CN207050420U - A kind of lyophilized pallet of freeze dryer - Google Patents

A kind of lyophilized pallet of freeze dryer Download PDF

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Publication number
CN207050420U
CN207050420U CN201720741297.6U CN201720741297U CN207050420U CN 207050420 U CN207050420 U CN 207050420U CN 201720741297 U CN201720741297 U CN 201720741297U CN 207050420 U CN207050420 U CN 207050420U
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China
Prior art keywords
lyophilized
bottle
main body
hole slot
metal tray
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CN201720741297.6U
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Chinese (zh)
Inventor
朱国峰
毕利军
张晓莉
冯欣怡
邓丽华
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Guangdong Yuntian Antibody Biotechnology Co Ltd
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Guangdong Yuntian Antibody Biotechnology Co Ltd
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Abstract

The utility model provides a kind of lyophilized pallet of freeze dryer.The lyophilized pallet includes metal tray main body and sets the spacing column in metal tray main body;The metal tray main body is provided with the hole slot for being used for placing lyophilized bottle, and the shape of the hole slot matches with lyophilized bottle and the inwall of the hole slot is in contact with lyophilized bottle, with to freezing bottle uniformly transfer heat;The height of the spacing column is equal with the height of lyophilized bottle, and the tamponade plate of freeze dryer is excessive to the pressure for freezing bottle during preventing that tamponade from operating.The lyophilized pallet can directly deposit lyophilized bottle in the metal tray main body, and be integrally placed in freeze dryer and carry out in situ lyophilized, convenience ease in use, can improve effectively to lyophilized bottle uniformly transfer heat and freeze efficiency when lyophilized.The utility model applies also for the programs such as the precooling in the packing, transhipment, freeze-drying process of bottled medicinal liquor, simplifies the operation sequence of existing pallet.

Description

A kind of lyophilized pallet of freeze dryer
Technical field
Freeze dryer technology field is the utility model is related to, more particularly, to a kind of lyophilized pallet of freeze dryer.
Background technology
Freeze dryer cillin bottle(Lyophilized bottle)Lyophilized pallet is essential in cillin bottle freeze-drying prods production process Transfer tool, canned good cillin bottle is transported in freeze dryer, and it is convenient lyophilized after product taken out from freeze dryer and Follow-up transport process.At present, domestic conventional penicillin bottle transferring tray is the rectangular groove structure of openings at one side, will be canned good Cillin bottle is transported to when on the shelf of freeze dryer out of transferring pallet, it is necessary to which one end of transferring pallet opening first is close into freeze dryer Dividing plate, and make the surface of the bottom plate of transferring pallet and the shelf of freeze dryer in one plane, could be by freeze-drying frame together with XiLin Bottle is pushed out on freeze-drying machine partition board from pallet.Similarly, it is similar process that the cillin bottle after will be lyophilized, which is released,.This transhipment Mode has the following disadvantages:1)Need whether bottom plate and the surface of dividing plate of operating personnel's range estimation transferring pallet are concordant, and personnel are near Distance contact cillin bottle, does not meet hygienic requirements.2)Operating personnel are needed firmly just to can guarantee that the openend of transferring pallet forward It is close to freeze-drying machine partition board, it is time-consuming and laborious, and easily cause toppling over for cillin bottle.Therefore, the pallet operation journey of freeze dryer at present Sequence is cumbersome, and potential safety hazard be present.
In addition, the freeze temperature of freeze dryer is uneven, lyophilized efficiency is had a strong impact on.Specifically, it is freeze-dried in product During, because cillin bottle is placed in the diverse location of framework, the heat transfer of bottle is also variant, is placed in the medicine in centre position Product, due to barrier of the bottle to heat transfer around, its heat transfer is caused mainly to be carried out by bottom of bottle.And close on XiLin of framework Bottle, except bottom thermal transfer also suffers from the influence of framework heat.Medicine bottle close to framework can conduct heat faster, and rate of drying is faster. So, it is necessary to lengthen the time of a lyophilization during freeze-drying, otherwise among cillin bottle due to not fully charge just Into redrying, the local melting of the inside product bottom can be caused, cause product rejection.Lyophilized technique is producing for product During quality and cost impact it is very big.At present, the freeze temperature in freeze dryer is uneven, has a strong impact on lyophilized efficiency, and And existing pallet operation program is cumbersome, and potential safety hazard be present.
Utility model content
The utility model is the defects of overcoming described in above-mentioned prior art, there is provided a kind of lyophilized pallet of freeze dryer.
In order to solve the above technical problems, the technical solution adopted in the utility model is:
It is spacing vertical on a kind of lyophilized pallet of freeze dryer, including metal tray main body and setting metal tray main body Post;The metal tray main body is provided with the hole slot for being used for placing lyophilized bottle, and the shape of the hole slot matches with lyophilized bottle and institute The inwall for stating hole slot is in contact with lyophilized bottle, with to freezing bottle uniformly transfer heat;The height of the spacing column and the height of lyophilized bottle Spend equal, the tamponade plate of freeze dryer is excessive to the pressure for freezing bottle during preventing that tamponade from operating.
Lyophilized bottle can directly be deposited metal tray main body by lyophilized pallet described in the utility model without frame structure On, and be integrally placed in freeze dryer and carry out in situ lyophilized, convenience ease in use, simplified program.
The utility model applies also for the programs such as the precooling in the packing, transhipment, freeze-drying process of bottled medicinal liquor.For sample Packing, during packing, the function of specimen holder can be served as, make lyophilized bottle be not easy to lodge, make packaging operation simple and efficient, Improve operating efficiency and reduce due to loss caused by bottle lodging.
Because the material of the metal tray main body is metal, and the inwall of the hole slot is in contact with lyophilized bottle so that The lyophilized pallet can be effectively to freezing bottle uniformly transfer heat when lyophilized.Precooling for freezing pallet, is in sample In low temperature environment, ensure stability of the sample in packing and transport process, reduce the activity loss of sample.
The material of the metal tray main body is preferably but not limited to aluminium alloy and stainless steel.Similarly, the spacing column Material can be metal, be preferably but not limited to aluminium alloy and stainless steel.
The lyophilized pallet is provided with spacing column, the use that goes for having the freeze-drier of automatic gland function or Person is that manual gland operation is carried out with cover clamp, and it ensures to prevent that the dynamics of tamponade is excessive and crushes bottle during tamponade Body.Preferably, the quantity of the spacing column is at least 2.Preferably 2 ~ 4.
In order that the metal tray main body uniform force.It is highly preferred that the spacing column is separately positioned on the gold Belong to the both sides of tray main body.When being rectangle for metal tray main body, it is highly preferred that the spacing column be separately positioned on it is described Metal tray main body it is diagonal on.
Preferably, the shape of the spacing column matches with the hole slot so that the spacing column can be placed in described In hole slot, to realize that the spacing column is detachably connected with metal tray main body.The spacing column and metal tray main body It is detachably connected so that can select using spacing column or adjust the position of spacing column according to actual conditions.
Preferably, the hole slot is staggered in the metal tray main body.The staggered of the hole slot can either The bottle carrying capacity of lyophilized pallet is improved to greatest extent, and and can ensures that the heat transfer of each hole slot is uniformly effective.
Preferably, the hole slot is provided with the arrival end by fillet processing.It is above-mentioned to be designed to protect lyophilized bottle, avoid pair Scraped in bottle.It is highly preferred that the arrival end is to be handled by 0.5 × 45 ° of fillet.
Preferably, the spacing column also passes through fillet processing, is preferably handled by 0.5 × 45 ° of fillet, to prevent Scratching is produced to the inner surface of the hole slot.
Preferably, two sides of the metal tray main body, which correspond to, is provided with fluting at the hole slot, freeze in order to observe The freezing situation of sample in dry bottle, or be easy to grip in the lyophilized pallet of transfer.
Preferably, the both sides of the metal tray main body are provided with the crossbeam of latch closure or protrusion, in order to the transfer of pallet.
Preferably, the depth value of the hole slot is the 40% ~ 90% of the height value of lyophilized bottle.The depth of the hole slot can protect Card bottle is uprightly placed and is not susceptible to topple over, while meets the needs of heat transfer, is easy to directly taking out for lyophilized bottle again.
Compared with prior art, the beneficial effects of the utility model are:
Lyophilized pallet described in the utility model can directly deposit lyophilized bottle in the metal tray main body, and integrally It is placed in freeze dryer and carries out in situ lyophilized, convenience ease in use, can be effectively to lyophilized bottle uniformly transfer heat, raising when lyophilized Lyophilized efficiency.The utility model applies also for the programs such as the precooling in the packing, transhipment, freeze-drying process of bottled medicinal liquor, simplifies existing There is the operation sequence of pallet.
Brief description of the drawings
Fig. 1 is the structural representation that pallet is freezed described in embodiment 1.
Fig. 2 is the side view that pallet is freezed described in embodiment 1.
Fig. 3 is the front view of spacing column described in embodiment 1.
Fig. 4 is the top view of spacing column described in embodiment 1.
Embodiment
With reference to embodiment, the present invention is further illustrated.Wherein, being given for example only property of accompanying drawing illustrates, What is represented is only schematic diagram, rather than pictorial diagram, it is impossible to is interpreted as the limitation to this patent;In order to which the reality of the present invention is better described Example is applied, some parts of accompanying drawing have omission, zoomed in or out, and do not represent the size of actual object;To those skilled in the art For, some known features and its explanation may be omitted and will be understood by accompanying drawing.
Embodiment 1
As shown in Fig. 1 ~ 4, a kind of lyophilized pallet of freeze dryer, including metal tray main body 100 and setting metal tray Spacing column 200 in main body.The material of metal tray main body 100 and spacing column 200 is preferably but not limited to aluminium alloy and not Become rusty steel.
Metal tray main body 100 is provided with the hole slot 110 for being used for placing lyophilized bottle, the shape of hole slot 110 and lyophilized bottle phase Match somebody with somebody and the inwall of hole slot 110 is in contact with lyophilized bottle, with to freezing bottle uniformly transfer heat.Hole slot 110 is staggered in metal tray In main body 100.Hole slot 110 be provided with by fillet processing arrival end 111, in the present embodiment, arrival end 111 preferable through 0.5 × 45 ° of fillet processing.The depth value of hole slot 110 is the 40% ~ 90% of the height value of lyophilized bottle.The depth of hole slot 110 can Ensure that bottle is uprightly placed and is not susceptible to topple over, while meet the needs of heat transfer, be easy to directly taking out for lyophilized bottle again.Gold Two sides for belonging to tray main body 100 correspond to provided with fluting 120 at hole slot 110, in order to observe the freezing of sample in lyophilized bottle Situation, or be easy to grip in the lyophilized pallet of transfer.
The height of spacing column 200 is equal with the height of lyophilized bottle, the tamponade plate pair of freeze dryer during preventing that tamponade from operating The pressure of lyophilized bottle is excessive.The quantity of spacing column 200 is at least 2, can be configured according to actual conditions, preferably 2 ~ 4 Root.Spacing column 200 is separately positioned on the both sides of metal tray main body 100.In the present embodiment, for metal tray main body 100 when being rectangle, spacing column 200 be separately positioned on metal tray main body 100 it is diagonal on.The shape of spacing column 200 with Hole slot matches so that spacing column 200 can be placed in hole slot, to realize that spacing column 200 and metal tray main body 100 are removable Unload connection so that can select using spacing column 200 or adjust the position of spacing column according to actual conditions.
The both sides of metal tray main body 100 are provided with the crossbeam of latch closure or protrusion, in order to the transfer of pallet.
The specific dimensional parameters that pallet is freezed in the present embodiment are as follows:
Hole slot 110 is shaped as cylinder, a diameter of 16.5 mm of cylindrical hole slot, in staggered, cylindrical hole slot Between line space be 18.5 mm, column pitch is 16.02 mm, to ensure that the distance between each two hole slot is equal, is ensured each Heat transfer indifference between hole slot.The total height of cylindrical hole slot 110 is 23 mm.Cylindrical hole slot is suitable for overall diameter The lyophilized bottle that 16 mm, liquid amount are about 1 ml, body of the lyophilized bottle highly are 36 mm, body jump a queue after be highly 36.1 mm.Accordingly, spacing column is cylinder, is highly 36.1 mm, a diameter of 16 mm.
The concrete operations example of above-mentioned lyophilized pallet is as follows:
1)Lyophilized pallet is entirely placed on the min of precooling 30 in 4 DEG C of refrigerators, is placed in after taking-up in horizontal table top, by cumulative volume For 3 ml, a diameter of 16 mm, be highly that 36 mm lyophilized bottle is placed in the hole slot of circular columns, and in pair of metal tray main body Diagonal position places 2 ~ 4 spacing columns, 1 ml decoction is then dispensed in each lyophilized bottle using liquid-transfering gun, then by glue Match is covered on lyophilized bottle.
2)By the lyophilized pallet equipped with lyophilized bottle, after picking-up, it is transferred on freeze dryer, carries out follow-up lyophilized operation.
Obviously, above-described embodiment of the present utility model is only intended to clearly illustrate the utility model example, and It is not the restriction to embodiment of the present utility model.For those of ordinary skill in the field, in described above On the basis of can also make other changes in different forms.There is no need and unable to give all embodiments It is exhaustive.All made within spirit of the present utility model and principle all any modification, equivalent and improvement etc., should be included in Within the protection domain of the utility model claims.

Claims (9)

1. the lyophilized pallet of a kind of freeze dryer, it is characterised in that including metal tray main body and set in metal tray main body Spacing column;The metal tray main body is provided with the hole slot for being used for placing lyophilized bottle, the shape of the hole slot and lyophilized bottle phase Match and the inwall of the hole slot is in contact with lyophilized bottle, with to freezing bottle uniformly transfer heat;The height and jelly of the spacing column The height of dry bottle is equal, and the tamponade plate of freeze dryer is excessive to the pressure for freezing bottle during preventing that tamponade from operating.
2. lyophilized pallet according to claim 1, it is characterised in that the quantity of the spacing column is at least 2.
3. lyophilized pallet according to claim 2, it is characterised in that the spacing column is separately positioned on the metal support The both sides of disc main body.
4. lyophilized pallet according to claim 3, it is characterised in that the spacing column is separately positioned on the metal support Disc main body it is diagonal on.
5. the lyophilized pallet according to any one of claim 1 ~ 4, it is characterised in that the shape of the spacing column with it is described Hole slot matches so that the spacing column can be placed in the hole slot, to realize the spacing column and metal tray main body It is detachably connected.
6. lyophilized pallet according to claim 1, it is characterised in that the hole slot is staggered in the metal tray master On body.
7. lyophilized pallet according to claim 1, it is characterised in that the hole slot is provided with the entrance by fillet processing End.
8. lyophilized pallet according to claim 1, it is characterised in that the both sides of the metal tray main body be provided with latch closure or The crossbeam of protrusion, in order to freeze the transfer of pallet.
9. lyophilized pallet according to claim 1, it is characterised in that two sides of the metal tray main body correspond to institute State and fluting is provided with hole slot.
CN201720741297.6U 2017-06-23 2017-06-23 A kind of lyophilized pallet of freeze dryer Active CN207050420U (en)

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CN201720741297.6U CN207050420U (en) 2017-06-23 2017-06-23 A kind of lyophilized pallet of freeze dryer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720741297.6U CN207050420U (en) 2017-06-23 2017-06-23 A kind of lyophilized pallet of freeze dryer

Publications (1)

Publication Number Publication Date
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110081676A (en) * 2019-04-30 2019-08-02 成都朴名生物科技有限公司 A kind of bearing support for freeze-drying
CN113124650A (en) * 2019-12-31 2021-07-16 苏州博福生物医药科技有限公司 Freeze-drying method of capture screen
CN113790593A (en) * 2021-06-23 2021-12-14 上海简逸生物科技有限公司 Penicillin bottle freeze-drying support

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110081676A (en) * 2019-04-30 2019-08-02 成都朴名生物科技有限公司 A kind of bearing support for freeze-drying
CN113124650A (en) * 2019-12-31 2021-07-16 苏州博福生物医药科技有限公司 Freeze-drying method of capture screen
CN113124650B (en) * 2019-12-31 2022-05-06 江苏汇先医药技术有限公司 Freeze-drying method of capture screen
CN113790593A (en) * 2021-06-23 2021-12-14 上海简逸生物科技有限公司 Penicillin bottle freeze-drying support

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