CN205844341U - A kind of full-automatic illumination immunity analysis instrument - Google Patents

A kind of full-automatic illumination immunity analysis instrument Download PDF

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Publication number
CN205844341U
CN205844341U CN201620707276.8U CN201620707276U CN205844341U CN 205844341 U CN205844341 U CN 205844341U CN 201620707276 U CN201620707276 U CN 201620707276U CN 205844341 U CN205844341 U CN 205844341U
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China
Prior art keywords
reagent
reaction
sample
plate
pin
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CN201620707276.8U
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Chinese (zh)
Inventor
黄鹤
张海峰
顾国庆
张延军
石学园
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JIAXING QUEST LIFE SCIENCE CO Ltd
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JIAXING QUEST LIFE SCIENCE CO Ltd
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Abstract

This utility model relates to technical field of medical equipment, specifically a kind of full-automatic illumination immunity analysis instrument.This full-automatic illumination immunity analysis instrument includes shell, support body, sample introduction frame, reaction cup storehouse, reaction tray, reagent disc, sample-adding module, reagent adding module, liquid circuit module, detection module and control module, described reaction cup storehouse, reaction tray, reagent disc, sample-adding module, reagent adding module is all located on support body, described shell is covered in outside described support body, described reaction tray includes the first reaction tray and the second reaction tray, described first reaction tray side is positioned at below described reaction cup storehouse, described reaction tray, reagent disc, sample-adding module is all connected with liquid circuit module with reagent adding module, described sample introduction frame, reaction cup storehouse, reaction tray, reagent disc, sample-adding module, reagent adding module, liquid circuit module, detection module all electrically connects with control module, described sample-adding module is connected with liquid circuit module with reagent adding module.

Description

A kind of full-automatic illumination immunity analysis instrument
Technical field
This utility model relates to technical field of medical equipment, specifically a kind of full-automatic illumination immunity analysis instrument.
Background technology
The supporting reagent of full-automatic illumination immunity analysis instrument is enzyme-catalyzed chemical luminescence method reagent, refers to known antibodies bag By in micropore reaction cup, add sample to be tested and ELIAS secondary antibody, carry out immunoreation, be eventually adding substrate, produce aura, A kind of technology of detected instrument capture.Full-automatic illumination immunity analysis instrument is used for analyzing in serum, blood plasma and other people body body fluid Analyte, quantitative patients serum and horseradish peroxidase join solid-phase coating to be had in the micropore cup of antibody, in serum Testing molecule be combined with the antibody specificity on the conjugate and solid phase carrier of horseradish peroxidase.Separating, washing unreacted Free composition.Then, adding luminol Luminol luminous substrate, the free energy utilizing chemical reaction to discharge excites centre Body, returns to excited state from ground state, and energy discharges with the form of photon, now, photon counter reads the photon of each micropore cup Number, the mathematical model that the testing molecule concentration in sample is set up according to standard substance carries out quantitative analysis.
Utility model content
This utility model provides a kind of simple in construction, that cross-contamination is few, Detection accuracy is high, detection efficiency is high is full-automatic Luminescence immunoassay instrument.
This utility model is achieved through the following technical solutions:
A kind of full-automatic illumination immunity analysis instrument, including shell, support body, sample introduction frame, reaction cup storehouse, reaction tray, reagent disc, Sample-adding module, reagent adding module, liquid circuit module, detection module and control module, described reaction cup storehouse, reaction tray, reagent disc, add Original mold block, reagent adding module are all located on support body, and described shell is covered in outside described support body, and described reaction tray includes that first is anti- Should coil and the second reaction tray, described first reaction tray side is positioned at below described reaction cup storehouse, described reaction tray, reagent disc, adds Original mold block is all connected with liquid circuit module with reagent adding module, described sample introduction frame, reaction cup storehouse, reaction tray, reagent disc, adds original mold Block, reagent adding module, liquid circuit module, detection module all electrically connect with control module.
Described reaction cup storehouse includes double-pole device, the first base plate, first fixes axle, the first motor, reaction cup pipe, reaction Cup, reaction top rotary table and reaction lower rotary table, described first lower end fixing axle is fixed on described first base plate, in described reaction Rotating disk and reaction lower rotary table are set with in the described first top and bottom fixing axle, and fill at the first motor and the first belt wheel Around the first solid fixed-axis rotation under the drive put, described reaction cup superposition is located at inside reaction cup pipe, the upper end of described reaction cup pipe Being installed on respectively on reaction top rotary table and reaction lower rotary table with lower end, described double-pole device is fixed on described by support means On first base plate, double-pole device is positioned at above described reaction top rotary table, and is positioned at directly over reaction cup pipe.
Described double-pole device include two double-pole motors, two screw mandrels, double-pole bearing, two double-pole guide rails and Two pieces of double-pole slide blocks, described support means includes that support and gripper shoe, described gripper shoe are fixed on described first by support On base plate, described double-pole bearing and two double-pole motors are parallel to each other on the surface being fixed on described gripper shoe, and two double Lifter guide is vertical and parallel is fixed on double-pole bearing, two pieces of double-pole slide blocks respectively with two double-pole slide Connecting, two screw mandrel lower ends are connected with two double-pole motor helical respectively, and upper end is connected with two pieces of double-pole slide blocks respectively.
Described reaction cup pipe includes two cavitys being parallel to each other, and two cavitys, reaction cup pipe are put in reaction cup superposition Lower end be provided with shell fragment around two cavitys.
The neighboring of described reaction top rotary table is provided with a circle reaction cup pipe clamp groove, is provided with anti-in each reaction cup pipe clamp groove Pipe clamping pieces, described reaction lower rotary table is answered to be provided with the through hole that a circle is corresponding with described reaction cup pipe clamp groove, the number of described through hole Amount is the twice of reaction cup pipe clamp groove, two through holes for a reaction cup pipe clamp groove, the upper end of reaction cup pipe snap in described instead In answering pipe clamping pieces, lower end is inserted in two through holes.
Described first fixes axle outer cover is provided with the first axle sleeve, and described first axle sleeve and first is fixed and is provided with two between axle Clutch shaft bearing, described first pulley arrangement includes the first big belt wheel, the first small pulley and the first belt, and described first small pulley is solid On the outfan of described first motor, the described first big belt wheel is installed on the lower end of described first axle sleeve, by the first skin First big belt wheel and the first small pulley are connected by band.
Described first reaction tray and the second reaction tray are mounted on reaction tray mounting base, and described first reaction tray includes First disk body, the first disk cover, the first rotating disk and the first driving device, described first rotating disk is located in the first disk body, the first disk cover Being covered in the first disk body top, and be positioned at above the first rotating disk, the first rotating disk rotates under the drive of the first driving device;Second Reaction tray includes that the second disk body, the second disk cover, the second rotating disk and the second driving device, described second rotating disk are located at the second disk body In, the second disk cover is covered in the second disk body top, and is positioned at above the second rotating disk, and the second rotating disk is in the drive of the second driving device Lower rotation.
In described first reaction tray, side is positioned at below reaction cup storehouse, and the reaction cup in described reaction cup storehouse is loaded into downwards On first rotating disk, described first disk cover being positioned at place below reaction warehouse and is provided with arc notch, described first disk cover is provided with first Reagent adding hole, reagent dilutions hole, well and sample-adding dilution holes.
Described second reaction tray is provided with the first cleaning device and second and cleans device, and described second disk cover is provided with first Washing plate hole and second and wash plate hole, described first cleans device includes that first washes plate module, the first lifting module and the first stop machine Structure, described first washes plate module is located at the first lifting module top, and is positioned at first and washes above plate hole, described first blocking mechanism It is located at first and washes plate module side;Described second clean device include the second cleaning module and second lifting module, described second Cleaning module is located at the second lifting module top, and is positioned at second and washes above plate hole;Described first blocking mechanism includes that first is fixed Position base plate, some first direct current generators, some first guide shafts and some first link gears, described first guide shaft one end is by the One guide shaft support is set in parallel on described first positioning plate upper surface, and the other end and the first link gear are connected, described The outfan of the first direct current generator is connected with described first link gear, and then drives the first guide shaft along the first guide shaft support Linear motion.
Described first link gear includes that head rod and the first cam, described first cam are located at described first direct current The outfan of motor, one end of described head rod is connected with the first cam rotation, and the other end rotates with described first guide shaft Connect, and fixed diametrically by guide shaft alignment pin.
The lower end of described guide shaft alignment pin is provided with sensing catch, relative with described sensing catch on described first positioning plate The position answered is provided with optocoupler sensor.
It is additionally provided with PMT light-metering assembly in described second reaction tray, is positioned at below described second reaction tray and just to described PMT light-metering assembly is provided with push rod component, and described push rod component includes that push rod base plate, DC stepper motor, push rod and push rod slide Mechanism, described DC stepper motor is located on described push rod base plate lower surface, and the outfan of DC stepper motor is provided with Push rod leading screw, described push rod is located at the upper end of described push rod leading screw, and is slided even with push rod slide mechanism by push rod connecting plate Connecing, reaction cup is pushed described PMT light-metering assembly through described second reaction tray and detects by described push rod upper end.
Described push rod slide mechanism includes that line slide rail and slide block, the upper surface of described push rod base plate are provided with slide rail and install Seat, described line slide rail is vertically arranged, and described slide block side is slidably connected with described line slide rail, opposite side and push rod connecting plate It is connected.
Being positioned at described first on described second disk cover to wash plate hole side and be provided with the second reagent adding hole, described second disk cover is upper Wash plate hole side in described second to be provided with and add substrate hole.
Described first lifting module is identical with the second lifting modular structure, all includes lifting motor, motor mounting plate, lifting Screw mandrel and vertical sliding panel, described lifting motor is fixed on motor mounting plate, is provided with and leads on the upper surface of motor mounting plate Rail vertical plate, described guide rail vertical plate is vertically provided with guide rail, and described vertical sliding panel and described guide rail vertical plate pass through guide rail Being slidably connected, the lower end of described elevating screw is connected with the outfan of described lifting motor, and feed screw nut and institute are passed through in upper end State vertical sliding panel to be connected.
Described first wash plate module include the first cleaning needle base plate, some first pins fix seat, some first injection needle and Some first aspirating needles, described vertical sliding panel upper end is provided with the first cleaning support location-plate, and described first cleaning needle base plate leads to Crossing the first locking nut to be fixed on described first and clean on support location-plate, described first injection needle and the first aspirating needle are by the One pin is fixed seat and is slidably connected with described first cleaning needle base plate, and described first pin is fixed seat lower surface and is provided with oilless bushing, Described oilless bushing inserts in described first cleaning needle base plate, and described first pin is fixed and is provided with bullet also by spring lead on seat Spring, described spring housing is located on spring lead;Second cleaning module includes that the second cleaning needle base plate, some second pins are fixed Seat, some second injection needle, some second aspirating needles and substrate pin, it is fixed that described vertical sliding panel upper end is provided with the second cleaning support Position plate, described second cleaning needle base plate is fixed on described second cleaning support location-plate by the second locking nut, and described the Two injection needle, the second aspirating needle and substrate pin are fixed seat by the second pin and are slidably connected with described second cleaning needle base plate.
Described reagent disc bag reagent pot, reagent rotor and the second pulley arrangement, described reagent rotor is located at described reagent pot Inside, the center of described reagent rotor is provided with second and fixes axle, and described second fixes the lower end of axle and described second belt wheel dress Putting and be connected, under the drive of the second pulley arrangement, described reagent rotor is around the second solid fixed-axis rotation, table on described reagent rotor Face is provided with some reagent bottle being distributed in divergent shape, and the upper end of described reagent pot is provided with reagent disk cover.
Described reagent disc also includes that ventilating system, described ventilating system include dehumidify fan and air channel, described dehumidifying fan Being located on the upper surface of reagent rotor, one end, described air channel is positioned at below reagent rotor, and the other end extends reagent pot outward flange Outside.
Described reagent disc also includes that barcode machine, the sidewall of described reagent pot are provided with scanning mouth, and described barcode machine is positioned at institute State outside scanning mouth, the bar code on described barcode machine scanning reagent bottle.
Described sample introduction frame includes that housing, support, injector handgrip and some sample racks, the arrangement of described sample rack are located at support On, each sample rack to be placed several test tubes, described support has been horizontally disposed with injector slide rail, described injector handgrip is sliding Moving and be located on described injector slide rail, described support is additionally provided with horizontal sliding motor, described horizontal sliding motor passes through handgrip Timing Belt drives described injector handgrip level on injector slide rail to slide, and on described support, also level is slided and is provided with sample-adding Position, described housing is provided with well at opposite position.
Described sample-adding position includes being loaded position slide rail, sample-adding position motor and some pallets, and described pallet is provided with sample rack, institute Stating sample-adding position slide rail level and be parallel to each other with injector slide rail and be located at injector slide rail rear, described pallet is by sample-adding position Slide mechanism is slidably connected with described sample-adding position slide rail, and described sample-adding position motor drives pallet along adding by sample-adding bit synchronization band Sample position slide rail slides.
Described sample-adding position slide mechanism includes being loaded position slide block and sample-adding position take-up housing, and described sample-adding position slide block adds with described Sample position slide rail is slidably connected, and described sample-adding position take-up housing is located at above the slide block of described sample-adding position, and described sample-adding is located at by described pallet Above the take-up housing of position.
Described sample-adding position includes that two pallets, two pallets are connected by connecting seat.
Described reagent adding module includes that reagent needle assembly, rotating mechanism and elevating mechanism, described elevating mechanism pass through reagent Pin base plate is installed on support body, and described rotating mechanism is fixed on elevating mechanism top, described examination by rotating mechanism mounting base Agent needle assembly is connected with rotating mechanism and elevating mechanism respectively.
Described reagent needle assembly includes that reagent pin and reagent needle arm, the syringe needle of described reagent pin are vertically arranged downwards, upper end Protect set to slide with described reagent needle arm by reagent pin to arrange, described reagent needle arm is positioned at reagent pin and is arranged over bearing pin admittedly Determining plate, described bearing pin fixed plate is provided with bearing pin, and the lower end of described bearing pin is through reagent pin protection set, and overlaps with the protection of reagent pin Being slidably connected, the connection of described reagent pin upper end is provided with reagent needle adapter.
The outside of described reagent pin upper end is provided with the reagent pin guide pin bushing arranged with reagent coaxial needle.
Described rotating mechanism includes ball spline pair, electric rotating machine, electric rotating machine mounting base and the 3rd driving device, institute Stating ball spline pair upper end to be connected with reagent needle arm, lower end is from top to down through electric rotating machine mounting base, described electric rotating Machine drives ball spline pair to rotate by the 3rd driving device, and then drives reagent needle assembly to rotate around ball spline pair.
Described 3rd driving device includes the 3rd driving pulley, the 3rd driven pulley and the 3rd Timing Belt, and the described 3rd is main Movable belt pulley is located at the outfan of electric rotating machine, and the 3rd driven pulley is set in outside ball spline pair, and the 3rd driven pulley passes through 3rd Timing Belt and the 3rd driving pulley are connected.
Described elevating mechanism includes upper and lower motor, reagent pin slide rail and the 4th driving device, and described upper and lower motor passes through pin Seat side plate is fixed on reagent pin base plate, and reagent pin slide rail is vertically located on rotating mechanism mounting base, described ball spline pair Lower end is slidably connected with reagent pin slide rail by installing plate, when upper and lower motor drives installing plate along examination by the 4th driving device Agent pin slide rail moves up and down, and then drives reagent needle assembly to move up and down.
Described 4th driving device includes the 4th driving pulley, the 4th driven pulley and the 4th Timing Belt, the 4th main belt Wheel is located at the outfan of upper and lower motor, and the 4th driven pulley is located on needle stand side plate by the 4th driven belt wheel seat, and the 4th is driven Belt wheel is connected by the 4th Timing Belt and the 4th driving pulley, is equipped with reagent pin slide block with described reagent pin slide rail, On the one hand described reagent pin slide block is connected with installing plate by the second belt fixture block, is on the other hand connected with the 4th Timing Belt Connect.
This utility model is had the benefit that
In this utility model, described full-automatic illumination immunity analysis instrument includes shell, support body, sample introduction frame, reaction cup storehouse, anti- Should coil, reagent disc, sample-adding module, reagent adding module, liquid circuit module, detection module and control module, described sample introduction frame will be for will Sample in test tube is added to, by sample-adding module, the reaction cup that is positioned in reaction tray, and described reaction cup storehouse is in order and exactly Reaction cup being delivered in reaction tray, described reaction tray includes the first reaction tray and the second reaction tray, carries out in the first reaction tray Sample-adding, reagent adding, dilute, the operation such as hatch, by the first push rod component, reaction cup is pushed to the second reaction tray the most again and enter Row is hatched, reagent adding, wash plate, add substrate, detect, throw the operation such as cup, and above procedure is in the first reaction tray and the second reaction tray Ruly carry out, and effectively prevent cross-contamination, it is ensured that the result of detection, need during reaction by adding Reagent is added in reaction cup by reagent modules, and described liquid circuit module ensure that flowing and the flow direction of liquid during whole detection, Described detection module sample after terminating reaction detects, then reaches a conclusion, and described control module is used for controlling The various actions of whole instrument.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, this utility model is described in further detail.
Fig. 1 is the structural representation of full-automatic illumination immunity analysis instrument described in the utility model.
Fig. 2 is the structural representation that full-automatic illumination immunity analysis instrument described in the utility model removes shell.
Fig. 3 is the top view that full-automatic illumination immunity analysis instrument described in the utility model removes shell.
Fig. 4 is the structural representation in reaction cup storehouse described in the utility model.
Fig. 5 is the structural representation that double-pole device is removed in reaction cup storehouse described in the utility model.
Fig. 6 is the structural representation that shell is removed in reaction cup storehouse described in the utility model.
Fig. 7 is the profile that double-pole device is removed in reaction cup storehouse described in the utility model.
Fig. 8 is the structural representation of double-pole device described in the utility model.
Fig. 9 is the assembling figure of reaction cup pipe described in the utility model and reaction cup.
Figure 10 is the structural representation of reaction cup pipe described in the utility model.
Figure 11 is the structural representation of reaction tray described in the utility model.
Figure 12 is that reaction tray described in the utility model removes the structural representation cleaning device.
Figure 13 is that reaction tray described in the utility model removes the first disk cover and the structural representation of the second disk cover.
Figure 14 is the structural representation of the first reaction tray described in the utility model.
Figure 15 is the structural representation of the second reaction tray described in the utility model.
Figure 16 is the structural representation of push rod component described in the utility model.
Figure 17 is the structural representation of the described in the utility model first the first state cleaning device.
Figure 18 is the structural representation of the described in the utility model first the second state cleaning device.
Figure 19 is the described in the utility model second structural representation cleaning device.
Figure 20 is the structural representation of the first blocking mechanism described in the utility model.
Figure 21 is the structural representation that the first blocking mechanism described in the utility model removes the first positioning plate.
Figure 22 is the structural representation of the first link gear described in the utility model.
Figure 23 is the structural representation of reagent disc described in the utility model.
Figure 24 is the profile of reagent disc described in the utility model.
Figure 25 is the structural representation that reagent disc described in the utility model removes reagent disk cover.
Figure 26 is that reagent disc described in the utility model removes reagent disk cover and the structural representation of cover plate.
Figure 27 is the structural representation of sample introduction frame described in the utility model.
Figure 28 is the structural representation that housing removed by sample introduction frame described in the utility model.
Figure 29 is the top view that housing removed by sample introduction frame described in the utility model.
Figure 30 is the structural representation of sample-adding position described in the utility model.
Figure 31 is the explosive view of sample-adding position described in the utility model.
Figure 32 is the structural representation of injector handgrip described in the utility model.
Figure 33 is the structural representation of handgrip assembly the first state described in the utility model.
Figure 34 is the structural representation of handgrip assembly the second state described in the utility model.
Figure 35 is the structural representation of reagent pin the first state described in the utility model.
Figure 36 is reagent pin described in the utility model and the structural representation of state.
Figure 37 is the structural representation of reagent needle assembly described in the utility model.
The label that in figure, component names is corresponding is as follows:
1, shell;2, support body;3, reaction cup storehouse;31, the first base plate;32, first axle is fixed;33, the first motor;34, anti- Answer cup pipe;35, reaction cup;36, reaction top rotary table;37, reaction lower rotary table;38, double-pole motor;39, screw mandrel;310, double-pole Bearing;311, double-pole guide rail;312, double-pole slide block;313, support;314, gripper shoe;315, yardstick;316, cup sensing is pushed away Device;317, cavity;318, shell fragment;319, reaction cup pipe clamp groove;320, reaction tube intermediate plate;321, through hole;322, sensing section; 323, reaction cup storehouse motion sensor;324, scanner;325, scanner window;326, the first axle sleeve;327, clutch shaft bearing; 328, the first big belt wheel;329, the first small pulley;330, the first belt;331, light barrier;332, reaction cup storehouse overhead door;333, draw Button;334, overhead door signal transducer;335, reaction cup storehouse pillar;336, pushing block;4, the first reaction tray;41, reaction tray installs the end Plate;42, the first disk body;43, the first disk cover;44, the first rotating disk;45, arc notch;46, the first reagent adding hole;47, reagent is dilute Release hole;48, well;49, sample-adding dilution holes;410, the first push rod component;411, the first code-disc;412, the first counting sensing Device;5, the second reaction tray;51, the second disk body;52, the second disk cover;53, the second rotating disk;54, first plate hole is washed;55, second plate is washed Hole;56, the first positioning plate;57, the first direct current generator;58, the first guide shaft;59, the first guide shaft support;510, first connects Bar;511, the first cam;512, guide shaft alignment pin;513, sensing catch;514, optocoupler sensor;515, linear bearing;516、 Circlip for shaft;517, PMT light-metering assembly;518, push rod base plate;519, DC stepper motor;520, push rod;521, push rod Leading screw;522, push rod connecting plate;523, line slide rail;524, slide block;525, slide rail mounting seat;526, the second reagent adding hole; 527, substrate hole is added;528, lifting motor;529, motor mounting plate;530, elevating screw;531, vertical sliding panel;532, guide rail Vertical plate;533, guide rail;534, feed screw nut;535, the first cleaning needle base plate;536, seat fixed by the first pin;537, the first fluid injection Pin;538, the first aspirating needle;539, first support location-plate is cleaned;540, the first locking nut;541, oilless bushing;542, bullet Spring lead;543, spring;544, the second cleaning needle base plate;545, seat fixed by the second pin;546, the second injection needle;547, second Aspirating needle;548, substrate pin;549, second support location-plate is cleaned;550, the second locking nut;551, cup passage is thrown;552, the end Thing bottle;6, reagent disc;61, reagent pot;62, reagent rotor;63, second axle is fixed;64, reagent bottle;65, reagent disk cover;66, remove Wet wind is fanned;67, air channel;68, barcode machine;69, scanning mouth;610, dust extraction fan;611, reagent disc motor;612, second actively Wheel;613, the second driven pulley;614, the second belt;615, transfer block;616, cover plate;7, injector;71, housing;72, support; 73, sample rack;74, test tube;75, injector slide rail;76, horizontal sliding motor;77, handgrip Timing Belt;78, well;79, add Sample position base plate;710, sample-adding position slide rail;711, sample-adding position motor;712, pallet;713, sample-adding bit synchronization band;714, sample-adding position is sliding Block;715, sample-adding position take-up housing;716, seat is connected;717, zero-position stopping piece;718, zero-bit inductive switch;719, handgrip plate;720、 Motor up and down;721, electric rotating machine;722, elevating screw;723, splined shaft;724, screw mandrel spline connecting plate;725, handgrip Installing plate;726, handgrip motor;727, left handgrip;728, right handgrip;729, cam;730, handgrip slide rail;731, left handgrip is sliding Block;732, right handgrip slide block;733, left handgrip mounting seat;734, right handgrip mounting seat;735, bearing rotating shaft;736, the 3rd axle Hold;737, spring base;738, emergency diagnosis position;739, carriage baffle plate;8, sample-adding module;9, reagent adding module;91, at the bottom of reagent pin Plate;92, rotating mechanism mounting base;93, reagent pin;94, reagent needle arm;95, bearing pin;96, reagent pin protection set;97, bearing pin Fixed plate;98, reagent needle adapter;99, reagent pin guide pin bushing;910, charge sensors;911, sensing catch;912, ball spline Secondary;913, electric rotating machine;914, electric rotating machine mounting base;915, the 3rd driving pulley;916, the 3rd driven pulley;917, Three Timing Belts;918, upper and lower motor;920, reagent pin slide rail;921, needle stand side plate;922, installing plate;923, the 4th main belt Wheel;924, the 4th driven pulley;925, the 4th Timing Belt;926, the 4th driven belt wheel seat;927, reagent pin slide block;928, belt Fixture block;929, ball bearing;10, detection module.
Detailed description of the invention
Below in conjunction with the accompanying drawings and this utility model is described in further detail by embodiment:
As the embodiment of full-automatic illumination immunity analysis instrument described in the utility model, as shown in Figure 1, Figure 2 and Figure 3, bag Include shell 1, support body 2, sample introduction frame 7, reaction cup storehouse 3, reaction tray, reagent disc 6, sample-adding module 8, reagent adding module 9, liquid circuit module (not shown), detection module 10 and control module (not shown), described reaction cup storehouse 3, reaction tray, reagent disc 6, add Original mold block 8, reagent adding module 9 are all located on support body 2, and it is outside that described shell 1 is covered in described support body 2, and described reaction tray includes First reaction tray 4 and the second reaction tray 5, described first reaction tray 4 side is positioned at below described reaction cup storehouse 3, described reaction tray, Reagent disc 6, sample-adding module 8 are all connected with liquid circuit module with reagent adding module 9, described sample introduction frame 7, reaction cup storehouse 3, reaction Dish, reagent disc 6, sample-adding module 8, reagent adding module 9, liquid circuit module, detection module 10 all electrically connect with control module.
Reaction cup storehouse 3 as shown in Fig. 4 to Figure 10 include shell 1, double-pole device, the first base plate 31, first fix axle 32, First motor 33, reaction cup pipe 34, reaction cup 35, reaction top rotary table 36 and reaction lower rotary table 37, described shell 1 is fixed first Axle the 32, first motor 33, reaction cup pipe 34, reaction cup 35, reaction top rotary table 36 and reaction lower rotary table 37 are wrapped in inside, described First lower end fixing axle 32 is fixed on described first base plate 31, and described reaction top rotary table 36 and reaction lower rotary table 37 overlap respectively It is loaded on the described first top and bottom fixing axle 32, and solid around first under the drive of the first motor 33 and the first pulley arrangement Dead axle 32 rotates, and it is internal that reaction cup pipe 34 is located in the superposition of described reaction cup 35, and the top and bottom of described reaction cup pipe 34 are respectively Being installed on reaction top rotary table 36 and reaction lower rotary table 37, described double-pole device is fixed on described first end by support means On plate 31, double-pole device is positioned at above described reaction top rotary table 36, and is positioned at directly over reaction cup pipe 34.Pass through double-pole Device is released being superimposed upon the reaction cup 35 within reaction cup pipe 34 downwards, and the reaction cup 35 of release drops in reaction On relevant position on dish, after the reaction cup 35 in a reaction cup pipe 34 makes to be finished, the first motor 33 rotates, and then band Dynamic reaction top rotary table 36 and reaction lower rotary table 37 rotate, and are removed by empty reaction cup pipe 34 below double-pole device, another The reaction cup pipe 34 filling reaction cup 35 moves to immediately below double-pole device.
In the present embodiment, described double-pole device includes two double-pole motors 38, two screw mandrels 39, double-pole bearings 310, two double-pole guide rails 311 and two pieces of double-pole slide blocks 312, described support means includes support 313 and gripper shoe 314, Described gripper shoe 314 is fixed on described first base plate 31 by support 313, described double-pole bearing 310 and two double-poles Motor 38 is parallel to each other on the surface being fixed on described gripper shoe 314, and two double-pole guide rails 311 are vertical and parallel are fixed on On double-pole bearing 310, two pieces of double-pole slide blocks 312 are slidably connected with two double-pole guide rails 311 respectively, two screw mandrels 39 times End is connected with two double-pole motor 38 spirals respectively, and upper end is connected with two pieces of double-pole slide blocks 312 respectively.When double-pole electricity When machine 38 rotates, screw mandrel 39 moves downward, and then withstands the reaction cup 35 within reaction cup pipe 34, after the segment distance that moves, In reaction cup pipe 34, a nethermost reaction cup 35 departs from reaction cup pipe 34, and the double-pole slide block 312 of screw mandrel 39 upper end is same Along double-pole guide rail 311 slide downward.
In the present embodiment, the side that described double-pole bearing 310 is positioned at double-pole guide rail 311 is vertically provided with a yardstick 315, described double-pole slide block 312 is positioned at described yardstick 315 side and is provided with and pushes away glass sensor 316, described in push away glass sensor 316 Follow double-pole slide block 312 to move up and down, and counted by yardstick 315.By yardstick 315 with push away glass sensor 316 Counting is it is apparent that internal remaining reaction cup 35 quantity of reaction cup pipe 24.
In the present embodiment, described reaction cup pipe 34 includes that two cavitys being parallel to each other 317, reaction cup 35 superposition put into two In individual cavity 317, the lower end of reaction cup pipe 34 is provided with shell fragment 318 around two cavitys 317.Set above reaction cup 35 topmost Being equipped with a pushing block 336, described screw mandrel 39 lower end is inconsistent with described pushing block 336.The modes of emplacement of superposing type can be effectively sharp With space, and then reduce reaction cup 35 and place region, described shell fragment 318 the reaction that can effectively clamp bottom is set Cup 35.
In the present embodiment, the neighboring of described reaction top rotary table 36 is provided with a circle reaction cup pipe clamp groove 319, each reaction Being provided with reaction tube intermediate plate 320 in cup pipe clamp groove 319, described reaction lower rotary table 37 is provided with a circle and described reaction cup pipe clamp groove phase Corresponding through hole 321, the quantity of described through hole 321 is the twice of reaction cup pipe clamp groove 319, and two through holes 321 are anti-for one Answering cup pipe clamp groove 319, the upper end of reaction cup pipe 34 snaps in described reaction tube intermediate plate 320, and lower end is inserted in two through holes 321. By reaction cup pipe 34 is placed in reaction cup pipe clamp groove 319, and by the fixed form of reaction tube intermediate plate 320, convenient use Reaction cup pipe is changed at family.
In the present embodiment, described reaction top rotary table 36 is provided with sensing section 322, and described gripper shoe 314 is provided with reaction Cup storehouse motion sensor 323, described sensing section 322 and reaction cup storehouse motion sensor 323 are positioned on same circumference.Described instead Cup storehouse motion sensor 323 and arranging of sensing section 322 is answered can effectively to record making of reaction cup storehouse 3 internal-response cup pipe 34 Use situation.
In the present embodiment, described reaction cup storehouse 3 also includes scanner 324, is provided with scanner window 325 on shell 1.
In the present embodiment, described first fixes axle 32 outer cover is provided with the first axle sleeve 326, described first axle sleeve 326 and One fixes and is provided with two clutch shaft bearings 327 between axle 32, and described first pulley arrangement includes first big belt wheel the 328, first small band Wheel 329 and first belt 330, described first small pulley 329 is fixed on the outfan of described first motor 33, described first big Belt wheel 328 is installed on the lower end of described first axle sleeve 326, by the first belt 330 by the first big belt wheel 328 and the first small pulley 329 are connected.
In the present embodiment, between described reaction top rotary table 36 and reaction lower rotary table 37, it is provided with three pieces of light barriers 331.
In the present embodiment, described shell 2 includes a reaction cup storehouse overhead door 332, and the top of reaction cup storehouse overhead door 332 is with outer Remaining position of shell 1 is hinged, and bottom is fixed by pulling buckle 333, and is provided with overhead door sensing at reaction cup storehouse overhead door 332 Device 334.Using the opening ways of upset, user operation is more convenient, and arranges overhead door signal transducer 334 and can effectively supervise The open and-shut mode of control reaction cup storehouse overhead door 332.
In the present embodiment, the lower surface of described first base plate 31 is provided with reaction cup storehouse pillar 335, is propped up by reaction cup storehouse Reaction cup storehouse 3 is fixed in support body (not shown) by post 335.
Reaction tray as shown in Figure 11 to Figure 22 includes the first reaction tray 4 and the second reaction tray 5, described first reaction tray 4 He Second reaction tray 5 is mounted on reaction tray mounting base 41, and the reaction cup 35 in the first reaction tray 4 is by the first push rod component 410 push in the second reaction tray 5, and described first reaction tray 4 includes first disk body the 42, first disk cover the 43, first rotating disk 44 and First driving device, described first rotating disk 44 is located in the first disk body 42, and the first disk cover 43 is covered in the first disk body 42 top, and Being positioned at above the first rotating disk 44, the first rotating disk 44 rotates under the drive of the first driving device;Second reaction tray 5 includes the second dish Body the 51, second disk cover the 52, second rotating disk 53 and the second driving device, described second rotating disk 53 is located in the second disk body 51, and second Disk cover 52 is covered in the second disk body 51 top, and is positioned at above the second rotating disk 53, and the second rotating disk 53 is at the band of the second driving device Dynamic lower rotation, described first disk cover 43 is provided with arc notch 45, and described first disk cover 43 is provided with the first reagent adding hole 46, examination Dilution agent hole 47, well 48 and sample-adding dilution holes 49.The operations such as described first reaction tray 4 is used for being loaded, reagent adding, dilution, The operations such as the second reaction tray 5 is used for cleaning, detection, the first reaction tray 4 and the second reaction tray 5 all can rotate, and then realize with On various operations, arranging of described arc notch 45 facilitates reaction cup to fall in reaction cup storehouse the first reaction tray 4.
In the present embodiment, described second reaction tray 5 is provided with the first cleaning device and second and cleans device, described second dish Lid 52 is provided with first and washes plate hole 54 and second and wash plate hole 55, described first clean device include first wash plate module, first liter Fall module and the first blocking mechanism, described first washes plate module is located at the first lifting module top, and is positioned at first and washes plate hole 55 Top, described first blocking mechanism is located at first and is washed plate module side;Described second clean device include the second cleaning module and Second lifting module, described second cleaning module is located at the second lifting module top, and is positioned at second and washes above plate hole 55;Described First blocking mechanism includes the first positioning plate 57, five the first guide shafts 58 of 56, five the first direct current generators and five first Motivation structure, described first guide shaft 58 one end is set in parallel in described first positioning plate 56 upper surface by the first guide shaft support 59 On, the other end and the first link gear are connected, the outfan of described first direct current generator 57 and described first link gear phase Connect, and then drive the first guide shaft 58 to move along a straight line along the first guide shaft support 59.Clean sometimes for two sometimes for single order Rank are cleaned, so arranging two to clean device, because the reagent that the reagent of single order cleaning and two rank are cleaned is likely to be is mixed in one Rising, that is accomplished by being controlled with a blocking mechanism, when needing single order to clean, will stop at first cleaning positions Aspirating needle and injection needle do not allow them go down cleaning, the when of needing two rank to clean, can guarantee that again under aspirating needle and injection needle Go to be carried out.
In the present embodiment, described first link gear includes head rod 510 and the first cam 511, described first convex Wheel 511 is located at the outfan of described first direct current generator 57, and one end of described head rod 510 rotates with the first cam 511 Connecting, the other end is rotationally connected with described first guide shaft 58, and is fixed diametrically by guide shaft alignment pin 512.When first is straight When stream motor 57 rotates, under the effect of the first cam 511 and head rod 510, the first guide shaft 58 props up along the first guide shaft Frame 59 horizontal linear moves, and then stop first is washed and moved downward in plate module.
In the present embodiment, the lower end of described guide shaft alignment pin 512 is provided with sensing catch 513, described first positioning plate 56 The upper position corresponding with described sensing catch 513 is provided with optocoupler sensor 514;It is arranged with straight line on described first guide shaft 58 Bearing 515, described linear bearing 515 frame is on described first guide shaft support 59, and passes through two circlips for shaft 516 at axle To upper limit.The arranging of described sensing catch 513 and optocoupler sensor 513 can monitor first accurately and wash in plate module each The motion of pin.
In the present embodiment, described second reaction tray is additionally provided with PMT light-metering assembly 517, is positioned under described second reaction tray Side and just described PMT light-metering assembly 517 is being provided with the second push rod component, described second push rod component include push rod base plate 518, DC stepper motor 519, push rod 520 and push rod slide mechanism, described DC stepper motor 519 is located at described push rod base plate 518 On lower surface, and the outfan of DC stepper motor 519 is provided with push rod leading screw 521, and described push rod is located at by described push rod 520 The upper end of leading screw 521, and be slidably connected with push rod slide mechanism by push rod connecting plate 522, described push rod 520 upper end passes institute State the second reaction tray 5 reaction cup 35 pushes described PMT light-metering assembly 517 to detect.The structure of the first push rod component and the The structure of two push rod component is identical.It is positioned at described PMT light-metering assembly 517 side below described second disk body 51 and is provided with throwing cup passage 551.When reaction cup 35 moves to PMT light-metering assembly 517, by the second push rod component, reaction cup 35 is upwards headed into Detect in PMT light-metering assembly 517, after the liquid detecting in reaction cup 35 completes, rotate the second rotating disk 53, will detect Reaction cup 35 move to throwing above cup passage 551, can realize throwing cup operation.
In the present embodiment, described push rod slide mechanism includes line slide rail 523 and slide block 524, described push rod base plate 518 Upper surface is provided with slide rail mounting seat 525, and described line slide rail 523 is vertically arranged, and described slide block 524 side is sliding with described straight line Rail 523 is slidably connected, and opposite side is connected with push rod connecting plate 522.
In the present embodiment, described second disk cover 52 is positioned at described first and washes plate hole 54 side and be provided with the second reagent adding hole 526, described second disk cover 52 is positioned at described second and washes plate hole 55 side and be provided with and add substrate hole 527.It is provided with in reaction tray side Substrate bottle 552.
In the present embodiment, described first lifting module with second lifting modular structure identical, all include lifting motor 528, Motor mounting plate 529, elevating screw 530 and vertical sliding panel 531, described lifting motor 528 is fixed on motor mounting plate 529 On, the upper surface of motor mounting plate 529 is provided with guide rail vertical plate 532, described guide rail vertical plate 532 is vertically provided with guide rail 533, described vertical sliding panel 531 is slidably connected by guide rail 533 with described guide rail vertical plate 532, described elevating screw 530 Lower end is connected with the outfan of described lifting motor 528, and feed screw nut 534 and described vertical sliding panel 531 phase are passed through in upper end Connect.
In the present embodiment, described first wash plate module include 535, five the first pins of the first cleaning needle base plate fix seat 536, Five the first injection needle 537 and five the first aspirating needles 538, it is fixed that described vertical sliding panel 531 upper end is provided with the first cleaning support Position plate 539, described first cleaning needle base plate 535 is fixed on described first by the first locking nut 540 and cleans support location-plate On 539, described first injection needle 537 and the first aspirating needle 538 fix seat 536 and described first cleaning needle base plate by the first pin 535 are slidably connected, and described first pin is fixed seat 536 lower surface and is provided with oilless bushing 541, and described oilless bushing 541 inserts institute Stating in the first cleaning needle base plate 535, described first pin is fixed and is provided with spring 543, institute also by spring lead 542 on seat 536 State spring 543 to be sheathed on spring lead 542;Second cleaning module includes that 544, five the second pins of the second cleaning needle base plate are solid Reservation 546, five the second aspirating needles 547 of 545, five the second injection needle and substrate pin 548, described vertical sliding panel 531 upper end Being provided with the second cleaning support location-plate 549, described second cleaning needle base plate 544 is fixed on described by the second locking nut 550 Second cleans on support location-plate 549, and described second injection needle the 546, second aspirating needle 547 and substrate pin 548 are by the second pin Fixing seat 545 is slidably connected with described second cleaning needle base plate 544.
In the present embodiment, being provided with the first code-disc 411 below described first rotating disk 44, corresponding is provided with the first counting sensing Device 412.Described first code-disc 411 and the first sensor for countering 412 the rotation that can preferably monitor the first reaction tray 4 is set Position.
In the present embodiment, being provided with the second code-disc (not shown) below described second rotating disk, corresponding is provided with second Sensor for countering (not shown).It is anti-that the arranging of described second code-disc and the second sensor for countering can preferably monitor second The turned position of 5 should be coiled.
Reagent disc 6 as shown in Figure 23 to Figure 26 includes reagent pot 61, reagent rotor 62 and the second pulley arrangement, described examination It is internal that described reagent pot 61 is located at by agent rotating disk 62, and the center of described reagent rotor 62 is provided with second and fixes axle 63, and described second The lower end of fixing axle 63 is connected with described second pulley arrangement, under the drive of the second pulley arrangement described reagent rotor 62 around Second fixes axle 63 rotates, and described reagent rotor 62 upper surface is provided with 25 reagent bottle 64 being distributed in divergent shape, institute The upper end stating reagent pot 61 is provided with reagent disk cover 65.Institute's reagent pot 61, as outer layer protection housing, can effectively keep inside Temperature, described reagent disk cover 65 preferably plays the effect of sealing.
In the present embodiment, described reagent disc 6 also includes that ventilating system, described ventilating system include dehumidify fan 66 and air channel 67, described dehumidifying fan 66 is located on the upper surface of reagent rotor 62, and one end, described air channel 67 is positioned at below reagent rotor 62, separately One end is extended outside reagent pot 61 outward flange.Described dehumidifying fan 66 and arranging of air channel 67 can effectively discharge reagent disc Dampness within 6, and then ensure the external environment condition of reagent storage.
In the present embodiment, described reagent disc 6 also includes that barcode machine 68, the sidewall of described reagent pot 61 are provided with scanning mouth 69, it is outside that described barcode machine 68 is positioned at described scanning mouth 69, and described barcode machine 68 scans the bar code on reagent bottle 64.Described bar code Arranging of machine 68 can record the kind on reagent bottle 64 accurately, can effectively, accurately during the later stage extracts reagent Extraction.
In the present embodiment, described barcode machine 68 side is provided with dust extraction fan 610.
In the present embodiment, described second pulley arrangement includes that reagent disc motor the 611, second drivewheel 612 and second is driven Wheel 613, described second drivewheel 612 is located at the outfan of described reagent disc motor 611, and described second driven pulley 613 is set in Second fixes on axle 63, and is connected with the second drivewheel 612 by the second belt 614.Under the drive of the second pulley arrangement, Required reagent, around axis rotation, is turned to carry out at reagent pin reagent extraction by described reagent rotor 62.
In the present embodiment, described reagent disk cover 65 is flip-shell.Reagent disk cover 65 uses the form renovated, it is simple to user is only Need to open to renovate and take and place reagent bottle, close in the rest of the cases and renovate, the close of reagent disc can be better ensured that Feng Xing.
In the present embodiment, described reagent rotor 62 upper surface be provided with six in divergent shape distribution be positioned on same circumference Transfer block 615, be arranged over one piece of cover plate 616 in transfer block 615, described second fixes axle 63 and dehumidifying fan 66 is positioned at lid Below plate 616.
Sample introduction frame 9 as shown in Figure 27 to Figure 34 includes housing 71, support 72, injector handgrip and 25 sample racks 73, the arrangement of described sample rack 73 is located on support 72, and each sample rack 73 is placed several test tubes 74, water on described support 72 The flat injector slide rail 75 that is provided with, the slip of described injector handgrip is located on described injector slide rail 75, on described support 73 also Being provided with horizontal sliding motor 76, described horizontal sliding motor 76 drives described injector handgrip at sample introduction by handgrip Timing Belt 77 On device slide rail 75, level is slided, and on described support 72, also level is slided and is provided with sample-adding position, on described housing 71 at opposite position It is provided with well 78.Described housing 71, as outer protection parts, makes the sample-adding of sample in a space the most airtight Inside carrying out, and then reduce cross-contamination, described injector handgrip may be used for capturing sample rack 73, and by sample rack 73 at water Square translate up, and sample rack 73 can be made rotation process, be placed into being loaded at position, after sample-adding terminates again It is recycled to streamline;Only a well 78 is set on housing 71, further reduces the cross-contamination of sample.
In the present embodiment, described sample-adding position includes being loaded position base plate 79, sample-adding position slide rail 710, sample-adding position motor 711 and two Individual pallet 712, two pallets 712 are connected by connecting seat 716, and described pallet 712 is provided with sample rack 73, described sample-adding position Slide rail 710 level is located on sample-adding position base plate 79, and is parallel to each other with injector slide rail 75 and is located at injector slide rail 75 rear, Described pallet 712 is slidably connected with described sample-adding position slide rail 710 by sample-adding position slide mechanism, and described sample-adding position motor 711 leads to Crossing sample-adding bit synchronization band 713 drives pallet 712 to slide along sample-adding position slide rail 710.Need to extract sample in which test tube 74, Only need to move the sample rack 73 on pallet 712.
In the present embodiment, described sample-adding position slide mechanism includes being loaded position slide block 714 and sample-adding position take-up housing 715, described Sample-adding position slide block 714 is slidably connected with described sample-adding position slide rail 710, and it is sliding that described sample-adding position take-up housing 715 is located at described sample-adding position Above block 714, described pallet 712 is located at above described sample-adding position take-up housing 715.
In the present embodiment, it is provided with zero-position stopping piece 717, sample-adding position motor near pallet 712 one end of sample-adding position motor 711 The inner side of 711 is provided with zero-bit inductive switch 718, and described zero-position stopping piece 727 and zero-bit inductive switch 718 cooperate setting.
In the present embodiment, described injector handgrip includes handgrip plate 719, upper and lower motor 720, electric rotating machine 721, rises Fall screw mandrel 722, splined shaft 723 and handgrip assembly, what described elevating screw 722 and splined shaft 723 were parallel to each other is vertically located at institute Stating on handgrip plate 719, the outfan of described upper and lower motor 720 is connected with the upper end of described elevating screw 722, described rotation The outfan of rotating motor 721 is connected with the upper end of described splined shaft 723, and described handgrip assembly is placed on described splined shaft 723, It is arranged with screw mandrel spline connecting plate 724, described screw mandrel spline connecting plate 724 on described elevating screw 722 and splined shaft 723 simultaneously It is positioned at below described handgrip assembly.
In the present embodiment, described handgrip assembly includes that handgrip installing plate 725, handgrip motor 726, left handgrip 727 and the right side are grabbed Hands 728, described handgrip motor 726 is installed on the upper surface of described handgrip installing plate 725, described handgrip motor 726 outfan Being provided with cam 729, the lower surface of described handgrip installing plate 725 is provided with two symmetrical handgrip slide rails 730, every handgrip Being respectively equipped with left handgrip slide block 731 and right handgrip slide block 732 on slide rail 730, described left handgrip 727 and right handgrip 728 lead to respectively Cross left handgrip mounting seat 733 and right handgrip mounting seat 734 slided and is located on described left handgrip slide block 731 and right handgrip slide block 732, A bearing rotating shaft 735, every bearing rotating shaft 735 it is respectively equipped with in described left handgrip mounting seat 733 and right handgrip mounting seat 734 Being provided with the 3rd bearing 736, two the 3rd bearings 736 are symmetrically set in described cam 729 both sides, described left handgrip mounting seat 733 and right handgrip mounting seat 734 on be respectively equipped with a spring base 737, be provided with extension spring between two spring bases 737 (in figure not Illustrate).
In the present embodiment, described sample introduction frame 7 is additionally provided with three emergency diagnosis positions 738, and each emergency diagnosis position 738 is placed a sample This 73.
In the present embodiment, described sample-adding position base plate 79 is positioned at slide rail 710 side, described sample-adding position and is provided with carriage baffle plate 739。
Reagent adding module 9 as shown in Figure 35, Figure 36 and Figure 37 includes reagent needle assembly, rotating mechanism and elevating mechanism, Described elevating mechanism is installed by reagent pin base plate 91, and described rotating mechanism is fixed on by rotating mechanism mounting base 92 Elevating mechanism top, described reagent needle assembly is connected with rotating mechanism and elevating mechanism respectively, and described reagent needle assembly includes Reagent pin 93, reagent needle arm 94 and buffer gear, the syringe needle of described reagent pin 93 is vertically arranged downwards, and described buffer gear includes Bearing pin 95 and reagent pin protection set 96, the outsides that described reagent pin protection set 96 is set in reagent pin 93 upper end, and with described examination Agent needle arm 94 is slided and is arranged, and described reagent needle arm 94 is positioned at reagent pin 93 and is arranged over bearing pin fixed plate 97, described bearing pin 95 Upper end is fixed in bearing pin fixed plate 97, and set 96 is protected through reagent pin in lower end, and is slidably connected with reagent pin protection set 96.Institute Stating rotating mechanism can make reagent pin 93 freely rotate between reagent disc and reaction tray, and described elevating mechanism facilitates reagent pin to carry Take reagent or reagent adding;The setting of described buffer gear can ensure that reagent pin 93 produces minimum in the case of being clashed into Infringement, effectively protect.
In the present embodiment, the connection of described reagent pin 93 upper end is provided with reagent needle adapter 98.
In the present embodiment, the outside of described reagent pin 93 upper end is provided with the reagent pin guide pin bushing being coaxially disposed with reagent pin 93 99.Arranging of described reagent pin guide pin bushing 99 can be effectively ensured the motion of reagent pin 93 in the vertical direction.
In the present embodiment, described reagent needle arm 94 is provided with charge sensors 910, and described reagent pin protection set 96 is provided with Sensing catch 911, described sensing catch 911 and charge sensors 910 cooperate setting.Described sensing catch 911 and charging Arranging of sensor 910 can monitor whether reagent pin 93 is clashed in real time.
In the present embodiment, described rotating mechanism includes ball spline pair 912, electric rotating machine 913, electric rotating machine mounting base 914 and the 3rd driving device, described ball spline pair 912 upper end is connected with reagent needle arm 94, and lower end is from top to down through rotation Rotating motor mounting base 914, described electric rotating machine 913 drives ball spline pair 912 to rotate by the 3rd driving device, and then band Dynamic reagent needle assembly rotates around ball spline pair 912.
In the present embodiment, described 3rd driving device includes the 3rd driving pulley the 915, the 3rd driven pulley 916 and the 3rd Timing Belt 917, described 3rd driving pulley 915 is located at the outfan of electric rotating machine 913, and the 3rd driven pulley 916 is set in rolling Outside spline pair 912, the 3rd driven pulley 916 is connected with the 3rd driving pulley 915 by the 3rd Timing Belt 917.
In the present embodiment, described elevating mechanism includes upper and lower motor 918, reagent pin slide rail 920 and the 4th driving device, institute Stating upper and lower motor 918 to be fixed on reagent pin base plate 91 by needle stand side plate 921, whirler is vertically located at by reagent pin slide rail 920 On structure mounting base 92, described ball spline pair 912 lower end is slidably connected with reagent pin slide rail 920, when upper by installing plate 922 Lower motor 918 drives installing plate 922 to move up and down along reagent pin slide rail 920 by the 4th driving device, and then drives reagent Needle assembly moves up and down.
In the present embodiment, described 4th driving device includes the 4th driving pulley the 923, the 4th driven pulley 924 and the 4th Timing Belt 925, the 4th driving pulley 923 is located at the outfan of upper and lower motor 918, and the 4th driven pulley 924 is driven by the 4th Band wheel seat 926 is located on needle stand side plate 921, and the 4th driven pulley 924 is by the 4th Timing Belt 925 and the 4th driving pulley 923 Being connected, be equipped with reagent pin slide block 927 with described reagent pin slide rail 920, described reagent pin slide block 927 1 aspect is passed through Belt fixture block 928 is connected with installing plate 922, is on the other hand connected with the 4th Timing Belt 925.
In the present embodiment, between described ball spline pair 912 and installing plate 922, it is provided with ball bearing 929.

Claims (30)

1. a full-automatic illumination immunity analysis instrument, it is characterised in that include shell, support body, sample introduction frame, reaction cup storehouse, reaction Dish, reagent disc, sample-adding module, reagent adding module, liquid circuit module, detection module and control module, described reaction cup storehouse, reaction Dish, reagent disc, sample-adding module, reagent adding module are all located on support body, and described shell is covered in outside described support body, described reaction Dish includes that the first reaction tray and the second reaction tray, described first reaction tray side are positioned at below described reaction cup storehouse, described reaction Dish, reagent disc, sample-adding module are all connected with liquid circuit module with reagent adding module, described sample introduction frame, reaction cup storehouse, reaction tray, Reagent disc, sample-adding module, reagent adding module, liquid circuit module, detection module all electrically connect with control module.
2. full-automatic illumination immunity analysis instrument as claimed in claim 1, it is characterised in that described reaction cup storehouse includes double-pole Device, the first base plate, first fix axle, the first motor, reaction cup pipe, reaction cup, reaction top rotary table and reaction lower rotary table, described First lower end fixing axle is fixed on described first base plate, and described reaction top rotary table and reaction lower rotary table are set with in described First top and bottom fixing axle, and around the first solid fixed-axis rotation, institute under the drive of the first motor and the first pulley arrangement Stating reaction cup superposition and be located at inside reaction cup pipe, the top and bottom of described reaction cup pipe are installed on reaction top rotary table respectively with anti- Answering on lower rotary table, described double-pole device is fixed on described first base plate by support means, and double-pole device is positioned at described Above reaction top rotary table, and it is positioned at directly over reaction cup pipe.
3. full-automatic illumination immunity analysis instrument as claimed in claim 2, it is characterised in that described double-pole device includes two Double-pole motor, two screw mandrels, double-pole bearing, two double-pole guide rails and two pieces of double-pole slide blocks, described support means bag Including support and gripper shoe, described gripper shoe is fixed on described first base plate by support, described double-pole bearing and two pairs Push rod motor is parallel to each other on the surface being fixed on described gripper shoe, and two double-pole guide rails are vertical and parallel are fixed on Double Tops On rod bearing, two pieces of double-pole slide blocks are connected with two double-pole slide respectively, and two screw mandrel lower ends are double with two respectively Push rod motor helical connects, and upper end is connected with two pieces of double-pole slide blocks respectively.
4. full-automatic illumination immunity analysis instrument as claimed in claim 2, it is characterised in that described reaction cup pipe includes two phases The most parallel cavity, reaction cup superposition puts into two cavitys, and the lower end of reaction cup pipe is provided with shell fragment around two cavitys.
5. full-automatic illumination immunity analysis instrument as claimed in claim 4, it is characterised in that the neighboring of described reaction top rotary table Being provided with a circle reaction cup pipe clamp groove, be provided with reaction tube intermediate plate in each reaction cup pipe clamp groove, described reaction lower rotary table is provided with The through hole that one circle is corresponding with described reaction cup pipe clamp groove, the quantity of described through hole is the twice of reaction cup pipe clamp groove, and two lead to Hole is for a reaction cup pipe clamp groove, and the upper end of reaction cup pipe snaps in described reaction tube intermediate plate, and lower end is inserted in two through holes.
6. full-automatic illumination immunity analysis instrument as claimed in claim 2, it is characterised in that described first to fix axle outside sheathed Having the first axle sleeve, described first axle sleeve and first to fix and be provided with two clutch shaft bearings between axle, described first pulley arrangement includes First big belt wheel, the first small pulley and the first belt, described first small pulley is fixed on the outfan of described first motor, institute State the first big belt wheel and be installed on the lower end of described first axle sleeve, by the first belt, the first big belt wheel and the first small pulley are connected Connect.
7. full-automatic illumination immunity analysis instrument as claimed in claim 1, it is characterised in that described first reaction tray and second anti- Should coil and be mounted on reaction tray mounting base, described first reaction tray includes the first disk body, the first disk cover, the first rotating disk and One driving device, described first rotating disk is located in the first disk body, and the first disk cover is covered in the first disk body top, and is positioned at first turn Above dish, the first rotating disk rotates under the drive of the first driving device;Second reaction tray include the second disk body, the second disk cover, Two rotating disks and the second driving device, described second rotating disk is located in the second disk body, and the second disk cover is covered in the second disk body top, and Being positioned at above the second rotating disk, the second rotating disk rotates under the drive of the second driving device.
8. full-automatic illumination immunity analysis instrument as claimed in claim 7, it is characterised in that position, side in described first reaction tray Below reaction cup storehouse, the reaction cup in described reaction cup storehouse is loaded into downwards on the first rotating disk, and described first disk cover is positioned at Below reaction warehouse, place is provided with arc notch, and described first disk cover is provided with the first reagent adding hole, reagent dilutions hole, well and adds Sample dilution holes.
9. full-automatic illumination immunity analysis instrument as claimed in claim 7, it is characterised in that described second reaction tray is provided with the One cleans device and second cleans device, and described second disk cover is provided with first and washes plate hole and second and wash plate hole, described first clear Cleaning device includes that first washes plate module, the first lifting module and the first blocking mechanism, and described first washes plate module is located at first liter Fall module top, and be positioned at first and wash above plate hole, described first blocking mechanism is located at first and is washed plate module side;Described second Cleaning device and include the second cleaning module and the second lifting module, described second cleaning module is located at the second lifting module top, And be positioned at second and wash above plate hole;Described first blocking mechanism includes the first positioning plate, some first direct current generators, Ruo Gan One guide shaft and some first link gears, it is fixed that described first guide shaft one end is set in parallel in described first by the first guide shaft support On the plate upper surface of position, the other end and the first link gear are connected, the outfan of described first direct current generator and described first Link gear is connected, and then drives the first guide shaft to move along a straight line along the first guide shaft support.
10. full-automatic illumination immunity analysis instrument as claimed in claim 9, it is characterised in that described first link gear includes the One connecting rod and the first cam, described first cam is located at the outfan of described first direct current generator, described head rod One end is connected with the first cam rotation, and the other end is rotationally connected with described first guide shaft, and by guide shaft alignment pin diametrically Fixing.
11. full-automatic illumination immunity analysis instruments as claimed in claim 10, it is characterised in that the lower end of described guide shaft alignment pin Being provided with sensing catch, position corresponding with described sensing catch on described first positioning plate is provided with optocoupler sensor.
12. full-automatic illumination immunity analysis instruments as claimed in claim 7, it is characterised in that be additionally provided with in described second reaction tray PMT light-metering assembly, is positioned at below described second reaction tray and just to described PMT light-metering assembly and is provided with push rod component, described top Bar assembly includes push rod base plate, DC stepper motor, push rod and push rod slide mechanism, and described DC stepper motor is located at described top On bar base plate lower surface, and the outfan of DC stepper motor is provided with push rod leading screw, and described push rod silk is located at by described push rod The upper end of thick stick, and be slidably connected with push rod slide mechanism by push rod connecting plate, described push rod upper end is through described second reaction Reaction cup is pushed described PMT light-metering assembly and detects by dish.
13. full-automatic illumination immunity analysis instruments as claimed in claim 12, it is characterised in that described push rod slide mechanism includes Line slide rail and slide block, the upper surface of described push rod base plate is provided with slide rail mounting seat, and described line slide rail is vertically arranged, described Slide block side is slidably connected with described line slide rail, and opposite side is connected with push rod connecting plate.
14. full-automatic illumination immunity analysis instruments as claimed in claim 9, it is characterised in that be positioned at described on described second disk cover First washes plate hole side is provided with the second reagent adding hole, described second disk cover is positioned at described second and washes plate hole side and be provided with and add substrate Hole.
15. full-automatic illumination immunity analysis instruments as claimed in claim 9, it is characterised in that described first lifting module and second Lifting modular structure is identical, all includes lifting motor, motor mounting plate, elevating screw and vertical sliding panel, described lifting motor It is fixed on motor mounting plate, the upper surface of motor mounting plate is provided with guide rail vertical plate, on described guide rail vertical plate vertically Being provided with guide rail, described vertical sliding panel is connected by slide with described guide rail vertical plate, the lower end of described elevating screw with The outfan of described lifting motor is connected, and upper end is connected with described vertical sliding panel by feed screw nut.
16. full-automatic illumination immunity analysis instruments as claimed in claim 15, it is characterised in that described first washes plate module includes First cleaning needle base plate, some first pins fix seat, some first injection needle and some first aspirating needles, described vertical sliding panel Upper end is provided with the first cleaning support location-plate, and described first cleaning needle base plate is fixed on described first clear by the first locking nut Washing on support location-plate, described first injection needle and the first aspirating needle fix seat and described first cleaning needle base plate by the first pin Being slidably connected, described first pin is fixed seat lower surface and is provided with oilless bushing, and described oilless bushing inserts described first cleaning needle In base plate, described first pin is fixed and is provided with spring also by spring lead on seat, and described spring housing is located on spring lead; Second cleaning module includes that the second cleaning needle base plate, some second pins fix seat, some second injection needle, some second aspirating needles With substrate pin, described vertical sliding panel upper end is provided with the second cleaning support location-plate, and described second cleaning needle base plate passes through second Locking nut is fixed on described second and cleans on support location-plate, and described second injection needle, the second aspirating needle and substrate pin pass through Second pin is fixed seat and is slidably connected with described second cleaning needle base plate.
17. full-automatic illumination immunity analysis instruments as claimed in claim 1, it is characterised in that described reagent disc bag reagent pot, examination Agent rotating disk and the second pulley arrangement, described reagent rotor is located at inside described reagent pot, and the center of described reagent rotor is provided with Second fixes axle, and the described second lower end fixing axle is connected with described second pulley arrangement, in the drive of the second pulley arrangement Under described reagent rotor around the second solid fixed-axis rotation, described reagent rotor upper surface be provided with some in divergent shape the reagent of distribution Bottle, the upper end of described reagent pot is provided with reagent disk cover.
18. full-automatic illumination immunity analysis instruments as claimed in claim 17, it is characterised in that described reagent disc also includes ventilating System, described ventilating system includes dehumidify fan and air channel, and described dehumidifying fan is located on the upper surface of reagent rotor, described wind One end, road is positioned at below reagent rotor, and the other end extends outside reagent pot outward flange.
19. full-automatic illumination immunity analysis instruments as claimed in claim 18, it is characterised in that described reagent disc also includes bar code Machine, the sidewall of described reagent pot is provided with scanning mouth, and described barcode machine is positioned at outside described scanning mouth, the scanning examination of described barcode machine Bar code on agent bottle.
20. full-automatic illumination immunity analysis instruments as claimed in claim 1, it is characterised in that described sample introduction frame includes housing, props up Frame, injector handgrip and some sample racks, the arrangement of described sample rack is located on support, and each sample rack is placed several examinations Pipe, described support has been horizontally disposed with injector slide rail, and described injector handgrip slides and is located on described injector slide rail, described Being additionally provided with horizontal sliding motor on support, described horizontal sliding motor drives described injector handgrip entering by handgrip Timing Belt On sample device slide rail, level is slided, and on described support, also level is slided and is provided with sample-adding position, and described housing is provided with at opposite position Well.
21. full-automatic illumination immunity analysis instruments as claimed in claim 20, it is characterised in that described sample-adding position includes being loaded position Slide rail, sample-adding position motor and some pallets, described pallet is provided with sample rack, described sample-adding position slide rail level and and injector Slide rail is parallel to each other and is located at injector slide rail rear, and described pallet is slided with described sample-adding position slide rail by sample-adding position slide mechanism Connecting, described sample-adding position motor drives pallet to slide along sample-adding position slide rail by sample-adding bit synchronization band.
22. full-automatic illumination immunity analysis instruments as claimed in claim 21, it is characterised in that described sample-adding position slide mechanism bag Including sample-adding position slide block and sample-adding position take-up housing, described sample-adding position slide block is slidably connected with described sample-adding position slide rail, described sample-adding position Take-up housing is located at above the slide block of described sample-adding position, and described pallet is located at above the take-up housing of described sample-adding position.
23. full-automatic illumination immunity analysis instruments as claimed in claim 22, it is characterised in that described sample-adding position includes two torr Dish, two pallets are connected by connecting seat.
24. full-automatic illumination immunity analysis instruments as claimed in claim 1, it is characterised in that described reagent adding module includes reagent Needle assembly, rotating mechanism and elevating mechanism, described elevating mechanism is installed on support body by reagent pin base plate, described rotating mechanism Be fixed on elevating mechanism top by rotating mechanism mounting base, described reagent needle assembly respectively with rotating mechanism and elevating mechanism It is connected.
25. full-automatic illumination immunity analysis instruments as claimed in claim 24, it is characterised in that described reagent needle assembly includes examination Agent pin and reagent needle arm, the syringe needle of described reagent pin is vertically arranged downwards, and upper end is by reagent pin protection set and described reagent pin Arm slides and arranges, and described reagent needle arm is positioned at reagent pin and is arranged over bearing pin fixed plate, and described bearing pin fixed plate is provided with pin Axle, the lower end of described bearing pin is through reagent pin protection set, and is slidably connected with reagent pin protection set, and described reagent pin upper end connects It is provided with reagent needle adapter.
26. full-automatic illumination immunity analysis instruments as claimed in claim 25, it is characterised in that the outside of described reagent pin upper end It is provided with the reagent pin guide pin bushing arranged with reagent coaxial needle.
27. full-automatic illumination immunity analysis instruments as claimed in claim 24, it is characterised in that described rotating mechanism includes ball Spline pair, electric rotating machine, electric rotating machine mounting base and the 3rd driving device, described ball spline pair upper end and reagent needle arm phase Connecting, lower end is from top to down through electric rotating machine mounting base, and described electric rotating machine drives ball flower by the 3rd driving device Key pair rotates, and then drives reagent needle assembly to rotate around ball spline pair.
28. full-automatic illumination immunity analysis instruments as claimed in claim 27, it is characterised in that described 3rd driving device includes 3rd driving pulley, the 3rd driven pulley and the 3rd Timing Belt, described 3rd driving pulley is located at the outfan of electric rotating machine, and Three driven pulleys are set in outside ball spline pair, and the 3rd driven pulley is connected by the 3rd Timing Belt and the 3rd driving pulley Connect.
29. full-automatic illumination immunity analysis instruments as claimed in claim 28, it is characterised in that described elevating mechanism includes up and down Motor, reagent pin slide rail and the 4th driving device, described upper and lower motor is fixed on reagent pin base plate by needle stand side plate, reagent Pin slide rail is vertically located on rotating mechanism mounting base, is slided with reagent pin slide rail by installing plate in described ball spline pair lower end Connect, when upper and lower motor drives installing plate to move up and down along reagent pin slide rail by the 4th driving device, and then drive reagent Needle assembly moves up and down.
30. full-automatic illumination immunity analysis instruments as claimed in claim 29, it is characterised in that described 4th driving device includes 4th driving pulley, the 4th driven pulley and the 4th Timing Belt, the 4th driving pulley is located at the outfan of upper and lower motor, the 4th from Movable belt pulley is located on needle stand side plate by the 4th driven belt wheel seat, and the 4th driven pulley passes through the 4th Timing Belt and the 4th main belt Wheel is connected, and is equipped with reagent pin slide block with described reagent pin slide rail, and described reagent pin slide block is on the one hand by the second skin Band fixture block is connected with installing plate, is on the other hand connected with the 4th Timing Belt.
CN201620707276.8U 2016-06-30 2016-06-30 A kind of full-automatic illumination immunity analysis instrument Withdrawn - After Issue CN205844341U (en)

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105929184A (en) * 2016-06-30 2016-09-07 嘉兴凯实生物科技有限公司 Full-automatic luminescence immunity analyzer
CN107192841A (en) * 2017-06-27 2017-09-22 苏州长光华医生物医学工程有限公司 One kind can drawing liquid manipulator
CN109387646A (en) * 2018-12-08 2019-02-26 安图实验仪器(郑州)有限公司 Chemical illumination immunity analysis instrument
CN109444450A (en) * 2018-12-27 2019-03-08 厦门先明生物技术有限公司 A kind of whole blood sample automatic sampling apparatus
CN109580594A (en) * 2017-09-29 2019-04-05 深圳市新产业生物医学工程股份有限公司 Chemiluminescence detector incubates device and reaction disc mechanism
CN110763854A (en) * 2019-11-30 2020-02-07 宁波普瑞柏生物技术股份有限公司 Sample introduction module
CN111094991A (en) * 2017-08-16 2020-05-01 北京普利生仪器有限公司 Blood analyzer and control method thereof
CN113335930A (en) * 2021-06-15 2021-09-03 重庆中元汇吉生物技术有限公司 Recovery device for reaction vessel

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105929184A (en) * 2016-06-30 2016-09-07 嘉兴凯实生物科技有限公司 Full-automatic luminescence immunity analyzer
CN105929184B (en) * 2016-06-30 2018-05-15 嘉兴凯实生物科技有限公司 A kind of full-automatic illumination immunity analysis instrument
CN107192841A (en) * 2017-06-27 2017-09-22 苏州长光华医生物医学工程有限公司 One kind can drawing liquid manipulator
CN107192841B (en) * 2017-06-27 2018-04-20 苏州长光华医生物医学工程有限公司 One kind can drawing liquid manipulator
CN111094991A (en) * 2017-08-16 2020-05-01 北京普利生仪器有限公司 Blood analyzer and control method thereof
CN109580594A (en) * 2017-09-29 2019-04-05 深圳市新产业生物医学工程股份有限公司 Chemiluminescence detector incubates device and reaction disc mechanism
CN109580594B (en) * 2017-09-29 2024-04-02 深圳市新产业生物医学工程股份有限公司 Chemiluminescent detector, incubation device and reaction disk mechanism
CN109387646A (en) * 2018-12-08 2019-02-26 安图实验仪器(郑州)有限公司 Chemical illumination immunity analysis instrument
CN109387646B (en) * 2018-12-08 2024-02-09 安图实验仪器(郑州)有限公司 Chemiluminescent immunoassay analyzer
CN109444450A (en) * 2018-12-27 2019-03-08 厦门先明生物技术有限公司 A kind of whole blood sample automatic sampling apparatus
CN109444450B (en) * 2018-12-27 2022-05-17 厦门先明生物技术有限公司 Whole blood sample autoinjection device
CN110763854A (en) * 2019-11-30 2020-02-07 宁波普瑞柏生物技术股份有限公司 Sample introduction module
CN113335930A (en) * 2021-06-15 2021-09-03 重庆中元汇吉生物技术有限公司 Recovery device for reaction vessel
WO2022262726A1 (en) * 2021-06-15 2022-12-22 中元汇吉生物技术股份有限公司 Recovery device for reaction container

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