CN207138143U - A kind of bed spray device - Google Patents
A kind of bed spray device Download PDFInfo
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- CN207138143U CN207138143U CN201721343305.8U CN201721343305U CN207138143U CN 207138143 U CN207138143 U CN 207138143U CN 201721343305 U CN201721343305 U CN 201721343305U CN 207138143 U CN207138143 U CN 207138143U
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Abstract
The utility model discloses a kind of bed spray device, including two fluidic interfaces and a gas interface, fluid path, gas passage and nozzle；Described two fluidic interfaces are connected with the fluid path, and one gas interface is connected with the gas passage, and the fluid path intersects with the gas passage end and is connected with the nozzle.Compared with existing fluid bed spray gun, on the one hand the device can make two kinds of different liquid hydrojet simultaneously.On the other hand, in fluid bed granulation, when binder solution used is temperature sensitive, stops or terminate that cleaning fluid can be passed through at another fluidic interface in time during hydrojet, avoid spray nozzle clogging.Make fluid bed spray system cleaning process simply convenient.The utility model overcomes troublesome in poeration when needing to switch between two kinds of solution existing for existing spray gun, takes longer, while is also avoided that spray gun blocks, cleaning is difficult.
Description
Technical field
It the utility model is related to a kind of pharmaceutical granulation equipment, more particularly to a kind of bed spray device.
Background technology
Fluidized system has a variety of applications in pharmaceutical field.For example, can be with fluidized system to medicine system
Wet granular in agent is dried, and one-step palletizing is carried out to drug powder or micropill, slice, thin piece are coated.
Fluid-bed marumerization is fluid bed very important application in pharmaceutical field.Specifically by medicine powder
End is fitted into the product chambers of fluid bed, and drug powder keeps the fluidized state to suspend, bonding under airflow function from bottom to top
Agent liquid is sprayed into from top or bottom into fluid-bed chamber, makes drug powder assemble to form particle while dry, persistently the process
Until hydrojet and dry completion, particle is collected from product chambers.
In existing fluidized system, one spray gun of liquid-jet device generally use of binder solution.The structure of spray gun
For a fluidic interface and a gas interface, a fluid passage, a gas passage and a nozzle.Wherein fluidic interface
Binder solution is generally connect, gas interface generally connects compressed air, so that binder solution forms certain spray pattern spray
Particle is formed on to the material in fluid bed cavity.
A problem existing for these spray guns can not be realized when material needs while sprays two kinds of solution, or hydrojet mistake
Cheng Zhong, it is necessary to remove existing pipeline when spray gun needs to switch between two kinds of solution, new pipeline is being installed, it is troublesome in poeration, take
It is longer.
Another problem existing for existing spray gun is, when binder solution be affected by temperature it is larger, such as in the condition of high temperature
It is down liquid, when being solid-state under low-temperature condition, when spray gun stops spray binder solution, it is impossible to be passed through the cleaning of heating in time
Liquid, spray gun is caused to block, cleaning is difficult.
Utility model content
The technical problems to be solved in the utility model is to provide a kind of bed spray device, the spray of its three interface of band
Rifle, for switching fluid bed spray adhesive and cleaning two states at any time, overcome needs at two kinds existing for existing spray gun
It is troublesome in poeration when switching between solution, it is time-consuming longer, while also it is avoided that spray gun blocks, cleaning is difficult.
Technical scheme is used by the utility model solves its technical problem：
A kind of bed spray device, including two fluidic interfaces and a gas interface, fluid path, gas passage and
Nozzle；Described two fluidic interfaces are connected with the fluid path, and one gas interface is connected with the gas passage, institute
Fluid path is stated with the gas passage end to intersect and with the nozzle be connected.
As the preferable technical scheme of the utility model, a valve is respectively equipped with described two fluidic interfaces.
As the preferable technical scheme of the utility model, described two fluidic interfaces are pooled in fluid path and connect spray
Mouth, the gas interface are passed through in gas passage and liquid is formed spray pattern at nozzle.
As the preferable technical scheme of the utility model, the angle between described two fluidic interfaces is 30 ° -90 °, preferably
For 45 °；Angle between the gas interface and the either interface of described two fluidic interfaces is identical, is 30 ° -90 °, preferably
For 45 °；Angle between the gas interface and the gas passage is more than 90 degree.
As the preferable technical scheme of the utility model, described two fluidic interfaces are with the fluid path positioned at same flat
Face；The fluid path is located inside the gas passage；The liquid inlet of described two fluidic interfaces is located at the gas and led to
The outside on road.
It is identical as the preferable technical scheme of the utility model, the diameter of described two fluidic interfaces；Described two liquid
The diameter of interface is less than the diameter of the gas interface.Preferably, the diameter of the gas interface is at least the fluidic interface
2 times of diameter, the diameter range of the fluidic interface is 3.0mm-5.0mm, and the diameter range of the gas interface is 6.0mm-
10.0mm。
As the preferable technical scheme of the utility model, described two fluidic interfaces connect different liquid respectively；The gas
Body interface connects compressed air.
Compared with prior art, the beneficial effects of the utility model are：It the utility model is related to one kind and carry three interfaces
Sprayer unit.Compared with existing fluid bed spray gun, on the one hand the device can make two kinds of different liquid hydrojet simultaneously.Separately
On the one hand, in fluid bed granulation, when binder solution used is temperature sensitive, stop or terminate hydrojet when can
Cleaning fluid is passed through at another fluidic interface in time, avoids spray nozzle clogging.Make fluid bed spray system cleaning process simply convenient.
The utility model overcome needed existing for existing spray gun between two kinds of solution switch when it is troublesome in poeration, take it is longer, simultaneously
Also it is avoided that spray gun blocks, cleaning is difficult.
Brief description of the drawings
The utility model is further illustrated with reference to the accompanying drawings and examples.
Fig. 1 is a kind of top view of bed spray device of the utility model.
Fig. 2 is a kind of front view of bed spray device of the utility model.
Fig. 3 is a kind of rearview of bed spray device of the utility model.
Description of reference numerals is as follows in figure：
1 is the first fluidic interface, and 2 be second liquid interface, and 3 be gas interface, and 4 be fluid path, and 5 be gas passage, 6
It is nozzle, 7 be the first valve, and 8 be the second valve.
Embodiment
The utility model is described in further detail presently in connection with accompanying drawing.These accompanying drawings are simplified schematic diagram,
Only illustrate basic structure of the present utility model in a schematic way, therefore it only shows the composition relevant with the utility model.
As shown in figure 1, in the utility model fluid bed liquid-jet device, including such as lower part, two of which fluidic interface（The
One fluidic interface 1 and second liquid interface 2）, a gas interface 3, another part is fluid path 4 and gas passage 5, finally
A part is nozzle 6.Specific structure is two fluidic interfaces of liquid（First fluidic interface 1 and second liquid interface 2）Converge
Gather in fluid path 4 and connect the part of nozzle 6, gas interface 3, which connects gas passage 5 and converged at nozzle 6, makes liquid shape
Into spray pattern.
In liquid-jet device of the present utility model, two fluidic interfaces（First fluidic interface 1 and second liquid interface 2）Place
First valve 7 and the second valve 8 are set respectively, and controllable different solution enters in fluid path 4 and sprayed by nozzle 6.
The angle of first fluidic interface 1 and second liquid interface 2 is 30 ° to 90 °, preferably 45 °.The reason for being set to 45 ° is to facilitate two
Individual interface takes over road, at the same liquid when entering fluid path 4 as close possible to the straight angle, i.e. the first fluidic interface 1 and second liquid
Interface 2 is generally aligned in the same plane with fluid path 4（See Fig. 2 and Fig. 3）, liquid stream is smooth.Fluid path 4 is located inside gas passage 5,
Two fluidic interfaces（First fluidic interface 1 and second liquid interface 2）Liquid inlet be located at the outside of gas passage 5（See figure
1）.
In the utility model, as shown in Figures 2 and 3, two fluidic interfaces（First fluidic interface 1 and second liquid connect
Mouth 2）There is no particular/special requirement with the angle of gas interface 3, it is preferred that the angle and second of the first fluidic interface 1 and gas interface 3
Fluidic interface 2 is identical with the angle of gas interface 3, and angle is 30 ° to 90 °, preferably 45 °, it is determined as is convenient each the reason for 45 °
Interface takes over road, meanwhile, the angle between gas interface 3 and gas passage 5 is more than 90 degree（As shown in Figures 2 and 3）.Liquid connects
The diameter of mouth is less than the diameter of gas interface 3, can conveniently control solution flow rate, and two the first fluidic interfaces of fluidic interface 1
It is identical with the diameter of second liquid interface 2.The diameter of at least 2 times fluidic interfaces of the diameter of gas interface 3, fluidic interface it is straight
Footpath scope is 3.0mm-5.0mm, and the diameter range of gas interface 3 is 6.0mm-10.0mm.
Embodiment one：The application method of the utility model fluid bed liquid-jet device
The adhesive used in fluid bed granulation is 50 degrees Celsius of gelatin solution.
Before fluidized bed granulation starts, the first fluidic interface 1 and second liquid interface 2 are connect to 50 degrees Celsius of gelatin respectively
Solution and 50 degrees Celsius of hot water, gas interface 3 are connected in compressed air.The valve of gelatin solution and hot water（The He of first valve 7
Second valve 8）Switch as closed mode.
When fluidized bed granulation starts, the first fluidic interface 1 is opened（Connect 50 degrees Celsius of gelatin solution）The first valve 7
Switch, gelatin solution enters in fluid path 4, while compressed air enters gas passage 5 by gas interface, in certain spray
Under hydraulic coupling, binder solution（Gelatin solution）Spray pattern is formed, is sprayed on the material in fluid bed product chambers, is constantly formed
Particle.
After fluidized bed granulation terminates, by the first fluidic interface 1（Connect 50 degrees Celsius of gelatin solution）The valve of interface first
The switch of door 7 is closed, and opens second liquid interface 2（Hot water）The second valve 8 switch, rinse spray gun pipeline（Fluid path 4）, keep away
Exempt from nozzle 6 to block.
This method is simple and easy to do, hence it is evident that improves cleaning and operating efficiency.
Embodiment two：The application method of the utility model fluid bed liquid-jet device
Fluidized bed granulation uses adhesive HPC simultaneously（Hydroxypropyl cellulose）Solution and protective agent PEG（Polyethylene glycol）It is molten
Liquid.
Before fluidized bed granulation, the first fluidic interface 1 is connect into HPC solution, second liquid interface 2 is connect into PEG solution, gas
Interface 3 is connected in compressed air.The valve of HPC solution and PEG solution（First valve 7 and the second valve 8）Switch to close shape
State.
When fluidized bed granulation starts, the valve of the first fluidic interface 1 and second liquid interface 2 is opened（First valve 7 and
Two valves 8）Switch, HPC solution and PEG solution enter in fluid path 4 simultaneously, while compressed air is entered by gas interface 3
Enter gas passage 5, under certain hydrojet pressure, HPC solution and PEG solution form spray pattern, are sprayed on fluid bed product chambers
On interior material, particle is constantly formed.
HPC and PEG is water miscible material, can be competing the HPC of high concentration and PEG is dissolved in the aqueous solution simultaneously when
The water striven in solution and separate out one of which.In the present embodiment, HPC and PEG is distinguished into wiring solution-forming, by the liquid of spray gun
The time of body path 4 is very short, can realize that the merging of two kinds of solution uses.
Claims (8)
- A kind of 1. bed spray device, it is characterised in that including two fluidic interfaces and a gas interface, fluid path, Gas passage and nozzle；Described two fluidic interfaces are connected with the fluid path, one gas interface and the gas Path is connected, and the fluid path intersects with the gas passage end and is connected with the nozzle.
- 2. bed spray device according to claim 1, it is characterised in that be respectively equipped with described two fluidic interfaces One valve.
- 3. bed spray device according to claim 1, it is characterised in that described two fluidic interfaces are pooled to liquid In path and nozzle is connected, the gas interface is passed through in gas passage and liquid is formed spray pattern at nozzle.
- 4. bed spray device according to claim 1, it is characterised in that the angle between described two fluidic interfaces For 30 ° -90 °；Angle between the gas interface and the either interface of described two fluidic interfaces is identical, is 30 ° -90 °； Angle between the gas interface and the gas passage is more than 90 degree.
- 5. bed spray device according to claim 1, it is characterised in that described two fluidic interfaces and the liquid Path is generally aligned in the same plane；The fluid path is located inside the gas passage；The liquid inlet of described two fluidic interfaces Positioned at the outside of the gas passage.
- 6. bed spray device according to claim 1, it is characterised in that the diameter phase of described two fluidic interfaces Together；The diameter of described two fluidic interfaces is less than the diameter of the gas interface.
- 7. bed spray device according to claim 6, it is characterised in that the diameter of the gas interface is at least institute State fluidic interface diameter 2 times, the diameter range of the fluidic interface are 3.0mm-5.0mm, the diameter model of the gas interface Enclose for 6.0mm-10.0mm.
- 8. bed spray device according to claim 1, it is characterised in that described two fluidic interfaces connect difference respectively Liquid；The gas interface connects compressed air.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721343305.8U CN207138143U (en) | 2017-10-18 | 2017-10-18 | A kind of bed spray device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201721343305.8U CN207138143U (en) | 2017-10-18 | 2017-10-18 | A kind of bed spray device |
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| Publication Number | Publication Date |
|---|---|
| CN207138143U true CN207138143U (en) | 2018-03-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201721343305.8U Active CN207138143U (en) | 2017-10-18 | 2017-10-18 | A kind of bed spray device |
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| CN (1) | CN207138143U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107649302A (en) * | 2017-10-18 | 2018-02-02 | 上海合全医药有限公司 | A kind of bed spray device and its application method |
-
2017
- 2017-10-18 CN CN201721343305.8U patent/CN207138143U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107649302A (en) * | 2017-10-18 | 2018-02-02 | 上海合全医药有限公司 | A kind of bed spray device and its application method |
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 200131 Pudong New Area, Shanghai, China (Shanghai) free trade pilot area, 211 North 302, 368 room. Co-patentee after: Wuxi Hequan Pharmaceutical Co., Ltd. Patentee after: Shanghai complete Pharmaceutical Co., Ltd. Address before: 200131 Pudong New Area, Shanghai, China (Shanghai) free trade pilot area, 211 North 302, 368 room. Co-patentee before: Wuxi Wuxi Pharmaceutical Co. Ltd. Patentee before: Shanghai complete Pharmaceutical Co., Ltd. |
|
| CP01 | Change in the name or title of a patent holder |