CN207613764U - Device for detecting human body microvascular ultrastructure by circular polarization spectrum imaging - Google Patents
Device for detecting human body microvascular ultrastructure by circular polarization spectrum imaging Download PDFInfo
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Abstract
the utility model relates to an utilize circular polarization spectral imaging to survey device of human blood capillary ultrastructure, include light source module, beam split unit, camera lens module, polarizing plate and be the module of appearing at least, light source module includes the light source and is located the light source direction of illumination and is used for becoming the collimation unit that the column rectilinear propagation is changeed into to light, the camera lens module includes the imaging unit, is used for the camera lens unit of the enlarged formation of image of the observed object and is used for becoming the light modulation unit of circular polarization light with being used for, it is digital camera to appear the module.
Description
Technical field
The utility model is related to it is a kind of using optical image technology carry out medical diagnosis medical instrument, specifically one
Kind utilizes the device of circular polarization spectrum imaging detection human microvascular ultra microstructure.
Background technology
Microcirculation refers to the place of the blood and histocyte progress mass exchange between arteriole and venule.Microcirculation
Function, form and metabolism are completely to maintain human organ normal function institute conditio sune qua non.Pass through grinding for microcirculation
Study carefully, convenient for further appreciating that the specific function of each internal organs of human body, the pathogenesis of cognitive illnesses are conducive to disease prevention, diagnosis
And treatment.A variety of different morbid states include diabetes, and hypertension and coronary heart disease etc. can all cause the morbid state of microcirculation, packet
Include microvascular diameter, the variation of the parameters such as Ultrastructure speed in microvessel density and capilary, additionally it is possible to right
The haemocyte flowed in microvascular endothelial cells and capilary is observed.Therefore by understanding Ultrastructure situation
Microcirculation quality is held, for the diagnosing and treating of various diseases has extremely important effect.Ultrastructure feelings
Condition is so important to health and disease treatment, carries out high-precision digitlization quantification to Ultrastructure situation, realizes
Accurate diagnosis and treatment just have great necessity.In order to realize the accurate diagnosis and treatment for utilizing Ultrastructure, essential needs
Real-time high-definition imaging and digitized " noninvasive dynamic capilary can be carried out to Ultrastructure in the case that noninvasive
Ultra microstructure observation system ".
In medical domain, have much through the mode that skin is non-invasively imaged body interior, for example, computer is disconnected
Layer imaging (CT) technology and Magnetic resonance imaging (MRI) technology etc..Although the morning that these technologies generate, mature,
It is that the shortcomings of resolution ratio is low, and real-time is poor is not appropriate for surpassing Ultrastructure and capilary since equipment volume is big
Image microstructures are used.Wherein, cross-polarization spectrum (OPS) imaging technique is that Ultrastructure is imaged
A kind of new technology.
It can be in the noninvasive imaging system observed in real time to live body Ultrastructure in 1999
It is suggested [1]：Cross-polarization spectrum (OPS) imaging technique.The schematic diagram of the technology is as shown in Figure 1.Specifically：It is orthogonal inclined
In vibrational spectrum imaging technique, first with the light of special wavelength as imaging source, such light source can either be to a certain degree
On be scattered through skin and inside it and can be absorbed by the red blood cell in capilary.The trimmed book body that light source is sent out is
Non-polarized light needs to become linearly polarized photon through polarization plates (A).Then, linear polarization light source passes through positioned at system centre
Spectroscope is reflected into skin surface.Linearly polarized photon will produce two kinds of light when being irradiated to skin surface：With irradiation light polarization direction
Identical polarized reflection light and it is irradiated to the internal unpolarized scattering light that scattering occurs and loses unified polarizability.It is unpolarized to dissipate
It penetrates light and forms radiation source inside skin, and penetrate skin and be irradiated to together positioned at number by spectroscope with polarized reflection light
In polarization plates (B) in front of camera sensor CCD.At this moment, unpolarized scattering light is because reflect internal Ultrastructure
Situation and need to be imaged, but polarized reflection light then needs to be fallen as noise filtering.Because polarization plates B is inclined with polarization plates A's
The direction that shakes is orthogonal, that is, is orthogonal with the polarization direction of polarized reflection light.According to the characteristic of polarization plates, polarized reflection light meeting
It is reflected back by polarization plates B rather than polarization scattering light can be imaged by the polarization plates B by the surfaces CCD.In this way, passing through cross-polarization
Principle can in the noninvasive image for observing Ultrastructure in real time, here because red blood cell to light
Source has certain absorption, so it is able to observe that capilary is dark, the brighter image of hetero-organization.
1897870 A of Chinese patent CN《Device and method for carrying out orthogonal polarization spectral imaging (OPSI)》And
104783767 A of Chinese patent CN《A kind of device and method detecting microcirculation in human body using orthogonal polarization spectral imaging》
The cross-polarization spectrum that two pieces of mutually orthogonal polarizers of rotation angle and one piece of unpolarized optical splitter are constituted is disclosed to be imaged,
Linearly polarized light is substantially used as light source.Such imaging definition is not high, and two above patent can not be right
The ultra microstructure of human microvascular is observed.
Utility model content
To overcome above-mentioned shortcoming, the purpose of this utility model is to provide a kind of high utilization circle of imaging definition is inclined
The device of vibrational spectrum imaging detection human microvascular ultra microstructure.
To achieve the above object, the technical solution of the utility model is：It is a kind of to utilize circular polarization spectrum imaging detection people
The device of body Ultrastructure, it is characterised in that：Including at least light source module, spectrophotometric unit, camera lens module, polarization plates and
Imaging module；
Light source module includes light source and is used to changing into light into the standard for column straightline propagation on light source direction of illumination
Straight unit；
Camera lens module includes imaging unit, the lens unit for object being observed amplification to be imaged and is used for linear polarization
Light modulation at circularly polarized light dimming unit；
Imaging module is digital camera.
Preferably：The dimming unit is between spectrophotometric unit and imaging unit or positioned at imaging unit and mirror
Front end between head unit or positioned at lens unit.
Preferably：The dimming unit is 1/4 wavelength plate or 1/4 phase difference film.
Preferably：The collimation unit is non-spherical lens or planoconvex spotlight.
Preferably：The spectrophotometric unit is pellicle mirror or unpolarized optical splitter.
Preferably：The side of the spectrophotometric unit is provided with the barn door (7) for blocking the light through spectrophotometric unit.
Preferably：The lens unit is micro objective or Varifocal zoom lens.
Preferably：The light source is the LED or semiconductor laser for the plating polarizing coating that can send out linearly polarized light.
Preferably：Right angle plane of reflection mirror is equipped between the collimation unit and spectrophotometric unit.
Preferably：The light source module, spectrophotometric unit, camera lens module, polarization plates and imaging module outside be equipped with it is solid
Determine frame.
The beneficial effects of the utility model are：
(1) perpendicular linear polarization light is changed by circularly polarized light by 1/4 wavelength plate or 1/4 phase difference film, and be irradiated to
On human skin so that incident light has better transmission capacity and imaging definition, and therefore, the present apparatus has to be imaged than tradition
The better imaging performance of device；
(2) line light propagated with radiant type sent out from light source is changed by column line light by collimation unit,
The light efficiency for improving incident light, to improve the clarity of imaging；
(3) by external fixed frame, the present apparatus is contained in single unit system, and be arranged to handheld device, is used
It is convenient；
(4) by right angle plane of reflection mirror that the direction of light source module is consistent with the direction of imaging module so that entirely to set
It is standby compacter.
(5) ultra microstructures such as microvascular endothelial cells and haemocyte can be observed, is passed through by lens unit
Varifocal zoom lens in lens unit can either carry out macroscopic view observation in big field range to capilary also can be in low coverage model
It encloses and microcosmic observation is carried out to the ultra microstructure of capilary.
Description of the drawings
Fig. 1 is the principle schematic of the prior art；
Fig. 2 a are the light schematic diagrams one of the first embodiment of the utility model；
Fig. 2 b are the light schematic diagrams two of the first embodiment of the utility model；
Fig. 2 c are the light schematic diagrams three of the first embodiment of the utility model；
Fig. 2 d are the light schematic diagrams four of the first embodiment of the utility model；
Fig. 3 a are the structural schematic diagrams one of the first embodiment of the utility model；
Fig. 3 b are the structural schematic diagrams two of the first embodiment of the utility model；
Fig. 3 c are the structural schematic diagrams three of the first embodiment of the utility model；
Fig. 3 d are the structural schematic diagrams four of the first embodiment of the utility model；
Fig. 4 a are the light schematic diagrams one of the second embodiment of the utility model；
Fig. 4 b are the light schematic diagrams two of the second embodiment of the utility model；
Fig. 4 c are the light schematic diagrams three of the second embodiment of the utility model；
Fig. 4 d are the light schematic diagrams four of the second embodiment of the utility model；
Fig. 5 a are the structural schematic diagrams one of the second embodiment of the utility model；
Fig. 5 b are the structural schematic diagrams two of the second embodiment of the utility model；
Fig. 5 c are the structural schematic diagrams three of the second embodiment of the utility model；
Fig. 5 d are the structural schematic diagrams four of the second embodiment of the utility model；
Fig. 6 a are the light schematic diagrams one of the 3rd embodiment of the utility model；
Fig. 6 b are the light schematic diagrams two of the 3rd embodiment of the utility model；
Fig. 6 c are the light schematic diagrams three of the 3rd embodiment of the utility model；
Fig. 6 d are the light schematic diagrams four of the 3rd embodiment of the utility model；
Fig. 7 a are the structural schematic diagrams one of the 3rd embodiment of the utility model；
Fig. 7 b are the structural schematic diagrams two of the 3rd embodiment of the utility model；
Fig. 7 c are the structural schematic diagrams three of the 3rd embodiment of the utility model；
Fig. 7 d are the structural schematic diagrams four of the 3rd embodiment of the utility model；
Fig. 8 a are the light schematic diagrams one of the fourth embodiment of the utility model；
Fig. 8 b are the light schematic diagrams two of the fourth embodiment of the utility model；
Fig. 8 c are the light schematic diagrams three of the fourth embodiment of the utility model；
Fig. 8 d are the light schematic diagrams four of the fourth embodiment of the utility model；
Fig. 9 a are the structural schematic diagrams one of the fourth embodiment of the utility model；
Fig. 9 b are the structural schematic diagrams two of the fourth embodiment of the utility model；
Fig. 9 c are the structural schematic diagrams three of the fourth embodiment of the utility model；
Fig. 9 d are the structural schematic diagrams four of the fourth embodiment of the utility model；
Figure 10 a are the light schematic diagrams one of the 5th embodiment of the utility model；
Figure 10 b are the light schematic diagrams two of the 5th embodiment of the utility model；
Figure 10 c are the light schematic diagrams three of the 5th embodiment of the utility model；
Figure 10 d are the light schematic diagrams four of the 5th embodiment of the utility model；
Figure 11 a are the structural schematic diagrams one of the 5th embodiment of the utility model；
Figure 11 b are the structural schematic diagrams two of the 5th embodiment of the utility model；
Figure 11 c are the structural schematic diagrams three of the 5th embodiment of the utility model；
Figure 11 d are the structural schematic diagrams four of the 5th embodiment of the utility model；
Figure 12 a are the light schematic diagrams one of the sixth embodiment of the utility model；
Figure 12 b are the light schematic diagrams two of the sixth embodiment of the utility model；
Figure 12 c are the light schematic diagrams three of the sixth embodiment of the utility model；
Figure 12 d are the light schematic diagrams four of the sixth embodiment of the utility model；
Figure 13 a are the structural schematic diagrams one of the sixth embodiment of the utility model；
Figure 13 b are the structural schematic diagrams two of the sixth embodiment of the utility model；
Figure 13 c are the structural schematic diagrams three of the sixth embodiment of the utility model；
Figure 13 d are the structural schematic diagrams four of the sixth embodiment of the utility model；
Figure 14 is the structural schematic diagram of the double glued achromatic lens of the utility model.
In figure, 1- light sources；2- collimation units；3- spectrophotometric units；4- imaging units；5- lens units；6- dimming units；7-
Barn door；8- polarization plates；9- imaging modules；10- fixed frames；The right angles 11- plane of reflection mirror；12- lenticular lens；13- is recessed
Convex lens.
Specific implementation mode
The utility model is described further with reference to specific embodiment.
The utility model is related to a kind of devices using circular polarization spectrum imaging detection human microvascular ultra microstructure, at least
Including light source module, spectrophotometric unit 3, camera lens module, polarization plates 8 and imaging module 9；Wherein, light source module includes light source 1 and position
In on 1 direction of illumination of light source for light to be changed into the collimation unit 2 for column straightline propagation；Camera lens module includes imaging unit
4, the lens unit 5 for object being observed amplification to be imaged and the dimming unit for linearly polarized light to be modulated into circularly polarized light
6；Imaging module 9 is digital camera.
The utility model is divided into 3 kinds of situations according to the position of dimming unit, below according to dimming unit position difference into
Row detailed description.
Embodiment 1
Device using circular polarization spectrum imaging detection human microvascular ultra microstructure as Figure 2-3, includes at least
Light source module, spectrophotometric unit 3, camera lens module, polarization plates 8 and imaging module 9；Wherein, light source module include light source 1 and be located at light
For light to be changed into the collimation unit 2 for column straightline propagation on 1 direction of illumination of source；Camera lens module include imaging unit 4,
Lens unit for object being observed amplification to be imaged.Wherein, dimming unit 6 is located at the front end of lens unit 5.
Using non-spherical lens attached drawing referring to Fig. 2 a, c and Fig. 3 a, c；Using the attached drawing of planoconvex spotlight referring to Fig. 2
B, d and Fig. 3 b, d.
Using pellicle mirror attached drawing referring to Fig. 2 c, d and Fig. 3 c, d；Using unpolarized optical splitter attached drawing referring to Fig. 2's
A, a, b of b and Fig. 3.
Further, dimming unit 6 is 1/4 wavelength plate or 1/4 phase difference film, be may be implemented incident linearly polarized light
It is adjusted to the clearer circularly polarized light of the stronger imaging effect of penetration power.Wherein, preferably 1/4 phase difference film.1/4 phase difference film is also known as
For 1/4 polymer phase retardation film, there is a kind of birefringent polymer piece that height is durable to make, the inclined of transmitted light can be changed
It shakes state, has the function of 1/4 wavelength plate, while 1/4 phase difference film is durable and cheap, greatly enhance tieing up for equipment
Shield property and reduce cost.Comparison situation referring in particular to table 1 about 1/4 wavelength plate and 1/4 phase difference film.
1 1/4 wavelength plate of table or each parameter of 1/4 phase difference film compare situation
| 1/4 wavelength plate | 1/4 phase difference film | |
| Material shape | It is round | It is rectangular |
| Material area [mm] | 76.2 (diameters) | 100×100 |
| Material | Crystal | Birefringent polymer |
| Transmitance | >98% | >90% |
| Thickness [mm] | 9 | 0.075 |
| Price | $16462.5 | $142.5 |
As shown in Table 1, in the case where ensureing that imaging effect is not much different, the price of 1/4 phase difference film is well below 1/4
Therefore the price of wavelength plate can substantially reduce maintenance and the use cost of the present apparatus using 1/4 phase difference film.On the other hand,
1/4 phase difference film is almost without thickness, and the thickness of 1/4 wavelength plate nearly 1cm, and the effect of present apparatus front end is mounted on for it
For fruit and 1/4 phase difference film is better than 1/4 wavelength plate.
Further, collimation unit 2 is non-spherical lens or planoconvex spotlight.Non-spherical lens is that double glued achromatisms are saturating
Mirror, includes the concave-convex lens and lenticular lens set gradually along light source direction of illumination, and the radius of curvature of lenticular lens is small
In the radius of curvature of concave-convex lens；Planoconvex spotlight is plane and convex surface on light source direction of illumination；Due to double glued achromatisms
Lens are small relative to the spherical aberration of planoconvex spotlight, realize that light alignment precision is high, therefore preferably double glued achromatic lens.
Further, spectrophotometric unit 3 is pellicle mirror or unpolarized optical splitter.Pellicle mirror all has with unpolarized optical splitter
The function of light splitting realizes that the fractional transmission of light, part reflect.Wherein, pellicle mirror is lamelliform eyeglass, and unpolarized point
Light device is cubic shaped；And for price, the price of unpolarized optical splitter needs many thousands of member, and because of body when installation
The larger installation of product is inconvenient, furthermore, unpolarized optical splitter is easily damaged, and influences imaging effect with larger refractive index, because
This, preferred pellicle mirror.
Further, the side of spectrophotometric unit 3 is provided with the barn door 7 for blocking the light through spectrophotometric unit.Herein
Barn door 7 is mainly the eyes for preventing laser from accidentally taking in human body, causes the damage of eyes.On the other hand, laser has centainly
Energy will not be irradiated on other instrument although the laser used for low-power laser, will not cause thermal sensation and cause instrument
Damage.But no matter laser whether there is nocuity, for the safty in use, it is necessary to carry out shading treatment to it.
Further, lens unit 5 is micro objective or Varifocal zoom lens.
Micro objective includes limited remote correction microcobjective and infinity correction microcobjective, has very high optics
Resolution ratio can be realized to being observed object parts macrostructure and internal microstructure, as haemocyte and microvascular endothelial are thin
The blur-free imaging of born of the same parents, but enlargement ratio is fixed, it is unadjustable.
Varifocal zoom lens are can to adjust amplification factor to realize the camera lens for being enlarged and reducing to observation scope, not only
The observation of macrostructure can be carried out to object being observed, can also carry out internal microstructure, such as haemocyte to object being observed
With the blur-free imaging of vascular endothelial cell, but optical resolution is relatively low relative to microcobjective.
Selective use can be carried out to microcobjective and Varifocal zoom lens according to the use purpose and use scope of device.
Such as both need to count the capilary distribution density in wide area, it is also desirable to observe haemocyte and flow feelings to blood flow
When condition is analyzed, Varifocal zoom lens are used；It only needs to be observed internal blood vessel haemocyte and vascular endothelial cell, and right
When image quality is more demanding, microcobjective is used.
Further, light source 1 is the LED or semiconductor laser for the plating polarizing coating that can send out linearly polarized light.Many institutes
Known, the light that LED is sent out is non-polarized light, circularly polarized light is converted in order to make LED pass through dimming unit, in LED illumination regions
Polarizing film is plated on surface, and the light that LED is sent out first passes through polarizing film, becomes polarised light.Use the excellent of the LED for plating polarizing coating
Point is that LED service lifes are long, and irradiation is uniform, is not in speckle noise.Disadvantage is poor for the light straightline propagation that it sends out.Cause
This, preferably semiconductor laser, semiconductor laser and collimation unit 2 form light source module, and the laser of outgoing is collimation
Laser is still with forms of radiation in spatial although the emergent light of semiconductor laser is line light, therefore, is needed
To place collimation unit in the position of emergent light becomes column straightline propagation by the propagation of laser.Optical maser wavelength is in 400-600
Between nanometer.
Further, imaging unit is allowed to for focus lighting into lens unit and receiving the imaging light of lens unit
For blur-free imaging in imaging unit, imaging unit is double glued achromatic lens, is made of concave-convex lens and lenticular lens, concave-convex
The position of lens and lenticular lens can be interchanged, such as concave-convex lens and two-sided convex lens are set gradually along light source direction of illumination
Mirror, or set gradually lenticular lens and concave-convex lens along light source direction of illumination.This is to reduce due to minute surface song
Rate and the error for causing refractive index, improve the alignment precision of emergent light.It is bonded by optical adhesive between the lens of two sides.
Further, the outside of light source module, spectrophotometric unit 3, camera lens module, polarization plates 8 and imaging module, which is equipped with, fixes
Frame 10.By fixed frame 10, entire optical instrument is formed a whole, and since selected device volume is smaller, it can
It is easy to operate and use whole device is arranged to handheld device.
The polarization plates used in the present apparatus have high extinction ratio for nano-particle linear membrane's polarization plates.Due to close
The progress of year technology, the signal-to-noise ratio of cmos sensor are also promoted, and match in excellence or beauty ccd sensor, and cheap, therefore the present apparatus
It is middle that previous ccd sensor is replaced using cmos sensor, achieve the purpose that reduce cost.
As Fig. 3 light schematic diagram it is found that the collimated unit of the line light sent out by light source 12 to be transformed into column straight
Linear light.Collimated incident light is irradiated on spectrophotometric unit 3, and the light of vertical polarization is split the reflection of unit 3, be irradiated to by
In the camera lens module that imaging unit 4, lens unit 5 and dimming unit 6 form, after perpendicular linear polarization light is by dimming unit 6
As circularly polarized light and be irradiated on human skin, due to circularly polarized light than linearly polarized light have better transmission capacity and at
Image sharpness, therefore the present apparatus has better imaging performance than previous imaging device.The circularly polarized light being irradiated on skin
It is divided into two kinds, one is the circular polarization reflected light being reflected back with original polarization state, another kind is by capilary hair inside skin
The unpolarized scattering light of raw scattering.Circular polarization reflected light is orthogonal again by the formation of dimming unit 6 with incident polarization direction
Parallel lines polarized reflection light, non-inclined scattering light form the random random circular polarization in direction of rotation by dimming unit 6 and scatter light.This
Two kinds of light are imaged by camera lens module, and are irradiated in polarization plates 8 by spectrophotometric unit 3.Here the polarization direction of polarization plates 8
It is orthogonal with parallel lines polarized reflection light, therefore the reflected light of skin surface can be filtered out, and in random circular polarization scattering light
Ingredient with vertical polarization, therefore image can be presented in imaging module by polarization plates 8.
Embodiment 2
As different from Example 1, as shown in Figure 4,5, dimming unit 6 is between imaging unit 4 and lens unit 5.
Remaining is the same as embodiment 1.
Using non-spherical lens attached drawing referring to Fig. 4 a, c and Fig. 5 a, c；Using the attached drawing of planoconvex spotlight referring to Fig. 4
B, d and Fig. 5 b, d.
Using pellicle mirror attached drawing referring to Fig. 4 c, d and Fig. 5 c, d；Using unpolarized optical splitter attached drawing referring to Fig. 4's
A, a, b of b and Fig. 5.Moving towards for light is same as Example 1.
Embodiment 3
As different from Example 1, as shown in Figure 6,7, dimming unit position 6 is between spectrophotometric unit and imaging unit.Its
Remaining same embodiment 1.
Using non-spherical lens attached drawing referring to Fig. 6 a, c and Fig. 7 a, c；Using the attached drawing of planoconvex spotlight referring to Fig. 6
B, d and Fig. 7 b, d.
Using pellicle mirror attached drawing referring to Fig. 6 c, d and Fig. 7 c, d；Using unpolarized optical splitter attached drawing referring to Fig. 6's
A, a, b of b and Fig. 7.Moving towards for light is same as Example 1.
Embodiment 4
As different from Example 1, as shown in Figure 8,9, right angle is equipped between collimation unit 2 and spectrophotometric unit 3 to reflect
Plane mirror 11 carrys out reflection source, can be parallel with the direction of imaging module by the direction of light source so that whole equipment is compacter.
Using non-spherical lens attached drawing referring to Fig. 8 a, c and Fig. 9 a, c；Using the attached drawing of planoconvex spotlight referring to Fig. 8
B, d and Fig. 9 b, d.
Using pellicle mirror attached drawing referring to Fig. 8 c, d and Fig. 9 c, d；Using unpolarized optical splitter attached drawing referring to Fig. 8's
A, a, b of b and Fig. 9.
Light schematic diagram as shown in Figure 9 is it is found that the collimated unit of the line light sent out by light source 2 is transformed into column
Line light.Collimated incident light is reflected by right angle plane of reflection mirror 11, then is irradiated on spectrophotometric unit 3, subsequent light
It is same as Example 1.
Embodiment 5
As different from Example 2, as shown in Figure 10,11, it is anti-that right angle is equipped between collimation unit 2 and spectrophotometric unit 3
It penetrates plane mirror 11 and carrys out reflection source, it can be parallel with the direction of imaging module by the direction of light source so that whole equipment is compacter.
Using non-spherical lens attached drawing referring to Figure 10 a, c and Figure 11 a, c；Using the attached drawing of planoconvex spotlight referring to figure
B, d of 10 b, d and Figure 11.
Using pellicle mirror attached drawing referring to Figure 10 c, d and Figure 11 c, d；Using unpolarized optical splitter attached drawing referring to Figure 10
A, b and Figure 11 a, b.
Light schematic diagram as shown in figure 11 is it is found that the collimated unit of the line light sent out by light source 2 is transformed into column
Shape line light.Collimated incident light is reflected by right angle plane of reflection mirror 11, then is irradiated to and is in charge of on unit 3, subsequent light
Line is same as Example 1.
Embodiment 6
As different from Example 3, as shown in Figure 12,13, it is anti-that right angle is equipped between collimation unit 2 and spectrophotometric unit 3
It penetrates plane mirror 11 and carrys out reflection source, it can be parallel with the direction of imaging module by the direction of light source so that whole equipment is compacter.
Using non-spherical lens attached drawing referring to Figure 12 a, c and Figure 13 a, c；Using the attached drawing of planoconvex spotlight referring to figure
B, d of 12 b, d and Figure 13.
Using pellicle mirror attached drawing referring to Figure 12 c, d and Figure 13 c, d；Using unpolarized optical splitter attached drawing referring to Figure 12
A, b and Figure 13 a, b.
Light schematic diagram is it is found that the collimated unit of the line light sent out by light source 2 is transformed into column as shown in fig. 13 that
Shape line light.Collimated incident light is reflected by right angle plane of reflection mirror 11, then is irradiated to and is in charge of on unit 3, subsequent light
Line is same as Example 1.
Claims (10)
1. a kind of device using circular polarization spectrum imaging detection human microvascular ultra microstructure, it is characterised in that：It includes at least
Light source module, spectrophotometric unit (3), camera lens module, polarization plates (8) and imaging module (9)；
The light source module includes light source (1) and is used to change into light for column straight-line transmitting on light source (1) direction of illumination
The collimation unit (2) broadcast；
The camera lens module includes imaging unit (4), for object being observed to be amplified the lens unit (5) being imaged and is used for
Linearly polarized light is modulated into the dimming unit (6) of circularly polarized light；
The imaging module (9) is digital camera.
2. the device according to claim 1 using circular polarization spectrum imaging detection human microvascular ultra microstructure, special
Sign is：The dimming unit (6) be located between spectrophotometric unit (3) and imaging unit (4) or positioned at imaging unit (4) with
Front end between lens unit (5) or positioned at lens unit (5).
3. the device according to claim 1 or 2 using circular polarization spectrum imaging detection human microvascular ultra microstructure,
It is characterized in that：The dimming unit (6) is 1/4 wavelength plate or 1/4 phase difference film.
4. the device according to claim 1 using circular polarization spectrum imaging detection human microvascular ultra microstructure, special
Sign is：The collimation unit (2) is non-spherical lens or planoconvex spotlight.
5. the device according to claim 1 using circular polarization spectrum imaging detection human microvascular ultra microstructure, special
Sign is：The spectrophotometric unit (3) is pellicle mirror or unpolarized optical splitter.
6. the device of circular polarization spectrum imaging detection human microvascular ultra microstructure is utilized according to claim 1 or 5,
It is characterized in that：The side of the spectrophotometric unit (3) is provided with the barn door (7) for blocking the light through spectrophotometric unit (3).
7. the device according to claim 1 using circular polarization spectrum imaging detection human microvascular ultra microstructure, special
Sign is：The lens unit (5) is micro objective or Varifocal zoom lens.
8. the device according to claim 1 using circular polarization spectrum imaging detection human microvascular ultra microstructure, special
Sign is：The light source (1) is the LED or semiconductor laser for the plating polarizing coating that can send out linearly polarized light.
9. the device according to claim 1 or 4 using circular polarization spectrum imaging detection human microvascular ultra microstructure,
It is characterized in that：Right angle plane of reflection mirror (11) is equipped between the collimation unit (2) and spectrophotometric unit (3).
10. the device according to claim 1 using circular polarization spectrum imaging detection human microvascular ultra microstructure, special
Sign is：The light source module, spectrophotometric unit (3), camera lens module, polarization plates (8) and imaging module outside be equipped with fixed frame
Frame (10).
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| Application Number | Priority Date | Filing Date | Title |
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| CN201720091550.8U CN207613764U (en) | 2017-01-24 | 2017-01-24 | Device for detecting human body microvascular ultrastructure by circular polarization spectrum imaging |
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