CN207108997U - Fungal infection automatic tester - Google Patents

Fungal infection automatic tester Download PDF

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Publication number
CN207108997U
CN207108997U CN201720966865.2U CN201720966865U CN207108997U CN 207108997 U CN207108997 U CN 207108997U CN 201720966865 U CN201720966865 U CN 201720966865U CN 207108997 U CN207108997 U CN 207108997U
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China
Prior art keywords
base
rotating disk
sampling
unit
incubated
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Active
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CN201720966865.2U
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Chinese (zh)
Inventor
宫平
马辰昊
王越
于源华
王哲
孟祥凯
刘传志
朱海焕
杨羽
侯玥
杨卓
谭国桢
李琦
刘丹
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SHANGHAI YUANQI BIOMEDICAL TECHNOLOGY CO.,LTD.
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Changchun University of Science and Technology
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Priority to CN201720966865.2U priority Critical patent/CN207108997U/en
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Abstract

Fungal infection automatic tester belongs to Automatic Measurement Technique field, it is therefore intended that solves the problems, such as cumbersome, complicated existing for prior art and increase medical worker's workload.The utility model includes testing sample load units;Rotate sampling unit;Shake unit;Detection unit is incubated, being incubated detection unit includes being incubated base, the couveuse rotating disk being incubated on base is connected to by hatch unit power drive mechanism, below the couveuse rotating disk and being fixed on and be incubated the heating dish of base upper surface, be arranged on the outside of heating dish and couveuse rotating disk and lower end and be fixed on the tubular stay-warm case being incubated on base and the luminous and detection unit being arranged on the outside of heating dish;The gripper being fixedly connected with the elevating lever upper end of rotation sampling unit;Accommodate the reaction utensil of detected sample;And computer control, the computer control control testing sample load units, rotation sampling unit, concussion unit, incubation detection unit action.

Description

Fungal infection automatic tester
Technical field
The utility model belongs to Automatic Measurement Technique field, and in particular to fungal infection automatic tester.
Background technology
1,3- calloses present in deep fungal cell membrane, it is the distinctive composition of deep fungal, by using inspection The 1,3- calloses content surveyed in blood, urine, pleural effusion, ascites equal samples can determine that patient is fungi-infected The order of severity.
ELISA is used, belongs to wet using enzyme micro-plate reader detection fungal infection, enzyme micro-plate reader in the prior art Biochemistry, detection carrier is 96 orifice plates, cumbersome, complicated using enzyme micro-plate reader detection method, increases medical worker's workload, It can not be not suitable for basic hospital with to inspection and medical and health organization use.
Utility model content
The purpose of this utility model is to propose fungal infection automatic tester that it is numerous to solve the existing operation of prior art The problem of trivial, complicated and increase medical worker's workload.
To achieve the above object, fungal infection automatic tester of the present utility model includes:
Testing sample load units, the testing sample load units include loading base and pass through load units power Transmission mechanism is connected to the first rotating disk loaded on base, drives the first rotating disk to turn by load units power drive mechanism Move and move along the x-axis, the multiple containing tanks of circumference uniform distribution in first rotating disk;
Sampling unit is rotated, the rotation sampling unit includes sampling base and passes through sampling unit power drive mechanism The elevating lever being connected on sampling base, elevating lever is driven to turn about the Z axis and along Z axis by sampling unit power drive mechanism Lower motion;
Unit is shaken, the concussion unit includes concussion base and is connected to shake by shaking unit power drive mechanism The second rotating disk on base is swung, drives the second rotating disk to turn about the Z axis and shake, institute by shaking unit power drive mechanism State the multiple containing tanks of circumference uniform distribution in the second rotating disk;
Detection unit is incubated, the incubation detection unit includes being incubated base, connected by hatch unit power drive mechanism Be connected on be incubated on base couveuse rotating disk, below the couveuse rotating disk and be fixed on be incubated base upper surface heating dish, It is arranged on the outside of heating dish and couveuse rotating disk and lower end is fixed on the tubular stay-warm case being incubated on base and is arranged on and adds The luminous and detection unit of hot plate outer ring surface;Couveuse rotating disk is driven to turn about the Z axis by hatch unit power drive mechanism, institute State couveuse rotating disk and be distributed more loop diameter identical through holes, outermost is as detecting position, and inner side is as incubation position;The heating dish Multi-ring annular groove is provided with the through hole correspondence position of the couveuse rotating disk, temperature sensor is provided with the heating dish;
The gripper being fixedly connected with the elevating lever upper end, testing sample load units, concussion unit and incubation detection Unit is located at the lower section of gripper swinging track;
For accommodating the reaction utensil of detected sample, the reaction utensil can be placed on the first rotating disk, the second rotating disk On couveuse rotating disk;
And computer control, the computer control control testing sample load units, rotation sampling unit, shake Swing unit, be incubated detection unit action.
The reaction utensil includes the first liquid pipe, the second liquid pipe, boost tube and the host pipe from top to bottom set gradually;It is described First liquid pipe and the second liquid pipe lower end are sealed by masking foil;Lower end is ring structure on the outside of first liquid pipe, insertion There is prong structure second liquid pipe interior sealing, the second liquid pipe upper end, can pierce the first liquid pipe lower end residue masking foil, and prong structure has Through hole, the second liquid pipe lower end can be flowed liquid into;Lower end is ring structure on the outside of second liquid pipe, inserts boost tube interior sealing; There is prong structure boost tube upper end, can pierce the second liquid pipe lower end masking foil, and prong structure has through hole, and UNICOM's boost tube lower end adds Sample pin, liquid can be made to flow into host pipe by sample needle;Lower end is ring structure on the outside of boost tube, is inserted close in host pipe Envelope;Host pipe is colorimetric cup structure.
The load units power drive mechanism includes:
The guide rail loaded on base is fixed on along X-direction;
The sliding block being slidably matched with the guide rail;
The leading screw set with the guide rail parallel;
The nut being fixedly connected with the sliding block;The nut and the leading screw form screw pair;
The first motor connected with described leading screw one end;
It is fixed on the slide unit of upper end of slide block;
And the second motor of slide unit upper end is fixed on, the rotating shaft of second motor and first rotating disk, which is fixed, to be connected Connect.
The sampling unit power drive mechanism includes:
The up-down mechanism being arranged on sampling base, the elevating lever pass through sampling base upper plate and the fortune up and down Motivation structure connects, and drives elevating lever to rise or fall by up-down mechanism;
And the rotational motion mechanism on sampling base is arranged on, the rotational motion mechanism drives elevating lever to turn about the z axis It is dynamic.
The up-down mechanism includes:
The 3rd motor being fixed in sampling base lower plate;
The first driving pulley connected with the 3rd motor output shaft;
The first driven pulley with first driving pulley by the first synchronous band connection;
And the timing belt clamping plate fixed with the timing belt by screw, the timing belt clamping plate pass through bearing and described Elevating lever lower end connects, and drives elevating lever to move up and down by the reciprocating motion of timing belt;
The rotational motion mechanism includes:
It is fixed on the 4th motor of the upper plate lower surface of the sampling base;
The second driving pulley connected with the 4th motor output shaft;
The second driven pulley with second driving pulley by the second synchronous band connection, second driven pulley exist The upper plate rotation of base is sampled, and it is coaxial with elevating lever;
With flap under the guide rod of the sampling base lower plate rotatable engagement;
The guide rod that both ends connect with flap under the second driven pulley and guide rod respectively;
And the lifting supporting plate on the guide rod is enclosed on, the lifting supporting plate is fixedly connected with the elevating lever lower end.
The gripper includes:
The sampling arm that one end is fixedly connected with the elevating lever upper end, the sampling arm middle part are provided with strain transducer;
The gripper shell connected with the sampling arm other end;
And crawl structure, the crawl structure are that have one end to be located in gripper shell respectively two are arranged in a crossed manner Z-shaped pawl, two Z-shaped pawl upper ends are connected by spring, and lower end relative position is provided with PVDF membrane sensor, and two Individual Z-shaped pawl infall rotates axis connection, the Z-shaped pawl rotary shaft and the gripper cage connection by Z-shaped pawl, and two Z-shaped Electromagnet is housed, magnet spool disconnects and turned on the folding for realizing two Z-shaped pawls among pawl upper arm.
The concussion unit power drive mechanism includes:
The 5th motor on fixed earthquake base;
The eccentric shaft that one end is fixedly connected with the 5th motor output shaft;
The second shake table connected with the eccentric shaft other end, it is straight more than eccentric shaft that the second shake table center is provided with diameter The through hole in footpath, eccentric shaft upper end are inserted into the through hole of the second shake table;
The shake table of frame shape first being arranged on the outside of the second shake table, two relative side walls of first shake table it is interior Side is connected by a vibrating reed respectively with side wall corresponding to second shake table, described two other side wall of first shake table One end respectively with a vibrating reed of outside connect, the other end of two vibrating reeds passes through a support and vibrations base respectively Connect, two vibrating reeds on the outside of the first shake table are equal and two vibrating reeds of inner side are vertical;
And the 6th motor on the first shake table is fixed on, the 6th motor output shaft and the connection of the second rotating disk.
The hatch unit power drive mechanism includes:
It is fixed on the 7th motor being incubated on base;
And the rotating shaft connected by gear drive with the 7th motor output shaft, the rotating shaft, which passes through, is incubated base simultaneously Connected with base is incubated by bearing, the rotating shaft upper end is fixedly connected with the couveuse rotating disk.
The luminous and detection unit includes 405nmLED, 490nmLED, 405nm narrow band pass filter, 490nm narrow-band-filters Piece, feed back receiver, spectroscope and photodetector;405nmLED emits beam after 405nm narrow band pass filters, a part Light is received by a feed back receiver on the outside of optical axis, and detection bypass light intensity, another part chief ray passes through spectroscope Reaction utensil is passed through after transmission, is received by a photoelectric detector, 490nmLED emits beam after 490nm narrow band pass filters, one Light splitter is received by another feed back receiver on the outside of optical axis, and detection bypass light intensity, another part chief ray is by light splitting Reaction utensil is passed through after mirror reflection, is received by a photoelectric detector, two-way light passes through spectroscope common optical axis.
The automatic tester also includes pedestal and waste material box, the loading base, sampling base, concussion base, incubation Base and waste material box are fixed on the pedestal, and the gripper oscillating motion process is by above the waste material box.
The beneficial effects of the utility model are:The host of reaction utensil in fungal infection automatic tester of the present utility model Pipe, boosting wound packages are with firm, and the second liquid pipe is assembled on boosting cylinder, outer side position, and operator utilizes sample injector thorn during operation Testing liquid is added the first liquid pipe, vertical first liquid pipe by the masking foil for wearing the first liquid pipe, and the first liquid pipe is inserted into the second liquid In pipe, 180 ° are rotated, mix reagent is flowed into the second liquid pipe, and concussion blending incubation presses the first liquid pipe, boosting cylinder after 10 minutes Prong can pierce the second liquid pipe lower end masking foil, and mix reagent is injected into host pipe using boosting cylinder sample needle, with host pipe Middle reaction reagent B mixing, reacts 30 minutes, for measuring change in optical signal, the structure design of reaction utensil can be very good to make to treat Test sample product mix with reaction reagent A and reaction reagent B successively.
The utility model captures entirely through computer control system control action, manipulator from testing sample load units Reaction utensil is placed into the second rotating disk of concussion unit, concussion unit concussion 10s, reaction is done reagent A and is filled with testing sample Divide and mix, rotation sampling arm captures reaction utensil, places it in the incubation area for the couveuse rotating disk for being incubated detection unit, incubation 10 Minute, rotation sampling arm crawl reaction utensil, it is placed into the second rotating disk of concussion unit, and carry out pressing operation by the Inside two liquid pipes insertion boosting cylinder, pierce through masking foil and be injected into mix reagent in host pipe using boosting cylinder sample needle, with master Reagent B is mixed in agent pipe, and concussion 10s makes it fully mix, and it is single that rotation sampling arm crawl reaction utensil places it in incubation detection The detection zone of the couveuse rotating disk of member is detected, and the second rotating disk rotates, and per 30s, rotation is turned around, and reaction utensil passes through one per 30s Secondary Photoelectric Detection area, a signal detection is carried out, persistently detects 30min.Testing result is exported after data processing, and rotates and takes Reaction utensil is disposal to waste material box by sample arm crawl reaction utensil.Couveuse detection unit when being incubated and detecting work, other Unit can be normally carried out work, and operating efficiency is high;Integrated operation is controlled by computer control system and completed, simple to operate, Reduce medical worker's workload.
Brief description of the drawings
Fig. 1 is fungal infection automatic tester overall structure diagram of the present utility model;
Fig. 2 is reaction utensil structural front view in fungal infection automatic tester of the present utility model;
Fig. 3 is reaction utensil structure left view in fungal infection automatic tester of the present utility model;
Fig. 4 is Fig. 3 A-A sectional views;
Fig. 5 is the section view explosive view of reaction utensil in fungal infection automatic tester of the present utility model;
Fig. 6 is testing sample load units structural representation in fungal infection automatic tester of the present utility model;
Fig. 7 is testing sample load units front view in fungal infection automatic tester of the present utility model;
Fig. 8 is testing sample load units left view in fungal infection automatic tester of the present utility model;
Fig. 9 is testing sample load units top view in fungal infection automatic tester of the present utility model;
Figure 10 is that sampling unit structural representation is rotated in fungal infection automatic tester of the present utility model;
Figure 11 is that sampling unit structure left view is rotated in fungal infection automatic tester of the present utility model;
Figure 12 is gripper structural representation in fungal infection automatic tester of the present utility model;
Figure 13 is to shake cellular construction schematic diagram in fungal infection automatic tester of the present utility model;
Figure 14 is that cellular construction left view is shaken in fungal infection automatic tester of the present utility model;
Figure 15 is that detection unit structural representation is incubated in fungal infection automatic tester of the present utility model;
Figure 16 is that detection unit structural front view is incubated in fungal infection automatic tester of the present utility model;
Figure 17 is luminous and detection unit index path in fungal infection automatic tester of the present utility model;
Wherein:1st, testing sample load units, 101, load base, the 102, first rotating disk, 103, guide rail, 104, sliding Block, 105, slide unit, 106, leading screw, 107, nut, the 108, first motor, the 109, second motor, 2, rotation sampling unit, 201, take Sample base, 202, elevating lever, the 203, the 3rd motor, the 204, first driving pulley, the 205, first timing belt, the 206, first driven belt Wheel, 207, timing belt clamping plate, the 208, the 4th motor, the 209, second driving pulley, the 210, second timing belt, the 211, second driven belt Wheel, 212, guide rod, 213, flap under guide rod, 214, lifting supporting plate, 215, upper fixed cover, 216, lower fixed cover, 3, machinery Pawl, 301, sampling arm, 302, gripper shell, 303, Z-shaped pawl, 304, spring, 305, PVDF membrane sensor, 306, Z-shaped pawl rotary shaft, 307, electromagnet, 4, concussion unit, 401, concussion base, the 402, second rotating disk, the 403, the 5th motor, 404th, eccentric shaft, the 405, first shake table, the 406, second shake table, 407, vibrating reed, the 408, the 6th motor, 5, to be incubated detection single Member, 501, be incubated base, 502, couveuse rotating disk, 503, stay-warm case, the 504, the 7th motor, 505, gear drive, 506, rotating shaft, 507th, 405nmLED, 508,490nmLED, 509,405nm narrow band pass filters, 510,490nm narrow band pass filters, 511, feedback connects Receive device, 512, spectroscope, 513, photodetector, 6, reaction utensil, the 601, first liquid pipe, the 602, second liquid pipe, 603, boost tube, 604th, host pipe, 7, computer control, 8, waste material box, 9, pedestal.
Embodiment
Embodiment of the present utility model is described further below in conjunction with the accompanying drawings.
Referring to accompanying drawing 1, fungal infection automatic tester of the present utility model includes:
Testing sample load units 1, the testing sample load units 1 include loading base 101 and by loading list First power drive mechanism is connected to the first rotating disk 102 loaded on base 101, is driven by load units power drive mechanism First rotating disk 102 is rotated and moved along the x-axis, the multiple containing tanks of circumference uniform distribution in first rotating disk 102;
Sampling unit 2 is rotated, the rotation sampling unit 2 includes sampling base 201 and passed by sampling unit power Motivation structure is connected to the elevating lever 202 on sampling base 201, and elevating lever 202 is driven around Z by sampling unit power drive mechanism Axle is rotated and moved up and down along Z axis;
Unit 4 is shaken, the concussion unit 4 includes concussion base 401 and connected by shaking the power drive mechanism of unit 4 Be connected on concussion base 401 on the second rotating disk 402, by shake the power drive mechanism of unit 4 drive the second rotating disk 402 around Z axis rotates and vibrations, the multiple containing tanks of circumference uniform distribution in second rotating disk 402;
Detection unit 5 is incubated, the incubation detection unit 5 includes being incubated base 501, passes through hatch unit power transmission machine Structure is connected to the couveuse rotating disk 502 being incubated on base 501, positioned at the lower section of couveuse rotating disk 502 and is fixed on and is incubated base 501 The heating dish of upper surface, it is arranged on heating dish and the outside of couveuse rotating disk 502 and lower end is fixed on the cylinder being incubated on base 501 Shape stay-warm case 503 and the luminous and detection unit for being arranged on heating dish outer ring surface;Pass through hatch unit power drive mechanism band Dynamic couveuse rotating disk 502 turns about the Z axis, and the couveuse rotating disk 502 is distributed more loop diameter identical through holes, and outermost is as inspection Location, inner side is as incubation position;The through hole correspondence position of the heating dish and the couveuse rotating disk 502 is provided with multi-ring annular Groove, temperature sensor and resistive heater are provided with the heating dish;
The gripper 3 being fixedly connected with the upper end of elevating lever 202, testing sample load units 1, shake unit 4 and incubate Educate the lower section that detection unit 5 is located at the swinging track of gripper 3;
For accommodating the reaction utensil 6 of detected sample, the reaction utensil 6 can be placed on the rotation of the first rotating disk 102, second On rotating disk 402 and couveuse rotating disk 502;
And computer control 7, the computer control 7 control testing sample load units 1, rotation sampling unit 2nd, unit 4 is shaken, incubation detection unit 5 acts.
Referring to accompanying drawing 2-5, the reaction utensil 6 include from top to bottom set gradually the first liquid pipe 601, the second liquid pipe 602, Boost tube 603 and host pipe 604;First liquid pipe 601 and the lower end of the second liquid pipe 602 are sealed by masking foil;The The outside lower end of one liquid pipe 601 is ring structure, inserts the interior sealing of the second liquid pipe 602, there is prong knot the upper end of the second liquid pipe 602 Structure, can pierce the lower end residue masking foil of the first liquid pipe 601, and prong structure has through hole, can flowed liquid under the second liquid pipe 602 End;The outside lower end of second liquid pipe 602 is ring structure, inserts the interior sealing of boost tube 603;There is prong knot the upper end of boost tube 603 Structure, can pierce the lower end masking foil of the second liquid pipe 602, and prong structure has through hole, the lower end sample needle of UNICOM's boost tube 603, can make liquid Body flows into host pipe 604 by sample needle;The outside lower end of boost tube 603 is ring structure, the interior sealing of insertion host pipe 604; Host pipe 604 is colorimetric cup structure.
Reaction reagent A is placed with first liquid pipe 601, host pipe 604 is built with reaction reagent B, reaction reagent A and sample 37 DEG C of this mixing mixes with reaction reagent B again after being incubated 10 minutes, if containing 1 in sample, 3- calloses, mixed solution will The specific agglutinating reaction of generation, 1,3- callose contents can be measured using photodetector 513, and then know fungi Gradient of infection.
Referring to accompanying drawing 6-9, the load units power drive mechanism includes:
The guide rail 103 loaded on base 101 is fixed on along X-direction;
The sliding block 104 being slidably matched with the guide rail 103;
The leading screw 106 being be arranged in parallel with the guide rail 103;
The nut 107 being fixedly connected with the sliding block 104;The nut 107 and the leading screw 106 form the spiral shell of leading screw 106 Mother 107 is secondary;
The first motor 108 connected with described one end of leading screw 106;
It is fixed on the slide unit 105 of the upper end of sliding block 104;
And it is fixed on the second motor 109 of the upper end of slide unit 105, second motor 109 and first rotating disk 102 Rotating shaft is fixedly connected.
Referring to accompanying drawing 10-11, the sampling unit power drive mechanism includes:
Be arranged on sampling base 201 on up-down mechanism, the elevating lever 202 through sampling the upper plate of base 201 and The up-down mechanism connection, drives elevating lever 202 to rise or fall by up-down mechanism;
And be arranged on the rotational motion mechanism on sampling base 201, the rotational motion mechanism drive elevating lever 202 around Z axis rotates.
The up-down mechanism includes:
The 3rd motor 203 being fixed in the sampling lower plate of base 201;
With the first driving pulley 204 of the 3rd motor 203 output axis connection;
The first driven pulley 206 connected with first driving pulley 204 by the first timing belt 205;
And the timing belt clamping plate 207 fixed with the timing belt by screw, the timing belt clamping plate 207 pass through bearing Connected with the lower end of elevating lever 202, drive elevating lever 202 to move up and down by the reciprocating motion of timing belt.
The rotational motion mechanism includes:
It is fixed on the 4th motor 208 of the upper plate lower surface of the sampling base 201;
With the second driving pulley 209 of the 4th motor 208 output axis connection;
The second driven pulley 211 connected with second driving pulley 209 by the second timing belt 210, described second Driven pulley 211 is connected on sampling base 201 by upper fixed cover 215 and lower fixed cover 216, and relative sampling base 201 Upper plate rotation, and coaxial with elevating lever 202, upper fixed cover 215 and lower fixed cover 216 are connected by screw;
With flap 213 under the guide rod of the sampling lower plate rotatable engagement of base 201;
The guide rod 212 that both ends connect with flap 213 under the second driven pulley 211 and guide rod respectively;
And the lifting supporting plate 214 on the guide rod 212 is enclosed on, under the lifting supporting plate 214 and the elevating lever 202 End is fixedly connected.
Referring to accompanying drawing 12, the gripper 3 includes:
The sampling arm 301 that one end is fixedly connected with the upper end of elevating lever 202, the middle part of sampling arm 301 is provided with should Become sensor, the measurable vertical direction stress of sampling arm 301;
The gripper shell 302 connected with the other end of sampling arm 301;
And crawl structure, the crawl structure are that two intersections for having one end to be located in gripper shell 302 respectively are set The Z-shaped pawl 303 put, two Z-shaped upper ends of pawl 303 are connected by spring 304, and lower end relative position is provided with poly- inclined difluoro second Alkene film sensors 305, the measurable grasp force of gripper 3, to judge whether to catch reaction utensil 6, two Z-shaped infalls of pawl 303 lead to Cross Z-shaped pawl rotary shaft 306 to connect, the Z-shaped pawl rotary shaft 306 and the gripper shell 302 connect, on two Z-shaped pawls 303 Electromagnet 307 is housed, the coil of electromagnet 307 disconnects and turned on the folding for realizing two Z-shaped pawls 303 among arm.
Referring to accompanying drawing 13-14, the concussion unit power drive mechanism includes:
The 5th motor 403 on fixed earthquake base 401;
The eccentric shaft 404 that one end is fixedly connected with the output shaft of the 5th motor 403;
The second shake table 406 connected with the other end of eccentric shaft 404, the center of the second shake table 406 are provided with diameter summary More than the through hole of the diameter of eccentric shaft 404, the upper end of eccentric shaft 404 is inserted into the through hole of the second shake table 406;
Be arranged on first shake table of frame shape 405 in the outside of the second shake table 406, first shake table 405 it is relative two Side wall corresponding to the inner side of individual side wall and second shake table 406 is connected by a vibrating reed 407 respectively, and described first shakes The one end of the outside of two other side wall of dynamic platform 405 respectively with a vibrating reed 407 connects, the other end of two vibrating reeds 407 Connect respectively by a support with vibrations base, two vibrating reeds 407 in the outside of the first shake table 405 are equal and two of inner side Vibrating reed 407 is vertical;
And the 6th motor 408 on the first shake table 405 is fixed on, the output shaft of the 6th motor 408 and the second rotation Rotating disk 402 connects.
Referring to accompanying drawing 15-16, the hatch unit power drive mechanism includes:
It is fixed on the 7th motor 504 being incubated on base 501;
And the rotating shaft 506 of axis connection is exported by gear drive 505 and the 7th motor 504, the rotating shaft 506 is worn Cross incubation base 501 and connected with base 501 is incubated by bearing, the upper end of rotating shaft 506 and the couveuse rotating disk 502 are solid Fixed connection.
Referring to accompanying drawing 17, the luminous and detection unit is filtered including 405nmLED507,490nmLED508,405nm arrowband Mating plate 509,490nm narrow band pass filters 510, feed back receiver 511, spectroscope 512 and photodetector 513;405nmLED507 Emit beam after 405nm narrow band pass filters 509, a part of light is by a feed back receiver 511 on the outside of optical axis Receive, detection bypass light intensity, another part chief ray passes through reaction utensil 6 after the transmission of spectroscope 512, by photodetector 513 receive, and 490nmLED508 emits beam after 490nm narrow band pass filters 510, and a part of light is by the outside of optical axis Another feed back receiver 511 receive, detection bypass light intensity, another part chief ray is after the reflection of spectroscope 512 through anti- Ware 6 is answered, is received by photodetector 513, two-way light passes through the common optical axis of spectroscope 512.
The automatic tester also includes pedestal 9 and waste material box 8, the loading base 101, sampling base 201, concussion bottom Seat 401, incubation base 501 and waste material box 8 are fixed on the pedestal 9, and the oscillating motion process of gripper 3 is by described useless The top of magazine 8.
First rotating disk 102 is identical with the structure of the second rotating disk 402, and including upper and lower two layers, upper strata rotating disk is set Through hole is equipped with, lower floor's rotating disk correspondence position is provided with counterbore, and the lower end of reaction utensil 6 is located in the counterbore of lower floor's rotating disk, upper end Stretched out from upper strata rotating disk, the through hole is above-mentioned containing tank.
The utility model is specially by the control action of computer control 7:The computer control 7 and strain sensing Device, PVDF membrane sensor 305, temperature sensor, feed back receiver 511, photodetector 513, the first motor 108th, the second motor 109, the 3rd motor 203, the 4th motor 208, the 5th motor 403, the 6th motor 408, the 7th motor 504, Electromagnet 307, resistive heater, 405nmLED507,490nmLED508 electrical connection.For detecting strain transducer, poly- inclined two Fluoride film sensor 305, temperature sensor, feed back receiver 511, the signal of photodetector 513, control the first motor 108th, the second motor 109, the 3rd motor 203, the 4th motor 208, the 5th motor 403, the 6th motor 408, the 7th motor 504 revolve Turn, control electromagnet 307, resistive heater, 405nmLED507,490nmLED508 switch, the computer control 7 can be right Each sensor signal processing, obtains fungal infection degree.
The detailed process detected using the utility model is included with lower part:
Reaction utensil 6 is put into before testing sample load units 1, and the tinfoil paper of the first liquid pipe 601 is manually pierced through by sample injector Testing liquid is added the first liquid pipe 601 by paper, and the first liquid pipe 601 is inserted equipped with the dry reagent A of reaction in the inside of the first liquid pipe 601 In second liquid pipe 602, in the first rotating disk 102 of the testing sample load units 1 that reaction utensil 6 is placed on to detecting instrument, open Begin to test.
It is automatically brought into operation part:The first rotating disk of instrument controlling 102 moves to instrument internal, moves to product to be tested crawl position, Rotation sampling arm 301 goes to product to be tested crawl position and the crawl of reaction utensil 6 is placed into the second rotating disk 402 of concussion unit 4, this When instrument can continue load sample.
Shake unit 4 and shake 10s, reaction is done reagent A and fully mixed with testing sample, rotation sampling arm 301 captures instead Ware 6 is answered, places it in the incubation area for the couveuse rotating disk 502 for being incubated detection unit 5, is incubated 10 minutes, during which instrument can be after It is continuous to load sample.
Sampling arm 301 is rotated after being incubated 10 minutes and captures reaction utensil 6, is placed into the second rotating disk of concussion unit 4 On 402, and carry out pressing operation and insert the second liquid pipe 602 inside boosting cylinder, pierce through masking foil and mix reagent is utilized into boosting The sample needle of pipe 603 is injected into host pipe 604, is mixed with reagent B in host pipe 604, and concussion 10s makes it fully mix.
Rotation sampling arm 301 captures the detection that reaction utensil 6 places it in the couveuse rotating disk 502 for being incubated detection unit 5 Area is detected, and the second rotating disk 402 rotates, and per 30s, rotation is turned around, and reaction utensil 6 passes through a Photoelectric Detection area per 30s, enters Signal detection of row, persistently detects 30min.
Testing result is exported after data processing, and rotate sampling arm 301 capture reaction utensil 6 reaction utensil 6 is disposal to it is useless Magazine 8.

Claims (10)

1. fungal infection automatic tester, it is characterised in that including:
Testing sample load units (1), the testing sample load units (1) include loading base (101) and pass through loading Unit power drive mechanism is connected to the first rotating disk (102) loaded on base (101), passes through load units power transmission machine Structure drives the first rotating disk (102) to rotate and move along the x-axis, the multiple containing tanks of circumference uniform distribution on first rotating disk (102);
Sampling unit (2) is rotated, the rotation sampling unit (2) includes sampling base (201) and passes through sampling unit power Transmission mechanism is connected to the elevating lever (202) on sampling base (201), and elevating lever is driven by sampling unit power drive mechanism (202) turn about the Z axis and moved up and down along Z axis;
Unit (4) is shaken, the concussion unit (4) includes concussion base (401) and by shaking unit (4) power transmission machine The second rotating disk (402) on structure connection earthquake base (401), second is driven by shaking unit (4) power drive mechanism Rotating disk (402) is turned about the Z axis and shaken, the multiple containing tanks of circumference uniform distribution on second rotating disk (402);
Detection unit (5) is incubated, the incubation detection unit (5) includes being incubated base (501), passes through hatch unit power transmission Mechanism is connected to the couveuse rotating disk (502) being incubated on base (501), below couveuse rotating disk (502) and is fixed on and incubates Educate the heating dish of base (501) upper surface, be arranged on heating dish and couveuse rotating disk (502) on the outside of and lower end be fixed on incubation Tubular stay-warm case (503) on base (501) and the luminous and detection unit for being arranged on heating dish outer ring surface;It is single by being incubated First power drive mechanism drives couveuse rotating disk (502) to turn about the Z axis, and the couveuse rotating disk (502) is distributed more loop diameter phases Same through hole, outermost is as detecting position, and inner side is as incubation position;The heating dish and the couveuse rotating disk (502) it is logical Hole correspondence position is provided with multi-ring annular groove, and temperature sensor is provided with the heating dish;
The gripper (3) being fixedly connected with the elevating lever (202) upper end, testing sample load units (1), concussion unit (4) It is located at the lower section of gripper (3) swinging track with incubation detection unit (5);
For accommodating the reaction utensil (6) of detected sample, the reaction utensil (6) can be placed on the first rotating disk (102), second In rotating disk (402) and couveuse rotating disk (502);
And computer control (7), computer control (7) the control testing sample load units (1), rotation sampling are single First (2), concussion unit (4), it is incubated detection unit (5) action.
2. fungal infection automatic tester according to claim 1, it is characterised in that the reaction utensil (6) is included by upper The first liquid pipe (601), the second liquid pipe (602), boost tube (603) and the host pipe (604) set gradually under;First liquid Pipe (601) and second liquid pipe (602) lower end is sealed by masking foil;Lower end is sealing ring on the outside of first liquid pipe (601) Structure, the second liquid pipe (602) interior sealing is inserted, there is prong structure the second liquid pipe (602) upper end, can pierce the first liquid pipe (601) Lower end residue masking foil, prong structure have through hole, can flow liquid into the second liquid pipe (602) lower end;On the outside of second liquid pipe (602) Lower end is ring structure, inserts boost tube (603) interior sealing;There is prong structure boost tube (603) upper end, can pierce the second liquid (602) lower end masking foil is managed, prong structure has through hole, UNICOM's boost tube (603) lower end sample needle, liquid can be made to pass through sample needle Flow into host pipe (604);Lower end is ring structure on the outside of boost tube (603), inserts host pipe (604) interior sealing;Host pipe (604) it is colorimetric cup structure.
3. fungal infection automatic tester according to claim 1, it is characterised in that the load units power transmission machine Structure includes:
The guide rail (103) loaded on base (101) is fixed on along X-direction;
The sliding block (104) being slidably matched with the guide rail (103);
The leading screw (106) being be arranged in parallel with the guide rail (103);
The nut (107) being fixedly connected with the sliding block (104);The nut (107) and the leading screw (106) form leading screw (106) nut (107) is secondary;
The first motor (108) connected with the leading screw (106) one end;
It is fixed on the slide unit (105) of sliding block (104) upper end;
And second motor (109) of slide unit (105) upper end is fixed on, second motor (109) and first rotating disk (102) rotating shaft is fixedly connected.
4. fungal infection automatic tester according to claim 1, it is characterised in that the sampling unit power transmission machine Structure includes:
The up-down mechanism being arranged on sampling base (201), the elevating lever (202) pass through sampling base (201) upper plate Connected with the up-down mechanism, drive elevating lever (202) to rise or fall by up-down mechanism;
And be arranged on the rotational motion mechanism in sampling base (201), the rotational motion mechanism drive elevating lever (202) around Z axis rotates.
5. fungal infection automatic tester according to claim 4, it is characterised in that the up-down mechanism includes:
The 3rd motor (203) being fixed in sampling base (201) lower plate;
With the first driving pulley (204) of the 3rd motor (203) output axis connection;
The first driven pulley (206) connected with first driving pulley (204) by the first timing belt (205);
And the timing belt clamping plate (207) fixed with the timing belt by screw, the timing belt clamping plate (207) pass through bearing Connected with the elevating lever (202) lower end, drive elevating lever (202) to move up and down by the reciprocating motion of timing belt;
The rotational motion mechanism includes:
It is fixed on the 4th motor (208) of the upper plate lower surface of the sampling base (201);
With the second driving pulley (209) of the 4th motor (208) output axis connection;
The second driven pulley (211) connected with second driving pulley (209) by the second timing belt (210), described Two driven pulleys (211) rotate in the upper plate of sampling base (201), and coaxial with elevating lever (202);
With flap (213) under the guide rod of described sampling base (201) lower plate rotatable engagement;
The guide rod (212) that both ends connect with flap (213) under the second driven pulley (211) and guide rod respectively;
And the lifting supporting plate (214) on the guide rod (212) is enclosed on, the lifting supporting plate (214) and the elevating lever (202) lower end is fixedly connected.
6. fungal infection automatic tester according to claim 1, it is characterised in that the gripper (3) includes:
The sampling arm (301) that one end is fixedly connected with the elevating lever (202) upper end, sampling arm (301) middle part are provided with Strain transducer;
The gripper shell (302) connected with the sampling arm (301) other end;
And crawl structure, the crawl structure is that have one end to be located in gripper shell (302) respectively two are arranged in a crossed manner Z-shaped pawl (303), two Z-shaped pawl (303) upper ends are connected by spring (304), and lower end relative position is provided with poly- inclined two Fluoride film sensor (305), two Z-shaped pawl (303) infalls are connected by Z-shaped pawl rotary shaft (306), the Z-shaped pawl rotation Rotating shaft (306) and the gripper shell (302) connection, two Z-shaped pawl (303) upper arm centres are equipped with electromagnet (307), electromagnetism The folding of two Z-shaped pawls (303) is realized in the coil disconnection and conducting of iron (307).
7. fungal infection automatic tester according to claim 1, it is characterised in that the concussion unit power transmission machine Structure includes:
The 5th motor (403) on fixed earthquake base (401);
The eccentric shaft (404) that one end is fixedly connected with the 5th motor (403) output shaft;
The second shake table (406) connected with the eccentric shaft (404) other end, the second shake table (406) center are provided with diameter More than the through hole of eccentric shaft (404) diameter, eccentric shaft (404) upper end is inserted into the through hole of the second shake table (406);
The shake table of frame shape first (405) being arranged on the outside of the second shake table (406), first shake table (405) are relative Side wall is connected by a vibrating reed (407) respectively corresponding to the inner side of two side walls and second shake table (406), described The one end of the outside of the first shake table (405) two other side wall respectively with a vibrating reed (407) connects, two vibrating reeds (407) the other end is connected by a support with vibrations base respectively, two vibrating reeds on the outside of the first shake table (405) (407) equal and inner side two vibrating reeds (407) are vertical;
And it is fixed on the 6th motor (408) on the first shake table (405), the 6th motor (408) output shaft and second Rotating disk (402) connects.
8. fungal infection automatic tester according to claim 1, it is characterised in that the hatch unit power transmission machine Structure includes:
It is fixed on the 7th motor (504) being incubated on base (501);
And the rotating shaft (506) of axis connection, the rotating shaft are exported by gear drive (505) and the 7th motor (504) (506) through being incubated base (501) and connected with incubation base (501) by bearing, rotating shaft (506) upper end and described incubate Device rotating disk (502) is educated to be fixedly connected.
9. fungal infection automatic tester according to claim 1, it is characterised in that the luminous and detection unit includes 405nmLED (507), 490nmLED (508), 405nm narrow band pass filters (509), 490nm narrow band pass filters (510), feedback connect Receive device (511), spectroscope (512) and photodetector (513);405nmLED (507) emits beam by 405nm narrow-band-filters After piece (509), a part of light is received by a feed back receiver (511) on the outside of optical axis, detection bypass light intensity, another Part chief ray passes through reaction utensil (6) after spectroscope (512) transmission, is received by photodetector (513), 490nmLED (508) emit beam after 490nm narrow band pass filters (510), a part of light is connect by another feedback on the outside of optical axis Device (511) to be received to receive, detection bypass light intensity, another part chief ray passes through reaction utensil (6) after spectroscope (512) reflection, Received by photodetector (513), two-way light passes through spectroscope (512) common optical axis.
10. fungal infection automatic tester according to claim 1, it is characterised in that the automatic tester also includes Pedestal (9) and waste material box (8), the loading base (101), sampling base (201), concussion base (401), incubation base (501) it is fixed on waste material box (8) on the pedestal (9), gripper (3) the oscillating motion process passes through the waste material box (8) top.
CN201720966865.2U 2017-08-03 2017-08-03 Fungal infection automatic tester Active CN207108997U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107254405A (en) * 2017-08-03 2017-10-17 长春理工大学 Fungal infection automatic tester
CN113607461A (en) * 2021-08-09 2021-11-05 山东鲲鹏农业发展有限公司 Feed production material loading auxiliary device

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107254405A (en) * 2017-08-03 2017-10-17 长春理工大学 Fungal infection automatic tester
CN113607461A (en) * 2021-08-09 2021-11-05 山东鲲鹏农业发展有限公司 Feed production material loading auxiliary device
CN113607461B (en) * 2021-08-09 2024-06-04 山东鲲鹏农业发展有限公司 Feed production material loading auxiliary device

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