CN206145189U - Multi -functional chromatogram diverter valve - Google Patents
Multi -functional chromatogram diverter valve Download PDFInfo
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- CN206145189U CN206145189U CN201621158266.XU CN201621158266U CN206145189U CN 206145189 U CN206145189 U CN 206145189U CN 201621158266 U CN201621158266 U CN 201621158266U CN 206145189 U CN206145189 U CN 206145189U
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- hole
- switching valve
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Abstract
The utility model aims at providing a multi -functional chromatogram diverter valve comprises valve body (I) and rotation motor (II), valve body (I) constitute by stator (III) and rotor (IV), last rotor (VII) fix on rotor housing (XI) through bearing (X), again with rotate motor (II) and link to each other through shaft joint (XII), rotate motor (II) and drive that to rotate upward son (VII) rotatory when rotatory to drive rotor (VIII) and rotor route (IX) rotation down. Outstanding effect is: (1 )Make chromatographic fractionation new technologies such as the column choice switches, online enrichment, two -dimensional separation, simulation removal bed change in the realization. (2 ) simple structure has, the characteristics of easily production processing, and the production and processing is with low costs. (3 )The valve body dead volume is little, and more kind of valves closes the use and can gain higher separation effect. (4 )The range of application is wide.
Description
Technical field
This utility model is related to a kind of multi-functional chromatograph switching valve and its method for chromatographic isolation, more specifically,
It is related to a kind of switching by stream and realizes the switching valve of various chromatograph clastotypes, belongs to instrument, equipment technical field.
Background technology
Chromatography is a kind of separation and analysis method, is had very in fields such as analytical chemistry, organic chemistry, biochemistrys
It is widely applied, is the most rapid research field of most widely used development in analytical chemistry, new technologies emerges in an endless stream.
High performance liquid chromatography is the most commonly used chromatographic process, organic chemistry, biochemistry, medical science, drug development with
The aspects such as detection, chemical industry, Food Science, environmental monitoring, commodity inspection and method inspection are all widely used.And for the sample of complicated component
Product, analysis requires higher, needs to use new technologies and methods and combines and could realize separating analysis purpose, and the selection of example post switches skill
Art, on-line concentration, two dimensional separation technology, simulated moving bed technology etc., are required to carry out fluid stream in these new techniques
Road switches.When fluid flowing path switching is carried out, it is to combine to realize using various different switching valves under normal circumstances, stream
Design is complicated, and control is difficult, and the delayed volume of system is larger.
The content of the invention
The purpose of this utility model is to overcome the deficiencies in the prior art, there is provided a kind of to be realized various by stream switching
The multi-functional chromatograph switching valve of chromatographic isolation pattern, makes various chromatograph separation technologies such as post select handoff technique, on-line preconcentration
Technology, two dimensional separation technology, simulated moving bed technology are more easily implemented.
The purpose of this utility model is achieved through the following technical solutions：
A kind of multi-functional chromatograph switching valve, by valve body（I）And rotary electric machine（II）Composition；Described valve body（I）By stator
（III）And rotor（IV）Composition；Described stator（III）Center be provided with through hole, it is different in 3 with central through hole as the center of circle
It is equidistant on the circle of radius to be provided with equal number of through hole；Stator（III）With rotor（IV）The one end being connected is provided with stator
Sealing（V）, the other end is fluid inlet and outlet（VI）, it is connected with respective line；Described seal stator（V）On be provided with quantity and position
Put and stator（III）The through hole for matching completely；Described rotor（IV）By upper rotor part（VII）, lower rotor part（VIII）And rotor
Path（IX）Composition, rotor path（IX）It is fixed on lower rotor part（VIII）On, upper rotor part（VII）And lower rotor part（VIII）Between fill
There is high pressure spring（T）；Described upper rotor part（VII）By bearing（X）It is fixed on rotor case（XI）On, then with rotary electric machine
（II）By shaft joint（XII）It is connected, rotary electric machine（II）Upper rotor part is driven during rotation（VII）Rotation, so as to drive lower rotor part
（VIII）And rotor path（IX）Rotation.
Multi-functional chromatograph switching valve as elucidated before, preferred scheme is, the seal stator（V）, rotor path
（IX）For PEEK materials.
Multi-functional chromatograph switching valve as elucidated before, preferred scheme is, the upper rotor part（VII）, lower rotor part
（VIII）, stator（III）For rustless steel or PEEK materials.
This utility model additionally provides the application of described multi-functional chromatograph switching valve, is to be applied to select to switch in terminal
Chromatographic isolation, be applied to on-line preconcentration chromatographic isolation or be applied to comprehensive two dimensional gas chromatography separation.
It is described be applied to terminal select switching chromatograph separate be：By mobile phase M, chromatogram pump P, injection valve V this stream
With the centre bore of multi-functional chromatograph switching valve（0）It is connected, in the first circle of multi-functional chromatograph switching valve（From inside to outside）It is logical
Connect the entrance point of different chromatographic columns on the hole of road respectively, the port of export of chromatographic column is connected to corresponding 3rd circle（From introversion
Outward）Via hole on, the second circle of multi-functional chromatograph switching valve（From inside to outside）Via hole connected together with many logical, then
It is connected with detector D, the outflow end of detector D is connected with fraction collector F；During use, mobile phase M is in chromatogram pump P
Conveying under enter the centre bore of multi-functional chromatograph switching valve through injection valve V streams, terminal choosing may be implemented in by rotating transfer valve
Select switching chromatograph separation.
The on-line preconcentration chromatographic isolation that is applied to is：Mobile phase M, this stream of chromatogram pump P1 are cut with multi-functional chromatograph
No. 1 via hole for changing valve is connected, the centre bore of the entrance point of chromatographic column and multi-functional chromatograph switching valve（0）Be connected, the port of export with
Detector D connects, and the outlet of detector D is connected with receiving flask F, and the outlet of sample pump P2 is connected to multi-functional chromatograph switching valve
Second circle（From inside to outside）Via hole（10）On, one end of on-line preconcentration post Fj is connected to the of multi-functional chromatograph switching valve
One circle（From inside to outside）Via hole（2）On, the other end is connected to the second circle of multi-functional chromatograph switching valve（From introversion
Outward）Via hole（9）On, with threeway by the 3rd circle of multi-functional chromatograph switching valve（From inside to outside）No. 17 via holes and 18
The connection of number via hole, another path of threeway are connected to liquid waste collector W, be may be implemented in by multifunctional rotary chromatograph switching valve
Line is enriched with and detached conversion；Stream during enrichment is：The through hole of through hole → multifunction valve 2 of S → P2 → multifunction valve 10 →
The on-line preconcentration post Fj → through hole → W of through hole → multifunction valve 17 of multifunction valve 9, No. 1 through hole of M → P1 → multifunction valve → many
No. 0 through hole → chromatographic column C of duty valve → detector D → receiving flask F；Stream during separation is：S → P2 → multifunction valve 10 leads to
No. 18 through hole → W of hole → multifunction valve, the through hole of through hole → multifunction valve 9 of M → P1 → multifunction valve 1 → on-line preconcentration post Fj
Through hole → chromatographic column C of through hole → multifunction valve 0 of → multifunction valve 2 → detector D → receiving flask F.
It is described be applied to comprehensive two dimensional gas chromatography separate be：By mobile phase M1, chromatogram pump P1, injection valve V, chromatographic column C1, this is first-class
The centre bore of road and multi-functional chromatograph switching valve（0）It is connected, in the first circle of multi-functional chromatograph switching valve（From inside to outside）'s
Connect the entrance point of each chromatographic column on via hole respectively, the port of export of each chromatographic column is all connected on detector D, detector
The outflow end of D is connected with fraction collector F, the second circle of multi-functional chromatograph switching valve（From inside to outside）Via hole with leading to more
Connect together, then be connected with high-pressure pump P2 outlets, high-pressure pump P2 imports connection mobile phase M2；During use, mobile phase
M1 enters chromatographic column C1 through injection valve V streams under the conveying of chromatogram pump P1 carries out one-dimensional chromatographic isolation, and effluent stream enters multi-functional
The centre bore of chromatograph switching valve（0）, chromatographic column C1 outflow fraction is sequentially switched completely by multifunctional rotary chromatograph switching valve
To the first circle for being connected to function chromatograph switching valve（From inside to outside）Via hole on chromatographic column carry out two dimensional separation, so as to
Realize that the comprehensive two dimensional gas chromatography of complex sample is separated.
A kind of multi-functional chromatograph switching valve of this utility model and its prominent effect for the method for chromatographic isolation are：
(1) a kind of multi-functional chromatograph switching valve that this utility model is provided can be used for various chromatograph separation technologies so that
Post selects switching, on-line preconcentration, two dimensional separation, Simulation moving bed isochromatic spectrum separation technology to be more easily implemented.
(2) a kind of multi-functional chromatograph switching valve that this utility model is provided has simple structure, it is easy to the spy of production and processing
Point, production and processing low cost.
(3) a kind of multi-functional chromatograph switch valve structure that this utility model is provided is compact, and valve body dead volume is little, more various
Valve is applied in combination and can obtain higher separating effect.
(4) this utility model applied range, can be applicable to the various fields such as chemistry, chemical industry, petrochemical industry, medicine and food
The separation of complex sample, can be applicable to the separation of analytical type, preparative liquid chromatography and supercritical liq chromatograph.
Description of the drawings
Fig. 1 is multi-functional chromatograph switching valve schematic diagram；
Fig. 2 is valve body（I）Structural representation；
Fig. 3 is stator（III）Schematic diagram；
Fig. 4 is seal stator（V）Schematic diagram；
Fig. 5 is rotor path（IX）Schematic diagram；
Fig. 6 is that this utility model embodiment 1 selects switching chromatograph separation flow path schematic diagram in terminal；
Fig. 7 is 2 on-line preconcentration chromatographic isolation stream schematic diagram of this utility model embodiment；
3 comprehensive two dimensional gas chromatography separation flow path schematic diagram of Fig. 8 this utility model embodiment.
Specific embodiment
The concrete reality of a kind of multi-functional chromatograph switching valve of this utility model presented below and its method for chromatographic isolation
Apply mode.
Embodiment l
Accompanying drawing 1-5, a kind of multi-functional chromatograph switching valve and its method for chromatographic isolation are referred to, multi-functional chromatograph is cut
Valve is changed by valve body（I）, rotary electric machine（II）Composition, valve body（I）By stator（III）And rotor（IV）Composition, stator（III）In
The heart is provided with 1 through hole, equidistant on the circle of 3 different radiis with central through hole as the center of circle to be provided with 8 through holes；Stator
（III）With rotor（IV）The one end being connected is provided with seal stator（V）, the other end is fluid inlet and outlet（VI）, with respective tube
Road connects；Seal stator（V）On be provided with quantity and position and stator（III）The through hole for matching completely.Rotor（IV）By upper turn
Son（VII）, lower rotor part（VIII）And rotor path（IX）Composition, rotor path（IX）It is fixed on lower rotor part（VIII）On, it is upper to turn
Son（VII）Lower rotor part is driven during rotation（VIII）And rotor path（IX）Rotation, upper rotor part（VII）And lower rotor part（VIII）Between
Equipped with high pressure spring（T）, with rotor path（IX）And seal stator（V）Between produce pressure, be allowed to good seal.Rotor leads to
Road（IX）On be provided with and seal stator（V）The corresponding groove of upper through hole, playing makes stator（III）Inside and outside round tube hole connection or disconnected
The effect opened.Rotor（VII）By bearing（X）It is fixed on rotor case（XI）On, then with rotary electric machine（II）By shaft joint
（XII）It is connected, rotary electric machine（II）Upper rotor part is driven during rotation（VII）Rotation, so as to drive lower rotor part（VIII）It is logical with rotor
Road（IX）Rotation, so as to realize stream connection conversion.
Above-mentioned multi-functional chromatograph switching valve is applied to select switching chromatograph to separate in terminal, stream connection design is referred to
Accompanying drawing 6.By mobile phase M, chromatogram pump P, this stream of injection valve V and multi-functional chromatograph switching valve centre bore（0）It is connected, many
Connect the entrance point of different chromatographic columns, the port of export of C1-C8 chromatographic columns on the 1-8 via holes of function chromatograph switching valve respectively
On the via hole of the 17-24 for being connected respectively to multi-functional chromatograph switching valve, the via hole of the 9-16 of multi-functional chromatograph switching valve is used
It is more logical to connect together, then be connected with detector D, the outflow end of detector D is connected with fraction collector F.During use,
Mobile phase M enters the centre bore of multi-functional chromatograph switching valve under the conveying of chromatogram pump P through injection valve V streams, by rotating switching
Valve may be implemented in terminal and select switching chromatograph to separate, and selection is separated using C1-C8 chromatographic columns.
Embodiment 2
The multi-functional chromatograph switching valve of embodiment 1 is applied to into on-line preconcentration chromatographic isolation, stream connection design is referred to
Fig. 7.Mobile phase M, this stream of chromatogram pump P1 are connected with No. 1 via hole of multi-functional chromatograph switching valve, the import of chromatographic column
Hold the centre bore with multi-functional chromatograph switching valve（0）It is connected, the port of export is connected with detector D, the outlet of detector D and receiving flask
F connects, and the outlet of sample pump P2 is connected to the second circle of multi-functional chromatograph switching valve（From inside to outside）Via hole（10）On,
One end of on-line preconcentration post Fj is connected to the first circle of multi-functional chromatograph switching valve（From inside to outside）Via hole（2）On, separately
One end is connected to the second circle of multi-functional chromatograph switching valve（From inside to outside）Via hole（9）On, with threeway by multifunctional color
3rd circle of spectrum switching valve（From inside to outside）No. 17 via holes and the connection of No. 18 via holes, another path of threeway is connected to
Liquid waste collector W, is capable of achieving on-line preconcentration and detached conversion by multifunctional rotary chromatograph switching valve.Stream during enrichment
For：The through hole of through hole → multifunction valve 2 of S → P2 → multifunction valve 10 → on-line preconcentration post Fj → through hole of multifunction valve 9 →
No. 17 through hole → W of multifunction valve, through hole → chromatographic column C of through hole → multifunction valve 0 of M → P1 → multifunction valve 1 → detector D
→ receiving flask F.Stream during separation is：Through hole → the W of through hole → multifunction valve 18 of S → P2 → multifunction valve 10, M → P1 →
The through hole of through hole → multifunction valve 9 of the multifunction valve 1 → on-line preconcentration post Fj → through hole → multifunction valve 0 of multifunction valve 2
Through hole → chromatographic column C → detector D → receiving flask F.
Embodiment 3
The multi-functional chromatograph switching valve of embodiment 1 is applied to into comprehensive two dimensional gas chromatography separation, stream connection design refers to figure
8.By mobile phase M1, chromatogram pump P1, injection valve V, this stream of chromatographic column C1 and multi-functional chromatograph switching valve centre bore（0）Phase
Even, the entrance point of C2-1-C2-8 chromatographic columns, each color are connected on the 1-8 via holes of multi-functional chromatograph switching valve respectively
The port of export of spectrum post is connected respectively on a detector D, and the outflow end of detector D is connected with fraction collector F, multifunctional color
The 9-16 via holes of spectrum switching valve are connected together with more logical, then are connected with high-pressure pump P2 outlets, and high-pressure pump P2 imports connect
Connect mobile phase M2.During use, mobile phase M1 enters chromatographic column C1 through injection valve V streams under the conveying of chromatogram pump P1 carries out one
Dimension chromatographic isolation, effluent stream enter the centre bore of multi-functional chromatograph switching valve（0）, by multifunctional rotary chromatograph switching valve by color
Spectrum post C1 outflow fractions are sequentially switched to the chromatographic column being connected on the 1-8 via holes of function chromatograph switching valve completely carries out two
Dimension is separated, and two dimensional separation effluent is detected by each detector D, so as to the comprehensive two dimensional gas chromatography for realizing complex sample is separated.
The above is only preferred implementation of the present utility model, it is noted that for the common skill of the art
Art personnel, without departing from the concept of the premise utility, can also make some improvements and modifications, these improvements and modifications
Also should be regarded as in protection domain of the present utility model.
It is of the present utility model to complete to have benefited from grant of national natural science foundation（Project approval number：21675071）.
Claims (3)
1. a kind of multi-functional chromatograph switching valve, is characterized in that, by valve body（I）And rotary electric machine（II）Composition；Described valve body（I）
By stator（III）And rotor（IV）Composition；Described stator（III）Center be provided with through hole, in 3 with central through hole as the center of circle
It is equidistant on the circle of individual different radii to be provided with equal number of through hole；Stator（III）With rotor（IV）Install the one end being connected
There is seal stator（V）, the other end is fluid inlet and outlet（VI）, it is connected with respective line；Described seal stator（V）On be provided with number
Amount and position and stator（III）The through hole for matching completely；Described rotor（IV）By upper rotor part（VII）, lower rotor part（VIII）
And rotor path（IX）Composition, rotor path（IX）It is fixed on lower rotor part（VIII）On, upper rotor part（VII）And lower rotor part（VIII）
Between be equipped with high pressure spring（T）；Described upper rotor part（VII）By bearing（X）It is fixed on rotor case（XI）On, then with rotation
Motor（II）By shaft joint（XII）It is connected, rotary electric machine（II）Upper rotor part is driven during rotation（VII）Rotation, so as to drive down
Rotor（VIII）And rotor path（IX）Rotation.
2. multi-functional chromatograph switching valve as claimed in claim 1, is characterized in that, the seal stator（V）, rotor path（IX）
For PEEK materials.
3. multi-functional chromatograph switching valve as claimed in claim 1, is characterized in that, the upper rotor part（VII）, lower rotor part
（VIII）, stator（III）For rustless steel or PEEK materials.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621158266.XU CN206145189U (en) | 2016-11-01 | 2016-11-01 | Multi -functional chromatogram diverter valve |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201621158266.XU CN206145189U (en) | 2016-11-01 | 2016-11-01 | Multi -functional chromatogram diverter valve |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN206145189U true CN206145189U (en) | 2017-05-03 |
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ID=58623388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201621158266.XU Expired - Fee Related CN206145189U (en) | 2016-11-01 | 2016-11-01 | Multi -functional chromatogram diverter valve |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN206145189U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106321896A (en) * | 2016-11-01 | 2017-01-11 | 聊城大学 | Multifunctional chromatography switching valve and application thereof |
-
2016
- 2016-11-01 CN CN201621158266.XU patent/CN206145189U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106321896A (en) * | 2016-11-01 | 2017-01-11 | 聊城大学 | Multifunctional chromatography switching valve and application thereof |
| CN106321896B (en) * | 2016-11-01 | 2018-12-04 | 聊城大学 | A kind of multi-functional chromatography switching valve and its application |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170503 Termination date: 20201101 |