CN206298600U - A kind of circulating tumor cell capture agent box - Google Patents

A kind of circulating tumor cell capture agent box Download PDF

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Publication number
CN206298600U
CN206298600U CN201621421807.3U CN201621421807U CN206298600U CN 206298600 U CN206298600 U CN 206298600U CN 201621421807 U CN201621421807 U CN 201621421807U CN 206298600 U CN206298600 U CN 206298600U
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China
Prior art keywords
device groove
lid
rack
tumor cell
control panel
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CN201621421807.3U
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Chinese (zh)
Inventor
李鹏
张晓飞
王硕
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Xi'an Zhen Zhen Biological Medicine Technology Co Ltd
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Xi'an Zhen Zhen Biological Medicine Technology Co Ltd
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Abstract

The utility model discloses a kind of circulating tumor cell capture agent box,The side of box body is provided with lid,Snapped connection by first between box body and lid,The bottom of box body is provided with control panel,Aerial condenser and heater are provided with the top of control panel,Placement plate is provided with above aerial condenser and heater,Place and be provided with fixed plate above plate,Putting hole is provided with the middle part of fixed plate,Putting hole is built-in to be equipped with sample cup placement,First device groove and second device groove are provided with the inside of lid,Dividing plate is provided between first device groove and second device groove,Rack is additionally provided with the inside of lid,Shelf bottle is placed with rack,Temperature sensor is installed above rack,This kind of circulating tumor cell capture agent box,The temperature inside kit can be adjusted,So that blood storage or transport are in suitable temperature,It is easy to preferably preserve and operates,Using filter membrane,Ficoll and microchip are separated and captured to blood.

Description

A kind of circulating tumor cell capture agent box
Technical field
The utility model is related to a kind of kit, specially a kind of circulating tumor cell capture agent box.
Background technology
Circulating tumor cell (abbreviation CTC) refers to the cell that peripheral blood is shedded into from primary tumor tissue, with research Go deep into, CTC is increasingly becoming important tumor sample source, for clinic provides reference and guidance.But its quantity is more rare, Only 1-10 CTC in the every 10ml peripheral bloods of most patients, therefore fully excavate research and the clinical value not a duck soup of CTC. Need by know-how, could by CTC and other benign in patient body circulating cells (such as red blood cell, leucocyte) and on Chrotoplast is separated, and temperature in traditional CTC capture agent boxes is not suitable enough, causes blood to easily cause cold Freeze.
Accordingly, it would be desirable to design a kind of circulating tumor cell capture agent box to solve problems.
Utility model content
The purpose of this utility model is to provide a kind of circulating tumor cell capture agent box, to solve above-mentioned background technology The problem of middle proposition.
To achieve the above object, the utility model provides following technical scheme:A kind of circulating tumor cell capture agent box, Including box body, lid, the first buckle, control panel, aerial condenser, heater, place plate, through hole, fixed plate, putting hole, Sample cup placement, first device groove, second device groove, dividing plate, closure, the second buckle, rack, shelf bottle and TEMP Device, the side of the box body is provided with the lid, is snapped connection by described first between the box body and the lid, described The bottom of box body is provided with the control panel, and the aerial condenser and the heater are provided with the top of the control panel, The placement plate is provided with above the aerial condenser and the heater, it is described logical that the placement plate is provided with several Hole, is provided with the fixed plate above the placement plate, the putting hole is provided with the middle part of the fixed plate, in the putting hole Device has the sample cup placement, and the first device groove and the second device groove, described are provided with the inside of the lid It is provided with the dividing plate between one device groove and the second device groove, the side of the first device groove and the second device groove The closure is provided with, and is snapped connection by described second between the closure, institute is additionally provided with the inside of the lid Rack is stated, described device bottle is placed with the rack, the temperature sensor is installed above the rack.
Further, the built-in filter membrane for being equipped with micron of the first device groove, the second device groove is built-in be equipped with it is micro- Chip.
Further, it is fixedly connected between the temperature sensor and the inner side of the lid, and the temperature sensor The control panel is electrically connected with, the control panel is electrically connected with the aerial condenser and the heater.
Further, it is fixedly connected between the rack and the inner side of the lid.
Further, described device bottle is built-in is equipped with ficoll.
Compared with prior art, the beneficial effects of the utility model are:This kind of circulating tumor cell capture agent box, it is internal Aerial condenser and heater are provided with, the temperature inside kit can be adjusted so that blood storage or transport are in suitable temperature Degree, is easy to preferably preserve and operates, and blood is separated and captured using filter membrane, ficoll and microchip.
Brief description of the drawings
Fig. 1 is overall structure diagram of the present utility model;
Fig. 2 is that sample of the present utility model places board mounting structure schematic diagram;
In reference:1st, box body;2nd, lid;3rd, the first buckle;4th, control panel;5th, aerial condenser;6th, heater; 7th, plate is placed;8th, through hole;9th, fixed plate;10th, putting hole;11st, sample cup placement;12nd, first device groove;13rd, second device groove; 14th, dividing plate;15th, closure;16th, the second buckle;17th, rack;18th, shelf bottle;19th, temperature sensor.
Specific embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is carried out Clearly and completely describe, it is clear that described embodiment is only a part of embodiment of the utility model, rather than whole Embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not under the premise of creative work is made The every other embodiment for being obtained, belongs to the scope of the utility model protection.
Fig. 1-2 is referred to, the utility model provides a kind of technical scheme:A kind of circulating tumor cell capture agent box, bag Include box body 1, lid 2, the first buckle 3, control panel 4, aerial condenser 5, heater 6, place plate 7, through hole 8, fixed plate 9, Putting hole 10, sample cup placement 11, first device groove 12, second device groove 13, dividing plate 14, closure 15, the second buckle 16, put Frame 17, shelf bottle 18 and temperature sensor 19 are put, the side of box body 1 is provided with lid 2, by the first card between box body 1 and lid 2 Button 3 is connected, and the bottom of box body 1 is provided with control panel 4, and the top of control panel 4 is provided with aerial condenser 5 and heater 6, air Condenser 5 is provided with placement plate 7 with the top of heater 6, places plate 7 and is provided with several through holes 8, and the top for placing plate 7 is provided with Fixed plate 9, the middle part of fixed plate 9 is provided with putting hole 10, and putting hole 10 is built-in to be equipped with sample cup placement 11, and the inner side of lid 2 sets There are first device groove 12 and second device groove 13, dividing plate 14, the first dress are provided between first device groove 12 and second device groove 13 Put groove 12 and be provided with closure 15 with the side of second device groove 13, and be connected by the second buckle 16 between closure 15, box The inner side of lid 2 is additionally provided with rack 17, and shelf bottle 18 is placed with rack 17, and the top of rack 17 is provided with TEMP Device 19.
Further, the built-in filter membrane for being equipped with 8 micron pore sizes of first device groove 12, second device groove 13 is built-in be equipped with it is micro- Chip, filter membrane is used for the leucocyte in filtering blood.
Further, it is fixedly connected between temperature sensor 19 and the inner side of lid 2, and temperature sensor 19 is electrically connected with Control panel 4, control panel 4 is electrically connected with aerial condenser 5 and heater 6.
Further, it is fixedly connected between rack 17 and the inner side of lid 2, rack 17 is used for apparatus for placing bottle 18.
Further, shelf bottle 18 is built-in is equipped with ficoll, and ficoll is used for capturing CTC.
Operation principle:The side of this kind of kit 1 is provided with lid 2, and the first buckle 3 is passed through between box body 1 and lid 2 Connection, the bottom of box body 1 is provided with control panel 4, and the top of control panel 4 is provided with aerial condenser 5 and heater 6, and air is cold Condenser 5 is provided with placement plate 7 with the top of heater 6, places plate 7 and is provided with several through holes 8, and the top for placing plate 7 is provided with solid Fixed board 9, the middle part of fixed plate 9 is provided with putting hole 10, and built-in being equipped with of putting hole 10 can in sample cup placement 11, sample cup placement 11 Blood sample is placed, the inner side of lid 2 is provided with first device groove 12 and second device groove 13, first device groove 12 and second device It is provided with dividing plate 14 between groove 13, the built-in filter membrane for being equipped with 8 micron pore sizes of first device groove 12, second device groove 13 is built-in to be equipped with Microchip, first device groove 12 is provided with closure 15 with the side of second device groove 13, and passes through second between closure 15 Buckle 16 is connected, and the inner side of lid 2 is additionally provided with rack 17, and shelf bottle 18, the top of rack 17 are placed with rack 17 Temperature sensor 19 is installed, because blood needs suitable temperature in storage and transport, therefore, temperature sensor 19 can be felt The temperature in kit is answered, if the temperature in kit is too low, information will be transmitted to control panel 4 by temperature sensor 19, Control panel 4 will control heater 6 to begin to warm up, if the temperature in kit is too high, will control panel 4 will control Aerial condenser 5 starts condensation, and the temperature in kit is lowered the temperature, in specific separation and capture CTC, first with 8 The filter membrane of micron pore size filters out the leucocyte in blood, using ficoll by the list in CTC and red blood cell and blood plasma Nucleus is separated, and because CTC is higher relative to the volume and non-deformability of other cells in blood, finally can use microchip Capture CTC.
While there has been shown and described that embodiment of the present utility model, for the ordinary skill in the art, It is appreciated that these embodiments can be carried out various changes in the case where principle of the present utility model and spirit is not departed from, repaiies Change, replace and modification, scope of the present utility model is defined by the appended claims and the equivalents thereof.

Claims (5)

1. a kind of circulating tumor cell capture agent box, including box body (1), lid (2), the first buckle (3), control panel (4), Aerial condenser (5), heater (6), placement plate (7), through hole (8), fixed plate (9), putting hole (10), sample cup placement (11), first device groove (12), second device groove (13), dividing plate (14), closure (15), the second buckle (16), rack (17), shelf bottle (18) and temperature sensor (19), it is characterised in that:The side of the box body (1) is provided with the lid (2), It is connected by first buckle (3) between the box body (1) and the lid (2), the bottom of the box body (1) is provided with described Control panel (4), is provided with the aerial condenser (5) and the heater (6), the sky at the top of the control panel (4) Placement plate (7) is provided with above gas condenser (5) and the heater (6), placement plate (7) is provided with several institutes Through hole (8) is stated, the fixed plate (9) is provided with above placement plate (7), described putting is provided with the middle part of the fixed plate (9) Hole (10) is put, the putting hole (10) is built-in to be equipped with the sample cup placement (11), described is provided with the inside of the lid (2) One device groove (12) and the second device groove (13), set between the first device groove (12) and the second device groove (13) There is the dividing plate (14), the first device groove (12) is provided with the closure with the side of the second device groove (13) (15), and between the closure (15) it is connected by second buckle (16), institute is additionally provided with the inside of the lid (2) Rack (17) is stated, described device bottle (18) is placed with the rack (17), be provided with above the rack (17) The temperature sensor (19).
2. a kind of circulating tumor cell capture agent box according to claim 1, it is characterised in that:The first device groove (12) the built-in filter membrane for being equipped with 8 micron pore sizes, the second device groove (13) is built-in to be equipped with microchip.
3. a kind of circulating tumor cell capture agent box according to claim 1, it is characterised in that:The temperature sensor (19) it is fixedly connected between the inner side of the lid (2), and the temperature sensor (19) is electrically connected with the control panel (4), the control panel (4) is electrically connected with the aerial condenser (5) and the heater (6).
4. a kind of circulating tumor cell capture agent box according to claim 1, it is characterised in that:The rack (17) It is fixedly connected between the inner side of the lid (2).
5. a kind of circulating tumor cell capture agent box according to claim 1, it is characterised in that:Described device bottle (18) It is built-in to be equipped with ficoll.
CN201621421807.3U 2016-12-23 2016-12-23 A kind of circulating tumor cell capture agent box Active CN206298600U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201621421807.3U CN206298600U (en) 2016-12-23 2016-12-23 A kind of circulating tumor cell capture agent box

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201621421807.3U CN206298600U (en) 2016-12-23 2016-12-23 A kind of circulating tumor cell capture agent box

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CN206298600U true CN206298600U (en) 2017-07-04

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108020437A (en) * 2017-12-12 2018-05-11 山东省肿瘤防治研究院 A kind of tumour sampling equipment easy to preservation classification
CN110142068A (en) * 2019-06-12 2019-08-20 杭州华得森生物技术有限公司 A kind of Epithelial and stromal mixed type circulating tumor cell detection kit and method
CN112630453A (en) * 2020-12-23 2021-04-09 贵州金域医学检验中心有限公司 Constant temperature kit for gynecological tumor marker detection and detection method thereof
CN114873073A (en) * 2021-10-28 2022-08-09 江苏艾洛特医药研究院有限公司 Circulating tumor cell capture kit
CN115201476A (en) * 2022-09-15 2022-10-18 长沙普方德医疗器械有限公司 Circulating tumor cell detection equipment and use method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108020437A (en) * 2017-12-12 2018-05-11 山东省肿瘤防治研究院 A kind of tumour sampling equipment easy to preservation classification
CN110142068A (en) * 2019-06-12 2019-08-20 杭州华得森生物技术有限公司 A kind of Epithelial and stromal mixed type circulating tumor cell detection kit and method
CN110142068B (en) * 2019-06-12 2024-02-02 杭州华得森生物技术有限公司 Kit and method for detecting epithelial and mesenchymal mixed circulating tumor cells
CN112630453A (en) * 2020-12-23 2021-04-09 贵州金域医学检验中心有限公司 Constant temperature kit for gynecological tumor marker detection and detection method thereof
CN114873073A (en) * 2021-10-28 2022-08-09 江苏艾洛特医药研究院有限公司 Circulating tumor cell capture kit
CN115201476A (en) * 2022-09-15 2022-10-18 长沙普方德医疗器械有限公司 Circulating tumor cell detection equipment and use method thereof

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