CN206945627U - A kind of saliva collecting device - Google Patents
A kind of saliva collecting device Download PDFInfo
- Publication number
- CN206945627U CN206945627U CN201720703672.8U CN201720703672U CN206945627U CN 206945627 U CN206945627 U CN 206945627U CN 201720703672 U CN201720703672 U CN 201720703672U CN 206945627 U CN206945627 U CN 206945627U
- Authority
- CN
- China
- Prior art keywords
- collecting device
- tube
- centrifugation
- saliva
- funnel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
It the utility model is related to a kind of saliva collecting device, belong to Experiment of Analytical Chemistry apparatus field, the device includes centrifugation body, lid, the inner tube in centrifuge tube body and the chromatography column feed materials bottle located at interior bottom of the tube on centrifugation body, said inner tube includes tube chamber, the funnel located at tube chamber bottom, filter membrane is provided between tube chamber bottom and funnel, funnel lower end connects with chromatography column feed materials bottle.Human saliva sample can directly be gathered by device of the present utility model, effectively saliva sample can be avoided to be contaminated in gatherer process, and after being handled by high speed centrifugation, the interference such as residue, macro-molecular protein and impurity in saliva sample can effectively be removed, obtained clarification saliva sample can be directly used for chromatography column feed materials analysis, have the advantages that simple to operate, processing is quick, clean hygiene, easily stored with transporting.
Description
Technical field
A kind of harvester is the utility model is related to, especially a kind of saliva collecting device, belongs to Experiment of Analytical Chemistry and sets
Standby field.
Background technology
Saliva has the characteristics of many is better than blood and urine, such as gathers simple side as a kind of body fluid of Non-Invasive
Just, safe painless, subject is easy to receiving, the infection that can avoid haematogenous etc..Its as a kind of human-body biological body fluid, by
Increasing researcher is as research and the object of medical diagnosis.
In the research process of smoke chemistry, researcher has found：Contain up to thousands of kinds of chemical compositions in cigarette smoke, this
A little compounds are distributed widely in gas phase and the granule phase substance of flue gas aerosol, are connect by the oral cavity with consumer, nasal cavity, respiratory tract
Touch and cause different sensory experiences.Oral cavity contacts the organ of cigarette smoke as human body at first, to the organoleptic quality evaluations of cigarette
Play an important role, and the basis of consumer's recognition and acceptance cigarette product.Saliva is in microenvironment balance is maintained
Play important adjustment effect, in saliva the change of chemical composition content may result in oral cavity and produce different impressions.Therefore,
Effective collection to human saliva sample and the accurate detection to wherein chemical composition are for physiology sense organ caused by research cigarette
Impression has important practical significance.
At present, in process of experimental frequently with saliva acquisition method have：Test tube is left and taken in method, swab stick method and mouth naturally
Chew cotton post method etc..Wherein, swab stick method to the oral cavity of subject due to that can cause certain stimulation, so as to cause saliva flow rate
Change, chemical composition analysis may be affected, now less use.Test tube is left and taken method and typically referred to naturally
The test tube of subject's hand held tape funnel, spits into the test tube with funnel by the saliva of naturally secret in oral cavity within a certain period of time
In.Because saliva viscosity is larger, often it is attached on funnel and inboard wall of test tube in gatherer process and examination can not be spat into completely
Guan Zhong, so as to cause larger collection to be lost.And chewing cotton post method is although convenient and swift in mouth, it is easy to be received by subject, but
Cotton post has no chemical composition enrichment in itself, and the loss of detection target is easily caused in saliva gathers, it is accurate to ultimately result in detection
The reduction of exactness.And cotton post also needs to place back in saliva collection pipe progress subsequent treatment, herein mistake after the completion of mastication processes
The pollution of saliva sample is easily caused in journey, irreversible influence is caused on final detection result.Therefore, exploitation it is a kind of it is pollution-free,
Painless sampling, the saliva sample acquisition processing device that collection is complete and pre-treatment is simple and quick are very necessary.
The content of the invention
In order to solve the above technical problems, the purpose of this utility model aims to provide a kind of saliva collecting device, the device can
To realize the painless sampling of saliva sample, pollution-free collection, and chemical analysis can be carried out online after the completion of acquisition step completely
Pre-treatment, process is simple, quick, effective, and gained clarification saliva sample can be directly used for chromatography column feed materials analysis.
The technical solution of the utility model is as follows：
A kind of saliva collecting device, it is characterised in that：Including centrifugation body, located at centrifugation body on lid, located at from
Inner tube in heart body and the chromatography column feed materials bottle located at interior bottom of the tube, said inner tube include tube chamber, the funnel located at tube chamber bottom,
Filter membrane is provided between tube chamber bottom and funnel, funnel lower end connects with chromatography column feed materials bottle.
Further, lid is connected by connecting portion with the centrifugation mouth of pipe.
Further, the centrifuge tube body top is cylinder chamber, and bottom is cone.
Further, centrifuge tube mouth and be nearby provided with supporting part, stretch out to form rib at the top of the tube chamber of inner tube, it is interior
Pipe is placed on supporting part by rib.
Further, filter membrane seals with funnel adhesion.
Further, the supporting part is annular bayonet socket.
Further, the aperture of the filter membrane is 1-450nm.
Further, the volume of described centrifuge tube body is 5-50mL.
Further, chromatography column feed materials bottle is fixed on centrifugation its bottom by elastomeric material；Its lower portion enters through chromatogram
The silica gel of sample bottle cap is stretched into bottle.
Compared with prior art, the utility model has the following advantages that：
（1）Saliva collecting device of the present utility model can conveniently gather the saliva sample or other glutinous of subject
Property sample（Such as blood, tissue liquid）, painless sampling, and clean hygiene have been truly realized, has been easy to be received by subject.
（2）Due to the centrifugation of filter membrane, handled by high speed centrifugation, it is residue that can be in effectively catching saliva sample, big
Molecule protein and impurity etc., avoid its interference to detecting target chemical composition.Also, it is attached on inner tube wall and funnel
On saliva be also together collected together, avoid the sample loss in gatherer process.
（3）On-line chemical analysis pre-treatment can be realized directly as the reception combined apparatus of chemical analysis pre-treatment,
Progress chromatography column feed materials analysis can be directly taken out by flowing ultimately into the clarification saliva sample that chromatography column feed materials bottle obtains, without passing through shifting again
Liquid device such as is drawn, shifted at the operation, be effectively prevent saliva sample and is contaminated in gatherer process.
（4）The present apparatus according to the difference of detection demand, can change the inner tube of the filter membrane of different pore size size, have detection more
Feature.The saliva sample that the utility model device is simple to operate, process is quick, obtains is easily stored with transporting, and effectively reduces
Laboratory operating procedures, reduce experimental error, have very strong science and operability, can be that medical conditions diagnosis be controlled
The correlative study such as treatment, evaluation of the prognosis, human body provides strong technical support and development foundation.
Brief description of the drawings
Fig. 1 is the structural representation of saliva collecting device of the present utility model.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the present embodiment is carried out clear, complete
Site preparation describes, it is clear that described embodiment is only to a part of example of the utility model, rather than the example of whole.Base
Embodiment in the utility model, the institute that those of ordinary skill in the art are obtained under the premise of creative work is not paid
There is other embodiment, belong to the scope of the utility model protection.
The saliva collecting device of the present embodiment, including centrifuge body 8, the lid 1 on centrifugation body 8, located at centrifugation
Inner tube 4 in body and the chromatography column feed materials bottle 9 located at interior bottom of the tube, centrifugation body 8 top are cylinder chamber, and bottom is cone,
Lid 1 is connected by connecting portion 3 with the centrifugation mouth of pipe 2, and inner tube 4 includes tube chamber, the funnel 7 located at tube chamber bottom, tube chamber bottom
Filter membrane 6 is provided between funnel, filter membrane 6 is sealed in tube chamber bottom with the top adhesion of funnel 7, and the bottom of funnel 7 passes through chromatogram
The silica gel of the bottle cap of sample injection bottle 9 is stretched into bottle, and chromatography column feed materials bottle 9 is fixed on centrifugation body 8 bottom by existing elastomeric material 10.
The centrifugation mouth of pipe 2 is nearby provided with annular bayonet socket 5, stretches out to form rib at the top of the tube chamber of inner tube 4, inner tube 4 is placed in by rib
On annular bayonet socket 5, ensure to will not fall off during centrifugation.
Can be according to experiment purpose and the difference of detection object, setting filter sizes are 1-450nm, according to different needs
Select different filter membranes；The volume of centrifugation body 8 can be arranged to 5-50mL according to the difference of saliva collection capacity.Centrifuge body 8, pipe
Lid 1, connecting portion 3, inner tube 4 and funnel 6 are polypropylene material.
Operation principle of the present utility model is as follows：
Inner tube 4 is fixed in centrifuge tube by the annular bayonet socket 5 in centrifuge tube body 8, and subject at the appointed time will
Saliva is spat into inner tube 4, and saliva slowly flows to the surface of filter membrane 6 along inner tube wall.The lid 1 of centrifuge tube is closed, passes through height
Fast centrifuge carries out centrifugal treating to the saliva sample that collects, and the small-molecule substance in saliva passes through filter membrane, along in funnel 7
Wall is flowed ultimately into chromatography column feed materials bottle 9, and obtained clarification saliva sample, which can directly take out, carries out chromatography column feed materials analysis, detects mesh
Mark chemical composition.
Preferred embodiment of the present utility model is the foregoing is only, it is all at this not to limit the utility model
Within the spirit and principle of utility model, any modification, equivalent substitution and improvements made etc., the utility model should be included in
Protection domain within.
Claims (9)
- A kind of 1. saliva collecting device, it is characterised in that：Including centrifugation body, the lid on centrifugation body, located at centrifugation Inner tube in body and the chromatography column feed materials bottle located at interior bottom of the tube, said inner tube include tube chamber, the funnel located at tube chamber bottom, pipe Filter membrane is provided between bottom of chamber portion and funnel, funnel lower end connects with chromatography column feed materials bottle.
- 2. saliva collecting device according to claim 1, it is characterised in that：Lid is connected by connecting portion with the centrifugation mouth of pipe Connect.
- 3. saliva collecting device according to claim 1, it is characterised in that：The centrifuge tube body top is cylinder chamber, Bottom is cone.
- 4. saliva collecting device according to claim 3, it is characterised in that：The centrifugation mouth of pipe is nearby provided with supporting part, inner tube Tube chamber at the top of stretch out to form rib, inner tube is placed on supporting part by rib.
- 5. saliva collecting device according to claim 4, it is characterised in that：Filter membrane seals with funnel adhesion.
- 6. saliva collecting device according to claim 4, it is characterised in that：The supporting part is annular bayonet socket.
- 7. according to the saliva collecting device described in one of claim 1-6, it is characterised in that：The aperture of the filter membrane is 1- 450nm。
- 8. according to the saliva collecting device described in one of claim 1-6, it is characterised in that：The volume of described centrifuge tube body For 5-50mL.
- 9. according to the saliva collecting device described in one of claim 1-6, it is characterised in that：Chromatography column feed materials bottle passes through elastomeric material It is fixed on centrifugation its bottom；The silica gel of its lower portion through chromatography column feed materials bottle cap is stretched into bottle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720703672.8U CN206945627U (en) | 2017-06-16 | 2017-06-16 | A kind of saliva collecting device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720703672.8U CN206945627U (en) | 2017-06-16 | 2017-06-16 | A kind of saliva collecting device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206945627U true CN206945627U (en) | 2018-01-30 |
Family
ID=61364463
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720703672.8U Active CN206945627U (en) | 2017-06-16 | 2017-06-16 | A kind of saliva collecting device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206945627U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110779788A (en) * | 2019-12-03 | 2020-02-11 | 中山大学附属第八医院（深圳福田） | Device and method for purifying urine protein |
-
2017
- 2017-06-16 CN CN201720703672.8U patent/CN206945627U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110779788A (en) * | 2019-12-03 | 2020-02-11 | 中山大学附属第八医院（深圳福田） | Device and method for purifying urine protein |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021536267A (en) | Particle inspection | |
| CN103857346B (en) | For gathering the device of biological sample and corresponding method | |
| CN204484173U (en) | Baby's spittle collector | |
| CN203869913U (en) | Controllable disposable midstream urine specimen collection device | |
| CN207528471U (en) | Novel faeces Acquisition Processor | |
| CN107817123A (en) | Novel faeces Acquisition Processor | |
| CN206945627U (en) | A kind of saliva collecting device | |
| CN103962194A (en) | Excrement liquidizing and filtering test tube | |
| CN103983703A (en) | High-performance-liquid-chromatography detection method for methylene blue in aquaculture water | |
| CN108703775A (en) | A kind of saliva collecting device and saliva acquisition method | |
| CN203502260U (en) | Saliva sampler | |
| CN208043492U (en) | A kind of medicine detection sampler | |
| CN201622188U (en) | Excrement sampler for medical treatment | |
| CN209712979U (en) | A kind of saliva acquisition storage device | |
| CN106860933A (en) | A kind of blood perfusion system | |
| CN204831853U (en) | Saliva is collected and saliva volume metering device | |
| CN107340151A (en) | Fecal sample quantitative collection device and acquisition method | |
| CN103571914B (en) | Obtain acquisition method and the device of nucleic acid clinical samples | |
| CN208000211U (en) | A kind of device of medical inspection section acquisition human excrement and urine | |
| CN203672675U (en) | Medical bad breath collector | |
| CN203658093U (en) | Device for collecting urine sample | |
| CN211511867U (en) | Saliva collection system | |
| CN208838005U (en) | Convenient type urine culture collector | |
| CN204008185U (en) | A kind of disposable sampling pipe | |
| CN105021427B (en) | A kind of saliva collection and saliva liquid volume measurement apparatus and method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant |