CN203249859U - Detection pool, sample introduction detecting system and urine analysis instrument - Google Patents
Detection pool, sample introduction detecting system and urine analysis instrument Download PDFInfo
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- CN203249859U CN203249859U CN 201220536142 CN201220536142U CN203249859U CN 203249859 U CN203249859 U CN 203249859U CN 201220536142 CN201220536142 CN 201220536142 CN 201220536142 U CN201220536142 U CN 201220536142U CN 203249859 U CN203249859 U CN 203249859U
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- solenoid valve
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Abstract
The invention discloses a detection pool, a sample introduction positioning and detecting system and a urine analysis instrument provided with the detection pool and the sample introduction positioning and detecting system. The urine analysis instrument comprises a microscope, an objective table arranged on the microscope, a driving component controlling the objective table to move, a positioning mark capable of imaging through the microscope, as well as a liquid feeding pipe, the detection pool, a liquid discharge pipe, a first electromagnetic valve arranged on the liquid feeding pipe and a second electromagnetic valve arranged on the liquid discharge pipe, which are connected sequentially, wherein the detection pool is arranged on the objective table; and the liquid feeding pipe and the liquid discharge pipe are communicated with the detection pool respectively. The positioning mark is arranged and used as a reference for focusing, the auto-focusing by the instrument is adopted instead of manual focusing, so that the analysis speed of the instrument is improved, and the automation degree of the instrument is greatly improved; and meanwhile, a sample can be accurately controlled on the focal plane of the microscope, so that a clear sample picture can be shot by the microscope, and the testing result is more accurate.
Description
Technical field
The utility model relates to Urine Analyzer, particularly the detection cell of Urine Analyzer, sample detection system.
Background technology
In the existing Urine Analyzer, the micro-imaging system all focuses apart from form, all be since a fixing optocoupler position that resets, the fixing step number (focus controlling parameter) of stepper motor operation realizes to the micro objective focal plane position, be subjected to the Accuracy of environment temperature and machine driven system, focal length variations very easily occurs, cause microscope to be taken pictures unintelligible, and then the impact analysis result.In this case, mainly rely on device operator manual modification focus controlling parameter to realize, this situation has increased the difficulty of operator's manually-operated focusing, and analysis speed is slow, can not satisfy the user demand of automatical analysis instrument.
Summary of the invention
The problem that the application will solve is, proposes a kind of detection cell, sample detection system and Urine Analyzer, is convenient to automatic focusing, makes testing result more accurate.
First aspect according to the application, a kind of Urine Analyzer is proposed, comprise microscope, be arranged on objective table on the microscope, control stage movement driven unit, can be by the telltale mark of microscope imaging, also comprise successively the feed tube, detection cell, the discharging tube that connect, be arranged on the first solenoid valve on the feed liquor pipeline, be arranged on the second solenoid valve on the drain line, described detection cell is arranged on the objective table, and described feed tube and described discharging tube are communicated with described detection cell respectively.
According to the application second aspect, a kind of Urine Analyzer detection cell is proposed, detection cell pond body, be arranged at least one test chamber on the body of detection cell pond, in the transparent cover on the top, chamber of described test chamber, described transparent cover or described test chamber bottom are provided with telltale mark.
The third aspect according to the application, a kind of Urine Analyzer sample detection system is proposed, comprise above-mentioned detection cell, also comprise feed tube, discharging tube, be arranged on the first solenoid valve on the feed liquor pipeline, be arranged on the described feed tube of the second solenoid valve on the drain line, described detection cell, discharging tube connect successively, and described feed tube and described discharging tube are communicated with the test chamber of described detection cell respectively.
Description of drawings
Fig. 1 is Urine Analyzer microscope principle schematic;
Fig. 2 is detection cell schematic diagram among a kind of embodiment of the application;
Fig. 3 be among a kind of embodiment of the application sample focal plane and grid silk-screen focal plane concern schematic diagram;
Fig. 4 is sample introduction position detecting system schematic diagram among a kind of embodiment of the application;
Fig. 5 is feed tube, drain pipe and detection cell connection diagram among a kind of embodiment of the application.
Embodiment
By reference to the accompanying drawings the application is described in further detail below by embodiment.
Urine Analyzer mainly comprises microscope, objective table is arranged on the microscope, detection cell is arranged on the objective table, the driven by motor stage movement realizes microscope is focused, detection cell is used for holding urine specimen, described detection cell connects respectively feed tube and discharging tube, seals sample by the solenoid valve that is arranged on feed tube and the discharging tube.Concrete, before the detection cell feed liquor, the first solenoid valve on the feed liquor pipeline is opened, and the second solenoid valve on the drain line is also opened simultaneously, and when detection cell was filled urine specimen, the first solenoid valve and the second solenoid valve were closed simultaneously.Then by microscope sample is carried out imaging, detected image is provided, finally obtain analysis result.The feed liquor pipeline refers to the formed liquid line of feed tube, and drain line refers to the formed liquid line of discharging tube.
The utility model provides a kind of Urine Analyzer, comprise microscope, be arranged on objective table on the microscope, control stage movement driven unit, can be by the telltale mark of microscope imaging, also comprise successively the feed tube, detection cell, the discharging tube that connect, be arranged on the first solenoid valve on the feed liquor pipeline, be arranged on the second solenoid valve on the drain line, described detection cell is arranged on the objective table, and described feed tube and described discharging tube are communicated with described detection cell respectively.This driven unit can motor, such as stepper motor.
Detection cell comprises detection cell pond body, is arranged at least one test chamber on the body of detection cell pond, the transparent cover of pushing up in the chamber of test chamber, and feed tube and discharging tube are communicated with described test chamber respectively.Described telltale mark arranges on the objective table, on the objective table table top such as objective table, can be arranged on the center section of objective table table top, also can be arranged on the edge of objective table table top; Can also be arranged on the detection cell, such as being arranged on the transparent cover, also can be arranged on the test chamber bottom; Can certainly be arranged on other assemblies, such as the detection cell fixation kit in fixed test pond, as long as microscopes is to this telltale mark imaging.Preferably be arranged on two ends on the transparent cover, avoid the tested sample zone, thereby imaging obtains the image planes of better tested sample.
Owing to being provided with telltale mark, focus as a reference by telltale mark, need not manually focus, but instrument focuses automatically, improved the analysis speed of instrument, the automaticity of instrument is improved greatly.Simultaneously, can accurately control sample on the microscope focal plane, make microscopes photograph clearly sample photo, make testing result more accurate.
In a kind of embodiment, as shown in Figure 1, Urine Analyzer comprises microscope 6, be arranged on the objective table 601 on the microscope 6, the motor 7 of control stage movement, feed tube, detection cell 1, discharging tube connects successively, also comprise the first solenoid valve (not marking among the figure) that is arranged on the feed liquor pipeline, be arranged on the second solenoid valve (not marking among the figure) on the drain line, detection cell 1 is arranged on objective table 601 table tops, detection cell 1 comprises detection cell pond body, be arranged at least one test chamber (not marking among the figure) on the body of detection cell pond, be used for holding urine specimen, the transparent cover of pushing up in the chamber of test chamber, be used for the sealing urine specimen, feed tube and discharging tube are communicated with test chamber respectively, are provided with telltale mark in transparent cover.
Owing to being provided with telltale mark in transparent cover, focus as a reference by telltale mark, need not manually focus, but instrument focuses automatically, improved the analysis speed of instrument, the automaticity of instrument is improved greatly.Simultaneously, can accurately control sample on the microscope focal plane, make microscopes photograph clearly sample photo, make testing result more accurate.
Further, also comprise the first sensor (not marking among the figure) and the second sensor (not marking among the figure) that have or not for detection of liquid, first sensor is on the feed liquor pipeline between detection cell and the first solenoid valve, and the second sensor is on the drain line between detection cell and the second solenoid valve.Further, first sensor is liquid level sensor, the second sensor also is liquid level sensor, owing at the feed liquor pipeline the first liquid level sensor being set, in drain line the second liquid level sensor is set, when the first liquid level sensor installation position is equipped with liquid and reaches, export a high level, the flow direction test chamber has been described, when the second liquid level sensor installation position is equipped with liquid and reaches, export a high level, illustrate that detecting intracavity liquid fills, at this moment the first solenoid valve and the second solenoid valve 5b are closed, liquid is closed in the pipeline, realize the purpose of sample introduction location, effectively avoided formation in urine in cell cavity, to drift about.Simultaneously, owing to by at feed tube and discharging tube difference equipped with non-contact liquid level sensor, having avoided the corrosion of urine Acidity of Aikalinity to the contact electrode material, cause short shortcoming in serviceable life.
The utility model also provides a kind of detection cell, comprises detection cell pond body, is arranged at least one test chamber on the body of detection cell pond, the transparent cover of pushing up in the chamber of test chamber, and described transparent cover or test chamber bottom are provided with telltale mark.Owing to being provided with telltale mark, focus as a reference by telltale mark, need not manually focus, but instrument focuses automatically, improved the analysis speed of instrument, the automaticity of instrument is improved greatly.Simultaneously, can accurately control sample on the microscope focal plane, make microscopes photograph clearly sample photo, make testing result more accurate.
In a kind of concrete embodiment, as shown in Figure 2, detection cell 1 comprises detection cell pond body 11, at detection cell pond body 11 three strip test chamber 12 are arranged, test chamber 12 is used for holding urine specimen, seal sample by in test chamber 12 transparent cover 13 being set, thereby avoid contaminated because of urine specimen, and cause analysis result inaccurate.In transparent cover 13 grid silk marks 130 is arranged, this grid silk marks 130 is as the reference marker of focusing, during microscope imaging, at first microscopical focal length is transferred to and is made grid silk marks imaging clearly, the judgement of this sharpness is judged automatically by software, when grid silk marks imaging clearly, at this moment microscopical focal plane is grid silk-screen focal plane.
Sample enters that test chamber 12 is rear usually will be through precipitation after a while, and great amount of samples can rest on a certain plane of sample in the test chamber, and this plane is exactly the sample focal plane.
The range difference of sample focal plane and grid silk-screen focal plane generally obtains by the empirical statistics data.By the grid silk marks microscope is focused, make microscopical focal plane be positioned at grid silk-screen focal plane, again according to the relation of sample focal plane and grid silk-screen focal plane, microscopical focal length is further regulated, make microscopical focal plane be positioned at the sample focal plane, thereby control realize microscopical automatic focusing function.
Please refer to such as Fig. 3, the relation of grid silk-screen focal plane and sample focal plane is as follows:
Z=Z0+ΔZ
Z: the sample focal plane is to the optocoupler distance that resets;
Z0: grid silk-screen focal plane is to the optocoupler distance that resets;
Δ Z: sample focal plane and grid silk-screen focal plane range difference.
Microscopical focusing moves to realize by driven by motor objective table and/or mobile object lens, and the starting point of motor movement judged by the optocoupler that resets, and the optocoupler that resets is positioned near the object lens of objective table top.
Telltale mark of the present utility model is in order to realize the focusing of microscope automatic focusing, be set in a reference marker on the transparent cover, microscope is at first by carrying out imaging to this reference marker, then according to the relation of reference marker and sample position, with microscopical focus adjustment to being positioned at the sample focal plane.
As long as being arranged on microscope, this telltale mark can become the position of image all can.Present embodiment is arranged on the transparent cover, and this telltale mark can be figure, such as grid, also can be pattern, can also be picture, can also be literal, such as the title of company, trade mark etc.The literal here is the literal of broad sense, comprises Chinese character, letter, symbol, perhaps also can be its combination.The demarcation mode can adopt the mode mark of silk-screen, also can adopt other mode mark.
This transparent cover can be cover glass, also can be plastic cover sheet, or other the cover plate with certain transparency material.This cover plate can with detection cell together moulding, also can be different assemblies separately, by glue detection cell pond body and cover plate are sticked together again.
In further concrete embodiment, cover glass comprises upper surface and lower surface, telltale mark can be arranged on upper surface, can be arranged on the centre of upper surface, also can be arranged on the edge of upper surface, also can be arranged on lower surface, same, can be arranged on the centre of lower surface, also can be arranged on the edge of lower surface.Preferably telltale mark is arranged on the lower surface of cover glass, avoids dropping on dust dirt on the telltale mark etc. and cause telltale mark unclear.Preferably be arranged on two ends on the transparent cover, avoid the tested sample zone, thereby imaging obtains the image planes of better tested sample.
Test chamber can be strip, also can be other shape, all can as long as can hold urine specimen, test chamber can be one, also can be a plurality of, such as two test chamber are set, when the sample to the first test chamber detects, can be simultaneously to the second test chamber feed liquor; When the pattern detection of the first test chamber complete, can be emptying to the first test chamber, simultaneously the sample of the second test chamber detected.Because a plurality of test chamber being set, different test chamber is carried out different job steps, has improved detection efficiency, has improved the analysis speed of Urine Analyzer.
This telltale mark can be one, also can be two, and perhaps a plurality of, specifically labelled number is more, and focusing usually can be more accurate.Such as two telltale marks are set, a telltale mark is for focusing, when a telltale mark is not known owing to reasons such as wear and aging, and another telltale mark can be used as for subsequent use; In addition, by two telltale marks are set, can proofread and correct a specifically labelled error, such as accommodating to a horizontal as much as possible focal plane, make the result of focusing more accurate, more be conducive to the accuracy of testing result.In a kind of concrete embodiment, by two grid silk marks are set, take continuously the N photo by microscope, by continuous adjustment, determine at last grid silk-screen focal plane, thereby obtain the more accurately position of grid silk-screen focal plane, thereby the position of the sample focal plane that obtains is also more accurate, the image of the sample that photographed is more clear, so that testing result is more accurate.
By telltale mark is set as the reference of focusing of microscope at cover glass, the position relationship by telltale mark and sample again, make focusing of microscope to the sample focal plane, instrument can be finished focusing automatically, improved the test speed of instrument, the degree of the robotization of Urine Analyzer is improved greatly.Simultaneously, microscopes photographs clearly sample photo, makes testing result more accurate.
The utility model also provides a kind of sample detection system, comprise above-mentioned detection cell, also comprise feed tube, discharging tube, be arranged on the first solenoid valve on the feed liquor pipeline, be arranged on the described feed tube of the second solenoid valve on the drain line, described detection cell, discharging tube connect successively, and described feed tube and described discharging tube are communicated with the test chamber of described detection cell respectively.
In a kind of concrete embodiment, as shown in Figure 4, this sample detection system comprise successively the feed tube 2 that connects, detection cell 1, discharging tube 3, the first sensor 4a that has or not for detection of liquid and the second sensor 4b, the first solenoid valve 5a, the second solenoid valve 5b.
The first solenoid valve 5a is arranged on the feed liquor pipeline, and the second solenoid valve 5b is arranged on the drain line, and first sensor 4a is arranged between detection cell 1 and the first solenoid valve 5a, and the second sensor 4b is arranged between detection cell 1 and the second solenoid valve 5b.
Detection cell also comprises detection cell pond body 11, at detection cell pond body three strip test chamber 12 is arranged, and test chamber 12 is used for holding urine specimen, as shown in Figure 5, feed tube 2 and discharging tube 3 respectively with test chamber 12 seamless links.Comprise that also 13 of glass covers that are arranged on the test chamber seal sample, thereby avoid contaminated because of urine specimen, and cause analysis result inaccurate.
Telltale mark arranges on the objective table, on the objective table table top such as objective table, can be arranged on the center section of objective table table top, also can be arranged on the edge of objective table table top; Can also be arranged on the detection cell, such as being arranged on the transparent cover, also can be arranged on the test chamber bottom; Can certainly be arranged on other assemblies, such as the detection cell fixation kit in fixed test pond, as long as microscopes is to this telltale mark imaging.
Microscopical concrete focusing process please refer to the embodiment of above-mentioned detection cell.
By telltale mark is set as the reference of focusing of microscope at cover glass, the position relationship by telltale mark and sample again, make focusing of microscope to the sample focal plane, instrument can be finished focusing automatically, improved the test speed of instrument, the degree of the robotization of Urine Analyzer is improved greatly.Simultaneously, microscopes photographs clearly sample photo, makes testing result more accurate.
Further, first sensor is liquid level sensor, the second sensor also is liquid level sensor, owing at the feed liquor pipeline the first liquid level sensor being set, in drain line the second liquid level sensor is set, when the first liquid level sensor installation position is equipped with liquid and reaches, export a high level, the flow direction test chamber has been described, when the second liquid level sensor installation position is equipped with liquid and reaches, export a high level, illustrate that detecting intracavity liquid fills, at this moment the first solenoid valve and the second solenoid valve 5b are closed, liquid is closed in the pipeline, realize the purpose of sample introduction location, effectively avoided formation in urine in cell cavity, to drift about.Simultaneously, owing to by at feed tube and discharging tube difference equipped with non-contact liquid level sensor, having avoided the corrosion of urine Acidity of Aikalinity to the contact electrode material, cause short shortcoming in serviceable life.
Further, one section that links to each other with detection cell 1 in the feed tube 2 is adopted silver pipe 201, and one section that links to each other with detection cell 1 in the discharging tube 3 is adopted silver pipe 301, effectively avoided the liquid sample corrosion.
Fixing for the ease of the installation of sensor and sensor, in the feed tube 2 away from another section of detection cell 1 with flexible pipe 202, this flexible pipe 202 and the pipe of be connected 201 connect, one section away from detection cell 1 in the discharging tube 3 is adopted flexible pipe 302, this flexible pipe 302 and be connected and manage 301 connections.
First sensor and the second sensor can be liquid level sensors, also can be capacitive transducers, also can be other the sensors that can tracer liquid has or not.
This first sensor also can dispense, and only uses the second sensor, when the second installation of sensors position has liquid to arrive, exports a high level, illustrates that detecting intracavity liquid fills.
Preferably include first sensor and the second sensor, the feed liquor of detection cell and fluid full symmetric can be exchanged like this, and be easier for installation; In addition, because first sensor being arranged, also be convenient to monitor discharge opeing, when first sensor detects no liquid, illustrate that year this detection intracavity liquid is emptying.
Above-mentioned each embodiment about detection cell, sample detection system and Urine Analyzer thereof is not limited to the declaratives to above-mentioned each theme, can support mutually.
Above content is in conjunction with concrete embodiment further description made for the present invention, can not assert that implementation of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, can also make some simple deduction or replace.
Claims (12)
1. Urine Analyzer, it is characterized in that, comprise microscope (6), be arranged on the objective table (601) on the microscope (6), the driven unit of control objective table (601) motion, can be by the telltale mark of microscope imaging, also comprise the feed tube (2) that connects successively, detection cell (1), discharging tube (3), be arranged on the first solenoid valve (4a) on the feed liquor pipeline, be arranged on the second solenoid valve (4b) on the drain line, described detection cell (1) is arranged on the objective table (601), and described feed tube (2) and described discharging tube (3) are communicated with described detection cell (1) respectively.
2. Urine Analyzer according to claim 1 is characterized in that, described telltale mark is arranged on objective table (601) or the described detection cell (1).
3. Urine Analyzer according to claim 2, it is characterized in that, described detection cell (1) comprises detection cell pond body (11), is arranged at least one test chamber (12) on the detection cell pond body (11), the transparent cover (13) of pushing up in the chamber of described test chamber (12), described feed tube (2) and discharging tube (3) are communicated with described test chamber (12) respectively, and described telltale mark is arranged on described detection cell and refers to that described telltale mark is arranged on transparent cover (13) upward or test chamber (12) bottom.
4. each described Urine Analyzer in 3 according to claim 1 is characterized in that, described telltale mark comprises at least two silk marks (130).
5. Urine Analyzer according to claim 4, it is characterized in that, also comprise the second sensor (5b) that has or not for detection of liquid, described the second sensor (5b) is positioned on the drain line between described detection cell (1) and described the second solenoid valve (4b).
6. Urine Analyzer detection cell, it is characterized in that, comprise detection cell pond body (11), be arranged at least one test chamber (12) on the detection cell pond body (11), the transparent cover (13) of pushing up in the chamber of described test chamber (12), described transparent cover (13) or described test chamber (12) bottom are provided with telltale mark.
7. detection cell according to claim 6 is characterized in that, described transparent cover (13) is cover glass, and described cover glass (13) comprises cover plate upper surface and cover plate lower surface, and described telltale mark is arranged on described cover glass lower surface.
8. detection cell according to claim 6 is characterized in that, described telltale mark is arranged on the position of avoiding surveyed area on the transparent cover (13).
9. according to claim 7 or 8 described detection cells, it is characterized in that, described telltale mark comprises at least two silk marks (130).
10. Urine Analyzer sample detection system, it is characterized in that, comprise such as each described detection cell (1) in the claim 6 to 8, also comprise feed tube (2), discharging tube (3), be arranged on the first solenoid valve (4a) on the feed liquor pipeline, be arranged on the described feed tube of the second solenoid valve (4b) (2) on the drain line, described detection cell (1), discharging tube (3) connects successively, and described feed tube (2) and described discharging tube (3) are communicated with the test chamber (12) of described detection cell (1) respectively.
11. sample detection according to claim 10 system, it is characterized in that, also comprise the second sensor (5b) that has or not for detection of liquid, described the second sensor (5b) is positioned on the drain line between described detection cell (1) and described the second solenoid valve (4b).
12. sample detection according to claim 11 system, it is characterized in that, also comprise the first sensor (5a) that has or not for detection of liquid, described first sensor is positioned on the feed liquor pipeline of described detection cell (1) and described the first solenoid valve (4a), one section of linking to each other with test chamber (12) of described feed tube (2) is feed liquor silver pipe (201), described feed tube (2) is feed liquor flexible pipe (202) away from another section of detection cell, one section of linking to each other with detection cell (1) of described discharging tube (3) is discharge opeing silver pipe (301), described discharging tube (3) is discharge opeing flexible pipe (302) away from the other end of detection cell, described first sensor (5a) and the first solenoid valve (4a) are positioned on the feed liquor flexible pipe (202), and described the second sensor (5b) and the second solenoid valve (4b) are positioned on the discharge opeing flexible pipe (302).
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CN 201220536142 CN203249859U (en) | 2012-10-18 | 2012-10-18 | Detection pool, sample introduction detecting system and urine analysis instrument |
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CN 201220536142 CN203249859U (en) | 2012-10-18 | 2012-10-18 | Detection pool, sample introduction detecting system and urine analysis instrument |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2014059858A1 (en) * | 2012-10-18 | 2014-04-24 | 苏州惠生电子科技有限公司 | Microscope image detecting instrument and automatic focusing method therefor |
CN105067783A (en) * | 2015-07-17 | 2015-11-18 | 成都汉康信息产业有限公司 | Edible oil quality detection equipment |
CN109884065A (en) * | 2018-09-05 | 2019-06-14 | 中国航发动力股份有限公司 | A method of element groove is detected using plane mirror |
CN115248213A (en) * | 2021-04-27 | 2022-10-28 | 深圳市瑞图生物技术有限公司 | Microscopic examination card and microscopic examination method |
-
2012
- 2012-10-18 CN CN 201220536142 patent/CN203249859U/en not_active Expired - Lifetime
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014059858A1 (en) * | 2012-10-18 | 2014-04-24 | 苏州惠生电子科技有限公司 | Microscope image detecting instrument and automatic focusing method therefor |
US9703171B2 (en) | 2012-10-18 | 2017-07-11 | Suzhou Hyssen Electronics Co., Ltd | Microscopic image detecting instrument and automatic focusing method therefor |
CN105067783A (en) * | 2015-07-17 | 2015-11-18 | 成都汉康信息产业有限公司 | Edible oil quality detection equipment |
CN109884065A (en) * | 2018-09-05 | 2019-06-14 | 中国航发动力股份有限公司 | A method of element groove is detected using plane mirror |
CN115248213A (en) * | 2021-04-27 | 2022-10-28 | 深圳市瑞图生物技术有限公司 | Microscopic examination card and microscopic examination method |
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Address after: Unit 501, Building 218, Sangtian Street, Suzhou Industrial Park, Jiangsu Province Patentee after: SUZHOU MAIRUI TECHNOLOGY Co.,Ltd. Address before: Unit 213-216, A3 Building, 218 Xinghu Street, Suzhou Industrial Park, Jiangsu Province Patentee before: Suzhou Hyssen Electronics Co.,Ltd. |
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