CN205443145U - Liquaemin removes look jar - Google Patents
Liquaemin removes look jar Download PDFInfo
- Publication number
- CN205443145U CN205443145U CN201520823872.8U CN201520823872U CN205443145U CN 205443145 U CN205443145 U CN 205443145U CN 201520823872 U CN201520823872 U CN 201520823872U CN 205443145 U CN205443145 U CN 205443145U
- Authority
- CN
- China
- Prior art keywords
- tank
- dissolving tank
- separatory
- agitating unit
- agitating device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model relates to a liquaemin removes look jar, including dissolving tank and the branch fluid reservoir that communicates from top to bottom, a switching valve has between dissolving tank and the branch fluid reservoir, the dissolving tank upper end has acid -base regulation hole A and pan feeding mouth A, has an agitating unit A inside it, agitating unit is including fixing motor on the dissolving tank up end, connect the (mixing) shaft on the motor and lieing in the epaxial stirring tooth of stirring, and the lower extreme of this dissolving tank has a screen cloth, divide the fluid reservoir upper end to have an acid -base regulation hole B and a pan feeding mouth B, have an agitating unit B inside it, agitating unit B is the same with the agitating unit A structure, has an accuse winchester disk pipe on this minute fluid reservoir lateral wall. The utility model has the advantages of: integrate each process in an equipment, the actual operation of being convenient for adapts to large batch production, will not make a round trip to rotate by solution between the container.
Description
Technical field
This utility model relates to a kind of heparin sodium preparation field, particularly to a kind of heparin sodium except color tank.
Background technology
Heparin sodium is to use anticoagulant most, widest clinically, and the composite form with albumen occurs in vivo.This complex does not has anticoagulant active, only is separately separated out and just can show anticoagulant active.Heparin sodium is widely distributed at biosphere, is present in higher mammal, in the lung tissue of pig, cattle, sheep etc., intestinal tissue.Common heparin sodium separate mode has enzymolysis or salt solution, precipitate with ethanol, oxidation etc., due to source and the extracting mode of heparin, necessarily contains substantial amounts of nucleic acid and protein impurities, deeper color in crude product heparin.
The most domestic only heparin sodium except color technique, still lack heparin sodium except the Special Equipment of color.
Utility model content
The technical problems to be solved in the utility model is to provide a kind of convenience heparin sodium except color except color tank.
For solving above-mentioned technical problem, the technical solution of the utility model is: a kind of heparin sodium is except color tank, and its innovative point is: includes dissolving tank and the separatory tank connected up and down, has a controlled valve between described dissolving tank and separatory tank；Described dissolving tank upper end has acid-alkali accommodation hole A and feeding mouth A, there is inside it agitating device A, described agitating device includes the motor being fixed on dissolving tank upper surface, the shaft being connected on motor and the stirrer gear being positioned on shaft, and the lower end of this dissolving tank has a screen cloth；Described separatory tank upper end has an an acid-alkali accommodation hole B and feeding mouth B, has an agitating device B, described agitating device B identical with agitating device A structure inside it, and this separatory tank lateral wall has a temperature control coil pipe.
Further, described dissolving tank lower end connects some separatory tanks.
Further, described separatory tank has the observation window being vertically arranged along separatory pot sidewall.
The utility model has the advantage of:
1) this utility model one heparin sodium removes color tank, each technical process is incorporated in an equipment, it is simple to practical operation, adapts to large batch of production, it is not necessary to switched the most back and forth by solution；
2) because separatory tank needs to stand separatory, but within this time period, closing the switch valve of this separatory tank, the switch valve opening other separatory tanks just can be carried out except color operates on other separatory tanks；
3) solution after separatory needs to extract the supernatant out, and observation window is easy to observe the separatory situation of solution.
Accompanying drawing explanation
Fig. 1 is that a kind of heparin sodium of this utility model is except the schematic diagram of color tank.
Detailed description of the invention
As it is shown in figure 1, the utility model discloses a kind of heparin sodium to remove color tank, including having a controlled valve 11 between the dissolving tank 13 connected up and down and separatory tank 9, dissolving tank 13 and separatory tank 9；Dissolving tank 13 upper end has acid-alkali accommodation hole A1 and feeding mouth A3, there is inside it agitating device A, agitating device A includes the motor 2 being fixed on dissolving tank upper surface, be connected on motor shaft 4 and the stirrer gear 5 being positioned on shaft 4, the lower end of this dissolving tank 13 has a screen cloth 12；Separatory tank 9 upper end has an an acid-alkali accommodation hole B6 and feeding mouth B7, has an agitating device B, agitating device B identical with agitating device A structure inside it, and this separatory tank 9 lateral wall has a temperature control coil pipe 10；Dissolving tank 13 lower end connects some separatory tanks 9；There is on separatory tank 9 observation window being vertically arranged along separatory pot sidewall.
By heparin sodium in feeding mouth A renders to dissolving tank 13, obtain the heparin sodium aqua that concentration is 6000 ~ 8000IU/l, hydrochloric acid is rendered to heparin sodium aqua from acid-alkali accommodation hole A1, the pH of heparin sodium aqua is adjusted to 1.0 ~ 2.5；Sodium sulfite, stirring reaction 0.5h is thrown in again at feeding mouth A3；Adding mass concentration in the solution obtained is 1% kieselguhr, opens switch valve 11, and filtrate flows in separatory tank 9, and kieselguhr residue is stayed on filter screen 12；In separatory tank 9, throw in sodium hydroxide solution regulation filtrate from acid-alkali accommodation hole B6, regulate while stirring, make pH=4.0 ~ 4.5；Adding mass concentration in gained solution is 0.5 ~ 0.7%EDTA, reacts 1h；Adding 2.5% solid sodium chloride, stirring makes solid sodium chloride dissolve；Steam or hot water is passed in the temperature control coil pipe 10 of separatory tank 9 outer wall, make solution temperature keep 55 ~ 65 DEG C, add 0.8 times of ethanol, by the steam in temperature control coil pipe 10 or hot water emptying after stirring 0.5h, and again it is passed through cooling water, make gained solution temperature be cooled to 20 ~ 25 DEG C；Mixture in separatory tank 9 is staticly settled, the supernatant after precipitation be waste ethanol, lower sediment thing be the mixture containing heparin sodium, use water pump also to coordinate observation window 8, pump upper strata waste ethanol, to the dehydration of lower sediment thing, be dried to obtain heparin sodium product.
Of the present utility model ultimate principle and principal character have more than been shown and described.Skilled person will appreciate that of the industry; this utility model is not restricted to the described embodiments; described in above-described embodiment and description, principle of the present utility model is simply described; on the premise of without departing from this utility model spirit and scope; this utility model also has various changes and modifications, in the range of these changes and improvements both fall within claimed this utility model.This utility model claims scope and is defined by appending claims and equivalent thereof.
Claims (3)
1. a heparin sodium is except color tank, it is characterised in that: include dissolving tank and the separatory tank connected up and down, between described dissolving tank and separatory tank, there is a controlled valve；Described dissolving tank upper end has acid-alkali accommodation hole A and feeding mouth A, there is inside it agitating device A, described agitating device includes the motor being fixed on dissolving tank upper surface, the shaft being connected on motor and the stirrer gear being positioned on shaft, and the lower end of this dissolving tank has a screen cloth；Described separatory tank upper end has an an acid-alkali accommodation hole B and feeding mouth B, has an agitating device B, described agitating device B identical with agitating device A structure inside it, and this separatory tank lateral wall has a temperature control coil pipe.
A kind of heparin sodium the most according to claim 1 is except color tank, it is characterised in that: described dissolving tank lower end connects some separatory tanks.
A kind of heparin sodium the most according to claim 1 is except color tank, it is characterised in that: on described separatory tank, there is the observation window being vertically arranged along separatory pot sidewall.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520823872.8U CN205443145U (en) | 2015-10-23 | 2015-10-23 | Liquaemin removes look jar |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520823872.8U CN205443145U (en) | 2015-10-23 | 2015-10-23 | Liquaemin removes look jar |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205443145U true CN205443145U (en) | 2016-08-10 |
Family
ID=57179539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520823872.8U Expired - Fee Related CN205443145U (en) | 2015-10-23 | 2015-10-23 | Liquaemin removes look jar |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN205443145U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106967188A (en) * | 2017-05-31 | 2017-07-21 | 广元市海鹏生物科技有限公司 | A kind of liquaemin removes color method |
-
2015
- 2015-10-23 CN CN201520823872.8U patent/CN205443145U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106967188A (en) * | 2017-05-31 | 2017-07-21 | 广元市海鹏生物科技有限公司 | A kind of liquaemin removes color method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170807 Address after: 224200 No. two, No. 20, Port District, Dongtai coastal economic zone, Jiangsu, China Patentee after: JIANGSU WANLI BIOTECHNOLOGY CO., LTD. Address before: 226500, Rugao City, Jiangsu province Nantong City, such as Huimin Road No. 666 (casing City 801) Patentee before: NANTONG RENSHOU FOODS CO., LTD. |
|
| TR01 | Transfer of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160810 Termination date: 20171023 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |