CN205234457U - Draw device of matrix blood vessel component among follow autologous adipose tissue - Google Patents

Draw device of matrix blood vessel component among follow autologous adipose tissue Download PDF

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Publication number
CN205234457U
CN205234457U CN201520891901.4U CN201520891901U CN205234457U CN 205234457 U CN205234457 U CN 205234457U CN 201520891901 U CN201520891901 U CN 201520891901U CN 205234457 U CN205234457 U CN 205234457U
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China
Prior art keywords
fatty
blood vessel
filter holder
container tube
vessel component
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Expired - Fee Related
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CN201520891901.4U
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Chinese (zh)
Inventor
李宏
王钰安
李博文
王福来
杨琳
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Hangzhou Dianzi University
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Hangzhou Dianzi University
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Priority to CN201520891901.4U priority Critical patent/CN205234457U/en
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Publication of CN205234457U publication Critical patent/CN205234457U/en
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Abstract

The utility model discloses a draw device of matrix blood vessel component among follow autologous adipose tissue for draw with purification matrix blood vessel component, the device is including fatty container pipe, fat container pipe upper end is the opening, the fatty delivery outlet of lower extreme for narrowing, the device includes still that the closing cap filters the support on the opening part of fatty container pipe upper end to and be located the lower filtration support of fatty container socle portion, on filter and be provided with fatty filling opening and washing liquid filling opening on the support, be provided with filtration membrane between fat filling opening and the last filtration support bottom surface, under filter and be provided with down filtration membrane between support and the fatty delivery outlet. This device structure is exquisite, easy operation, and the suitability is good, and safe and reliable provides a new device for biomedical engineering field autologous adipose tissue draws with purification matrix blood vessel component.

Description

A kind of device that extracts matrix blood vessel component from autologous fat tissue
Technical field
The utility model patent belongs to biomedical engineering field, relates to a kind of from autologous fat tissueExtract the device of matrix blood vessel component.
Background technology
Individualized treatment is the significant progress of modern medicine, the cell therapy body including stem cellShow the core that transforms medical science and individualized treatment, matrix blood vessel component (StromalVascularFraction, SVF) refer to that adipose tissue removes after mature fat cell, what obtain has a stem cell spyThe stroma cell of property is one group of mixed cell population. Matrix blood vessel component comprises: fatty prerequisite cell,Mescenchymal stem cell, Hematopoietic Stem (ancestral) cell, endothelial progenitor cells, lymphocyte (comprise modulabilityT cell) and macrophage etc. Clinically to diabetes, systemic loupus erythematosus, systemic lupus erythematosus kidneyInflammation has obvious curative effects. In beauty industry, matrix blood vessel component is fed back in patient body and goes to wrinkle, enlarge the bosomDeng beauty treatment, there is the advantages such as immunological rejection is little, the retention time is of a specified duration, cosmetic result is good.
But, from adipose tissue, obtain at present matrix blood vessel component and lack simple effective method.
Summary of the invention
The purpose of this utility model is to provide a kind of matrix blood vessel component of extracting from autologous fat tissueDevice, adopt the mode that hand hoodle clashes into obtain matrix blood vessel component, for clinical treatment providesA set of simple device.
To achieve these goals, the technical solution of the utility model is as follows:
From autologous fat tissue, extract a device for matrix blood vessel component, obtain matrix blood vessel groupPoint, described device comprises fatty container tube, and described fatty container tube upper end is opening, and lower end is for narrowingFatty delivery outlet, described device also comprises that the upper filtration that is sealed on fatty container tube upper end open place props upFrame, and be positioned at the lower filter holder bottom fatty container tube, on described upper filter holder, be provided with fatFat inlet and cleaning fluid inlet, be provided with between described fatty inlet and upper filter holder bottom surfaceUpper filter membrane, is provided with lower filter membrane between described lower filter holder and fatty delivery outlet.
Further, between described upper filter membrane and fatty inlet, be provided with waste storage chamber, forThe impurity of stored filter.
Further, described fatty container tube inside is placed with steel ball, described upper filter holder bottom surface pairThe position of the upper filter membrane of Ying Yu is set to netted upper looping pit, and described lower filter holder is corresponding to lower filtrationThe position of film is set to netted lower looping pit. Stainless at 3-7 in the inner quantity of placing of fatty container tubeSteel bomb pearl, object is in shake process, to play mutual shock, smashes lipochondrion and discharges component cellsEffect, be more conducive to fatty homogeneous processing.
Further, between described upper filter holder and fatty container tube inwall, be provided with sealing ring,Between described lower filter holder and fatty container tube inwall, be provided with lower seal.
The edge of fatty container tube upper end open described in the utility model stretches out, upper filter holderTop stretches out and the peripheral adjustment of fatty container tube upper end open accordingly, under upper filter holderThe caliber of portion and fatty container tube adapts to, and when mounted, the bottom of upper filter holder extend into fat and holdsThe inside of organ pipe, the top of upper filter holder is sealed on the edge of fatty container tube.
Further, on described upper filter holder, be also provided with gas outlet, make device inside and outsideCarry out free air exchange, keep fat in normal acid-base value environment, simultaneously to extract waste liquidWith matrix blood vessel component.
Further, described fatty inlet, cleaning fluid inlet and gas outlet are also provided with check valveDoor. Prevent the reverse outflow of liquid and air.
A kind of device that extracts matrix blood vessel component from autologous fat tissue the utility model proposes,Injection by cleaning fluid and discharge complete cleans purifying to the autologous fat in fatty container tube,And with manual mode, up and down reciprocatingly shake rapidly fatty container tube and filter out knot useless and form groupKnit, put into some steel balls in fatty container tube, reach fat in container tube is carried out with the collision of steel ballThe effect of broken homogeneous processing. Device of the present utility model, has facilitated biomedical engineering field people fatFat is organized extraction, the purifying of each component cells, the operation of homogeneous, for obtain purification degrees high, be rich in eachThe matrix blood vessel component cells of planting growth factor provides a kind of new means. Can obtain high-quality autologousFeed back matrix blood vessel component, improve the time of result for the treatment of, shortening beauty treatment, improve beauty treatmentQuality, the postoperative effect having reached is significant.
Brief description of the drawings
Fig. 1 is the device outline drawing that the utility model extracts matrix blood vessel component;
Fig. 2 is the device sectional view that the utility model extracts matrix blood vessel component.
In figure, description of reference numerals is as follows:
1, fatty container tube; 2, upper filter holder; 3, fatty inlet; 4, cleaning fluid inlet;5, gas outlet; 6, fatty delivery outlet; 7, lower seal; 8, lower filter holder; 9, upper annularHole; 10, waste storage chamber; 12, upper sealing ring; 13, upper filter membrane; 14, lower looping pit; 15,Lower filter membrane.
Detailed description of the invention
Below in conjunction with drawings and Examples, technical solutions of the utility model are described in further details, withLower embodiment does not form restriction of the present utility model.
As depicted in figs. 1 and 2, the present embodiment one is extracted matrix blood vessel group from autologous fat tissueThe device dividing, this device comprises fatty container tube 1, upper filter holder 2 and lower filter holder 8, fatFat container tube 1 upper end is opening, and lower end is the fatty delivery outlet 6 narrowing, upper filter holder 2 cappingsAt fatty container tube 1 upper end open place, lower filter holder 8 is positioned at the bottom of fatty container tube 1.
On upper filter holder 2, be provided with fatty inlet 3 and cleaning fluid inlet 4, fatty inlet3 and upper filter holder 2 bottom surfaces between be provided with filter membrane 13, upper filter membrane 13 injects with fatBetween mouth 3, be provided with waste storage chamber 10; Between lower filter holder 8 and fatty delivery outlet 6, be provided withLower filter membrane 15.
The autologous fat taking out in human body is injected into fat by fatty inlet 3 through upper filter membrane 13In fat container tube 1, process, the impurity in fat can and be stayed upper mistake by upper filter membrane 13 eliminationsIn the waste storage chamber 10 on filter membrane 13 tops. Then, the cleaning fluid that reaches GMP standard is passed throughCleaning fluid inlet 4 is injected in fatty container tube 1 fat is cleaned to purifying. Fat is processedFirst waste liquid is extracted out from fatty delivery outlet 6 afterwards, the top of fatty delivery outlet 6 is placed with lower filter membrane 15,Prevent the fat loss of purifying. Finally, adopt syringe to connect lower filter membrane 15 by the base extractingMatter blood vessel component is extracted out from fatty delivery outlet 6.
The present embodiment fat container tube 1 inside is placed with steel ball, and upper filter holder 2 bottom surfaces are corresponding to upperThe position of filter membrane 13 is set to netted upper looping pit 9, and lower filter holder 8 is corresponding to lower filter membrane15 position is set to netted lower looping pit 14.
In fatty container tube 1, put into some steel balls in advance, injecting fat and cleaning fluid to fatAfter container tube 1, manually up and down reciprocatingly shake fast fatty 1 a period of time of container tube, fatty container tubeSteel ball in 1 also can be together with the together concussion motion up and down of fatty cleaning liquid mixture, with the collision of steel ballReach the effect that the interior fat of fatty container tube 1 is carried out to broken homogeneous processing. Looping pit 9 Hes are setLower looping pit 14 not only prevents that steel ball from going out fatty container tube 1, can also be sharp by clashing into looping pitThereby in homogenizing of fat, fat is cleaned to purifying and broken homogeneous processing. If be not set toNetted looping pit, steel ball easily damages upper and lower filter membrane, and can not effectively break fatBroken homogeneous processing.
On the present embodiment, between filter holder 2 and fatty container tube 1 inwall, be provided with sealing ring 12,Between lower filter holder 8 and fatty container tube 1 inwall, be provided with lower seal 7, increase seal,Prevent the overflowing of liquid in the process of shake.
The edge of the present embodiment fat container tube 1 upper end open stretches out, upper filter holder 2 upperPortion stretches out and the peripheral adjustment of fatty container tube 1 upper end open accordingly, upper filter holder 2The caliber of bottom and fatty container tube 1 adapts to, and when mounted, the bottom of upper filter holder 2 extend intoThe inside of fat container tube 1, the top of upper filter holder 2 is sealed on the edge of fatty container tube 1.
On the present embodiment, on filter holder 2, be also provided with gas outlet 5, gas outlet 5 makes device insideCarry out free air exchange with outside, keep fat in normal acid-base value environment, simultaneously to take outGet waste liquid and fat. Also can not set out gas port 5, directly be given vent to anger by 4 conducts of cleaning fluid inletMouthful.
It should be noted that, fatty inlet 3, cleaning fluid inlet 4 and gas outlet 5 are also provided withOne-way cock, can only inject and can not flow out, and prevents in the time of shake the outflow of liquid.
Fatty container tube 1 of the present utility model, upper filter holder 2, lower filter holder 8 adopt high scoreSub-material, is convenient to disposablely use and recycle, economic environmental protection.
The present embodiment extracts the operating procedure tool of the device of matrix blood vessel component from autologous fat tissueBody is as follows:
1, upper filter holder 2 entirety of fatty container tube 1 upper end are back-outed, and to fatty container tube 1Inside put into some steel balls, then upper filter holder 2 entirety are screwed into fatty container tube 1 upper end;
2, adopt syringe that human fatty tissue is injected by fatty inlet 3, and then from clearlyWashing lotion inlet 4 injects appropriate cleaning fluid;
3, manually up and down reciprocatingly rock fast fatty 1 a period of time of container tube, waste liquid is defeated from fatOutlet 6 is extracted out, manually rocks for the second time behaviour after refilling the cleaning fluid of appropriate cleaning sterileDo.
4, repeating step 3, completes after fat-extraction and purifying matrix blood vessel component, adopts syringe to connectConnect fatty delivery outlet 6, matrix blood vessel component after treatment is extracted out and carried out clinical practice.
Device of the present utility model has completed manual extraction and purifying matrix blood from autologous fat tissuePipe component, can obtain purer matrix blood vessel component, can the each component in adipose tissue is evenly mixedClose, its advantage is delicate structure, simple to operate, and applicability is good, safe and reliable, is biomedicineEngineering field autologous fat tissue extraction and purifying matrix blood vessel component provide a kind of new device.
Above embodiment is only in order to the technical solution of the utility model to be described but not be limited,Do not deviate from the situation of the utility model spirit and essence thereof, those of ordinary skill in the art work as can rootMake various corresponding changes and distortion according to the utility model, but these corresponding changes and distortion are all answeredBelong to the protection domain of the appended claim of the utility model.

Claims (8)

1. a device that extracts matrix blood vessel component from autologous fat tissue, is characterized in that,Described device comprises fatty container tube (1), and described fatty container tube (1) upper end is opening, lower endFor the fatty delivery outlet (6) narrowing, described device also comprises and is sealed on fatty container tube (1) upper endThe upper filter holder (2) of opening part, and be positioned at the lower filter holder bottom fatty container tube (1)(8), on described upper filter holder (2), be provided with fatty inlet (3) and cleaning fluid inlet (4),Between described fatty inlet (3) and upper filter holder (2) bottom surface, be provided with filter membrane (13),Between described lower filter holder (8) and fatty delivery outlet (6), be provided with lower filter membrane (15).
2. the device of extraction matrix blood vessel component according to claim 1, is characterized in that,Between described upper filter membrane (13) and fatty inlet (3), be provided with waste storage chamber (10).
3. the device of extraction matrix blood vessel component according to claim 1, is characterized in that,Described fatty container tube (1) inside is placed with steel ball.
4. the device of extraction matrix blood vessel component according to claim 3, is characterized in that,Described upper filter holder (2) bottom surface is set to netted pressed on ring corresponding to the position of upper filter membrane (13)Shape hole (9), described lower filter holder (8) is set to net corresponding to the position of lower filter membrane (15)Looping pit under shape (14).
5. the device of extraction matrix blood vessel component according to claim 1, is characterized in that,Between described upper filter holder (2) and fatty container tube (1) inwall, be provided with sealing ring (12),Between described lower filter holder (8) and fatty container tube (1) inwall, be provided with lower seal (7).
6. the device of extraction matrix blood vessel component according to claim 1, is characterized in that,The edge of the fatty container tube of telling (1) upper end open stretch out, the top of upper filter holder (2)Stretch out accordingly and the peripheral adjustment of fatty container tube (1) upper end open, upper filter holder (2)Bottom and the caliber of fatty container tube (1) adapt to, when mounted, under upper filter holder (2)Portion extend into the inside of fatty container tube (1), and the top of upper filter holder (2) is sealed on fat and holdsOn the edge of organ pipe (1).
7. the device of extraction matrix blood vessel component according to claim 1, is characterized in that,On described upper filter holder (2), be also provided with gas outlet (5).
8. the device of extraction matrix blood vessel component according to claim 7, is characterized in that,Described fatty inlet (3), cleaning fluid inlet (4) and gas outlet (5) are also provided with check valveDoor.
CN201520891901.4U 2015-11-10 2015-11-10 Draw device of matrix blood vessel component among follow autologous adipose tissue Expired - Fee Related CN205234457U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201520891901.4U CN205234457U (en) 2015-11-10 2015-11-10 Draw device of matrix blood vessel component among follow autologous adipose tissue

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Application Number Priority Date Filing Date Title
CN201520891901.4U CN205234457U (en) 2015-11-10 2015-11-10 Draw device of matrix blood vessel component among follow autologous adipose tissue

Publications (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105380601A (en) * 2015-11-10 2016-03-09 杭州电子科技大学 Device for extracting stromal vascular fractions from autologous fat tissue
CN116478799A (en) * 2023-05-15 2023-07-25 上海威高医疗技术发展有限公司 Adipose tissue purifying device and purifying method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105380601A (en) * 2015-11-10 2016-03-09 杭州电子科技大学 Device for extracting stromal vascular fractions from autologous fat tissue
CN116478799A (en) * 2023-05-15 2023-07-25 上海威高医疗技术发展有限公司 Adipose tissue purifying device and purifying method
CN116478799B (en) * 2023-05-15 2024-05-24 上海威高医疗技术发展有限公司 Adipose tissue purifying device and purifying method

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20160518

Termination date: 20181110

CF01 Termination of patent right due to non-payment of annual fee