CN207079238U - A kind of device for growth of tumour cell Inhibition test - Google Patents
A kind of device for growth of tumour cell Inhibition test Download PDFInfo
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- CN207079238U CN207079238U CN201720697098.XU CN201720697098U CN207079238U CN 207079238 U CN207079238 U CN 207079238U CN 201720697098 U CN201720697098 U CN 201720697098U CN 207079238 U CN207079238 U CN 207079238U
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- experimental box
- tumour cell
- growth
- inhibition test
- cell inhibition
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Abstract
It the utility model is related to tumour medicine development field, specifically disclose a kind of device for growth of tumour cell Inhibition test, including experimental box, the experimental box is provided with ventilating system and thermostatic control system, the ventilating system includes air inlet unit and wind unit, and the experimental box front is hinged with experiment chamber door；The thermostatic control system includes temperature sensor, controller and electric heater unit, and the temperature sensor is electrically connected controller, and the controller is electrically connected electric heater unit；The experimental box internal backplane is provided with blake bottle putting hole, and the blake bottle putting hole is placed with blake bottle.The utility model is by reasonably designing, efficiently control gas concentration lwevel and temperature, so that tumour cell is in preferable experimental situation when by medicine culture, the calculating of tumor living cell rate and the drafting of S-shaped dose-effect curve are not influenceed, the result evaluation entirely tested is accurate, greatly increases experiment precision.
Description
Technical field
Tumour medicine development field is the utility model is related to, is used for growth of tumour cell Inhibition test more particularly to one kind
Device.
Background technology
In antitumor research, there has been proposed tumour multi-step, DNA mutation, Apoptosis, cell cycle core engine
Many theoretical and theories such as system, cell cycle start and a plurality of signal transduction pathway participates in.
The research and development of antineoplastic are with the renewal of theory and the progress of technology, from the killing for target spot with nucleic acid etc.
Hinder research of the type Cytotoxic drugs steering to tumour novel targets.Including chemoprophylactic drug, differentiating inducer, inducer of apoptosis, signal
Block agent, angiogenesis inhibitors, biological regulator etc..
Among antitumor developmental research, the experimental study that detection medicine suppresses to growth of tumour cell is one important
Research project.Existing generally use dye exclusion method detection medicine suppresses to growth of tumour cell.With dye exclusion method
, it is necessary to which tumour cell is cultivated under certain gas concentration lwevel and temperature conditionss after by medicine when being tested.
Among existing laboratory apparatus, no special overall device supporting for growth of tumour cell Inhibition test,
When being tested, gas concentration lwevel and temperature can not be efficiently controlled so that tumour cell can not when by medicine culture
Get a desired effect, influence the calculating of tumor living cell rate and the drafting of S-shaped dose-effect curve, and then influence whole real
The result evaluation tested, so as to cause experiment precision low.
Utility model content
The technical problems to be solved in the utility model is to overcome the shortcomings of the prior art, there is provided it is thin that one kind is used for tumour
The device of intracellular growth Inhibition test.
In order to solve the above-mentioned technical problem, the utility model uses following technical scheme：
A kind of device for growth of tumour cell Inhibition test, including experimental box, the experimental box are provided with ventage
System and thermostatic control system, the ventilating system include air inlet unit and wind unit, and the air inlet unit includes being used for toward real
The intake stack of air-supply, the intake stack are arranged in the experimental box side wall in tryoff, and the wind unit includes being used for
The exhaust duct that experimental box inner air is released, the exhaust duct are arranged on the experimental box roof；The experimental box
Front is hinged with experiment chamber door；The thermostatic control system includes temperature sensor, controller and electric heater unit, the temperature
Degree sensor is located on experiment chamber interior wall, and the temperature sensor is electrically connected controller, and the controller is electrically connected electric heater unit；Institute
State experimental box internal backplane and be provided with blake bottle putting hole, the blake bottle putting hole is placed with blake bottle.
Preferably, the experimental box inner roof wall is provided with vavuum pump.
Preferably, described intake stack one end is stretched into inside experimental box through the experimental box side wall, other end connection
Gas storage tank.
Preferably, described exhaust duct one end is stretched into inside experimental box through the experimental box roof, other end connection
Emission-control equipment.
Preferably, the electric heater unit is electrothermal tube, the experimental box bottom is provided with heating interlayer, the electric heating
Pipe is arranged in the heating interlayer.
Preferably, the thermostatic control system includes LED display and input button, the LED display is electrically connected institute
State controller, the input button is electrically connected the controller, and the LED display and input button are arranged at the experimental box
On.
Preferably, the blake bottle putting hole is 1~10, blake bottle is placed with each blake bottle putting hole.
Preferably, the controller electrical connection temperature alarming device, the temperature alarming device are fixed on the experiment
On case lateral wall.
Preferably, timing alarm clock is fixed with the experimental box.
Preferably, the experiment chamber door is provided with door handle.
Beneficial effect is：The utility model efficiently controls gas concentration lwevel and temperature by reasonably designing,
So that tumour cell is in preferable experimental situation when by medicine culture, calculating and the S-shaped of tumor living cell rate are not influenceed
The drafting of dose-effect curve, the result evaluation entirely tested is accurate, greatly increases experiment precision.
Brief description of the drawings
, below will be right in order to illustrate more clearly of the utility model embodiment or technical scheme of the prior art
The required accompanying drawing used is briefly described in embodiment or description of the prior art.In all of the figs, it is similar
Element or part are typically identified by similar reference.In accompanying drawing, each element or part might not be according to the ratios of reality
Draw.
Fig. 1 is a kind of structural representation of device for growth of tumour cell Inhibition test of the utility model；
Fig. 2 is a kind of front view of device for growth of tumour cell Inhibition test of the utility model；
Fig. 3 is a kind of upward view of device for growth of tumour cell Inhibition test of the utility model；
Fig. 4 is the utility model Fig. 3 A-A sectional views；
In figure, 1 is experimental box, and 2 be air inlet unit, and 201 be intake stack, and 202 be gas storage tank, and 3 put for blake bottle
Hole is put, 4 be experiment chamber door, and 401 be door handle, and 5 be wind unit, and 501 be exhaust duct, and 502 be emission-control equipment, and 6 are
LED display, 7 be input button, and 8 be timing alarm clock, and 9 be heating interlayer, and 10 be electrothermal tube, and 11 be blake bottle.
Embodiment
The utility model is described further presently in connection with Figure of description.
As depicted in figs. 1 and 2, a kind of device for growth of tumour cell Inhibition test, including experimental box 1, the reality
Tryoff 1 is provided with ventilating system and thermostatic control system, and the ventilating system includes air inlet unit 2 and wind unit 5, it is described enter
Wind unit 2 includes being used for the intake stack 201 toward air-supply in experimental box 1, and the intake stack 201 is arranged on the experimental box 1
In side wall, the wind unit 5 includes being used for the exhaust duct 501 for releasing the inner air of experimental box 1, the exhaust duct
501 are arranged on the roof of experimental box 1；The front of experimental box 1 is hinged with experiment chamber door 4；The thermostatic control system bag
Temperature sensor, controller and electric heater unit are included, the temperature sensor is fixed on the inwall of experimental box 1, the temperature
Sensor is electrically connected controller, and the controller is electrically connected electric heater unit；The internal backplane of experimental box 1 is placed provided with blake bottle
Hole 3, the blake bottle putting hole are placed with blake bottle 11.
Tumour cell after by medicine is cultivated in experimental box, according to being actually needed intake stack 201 toward in experimental box 1
Corresponding gas is provided, the present embodiment selection is passed through carbon dioxide content as 5% air；Before being cultivated, first lead to one section
Time carbon dioxide content is 5% air, and the air being passed through is discharged from exhaust duct 501, can so ensured in experimental box
The air of former remaining is discharged, and gas meets experimental gas requirement in experimental box 1；Thermostatic control system can control warm in experimental box
Degree, temperature sensor are fixed on the inwall of experimental box 1, test experience case internal temperature, and temperature signal is converted into electric pulse letter
Transmitted after number to controller, controller integrates electric impulse signal control electric heater unit, to maintain the internal temperature of experimental box 1 to be in
The temperature of requirement of experiment.
Preferably, the inner roof wall of experimental box 1 is provided with vavuum pump (not shown).It is real for the reduction of minimumization
Influence of the internal residual gas of tryoff 1 to growth of tumour cell Inhibition test, vavuum pump is designed, will be vacuumized inside experimental box 1
Ventilated again afterwards.
Preferably, described one end of intake stack 201 is stretched into inside experimental box 1 through the experimental box side wall, the other end
Gas storage tank 202 is connected, gas storage tank 202 facilitates toward in experimental box 1 built with the air that carbon dioxide content is 5%
Ventilation, improve conventional efficient.
Preferably, described one end of exhaust duct 501 is stretched into inside experimental box 1 through the roof of experimental box 1, the other end
Connect emission-control equipment 502.Purpose primarily to remove discharge gas among harmful substance, avoid to test Interior Space
Gas pollutes, and protects the safety of staff.
Preferably, as shown in Figure 3 and Figure 4, the electric heater unit is electrothermal tube 10, the bottom of experimental box 1 is set
There is heating interlayer 9, the electrothermal tube 10 is arranged in the heating interlayer 9.When temperature is less than requirement of experiment, controller control
Electrothermal tube 10 works, and lifts temperature in experimental box 1 so that temperature maintains a relatively stable state in experimental box 1.
Preferably, as shown in figure 1, the thermostatic control system includes LED display 6 and input button 7, the LED
Display screen 6 is electrically connected the controller, and the input button 7 is electrically connected the controller, and the LED display 6 and input button 7 are equal
It is arranged on the experimental box 1.The temperature that LED display 6 can be detected with displays temperature sensor, input button 7 are used for defeated
Enter the temperature range in signal setting experimental box 1.
Preferably, in order to be tested simultaneously, the blake bottle putting hole 3 is 1~10, and each blake bottle is put
Put Kong Shangjun and be placed with blake bottle 11.Especially, tested for difference by what the growth of tumour cell of concentration suppressed, Duo Gepei
Support bottle 11 to be placed under identical experimental situation, carry out simultaneously, improve conventional efficient and precision.
Preferably, the controller electrical connection temperature alarming device, the temperature alarming device are fixed on the experiment
On the lateral wall of case 1.When temperature is in abnormal condition for a long time, temperature alarming device alarm.
Preferably, as shown in figure 1, timing alarm clock 8 is fixed with the experimental box 1.Tumour cell generally after by medicine
Incubation time is 36h~48h, and staff can not possibly keep and be waited before experimental box, designs a timing alarm clock 8, can train
When supporting time arrival, give and remind.
Preferably, opening and closing experiment chamber door 4, the experiment chamber door 4 are provided with door handle 401 for convenience.
It can be drawn by above-described embodiment：The utility model efficiently controls dense carbon dioxide by reasonably designing
Degree and temperature so that tumour cell is in preferable experimental situation when by medicine culture, does not influence tumor living cell rate
Calculating and the drafting of S-shaped dose-effect curve, the result evaluation entirely tested is accurate, greatly increases experiment precision.
Various embodiments above is only to illustrate the technical solution of the utility model, rather than its limitations；Although with reference to foregoing
The utility model is described in detail each embodiment, it will be understood by those within the art that：It still can be with
Technical scheme described in foregoing embodiments is modified, either which part or all technical characteristic are equal
Replace；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the utility model technical side
The scope of case, it all should cover among claim of the present utility model and the scope of specification.
Claims (10)
1. a kind of device for growth of tumour cell Inhibition test, including experimental box, it is characterised in that：Set on the experimental box
There are ventilating system and thermostatic control system, the ventilating system includes air inlet unit and wind unit, and the air inlet unit includes
For being arranged on toward the intake stack blown in experimental box, the intake stack in the experimental box side wall, the wind unit
Including the exhaust duct for experimental box inner air to be released, the exhaust duct is arranged on the experimental box roof；Institute
State experimental box front and be hinged with experiment chamber door；The thermostatic control system includes temperature sensor, controller and electrical heating dress
Put, the temperature sensor is located on experiment chamber interior wall, and the temperature sensor is electrically connected controller, the controller be electrically connected electricity plus
Thermal；The experimental box internal backplane is provided with blake bottle putting hole, and the blake bottle putting hole is placed with blake bottle.
A kind of 2. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：The reality
Tryoff inner roof wall is provided with vavuum pump.
A kind of 3. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：It is described enter
Wind pipeline one end is stretched into inside experimental box through the experimental box side wall, other end connection gas storage tank.
A kind of 4. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：The row
Wind pipeline one end is stretched into inside experimental box through the experimental box roof, other end connection emission-control equipment.
A kind of 5. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：The electricity
Heater is electrothermal tube, and the experimental box bottom is provided with heating interlayer, and the electrothermal tube is arranged in the heating interlayer.
A kind of 6. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：The perseverance
Temperature control system includes LED display and input button, and the LED display is electrically connected the controller, the input button electricity
The even controller, the LED display and input button are arranged on the experimental box.
A kind of 7. device for growth of tumour cell Inhibition test according to claim 6, it is characterised in that：The control
Device processed electrically connects temperature alarming device, and the temperature alarming device is fixed on the experimental box lateral wall.
A kind of 8. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：The training
It is 1~10 to support bottle putting hole, and blake bottle is placed with each blake bottle putting hole.
A kind of 9. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：The reality
Timing alarm clock is fixed with tryoff.
A kind of 10. device for growth of tumour cell Inhibition test according to claim 1, it is characterised in that：It is described
Experiment chamber door is provided with door handle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720697098.XU CN207079238U (en) | 2017-06-15 | 2017-06-15 | A kind of device for growth of tumour cell Inhibition test |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720697098.XU CN207079238U (en) | 2017-06-15 | 2017-06-15 | A kind of device for growth of tumour cell Inhibition test |
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| Publication Number | Publication Date |
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| CN207079238U true CN207079238U (en) | 2018-03-09 |
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| CN201720697098.XU Active CN207079238U (en) | 2017-06-15 | 2017-06-15 | A kind of device for growth of tumour cell Inhibition test |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108715808A (en) * | 2018-06-06 | 2018-10-30 | 太原师范学院 | A kind of device for growth of tumour cell Inhibition test |
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2017
- 2017-06-15 CN CN201720697098.XU patent/CN207079238U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108715808A (en) * | 2018-06-06 | 2018-10-30 | 太原师范学院 | A kind of device for growth of tumour cell Inhibition test |
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| CP02 | Change in the address of a patent holder |
Address after: 300457 Room 502, 5 / F, building 2, science and technology development center, No. 4, Dongting 1st Street, Tianjin Economic and Technological Development Zone, Binhai New Area, Tianjin Patentee after: Tianjin crown Pharmaceutical Technology Co., Ltd. Address before: 300457 Tianjin economic and Technological Development Zone Dongting Road No. 220 Tianjin international joint Academy of biological medicine experimental building, floor 14, S1424 Patentee before: Tianjin crown Pharmaceutical Technology Co., Ltd. |
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