CN204207717U - Endoscope's illumination spectra selecting arrangement and ultraphotic spectrum endoscopic imaging system - Google Patents
Endoscope's illumination spectra selecting arrangement and ultraphotic spectrum endoscopic imaging system Download PDFInfo
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- CN204207717U CN204207717U CN201420591311.5U CN201420591311U CN204207717U CN 204207717 U CN204207717 U CN 204207717U CN 201420591311 U CN201420591311 U CN 201420591311U CN 204207717 U CN204207717 U CN 204207717U
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- light
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Abstract
The utility model discloses a kind of ultraphotic spectrum endoscopic imaging system, comprise light source, the selecting arrangement of illumination spectra, endoscope, graphics processing unit, display unit, the selecting arrangement of described illumination spectra comprises dispersion element, collecting lens, movable reflecting mirror, each different wavelengths of light of dispersion element outgoing projects movable reflecting mirror after collecting lens, by the movement of movable reflecting mirror, each wavelength light is coupled to respectively the plane of incidence of the light guide therefor of fujinon electronic video endoscope.This utility model utilizes the chromatic dispersion principle of light, uses wavelength selection system simply, conveniently to select the wavelength irradiating light, obtains the illumination spectra of any spectral coverage in tested tissue near-infrared to visible spectrum in real time; Doctor according to the optical characteristics of the state of an illness of patient and pathological tissues, can select the spectrum picture needing shooting, realizes collection of illustrative plates unification, real time spectrum imaging to biological tissue in body.
Description
Technical field
This utility model relates to a kind of light spectrum image-forming armarium based on endoscope, is specifically related to the selecting arrangement of a kind of endoscope multispectral section of illumination spectra, and in addition, this utility model also relates to the ultraphotic spectrum endoscopic imaging system using above-mentioned selecting arrangement.
Background technology
Spectral imaging technology is the combination of spectrum analysis and optical image technology, can obtain shape information and the biological tissue complete spectrum data in a certain wave-length coverage of biological tissue simultaneously.Due to biological tissue, there is under different pathological states unique reflectance spectrum, autofluorescence spectrum and bring out fluorescence spectrum, so carry out light spectrum image-forming to biological tissue and carry out certain quantitative analysis, the early diagnosis of some pathological change can be realized.Particularly the pathogeny of tumor and other diseases, clinical diagnosis, the state of an illness are detected and the research of curative effect evaluation significant.
At present in the medical field to organizing collection and the preparation carrying out light spectrum image-forming and substantially all need first to carry out sample, then use imaging spectral devices collect data.The light spectrum image-forming that this mode can not be carried out at body to biological tissue, significantly limit the application of spectral imaging technology in the field such as early diagnosis, treatment effectiveness evaluation of disease.
The equipment having pertinent literature and patent to propose multi-optical spectrum imaging technology in recent years to combine with endoscope, achieve to a certain extent to biological tissue at body light spectrum image-forming.Such as, Olympus proposes a kind of narrow-band spectrum imaging (Narrow Band Imaging) endoscope.This endoscope utilizes easily is irradiated by the light of two kinds of wavelength of hemoglobin absorption (blue light: 405nm ~ 425nm/ green light: 540 ~ 560nm) and carries out imaging, makes the blood capillary of mucosal surface and the fine structure of mucosa be emphasized to represent.Owing to can cause lesion increased vascularization when tissue produces canceration, the structure that blood capillary is formed at mucomembranous surface will change, and utilizes this point, and narrow-band spectrum imaging endoscope can provide strong help for the early discovery of cancer.
Again such as, Olympus proposes a kind of autofluorescence imaging (Auto Fluorescence Imaging) endoscope, what the utilization of this endoscope was organized brings out fluorescent characteristic, use blue light (390nm ~ 470nm) excitation light irradiation to Submucosa, make tissue produce hyperfluorescence.If fluorescence runs into dysplastic focus (abnormal aggregation or the mucosa of such as superficial vein thicken), light reduces, and fluorescence dies down.This endoscopic system can convert these slight changes to color information, and the technicality between normal mucosa and focus is emphasized, for the pathological change of diagnostic organization provides foundation.
Chinese patent CN 103340601 A proposes a kind of multi-optical spectrum imaging system based on endoscope and method, the equipment that this patent proposes provides near-infrared and visible light source, and use many group filter plates to filter, thus obtain the multispectral image corresponding with optical filter.
The narrow-band spectrum imaging endoscope that above-mentioned Olympus proposes, autofluorescence imaging endoscope and patent CN 103340601 A propose " multi-optical spectrum imaging system based on endoscope " and usually comprise light source, for providing the illumination light of full spectral coverage in near-infrared to visible ray; Filter plate combines, and irradiates tested tissue for selecting the coupling light of narrower spectral coverage in illumination light to endoscope; Endoscope, takes and is testedly organized in the spectrum picture of specifying under spectral coverage illumination; Graphics processing unit, by tested be organized in various spectral coverage illumination light under spectrum picture carry out image co-registration and process, obtain tissue spectrum picture; And display unit, image display is carried out to above-mentioned image; These equipment can realize carrying out at body light spectrum image-forming in-vivo tissue to a certain extent.But still there is its limitation.
The common ground of above-mentioned several scheme is that the light source after utilizing wave plate after filtration to filter throws light on to tissue, to obtain the illumination spectra image corresponding with filter plate.Or use mono-colour laser as light source, to obtain the corresponding spectrum picture of laser wavelength.
The mode of this spectrum picture has larger limitation.In a set of equipment, the quantity of filter plate determines the spectral composition of the multispectral image of the tissue that can collect.The narrow-band spectrum imaging endoscope equipment of such as Olympus.This equipment has two groups and amounts to five kinds of filter plate: R (600nm ~ 700nm), G (500nm ~ 600nm), B (400nm ~ 500nm) filter plate group and Ga (540nm ~ 560nm), Ba (405nm ~ 415nm) filter plate group, and this equipment can only obtain two kinds of spectrum pictures of tissue.
In sum, current technical scheme, owing to relying on filter plate or mono-colour laser, can only obtain few several specific spectrum pictures of tissue.
Utility model content
For such scheme shortcoming, the purpose of this utility model is the selecting arrangement providing a kind of endoscope illumination spectra, can obtain any spectral coverage in near-infrared to visible spectrum simply and easily, for endoscope's light spectrum image-forming.
Another object of the present utility model is to provide the ultraphotic spectrum using above-mentioned selecting arrangement endoscopic imaging system, can obtain the spectrum picture of spectral coverage arbitrarily in tested tissue near-infrared to visible spectrum.
First object of the present utility model is realized by following technical measures: the selecting arrangement of a kind of endoscope illumination spectra, comprising:
Dispersion element, carries out dispersion for the visible light beam that will incide on dispersion element by the difference of wavelength, the angle of emergent light or position is distributed according to lambda1-wavelength;
Collecting lens, the focus of collecting lens is positioned at the incidence point of visible light beam and dispersion element;
Movable reflecting mirror, is controlled down to carry out motion in one dimension by drive circuit;
The light guide therefor of fujinon electronic video endoscope, for the illumination spectra of the input different-waveband that is coupled;
Each different wavelengths of light of dispersion element outgoing projects movable reflecting mirror after collecting lens, by the movement of movable reflecting mirror, each wavelength light is coupled to respectively the plane of incidence of the light guide therefor of fujinon electronic video endoscope.
Preferential, described dispersion element is reflecting grating.
Another object of the present utility model is realized by following technical measures: a kind of ultraphotic spectrum endoscopic imaging system, comprising: light source, for providing the illumination light of full spectral coverage in near-infrared to visible ray; The selecting arrangement of illumination spectra, specifies arbitrarily the coupling light of spectral coverage to irradiate tested tissue to endoscope for selecting in illumination light; Endoscope, takes and is testedly organized in the spectrum picture of specifying under spectral coverage illumination; Graphics processing unit, by tested be organized in various spectral coverage illumination light under spectrum picture carry out image co-registration and process, obtain tissue spectrum picture; And display unit, image display is carried out to above-mentioned image;
It is characterized in that the selecting arrangement of described illumination spectra comprises:
Dispersion element, carries out dispersion for the visible light beam that will incide on dispersion element by the difference of wavelength, the angle of emergent light or position is distributed according to lambda1-wavelength;
Collecting lens, the focus of collecting lens is positioned at the incidence point of visible light beam and dispersion element;
Movable reflecting mirror, is controlled down to carry out motion in one dimension by drive circuit;
The light guide therefor of fujinon electronic video endoscope, for the illumination spectra of the input different-waveband that is coupled;
Each different wavelengths of light of dispersion element outgoing projects movable reflecting mirror after collecting lens, by the movement of movable reflecting mirror, each wavelength light is coupled to respectively the plane of incidence of the light guide therefor of fujinon electronic video endoscope.
Preferential, described dispersion element is reflecting grating.
Preferential, described light source comprises: xenon lamp and collimating lens, and the illumination light that described xenon lamp sends is collimated into directional light output through collimating lens and projects on described dispersion element.
Further, described light source also comprises the iris for changing clear aperature size, and the directional light that described collimating lens is collimated into exports and projects on described dispersion element after iris.
Further, in described graphics processing unit, be provided with control module, regulate for the shooting of the driving of respectively movable reflecting mirror described in trigging control, endoscope, image procossing and the aperture of the diaphragm.
This utility model utilizes the chromatic dispersion principle of light, uses wavelength selection system simply, conveniently to select the wavelength irradiating light, obtains the illumination spectra of any spectral coverage in tested tissue near-infrared to visible spectrum in real time; Doctor according to the optical characteristics of the state of an illness of patient and pathological tissues, can select the spectrum picture needing shooting, realizes collection of illustrative plates unification, real time spectrum imaging to biological tissue in body; Realize the early diagnosis of some pathological change.Particularly the pathogeny of tumor and other diseases, clinical diagnosis, the state of an illness are detected and the research of curative effect evaluation significant.
Accompanying drawing explanation
Fig. 1 this utility model system principle composition frame chart;
The schematic diagram of different wave length is selected in Fig. 2 this utility model wavelength selection system.
Detailed description of the invention
If Fig. 1 is an example of the present utility model.As shown in Figure 1, the ultraphotic spectrum endoscopic imaging system of the present embodiment comprises: light supply apparatus 1, wavelength selection system 2, fujinon electronic video endoscope 3, image processor 4, display 5.
Wherein, light supply apparatus 1 is for providing illumination light.The illumination light that illuminator 1 provides, at near-infrared in visible spectrum, light radiation intensity is continuous distribution with frequency change.In the present embodiment, light supply apparatus 1 comprises: xenon lamp 7, and its effect sends illumination light; Collimating lens 8, is collimated into directional light by the illumination light that xenon lamp 7 sends; Iris 9, under control circuit controls, can change the size of clear aperature, thus realizes controlling to export illumination light intensity.
The effect of wavelength selection system 2 is, selects the light of specifying spectral coverage scope from illumination light, and by the plane of incidence of the convergence of rays of this spectral coverage to the light guide therefor 12 of fujinon electronic video endoscope 3.Wavelength selection system 2 comprises: dispersion element 9, collecting lens 10, movable reflecting mirror 11 and light guide therefor 12.Dispersion element 9 its act as and carry out dispersion by inciding the difference of the light beam on dispersing element 9 by wavelength, the angle of emergent light or position are distributed according to lambda1-wavelength; GR50-0603 reflecting grating that Thorlabs company produces can be used in the present embodiment as dispersion element.The front focus of collecting lens 10 is positioned at the incidence point of illumination light and dispersion element; Movable reflecting mirror 11 is between collecting lens 10 and light guide therefor 12; Position relationship between the movement position of movable reflecting mirror 11 and collecting lens 10, light guide therefor 12 meet specify that the light of spectral coverage scope is assembled through collecting lens 10, movable reflecting mirror 11 reflect after light focusing on the end face of light guide therefor 12.In the present embodiment, movable reflecting mirror does one dimension translational motion; The drive circuit of movable reflecting mirror can be use chip microcontroller.
Fig. 2 is the principle schematic that wavelength selection system 3 carries out specified wavelength selection.According to grating formula, spacing is the reflecting grating of d, and incident illumination is incident with the angle of incidence α relative to grating surface normal, m level emergent light relative to the angle of emergence θ of grating surface normal and the relation of lambda1-wavelength λ as follows:
d(sin(θ)-sin(α))＝mλ
Illumination light medium wavelength is λ
1be λ with wavelength
2light can with different angle outgoing after reflecting grating.Focus due to collecting lens 10 is positioned at the incidence point of illumination light and reflecting grating, wavelength X
1be λ with wavelength
2light after collecting lens, focus on different positions.If the focal length of collecting lens is f, wavelength X
1be λ with wavelength
2light through the distance, delta l of collecting lens post-concentration point be:
Δl＝f(tanθ
1-tanθ
2)
As shown in Figure 2, the diameter of the plane of incidence of light guide therefor 12 is a, in one of the states wavelength X
1light after movable reflecting mirror 11 reflects, converge to light guide therefor 12 center.If wavelength is λ
2light after collecting lens with wavelength X
1the distance, delta l of convergent point when being greater than 1/2a, then wavelength X
2light cannot enter light guide therefor 12.In another state, movable reflecting mirror moves right distance, delta l, then wavelength X
2convergence of rays to light guide therefor 12 center, and wavelength X
1light cannot enter light guide therefor 12.So, can, by controlling the position of movable reflecting mirror, the wavelength needed be selected to be coupled into light guide therefor 12.
As the shooting λ needed
1, λ
2. λ
nspectrum picture, specifically can select one and comprise dispersion λ
1, λ
2. λ
nthe reflecting grating of different-waveband light, reflecting mirror needs at one dimension translational motion n location point, and these different wave lengths and location point need the corresponding also stored record of prior adjustment in control module and transmitting mirror drive circuit.
Above-mentioned dispersion element also can adopt as transmission grating, dispersing prism, spectrophotometer, spectrogrph, acousto-optic deflection device or liquid crystal tunable filter etc., and the principle of these elements and above-mentioned reflecting grating are roughly the same.Movable reflecting mirror also can adopt control, and it rotates accommodation reflex angle, above-mentioned dispersion element is exported different wavelength and is coupled into light guide therefor.
Fujinon electronic video endoscope 3 effect is inserted in body cavity and takes the image information of intraluminal tissue, stored by image processor 4.
Image processor 4 effect stores the electronic image on imaging apparatus, and synthesized by the image be organized under a series of spectral illumination, obtains the spectrum picture of the high spectral resolution of tissue.
In above-mentioned graphics processing unit, control module is set, regulates for the shooting of the driving of respectively movable reflecting mirror described in trigging control, endoscope, image procossing and the aperture of the diaphragm.
The process of concrete cooperation control is as follows: the state of an illness of doctor according to patient and the optical signature of tissue, the shooting λ that setting needs
1, λ
2. λ
nspectrum picture.Control module sends control signal to drive circuit, makes movable reflecting mirror 11 move to position A, makes wavelength X
1coupling light enter light guide 12, and by light guide 12 and fujinon electronic video endoscope 4, to be irradiated in tested tissue.Fujinon electronic video endoscope 4 to be collected in tested tissue reflected light or to bring out fluorescence, is imaged onto imaging apparatus image planes, and is saved as λ by image processor 5
1image.Control module sends control signal to drive circuit, makes movable reflecting mirror 11 move to position B, makes wavelength X
2coupling light enter light guide 12, and by light guide 12 and fujinon electronic video endoscope 3, to be irradiated in tested tissue.Fujinon electronic video endoscope 3 to be collected in tested tissue reflected light or to bring out fluorescence, is imaged onto imaging apparatus image planes, and is saved as λ by image processor 4
2image.Circulation like this, obtains tested tissue one group of λ
1, λ
2. λ
nspectrum picture.This is organized Images uniting by image processor, obtains tested tissue at λ
1, λ
2. λ
nsynthetic spectrum image in spectrum.And shown by display 5.
This utility model does not limit to and above-mentioned detailed description of the invention; according to foregoing; according to ordinary technical knowledge and the customary means of this area; do not departing under this utility model above-mentioned basic fundamental thought prerequisite; this utility model can also make the equivalent modifications of other various ways, replacement or change, all drops among protection domain of the present utility model.
Claims (7)
1. a selecting arrangement for endoscope's illumination spectra, is characterized in that comprising:
Dispersion element, carries out dispersion for the visible light beam that will incide on dispersion element by the difference of wavelength, the angle of emergent light or position is distributed according to lambda1-wavelength;
Collecting lens, the focus of collecting lens is positioned at the incidence point of visible light beam and dispersion element;
Movable reflecting mirror, is controlled down to carry out motion in one dimension by drive circuit;
The light guide therefor of fujinon electronic video endoscope, for the illumination spectra of the input different-waveband that is coupled;
Each different wavelengths of light of dispersion element outgoing projects movable reflecting mirror after collecting lens, by the movement of movable reflecting mirror, each wavelength light is coupled to respectively the incident end face of the light guide therefor of fujinon electronic video endoscope.
2. the selecting arrangement of a kind of endoscope according to claim 1 illumination spectra, is characterized in that: described dispersion element is reflecting grating.
3. a ultraphotic spectrum endoscopic imaging system, comprising: light source, for providing the illumination light of full spectral coverage in near-infrared to visible ray; The selecting arrangement of illumination spectra, specifies arbitrarily the coupling light of spectral coverage to irradiate tested tissue to endoscope for selecting in illumination light; Endoscope, takes and is testedly organized in the spectrum picture of specifying under spectral coverage illumination; Graphics processing unit, by tested be organized in various spectral coverage illumination light under spectrum picture carry out image co-registration and process, obtain tissue spectrum picture; And display unit, image display is carried out to above-mentioned image;
It is characterized in that the selecting arrangement of described illumination spectra comprises:
Dispersion element, carries out dispersion for the visible light beam that will incide on dispersion element by the difference of wavelength, the angle of emergent light or position is distributed according to lambda1-wavelength;
Collecting lens, the focus of collecting lens is positioned at the incidence point of visible light beam and dispersion element;
Movable reflecting mirror, is controlled down to carry out motion in one dimension by drive circuit;
The light guide therefor of fujinon electronic video endoscope, for the illumination spectra of the input different-waveband that is coupled;
Each different wavelengths of light of dispersion element outgoing projects movable reflecting mirror after collecting lens, by the movement of movable reflecting mirror, each wavelength light is coupled to respectively the plane of incidence of the light guide therefor of fujinon electronic video endoscope.
4. a kind of ultraphotic spectrum endoscopic imaging system according to claim 3, is characterized in that: described dispersion element is reflecting grating.
5. a kind of ultraphotic spectrum endoscopic imaging system according to claim 3, it is characterized in that: described light source comprises: xenon lamp and collimating lens, the illumination light that described xenon lamp sends is collimated into directional light output through collimating lens and projects on described dispersion element.
6. a kind of ultraphotic spectrum endoscopic imaging system according to claim 5, it is characterized in that: described light source also comprises the iris for changing clear aperature size, the directional light that described collimating lens is collimated into exports and projects on described dispersion element after iris.
7. a kind of ultraphotic spectrum endoscopic imaging system according to claim 3, it is characterized in that: in described graphics processing unit, be provided with control module, regulate for the shooting of the driving of respectively movable reflecting mirror described in trigging control, endoscope, image procossing and the aperture of the diaphragm.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201420591311.5U CN204207717U (en) | 2014-10-13 | 2014-10-13 | Endoscope's illumination spectra selecting arrangement and ultraphotic spectrum endoscopic imaging system |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352216A (en) * | 2014-10-13 | 2015-02-18 | 佛山市南海区欧谱曼迪科技有限责任公司 | Endoscope illumination spectrum selecting device and hyperspectral endoscope imaging system |
| CN106840392A (en) * | 2015-12-03 | 2017-06-13 | 北京北方微电子基地设备工艺研究中心有限责任公司 | Help device, spectral signal system and the semiconductor equipment of spectral signal collection |
| CN109222865A (en) * | 2018-10-17 | 2019-01-18 | 卓外（上海）医疗电子科技有限公司 | A kind of multi-modality imaging endoscopic system |
| CN111601536A (en) * | 2017-12-27 | 2020-08-28 | 爱惜康有限责任公司 | Hyperspectral imaging in a light deficient environment |
-
2014
- 2014-10-13 CN CN201420591311.5U patent/CN204207717U/en not_active Withdrawn - After Issue
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352216A (en) * | 2014-10-13 | 2015-02-18 | 佛山市南海区欧谱曼迪科技有限责任公司 | Endoscope illumination spectrum selecting device and hyperspectral endoscope imaging system |
| CN106840392A (en) * | 2015-12-03 | 2017-06-13 | 北京北方微电子基地设备工艺研究中心有限责任公司 | Help device, spectral signal system and the semiconductor equipment of spectral signal collection |
| CN111601536A (en) * | 2017-12-27 | 2020-08-28 | 爱惜康有限责任公司 | Hyperspectral imaging in a light deficient environment |
| CN111601536B (en) * | 2017-12-27 | 2023-12-15 | 爱惜康有限责任公司 | Hyperspectral imaging in light deficient environments |
| CN109222865A (en) * | 2018-10-17 | 2019-01-18 | 卓外（上海）医疗电子科技有限公司 | A kind of multi-modality imaging endoscopic system |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| AV01 | Patent right actively abandoned |
Granted publication date: 20150318 Effective date of abandoning: 20160420 |
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| C25 | Abandonment of patent right or utility model to avoid double patenting |