CN205484359U - Card formula colloidal gold antibody detection device - Google Patents
Card formula colloidal gold antibody detection device Download PDFInfo
- Publication number
- CN205484359U CN205484359U CN201620204239.5U CN201620204239U CN205484359U CN 205484359 U CN205484359 U CN 205484359U CN 201620204239 U CN201620204239 U CN 201620204239U CN 205484359 U CN205484359 U CN 205484359U
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- test paper
- support
- detection device
- colloidal gold
- cassette
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Abstract
The utility model belongs to the biological detection field, concretely relates to card formula colloidal gold antibody detection device. Detection device includes shell and test paper, and the shell comprises go to the bottom C and upper cover A, goes to the bottom to the cabin structure, and its front end is the cabin body 7, and the rear end is hull 8, the cabin body is solid structure, has the 20 intercommunication external world and the hulls of hydrophilic runner of a horizontal direction among them, the upper cover closely agrees with the formation cavity with the hull of the rear end of going to the bottom, and test paper B is located this cavity, and test paper's one end and hydrophilic runner link up, and the sample takes place the reaction on hydrophilic runner flows test paper, on cover and be provided with observation window 22 and be used for observing the testing result. The utility model discloses designed hydrophilic runner on the shell is gone to the bottom, the sample can not spread in hydrophilic runner everywhere, but on flowing test paper with continuous route from hydrophilic runner, the utility model discloses need not extra quantitative application of sample device, thereby reach the purpose of quantitative application of sample through the design control application of sample volume to the runner volume.
Description
Technical field
This utility model belongs to field of biological detection, is specifically related to a kind of cassette colloidal gold antibody detection device.
Background technology
Immune colloid gold quick diagnosis technology is built upon in elisa, latex agglutination test, monoclonal antibody technique and immuno-gold labeling technical foundation, with gold colloidal as label, utilize special antigen antibody reaction iodine signal, by directly observing it is determined that the new technique of result.This technology has the advantages such as simple, quick, accurate and pollution-free, develops rapidly at many diagnostic fields such as clinical medicine detection, animal medicine detection, hormone test, food safety detection, drug residue and drugs quickly detections.
The commercial kit using colloidal gold method detection antibody on Vehicles Collected from Market has a lot, and its packaged form mainly has bar formula and cassette two kinds, and bar formula is naked bar; shell is not had to protect; it is easily damaged Test paper, it is not easy to preserve, be only applicable to professional institution's large-scale experiment.Cassette for there being outer cover packaging, effect protected to reagent paper, shell has well and observation window.Test paper is all made up of sample pad, label pad, coated film (draw on it and have detection line, nature controlling line) and absorption pad.But, the problem that current cassette colloidal gold antibody detection kit exists sampling inconvenience.Need to use the Special experimental equipment such as pipettor during existing common cassette colloidal gold strip sample-adding, it is impossible to direct sample；And the colloidal gold strip of the energy direct sample that some is special the most all uses the structure of two-piece unit on market, not only there will be the problems such as pressure shell dislocation, deformation when producing, thus cause manufacturing scrap rate high, and it also there will be when application, and suction sample is difficult and upper and lower junction sepage etc. the problem that gets stuck, being normally carried out of impact experiment.
Summary of the invention
This utility model is for the deficiencies in the prior art, it is therefore intended that provide a kind of cassette colloidal gold antibody detection device.
The technical scheme that this utility model is used is:
A kind of cassette colloidal gold antibody detection device, including shell and Test paper, described Test paper is positioned at shell, it is characterised in that: described shell is made up of the C and upper cover A that goes to the bottom, and goes to the bottom as cabin structure, and its front end is nacelle 7, and rear end is hull 8；Described nacelle is entity structure, has the hydrophilic runner 20 of a horizontal direction to connect the external world and hull in the middle of it；Upper cover closely agrees with formation cavity with the hull of rear end of going to the bottom, and Test paper B is positioned at this cavity, and one end of described Test paper is connected with hydrophilic runner, and sample flows to react on Test paper through hydrophilic runner；Cover on described and be provided with observation window 22 for observing testing result.
By such scheme, described Test paper is by base plate 1 and mutually closely overlaps hemofiltration pad 2, reaction film 3 and the absorption pad 4 being pasted onto on base plate and forms, antigen or the antibody of colloid gold label it is embedded with on described hemofiltration pad, detection T line 5 and Quality Control C line 6 it is fixed with on described reaction film, it is coated with antigen or antibody on described detection T line, described Quality Control C line is coated with two and resists.
By such scheme, the hemofiltration pad end of described Test paper is connected with hydrophilic runner, and described hemofiltration pad end is cut into V-structure.
By such scheme, described in the go to the bottom hull of rear end include supporting the supporting structure of Test paper, described supporting structure includes trapezoidal horizontal support, the horizontal support of strip and the fixed support of horizontal support both sides.
By such scheme, the described support in order to support hemofiltration pad includes trapezoidal horizontal support 9, the horizontal support of strip 10,11 and the fixed support 12 of both sides thereof, include horizontal support 13,14 and both sides fixed support 15 thereof in order to support the support of reaction film, include horizontal support 16,17 and both sides fixed support 18 thereof in order to support the support of absorption pad.
By such scheme, described fixed support is provided with fixing groove 19, described on cover and be provided with protruding 21, fixing groove closely agrees with projection.
By such scheme, described base plate is PVC base plate, and the one side of described PVC base plate is double faced adhesive tape.
By such scheme, described reaction film is nitrocellulose filter, and described absorption pad is absorbent paper.
The assemble method of cassette colloidal gold antibody described in the utility model detection device: Test paper is kept flat in the hull that shell is gone to the bottom, hemofiltration pad end is placed on trapezoid support, the hemofiltration pad V-type summit of Test paper is connected to hydrophilic runner mutually with the level gone to the bottom in nacelle, the Test paper being dried has bigger capillarity than hydrophilic runner, thus cause all samples in hydrophilic runner to move on the hemofiltration pad of Test paper, flow to further along react on reaction film, eventually flow on adsorptive pads；Cover outer casing upper cover, make upper cover and the hull gone to the bottom closely fit together thus form cavity.
Cassette colloidal gold antibody described in the utility model detection device using method: utilize device go to the bottom arrange hydrophilic runner sampling, whole blood to be checked/plasma/serum sample is drawn by capillary action by the hydrophilic runner of horizontal direction, flow on the hemofiltration pad of Test paper with continuous print path, erythrocyte can be separated from blood plasma by hemofiltration pad, reacts and show result after blood plasma continuation flow forward to reaction film；Especially, when detection need to add quantitative sample, the structure design of this detection device makes detection become simpler, it is not necessary to extra quantitative sample adding device (such as capillary tube, sample injector etc.), by the design of hydrophilic runner volume is controlled sample-adding amount, thus can reach to add the purpose of quantitative sample.
The beneficial effects of the utility model: existing cassette colloidal gold antibody detection device is improved by this utility model, hydrophilic runner it is provided with on shell is gone to the bottom, and hydrophilic runner is an integral passage, sample will not be to bleeding around in hydrophilic runner, sample so can be made to flow to Test paper from hydrophilic runner with continuous print path, owing to dry Test paper has bigger capillarity than hydrophilic runner, such that it is able to make all samples in hydrophilic runner move on the hemofiltration pad of Test paper；Test paper of the present utility model eliminates sample pad, has both decreased operation, has saved again cost；In this utility model, the design of hydrophilic runner makes the detection by quantitative of sample become simpler, it is not necessary to extra quantitative sample adding device (such as capillary tube, sample injector etc.), by the design of runner volume can control sample-adding amount, thus arrives the purpose adding quantitative sample.
Accompanying drawing explanation
Fig. 1 is the overall structure schematic diagram of this utility model cassette colloidal gold antibody detection device, and wherein A is upper cover, and B is Test paper, and C is for going to the bottom.
Fig. 2 is the structural representation of Test paper, and wherein 1 is base plate, and 2 is hemofiltration pad, and 3 is reaction film, and 4 is absorption pad, and 5 is detection T line, and 6 is Quality Control C line.
Fig. 3 is the structural representation gone to the bottom, and wherein 7 is nacelle, and 8 is hull, and 9 is trapezoidal horizontal support, and 10,11,13,14,16,17 is the horizontal support of strip, and 12,15,18 is both sides fixed support, and 19 is fixing groove.
Fig. 4 is the cross sectional figure of nacelle 7 of going to the bottom, and wherein 20 is hydrophilic runner.
Fig. 5 is the structural representation of upper cover, and wherein 21 is protruding, and 22 is observation window.
Detailed description of the invention
In order to be more fully understood that this utility model, it is further elucidated with content of the present utility model below in conjunction with embodiment, but content of the present utility model is not limited solely to example below.
Embodiment
1
As shown in drawings, a kind of cassette colloidal gold antibody detection device, including shell and Test paper, described Test paper is positioned at shell, and described shell is made up of the C and upper cover A that goes to the bottom, and goes to the bottom as cabin structure, and its front end is nacelle 7, and rear end is hull 8；Described nacelle is entity structure, has the hydrophilic runner 20 of a horizontal direction to connect the external world and hull in the middle of it；Upper cover closely agrees with formation cavity with the hull of rear end of going to the bottom, and Test paper B is positioned at this cavity.
Above-mentioned Test paper is by base plate 1 and mutually closely overlaps hemofiltration pad 2, reaction film 3 and the absorption pad 4 being pasted onto on base plate and forms, antigen or the antibody of colloid gold label it is embedded with on described hemofiltration pad, detection T line 5 and Quality Control C line 6 it is fixed with on described reaction film, it is coated with antigen or antibody on described detection T line, described Quality Control C line is coated with two and resists.The hemofiltration pad end of described Test paper is connected with hydrophilic runner, and described hemofiltration pad end is cut into V-structure, and sample flows to react on Test paper through hydrophilic runner.Described base plate is PVC base plate, and the one side of described PVC base plate is double faced adhesive tape；Described reaction film is nitrocellulose filter, and described absorption pad is absorbent paper.
The hull of above-mentioned rear end of going to the bottom includes the supporting structure supporting Test paper, and described supporting structure includes trapezoidal horizontal support, the horizontal support of strip and the fixed support of horizontal support both sides；Trapezoidal horizontal support 9, the horizontal support of strip 10,11 and the fixed support 12 of both sides thereof is included in order to support the support of hemofiltration pad, include horizontal support 13,14 and both sides fixed support 15 thereof in order to support the support of reaction film, include horizontal support 16,17 and both sides fixed support 18 thereof in order to support the support of absorption pad.Be provided with fixing groove 19 on described fixed support, described on cover and be provided with protruding 21, fixing groove closely agrees with projection.Cover on described and be provided with observation window 22 for observing testing result.
The assemble method of cassette colloidal gold antibody described in the utility model detection device: Test paper is kept flat in the hull that shell is gone to the bottom, hemofiltration pad end is placed on trapezoid support, the hemofiltration pad V-type summit runner hydrophilic with the horizontal direction gone to the bottom in nacelle of Test paper is connected mutually, the Test paper being dried has bigger capillarity than hydrophilic runner, thus cause all samples in hydrophilic runner to move on the hemofiltration pad of Test paper, flow to further along react on reaction film, eventually flow on adsorptive pads；Cover outer casing upper cover, make upper cover and the hull gone to the bottom closely fit together thus form cavity.
Cassette colloidal gold antibody described in the utility model detection device using method: utilize device go to the bottom arrange hydrophilic runner sampling, whole blood to be checked/plasma/serum sample is drawn by capillary action by the hydrophilic runner of horizontal direction, flow on the hemofiltration pad of Test paper with continuous print path, erythrocyte can be separated from blood plasma by hemofiltration pad, reacts and show result after blood plasma continuation flow forward to reaction film；Especially, when need to add quantitative sample when detection, the structure design of this detection device makes detection become simpler, it is not necessary to extra quantitative sample adding device (such as capillary tube, sample injector etc.), by the design of hydrophilic runner volume being controlled sample-adding amount, thus arrive the purpose adding quantitative sample.
Obviously, above-described embodiment is only by clearly demonstrating made example, and not restriction to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here without also cannot all of embodiment be given exhaustive.And within the protection domain that the obvious change therefore amplified or variation are created still in this utility model.
Claims (8)
1. a cassette colloidal gold antibody detection device, including shell and Test paper, described Test paper is positioned at shell, it is characterized in that: described shell is by going to the bottom (C) and upper cover (A) forms, go to the bottom as cabin structure, its front end is nacelle (7), and rear end is hull (8)；Described nacelle is entity structure, has hydrophilic runner (20) the connection external world and the hull of a horizontal direction in the middle of it；Upper cover closely agrees with formation cavity with the hull of rear end of going to the bottom, and Test paper (B) is positioned at this cavity, and one end of described Test paper is connected with hydrophilic runner, and sample flows to react on Test paper through hydrophilic runner；Cover on described and be provided with observation window (22) and be used for observing testing result.
Cassette colloidal gold antibody the most according to claim 1 detection device, it is characterized in that, described Test paper is by base plate (1) and mutually closely overlaps hemofiltration pad (2), reaction film (3) and the absorption pad (4) being pasted onto on base plate and forms, antigen or the antibody of colloid gold label it is embedded with on described hemofiltration pad, detection T line (5) and Quality Control C line (6) it is fixed with on described reaction film, it is coated with antigen or antibody on described detection T line, described Quality Control C line is coated with two and resists.
Cassette colloidal gold antibody the most according to claim 2 detection device, it is characterised in that the hemofiltration pad end of described Test paper is connected with hydrophilic runner, and described hemofiltration pad end is cut into V-structure.
Cassette colloidal gold antibody the most according to claim 2 detection device, it is characterized in that, the hull of described rear end of going to the bottom includes the supporting structure supporting Test paper, and described supporting structure includes trapezoidal horizontal support, the horizontal support of strip and the fixed support of horizontal support both sides.
Cassette colloidal gold antibody the most according to claim 4 detection device, it is characterized in that, trapezoidal horizontal support (9), the horizontal support of strip (10,11) and the fixed support (12) of both sides thereof is included in order to support the support of hemofiltration pad, include horizontal support (13,14) and both sides fixed support (15) thereof in order to support the support of reaction film, include horizontal support (16,17) and both sides fixed support (18) thereof in order to support the support of absorption pad.
Cassette colloidal gold antibody the most according to claim 4 detection device, it is characterised in that be provided with fixing groove (19) on described fixed support, described on cover and be provided with projection (21), fixing groove closely agrees with projection.
Cassette colloidal gold antibody the most according to claim 2 detection device, it is characterised in that described base plate is PVC base plate, and the one side of described PVC base plate is double faced adhesive tape.
Cassette colloidal gold antibody the most according to claim 2 detection device, it is characterised in that described reaction film is nitrocellulose filter, and described absorption pad is absorbent paper.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620204239.5U CN205484359U (en) | 2016-03-15 | 2016-03-15 | Card formula colloidal gold antibody detection device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201620204239.5U CN205484359U (en) | 2016-03-15 | 2016-03-15 | Card formula colloidal gold antibody detection device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205484359U true CN205484359U (en) | 2016-08-17 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201620204239.5U Expired - Fee Related CN205484359U (en) | 2016-03-15 | 2016-03-15 | Card formula colloidal gold antibody detection device |
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| CN (1) | CN205484359U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109085159A (en) * | 2017-08-21 | 2018-12-25 | 上海荒岛科技有限公司 | A kind of substrate and detection card |
| CN111735811A (en) * | 2020-08-12 | 2020-10-02 | 民康医疗科技（天津）有限公司 | Triglyceride detection reagent, triglyceride detection test paper and preparation method of triglyceride detection test paper |
| CN113341136A (en) * | 2020-03-01 | 2021-09-03 | 上海雄图生物科技有限公司 | Detection method for rapidly screening novel coronavirus |
-
2016
- 2016-03-15 CN CN201620204239.5U patent/CN205484359U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109085159A (en) * | 2017-08-21 | 2018-12-25 | 上海荒岛科技有限公司 | A kind of substrate and detection card |
| CN113341136A (en) * | 2020-03-01 | 2021-09-03 | 上海雄图生物科技有限公司 | Detection method for rapidly screening novel coronavirus |
| CN111735811A (en) * | 2020-08-12 | 2020-10-02 | 民康医疗科技（天津）有限公司 | Triglyceride detection reagent, triglyceride detection test paper and preparation method of triglyceride detection test paper |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160817 Termination date: 20210315 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |