CN206756843U - A kind of two-in-one immunochromatographiassays assays instrument - Google Patents
A kind of two-in-one immunochromatographiassays assays instrument Download PDFInfo
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- CN206756843U CN206756843U CN201720565616.2U CN201720565616U CN206756843U CN 206756843 U CN206756843 U CN 206756843U CN 201720565616 U CN201720565616 U CN 201720565616U CN 206756843 U CN206756843 U CN 206756843U
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- test strips
- light source
- optical detecting
- controller
- immunochromatographiassays assays
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Abstract
A kind of two-in-one immunochromatographiassays assays instrument, including housing are the utility model is related to, the housing side is provided with test strips socket, and the test strips socket is provided with test strips base towards housing；The case inside bottom is provided with slide unit, and the test strips base is by transmission mechanism on slide unit；Optical detecting module is fixed with the slide unit, the optical detecting module is parallel above test strips base；Testing agency is provided between the test strips base and optical detecting module, the testing agency is connected to controller, and the controller is connected with transmission mechanism and optical detecting module.Different optical detecting modules is integrated together by the utility model, pass through testing agency's Intelligent Recognition colloidal gold strip or fluorescent test paper strip, compact overall structure, it is feature-rich, when in situ quantitation detection demand is more, dual-use, occupy little space, it is simple to operate, meet the needs of multifunction immunity chromatographic analysis.
Description
Technical field
The utility model belongs to using optical instrument, i.e., tests or analyze material using infrared light, visible ray or ultraviolet light
The technical field of material, it is more particularly to a kind of both to have ensured optical detection precision and can on an immunochromatographiassays assays instrument while realized
The two-in-one immunochromatographiassays assays instrument of the detection and analysis of colloidal gold strip and fluorescent test paper strip.
Background technology
At present, immunochromatography（lateral flow immunoassay, LFIA ）Fast Detection Technique is built upon layer
Technology on the basis of analysis technology and Ag-Ab specific immune response.Principal immune chromatographic technique mainly has two kinds at present：Fluorescence
Immunochromatography and colloidal gold chromatographic, immunochromatography Fast Detection Technique can be widely applied in situ quantitation detection, be following instant
The important directions of detection technique development.
The quantitative analysis principle of colloidal gold immune chromatography test is：Test paper bar reaction zone internal reflection luminous intensity, passes through
The reflected light signal amplitude is detected, quantitative detecting analysis can be carried out.General colloid gold test paper analyzer uses green LED conduct
Radiation source, during detection, the detection sample after buffered liquid is fully mixed is added to the well of detection card, the quilt in sample
Analyte forms red immune complex in chromatography process, when green light source is irradiated to the detection zone and quality control region of detection card
Domain, red colloid gold particle absorbs green glow, and reflects feux rouges, and the feux rouges of transmitting is collected and is converted into electric signal, electric signal
Power it is strictly related to emitted luminescence intensity, can analyze the content of measured object in sample to be tested by detecting intensity signal.
The quantitative analysis principle of dry type fluorescence immunoassay test paper is：Fluorescent material can produce stabilization in the case where excitation source excites
The fluorescence signal of light intensity, by detecting the fluorescence signal amplitude, quantitative detecting analysis can be carried out.General dry type fluorescence immunoassay point
Analyzer uses ultraviolet leds as excitation source, and during detection, the detection sample after buffered liquid is fully mixed is added to detection
The well of card, the analyte in sample form immune complex in chromatography process, when excitation source is irradiated to detection card
Detection zone and Quality Control region, excite the fluorescent material of attachment, transmitting light is collected and is converted into electric signal, the power of electric signal
It is strictly related to fluorescence molecule quantity, it can analyze the content of measured object in sample to be tested by detecting intensity signal.
With the development that in situ quantitation detects, immunochromatographiassays assays instrument develops towards multifunctional unit direction, but existing skill
The art of detection and analysis in to(for) colloidal gold strip and fluorescent test paper strip are typically all separately carried out, when in situ quantitation detection demand compared with
, it is necessary to use at least two equipment, space-consuming is big, complex operation when more.
Utility model content
The technical problem that the utility model solves is, in the prior art, with the development that in situ quantitation detects, immunochromatography
Analyzer develops towards multifunctional unit direction, but the detection for colloidal gold strip and fluorescent test paper strip point in the prior art
Analysis is general all separately to be carried out, caused by when in situ quantitation detection demand is more, it is necessary to use at least two equipment, take empty
Between it is big, the problem of complex operation, and then provide a kind of two-in-one immunochromatographiassays assays instrument for optimizing structure.
The utility model is the technical scheme adopted is that a kind of two-in-one immunochromatographiassays assays instrument, including housing, the shell
Body side is provided with test strips socket, and the test strips socket is provided with test strips base towards housing；The case inside bottom is set
There is slide unit, the test strips base is by transmission mechanism on slide unit；Optical detecting module, institute are fixed with the slide unit
It is parallel above test strips base to state optical detecting module；Detection machine is provided between the test strips base and optical detecting module
Structure, the testing agency are connected to controller, and the controller is connected with transmission mechanism and optical detecting module.
Preferably, the transmission mechanism includes motor, and the output shaft of the motor is connected with screw mandrel, the screw mandrel outer sheath
Provided with nut, the screw mandrel is parallel with the slide unit, and the nut is set with the test strips base engagement；The motor and institute
State controller connection.
Preferably, the transmission mechanism also includes the guide rail below test strips base, and the test strips base passes through
Sliding block is equipped with the guide rail, and the guide rail is parallel with the screw mandrel, and the sliding block is connected with the nut.
Preferably, the screw mandrel is provided with the first microswitch relative to one end of motor, the guide rail towards motor one
End is provided with the second microswitch；First microswitch and the second microswitch are connected with the controller.
Preferably, the test strips base includes chute, and the chute is in same level with the test strips socket
On.
Preferably, the optical detecting module includes being used to detect the first detection module of collaurum and for detecting fluorescence
The second detection module；The first detection module includes the first light source and the first photodiode, second detection module
Including secondary light source and the second photodiode.
Preferably, the controller is connected with the first detection module and the second detection module respectively.
Preferably, first light source is green-light source, and the secondary light source is fluorescence excitation light source.
Preferably, the wavelength of first light source is 525nm.
Preferably, the testing agency includes laser scanning light source, and the laser scanning light source is connected to controller.
The utility model provides a kind of two-in-one immunochromatographiassays assays instrument for optimizing structure, by being set in housing side
Test strips socket and correspondingly towards test strips base is set in housing, sets slide unit, test strips base leads in case inside bottom
Cross transmission mechanism to be arranged on slide unit, for importing test strips；Parallel be located above test strips base is fixedly installed on slide unit
Optical detecting module, and set between test strips base and optical detecting module and be connected to the testing agency of controller, by examining
Survey mechanism detection and distinguish that censorship test strips are colloidal gold strip or fluorescent test paper strip, and optics is triggered by the control of controller
Corresponding detection entity detects to censorship test strips in detection module.The utility model is whole by different optical detecting modules
It is combined together, by testing agency's Intelligent Recognition colloidal gold strip or fluorescent test paper strip, compact overall structure is feature-rich,
When in situ quantitation detection demand is more, dual-use, occupy little space, it is simple to operate, meet multifunction immunity chromatographic analysis
Demand.
Brief description of the drawings
Fig. 1 is the three-dimensional figure structure schematic representation of omission housing of the present utility model；
Fig. 2 is the posterior view point solid figure structure schematic representation of omission housing of the present utility model；
Fig. 3 is the blast figure structure schematic representation of omission housing of the present utility model.
Embodiment
The utility model is described in further detail with reference to embodiment, but the scope of protection of the utility model is simultaneously
Not limited to this.
As illustrated, a kind of two-in-one immunochromatographiassays assays instrument is the utility model is related to, including housing, the housing side
Provided with test strips socket, the test strips socket is provided with test strips base 1 towards housing；The case inside bottom is provided with slide unit
2, the test strips base 1 is by transmission mechanism on slide unit 2；Optical detecting module 3, institute are fixed with the slide unit 2
It is parallel located at the top of test strips base 1 to state optical detecting module 3；Inspection is provided between the test strips base 1 and optical detecting module 3
Mechanism is surveyed, the testing agency is connected to controller, and the controller is connected with transmission mechanism and optical detecting module 3.
In the utility model, two-in-one immunochromatographiassays assays instrument includes an integral housing, is set in the side of housing
Test strips socket, test strips socket is corresponding towards setting test strips base 1 in housing, and slide unit 2, examination are set in case inside bottom
Paper slip base 1 is arranged on slide unit 2 by transmission mechanism, and transmission mechanism can be driven the behaviour for being advanced or being retreated by controller
Make, for importing test strips.
In the utility model, the parallel optical detecting module 3 being located above test strips base 1 is fixedly installed on slide unit 2,
And the testing agency for being connected to controller is set between test strips base 1 and optical detecting module 3, detected and distinguished by testing agency
Censorship test strips are colloidal gold strip or fluorescent test paper strip, and right in the control triggering optical detecting module 3 for passing through controller
The detection entity answered detects to censorship test strips.
Different optical detecting modules 3 is integrated together by the utility model, passes through testing agency's Intelligent Recognition collaurum
Test strips or fluorescent test paper strip, compact overall structure is feature-rich, when in situ quantitation detection demand is more, dual-use, accounts for
It is small with space, it is simple to operate, meet the needs of multifunction immunity chromatographic analysis.
The transmission mechanism includes motor 4, and the output shaft of the motor 4 is connected with screw mandrel 5, and the outside of screw mandrel 5 is arranged
There is nut, the screw mandrel 5 is parallel with the slide unit 2, and the nut is equipped with the test strips base 1；The motor 4 with
The controller connection.
The transmission mechanism also includes the guide rail 7 located at the lower section of test strips base 1, and the test strips base 1 passes through sliding block 8
It is equipped with the guide rail 7, the guide rail 7 is parallel with the screw mandrel 5, and the sliding block 8 is connected with the nut.
The screw mandrel 5 is provided with the first microswitch 9 relative to one end of motor 4, and the guide rail 7 is towards one end of motor 4
Provided with the second microswitch 10；The microswitch 10 of first microswitch 9 and second is connected with the controller.
In the utility model, transmission mechanism is used to import test strips base 1.
In the utility model, transmission mechanism includes the motor 4 for driving, and screw mandrel 5 is connected with the output shaft of motor 4,
The outside of screw mandrel 5 is cased with nut, when screw mandrel 5 rotates, drives nut to advance or retreat.
In the utility model, the lower section of test strips base 1 is provided with the guide rail 7 parallel with screw mandrel 5 and is used to be oriented to, when nut advances
Or when retreating, drive the sliding block 8 under test strips base 1 to advance or retreat along guide rail 7, complete the input of test strips and send out to make
Industry.
In the utility model, screw mandrel 5 is provided with the first microswitch 9 relative to one end of motor 4, and guide rail 7 is towards motor 4
One end is provided with the second microswitch 10, and the first microswitch 9 is used for the output length for limiting test strips base 1, and the second fine motion is opened
The 10 feeding depth for being used to limit test strips base 1 are closed, once the first microswitch 9 or the second microswitch 10 are triggered, then
Controller is fed back signal to, controller controlled motor 4 stops output.
The test strips base 1 includes chute 6, and the chute 6 is in same level with the test strips socket.
In the utility model, in order to ensure the accuracy of detection, therefore test strips base 1 includes chute 6, and chute 6 and examination
Paper slip socket is in same level, i.e., test strips can be completed to be embedded in chute 6, ensure that the stability of detection.
The optical detecting module 3 includes being used for the first detection module for detecting collaurum and second for detecting fluorescence
Detection module；The first detection module includes the first light source 11 and the first photodiode 12, the second detection module bag
Include the photodiode 14 of secondary light source 13 and second.
The controller is connected with the first detection module and the second detection module respectively.
First light source 11 is green-light source, and the secondary light source 13 is fluorescence excitation light source.
The wavelength of first light source 11 is 525nm.
In the utility model, optical detecting module 3 includes being used to detect the first detection module of collaurum and for detecting
Second detection module of fluorescence, therefore optical detecting module 3 contains two illuminating sources --- the first light source 11 and secondary light source 13,
And corresponding two photodiodes --- the first photodiode 12 and the second photodiode 14.
In the utility model, controller can individually control first detection module or the second detection module, to trigger difference
Detection pattern.
In the utility model, the first detection module for detecting collaurum includes green-light source, when optical detecting module 3
When switching to the first detection module of detection collaurum, green-light source is lighted, by the corresponding detection light of first photodiode 12
Strong signal.
In the utility model, the second detection module for detecting fluorescence includes fluorescence excitation light source, generally ultraviolet light
Source, when optical detecting module 3 switches to the second detection module of detection fluorescence, ultraviolet sources ignition, by corresponding second light
Electric diode 14 detects light intensity signal.
In the utility model, optical detecting module 3 can be also used for detect sample type, typically use above-mentioned wavelength for
525nm the first light source 11, it can be used for identifying sample type, such as serum, blood plasma, urine.
The testing agency includes laser scanning light source 15, and the laser scanning light source 15 is connected to controller.
In the utility model, testing agency includes laser scanning light source 15, the scanning control test strips of laser scanning light source 15
After information, device processed is fed back to, you can with by the specific optical detecting module 3 of controller control selections.
In the utility model, laser scanning be skilled addressee readily understands that content, including one-dimensional scanning and two
Dimension scanning etc., those skilled in the art can be configured according to the demand of reality.
The utility model solves in the prior art, and with the development that in situ quantitation detects, immunochromatographiassays assays instrument is towards more
Function integrates direction and developed, but the detection and analysis for colloidal gold strip and fluorescent test paper strip typically all divide in the prior art
Drive row into, caused by when in situ quantitation detection demand is more, it is necessary to use at least two equipment, space-consuming is big, operation
The problem of complicated, by setting test strips socket in housing side and correspondingly towards setting test strips base 1 in housing, in housing
Inside bottom sets slide unit 2, and test strips base 1 is arranged on slide unit 2 by transmission mechanism, for importing test strips；In slide unit 2
It is upper that the parallel optical detecting module 3 for being located at the top of test strips base 1 is fixedly installed, and in test strips base 1 and optical detection mould
Set between block 3 and be connected to the testing agency of controller, detected by testing agency distinguish censorship test strips be colloidal gold strip or
Fluorescent test paper strip, and corresponding detection entity enters to censorship test strips in the control triggering optical detecting module 3 for passing through controller
Row detection.Different optical detecting modules 3 is integrated together by the utility model, is tried by testing agency's Intelligent Recognition collaurum
Paper slip or fluorescent test paper strip, compact overall structure is feature-rich, when in situ quantitation detection demand is more, dual-use, takes
Space is small, simple to operate, meets the needs of multifunction immunity chromatographic analysis.
Claims (10)
1. a kind of two-in-one immunochromatographiassays assays instrument, including housing, it is characterised in that：Inserted provided with test strips the housing side
Mouthful, the test strips socket is provided with test strips base towards housing；The case inside bottom is provided with slide unit, the test strips bottom
Seat is by transmission mechanism on slide unit；Optical detecting module is fixed with the slide unit, the optical detecting module is parallel
Above test strips base；Testing agency is provided between the test strips base and optical detecting module, the testing agency connects
Controller is connected to, the controller is connected with transmission mechanism and optical detecting module.
A kind of 2. two-in-one immunochromatographiassays assays instrument according to claim 1, it is characterised in that：The transmission mechanism includes
Motor, the output shaft of the motor are connected with screw mandrel, and the screw mandrel outer sheath is provided with nut, and the screw mandrel is put down with the slide unit
OK, the nut is set with the test strips base engagement；The motor is connected with the controller.
A kind of 3. two-in-one immunochromatographiassays assays instrument according to claim 2, it is characterised in that：The transmission mechanism also wraps
The guide rail below test strips base is included, the test strips base is equipped with by sliding block and the guide rail, the guide rail
Parallel with the screw mandrel, the sliding block is connected with the nut.
A kind of 4. two-in-one immunochromatographiassays assays instrument according to claim 3, it is characterised in that：The screw mandrel is relative to electricity
One end of machine is provided with the first microswitch, and the guide rail is provided with the second microswitch towards one end of motor；First fine motion
Switch and the second microswitch are connected with the controller.
A kind of 5. two-in-one immunochromatographiassays assays instrument according to claim 1, it is characterised in that：The test strips base
Including chute, the chute is in same level with the test strips socket.
A kind of 6. two-in-one immunochromatographiassays assays instrument according to claim 1, it is characterised in that：The optical detecting module
Including for detecting the first detection module of collaurum and the second detection module for detecting fluorescence；The first detection module
Including the first light source and the first photodiode, second detection module includes secondary light source and the second photodiode.
A kind of 7. two-in-one immunochromatographiassays assays instrument according to claim 6, it is characterised in that：The controller respectively with
The first detection module and the connection of the second detection module.
A kind of 8. two-in-one immunochromatographiassays assays instrument according to claim 6, it is characterised in that：First light source is green
Radiant, the secondary light source are fluorescence excitation light source.
A kind of 9. two-in-one immunochromatographiassays assays instrument according to claim 6, it is characterised in that：The ripple of first light source
A length of 525nm.
A kind of 10. two-in-one immunochromatographiassays assays instrument according to claim 1, it is characterised in that：Testing agency's bag
Laser scanning light source is included, the laser scanning light source is connected to controller.
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| CN201720565616.2U CN206756843U (en) | 2017-05-21 | 2017-05-21 | A kind of two-in-one immunochromatographiassays assays instrument |
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| CN201720565616.2U CN206756843U (en) | 2017-05-21 | 2017-05-21 | A kind of two-in-one immunochromatographiassays assays instrument |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109085352A (en) * | 2018-09-26 | 2018-12-25 | 北京乐普医疗科技有限责任公司 | A kind of Optical devices of immunochromatographiassays assays instrument |
| CN109100341A (en) * | 2018-08-27 | 2018-12-28 | 绿嘉图（北京）科技有限公司 | A kind of multi-functional dry type POCT equipment and detection method |
| CN109444451A (en) * | 2018-12-27 | 2019-03-08 | 天津博硕科技有限公司 | A kind of automatic Tui Tiao mechanism |
| CN110161020A (en) * | 2019-04-30 | 2019-08-23 | 深圳市智城华业科技有限公司 | A kind of physical examination instrument |
| CN110220906A (en) * | 2019-06-28 | 2019-09-10 | 中国计量大学 | A kind of portable gold mark detector based on silicon photocell |
| CN110220895A (en) * | 2019-06-28 | 2019-09-10 | 中国计量大学 | A kind of image collecting device of high throughput portable colloidal gold CCD readout instrument |
| CN111795959A (en) * | 2020-07-24 | 2020-10-20 | 芯动森林(重庆)医疗科技有限公司 | Colloidal gold and fluorescence two-in-one data acquisition device and method |
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2017
- 2017-05-21 CN CN201720565616.2U patent/CN206756843U/en active Active
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109100341A (en) * | 2018-08-27 | 2018-12-28 | 绿嘉图（北京）科技有限公司 | A kind of multi-functional dry type POCT equipment and detection method |
| CN109085352A (en) * | 2018-09-26 | 2018-12-25 | 北京乐普医疗科技有限责任公司 | A kind of Optical devices of immunochromatographiassays assays instrument |
| CN109444451A (en) * | 2018-12-27 | 2019-03-08 | 天津博硕科技有限公司 | A kind of automatic Tui Tiao mechanism |
| CN110161020A (en) * | 2019-04-30 | 2019-08-23 | 深圳市智城华业科技有限公司 | A kind of physical examination instrument |
| CN110220906A (en) * | 2019-06-28 | 2019-09-10 | 中国计量大学 | A kind of portable gold mark detector based on silicon photocell |
| CN110220895A (en) * | 2019-06-28 | 2019-09-10 | 中国计量大学 | A kind of image collecting device of high throughput portable colloidal gold CCD readout instrument |
| CN111795959A (en) * | 2020-07-24 | 2020-10-20 | 芯动森林(重庆)医疗科技有限公司 | Colloidal gold and fluorescence two-in-one data acquisition device and method |
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