CN206443022U - A kind of device for casting of experimental animal - Google Patents
A kind of device for casting of experimental animal Download PDFInfo
- Publication number
- CN206443022U CN206443022U CN201720073354.8U CN201720073354U CN206443022U CN 206443022 U CN206443022 U CN 206443022U CN 201720073354 U CN201720073354 U CN 201720073354U CN 206443022 U CN206443022 U CN 206443022U
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- CN
- China
- Prior art keywords
- casting
- hermetic bag
- experimental animal
- catheter needle
- animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
The utility model discloses a kind of device for casting of experimental animal, the device for casting includes the hermetic bag (1) that upper end open is used to wrap up animal hearts, it is clipped in the clips (2) of hermetic bag upper end, it is arranged on the recovery tube (3) of hermetic bag (1) lower end, the perfusion liquid returnable bottle (4) being connected with recovery tube (3), and irrigator (5), irrigator (5) end is provided with catheter needle (6), catheter needle (6) is stretched into hermetic bag and is connected with hermetic bag sealing, the catheter needle (6) penetrates sustainer and the fixation of animal hearts left ventricle.The device for casting that the utility model is provided is simple in construction, can quickly reclaim perfusion liquid, it is to avoid it, which is evaporate into air, pollutes environment, and harm operating personnel are healthy.
Description
Technical field
The utility model belongs to experimental animal perfusion technique field, more particularly to a kind of device for casting of experimental animal.
Background technology
In the research of tissues of experimental animals pathological experiment, in situ hybridization and immunohistochemical study are particularly carried out, to keep away
Exempt from or reduce after death tissue morphology and structure changes, be usually used in before animal puts to death, using perfusion fixation.
Current numerous scientific research personnel when using perfusion fixation more than combined using syringe or infusion bottle with injection needle
Easy device is irrigated to perfusion liquid, and after perfusion platform use, many perfusion liquids are remained above, reclaims more numb
It is tired, it is even more important that perfusion liquid contains the toxicity liquid such as formaldehyde, high volatility, the perfusion liquid harm on perfusion platform of trickling
The health of experiment operator.
The Chinese patent of Application No. 201520295283.7 discloses a kind of animal perfusion platform, and it includes workbench, receipts
Collect container and suspension holdfast, the suspension holdfast is set on the table, and drain outlet is provided with below the workbench, described
It is provided with workbench and slips through the net and connect drain outlet, the drain outlet connects multiple collection vessels, each collect is held
Device porch is provided with valve.Animal perfusion platform is complicated, because the device for receiving perfusion liquid is connected with workbench, first
The toxic liquids such as aldehyde can still be volatilized, and endanger the health of operator.
Utility model content
In view of the shortcomings of the prior art, the utility model provides a kind of device for casting of experimental animal, the device for casting
The stronger perfusion liquid of toxicity can be reclaimed, it is simple in construction, it is easy to use.
The technical solution of the utility model is as follows：A kind of device for casting of experimental animal, the device for casting includes upper end
It is open for the hermetic bag 1 for wrapping up animal hearts, is clipped in the clips 2 of hermetic bag upper end, is arranged on the recovery of the lower end of hermetic bag 1
Pipe 3, the perfusion liquid returnable bottle 4 being connected with recovery tube 3, and irrigator 5, the end of irrigator 5 are provided with catheter needle 6, perfusion
Pin 6 is stretched into hermetic bag and is connected with hermetic bag sealing, and the catheter needle 6 is penetrated in the sustainer of animal hearts left ventricle and made
Fixed with clips 2.
Further, the irrigator 5 is syringe or the automatic injection pump of adjustable perfusion dynamics.
Further, the clips 2 are clipped in the upper end of hermetic bag 1 and heart aortic root inserts the portion of catheter needle
Point.
Set rubber blanket 11 to be used to seal in the hermetic bag 1, penetrated again by left ventricle after the insertion rubber blanket 11 of catheter needle 6
Sustainer.
Preferably, pressure is larger when irrigator is irrigated, and perfusion liquid flows out to sealing for sealing under normal circumstances in hermetic bag 1
After bag, perfusion liquid energy is flowed in returnable bottle along recovery tube, but to prevent that perfusion liquid outflow is not smooth when irrigating beginning, or
When hermetic bag air-tightness goes wrong, extraction valve 7 is provided with the top of the returnable bottle 4, for extracting the air in returnable bottle,
Negative pressure is formed, is easy to perfusion liquid smoothly to flow out.
Further, the recovery tube 3 is provided with flow regulator 8, for adjusting perfusion liquid outflow size, and extracts
Hermetic bag can be isolated with returnable bottle during returnable bottle air, it is ensured that perfusion liquid smoothly flows out when starting perfusion.
Further, the returnable bottle 4 is vial.
Further, the device for casting also includes operating desk 9.
Further, the operating desk 9 is provided with flush pipe 10, and the flush pipe 10 is fixed on one end of operating desk,
The other end can be connected on tap, be easy to perfusion to terminate post-flush operation platform.
Operation principle of the present utility model is as follows：The upper end open of hermetic bag 1 is used in the device for casting that the utility model is provided
In parcel animal hearts, clips 2 are clipped in hermetic bag upper end and heart sustainer upper end, and recovery tube 3 is arranged under hermetic bag 1
End, recovery tube 3 is connected with perfusion liquid returnable bottle 4, the end of irrigator 5 provided with catheter needle 6, catheter needle 6 stretch into hermetic bag it is interior and with
Hermetic bag is sealed and (can such as use rubber blanket), and catheter needle 6, which is penetrated in the sustainer of animal hearts left ventricle, to be used to irrigate,
The right auricle of heart of heart cuts mouth, and perfusion liquid is flowed in hermetic bag, the flow regulator 8 closed on recovery tube 3, isolation recovery tube with
Returnable bottle, then extracts the air in returnable bottle, is formed after negative pressure, open flow regulator 8, the perfusion liquid in hermetic bag along
Recovery tube is flowed in returnable bottle, completes to reclaim.
Compared with prior art, the utility model has the advantages that：The device for casting knot that the utility model is provided
Structure is simple, can quickly reclaim preservation perfusion liquid, be conducive to the recycling of perfusion liquid and focusing on for waste liquid, and avoid
It, which is evaporate into air, pollutes environment, and harm operating personnel are healthy.
Brief description of the drawings
The structural representation for the device for casting that Fig. 1 provides for the utility model；
Fig. 2 is the structural representation of operating desk；
Marked in figure：1- hermetic bags, 2- clips, 3- recovery tubes, 4- returnable bottles, 5- irrigators, 6- catheter needles, 7- pumpings
Valve, 8- flow regulators, 9- operating desks, 10- flush pipes, 11- rubber blankets.
Embodiment
The technical solution of the utility model is described in further details with specific embodiment below in conjunction with the accompanying drawings, but this reality
Following technical scheme is not limited to new.
Embodiment 1
As shown in figure 1, the device for casting includes hermetic bag 1, clips 2, recovery tube 3, returnable bottle 4, irrigator 5, filling
Pin 6, extraction valve 7 and flow regulator 8 are noted, wherein, the upper end open of hermetic bag 1 is used to wrap up animal hearts, and clips 2 are clipped in close
The upper end of envelope 1 and heart aortic root insert the part of catheter needle, and the lower end of hermetic bag 1 is used for provided with tube connection ports are reclaimed
Recovery tube 3 is connected, the other end of recovery tube 3 is connected with perfusion liquid returnable bottle 4, the end of irrigator 5 is provided with catheter needle 6, catheter needle 6 is stretched
Enter in hermetic bag 1 and be connected with the sealing of hermetic bag 1, to ensure sealing, the present embodiment sets rubber in the relevant position of hermetic bag 1
Sustainer is penetrated by left ventricle again after in rubber cushion 11, the insertion rubber blanket 11 of catheter needle 6.In order to distinguish each knot in figure in accompanying drawing
Structure, catheter needle 6 is longer, and the length of catheter needle, generally 5cm or so can be configured as needed in application.This implementation
Irrigator 5 is syringe in example.
Recovery tube 3 is provided with flow regulator 8, for adjusting perfusion liquid outflow size, and when extracting returnable bottle air
Hermetic bag can be isolated with returnable bottle, be easy to perfusate during perfusion beginning smoothly to flow out.
The top of returnable bottle 4 is additionally provided with extraction valve 7, for extracting the air in returnable bottle, forms negative pressure.The returnable bottle
4 be vial.
In addition, the device for casting also includes operating desk 9；Operating desk 9 is provided with flush pipe 10, and the flush pipe 10 is fixed
In one end of operating desk, the other end can be connected on tap, see Fig. 2.
The device for casting is as follows using process：Anatomy experiment animal (such as small white mouse or big white mouse), in the right heart of heart
Ear cuts a mouth, and the animal hearts that right auricle of heart is broken are in the hermetic bag 1 of connection retracting device, and catheter needle 6 first penetrates sealing
The catheter needle insertion rubber blanket of bag, then animal hearts sustainer is penetrated by left ventricle, clips 2 are clipped in hermetic bag upper end and the heart
Dirty aortic root inserts the part of catheter needle, and itself and hermetic bag and the aortic root for inserting catheter needle are fixed, opened back
Flow controller 8 in closed tube 3, injects emitter or automatic filling manually, and perfusion liquid is flowed in hermetic bag from right auricle of heart cut,
Then flow to and formed the perfusion liquid returnable bottle of negative pressure (another purpose of negative pressure is to prevent perfusion liquid steam air inlet
In).After perfusion terminates, to ensure that the perfusion liquid reclaimed will not be flowed backward in environment, the flow regulator 8 on closing recovery tube 3,
Isolate recovery tube and returnable bottle, perfusion liquid is flowed in returnable bottle along recovery tube, complete to reclaim.Hermetic bag, syringe and recovery
The disposable devices of Guan Kewei, cut off the part of insertion catheter needle from sustainer after the completion of perfusion, can make without opening closed folder
Obtain perfusion liquid free from environmental pollution to greatest extent.During due to perfusion, first reuse perfusion liquid using physiological saline lavation tissue and fill
Note, in order that the physiological saline reclaimed is separately disposed with perfusion liquid, can prepare multiple returnable bottles and replace.
The device for casting is applicable not only to the perfusion of meiofauna, is also applied for the perfusion of larger animal；Not only it is applicable
In from heart perfusion, the independent perfusion of other organs, e.g., liver are also applied for.
Claims (9)
1. a kind of device for casting of experimental animal, it is characterised in that the device for casting, which includes upper end open, to be used to wrap up animal
The hermetic bag (1) of heart, is clipped in the clips (2) of hermetic bag (1) upper end, is arranged on the recovery tube (3) of hermetic bag (1) lower end,
The perfusion liquid returnable bottle (4) being connected with recovery tube (3), and irrigator (5), irrigator (5) end are provided with catheter needle
(6), catheter needle (6) is stretched into hermetic bag and is connected with hermetic bag sealing, and catheter needle (6) penetrates the active of animal hearts left ventricle
Fixed after in arteries and veins using clips.
2. the device for casting of experimental animal as claimed in claim 1, it is characterised in that the clips (2) are clipped in hermetic bag
(1) upper end and heart aortic root insert the position of catheter needle.
3. the device for casting of experimental animal as claimed in claim 1, it is characterised in that the irrigator (5) be syringe or
The automatic injection pump of adjustable perfusion dynamics.
4. the device for casting of experimental animal as claimed in claim 1, it is characterised in that rubber is set on the hermetic bag (1)
Pad (11) is used to seal, and sustainer is penetrated by left ventricle again after catheter needle (6) insertion rubber blanket (11).
5. the device for casting of experimental animal as claimed in claim 1, it is characterised in that the top of the returnable bottle (4) is also set
There is extraction valve (7).
6. the device for casting of experimental animal as claimed in claim 1, it is characterised in that the recovery tube (3) is provided with flow
Adjuster (8).
7. the device for casting of experimental animal as claimed in claim 1, it is characterised in that the returnable bottle (4) is vial.
8. the device for casting of the experimental animal as described in claim 1~7 is any, it is characterised in that the device for casting is also wrapped
Include operating desk (9).
9. the device for casting of experimental animal as claimed in claim 8, it is characterised in that the operating desk (9) is provided with flushing
Manage (10), the flush pipe (10) is fixed on one end of operating desk, and the other end can be connected on tap.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720073354.8U CN206443022U (en) | 2017-01-19 | 2017-01-19 | A kind of device for casting of experimental animal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720073354.8U CN206443022U (en) | 2017-01-19 | 2017-01-19 | A kind of device for casting of experimental animal |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206443022U true CN206443022U (en) | 2017-08-29 |
Family
ID=59666777
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201720073354.8U Expired - Fee Related CN206443022U (en) | 2017-01-19 | 2017-01-19 | A kind of device for casting of experimental animal |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206443022U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108606854A (en) * | 2018-04-20 | 2018-10-02 | 中国水产科学研究院东海水产研究所 | A method of blood in the removal fish gill |
| CN111700062A (en) * | 2020-06-19 | 2020-09-25 | 山东中医药大学 | Intelligent rodent heart perfusion device |
| CN115979749A (en) * | 2022-12-06 | 2023-04-18 | 扬州市职业大学(扬州开放大学) | Perfusion fixing device for pathological section |
-
2017
- 2017-01-19 CN CN201720073354.8U patent/CN206443022U/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108606854A (en) * | 2018-04-20 | 2018-10-02 | 中国水产科学研究院东海水产研究所 | A method of blood in the removal fish gill |
| CN111700062A (en) * | 2020-06-19 | 2020-09-25 | 山东中医药大学 | Intelligent rodent heart perfusion device |
| CN115979749A (en) * | 2022-12-06 | 2023-04-18 | 扬州市职业大学(扬州开放大学) | Perfusion fixing device for pathological section |
| CN115979749B (en) * | 2022-12-06 | 2023-06-13 | 扬州市职业大学(扬州开放大学) | Perfusion fixing device for pathological section |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170829 Termination date: 20200119 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |