CN203332650U - Freeze-drying tray for freeze-dried tablets and packaging system component - Google Patents

Freeze-drying tray for freeze-dried tablets and packaging system component Download PDF

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Publication number
CN203332650U
CN203332650U CN2013200238646U CN201320023864U CN203332650U CN 203332650 U CN203332650 U CN 203332650U CN 2013200238646 U CN2013200238646 U CN 2013200238646U CN 201320023864 U CN201320023864 U CN 201320023864U CN 203332650 U CN203332650 U CN 203332650U
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CN
China
Prior art keywords
freeze
medicine
packaging
drying
bubble
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Expired - Fee Related
Application number
CN2013200238646U
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Chinese (zh)
Inventor
汪六一
汪金灿
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Hainan Weikang Pharmaceutical Qianshan Co Ltd
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Hainan Weikang Pharmaceutical Qianshan Co Ltd
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Priority to CN2013200238646U priority Critical patent/CN203332650U/en
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Publication of CN203332650U publication Critical patent/CN203332650U/en
Anticipated expiration legal-status Critical
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Abstract

The utility model provides a freeze-drying tray for freeze-dried tablets and a packaging system component, and relates to the technical field of medicine production and packaging. The freeze-drying tray comprises a lower tray body and an upper cover disk. The lower tray body is formed by a plurality of medicine containing bowels which are connected together through a connecting plate, the upper cover disk is formed by a plurality of medicine covering bowels which are connected together through a connecting plate, and exhaust holes are evenly and annularly formed in the circumferential walls of the medicine covering bowels. The packaging system component comprises medicine packaging inner boxes which are composed of the medicine covering bowels and the medicine containing bowels, bubble cap packaging plates and an aluminum foil seal film. The medicine packaging inner boxes are arranged inside medicine containing bubble caps of the bubble cap packaging plates, and the aluminum foil seal film is attached on one side of a bubble cap opening of each bubble cap packaging plate in a sealing mode. The freeze-drying tray for the freeze-dried tablets and the packaging system component are simple and reasonable in structural design, simplify traditional processes of traditional freeze-drying tablet freeze drying and packaging, enable production technological process to be more reasonable, are simple and convenient to operate, enable the production efficiency to be improved obviously, and are suitable for mass industrial production.

Description

Freeze-drying pallet and packaging system assembly for the freeze-drying sheet
Technical field:
The utility model relates to pharmaceutical production packing technique field, relates in particular to freeze-drying pallet and packaging system assembly for a kind of freeze-drying sheet.
Background technology:
In recent years, drug manufacturer has been widely used protruding blister pack and has been shaped and packing for medicinal tablet, and these protruding blister packs generally are comprised of protruding bubble shape sheet or protruding bubble shape film and cover plate.Protruding bubble shape sheet comprises some depressions of holding single medicament.In the standard method for the manufacture of the lyophilisation tablet, aqueous single medicament is introduced in freezing environment, and in this environment, medicament runs into low temperature so that they are freezing.Afterwards, more protruding bubble shape sheet is moved into to freeze-dryer, at this, ice is because distillation is removed.When lyophilisation completes, protruding bubble shape sheet takes out and uses the cover plate of a viscosity to cover in dry house, and this cover plate is sealed in the medicament of solid in each depression.This is a kind of known method for the manufacture of the lyophilisation tablet.
Yet the method has some weak points.At first, protruding bubble shape sheet is generally used the polymeric material manufacture, and it can make after a while moisture infiltrate in protruding blister pack and reach the stored medicament in the inside.For addressing this problem, developed some protruding bubble shape sheets, in these protruding bubble shape sheets, one deck aluminium lamination is pressed between two polymeric layers.The existence of aluminium lamination has prevented that moisture from infiltrating protruding blister pack, but it has brought again Second Problem.That is, in refrigerating process, when running into temperature traverse, traditional aluminium/polymeric layer rolled-up stock is because the difference of this laminate opposite layer on het expansion or shrinkage degree will be tending towards curling.This causes difficulty while just making them use in refrigerating process, because flowing product may flow out easily from formed depression.Unique terms of settlement is to use weight on the limit of laminate, in order to make them keep enough putting down.But such way is unpractiaca in large batch of manufacture work the time, and may disturb refrigerating process.
Also has a kind of improved method for the manufacture of the lyophilisation formulation in the protruding blister pack of aluminium (Zydis method).Medicament is introduced in the depression of protruding bubble shape sheet as a kind of liquid.Protruding bubble shape sheet comprises the interlayer of a sealing between the first and second skins, and each skin has in fact same whole thermal expansion coefficient, although it has solved the curling problem of protruding bubble shape sheet, but also there is medicament risk of the moisture absorption in contaminated and packaging process when lyophilisation, because liquid exposes all the time in freezing dry process, and dried medicament seals after can only taking out freeze drying box.
Therefore, this has a kind of curling problem that can be avoided protruding bubble shape sheet with regard to needs, again can be when the medicament lyophilisation, liquid is not contaminated, and can be in freeze drying box after the medicament moulding sealing and without the freeze-drying apparatus of moisture absorption risk fully.
The utility model content:
Technical problem to be solved in the utility model is to overcome the defect of prior art, freeze-drying pallet and packaging system assembly for a kind of freeze-drying sheet is provided, this system component has been simplified the traditional program of conventional freeze dry plate freeze-drying, packing, make the technological process of production more reasonable, production efficiency is improved significantly.
Technical problem to be solved in the utility model realizes by the following technical solutions:
Freeze-drying pallet and packaging system assembly for the freeze-drying sheet, it is characterized in that: described freeze-drying pallet comprises lower tray and upper cover plate, lower tray is linked together and forms by connecting plate by a plurality of Sheng medicine bowls, described upper cover plate is linked together and forms by connecting plate by a plurality of lid medicine bowls, and on described lid medicine bowl circle wall, uniform ring is provided with exhaust hole; During use, the medicine of freeze-drying moulding does not join in each Sheng medicine bowl of lower tray, then cover upper cover plate, each lid medicine bowl of upper cover plate is all covered on the Sheng medicine bowl of lower tray, lid medicine bowl only covers half into Sheng medicine bowl, the exhaust hole that makes to cover on the medicine bowl keeps unimpeded, finally send into lyophilisation in freeze dryer, steam in medicine can be discharged by the exhaust hole covered on the medicine bowl, after freeze-drying process finishes, lid medicine bowl on upper cover plate and the Sheng medicine bowl on lower tray cover fully, and now, the exhaust hole on lid medicine bowl is contained medicine bowl wall and blocked closure.Subsequently, in a plurality of drug packages that consist of Sheng medicine bowl and lid medicine bowl that are integrally connected, housing unit is divided into single drug package inner box by special-purpose cutting equipment, is finally packed.
Described packaging system assembly comprises by lid medicine bowl and contains drug package inner box, bubble package tray and the foil sealing film that the medicine bowl forms, described drug package inner box is placed in the Sheng medicine bubble-cap of bubble package tray, and described foil sealing film gluing, sealing is in bubble-cap mouth one side of bubble package tray; Single drug package inner box after cutting apart is put into respectively each bubble-cap of bubble package tray, then by getting final product after the encapsulation of foil sealing film.
Arrange or do not arrange handle on described lid medicine bowl circle wall.
Described exhaust hole is manhole, or is rule or fitfull polygon through hole.
The utility model structure design advantages of simple, simplified the traditional program of the freeze-drying of conventional freeze dry plate, packing, makes the technological process of production more reasonable, simple to operation, and production efficiency is improved significantly, and is applicable to mass industrialized production.
The accompanying drawing explanation:
Fig. 1 is the schematic diagram that lower tray and upper cover plate partly cover;
Fig. 2 is the schematic diagram that lower tray and upper cover plate cover entirely;
The structural representation that Fig. 3 is drug package inner box with handles;
The structural representation that Fig. 4 is drug package inner box not with handles;
The structural representation that Fig. 5 is the packaging system assembly.
The specific embodiment:
For technological means, creation characteristic that the utility model is realized, reach purpose and effect is easy to understand, below in conjunction with concrete diagram, further set forth the utility model.
As Figure 1-5, freeze-drying pallet and packaging system assembly for the freeze-drying sheet, the freeze-drying pallet comprises lower tray 1 and upper cover plate 2, lower tray 1 is linked together and forms by connecting plate 21 by a plurality of Sheng medicine bowls 31, upper cover plate 2 is linked together and forms by connecting plate 21 by a plurality of lid medicine bowls 33, and on lid medicine bowl 33 circle wall, uniform ring is provided with exhaust hole 34, during use, the medicine of freeze-drying moulding does not join in each Sheng medicine bowl 31 of lower tray 1, then cover upper cover plate 2, each lid medicine bowl 33 of upper cover plate 2 is all covered on the Sheng medicine bowl 31 of lower tray 1, 33 half that cover into Sheng medicine bowl 31 of lid medicine bowl, the exhaust hole 34 that makes to cover on medicine bowl 33 keeps unimpeded, finally send into lyophilisation in freeze dryer, steam in medicine can be discharged by the exhaust hole 34 covered on medicine bowl 33, after freeze-drying process finishes, lid medicine bowl 33 on upper cover plate 2 covers fully with the Sheng medicine bowl 31 on lower tray 1, now, exhaust hole 34 on lid medicine bowl 33 is contained medicine bowl wall and is blocked closure.Subsequently, in a plurality of drug packages that consist of Sheng medicine bowl 31 and lid medicine bowl 33 that are integrally connected, housing unit is divided into single drug package inner box 3 by special-purpose cutting equipment, is finally packed.
The packaging system assembly comprises by lid medicine bowl 33 and contains drug package inner box 3, bubble package tray 5 and the foil sealing film 4 that medicine bowl 31 forms, described drug package inner box 3 is placed in the Sheng medicine bubble-cap 51 of bubble package tray 5, and foil sealing film 4 gluing, sealings are in bubble-cap mouth one side of bubble package tray 5; Single drug package inner box 3 after cutting apart is put into respectively each Sheng medicine bubble-cap 51 of bubble package tray 5, then by getting final product after 4 encapsulation of foil sealing film.
As shown in Figure 3, on the circle wall of lid medicine bowl 33, handle 32 is set.
As shown in Figure 4, on the circle wall of lid medicine bowl 33, handle is not set.
Exhaust hole 34 or be manhole, or be rule or fitfull polygon through hole.
Above demonstration and described groundwork of the present utility model, principal character and advantage of the present utility model.The technical personnel of the industry should be understood; the utility model is not restricted to the described embodiments; that in above-described embodiment and specification sheets, describes just illustrates principle of the present utility model; under the prerequisite that does not break away from the utility model spirit and scope; the utility model also has various changes and modifications, and these changes and improvements all fall in claimed the utility model scope.The claimed scope of the utility model is defined by appending claims and equivalent thereof.

Claims (4)

1. a freeze-drying sheet freeze-drying pallet, it is characterized in that: described freeze-drying pallet comprises lower tray and upper cover plate, lower tray is linked together and forms by connecting plate by a plurality of Sheng medicine bowls, described upper cover plate is linked together and forms by connecting plate by a plurality of lid medicine bowls, and on described lid medicine bowl circle wall, uniform ring is provided with exhaust hole.
2. one kind comprises the described Sheng medicine of claim 1 bowl and the packaging system assembly that covers the medicine bowl, it is characterized in that: described packaging system assembly comprises by lid medicine bowl and contains drug package inner box, bubble package tray and the foil sealing film that the medicine bowl forms, described drug package inner box is placed in the Sheng medicine bubble-cap of bubble package tray, and described foil sealing film gluing, sealing is in bubble-cap mouth one side of bubble package tray.
3. packaging system assembly according to claim 2, is characterized in that: arrange or do not arrange handle on described lid medicine bowl circle wall.
4. freeze-drying sheet freeze-drying pallet according to claim 1, it is characterized in that: described exhaust hole is manhole or polygon through hole.
CN2013200238646U 2013-01-17 2013-01-17 Freeze-drying tray for freeze-dried tablets and packaging system component Expired - Fee Related CN203332650U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2013200238646U CN203332650U (en) 2013-01-17 2013-01-17 Freeze-drying tray for freeze-dried tablets and packaging system component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2013200238646U CN203332650U (en) 2013-01-17 2013-01-17 Freeze-drying tray for freeze-dried tablets and packaging system component

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CN203332650U true CN203332650U (en) 2013-12-11

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105806080A (en) * 2014-12-30 2016-07-27 江苏万邦生化医药股份有限公司 Freeze-drying disc for freeze dryer
CN115997919A (en) * 2023-03-10 2023-04-25 云南康嘉农副产品加工有限公司 Preparation method of freeze-dried tricholoma matsutake

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105806080A (en) * 2014-12-30 2016-07-27 江苏万邦生化医药股份有限公司 Freeze-drying disc for freeze dryer
CN105806080B (en) * 2014-12-30 2019-03-19 江苏万邦生化医药集团有限责任公司 A kind of lyophilized plate of freeze dryer
CN115997919A (en) * 2023-03-10 2023-04-25 云南康嘉农副产品加工有限公司 Preparation method of freeze-dried tricholoma matsutake

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20131211

Termination date: 20200117

CF01 Termination of patent right due to non-payment of annual fee