CN203838049U - Optical measurement device for measuring hemoglobin concentration - Google Patents
Optical measurement device for measuring hemoglobin concentration Download PDFInfo
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- CN203838049U CN203838049U CN201420136387.9U CN201420136387U CN203838049U CN 203838049 U CN203838049 U CN 203838049U CN 201420136387 U CN201420136387 U CN 201420136387U CN 203838049 U CN203838049 U CN 203838049U
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- silicon photocell
- hemoglobin concentration
- microplate
- control system
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- Investigating Or Analysing Materials By Optical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses an optical measurement device for measuring hemoglobin concentration. The optical measurement device comprises a body device, a printer and a scanning head. A measuring mechanism and a control system are arranged in the body device. The measuring mechanism comprises a base, a guide rail and a supporting frame, wherein the guide rail and the supporting frame are installed on the base. A sliding table is arranged on the guide rail, is in rotatable connection with the lower end of a damping wheel mechanism and is driven by a push-pull rod for bearing a microchip, a bicolor light-emitting diode is installed on the supporting frame, and a silicon photocell corresponding to the bicolor light-emitting diode is fixed on the base. When the push-pull rod is pushed to be in place, the bicolor light-emitting diode, an optical hole of the microchip and the silicon photocell are positioned on the same axis, the silicon photocell receives light penetrating the optical hole, and the light is converted into current signals to be sent to the control system. The optical measurement device is easy to operate, performs analysis quickly and accurately, is portable and low in cost and can be widely applied to the aspects of blood donor and athlete function assessment, clinical diagnosis and family health.
Description
Technical field
The utility model relates to a kind of apparatus for measuring concentration, specifically a kind of optical measuring apparatus of hemoglobin concentration.
Background technology
The spherical macromolecular compound that haemoglobin (Hemoglobin, Hb) is made up of protoheme and globin, its main Physiological Function is transport oxygen and carbon dioxide, and acidic materials are played to buffer action, the acid base equilibrium participating in body regulates.Adult's hemoglobin concentration normal range is at 11～16g/dl.The mensuration of haemoglobin is must look into project most widely used, at most clinically, is one of method checking anaemia.
Domestic mobile Blood Transfusion Services all adopts copper sulphate titrimetry to carry out hemoglobinometry at present, and hospital, inspection and quarantine mechanism etc. adopts the large-scale Biochemical Analyzer of import.The former exists and prepares voluntarily the shortcomings such as error is large, easy influenced by ambient temperature, and the latter's instrument is expensive, and testing cost is high.External conventional method of testing is kit and dry type biochemical analysis method, kit method needs large-scale Biochemical Analyzer, dry type biochemical analysis method product mainly contains German Reflotron IV type whole blood dry type Biochemical Analyzer and the SWELAB blood analyser of Sweden, what adopt is all wavelength ratio color methods, required blood sampling volume is larger, test duration is long, and cost is high.
Utility model content
It is a kind of simple to operate that the purpose of this utility model is to provide, and analyzes quick and precisely, and the optical measuring apparatus of portable and cheap hemoglobin concentration, to realize the nonhazardous of hemoglobin concentration in whole blood, portable, Accurate Measurement.
For achieving the above object, the utility model provides following technical scheme:
A kind of optical measuring apparatus of hemoglobin concentration, by body apparatus, printer and scanner head form, described body apparatus is built-in with measuring mechanism and control system, described measuring mechanism comprises base, and be arranged on guide rail and the bracing frame on base, on described guide rail, slide unit is installed, described slide unit and damping wheel mechanism lower end are rotationally connected, and slide unit drives by the pull bar for carrying microplate, between described damping wheel mechanism middle part and base, be provided with spring, damping wheel mechanism upper end and bracing frame are rotationally connected, dichromatic LED is installed on support frame as described above, on base, be fixed with the silicon photocell corresponding with dichromatic LED, in the time that pull bar is advancing to the position, the light eye of dichromatic LED, microplate, and silicon photocell is on same axis, silicon photocell receives and sees through the light that the dichromatic LED of light eye sends, and is converted to current signal and delivers to control system.
As further program of the utility model: described control system comprises the MSP430f149CPU being connected with printer and scanner head, described MSP430f149CPU is also connected with respectively real-time clock, Flash storer, position transducer, temperature sensor, liquid crystal display, touch controller, pulse control circuit, the input end of D/A converter and the output terminal of A/D converter, described position transducer is arranged on slide unit, described temperature sensor is arranged on the carrying microplate place of pull bar, described touch controller also connects touch-screen, the output terminal of described pulse control circuit and D/A converter is connected to the two ends of dichromatic LED, described silicon photocell connects the input end of A/D converter by signal processor.
As further program of the utility model: described microplate is medical disposable material, adopt that transparent polymeric material is injection-molded to be formed.
Compared with prior art, the beneficial effects of the utility model are: this analyzer only need inject disposable pastille microplate by a whole blood, then microplate are pushed to light sensation district and can within 30-60 second, realize the On-line rapid measurement of undiluted not haemolysis whole blood.Clinical testing shows, contrasts cyanmethemoglobin method correlativity and can reach 0.9836, and accuracy reaches 96.32%; This analyzer is simple to operate, analyzes quick and precisely, portable and cheap, can be widely used in the aspects such as blood donor, functional evaluation of athletes and clinical diagnosis and family health care.
Brief description of the drawings
Fig. 1 is the one-piece construction schematic diagram of the optical measuring apparatus of hemoglobin concentration;
Fig. 2 is the structural representation of measuring mechanism in the optical measuring apparatus of hemoglobin concentration;
Fig. 3 is the structural representation of microplate in the optical measuring apparatus of hemoglobin concentration;
Fig. 4 is the theory diagram of control system in the optical measuring apparatus of hemoglobin concentration;
Fig. 5 is the evaluation schematic diagram of the optical measuring apparatus of hemoglobin concentration.
Embodiment
Below in conjunction with the accompanying drawing in the utility model embodiment, the technical scheme in the utility model embodiment is clearly and completely described, obviously, described embodiment is only the utility model part embodiment, instead of whole embodiment.Based on the embodiment in the utility model, those of ordinary skill in the art are not making the every other embodiment obtaining under creative work prerequisite, all belong to the scope of the utility model protection.
Refer to Fig. 1, a kind of optical measuring apparatus of hemoglobin concentration, is made up of body apparatus 10, printer 20 and scanner head 30, and described body apparatus 10 is built-in with measuring mechanism and control system.
Refer to Fig. 2, described measuring mechanism comprises base 5, and be arranged on guide rail 8 and the bracing frame 9 on base 5, on described guide rail 8, slide unit 4 is installed, described slide unit 4 is rotationally connected with damping wheel mechanism 3 lower ends, and slide unit 4 drives by the pull bar 1 for carrying microplate 11, between described damping wheel mechanism 3 middle parts and base 5, be provided with spring 6, damping wheel mechanism 3 upper ends and bracing frame 9 are rotationally connected, dichromatic LED 2 is installed on support frame as described above 9, on base 5, is fixed with the silicon photocell corresponding with dichromatic LED 27.The pull bar 1 of described carrying microplate 11 slides on guide rail 8 by slide unit 4, after pull bar 1 is pulled out by operator, can place or change microplate 11; Touch pull bar 1, at effect lower push-pull bar 1 automatic retraction of spring 6; For avoiding pull bar 1 and rear end thrust mechanism generation sharp impacts, adopt damping wheel mechanism.In the time that pull bar 1 is advancing to the position, the light eye 111(of dichromatic LED 2, microplate 11 refers to Fig. 3), and silicon photocell 7 is on same axis, silicon photocell 7 receives and sees through the light that the dichromatic LED of light eye 111 sends, and is converted to current signal and delivers to control system.
Refer to Fig. 4, described control system comprises the MSP430f149CPU being connected with printer 20 and scanner head 30, described MSP430f149CPU is also connected with respectively real-time clock, Flash storer, position transducer, temperature sensor, liquid crystal display, touch controller, pulse control circuit, the input end of D/A converter and the output terminal of A/D converter, described position transducer is arranged on slide unit 4, described temperature sensor is arranged on carrying microplate 11 places of pull bar 1, described touch controller also connects touch-screen, the output terminal of described pulse control circuit and D/A converter is connected to the two ends of dichromatic LED 2, described silicon photocell 7 connects the input end of A/D converter by signal processor.Described control system is utilized function and the peripheral expansion circuit of MSP430f149CPU self, realizes detection that dual wavelength detects control, the silicon photocell signal of light, the temperature drift compensation control with touch-screen.The dichromatic LED adopting due to dichromatic LED has temperature drift characteristic, and the variation of system temperature will cause the variation of light intensity, thereby affects test result, and for this reason, control system has configured temperature and floated from eliminating circuit.
Described microplate is medical disposable material main in hemoglobin determinator system, adopts that transparent polymeric material is injection-molded forms.Its of paramount importance part is one can supply the lumen area of optical measurement, lumen wall solidifies the chemical reaction medicament of specified mix, tube chamber design volume is 10 μ l, two parallel plane designed distance is 0.15mm ± 5%, and this scheme can be guaranteed to meet quantitative measurment demand by the light intensity of microplate measured zone and error.In addition, fill difficulty and filling extent difference for the capillary that overcomes cavity volume, in advance cavity volume has been carried out to hydrophilic treatment, make its surface there is water wettability.
Test experiments: tested object is whole blood, test condition is room temperature condition, utilize cyanohemoglobin method and the utility model of widely accreditation to carry out the measurement of hemoglobin concentration, evaluate schematic diagram as shown in Figure 5, from the data in figure, the test value of Hb has good linear relationship within the scope of 8.0-16, when sample number n=50, both related coefficients reach 0.9836, and accuracy reaches 96.32%.This tester adopts disposable formula microplate to test, and has realized the interior quantitative measurment to hemoglobin concentration in whole blood 30-60 second, and precision reaches 0.1g/dl.With respect at present on the market for the large-scale Biochemical Analyzer of hemoglobin testing concentration determination, this tester be easy to carry and precision higher, so be with a wide range of applications in mobile Blood Transfusion Services, to sportsman's Site Detection and clinical medicine.
To those skilled in the art, obviously the utility model is not limited to the details of above-mentioned example embodiment, and in the situation that not deviating from spirit of the present utility model or essential characteristic, can realize the utility model with other concrete form.Therefore, no matter from which point, all should regard embodiment as exemplary, and be nonrestrictive, scope of the present utility model is limited by claims instead of above-mentioned explanation, is therefore intended to all changes that drop in the implication and the scope that are equal to important document of claim to include in the utility model.Any Reference numeral in claim should be considered as limiting related claim.
In addition, be to be understood that, although this instructions is described according to embodiment, but be not that each embodiment only comprises an independently technical scheme, this narrating mode of instructions is only for clarity sake, those skilled in the art should make instructions as a whole, and the technical scheme in each embodiment also can, through appropriately combined, form other embodiments that it will be appreciated by those skilled in the art that.
Claims (3)
1. the optical measuring apparatus of a hemoglobin concentration, by body apparatus, printer and scanner head form, described body apparatus is built-in with measuring mechanism and control system, it is characterized in that, described measuring mechanism comprises base, and be arranged on guide rail and the bracing frame on base, on described guide rail, slide unit is installed, described slide unit and damping wheel mechanism lower end are rotationally connected, and slide unit drives by the pull bar for carrying microplate, between described damping wheel mechanism middle part and base, be provided with spring, damping wheel mechanism upper end and bracing frame are rotationally connected, dichromatic LED is installed on support frame as described above, on base, be fixed with the silicon photocell corresponding with dichromatic LED, in the time that pull bar is advancing to the position, the light eye of dichromatic LED, microplate, and silicon photocell is on same axis, silicon photocell receives and sees through the light that the dichromatic LED of light eye sends, and is converted to current signal and delivers to control system.
2. the optical measuring apparatus of hemoglobin concentration according to claim 1, it is characterized in that, described control system comprises the MSP430f149CPU being connected with printer and scanner head, described MSP430f149CPU is also connected with respectively real-time clock, Flash storer, position transducer, temperature sensor, liquid crystal display, touch controller, pulse control circuit, the input end of D/A converter and the output terminal of A/D converter, described position transducer is arranged on slide unit, described temperature sensor is arranged on the carrying microplate place of pull bar, described touch controller also connects touch-screen, the output terminal of described pulse control circuit and D/A converter is connected to the two ends of dichromatic LED, described silicon photocell connects the input end of A/D converter by signal processor.
3. the optical measuring apparatus of hemoglobin concentration according to claim 1, is characterized in that, described microplate is medical disposable material, adopts that transparent polymeric material is injection-molded forms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420136387.9U CN203838049U (en) | 2014-03-25 | 2014-03-25 | Optical measurement device for measuring hemoglobin concentration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201420136387.9U CN203838049U (en) | 2014-03-25 | 2014-03-25 | Optical measurement device for measuring hemoglobin concentration |
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| Publication Number | Publication Date |
|---|---|
| CN203838049U true CN203838049U (en) | 2014-09-17 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201420136387.9U Expired - Fee Related CN203838049U (en) | 2014-03-25 | 2014-03-25 | Optical measurement device for measuring hemoglobin concentration |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109557294A (en) * | 2018-12-12 | 2019-04-02 | 南京京顿医疗器械有限公司 | Hemoglobin analyser |
-
2014
- 2014-03-25 CN CN201420136387.9U patent/CN203838049U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109557294A (en) * | 2018-12-12 | 2019-04-02 | 南京京顿医疗器械有限公司 | Hemoglobin analyser |
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| Date | Code | Title | Description |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140917 Termination date: 20150325 |
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| EXPY | Termination of patent right or utility model |