CN206823677U - One kind automation cryogenic high pressure homogenizer - Google Patents

One kind automation cryogenic high pressure homogenizer Download PDF

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Publication number
CN206823677U
CN206823677U CN201720706888.XU CN201720706888U CN206823677U CN 206823677 U CN206823677 U CN 206823677U CN 201720706888 U CN201720706888 U CN 201720706888U CN 206823677 U CN206823677 U CN 206823677U
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China
Prior art keywords
pressure
batch
homogenizer
micro controller
expects pipe
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CN201720706888.XU
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Chinese (zh)
Inventor
陈仲巍
洪璇
罗联忠
李鹤宾
曾臻
林启凰
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Xiamen Medical College
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Xiamen Medical College
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Abstract

The utility model discloses one kind to automate cryogenic high pressure homogenizer, including batch can, homogenizer, expects pipe, cooling component, control assembly and micro controller;Batch can is connected with homogenizer by expects pipe to form circulation loop, and control assembly is located in the circulation loop to control feed solution flow;Cooling component is located at outside batch can and expects pipe to be cooled down to feed liquid;Temperature sensor is provided with batch can;Micro controller receives the information of temperature sensor and pressure sensor and controls cooling component, control assembly, the high-pressure homogeneous pump housing and pressure regulation valve events, realizes Automated condtrol, novel in design, easy to use, and intelligence degree is high, it is easy to accomplish, can automation mechanized operation.

Description

One kind automation cryogenic high pressure homogenizer
Technical field
Homogenizer field is the utility model is related to, more particularly to a kind of automation cryogenic high pressure homogenizer.
Background technology
High pressure homogenizer is mainly used in the industries such as biology, medicine, food, chemical industry, carries out clasmatosis, drink homogeneous, essence Work is refined, prepares the products such as liposome, Fat Emulsion, nano suspension, emulsion.Its application field is very extensive, and the whole world has near The market demand of 10000000000 RMB.However, the domestic most of automaticities of high pressure homogenizer are low at present, intelligence degree is not It is enough, it is single to the high-pressure homogeneous process technology of product, generally require supporting other technological means.Although during high-pressure homogeneous Most crucial part is the high-pressure homogeneous pump housing, however, the monitoring to homogenization pressure and to feed temperature also can be largely The quality of product is influenceed, such as when carrying out clasmatosis acquisition intracellular destination protein, the height and stability of homogenization pressure are direct The effect of clasmatosis is had influence on, substantial amounts of heat caused by shattering process directly influences the activity of destination protein, it is necessary to Continuous manual adjustment pressure and being cooled down to feed liquid repeatedly.Manual adjustment control often deposit it is big it is very big it is uncertain because Element, deposits big very big risk to the control of critical process, and discontinuity and inadequate intelligent automation are to the efficiency that entirely produces Bring very big influence.
Therefore, industry is badly in need of a kind of novel automatic cryogenic high pressure homogenizer, unnecessary artificial subjective factor shadow is reduced Ring, save manpower, and ensure the continuity of production, to improve production efficiency and product quality.
Utility model content
In view of the deficienciess of the prior art, to be to provide a kind of novel automatic cryogenic high pressure equal for the purpose of this utility model Matter machine, to solve the problems mentioned in the above background technology, the utility model are novel in design, easy to use, and intelligence degree is high, It is easily achieved, can automation mechanized operation.
The technical scheme that the utility model solves above-mentioned technical problem is as follows:
One kind automation cryogenic high pressure homogenizer, including batch can, homogenizer, expects pipe, cooling component, control assembly and micro- Control device;Batch can is connected with homogenizer by expects pipe to form circulation loop, and control assembly is located in the circulation loop with control Feed solution flow;Cooling component is located at outside batch can and expects pipe to be cooled down to feed liquid;Temperature sensor is provided with batch can;Homogenizer Provided with the high-pressure homogeneous pump housing, pressure regulator valve and pressure sensor;Temperature sensor, pressure sensor, cooling component, control group Part, the high-pressure homogeneous pump housing, pressure regulator valve connect micro controller respectively, and micro controller receives the information of temperature sensor and pressure sensor simultaneously Control cooling component, control assembly, the high-pressure homogeneous pump housing and pressure regulation valve events.
Optionally, the cooling component includes being used for the refrigeration unit and cold for circulation cycle for producing circulating water bath The chuck and cooler of water-bath, refrigeration unit are controlled by the micro controller, and chuck is sheathed on the batch can, described at least part Expects pipe is located in cooler.
Optionally, the expects pipe being located in cooler is to be connected to what the homogenizer exported by the top of the batch can At least a portion in expects pipe, serpentine-like pipe, bulb tube or straight line folding shape pipe are set.
Optionally, the control assembly includes infusion pump, feed valve and outlet valve, and infusion pump and feed valve are located at by described Homogenizer entrance is connected in the expects pipe of the batch can discharging opening and connects the micro controller, and outlet valve discharges located at the expects pipe On mouth and connect the micro controller.
Optionally, the feed valve and outlet valve are auto-manual valves.
Optionally, the micro controller includes the touch screen for man-machine interaction.
Optionally, in addition to alarm, alarm connect the micro controller, and alarm includes LED and buzzer.
The beneficial effects of the utility model are:
In being provided with temperature sensor in batch can, homogenizer is provided with pressure sensor, and micro controller receives temperature sensor and pressure The information of force snesor simultaneously controls cooling component, control assembly, the high-pressure homogeneous pump housing and pressure regulation valve events, realizes automation control System, novel in design, easy to use, intelligence degree is high, it is easy to accomplish, can automation mechanized operation.
Brief description of the drawings
Fig. 1 is overall structure diagram of the present utility model;
Fig. 2 is circuit module schematic diagram of the present utility model.
Embodiment
Principle of the present utility model and feature are described below in conjunction with accompanying drawing, example is served only for explaining this practicality It is new, it is not intended to limit the scope of the utility model.
With reference to figure 1 and Fig. 2, a kind of novel automatic cryogenic high pressure homogenizer includes batch can 1, homogenizer 2, expects pipe 3, cooling Component, control assembly and micro controller 4.Batch can 1 and homogenizer 2 are connected by expects pipe 3 to form circulation loop, and control assembly is set To control feed solution flow in the circulation loop.Cooling component is located at outside batch can 1 and expects pipe 3 to be cooled down to feed liquid.Material Temperature sensor 5 is provided with tank 1.Homogenizer 2 is provided with the high-pressure homogeneous pump housing 21, pressure regulator valve 22 and pressure sensor 6.Temperature passes Sensor 5, pressure sensor 6, cooling component, control assembly, the high-pressure homogeneous pump housing 21, pressure regulator valve 22 connect micro controller 4 respectively, micro- Control device 4 receives the information of temperature sensor 5 and pressure sensor 6 and controls cooling component, control assembly, the high-pressure homogeneous pump housing 21 Acted with pressure regulator valve 22.
The cooling component produces the refrigeration unit of circulating water bath and for circulation cycle cold bath including being used for Chuck 7 and cooler 8, refrigeration unit are controlled by the micro controller 4, and chuck 7 is sheathed on the batch can 1, described at least part Expects pipe 3 is located in cooler 8, is referred to as the expects pipe in cooler 8 to cool down expects pipe below, cooling expects pipe is by the batch can 1 top is connected at least a portion in the expects pipe that the homogenizer 2 exports, serpentine-like pipe, bulb tube or straight line folding shape pipe Set, rolling over shape pipe with reference to figure 1, in the present embodiment for straight line is set.
The control assembly includes infusion pump 9, feed valve 10 and outlet valve 11, and infusion pump 9 and feed valve 10 are located at by institute State the entrance of homogenizer 2 to be connected in the expects pipe 3 of the discharging opening of batch can 1 and connect the micro controller 4, outlet valve 11 is located at described On the discharging opening of expects pipe 3 and connect the micro controller 4.Feed valve 10 and outlet valve 11 are auto-manual valves, can also be carried out artificial Operation.
Batch can 1 is provided with upper lid 101, in order to the liquid that feeds.In the presence of infusion pump 9, feed liquid is by batch can 1 through feed valve 11 It is delivered to homogenizer 2.The high-pressure homogeneous inside of the pump housing 21 has specially designed geometry, high in the presence of booster body For pressure solution liquid quickly by homogeneous chamber, thus material simultaneously by various mechanical forces, can reach the effect of homogeneous.By right The control of valve, feed liquid can be exported by homogenizer 2 to be flowed back to batch can 1 and is circulated through cooling down expects pipe, is realized and is repeated broken homogeneous.
The micro controller 4 can specifically include microprocessor and touch screen, and microprocessor is used to receive, analyze, locate Reason, data command is sent, touch screen is used for the reality for inputting arrange parameter value to the microprocessor and output display monitors When data, in order to man-machine interaction.
Further, in addition to alarm, alarm connect the micro controller, and alarm includes LED and buzzer, in temperature Degree or pressure are alarmed when exceeding preset range.
The utility model realizes that the method for automation cryogenic high pressure homogeneous is:
The first step, control parameter is inputted by the touch screen, the control parameter includes but is not limited to:Feed temperature Up/down limit value, high-pressure homogeneous pressure value etc.;
Second step, the microprocessor start the refrigeration unit and produce circulating water bath, pass through chuck and cooler Batch can and the feed liquid for flowing through expects pipe are cooled down;
3rd step, the temperature sensor measure feed temperature in the batch can, and are sent to the microprocessor;
4th step, the microprocessor analyze the feed temperature that the temperature sensor measures;
5th step, when feed temperature is less than the feed temperature lower limit that control parameter is set, the microprocessor leads to Cross electric connection and automatically open up feed valve, then start the infusion pump, feed liquid is circulated in the material pipe-line system;
6th step, the pressure sensor measure homogenization pressure in the high pressure homogeneous pump body, and real by being electrically connected with When send institute's pressure measurement force value to the microprocessor;
7th step, the microprocessor automatically control the pressure regulator valve to the high-pressure homogeneous pump housing by being electrically connected with Pressurization, and make the control ginseng that homogenization pressure reaches and stably set in the microprocessor in the high pressure homogeneous pump body Several high-pressure homogeneous pressure values;
8th step, when feed temperature is higher than the feed temperature higher limit that control parameter is set, the microprocessor leads to Cross electric connection and automatically control the pressure regulator valve and be decompressed to no homogenization pressure to the high-pressure homogeneous pump housing, nothing is in using feed liquid Pressure cooling recurrent state;
9th step, the 5th step to the 8th step is repeated, until feed liquid homogeneous or degree of fragmentation meet technological requirement;
Tenth step, the microprocessor is by being electrically connected with automatic closing feed valve;
11st step, the homogenizer to be evacuated, the microprocessor close the high pressure automatically by being electrically connected with The homogeneous pump housing;
12nd step, outlet valve is opened, feed liquid is released from the discharging opening of the batch can;
13rd step, by technological requirement, with clear water or washing lotion in the state of without homogenization pressure cleaning equipment and its expects pipe Road system.
Above-described embodiment is only used for further illustrating a kind of automation cryogenic high pressure homogenizer of the present utility model, but this reality Embodiment is not limited to new, every foundation the technical essence of the utility model is made any simple to above example Modification, equivalent variations and modification, each fall within the protection domain of technical solutions of the utility model.

Claims (7)

1. one kind automation cryogenic high pressure homogenizer, it is characterised in that:Including batch can, homogenizer, expects pipe, cooling component, control Component and micro controller;Batch can is connected with homogenizer by expects pipe to form circulation loop, and control assembly is recycled back to located at described To control feed solution flow in road;Cooling component is located at outside batch can and expects pipe to be cooled down to feed liquid;Temperature is provided with batch can to pass Sensor;Homogenizer is provided with the high-pressure homogeneous pump housing, pressure regulator valve and pressure sensor;Temperature sensor, pressure sensor, cooling group Part, control assembly, the high-pressure homogeneous pump housing, pressure regulator valve connect micro controller respectively, and micro controller receives temperature sensor and pressure sensing The information of device simultaneously controls cooling component, control assembly, the high-pressure homogeneous pump housing and pressure regulation valve events.
2. automation cryogenic high pressure homogenizer according to claim 1, it is characterised in that:The cooling component includes being used for Produce the refrigeration unit of circulating water bath and chuck and cooler for circulation cycle cold bath, refrigeration unit are controlled by institute Micro controller is stated, chuck is sheathed on the batch can, and at least partly described expects pipe is located in cooler.
3. automation cryogenic high pressure homogenizer according to claim 2, it is characterised in that:The material being located in cooler Pipe is at least a portion being connected to by the top of the batch can in the expects pipe of homogenizer outlet, serpentine-like pipe, bulb tube Or straight line folding shape pipe is set.
4. automation cryogenic high pressure homogenizer according to claim 1, it is characterised in that:The control assembly includes transfusion Pump, feed valve and outlet valve, infusion pump and feed valve are located at the material that the batch can discharging opening is connected to by the homogenizer entrance On pipe and the micro controller is connected, outlet valve is located on the expects pipe discharging opening and connects the micro controller.
5. automation cryogenic high pressure homogenizer according to claim 4, it is characterised in that:The feed valve and outlet valve are Auto-manual valve.
6. automation cryogenic high pressure homogenizer according to claim 1, it is characterised in that:The micro controller includes being used for people The touch screen of machine interaction.
7. automation cryogenic high pressure homogenizer according to claim 1, it is characterised in that:Also include alarm, alarm The micro controller is connected, alarm includes LED and buzzer.
CN201720706888.XU 2017-06-16 2017-06-16 One kind automation cryogenic high pressure homogenizer Active CN206823677U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201720706888.XU CN206823677U (en) 2017-06-16 2017-06-16 One kind automation cryogenic high pressure homogenizer

Publications (1)

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CN206823677U true CN206823677U (en) 2018-01-02

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112203753A (en) * 2018-06-14 2021-01-08 利乐拉瓦尔集团及财务有限公司 Homogenizer and homogenization method for liquid food

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112203753A (en) * 2018-06-14 2021-01-08 利乐拉瓦尔集团及财务有限公司 Homogenizer and homogenization method for liquid food
CN112203753B (en) * 2018-06-14 2023-03-24 利乐拉瓦尔集团及财务有限公司 Homogenizer and homogenization method for liquid food

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