CN203941176U - A kind of intelligent immunochromatographiassays assays device - Google Patents
A kind of intelligent immunochromatographiassays assays device Download PDFInfo
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- CN203941176U CN203941176U CN201420361000.XU CN201420361000U CN203941176U CN 203941176 U CN203941176 U CN 203941176U CN 201420361000 U CN201420361000 U CN 201420361000U CN 203941176 U CN203941176 U CN 203941176U
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- immunochromatographiassays assays
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- 238000003556 assay Methods 0.000 title claims abstract description 44
- 238000012360 testing method Methods 0.000 claims abstract description 44
- 239000004973 liquid crystal related substance Substances 0.000 claims abstract description 22
- 230000003993 interaction Effects 0.000 claims abstract description 14
- 238000007405 data analysis Methods 0.000 claims abstract description 10
- 238000001514 detection method Methods 0.000 claims abstract description 10
- 238000012545 processing Methods 0.000 claims abstract description 10
- 238000004891 communication Methods 0.000 claims description 15
- 238000005259 measurement Methods 0.000 claims description 13
- 239000003153 chemical reaction reagent Substances 0.000 claims description 12
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical group [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 6
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 235000012206 bottled water Nutrition 0.000 abstract description 2
- 239000002537 cosmetic Substances 0.000 abstract description 2
- 239000003651 drinking water Substances 0.000 abstract description 2
- 239000003814 drug Substances 0.000 abstract description 2
- 231100000614 poison Toxicity 0.000 abstract description 2
- 230000007096 poisonous effect Effects 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 10
- 238000011088 calibration curve Methods 0.000 description 8
- 239000013307 optical fiber Substances 0.000 description 4
- YJQZYXCXBBCEAQ-UHFFFAOYSA-N ractopamine Chemical compound C=1C=C(O)C=CC=1C(O)CNC(C)CCC1=CC=C(O)C=C1 YJQZYXCXBBCEAQ-UHFFFAOYSA-N 0.000 description 4
- 229940074095 ractopamine Drugs 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 229910052737 gold Inorganic materials 0.000 description 3
- 238000013459 approach Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 230000008676 import Effects 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- XQYZDYMELSJDRZ-UHFFFAOYSA-N papaverine Chemical compound C1=C(OC)C(OC)=CC=C1CC1=NC=CC2=CC(OC)=C(OC)C=C12 XQYZDYMELSJDRZ-UHFFFAOYSA-N 0.000 description 2
- 229930008281 A03AD01 - Papaverine Natural products 0.000 description 1
- 229930195730 Aflatoxin Natural products 0.000 description 1
- XWIYFDMXXLINPU-UHFFFAOYSA-N Aflatoxin G Chemical compound O=C1OCCC2=C1C(=O)OC1=C2C(OC)=CC2=C1C1C=COC1O2 XWIYFDMXXLINPU-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 229920000877 Melamine resin Polymers 0.000 description 1
- 239000004098 Tetracycline Substances 0.000 description 1
- 239000005409 aflatoxin Substances 0.000 description 1
- 239000002115 aflatoxin B1 Substances 0.000 description 1
- OQIQSTLJSLGHID-WNWIJWBNSA-N aflatoxin B1 Chemical compound C=1([C@@H]2C=CO[C@@H]2OC=1C=C(C1=2)OC)C=2OC(=O)C2=C1CCC2=O OQIQSTLJSLGHID-WNWIJWBNSA-N 0.000 description 1
- MJBWDEQAUQTVKK-IAGOWNOFSA-N aflatoxin M1 Chemical compound C=1([C@]2(O)C=CO[C@@H]2OC=1C=C(C1=2)OC)C=2OC(=O)C2=C1CCC2=O MJBWDEQAUQTVKK-IAGOWNOFSA-N 0.000 description 1
- 229930020125 aflatoxin-B1 Natural products 0.000 description 1
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 1
- 229940097572 chloromycetin Drugs 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- LINOMUASTDIRTM-QGRHZQQGSA-N deoxynivalenol Chemical compound C([C@@]12[C@@]3(C[C@@H](O)[C@H]1O[C@@H]1C=C(C([C@@H](O)[C@@]13CO)=O)C)C)O2 LINOMUASTDIRTM-QGRHZQQGSA-N 0.000 description 1
- FDZZZRQASAIRJF-UHFFFAOYSA-M malachite green Chemical compound [Cl-].C1=CC(N(C)C)=CC=C1C(C=1C=CC=CC=1)=C1C=CC(=[N+](C)C)C=C1 FDZZZRQASAIRJF-UHFFFAOYSA-M 0.000 description 1
- 229940107698 malachite green Drugs 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- JDSHMPZPIAZGSV-UHFFFAOYSA-N melamine Chemical compound NC1=NC(N)=NC(N)=N1 JDSHMPZPIAZGSV-UHFFFAOYSA-N 0.000 description 1
- 229940091868 melamine Drugs 0.000 description 1
- 229960001789 papaverine Drugs 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 229960002052 salbutamol Drugs 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 229940040944 tetracyclines Drugs 0.000 description 1
- MBMQEIFVQACCCH-UHFFFAOYSA-N trans-Zearalenon Natural products O=C1OC(C)CCCC(=O)CCCC=CC2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-UHFFFAOYSA-N 0.000 description 1
- LINOMUASTDIRTM-UHFFFAOYSA-N vomitoxin hydrate Natural products OCC12C(O)C(=O)C(C)=CC1OC1C(O)CC2(C)C11CO1 LINOMUASTDIRTM-UHFFFAOYSA-N 0.000 description 1
- MBMQEIFVQACCCH-QBODLPLBSA-N zearalenone Chemical compound O=C1O[C@@H](C)CCCC(=O)CCC\C=C\C2=CC(O)=CC(O)=C21 MBMQEIFVQACCCH-QBODLPLBSA-N 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a kind of intelligent immunochromatographiassays assays device, for the examination of some poisonous and harmful substances of food and medicine cosmetics and potable water.Comprise housing, human-computer interaction module, light-source system, image capture module, data analysis processing module and data upload module, wherein human-computer interaction module mainly comprises liquid crystal display touch screen and control circuit, on housing, be provided with liquid crystal display touch screen and power switch key, at housing right flank, be provided with pattern detection window, after housing, be provided with outlet, USB socket and network outlet, image capture module mainly comprises planar array type CCD camera.Owing to adopting planar array type CCD camera to solve the bulky problem of instrument, coordinate in addition upper computer software can realize the precise calibration of test card, solve the problem of testing result poor stability, can also carry out image acquisition, storage and reproduction to test zone in addition.
Description
Technical field
The utility model relates to a kind of intelligent immunochromatographiassays assays device, for the examination of some poisonous and harmful substances of food and medicine cosmetics and potable water.
Background technology
The method that instrument mainly adopts at present has optical fiber scanning method and linear array CCD scanning method.
Optical fiber scanning method is moved by driven by motor test strips, and Fibre Optical Sensor is scanned to p-wire from the background area of test strips.The incident light being sent by light emitting diode irradiates on test paper test section, and reflected light is delivered to photodetector via reception optical fiber transmission and converted photosignal output to, and electric signal size is corresponding with the size of test section reflective light intensity.The method need to drive Fibre Optical Sensor to scan by mechanical scanner, causes instrument volume large and heavy; And the in the situation that of low concentration, because intensity of reflected light variation is very faint, can cause measurement result poor stability.
Linear array CCD scanning method has solved that instrument volume in optical fiber scanning method is large, the poor problem of Measurement sensibility to a certain extent, but because linear CCD sensor can only gather a certain the photosignal on line, so still can cause the decline of measurement result stability, and measurement result can only show and reappear with the form of data, can not with the form of picture, show and reappear.
Utility model content
Large in order to overcome existing instrument volume, the problem that measurement result degree of stability is poor and measurement result can not show and reappear with picture form, the utility model provides a kind of intelligent immunochromatographiassays assays device, adopt planar array type CCD camera to solve the bulky problem of instrument, coordinate in addition upper computer software the utility model can realize the precise calibration of test card, solved the problem of testing result poor stability, due to what adopt in the utility model, it is planar array type CCD camera, so can carry out image acquisition to test zone, storage and reproduction.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, comprise housing, human-computer interaction module, light-source system, image capture module, data analysis processing module and data upload module, human-computer interaction module mainly comprises liquid crystal display touch screen and control circuit, light-source system mainly comprises LED lamp and visible ray can be provided, on housing, be provided with liquid crystal display touch screen and power switch key, at housing right flank, be provided with pattern detection window, after housing, be provided with outlet, USB socket and network outlet, image capture module mainly comprises planar array type CCD camera.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, also comprise test card, test card is colloidal gold test card and can inserts pattern detection window to top.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein planar array type CCD camera is arranged in a square formation and is connected into a device by a lot of photosensitive areas.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein human-computer interaction module can be worked by liquid crystal display touch screen and control circuit control power-supply system, image capture module, data analysis processing module and data upload module.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein liquid crystal display touch screen is LCDs, is also capacitive touch screen.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein liquid crystal display touch screen is provided with measurement, Reagent management, historical record and system four buttons is set, and by described measurement, Reagent management, historical record and system, four buttons is set and can enters respectively test item and select interface, Reagent management interface, historical record to check that interface and system arrange interface operation.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein data upload module comprises bluetooth communication, usb communication module and network interface communication module.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein the weight of device is 1kg, be of a size of 200mm * 150mm * 80mm, power is 3.6W, operating temperature range is 45 ℃ of-10 ℃ of < T <, optimum operation temperature is 25 ℃, and the coefficient of variation is CV≤3%.
The utility model is the analytical approach of disclosed a kind of intelligent immunochromatographiassays assays device also, and step is as follows:
The first step: test card calibration, test card calibration need to be carried out in conjunction with upper computer software, and concrete parameter is decided by reagent itself;
Second step: import calibration curve, the calibration curve generating in host computer is imported to a kind of intelligent immunochromatographiassays assays device by USB socket;
The 3rd step: operator is by the described liquid crystal display touch screen of described human-computer interaction module, and selecting needs the project detecting and determine and detect;
The 4th step: image capture module is received after sense command, can pass through planar array type CCD camera collection test card gray scale pictures;
The 5th step: data analysis processing module calculates corresponding testing result according to calibration curve and the photo collecting, and be presented on liquid crystal display touch screen detecting data;
The 6th step: project has detected rear operator and can select bluetooth communication, usb communication module and network interface communication module to upload detecting data by data upload module as required.
Beneficial effect
The disclosed a kind of intelligent immunochromatographiassays assays device of the utility model, adopts planar array type CCD camera, and volume is little, can carry out image acquisition, storage and reproduction to test zone, the data of collecting are like this more complete, so can realize the precise calibration of test card, testing result good stability.
Accompanying drawing explanation
Fig. 1 is a kind of stereographic map of intelligent immunochromatographiassays assays device.
Fig. 2 is a kind of right view of intelligent immunochromatographiassays assays device.
Fig. 3 is a kind of rear view of intelligent immunochromatographiassays assays device.
Fig. 4 is a kind of principle of work schematic diagram of intelligent immunochromatographiassays assays device.
Fig. 5 is a kind of analytical procedure schematic diagram of intelligent immunochromatographiassays assays device.
Embodiment
Below in conjunction with the drawings and specific embodiments, the utility model is described in further detail, but not as to restriction of the present utility model.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, comprise housing (01), human-computer interaction module (08), light-source system (09), image capture module (10), data analysis processing module (11) and data upload module (12), wherein human-computer interaction module (08) mainly comprises liquid crystal display touch screen (02) and control circuit (not shown), light-source system (09) mainly comprises LED lamp and visible ray can be provided, on housing (01), be provided with liquid crystal display touch screen (02) and power switch key (03), at housing (01) right flank, be provided with pattern detection window (04), at housing (01), be provided with outlet (05) below, USB socket (06) and network outlet (07), image capture module (10) mainly comprises planar array type CCD camera (not shown).
Utility model discloses a kind of intelligent immunochromatographiassays assays device, also comprises test card (13), and test card (13) is for colloidal gold test card and can insert pattern detection window (04) to top.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein image capture module (10) adopts planar array type CCD camera, and CCD can be divided into line array CCD and the large class of area array CCD two function.Line array CCD is divided into array by CCD internal electrode conventionally, and every group is called a phase, and applies same time clock.The required number of phases determines by CCD chip internal structure, and the different CCD of structure can meet the request for utilization of different occasions.Line array CCD has dividing of single raceway groove and double channel, and its photosensitive area is mos capacitance or photodiode structure, and production technology is relatively simple.It is comprised of photosensitive area array and shift register sweep circuit, and feature is that process information speed is fast, and peripheral circuit is simple, easily realize in real time and controlling, but obtaining information amount is little, can not process complicated image.The structure of area array CCD is more complex, and it is arranged in a square formation by a lot of photosensitive areas, and connects into a device with certain form, and obtaining information amount is large, can process complicated image.
Fig. 4 is a kind of principle of work schematic diagram of intelligent immunochromatographiassays assays device.Light-source system (09), image capture module (10), data analysis processing module (11) and data upload module (12) are controlled by human-computer interaction module (08) as we can see from the figure, more precisely, human-computer interaction module (08) can pass through liquid crystal display touch screen (02) and control circuit control light-source system (09), image capture module (10), data analysis processing module (11) and data upload module (12) work.
As shown in Figure 1, the utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein liquid crystal display touch screen (02) is LCDs, is also capacitive touch screen.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein liquid crystal display touch screen (02) is provided with measurement, Reagent management, historical record and system four buttons is set, and by described measurement, Reagent management, historical record and system, four buttons is set and can enters respectively test item and select interface, Reagent management interface, historical record to check that interface and system arrange interface operation.Test item selects interface to have " returning " " to refresh " " determining " three buttons, by these three buttons, can select corresponding test item to detect, after selected detailed programs, press " determining " key, interface will jump to measures interface, measure interface " measurements " " return to " " uploading " several buttons, use and can complete corresponding operating by these three buttons.In Reagent management interface, designed " returning " and " stopped using " and " importing " three buttons can be imported and delete calibration curve by these three buttons.At historical record, check in the page and can check testing result in the past by two buttons of " page up " " lower one page ", and can to testing result, operate by buttons such as " uploading " " deletions ".In system, interface is set, the parameters such as system time, automatic shutdown time can be set.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein data upload module (12) comprises bluetooth communication, usb communication module and network interface communication module.
The utility model discloses a kind of intelligent immunochromatographiassays assays device, wherein the weight of device is 1kg, be of a size of 200mm * 150mm * 80mm, power is 3.6W, operating temperature range is 45 ℃ of-10 ℃ of < T <, optimum operation temperature is 25 ℃, and the coefficient of variation is CV≤3%.
The utility model is the analytical approach of disclosed a kind of intelligent immunochromatographiassays assays device also, and as shown in Figure 5, step is as follows:
The first step: test card calibration, test card calibration need to be carried out in conjunction with upper computer software, and concrete parameter is decided by reagent itself;
Second step: import calibration curve, the calibration curve generating in host computer is imported to a kind of intelligent immunochromatographiassays assays device by USB socket;
The 3rd step: operator is by the described liquid crystal display touch screen of described human-computer interaction module, and selecting needs the project detecting and determine and detect;
The 4th step: image capture module is received after sense command, can pass through planar array type CCD camera collection test card gray scale pictures;
The 5th step: data analysis processing module calculates corresponding testing result according to calibration curve and the photo collecting, and be presented on liquid crystal display touch screen detecting data;
The 6th step: project has detected rear operator and can select bluetooth communication, usb communication module and network interface communication module to upload detecting data by data upload module as required.
Embodiment mono-
The disclosed a kind of intelligent immunochromatographiassays assays device of the utility model can detect following items: how residual total aflatoxin content, aflatoxin B1, aflatoxin M 1, zearalenone, vomitoxin, chloromycetin, sulfamido be, fluoquinolone, clenobuterol hydrochloride, salbutamol, Ractopamine, melamine, papaverine, malachite green, Tetracyclines.
The Ractopamine product of take is below elaborated as example, first carry out test card (13) calibration and calibration curve is imported by USB socket (06), on test card (13), add testing sample, wait for 10 minutes, test card (13) is inserted in well mode inwards in the groove of pattern detection window (04) to top, click the test button on liquid crystal display touch screen (02), this intelligent immunochromatographiassays assays device detects for 8 seconds reciprocal afterwards, and demonstrates testing result.Qualitative product can demonstrate the result of " feminine gender ", " positive ", " suspicious ", and quantitatively product can show detection sample concentration value.
The minimum detectability of this intelligent immunochromatographiassays assays device is gray scale 5, and naked eyes are judged as wireless, and naked eyes judge when wireless, and gold mark instrument gray scale result is below 5.This intelligent immunochromatographiassays assays device Supreme Procuratorate rising limit is gray scale 1200, and when detection line is aterrimus, gold mark instrument gray scale result is more than 1200.Take Ractopamine product as example, and while detecting feminine gender, product develops the color the most deeply, and gray scale is about 300, and while detecting 20ppb sample, gray scale is in 5.
Utilize Ractopamine product to detect the repeatability of gold mark instrument, same (detecting 5ppb sample), detects 10 times repeatedly, and result is as follows:
Table one
By table one, can be found out repeatability and the good stability of the disclosed a kind of intelligent immunochromatographiassays assays device of the utility model.
Claims (8)
1. an intelligent immunochromatographiassays assays device, it is characterized in that: comprise housing, human-computer interaction module, light-source system, image capture module, data analysis processing module and data upload module, described human-computer interaction module mainly comprises liquid crystal display touch screen and control circuit, described light-source system mainly comprises LED lamp and visible ray can be provided, on described housing, be provided with liquid crystal display touch screen and power switch key, at described housing right flank, be provided with pattern detection window, after described housing, be provided with outlet, USB socket and network outlet, described image capture module mainly comprises planar array type CCD camera.
2. a kind of intelligent immunochromatographiassays assays device according to claim 1, is characterized in that: described device also comprises test card, and described test card is colloidal gold test card and can inserts described pattern detection window to top.
3. a kind of intelligent immunochromatographiassays assays device according to claim 1, is characterized in that: described planar array type CCD camera is arranged in a square formation and is connected into a device by a lot of photosensitive areas.
4. a kind of intelligent immunochromatographiassays assays device according to claim 1, is characterized in that: described human-computer interaction module can be controlled described light-source system, described image capture module, described data analysis processing module and described data upload module by described liquid crystal display touch screen and described control circuit and work.
5. a kind of intelligent immunochromatographiassays assays device according to claim 1, is characterized in that: described liquid crystal display touch screen is LCDs, is also capacitive touch screen.
6. a kind of intelligent immunochromatographiassays assays device according to claim 1, it is characterized in that: described liquid crystal display touch screen is provided with measurement, Reagent management, historical record and system four buttons are set, by described measurement, Reagent management, historical record and system, four buttons are set and can enter respectively test item and select interface, Reagent management interface, historical record to check that interface and system arrange interface operation.
7. a kind of intelligent immunochromatographiassays assays device according to claim 1, is characterized in that: described data upload module comprises bluetooth communication, usb communication module and network interface communication module.
8. a kind of intelligent immunochromatographiassays assays device according to claim 1, it is characterized in that: the weight of described device is 1kg, be of a size of 200mm * 150mm * 80mm, power is 3.6W, operating temperature range is 45 ℃ of-10 ℃ of < T <, optimum operation temperature is 25 ℃, and the coefficient of variation is CV≤3%.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105223368A (en) * | 2014-07-02 | 2016-01-06 | 北京倍肯华业科技发展有限公司 | A kind of intelligent immunochromatographiassays assays device and analytical approach thereof |
CN105277680A (en) * | 2014-07-03 | 2016-01-27 | 北京倍肯华业科技发展有限公司 | Intelligentized immunochromatography and spectral analysis integrated device and analysis method therefor |
-
2014
- 2014-07-02 CN CN201420361000.XU patent/CN203941176U/en not_active Expired - Lifetime
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105223368A (en) * | 2014-07-02 | 2016-01-06 | 北京倍肯华业科技发展有限公司 | A kind of intelligent immunochromatographiassays assays device and analytical approach thereof |
CN105277680A (en) * | 2014-07-03 | 2016-01-27 | 北京倍肯华业科技发展有限公司 | Intelligentized immunochromatography and spectral analysis integrated device and analysis method therefor |
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Address after: Room 201, No. 1 Xingchang Road, Changping District, Beijing 102200 Patentee after: Medi Weidun (Beijing) Technology Development Co.,Ltd. Address before: Room 201, No. 1 Xingchang Road, Changping District, Beijing 102200 Patentee before: BEIJING BEIKEN HUAYE SCIENCE & TECHNOLOGY DEVELOPMENT CO.,LTD. |
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Granted publication date: 20141112 |