CN207379798U - Magnetic separating device and in-vitro diagnosis equipment - Google Patents
Magnetic separating device and in-vitro diagnosis equipment Download PDFInfo
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- CN207379798U CN207379798U CN201720374806.6U CN201720374806U CN207379798U CN 207379798 U CN207379798 U CN 207379798U CN 201720374806 U CN201720374806 U CN 201720374806U CN 207379798 U CN207379798 U CN 207379798U
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- reaction cup
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Abstract
The utility model discloses a kind of magnetic separating device and in-vitro diagnosis equipment, magnetic separating device includes the transhipment disk of carrying reaction cup；The magnetic separating device further includes：Heat the secondary heater of the primary heater of reaction cup and/or the cleaning solution of heating cleaning reaction cup.Magnetic separating device disclosed in the utility model, by adding the primary heater of heating reaction cup and/or heating the secondary heater of cleaning solution, the sample in reaction cup and reagent can be made to be in required reaction temperature during Magneto separate, beneficial to the combination of measured matter and magnetic bead, the complete reagent of unreacted and sample can relay continuous react in magnetic separating device in storehouse is incubated, the measured matter not combined with magnetic bead is effectively reduced or even avoids to be cleaned out, so as to improve Magneto separate effect, and then improve the reliability of testing result.
Description
Technical field
The utility model is related to vitro diagnostic techniques field, examine more specifically to a kind of magnetic separating device and in vitro
Disconnected equipment.
Background technology
In in-vitro diagnosis field, sample and reagent are generally positioned in reaction cup and are reacted, due to sample and reagent
Reaction needs isoperibol, and reaction cup is generally positioned in the incubation storehouse for providing isoperibol.Sample and reagent in reaction cup
After the reaction was complete in incubation storehouse, reaction cup is transported to magnetic separating device and carries out cleaning separation.
At present, the temperature of magnetic separating device is less than the temperature being incubated in storehouse, and the two differs greatly.Sample and reagent are being incubated
It educates there are the complete situation of unreacted in storehouse, if the sample and reagent unreacted in reaction cup are just transported to Magneto separate dress completely
It puts, temperature suddenly change, the reaction of sample and reagent in magnetic separating device can be influenced, the measured matter not combined with magnetic bead will
It is cleaned out so that Magneto separate effect is poor, and testing result is caused deviation occur, and the reliability of testing result is poor.
In addition, it is necessary to inject cleaning solution into reaction cup when magnetic separating device cleans the magnetic bead in reaction cup.By
The temperature of liquid is inconsistent in the temperature and reaction cup of cleaning solution, and usual cleaning solution temperature is less than the liquid temperature in reaction cup
Degree, causes the temperature of liquid in reaction cup cannot be maintained under the reaction temperature of demand, influences sample and reagent in reaction cup
Reaction, causes Magneto separate effect poor, the reliability for causing testing result is poor.
It is current people in the art to improve the reliability of testing result in conclusion how to improve Magneto separate effect
Member's urgent problem to be solved.
The content of the invention
In view of this, the purpose of this utility model is to provide a kind of magnetic separating device, improves Magneto separate effect, to improve inspection
Survey the reliability of result.The another object of the utility model is to provide a kind of in-vitro diagnosis with above-mentioned magnetic separating device and sets
It is standby.
In order to achieve the above object, the utility model provides following technical solution：
A kind of magnetic separating device includes the transhipment disk of carrying reaction cup；
The magnetic separating device further includes：The primary heater and/or heating for heating the reaction cup clean the reaction
The secondary heater of the cleaning solution of cup.
Preferably, when the magnetic separating device includes the primary heater, the primary heater includes：Matrix, if
The first heating element being placed in described matrix.
Preferably, described matrix is annular in shape, and described matrix is equipped with to accommodate the holding tank of the reaction cup, the base
The section of body radially is U-shaped.
Preferably, first heating element is located at the inner wall or outer wall of described matrix；
The primary heater further includes：The first thermal insulation barriers of first heating element are covered, cover described matrix
Second thermal insulation barriers of exposed part.
Preferably, the magnetic separating device further includes：It is tightly connected with described matrix and forms the end cap for holding storehouse, it is described anti-
Cup is answered to be located in the appearance storehouse, and the end cap has the through hole that injection needle and aspirating needle for the magnetic separating device pass through.
Preferably, when the magnetic separating device includes the secondary heater, the secondary heater includes：Housing, position
In in the housing and for the heat exchanger tube of cleaning solution flowing, in the housing and the heating heat exchanger tube second plus
Thermal element；
Wherein, the housing has the cleaning solution import connected with the heat exchanger tube and rinse liquid outlet, the cleaning solution
Outlet is connected with the injection needle of the magnetic separating device.
Preferably, the housing is equipped with helicla flute, and the heat exchanger tube is laid with along the helicla flute.
Preferably, second heating element is arranged at the middle part of the housing, and the helicla flute is located at described second
The periphery of heating element.
Preferably, the housing has central through hole, and the helicla flute is arranged on the outer wall of the housing, the housing
Top is equipped with guiding groove, and the guiding groove is connected with the helicla flute, and the bottom of the housing is equipped with to be connected with the helicla flute
And for the guiding port of heat exchanger tube extraction.
Preferably, the secondary heater further includes the insulating assembly for covering the housing outer surface；The insulating assembly
Including：The heat-insulated upper cover being connected with the housing tip, the heat insulation pedestal being connected with the housing bottom cover the housing week
Sideways 3rd thermal insulation barriers.
Preferably, when the magnetic separating device includes the secondary heater, the amount of liquid storage of the secondary heater is more than
The reservoir quantity of the injection needle.
Preferably, when the magnetic separating device includes the primary heater, the primary heater is mounted on the magnetic
In the support base of separator；
When the magnetic separating device includes the secondary heater, the secondary heater is arranged at the magnetic separating device
Fluid injection plate on, the fluid injection plate is provided with injection needle.
Preferably, when the magnetic separating device includes the primary heater, the magnetic separating device further includes：Detection institute
The first temperature sensor of the heating temperature of primary heater is stated, according to the heating and temperature control of the primary heater
First controller of the heating power of one heater, the heating temperature for preventing primary heater are more than the overheat protector of preset temperature
Part；
When the magnetic separating device includes the secondary heater, the magnetic separating device further includes：It is described for detecting
The second temperature sensor of the heating temperature of secondary heater, second according to the heating and temperature control of the secondary heater
The second controller of the heating power of heater.
Based on the magnetic separating device of above-mentioned offer, the utility model additionally provides a kind of in-vitro diagnosis equipment, this is examined in vitro
Disconnected equipment includes magnetic separating device, and the magnetic separating device is the magnetic separating device described in above-mentioned any one.
Magnetic separating device provided by the utility model is clear by the primary heater and/or heating of adding heating reaction cup
The secondary heater of washing lotion can make the sample in reaction cup and reagent be in required reaction temperature during Magneto separate,
Beneficial to the combination of measured matter and magnetic bead, the complete reagent of unreacted and sample can continue in magnetic separating device in storehouse is incubated
It reacts, effectively reduces or even avoid the measured matter not combined with magnetic bead and be cleaned out, so as to improve Magneto separate
Effect, and then improve the reliability of testing result.
Description of the drawings
It, below will be to embodiment or the prior art in order to illustrate more clearly of the technical scheme in the embodiment of the utility model
Attached drawing is briefly described needed in description, it should be apparent that, the accompanying drawings in the following description is only that this practicality is new
The embodiment of type, for those of ordinary skill in the art, without creative efforts, can also be according to carrying
The attached drawing of confession obtains other attached drawings.
Fig. 1 provides the structure diagram of magnetic separating device for the utility model embodiment；
Fig. 2 provides the part-structure schematic diagram of magnetic separating device for the utility model embodiment；
Fig. 3 provides the structure diagram of primary heater in magnetic separating device for the utility model embodiment；
Fig. 4 provides the structure diagram of secondary heater in magnetic separating device for the utility model embodiment；
Fig. 5 provides the part-structure schematic diagram of secondary heater in magnetic separating device for the utility model embodiment.
Specific embodiment
The following is a combination of the drawings in the embodiments of the present utility model, and the technical scheme in the embodiment of the utility model is carried out
It clearly and completely describes, it is clear that the described embodiments are only a part of the embodiments of the utility model rather than whole
Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are without making creative work
All other embodiments obtained shall fall within the protection scope of the present invention.
As shown in Figs. 1-5, the magnetic separating device that the utility model embodiment provides includes the transhipment disk of carrying reaction cup 9
10.Above-mentioned magnetic separating device further includes：Heat the primary heater 3 of reaction cup 9 and/or the cleaning solution of heating cleaning reaction cup 9
Secondary heater 6.
When above-mentioned magnetic separating device include primary heater 3 when, into magnetic separating device reaction cup 9 by primary heater
3 heating so that sample and reagent in reaction cup 9 are heated, so that the sample and reagent in reaction cup 9 reach required anti-
Answer temperature；When above-mentioned magnetic separating device includes secondary heater 6, secondary heater 6 heats cleaning solution, is noted into reaction cup 9
After entering cleaning solution, sample and reagent in reaction cup 9 are heated, so that the sample and reagent in reaction cup 9 reach required anti-
Answer temperature.
The utility model embodiment provide magnetic separating device, by add heating reaction cup 9 primary heater 3 and/
Or the secondary heater 6 of heating cleaning solution, sample in reaction cup 9 and reagent can be made required during Magneto separate
Reaction temperature, beneficial to the combination of measured matter and magnetic bead, the complete reagent of unreacted and sample can be in Magneto separates in storehouse is incubated
Device relaying is continuous to react, and effectively reduces or even avoids the measured matter not combined with magnetic bead and be cleaned out, so as to carry
High Magneto separate effect, and then improve the reliability of testing result.
In above-mentioned magnetic separating device, it is designed according to actual needs for the concrete structure of primary heater 3.For side
Just install, above-mentioned primary heater 3 includes：Matrix 31, the first heating element 32 being arranged on matrix 31.Certainly, it is also optional
Selecting above-mentioned primary heater 3 only includes the first heating element 32, it is not limited to the above situation.
In order to improve the efficiency of heating surface, reduce cost, above-mentioned matrix 31 is Al-alloy parts.Certainly, matrix 31 also may be selected is
The preferable material of other heat transfer efficiencies, it is not limited to this.
Can be solid panel or ring-type for the shape of matrix 31.In order to facilitate the installation of, above-mentioned matrix 31 is in ring
Shape, and matrix 31 is equipped with to accommodate the holding tank 311 of reaction cup 9.So, it is possible to increase reaction cup 9 and the contact surface of matrix 31
Product, so as to increase heating surface (area) (HS, improves the efficiency of heating surface.
It is understood that the rotation axis 8 of the hollow space ribbon supply turn fortune disk 10 of matrix 31 passes through.
In order to simplify structure and convenient for heating reaction cup 9, the section of above-mentioned matrix 31 radially is U-shaped.It needs to illustrate
, along the axially vertical of the section of 31 radial direction of matrix and matrix 31.Certainly, matrix 31 also may be selected is shape, is not limited to
In above-described embodiment.
For the relative position of 31 and first heating element 32 of matrix, also make choice according to actual needs.For convenience
Installation, above-mentioned first heating element 32 are located at the inner wall or outer wall of matrix 31.Certainly, the first heating element 32 also may be selected to be located at
The inside of matrix 31, but manufacture complex.
In order to avoid heat scatters and disappears, the efficiency of heating surface is improved, above-mentioned primary heater 3 further includes：Cover the first heating element
32 the first thermal insulation barriers 33 cover the second thermal insulation barriers of the exposed part of matrix 31.
Specifically, when the first heating element 32 is located at the inner wall of matrix 31, the exposed part of matrix 31 is matrix 31
Outer wall（Bottom wall, roof and axial side wall）；When the first heating element 32 is located at the outer wall of matrix 31（Bottom wall, roof and axial side
Wall）When, the exposed part of matrix 31 is the inner wall of matrix 31.
For the type of the first thermal insulation barriers 33 and the second thermal insulation barriers, make choice according to actual needs, such as first heat-insulated
33 and second thermal insulation barriers of part are insulating foam or thermal insulation board etc..For the concrete type and structure of the first heating element 32, also
It makes choice according to actual needs, such as the first heating element 32 is heating resistor film or heating tube etc..
Above-mentioned primary heater 3 can be also heat exchanger structure, be not limited solely to the structure of above-described embodiment offer.
Reaction cup 9 on transhipment disk 10 is moved to behind setting position, it is necessary to be operated.For the ease of detecting transhipment disk
Reaction cup 9 on 10 moves to setting position, and above-mentioned matrix, which is equipped with, resets photoelectric sensor 101, and it is anti-that transhipment disk 10 is equipped with placement
The putting hole of cup 9 is answered, the edge of transhipment disk 10, which is equipped with, to be used cooperatively with reset photoelectric sensor 101 and corresponded with putting hole
Reset groove.
In above-mentioned magnetic separating device, detected when one on transhipment disk 10 resets the groove photoelectric sensor 101 that is reset,
Show that reaction cup 9 corresponding with the reset groove moves to setting position, you can operated.
When transhipment disk 10 is above-mentioned has reaction cup 9, unlatching magnetic separating device is just significant, in order to avoid magnetic separating device
It opens by mistake or other maloperations, above-mentioned matrix 31 is equipped with reflective photoelectric sensor 102, the reflective photoelectric sensor 102
Reaction cup 9 with transporting 10 initial position of disk is used cooperatively.
It should be noted that reflective photoelectric sensor 102 is one, turn when reflective photoelectric sensor 102 detects
When the initial bit of fortune disk 10 is equipped with reaction cup 9, showing to transport has reaction cup 9 on disk 10, you can driving transhipment disk 10 moves, right
Reaction cup 9 is operated accordingly.When reaction cup 9 is not detected in reflective photoelectric sensor 102, show that the initial position does not have
There is reaction cup 9, then transhipment disk 10 is not driven to rotate.
For the ease of installing reflective photoelectric sensor 102, the outer wall of above-mentioned matrix 31 is higher than the inner wall of matrix 31, transhipment
Disk 10 is located between the outer wall top of matrix 31 and the inner wall top of matrix 31.
, it is necessary to the magnetic bead and mixing reaction cup 9 of 104 adsorption reaction cup 9 of magnet during Magneto separate.For the ease of realizing
Above-mentioned function, the circumferential side plate of above-mentioned matrix 31 are equipped with magnet 104, and matrix 31 is equipped with the rotor 21 being used for for evenly mixing device 2
What is risen allows bit architecture, to ensure that rotor 21 rises the outer outside for being sleeved on reaction cup 9.
In order to reinforce magnet 104, the magnet locating piece 103 of phase magnet 104 is additionally provided on above-mentioned matrix 31.
Preferably, above-mentioned magnet 104 is ndfeb magnet, and magnet locating piece 103 is sheet metal component.Certainly, magnetic also may be selected
Iron 104, magnet locating piece 103 are other types, it is not limited to above-described embodiment.
For the size and number of resigning groove, it is designed according to the size and number of rotor 21.Preferably, step down recessed
Slot is three.
In above-mentioned magnetic separating device, for the reaction in ectocine reaction cup 9, above-mentioned magnetic separating device further includes end cap
4, which, which is tightly connected and is formed with matrix 31, holds storehouse, and reaction cup 9, which is located at, to be held in storehouse, so so that reaction cup 9 is in phase
To in the environment of sealing.In addition, the end cap 4 has the through hole that injection needle 5 and aspirating needle for magnetic separating device pass through, to ensure
The imbibition in fluid injection and aspirating needle autoreaction cup 9 into reaction cup 9 of injection needle 5.
For the concrete structure of secondary heater 6, design can be also made choice according to actual needs.Preferably, above-mentioned
Two heaters 6 include：Housing 64, in housing 64 and for the heat exchanger tube of cleaning solution flowing, in housing 64 and heating is changed
Second heating element 62 of heat pipe.
It is understood that the second heating element 62 heats heat exchanger tube, heat exchanger tube can be directly heated, can also pass through housing 64
Indirectly heat heat exchanger tube.
Above-mentioned housing 64 has the cleaning solution import 66 that connect with heat exchanger tube and a rinse liquid outlet 67, rinse liquid outlet 67 and
The injection needle 5 of magnetic separating device connects.
The number of above-mentioned rinse liquid outlet 67 is identical with the number of injection needle 5 and corresponds.Preferably, rinse liquid outlet
67 at least two, and along the circumferentially distributed of housing 64.For the ease of connection, above-mentioned cleaning solution import 66 is equipped with inlet pipe, above-mentioned
Rinse liquid outlet 67 is equipped with outlet pipe.For the ease of positioning, above-mentioned inlet pipe is fixed using the card slot on housing 64.
For the type and shape of 64 and second heating element 62 of housing, make choice according to actual needs.It is for example, above-mentioned
Housing 64 is cylindrical shape, and above-mentioned second heating element 62 is heating resistor film or heating tube etc..For the material of heat exchanger tube, selection
Heat transfer efficiency is higher and inert material that do not react with cleaning solution makes.To the material of housing 64, also according to actual needs
It makes choice, in order to improve the efficiency of heating surface, reduce cost, preferably selects housing 64 as Al-alloy parts or ironware.
In above-mentioned secondary heater 6, the second heating element 62 by heated shell 64 come heat heat exchanger tube or second plus
Thermal element 62 directly heats heat exchanger tube or the second heating element of part 62 heats heat exchanger tube, part by heated shell 64
Second heating element 62 directly heats heat exchanger tube.It will be apparent that the heated effect length efficiency of heating surface of heating tube.
It is heated length to increase heat exchanger tube contact with housing 64, while reduces the volume of entire secondary heater 6, on
Housing 64 is stated equipped with helicla flute 643, heat exchanger tube is laid with along helicla flute.
Above-mentioned helicla flute 643 may be provided at the inner wall of housing 64, may also be arranged on the outer wall of housing 64.For the ease of installation
Heat exchanger tube, above-mentioned helicla flute 643 are arranged on the outer wall of housing 64.
Further, above-mentioned housing 64 has central through hole 641, and the top of housing 64 is equipped with guiding groove 642, the guiding groove
642 connect with helicla flute 643, and the bottom of housing 64 is equipped with the guiding port 644 for connecting and supplying heat exchanger tube to draw with helicla flute 643,
As shown in Figure 5.
The installation method of above-mentioned heat exchanger tube is：Heat exchanger tube is from the bottom of housing 64 through central through hole 641, subsequently into drawing
Guide groove 642, and pass through guiding groove 642 and enter helicla flute 643, and be laid with along helicla flute 643, when heat exchanger tube reaches guiding port 644
Afterwards, by heat exchanger tube throw out spiral slot 643, then the installation of heat exchanger tube is completed.
It should be noted that heat exchanger tube is corresponded with injection needle 8, and when heat exchanger tube at least two, 642 He of guiding groove
The helicla flute 643 communicated therewith corresponds, and guiding port 644 and the helicla flute 643 communicated therewith correspond, i.e. guiding groove
642nd, the number of guiding port 644 and helicla flute 643 is identical with the number of injection needle 8.
Certainly, above-mentioned helicla flute 643 also may be selected is other structures, it is not limited to embodiment.
Further, the second heating element 62 is arranged at the slot bottom of helicla flute.Certainly, the second heating element 62 also may be selected
Other positions are arranged at, such as the second heating element 62 is arranged at the middle part of housing 64, and helicla flute is located at the second heating element
62 periphery.At this point, the second heating element 62 transfers heat to housing 64, housing 64 transfers heat to heat exchanger tube, so as to
Heat cleaning solution.
In above-mentioned secondary heater, it is coiled pipe that heat exchanger tube, which also may be selected, i.e., with serpentine configuration stringing, it is not limited on
Spiral piping mode is stated, as long as ensureing heating effect.
In heating process, heat is easier to be diffused into the external world by housing 64 secondary heater 6, causes secondary heater 6
The efficiency of heating surface it is relatively low.In order to improve the efficiency of heating surface, above-mentioned secondary heater 6 further includes heat-insulated group of 64 outer surface of covering housing
Part.The insulating assembly can thermal insulation layer, can be also made of multiple heat insulating members.
For the ease of setting, above-mentioned insulating assembly includes：The heat-insulated upper cover 61 being connected with 64 top of housing, with 64 bottom of housing
The connected heat insulation pedestal 68 in end covers the 3rd thermal insulation barriers 65 of 64 peripheral side of housing.
Specifically, heat-insulated upper cover 61 and heat insulation pedestal 68 are heat-insulating shield, for heat-insulated upper cover 61 and heat insulation pedestal 68
Specific material, makes choice according to actual needs.Above-mentioned 3rd thermal insulation barriers 65 can be thermal insulation layer or collet, for the
The concrete type of three thermal insulation barriers 65, also according to actual needs into selection, such as the 3rd thermal insulation barriers 65 are insulating foam or heat-insulated
Plate.
For the ease of installing heat exchanger tube, above-mentioned heat insulation pedestal 68 is equipped with：Place the first of the cleaning solution import 66 of heat exchanger tube
Second placing groove 682 of the rinse liquid outlet 67 of placing groove 681 and placement heat exchanger tube.
Further, heat-insulated upper cover 61 and heat insulation pedestal 68 are tightly connected with housing 64, are further reduced outwardly
The heat of heat dissipation, further improves the efficiency of heating surface.
Certainly, secondary heater 6 also may be selected as other structures, such as the structures such as shell-and-tube heat exchanger, it is not limited to
Above-described embodiment.
The injection rate that injection needle 5 is injected in reaction cup 9 every time is pre-set, in order to ensure secondary heater 6
The efficiency of supply of the efficiency of heating surface and the cleaning solution of supply heating, the amount of liquid storage of above-mentioned secondary heater 6 are more than the note of injection needle 5
Liquid measure.Can with understanding, the reservoir quantity of injection needle 5 is a reservoir quantity of injection needle 5.
In above-mentioned magnetic separating device, secondary heater 6 preheats the cleaning solution squeezed into magnetic separating device, injection needle
After 5 fluid injections once, the extraction raffinate of storage makes newly to add in rapidly the cleaning solution heating in secondary heater 6 in secondary heater 6, shortens
Heating time improves efficiency of heating surface raising, also fully can meet the requirement of liquid temperature degree, improve efficiency of supply.
The difference of the reservoir quantity of amount of liquid storage and injection needle 5 for secondary heater 6, is designed according to actual needs,
Such as the amount of liquid storage of secondary heater 6 is twice or three times of the reservoir quantity of injection needle 5.
When above-mentioned magnetic separating device includes primary heater 3, for the ease of installing primary heater 3, prioritizing selection first
Heater 3 is mounted in the support base 1 of magnetic separating device.
Specifically, transhipment disk 10 drives rotation by rotation axis 8, and rotation axis 8 is fixed on by bearing 35 on bearing block 34, axis
Bearing 34 is mounted on support plinth 1, and rotation axis 8 runs through primary heater 3.
When above-mentioned magnetic separating device includes secondary heater 6, prioritizing selection secondary heater 6 is arranged at magnetic separating device
On fluid injection plate 7, fluid injection plate 7 is provided with injection needle 5.In this way, secondary heater 6 is moved with fluid injection plate 7, injection needle 5, it is convenient
Fluid injection；When the rinse liquid outlet 67 of above-mentioned secondary heater 6 is connected by pipeline with injection needle 5, cleaning solution is also shortened
Outlet 67 to injection needle interface distance, reduce because exposure in air due to the cleaning solution temperature drop that brings.
Above-mentioned primary heater 3 heats reaction cup 9, and for the ease of ensureing the temperature of reaction cup 9, above-mentioned magnetic separating device is also
Including：First temperature sensor and the first controller；Wherein, the heating temperature of the first temperature sensor detection primary heater 3；
First controller is according to the heating power of the heating and temperature control primary heater 3 of primary heater 3.
Above-mentioned magnetic separating device controls the heating power of primary heater 3 by the first controller, so as to fulfill to heating
The control of temperature, and then control the temperature of reagent and sample in reaction cup 9 and reaction cup 9, with ensure in reaction cup 9 reagent and
Sample is in required reaction temperature.
Specifically, when primary heater 3 includes matrix 31 and the first heating element 32, the heating temperature of primary heater 3
Degree can be the temperature of matrix 31.Certainly, the temperature of reaction cup 9 also can be directly detected, is added according to the temperature of reaction cup 9 control first
The heating power of hot device 3.
In order to avoid the excessively high damage equipment of temperature, above-mentioned magnetic separating device further includes overheat protector part, the overheat protector part
The heating temperature for preventing primary heater 3 is more than preset temperature.
For the specific location of the first controller, the first temperature sensor and overheat protector part, can according to actual needs into
Row selection, the position of usual above-mentioned three is away from the first heating element 32.For example, when the first heating element 32 is mounted on matrix 31
Inner wall when, the first controller, the first temperature sensor and overheat protector part be mounted on place of the matrix 31 in addition to inner wall, with
It avoids influencing accuracy of detection and control accuracy.
When above-mentioned secondary heater 6 heats cleaning solution, for the ease of ensureing the temperature in reaction cup 9, above-mentioned Magneto separate dress
It puts and further includes second temperature sensor 63 and second controller, wherein, second temperature sensor 63 is used to detect secondary heater 6
Heating temperature, second controller is according to the heating power of the heating and temperature control secondary heater 6 of the secondary heater 6.
Above-mentioned magnetic separating device controls the heating power of secondary heater 6 by second controller, so as to fulfill to heating
The control of temperature, and then the temperature of reagent and sample in reaction cup 9 is controlled, to ensure reagent in reaction cup 9 and sample in institute
In the reaction temperature needed.
Specifically, when secondary heater 6 includes：When housing 64, heat exchanger tube and the second heating element 62, secondary heater 6
Heating temperature can be housing 64 temperature or heat exchanger tube temperature.Certainly, the temperature of reaction cup 9, root also can directly be detected
According to the heating power of the temperature control secondary heater 6 of reaction cup 9.
Based on the magnetic separating device that above-described embodiment provides, the utility model embodiment additionally provides a kind of in-vitro diagnosis and sets
Standby, which includes magnetic separating device, which is the magnetic separating device described in above-described embodiment.
Since the magnetic separating device that above-described embodiment provides has above-mentioned technique effect, what the utility model embodiment provided
In-vitro diagnosis equipment has above-mentioned magnetic separating device, then the in-vitro diagnosis equipment that the utility model embodiment provides also has corresponding
Technique effect, repeat no more herein.
For the concrete type of in-vitro diagnosis equipment, can make choice according to actual needs, the utility model embodiment pair
This is not limited.
The foregoing description of the disclosed embodiments enables those skilled in the art to realize or using the utility model.
A variety of modifications of these embodiments will be apparent for a person skilled in the art, general original as defined herein
Reason can be realized in other embodiments without departing from the spirit or scope of the present utility model.Therefore, this practicality is new
Type is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase
Consistent most wide scope.
Claims (14)
1. a kind of magnetic separating device, including：Carry the transhipment disk of reaction cup, which is characterized in that the magnetic separating device further includes：
Heat the secondary heater of the primary heater of the reaction cup and/or the cleaning solution of the heating cleaning reaction cup；
When the magnetic separating device includes the primary heater, the magnetic separating device further includes：Detect first heating
First temperature sensor of the heating temperature of device, according to primary heater described in the heating and temperature control of the primary heater
First controller of heating power；
When the magnetic separating device includes the secondary heater, the magnetic separating device further includes：For detecting described second
The second temperature sensor of the heating temperature of heater, the second heating according to the heating and temperature control of the secondary heater
The second controller of the heating power of device.
2. magnetic separating device according to claim 1, which is characterized in that the magnetic separating device includes the described first heating
During device, the primary heater includes：Matrix, the first heating element being arranged in described matrix.
3. magnetic separating device according to claim 2, which is characterized in that described matrix is annular in shape, and described matrix is equipped with
For accommodating the holding tank of the reaction cup, the section of described matrix radially is U-shaped.
4. magnetic separating device according to claim 3, which is characterized in that first heating element is located at described matrix
Inner wall or outer wall；
The primary heater further includes：The first thermal insulation barriers of first heating element are covered, cover the exposed of described matrix
The second partial thermal insulation barriers.
5. magnetic separating device according to claim 3, which is characterized in that further include：With described matrix sealed connection and shape
The end cap of Cheng Rongcang, the reaction cup is located in the appearance storehouse, and the end cap has the injection needle for the magnetic separating device
The through hole passed through with aspirating needle.
6. magnetic separating device according to claim 1, which is characterized in that the magnetic separating device includes the described second heating
During device, the secondary heater includes：Housing, in the housing and for the heat exchanger tube of cleaning solution flowing, positioned at institute
It states in housing and heats the second heating element of the heat exchanger tube；
Wherein, the housing has the cleaning solution import connected with the heat exchanger tube and rinse liquid outlet, the rinse liquid outlet
It is connected with the injection needle of the magnetic separating device.
7. magnetic separating device according to claim 6, which is characterized in that the housing is equipped with helicla flute, the heat exchanger tube
It is laid with along the helicla flute.
8. magnetic separating device according to claim 7, which is characterized in that second heating element is arranged at the housing
Middle part, and the helicla flute is located at the periphery of second heating element.
9. magnetic separating device according to claim 7, which is characterized in that the housing has central through hole, the spiral
Slot is arranged on the outer wall of the housing, and the top of the housing is equipped with guiding groove, and the guiding groove is connected with the helicla flute, institute
The bottom for stating housing is equipped with the guiding port for connecting with the helicla flute and being drawn for the heat exchanger tube.
10. magnetic separating device according to claim 6, which is characterized in that the secondary heater is further included described in covering
The insulating assembly of housing outer surface；The insulating assembly includes：The heat-insulated upper cover being connected with the housing tip, with the housing
The heat insulation pedestal that bottom is connected covers the 3rd thermal insulation barriers of the housing peripheral side.
11. magnetic separating device according to claim 1, which is characterized in that the magnetic separating device includes described second and adds
During hot device, the amount of liquid storage of the secondary heater is more than the reservoir quantity of the injection needle of the magnetic separating device.
12. magnetic separating device according to claim 1, which is characterized in that
When the magnetic separating device includes the primary heater, the primary heater is mounted on the branch of the magnetic separating device
It supports on pedestal；
When the magnetic separating device includes the secondary heater, the secondary heater is arranged at the note of the magnetic separating device
On liquid plate, the fluid injection plate is provided with injection needle.
13. magnetic separating device according to claim 1, which is characterized in that
When the magnetic separating device includes the primary heater, the magnetic separating device further includes：Prevent primary heater
Heating temperature is more than the overheat protector part of preset temperature.
14. a kind of in-vitro diagnosis equipment, including magnetic separating device, which is characterized in that the magnetic separating device is such as claim
Magnetic separating device in 1-13 described in any one.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720374806.6U CN207379798U (en) | 2017-04-11 | 2017-04-11 | Magnetic separating device and in-vitro diagnosis equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110487998A (en) * | 2019-08-13 | 2019-11-22 | 迈克医疗电子有限公司 | Parameter optimization method and device, analysis instrument, the storage medium of magnetic separation system |
| CN110823669A (en) * | 2019-11-08 | 2020-02-21 | 广州科方生物技术股份有限公司 | Magnetic separation cleaning method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110487998A (en) * | 2019-08-13 | 2019-11-22 | 迈克医疗电子有限公司 | Parameter optimization method and device, analysis instrument, the storage medium of magnetic separation system |
| CN110823669A (en) * | 2019-11-08 | 2020-02-21 | 广州科方生物技术股份有限公司 | Magnetic separation cleaning method |
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