CN205434001U - D shape intervention formula artificial heart valve - Google Patents
D shape intervention formula artificial heart valve Download PDFInfo
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- CN205434001U CN205434001U CN201620107104.7U CN201620107104U CN205434001U CN 205434001 U CN205434001 U CN 205434001U CN 201620107104 U CN201620107104 U CN 201620107104U CN 205434001 U CN205434001 U CN 205434001U
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Abstract
The utility model provides a D shape intervention formula artificial heart valve, including the support, set up in the inboard lamella leaf of support and set up the tectorial membrane on the support body wall, the support is including the sub - support of first sub - support, second and the sub - support of third that connect gradually, first sub - support be the network management, network management that the sub - support of second appeared for D for the cross section, the sub - support of third is loudspeaker and describes the network management, the biggest pipe diameter of first sub - support is the same with the pipe diameter of the sub - support of second, and the minimum pipe diameter of the sub - support of third is the same with the pipe diameter of the sub - support of second. Through the network management that appears for the cross section the support of second design for D, erect with the D shape intervention formula artificial heart valve medium counts that has now and count the cross -section and compare for the circular shape tubulose, the shape of the sub - support of second is identical with the holding space shape that the mitral primary body wall of normal position encloses to the problem of avoiding its oppression to the heart efferent tract to cause the patient other complication to appear when using has improved the success rate of operation.
Description
Technical field
This utility model relates to technical field of medical instruments, particularly to a kind of D-shaped insertion type artificial cardiac valve.
Background technology
Heart is the very important organ of human body, power is provided for blood circulation of human body, heart is divided into left and right two parts, every part comprises a ventricle and atrium, separated by interventricular septum and interatrial septum between ventricle and ventricle and between atrium and atrium, there is between room, room, tremulous pulse the valve preventing blood reflux.
Mitral position is between left atrium and left ventricle, such as same one-way cock, it is ensured that blood is flowed to left ventricle direction by left atrium and passes through certain flow.Mitral complex is one group of function and dissects baroque device, it is generally recognized that include annulus, leaflet, chordae tendineae and papillary muscles.Mitral function depends on the integrity of its physiological structure.During normal MC, two leaflets be in approximately the same plane and involutory closely, it is possible to stop the backflow of ventricular blood flow completely.Reach such effect, it is desirable to annulus of mitral valve size to fit, leaflet structural integrity, papillary muscle retracts tractive chordae tendineae play the closedown strength that the supporting role of leaflet, left ventricle muscle contraction are produced suitably, ventricular morphology and function normal.In these factors, any one occurs extremely all to cause mitral incompetence (MR).
The cause of disease most commonly valvular heart disease, women is more common.Functional mitral incompetence that papillary muscles nonfunction that other commonly encountered diseases cause because including mitral valve prolapse, Bicuspid valve degeneration, mitral annular calcification, myocardial ischemia, left ventricular enlargement cause, infective endocarditis, congenital malformation etc..Surgery prosthetic valve replacement operation wound is big, and the recovery time of patient is long, therefore to gerontal patient often because of advanced age, body constitution is weak, pathological changes is heavy or merges Other diseases and avoids performing the operation.
In recent years, along with the progress of interventional therapeutic technique, it is developed rapidly through catheter heart valves displacement or prothesis and is applied to clinic, achieving more satisfied effect.Get involved operation by Wicresoft to be implanted in the original position Bicuspid valve of heart by insertion type artificial cardiac valve, carry out related work with the natural valve of displacement or reparation infringement.Described insertion type artificial cardiac valve mainly includes support, and it is arranged at the leaflet of internal stent, operation process is without opening breast, thus wound is little, post-operative recovery is fast, its life can not be extended for those current conventional therapy means or alleviate the valvular stenosis patient of its misery, it is provided that a kind of new solution.
But owing to interventional therapeutic technique time of occurrence is shorter, during application, also face more problem.Such as some insertion type artificial cardiac valves are not enough due to support force in use, are easily broken off；Support is inadequate with the physiological structure degree of agreement of natural valve, is susceptible to perivalvular leakage；Supporting structure easily oppresses heart efferent tract；Supporting structure is long excessive, injures heart；Development point design is unreasonable, affects operation technique.For the problem existing for existing insertion type artificial cardiac valve, the method that those skilled in the art always search for solving.
Summary of the invention
The purpose of this utility model is to provide a kind of D-shaped insertion type artificial cardiac valve, the problem that there is compressing heart efferent tract during to solve the application of existing insertion type artificial cardiac valve.
For solving above-mentioned technical problem, this utility model provides a kind of D-shaped insertion type artificial cardiac valve, and described insertion type artificial cardiac valve includes: support, is arranged at the leaflet inside described support and is arranged at the overlay film on described support body wall；Wherein,
Described support includes the first submounts, the second submounts and the 3rd submounts being sequentially connected with, and described first submounts is webmaster, described second submounts be cross section be the webmaster of D-shaped, described 3rd submounts is horn-like webmaster；The maximum caliber of described first submounts is identical with the caliber of described second submounts, and the minimum pipe of described 3rd submounts is identical with the caliber of described second submounts.
Optionally, in described D-shaped insertion type artificial cardiac valve, described second submounts includes straight body wall and arc body wall, described straight body wall and described arc body wall are connected with each other and surround the webmaster that cross section is D-shaped, and the body wall of described 3rd submounts is more than the body wall angle of inclination relative to the arc body wall of described second submounts of described 3rd submounts relative to the angle of inclination of the straight body wall of described second submounts.
Optionally, in described D-shaped insertion type artificial cardiac valve, described first submounts is circular cone shape webmaster, and the body wall of the most described second submounts of body wall of described first submounts tilts 10 degree～60 degree.
Optionally, in described D-shaped insertion type artificial cardiac valve, the body wall of described first submounts or described second submounts being provided with agnail, the free end of described agnail tilts along the direction of the free end deviating from described first submounts.
Optionally, in described D-shaped insertion type artificial cardiac valve, also including the point that develops, described development point is arranged on the overlay film on described 3rd submounts and/or on described 3rd submounts.
Optionally, in described D-shaped insertion type artificial cardiac valve, the quantity of described development point is 3, wherein 2 development points are arranged on described 3rd submounts being connected with the straight body wall of described second submounts, and other 1 development point is arranged on the overlay film of described 3rd submounts being connected with the arc body wall of described second submounts.
Optionally, in described D-shaped insertion type artificial cardiac valve, the quantity of described leaflet is at least two panels.
Optionally, in described D-shaped insertion type artificial cardiac valve, described leaflet is the valve prepared of biological tissue, macromolecular material or tissue engineered heart valve.
Optionally, in described D-shaped insertion type artificial cardiac valve, described first submounts or described second submounts are provided with leaflet sewing hole, by described leaflet sewing hole, described leaflet are sutured on described support.
Optionally, in described D-shaped insertion type artificial cardiac valve, the material of described support is Nitinol, and the material of described overlay film is PET, one or more in e-PTFE, pericardium material.
At D-shaped insertion type artificial cardiac valve provided by the utility model, described D-shaped insertion type artificial cardiac valve includes support, is arranged at the leaflet inside support and is arranged at the overlay film on support body wall, support includes the first submounts, the second submounts and the 3rd submounts being sequentially connected with, first submounts is webmaster, second submounts be cross section be the webmaster of D-shaped, the 3rd submounts is horn-like webmaster；The maximum caliber of the first submounts and the caliber of the second submounts are identical, and the minimum pipe of the 3rd submounts is identical with the caliber of the second submounts.By the second submounts being designed as the webmaster that cross section is D-shaped, being designed as cross section with existing D-shaped insertion type artificial cardiac valve medium-height trestle is compared with circular tubulose, the shape of described second submounts matches with the accommodation space shape that mitral primary body wall surrounds in situ, thus avoid it that compressing of heart efferent tract causes patient other the problem of complication occur in use, improve the success rate of operation.
Accompanying drawing explanation
Fig. 1 is the structural representation of the original position PM that D-shaped insertion type artificial cardiac valve is implanted to heart in this utility model one embodiment；
Fig. 2 is the front view of the support of D-shaped insertion type artificial cardiac valve in this utility model one embodiment；
Fig. 3 is the front view in this utility model one embodiment after the support overlay film of D-shaped insertion type artificial cardiac valve；
Fig. 3 a is the top view after the inside of the support of Fig. 3 is sewed with leaflet.
In figure: support 1；Leaflet 2；Overlay film 3；First submounts 10；Second submounts 11；Leaflet sewing hole 110；Straight body wall 111；Arc body wall 112；3rd submounts 12；Agnail 4；Conveying connection member 5；Development point 6.
Detailed description of the invention
Below in conjunction with the drawings and specific embodiments, the D-shaped insertion type artificial cardiac valve that the utility model proposes is described in further detail.According to following explanation and claims, advantage of the present utility model and feature will be apparent from.It should be noted that, accompanying drawing all uses the form simplified very much and all uses non-ratio accurately, only in order to purpose convenient, aid illustration this utility model embodiment lucidly.
Before illustrating this utility model, cardinal principle and the thought of this utility model is first described at this.The problem that there is compressing heart efferent tract for existing existing insertion type artificial cardiac valve when applying, inventor of the present utility model finds through long-term experimental verification, the reason causing above-mentioned phenomenon is, owing to the supporting structure of existing insertion type artificial cardiac valve is tubulose, owing to the cross sectional shape in the space of accommodating insertion type artificial cardiac valve is not circular, but D-shaped, therefore after inserting at the insertion type artificial cardiac valve that support is tubulose in the original position Bicuspid valve of heart, the sidewall that accommodation space is straight can be caused compressing, the efferent tract causing heart becomes narrow.Discovery based on this problem, it is proposed that the technical solution of the utility model, the technical solution of the utility model is mainly carried out from the shape design of support.
Fig. 1 is the structural representation that D-shaped insertion type artificial cardiac valve of the present utility model is implanted to the original position PM of heart.Fig. 2 is the front view of the support of this utility model D-shaped insertion type artificial cardiac valve.Fig. 3 is the front view in this utility model one embodiment after the support overlay film of D-shaped insertion type artificial cardiac valve.Fig. 3 a is the top view after the inside of the support of Fig. 3 is sewed with leaflet.As shown in Fig. 2, Fig. 3-Fig. 3 a, D-shaped insertion type artificial cardiac valve of the present utility model includes: support 1, is arranged at the leaflet 2 inside described support 1 and is arranged at the overlay film 3 on described support 1 body wall；Wherein, described support 1 includes the first submounts the 10, second submounts 11 and the 3rd submounts 12 being sequentially connected with, and described first submounts 10 is webmaster, and described second submounts 11 is the webmaster of D-shaped for cross section, and described 3rd submounts 12 is in horn-like webmaster；The maximum caliber of described first submounts 10 is identical with the caliber of described second submounts 11, and the minimum pipe of described 3rd submounts 12 is identical with the caliber of described second submounts 11.
Refer to Fig. 3, described second submounts includes straight body wall 111 and arc body wall 112, described straight body wall 111 and described arc body wall 112 are connected with each other and surround the webmaster that cross section is D-shaped, so that the structure and morphology of the D-shaped insertion type artificial cardiac valve of preparation meets the cross sectional shape in the space of accommodating D-shaped insertion type artificial cardiac valve, it is to avoid cause the compressing to heart efferent tract owing to supporting structure is unreasonable；Wherein, the body wall of described 3rd submounts is more than the body wall angle of inclination relative to the arc body wall 112 of described second submounts of described 3rd submounts relative to the angle of inclination of the straight body wall 111 of described second submounts, comply with the topographic profile of primary structure further, it is to avoid the damage that heart tissue is caused by the 3rd submounts structure.During actual application, after D-shaped insertion type artificial cardiac valve is inserted in the original position Bicuspid valve of heart, the straight body wall of the second submounts is near heart efferent tract side.
Further, it is circular cone shape webmaster by described first submounts here, thus reduces the length of whole support, it is to avoid after implanting heart, the long injury to heartsurroundings of support.
Refer to Fig. 2, described first submounts the 10, second submounts 11 and the 3rd submounts 12 three are coaxial, and the difference of three is that shape is different.Actual when preparing support, it is to use same original webmaster, it is divided into three sections to carry out moulding technology original webmaster, when preparing the second submounts 11, by this section of original webmaster plasticity be cross section be the webmaster of D type, the first submounts 10 is the edge radial contraction along original webmaster of the one end by original webmaster, presents the shape as being numbered 10 parts in Fig. 2, the angle, θ that the body wall of the most described second submounts 11 of body wall of the first submounts 10 described here tilts is 10 degree～60 degree, preferably 30 degree.
Refer to Fig. 2 and Fig. 3, the body wall of described first submounts 10 or described second submounts 11 is provided with agnail 4, the free end of described agnail 4 tilts along the direction of the free end deviating from described first submounts 10, angle between the body wall of agnail 4 and the first submounts 10 or described second submounts 11 is 10 degree～80 degree, preferred 60 degree.A length of 3mm～10mm of described agnail.During application, agnail 4 thrusts the tissue of valve periphery, plays the effect of location D-shaped insertion type artificial cardiac valve.Here, the quantity of agnail 4 is multiple, and multiple described agnails 4 are evenly distributed on the first submounts 10 or periphery of the second submounts 11.
Concrete, D-shaped insertion type artificial cardiac valve in the present embodiment can radially stretch, when installing conveying D-shaped insertion type artificial cardiac valve, for the ease of fitting tightly with destination organization, to form sufficient channel of blood flow, the structure that the structure of above-mentioned second submounts and described 3rd submounts matches is designed as the physiological structure with natural valve and matches (especially matching with the native physiological structure of mitral surrounding tissue) by this utility model, thus make it have certain self-locating function, it is easy to be quickly and accurately positioned release, and release after-poppet fits tightly channel of blood flow, it is not susceptible to displacement, simultaneously this structure coordinate with surrounding tissue be easy to overlay film formed plugging structure, be conducive to avoiding perivalvular leakage.
nullDuring actual application，D-shaped insertion type artificial cardiac valve is to be placed in implantation within a patient in conveyer device，When arriving target location，Release D-shaped insertion type artificial cardiac valve，Now the support of D-shaped insertion type artificial cardiac valve can be strutted rapidly by compressive state，Understand as shown in Figure 1，After the release of D-shaped insertion type artificial cardiac valve, the first submounts is positioned at ventricle，3rd submounts is positioned in atrium，Described 3rd submounts is as the blood inlet of blood，First submounts is as the blood outlet of blood，Caliber due to the 3rd submounts is more than the caliber of described second submounts，When because of diastole, the 3rd submounts can be played barrier effect and prevent the centripetal indoor landing of D-shaped insertion type artificial cardiac valve by natural plate ring tissue，And when the heart contracts，Owing to the effect of agnail can stop again D-shaped insertion type artificial cardiac valve to move to atrium，Therefore based on supporting structure of the present utility model，It is shifted under washing away in blood stream pressure after can more efficiently preventing from the release of D-shaped insertion type artificial cardiac valve，Extend the service life after the release of D-shaped insertion type artificial cardiac valve，Reduce its injury to surrounding tissue.
As shown in Figure 3 a, would know that distributing position and the shape thereof of leaflet 2, in the present embodiment, the quantity of described leaflet 2 is at least two panels, and described leaflet is the valve prepared of biological tissue's (such as Cor Sus domestica bag, bovine pericardium, Cor Sus domestica lobe, Cor Bovis seu Bubali lobe etc.), macromolecular material or tissue engineered heart valve.Wherein, described leaflet includes rectangular portion and the curved portions being connected with described rectangular portion, uses the leaflet of this shape to be easy to coordinate stitching, and the hemodynamic effect of gained valve is good.Wherein, as in figure 2 it is shown, in order to leaflet be arranged in described support, this utility model is provided with leaflet sewing hole 110 on described first submounts or described second submounts, described leaflet is sutured on described support by described leaflet sewing hole 110.
Further, refer to Fig. 2 and Fig. 3, be combined with conveyer device in delivery phase for the ease of D-shaped insertion type artificial cardiac valve, the free end at described first submounts is provided with conveying connection member 5, and the quantity of described conveying connection member 5 is at least 2.
Refer to Fig. 2 and Fig. 3 a, in order to meet location and the position of observation D-shaped insertion type artificial cardiac valve, development point 6 it is provided with on overlay film on described 3rd submounts and/or on described 3rd submounts, the quantity of described development point 6 is 3, wherein 2 development points are arranged on described 3rd submounts being connected with the straight body wall of described second submounts, other 1 development point is arranged on the overlay film of described 3rd submounts being connected with the arc body wall of described second submounts, 3 development points constitute a plane, arrive when D-shaped insertion type artificial cardiac valve inserts heart when target location, two the development points being arranged on described 3rd submounts that straight body wall connects are on same straight line, observation is shown as same point.Concrete, if development point 6 is arranged on the 3rd submounts, the outer wall on the most described 3rd submounts needs be provided with development hole, described development hole is filled with developing media；If development point 6 is arranged in overlay film, then the covering material of position development point 6 being set at needs adds developing media.Above-mentioned developing media is one or more in platinumiridio (Pt/Ir), platinum (Pt), tantalum metal (Ta).
It is also preferred that the left the material of described support is Nitinol, the material of described overlay film is PET, one or more in e-PTFE, pericardium material.
Preferably, the mesh shape of the cylindric webmaster of described second submounts is designed as rhombus, to improve D-shaped insertion type artificial cardiac valve in use support force, it is to avoid the problem occurring causing the fracture of support due to support force deficiency.
To sum up, in D-shaped insertion type artificial cardiac valve provided by the utility model, described D-shaped insertion type artificial cardiac valve includes support, is arranged at the leaflet inside support and is arranged at the overlay film on support body wall, support includes the first submounts, the second submounts and the 3rd submounts being sequentially connected with, first submounts is webmaster, second submounts be cross section be the webmaster of D-shaped, the 3rd submounts is horn-like webmaster；The maximum caliber of the first submounts and the caliber of the second submounts are identical, and the minimum pipe of the 3rd submounts is identical with the caliber of the second submounts.By the second submounts being designed as the webmaster that cross section is D-shaped, being designed as cross section with existing D-shaped insertion type artificial cardiac valve medium-height trestle is compared with circular tubulose, the accommodation space shape that the shape of described second submounts surrounds with in situ mitral primary body wall matches, thus avoids it that compressing of heart efferent tract causes patient other the problem of complication occur in use；On the other hand, in this utility model, the first submounts is designed as circular cone shape webmaster, shortens support overall length, it is to avoid thrust the injury that heart is caused by surrounding heart tissue owing to support is long, improves the success rate of operation；On the other hand, owing to being provided with agnail on the body wall of described first submounts or described second submounts, agnail can thrust the tissue of valve periphery after cardiac valve is implanted to ad-hoc location, play positioning action so that after the release of D-shaped insertion type artificial cardiac valve, be not susceptible to displacement and perivalvular leakage；On the other hand, the position arranged based on this utility model development point is relatively reasonable, meets the demand of operation.
Foregoing description is only the description to this utility model preferred embodiment; the not any restriction to this utility model scope; any change that the those of ordinary skill in this utility model field does according to the disclosure above content, modification, belong to the protection domain of claims.
Claims (10)
1. a D-shaped insertion type artificial cardiac valve, it is characterised in that including: support, be arranged at the leaflet inside described support and be arranged at the overlay film on described support body wall；Wherein,
Described support includes the first submounts, the second submounts and the 3rd submounts being sequentially connected with, and described first submounts is webmaster, described second submounts be cross section be the webmaster of D-shaped, described 3rd submounts is horn-like webmaster；The maximum caliber of described first submounts is identical with the caliber of described second submounts, and the minimum pipe of described 3rd submounts is identical with the caliber of described second submounts.
2. D-shaped insertion type artificial cardiac valve as claimed in claim 1, it is characterized in that, described second submounts includes straight body wall and arc body wall, described straight body wall and described arc body wall are connected with each other and surround the webmaster that cross section is D-shaped, and the body wall of described 3rd submounts is more than the body wall angle of inclination relative to the arc body wall of described second submounts of described 3rd submounts relative to the angle of inclination of the straight body wall of described second submounts.
3. D-shaped insertion type artificial cardiac valve as claimed in claim 1, it is characterised in that described first submounts is circular cone shape webmaster, and the body wall of the most described second submounts of body wall of described first submounts tilts 10 degree～60 degree.
4. D-shaped insertion type artificial cardiac valve as claimed in claim 1, it is characterised in that be provided with agnail on the body wall of described first submounts or described second submounts, the free end of described agnail tilts along the direction of the free end deviating from described first submounts.
5. D-shaped insertion type artificial cardiac valve as claimed in claim 2, it is characterised in that also including the point that develops, described development point is arranged on the overlay film on described 3rd submounts and/or on described 3rd submounts.
6. D-shaped insertion type artificial cardiac valve as claimed in claim 5, it is characterized in that, the quantity of described development point is 3, wherein 2 development points are arranged on described 3rd submounts being connected with the straight body wall of described second submounts, and other 1 development point is arranged on the overlay film of described 3rd submounts being connected with the arc body wall of described second submounts.
7. D-shaped insertion type artificial cardiac valve as claimed in claim 1, it is characterised in that the quantity of described leaflet is at least two panels.
8. D-shaped insertion type artificial cardiac valve as claimed in claim 7, it is characterised in that described leaflet is the valve prepared of biological tissue, macromolecular material or tissue engineered heart valve.
9. the D-shaped insertion type artificial cardiac valve as according to any one of claim 1-8, it is characterised in that be provided with leaflet sewing hole on described first submounts or described second submounts, by described leaflet sewing hole, described leaflet be sutured on described support.
10. the D-shaped insertion type artificial cardiac valve as according to any one of claim 1-8, it is characterised in that the material of described support is Nitinol, the material of described overlay film is PET, one in e-PTFE, pericardium material.
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| CN201620107104.7U CN205434001U (en) | 2016-02-02 | 2016-02-02 | D shape intervention formula artificial heart valve |
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| CN201620107104.7U CN205434001U (en) | 2016-02-02 | 2016-02-02 | D shape intervention formula artificial heart valve |
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Cited By (7)
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| CN105520792A (en) * | 2016-02-02 | 2016-04-27 | 上海纽脉医疗科技有限公司 | D-shaped invasive prosthetic heart valve |
| CN106175987A (en) * | 2016-08-31 | 2016-12-07 | 上海纽脉医疗科技有限公司 | Cardiac valve prosthesis |
| CN107890382A (en) * | 2017-12-20 | 2018-04-10 | 乐普（北京）医疗器械股份有限公司 | It can position recyclable through conduit implanted aorta petal film device |
| WO2019062366A1 (en) * | 2017-09-29 | 2019-04-04 | 上海微创心通医疗科技有限公司 | Heart valve prosthesis |
| CN110621260A (en) * | 2017-01-23 | 2019-12-27 | 科菲瓣膜技术有限公司 | Replacement mitral valve |
| US11058535B2 (en) | 2017-01-23 | 2021-07-13 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| US11617646B2 (en) | 2015-05-14 | 2023-04-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
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| US11617646B2 (en) | 2015-05-14 | 2023-04-04 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| CN105520792A (en) * | 2016-02-02 | 2016-04-27 | 上海纽脉医疗科技有限公司 | D-shaped invasive prosthetic heart valve |
| US10842621B2 (en) | 2016-08-31 | 2020-11-24 | Shanghai Newmed Medical Co., Ltd. | Artificial cardiac valve |
| CN106175987A (en) * | 2016-08-31 | 2016-12-07 | 上海纽脉医疗科技有限公司 | Cardiac valve prosthesis |
| WO2018040244A1 (en) * | 2016-08-31 | 2018-03-08 | 上海纽脉医疗科技有限公司 | Artificial cardiac valve |
| CN112566590A (en) * | 2017-01-23 | 2021-03-26 | 科菲瓣膜技术有限公司 | Replacement mitral valve |
| CN110621260A (en) * | 2017-01-23 | 2019-12-27 | 科菲瓣膜技术有限公司 | Replacement mitral valve |
| JP2020505980A (en) * | 2017-01-23 | 2020-02-27 | セフィア・バルブ・テクノロジーズ, インコーポレイテッドCephea Valve Technologies, Inc. | Replacement mitral valve |
| US11058535B2 (en) | 2017-01-23 | 2021-07-13 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| US11090158B2 (en) | 2017-01-23 | 2021-08-17 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| JP7046078B2 (en) | 2017-01-23 | 2022-04-01 | セフィア・バルブ・テクノロジーズ，インコーポレイテッド | Replacement mitral valve |
| US11633278B2 (en) | 2017-01-23 | 2023-04-25 | Cephea Valve Technologies, Inc. | Replacement mitral valves |
| WO2019062366A1 (en) * | 2017-09-29 | 2019-04-04 | 上海微创心通医疗科技有限公司 | Heart valve prosthesis |
| WO2019119674A1 (en) * | 2017-12-20 | 2019-06-27 | 乐普（北京）医疗器械股份有限公司 | Aortic valve device and delivery device |
| CN107890382A (en) * | 2017-12-20 | 2018-04-10 | 乐普（北京）医疗器械股份有限公司 | It can position recyclable through conduit implanted aorta petal film device |
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