidly, completely from reaction solution
In the technical issues of separating, providing one kind can rapidly, the use for thoroughly separating magnetic bead from reaction solution
In the wash mill of chemiluminescence immunoassay detection.
It is provided by the utility model for chemiluminescence immunoassay detection wash mill include plate in supporting back board, support,
Center platen, movement upper plate, movement lower plate, sliding rail, lower lead screw motor, upper screw rod motor, top nut, lower nut, aspirating needle, fluid injection
Needle, magnet assemblies and magnet assemblies pedestal, the sliding rail are connected in supporting back board, are connected with sliding block on sliding rail, center platen and
Plate is fixed together in support, and the inside connection of plate, supporting back board are disposed vertically in the sliding block and support on the sliding rail,
Plate is slidably connected with supporting back board in support；
The reaction cup support portion for placing response cup is equipped in center platen and support between plate；Injection needle connects with center platen
It connects；
Upper screw rod motor is connected in supporting back board, and top nut is connect with the lead screw of upper screw rod motor, movement upper plate with it is upper
Nut connects；The sliding block connection on the inside and sliding rail of upper plate is moved, the aspirating needle passes through movement upper plate；
Lower lead screw motor is connected in supporting back board, and lower nut is connect with the lead screw of lower lead screw motor, and movement lower plate is under
Nut connects, the sliding block connection on the inside and sliding rail of the movement lower plate；
Magnet assemblies pedestal with movement lower plate connect, magnet assemblies are connect with magnet assemblies pedestal, magnet assemblies include from
Top to bottm connected permanent magnet a, permanent magnet b and permanent magnet c；
The top that upper plate is located at plate in support is moved, movement lower plate is located at the lower section of plate in support.
Preferably, permanent magnet b is identical with the size of permanent magnet c, and the size of permanent magnet a is less than the size of permanent magnet b.
Preferably, the height of permanent magnet a is h, and the height of permanent magnet b is H, H/3≤h≤H/2.
Preferably, permanent magnet a, permanent magnet b and the magnetic pole of the same sides permanent magnet c are the poles N, the poles N and the poles S respectively.
Preferably, the wash mill for chemiluminescence immunoassay detection further includes resetting swing arm and shrapnel；Magnet assemblies bottom
Seat is L-type, is made of upper and lower part, and top is equipped with magnet assemblies interconnecting piece, the magnet of magnet assemblies and magnet assemblies pedestal
Component interconnecting piece connects, and the reset swing arm and the lower part left end of magnet assemblies pedestal are hinged, the lower end of shrapnel and magnet assemblies
The lower part left end connection of pedestal, upper end is pressed in the top for resetting swing arm.
Preferably, the reaction cup support portion between plate in center platen and support is stretched into the end of injection needle, under aspirating needle
Hold orientating reaction cup support portion.
The utility model also provides a kind of wash mill for chemiluminescence immunoassay detection, including magnet assemblies pedestal,
Magnet assemblies pedestal is connected with magnet assemblies, and magnet assemblies include connected from top to bottom permanent magnet a, permanent magnet b and permanent magnet
c。
Preferably, permanent magnet b is identical with the size of permanent magnet c, and the size of permanent magnet a is less than the size of permanent magnet b.
Preferably, the height of permanent magnet a is h, and the height of permanent magnet b is H, H/3≤h≤H/2.
Preferably, permanent magnet a, permanent magnet b and the magnetic pole of the same sides permanent magnet c are the poles N, the poles N and the poles S respectively.
The utility model has the beneficial effects that magnet assemblies are more thorough to the absorption of magnetic bead, effect is more preferable, can inhale completely
Attached magnetic bead will not be omitted.The time that magnetic bead is isolated from reaction solution is shorter.In addition, improving chemiluminescence immunoassay
The detection sensitivity of detection process.
The utility model further feature and aspect, by the description of the specific implementation mode below with reference to attached drawing,
It is clearly stated that.
Description of the drawings
Fig. 1 is the stereogram of wash mill；
Fig. 2 is the front view of wash mill；
Fig. 3 is the sectional view of wash mill；
Fig. 4 is the sectional view of wash mill；
Fig. 5 is the connection diagram for resetting swing arm and magnet assemblies pedestal；
Fig. 6 be aspirating needle be inserted into reaction cup and the bottom of reaction cup be clamped in reset swing arm and permanent magnet a it
Between schematic diagram；
Fig. 7 be reset in the middle part of reaction cup swing arm top and the schematic diagram that clamps of magnet assemblies；
Fig. 8 is that reaction cup is put into magnet assemblies and resets the schematic diagram being clamped between swing arm.
Symbol description in figure：
1. supporting back board, plate in 2. supports, 3. center platens, 4. movement upper plates, 5. movement lower plates, 6. first sliding rails, 7. the
Two sliding rails, 8. times lead screw motors, 9. upper screw rod motors, 10. top nuts, 11. aspirating needles, 12. injection needles, 13. reaction cups, 14.
Magnet assemblies, 14-1. permanent magnets a, 14-2. permanent magnet b, 14-3. permanent magnet c, 15. magnet assemblies pedestals, 15-1. magnet assemblies
Interconnecting piece, 16. reset swing arm, 17. shrapnels, 18. lower nuts, 19. magnetic beads.
Specific implementation mode
Referring to the drawings, the utility model is described in further detail with specific embodiment.
As shown in Figs. 1-5, for chemiluminescence immunoassay detection wash mill include supporting back board 1, support in plate 2, in
Pressing plate 3, movement upper plate 4, movement lower plate 5, the first sliding rail 6, the second sliding rail 7, lower lead screw motor 8, upper screw rod motor 9, top nut
10, lower nut 18, aspirating needle 11, injection needle 12, magnet assemblies 14, magnet assemblies pedestal 15, reset swing arm 16, shrapnel 17, fortune
Dynamic upper plate 4 is located at the top of plate 2 in support, and movement lower plate 5 is located at the lower section of plate 2 in support.
First sliding rail 6 and the second sliding rail 7 are mounted in supporting back board 1, and sliding block, the second sliding rail 7 are connected on the first sliding rail 6
On be connected with sliding block.Plate 2 is fixed together in center platen 3 and support, the first sliding rail 6, the sliding block on the second sliding rail 7 and branch
The inside connection of plate 2 in support.Supporting back board 1 is disposed vertically, and plate 2 is connect with motor-driven lead screw pair in support, plate 2 in support
It can move up and down.
Plate 2 is stacked together in center platen 3 and support, several reaction cup branch are equipped between plate 2 in center platen 3 and support
The reaction cup 13 of support part, respective numbers is placed in reaction cup support portion.
The inclination of several injection needles 12 is inserted into center platen 3, and plate in center platen 3 and support is stretched into the end of injection needle 12
The end of reaction cup support portion between 2, injection needle 12 is located at 13 open-topped top of reaction cup.Each reaction cup 13 corresponds to
One injection needle 12.
Upper screw rod motor 9 is mounted in supporting back board 1, and top nut 10 is connect with the lead screw of upper screw rod motor 9, moves upper plate
4 connect with top nut 10.The inside of movement upper plate 4 is connect with the sliding block on the first sliding rail 6, the second sliding rail 7.Several aspirating needles
11 pass through movement upper plate 4 to realize vertical connection, the lower end orientating reaction cup 13 of aspirating needle 11.The quantity and reaction cup of aspirating needle 11
13 quantity is identical.The action of upper screw rod motor 9 drives movement upper plate 4 to move up and down.
Lower lead screw motor 8 is mounted in supporting back board 1, and lower nut 18 is connect with the lead screw of lower lead screw motor 8, moves lower plate
5 connect with lower nut 18.The inside of movement lower plate 5 is connect with the sliding block on the first sliding rail 6, the second sliding rail 7.Lower lead screw motor 8
Action drives movement lower plate 5 to move up and down.
Magnet assemblies pedestal 15 is mounted in movement lower plate 5.Magnet assemblies pedestal 15 is L-type, is made of upper and lower part,
Top is equipped with magnet assemblies interconnecting piece 15-1.It resets swing arm 16 and the lower part left end of magnet assemblies pedestal 15 is hinged.Shrapnel 17
Lower end is connect with the lower part left end of magnet assemblies pedestal 15, and upper end is contacted with the extruding of swing arm 16 is resetted.Magnet assemblies 14 and magnet
The magnet assemblies interconnecting piece 15-1 connections of unitized substructure 15.Magnet assemblies 14 are disposed vertically.
Magnet assemblies 14 include stacking permanent magnet a14-1, the permanent magnet b14-2 to be connected together with gluing and forever from top to bottom
Magnet c14-3.Permanent magnet b14-2 is identical with the size of permanent magnet c14-3, and the size of permanent magnet a14-1 is less than permanent magnet b14-
2.Relationship between size for permanent magnet a14-1 and the size of permanent magnet b14-2, preferably scheme are：Permanent magnet a14-1
Height be h, the height of permanent magnet b14-2 is H, H/3≤h≤H/2.
The magnetic pole for the side that permanent magnet a14-1, permanent magnet b14-2 and permanent magnet c14-3 are contacted with reaction cup 13 is N respectively
Pole, the poles N and the poles S.
The design of permanent magnet a14-1, the dimension scale of permanent magnet b14-2 and permanent magnet c14-3 and magnetic pole can increase forever
The magnetic induction intensity of magnet a14-1 increases permanent magnet a14-1 to the adsorption capacity of remote magnetic bead, at the same can also allow magnetic bead according to
The magnetic force line tracking of permanent magnet b14-2 to c14-3 is run, and improves magnetic bead washing effect, when reducing absorption of the permanent magnet to magnetic bead
Between, the magnetic bead loss after magnetic bead washing is improved, chemiluminescence immunoassay detection sensitivity is improved.
It should be noted that making one that permanent magnet a14-1, permanent magnet b14-2 and permanent magnet c14-3 contact with reaction cup 13
The magnetic pole of side is the poles S, the poles S and the poles N respectively and feasible.
As shown in fig. 6, injection needle 12 is inserted into reaction cup 13, aspirating needle 11 is under the drive of movement upper plate 4 to underthrust
Enter into reaction cup 13.Injection needle 12 injects reaction solution into reaction cup 13.
As shown in Fig. 6,7 and 8, reaction cup 13 is stationary, and magnet assemblies pedestal 15 and reset swing arm 16 are in movement lower plate 5
Drive under move up, be gradually clamped in reaction cup 13 and reset between swing arm 16 and magnet assemblies 14.Shrapnel 17 it is upper
It holds to reset swing arm 16 and pressure is provided.Permanent magnet a14-1, permanent magnet b14-2 and permanent magnet c14-3 are close to the outer of reaction cup 13
Side.
Before the also not close permanent magnet a14-1 of reaction cup 13, magnetic bead 19 is located at reaction solution bottom in reaction cup 13, works as magnetic
When iron component 14 is moved along 13 side wall of reaction cup from bottom to top, permanent magnet c14-3, permanent magnet b14-2 and permanent magnet a14-1 meetings
Magnetic bead 19 in reaction solution is adsorbed onto liquid level or more (permanent magnet a14- from bottom to top from reaction solution along reaction cup madial wall
1 first adsorbs a part of magnetic bead, and then permanent magnet b14-2 adsorbs a part of magnetic bead again, and last permanent magnet c14-3 adsorbs remaining magnetic
Pearl), so that magnetic bead 19 is detached from reaction solution upper surface.
After magnetic bead 19 is detached from reaction solution upper surface, the work of aspirating needle 11 siphons away the reaction solution in reaction cup 13.Thus
Avoid the loss of magnetic bead.
The above is not intended to limit the utility model only to the preferred embodiment of the utility model, for this
For the technical staff in field, various modifications and changes may be made to the present invention.
Claims (10)
1. a kind of wash mill for chemiluminescence immunoassay detection, which is characterized in that including plate in supporting back board, support, in
Pressing plate, movement upper plate, movement lower plate, sliding rail, lower lead screw motor, upper screw rod motor, top nut, lower nut, aspirating needle, fluid injection
Needle, magnet assemblies and magnet assemblies pedestal, the sliding rail are connected in supporting back board, and sliding block, medium pressure are connected on sliding rail
Plate is fixed together in plate and support, and the inside connection of plate, supporting back board are vertical in the sliding block and support on the sliding rail
It places, plate is slidably connected with supporting back board in support；
The reaction cup support portion for placing response cup is equipped in medium pressure plate and support between plate；The injection needle and middle pressure
Plate connects；
The upper screw rod motor is connected in supporting back board, and top nut is connect with the lead screw of upper screw rod motor, movement upper plate with it is upper
Nut connects；Sliding block connection on the inside and sliding rail of the movement upper plate, the aspirating needle pass through movement upper plate；
The lower lead screw motor is connected in supporting back board, and lower nut is connect with the lead screw of lower lead screw motor, and movement lower plate is under
Nut connects, the sliding block connection on the inside and sliding rail of the movement lower plate；
The magnet assemblies pedestal is connect with movement lower plate, and magnet assemblies are connect with magnet assemblies pedestal, the magnet assemblies packet
Include connected from top to bottom permanent magnet a, permanent magnet b and permanent magnet c；
The top that upper plate is located at plate in support is moved, movement lower plate is located at the lower section of plate in support.
2. the wash mill according to claim 1 for chemiluminescence immunoassay detection, which is characterized in that the permanent magnet
B is identical with the size of permanent magnet c, and the size of permanent magnet a is less than the size of permanent magnet b.
3. the wash mill according to claim 2 for chemiluminescence immunoassay detection, which is characterized in that the permanent magnet
The height of a is h, and the height of permanent magnet b is H, H/3≤h≤H/2.
4. the wash mill according to claim 1,2 or 3 for chemiluminescence immunoassay detection, which is characterized in that described
Permanent magnet a, permanent magnet b and the magnetic pole of the same sides permanent magnet c are the poles N, the poles N and the poles S respectively.
5. the wash mill according to claim 1,2 or 3 for chemiluminescence immunoassay detection, which is characterized in that described
Wash mill for chemiluminescence immunoassay detection further includes resetting swing arm and shrapnel；The magnet assemblies pedestal is L-type, by upper
Portion and lower part composition, top are equipped with magnet assemblies interconnecting piece, and magnet assemblies and the magnet assemblies interconnecting piece of magnet assemblies pedestal connect
It connects, the reset swing arm and the lower part left end of magnet assemblies pedestal are hinged, and the lower end of shrapnel is left with the lower part of magnet assemblies pedestal
End connection, upper end are pressed in the top for resetting swing arm.
6. the wash mill according to claim 5 for chemiluminescence immunoassay detection, which is characterized in that the injection needle
End stretch into the reaction cup support portion in center platen and support between plate, the lower end orientating reaction cup support portion of aspirating needle.
7. a kind of wash mill for chemiluminescence immunoassay detection, which is characterized in that including magnet assemblies pedestal, the magnet
Unitized substructure is connected with magnet assemblies, and the magnet assemblies include connected from top to bottom permanent magnet a, permanent magnet b and permanent magnet
c。
8. the wash mill according to claim 7 for chemiluminescence immunoassay detection, which is characterized in that the permanent magnet
B is identical with the size of permanent magnet c, and the size of permanent magnet a is less than the size of permanent magnet b.
9. the wash mill according to claim 8 for chemiluminescence immunoassay detection, which is characterized in that the permanent magnet
The height of a is h, and the height of permanent magnet b is H, H/3≤h≤H/2.
10. the wash mill for chemiluminescence immunoassay detection according to claim 7,8 or 9, which is characterized in that described
Permanent magnet a, permanent magnet b and the magnetic pole of the same sides permanent magnet c are the poles N, the poles N and the poles S respectively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721856323.6U CN207623356U (en) | 2017-12-27 | 2017-12-27 | A kind of wash mill for chemiluminescence immunoassay detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721856323.6U CN207623356U (en) | 2017-12-27 | 2017-12-27 | A kind of wash mill for chemiluminescence immunoassay detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207623356U true CN207623356U (en) | 2018-07-17 |
Family
ID=62830333
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721856323.6U Active CN207623356U (en) | 2017-12-27 | 2017-12-27 | A kind of wash mill for chemiluminescence immunoassay detection |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207623356U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110127133A (en) * | 2019-04-29 | 2019-08-16 | 河南中烟工业有限责任公司 | A kind of spring-piece type cigarette packing machine forming container |
| CN111516957A (en) * | 2020-03-23 | 2020-08-11 | 浙江合众新能源汽车有限公司 | Fender department pastes word mark location and assists utensil |
-
2017
- 2017-12-27 CN CN201721856323.6U patent/CN207623356U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110127133A (en) * | 2019-04-29 | 2019-08-16 | 河南中烟工业有限责任公司 | A kind of spring-piece type cigarette packing machine forming container |
| CN111516957A (en) * | 2020-03-23 | 2020-08-11 | 浙江合众新能源汽车有限公司 | Fender department pastes word mark location and assists utensil |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103604939B (en) | A kind of Full-automatic luminescent immunoassay system based on micronano-magnetic bead electromagnetic transfer technique | |
| CN206339561U (en) | Small electrical chemical illumination immunity analysis instrument | |
| CN207623356U (en) | A kind of wash mill for chemiluminescence immunoassay detection | |
| CN110883001A (en) | Magnetic bead cleaning device for analyzer | |
| CN202083704U (en) | Full-automatic loading device | |
| CN104722526A (en) | Magnetism separating device | |
| CN108663502A (en) | Full-automatic thrombelastogram instrument | |
| CN104655831A (en) | Magnetic bead cleaning and separating device for full-automatic chemical luminescence immunity analyzer | |
| CN109239018B (en) | Full-automatic coagulation analysis system | |
| CN207380068U (en) | A kind of micro-fluidic chemiluminescent analyzer | |
| CN206146952U (en) | Sample system of magnetic particle chemiluminescence immunoassay analyzer | |
| CN206557223U (en) | Full-automatic thrombelastogram instrument | |
| WO2019127016A1 (en) | Automatic cleaning and separating device | |
| CN209690307U (en) | A kind of chemical composition of soil detection device based on chrysanthemum cultivation | |
| CN205463469U (en) | External immunological reagents's automatic cup wiper mechanism of sample | |
| CN211757232U (en) | Magnetic bead cleaning device for analyzer | |
| CN204544866U (en) | A kind of magnetic separating device | |
| CN109959782A (en) | A kind of pretreating device and method for chicken extracting solution | |
| CN201876373U (en) | Liquid stratified sampling device, analysis testing device and blood type analysis meter | |
| CN203705459U (en) | Full-automatic luminescence immunoassay system based on micro-nano magnetic bead electromagnetic transfer technology | |
| CN219574120U (en) | Enzyme-linked plate for pepsin detection kit production | |
| CN206258461U (en) | A kind of reaction cup automatic flushing device on time resolution detector | |
| CN217425525U (en) | Resistance measuring device | |
| CN107192841B (en) | One kind can drawing liquid manipulator | |
| CN204422539U (en) | The magnetic bead cleaning tripping device of Full-automatic chemiluminescence immunoassay analysis meter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |