CN203235152U - Intracavity frequency-doubling all-solid-state raman yellow orange laser skin vascular disease therapeutic instrument - Google Patents
Intracavity frequency-doubling all-solid-state raman yellow orange laser skin vascular disease therapeutic instrument Download PDFInfo
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- CN203235152U CN203235152U CN 201220625306 CN201220625306U CN203235152U CN 203235152 U CN203235152 U CN 203235152U CN 201220625306 CN201220625306 CN 201220625306 CN 201220625306 U CN201220625306 U CN 201220625306U CN 203235152 U CN203235152 U CN 203235152U
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Abstract
The utility model discloses an intracavity frequency-doubling all-solid-state raman yellow orange laser skin vascular disease therapeutic instrument, which comprises a semiconductor laser pumped system, an intracavity frequency-doubling raman yellow orange laser resonator, a fiber coupling mirror, a transmission fiber and a treatment handle. The semiconductor laser pumped system is composed of a pump light source and an optical coupling part. The intracavity frequency-doubling raman yellow orange laser resonator is composed of an input endoscope, a laser gain medium, a raman frequency shift medium, a frequency-doubling laser reflector, a frequency-doubling crystal and an output endoscope which are sequentially arranged. During a treatment process, yellow orange laser rays which are transmitted through the transmission fiber and transformed with light spots of the treatment handle are then irradiated to the inner sides of blood vessels under the skin epidermis of a patient. The laser rays are further absorbed by ferrohemoglobin. By means of the selective light pyrolysis principle, the yellow orange laser rays act on the ferrohemoglobin inside the diseased blood vessels and make the diseased blood vessels undergo pyrolysis and further absorbed and finally disappear. The aim of treating blood vessel diseases is thus achieved. The treatment effects are apparent.
Description
Technical field
This utility model relates to semiconductor laser pumping total solids laser technology, the excited Raman laser technology, and intracavity frequency doubling technology and laser medical beauty treatment technology are specifically related to a kind of intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument.
Background technology
Cutaneous vacular lesion comprises vascular malformation and hemangioma two large classes, common are nevus flammeus, strawberry hemangioma, telangiectasis, rosacea, varicose veins of the lower extremity etc., can betide each position of whole body body surface, except causing the cosmetic defect to the patient, can also cause the corresponding function obstacle.Traditional Therapeutic Method has Drug therapy, liquid nitrogen cryotherapy, injection sclerosants, blood vessel ligation treatment and surgical operation etc., these non-selectivities have wound treatment larger to normal skin tissue's damage, the complication of often following the patients such as cicatrix, pigment alteration to be difficult to accept.
Along with the application of laser technology at medical domain, for the treatment of cutaneous vacular lesion provides effective means.The laser of specific wavelength is by selective light pyrolysis principle, act on the hemoglobin in the lesion vessels, make lesion vessels pyrolysis, absorption, disappearance, reach the treatment vascular lesion and not around damaged tissue and the skin and without the purpose of cicatrization, be to treat at present the method that vascular lesions the most effectively has no side effect.
Along with the development of semiconductor laser technique, all solid laser of this laser pump (ing) also begins to be applied to the treatment of cutaneous vacular lesion.Be in the 532nm total solids laser energy of green light band by the hemoglobin good absorption such as wavelength, continuous laser treatment time width setting can approach with patient's thermal relaxation time, these characteristics are so that this laser becomes the first-selected therapeutic equipment for the treatment of vascular lesions.
Experimental data shows, although the absorptance of the HbO2 Oxyhemoglobin of 532nm is higher, but melanic absorption is also higher, and the laser of this wavelength is only applicable to the treatment of the thinner blood vessel of skin superficial face, and the treatment of the less white race's of dermal melanin skin surface vascular conditions.In order to increase the treatment degree of depth of veins beneath the skin, usually adopt the semiconductor laser of the infrared band of long 808nm, 940nm, 980nm and 1064nm of wavelength, but the absorptance of the hemoglobin of this wave band is lower, for thinner blood vessel, the wide part of this wave band sees through, and is absorbed by skin on every side.
Near the wavelength 577nm yellow orange is another absworption peak of oxygen and hemoglobin only, and along with the increase of wavelength, melanic absorption reduces, has close hemoglobin absorptance such as the yellow orange light of 585nm and the green glow of 532nm, but melanic absorption only is 532nm half, so yellow orange light is more suitable in non-white race and is positioned under the skin the darker treatment of vascular conditions.The cutaneous vacular lesion therapeutic instrument of yellow orange laser mainly adopts the pulsed dye laser of flash lamp pumping 585nm and 595nm at present.But dye laser has poor stability, dye degradation and toxic, the series of problems such as energy expenditure is high, poor stability, and is so that the design of dye laser is very complicated, bulky.Because the peak power of pulse laser is very high, adopt this laser therapy vascular disease of the skin to be easy to cause the side effect such as purpura simultaneously.
The utility model content
For addressing the above problem, this utility model provides a kind of intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument, have that volume is little, lightweight, compact conformation, power consumptive province and the characteristics such as be easy to carry, the output wave band of laser arrives 600nm at 550nm, the relaxation time of output time and skin by the modulation continuous laser is close, can obtain the therapeutic effect of the vascular disease of the skin of preferably selectivity absorption.
For realizing above-mentioned technical purpose, reach above-mentioned technique effect, this utility model is achieved through the following technical solutions:
A kind of intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument comprises semiconductor laser pumping system, intracavity frequency doubling Raman yellow orange laserresonator, fibre-coupled mirrors, Transmission Fibers and treatment hands handle; Described semiconductor laser pumping system is comprised of pump light source and optical coupling part, and it is arranged sequentially that described intracavity frequency doubling Raman yellow orange laserresonator is pressed input cavity mirror, gain medium, Raman frequency shift medium, double-frequency laser reflecting mirror, frequency-doubling crystal and output cavity mirror; Described treatment handle contact human body surface.
Further, described pump light source be the wavelength of continuous or quasi-continuous output be 790nm to semiconductor laser, semiconductor laser array or the semiconductor laser stacks of 980nm, carry out temperature control by semiconductor cooler, circulating fluid and circulated air; Described optical coupling part is a kind of or its combination wherein of coquille, aspherical mirror, cylindrical mirror, GRIN Lens, optical fiber, prism, micro lens array, binary optical lenses, and prepares the anti-reflection film of pump light at its logical bright finish.
Further, described gain medium is Nd:YAG, Nd:YVO
4, Nd:GdVO
4, or other mixes Nd
3+, Yb
3+Or Pr
3+The laser crystal of ion or laser ceramic material; Described Raman frequency shift medium is YVO
4, GdVO
4, or the crystalline material that has the excited Raman effect such as tungstates and nitrate etc.; Described frequency-doubling crystal is LBO, KTP, and KTA, BiBO, the nonlinear optical crystals such as PPMgLN or BBO adopt critical, non-critical phase matched or periodic polarized accurate position to be complementary.
Further, described gain medium and described Raman frequency shift medium adopt at Nd:YVO
4One or both ends, or Nd:GdVO
4One or both ends by ion diffusion bond and technology respectively key and YVO
4Or GdVO
4, become an ionic bond and crystal.
Further, described gain medium and described Raman frequency shift medium adopt a Nd:YVO
4, Nd:GdVO
4Or other mixes Nd
3+, Yb
3+Or Pr
3+The gain medium with self-stimulated Raman effect of ion replaces described gain medium and described Raman frequency shift medium, and a crystal is finished laser transition and two kinds of functions of Raman frequency shift simultaneously.
Further, described fibre-coupled mirrors be focal length greater than the positive focal length lens of 10mm, two logical bright finish of lens prepare the anti-reflection film of yellow orange laser.
Further, described Transmission Fibers core diameter is 200 microns to 1000 microns multimode fibre.
Further, adopt two or more than two battery of lens in the described treatment handle, the focus of first lens or battery of lens is positioned near the Transmission Fibers outlet, by regulating axial distance, make output beam pass through to be collimated light beam behind first lens or the battery of lens collimation, according to the focal length of second lens of size Selection for the treatment of hot spot or change the focal length of lens by changing distance between the lens in the battery of lens, obtain the different treatment spot sizes that are radiated on the patient's skin surface; The treatment spot size that is radiated on the patient's skin surface by described treatment handle is that 0.3mm is between the 10mm; Modulated pumping light source works electric current makes to be output as pulsed operation, and its pulse working time is that 0.5ms is to 10s.
The beneficial effects of the utility model are:
This utility model is after the hot spot conversion of when treatment yellow orange laser by beam Propagation and treatment handle, shine in the subepidermal blood vessel of patient skin, absorbed by hemoglobin, by selective light pyrolysis principle, the hemoglobin of yellow orange laser action in lesion vessels, make lesion vessels pyrolysis, absorption, disappearance, reach the purpose for the treatment of vascular lesion, therapeutic effect is remarkable.
Description of drawings
Fig. 1 is internal structure sketch map of the present utility model.
The number in the figure explanation:
1, pump light source, 2, optical coupling part, 3, the input cavity mirror, 4, gain medium, 5, Raman frequency shift medium, 6, the double-frequency laser reflecting mirror, 7, frequency-doubling crystal, 8, the output cavity mirror, 9, fibre-coupled mirrors, 10, Transmission Fibers, 11, the treatment handle, 12, human body surface.
The specific embodiment
Referring to shown in Figure 1, a kind of intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument comprises semiconductor laser pumping system, intracavity frequency doubling Raman yellow orange laserresonator, fibre-coupled mirrors 9, Transmission Fibers 10 and treatment handle 11; Described semiconductor laser pumping system is comprised of pump light source 1 and optical coupling part 2, described intracavity frequency doubling Raman yellow orange laserresonator by input cavity mirror 3, gain medium 4, Raman frequency shift medium 5, doubly to contact frequency laser reflecting mirror 6, frequency-doubling crystal 7 and output cavity mirror 8 arranged sequentially; Described treatment handle 11 contact human body surfaces 12.
Further, described pump light source 1 for wavelength continuous or quasi-continuous output be 790nm to semiconductor laser, semiconductor laser array or the semiconductor laser stacks of 980nm, carry out temperature control by semiconductor cooler, circulating fluid and circulated air; Described optical coupling part 2 is a kind of or its combination wherein of coquille, aspherical mirror, cylindrical mirror, GRIN Lens, optical fiber, prism, micro lens array, binary optical lenses, and prepares the anti-reflection film of pump light at its logical bright finish.
Further, described gain medium 4 is Nd:YAG, Nd:YVO
4, Nd:GdVO
4, or other mixes Nd
3+, Yb
3+Or Pr
3+The laser crystal of ion or laser ceramic material; Described Raman frequency shift medium 5 is YVO
4, GdVO
4, or the crystalline material that has the excited Raman effect such as tungstates and nitrate etc.; Described frequency-doubling crystal 7 is LBO, KTP, and KTA, BiBO, the nonlinear optical crystals such as PPMgLN or BBO adopt critical, non-critical phase matched or periodic polarized accurate position to be complementary.
Further, described gain medium 4 and described Raman frequency shift medium 5 adopt at Nd:YVO
4One or both ends, or Nd:GdVO
4One or both ends by ion diffusion bond and technology respectively key and YVO
4Or GdVO
4, become an ionic bond and crystal.
Further, described gain medium 4 and described Raman frequency shift medium 5 adopt a Nd:YVO
4, Nd:GdVO
4Or other mixes Nd
3+, Yb
3+Or Pr
3+The gain medium with self-stimulated Raman effect of ion replaces described gain medium 4 and 5, crystal of described Raman frequency shift medium to finish simultaneously laser transition and two kinds of functions of Raman frequency shift.
Further, described fibre-coupled mirrors 9 be focal length greater than the positive focal length lens of 10mm, two logical bright finish of lens prepare the anti-reflection film of yellow orange laser.
Further, described Transmission Fibers 10 core diameters are 200 microns to 1000 microns multimode fibre.
Further, described treatment handle 11 two of interior employings or more than two battery of lens, the focus of first lens or battery of lens is positioned near the Transmission Fibers outlet, by regulating axial distance, make output beam pass through to be collimated light beam behind first lens or the battery of lens collimation, according to the focal length of second lens of size Selection for the treatment of hot spot or change the focal length of lens by changing distance between the lens in the battery of lens, obtain the different treatment spot sizes that are radiated on the patient's skin surface; The treatment spot size that is radiated on the patient's skin surface by described treatment handle 11 is that 0.3mm is between the 10mm; Modulated pumping light source works electric current makes to be output as pulsed operation, and its pulse working time is that 0.5ms is to 10s.
It is the 880nm semiconductor laser array that described pump light source 1 adopts the wavelength of optical fiber output, and the optical fiber core diameter is 200 microns, and numerical aperture is 0.22; Described optical coupling part 2 is comprised of two planoconvex lens, the anti-reflection film of preparation 880nm wavelength, the plane of first planoconvex lens is towards optical fiber, the plane of second planoconvex lens towards opposite with the first planoconvex lens; Described input cavity mirror 3 is average lens, and the preparation of its pump light plane of incidence is to the anti-reflection film of 880nm, and the another side preparation is anti-reflection to the pump light of 880nm, the high anti-multilayer dielectric film of Raman light of the fundamental frequency light of 1063nm and 1173nm; Described gain medium 4 is Nd:GdVO
4Laser crystal adopts the transition spectral line of its 1063nm, and the two ends of described gain medium 4 prepare the fundamental frequency light of 1063nm and the Raman spectra permeable membrane of 1173nm; Also can remove independent described input cavity mirror 3, multilayer dielectric film is directly prepared input face at described gain medium 4, at this moment the pump light input face of described gain medium 4 will prepare the fundamental frequency light of, 1063nm anti-reflection to the pump light of 880nm and the high anti-multilayer dielectric film of Raman light of 1173nm, and another side prepares the fundamental frequency light of 1063nm and the Raman spectra permeable membrane of 1173nm; Described Raman frequency shift medium 5 is GdVO
4Crystal, the two ends of described Raman frequency shift medium 5 prepare the anti-reflection film of 1063nm fundamental frequency light and 1173nm Raman light; GdVO as the Raman frequency shift medium
4Also can with corresponding gain medium Nd:GdVO
4By ionic bond with form a crystal, and key and connecting surface need not prepare the anti-reflection film of the Raman light of the fundamental frequency light of 1063nm and 1173nm; Or only adopt a gain medium Nd:GdVO
4, Nd:GdVO
4Namely as gain medium, also conduct is from the Raman frequency shift medium, and a crystal is realized laser transition and two kinds of functions of Raman frequency shift simultaneously; Described double-frequency laser reflecting mirror 6 is plane mirrors, and one surface prepares the anti-reflection film of 1063nm and 1173nm, and another side prepares 1063nm and 1173nm is anti-reflection and the high anti-multilayer dielectric film of 586.5nm; Described frequency-doubling crystal 7 adopts non-critical phase matched LBO nonlinear optical crystal, and crystal is carried out temperature control, the control temperature is about 45 degree, realize the phase difference Δ k=0 of Raman light and frequency doubled light, two logical bright finish of this crystal prepare 1063nm and 1173nm is anti-reflection and the anti-reflection film of 586.5nm; Described output cavity mirror 8 adopts the plano-concave mirrors, and the concave curvature radius is 200mm, and concave surface prepares that the yellow orange light of 586.5nm is anti-reflection, the fundamental frequency light of 1063nm and the high anti-multilayer dielectric film of Raman light of 1173nm, and the plane prepares 586.5nm yellow orange light anti-reflection film.Described fibre-coupled mirrors 9 is the condenser lens of focal length 40mm, regulates lens position, satisfies numerical aperture NA less than 0.22 when making 586.5nm yellow orange light focus in the optical fiber, and spot diameter is less than 400 microns requirement; Described Transmission Fibers 10 adopts sonet standard joint and the core diameter=400um of SMA905, the silica fibre of NA=0.22; Two lens of described treatment handle 11 interior employings, the focus of first lens is positioned near the optical fiber outlet, by regulating axial location, make output beam pass through to be collimated light beam after the first collimated, focal length according to second lens of size Selection for the treatment of hot spot, when the focal length of second lens is 5 times of first lens focal length, the spot size that incides the treatment skin surface is 2mm, if inciding the laser power of human body surface 12 is 5W, when the pulse width of laser works was 50ms, the irradiation energy of the human body surface 12 that is treated was 8J/cm
2, should be able to reach the needed energy of skin heart sexually transmitted disease (STD), can be used for the treatment of the vascular disease of the skin such as telangiectasis, reach certain therapeutic effect.
During this therapeutic instrument work, described pump light source 1 is sent the pump light of 880nm, two planoconvex lens compositions by described optical coupling part 2 are coupled in the Nd:GdVO4 of described gain medium 4, produce the fundamental frequency light of 1063nm, fundamental frequency light vibrates in the basic frequency laser resonator cavity of described input cavity mirror 3 and described output cavity mirror 8 compositions.When fundamental frequency light passes through described Raman frequency shift medium 5 GdVO4, produce the 1173nm raman laser by the conversion of intracavity Raman, and in the raman laser resonator cavity of described input cavity mirror 3 and described output cavity mirror 8 compositions, vibrate.When raman laser passes through described frequency-doubling crystal 7LBO, producing wavelength is the yellow orange laser of 586.5nm, propagate 586.5nm yellow orange laser to described output cavity mirror 8 directions and directly export, the 586.5nm yellow orange laser of propagating with described output cavity mirror 8 rightabouts by described double-frequency laser reflecting mirror 6 reflections after also by described output cavity mirror 8 outputs; After 586.5nm yellow orange laser is exported by described output cavity mirror 8, be coupled in the described Transmission Fibers 10 by described fibre-coupled mirrors 9, by the described treatment handle 11 that forms by having two lens after the optical fiber output, be transformed to the hot spot of 2mm diameter, shine in the blood vessel under the patients' such as telangiectasis that are treated the skin.According to selective light pyrolysis principle, the yellow orange laser irradiation is in lesion vessels, act on the hemoglobin in the lesion vessels, make lesion vessels pyrolysis, absorption, disappearance, reach treatment telangiectasis people vascular lesion and not around damaged tissue and the skin and without the purpose of cicatrization.
More than a kind of intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument and system that this utility model embodiment is provided be described in detail, the explanation of above embodiment just is used for helping to understand method of the present utility model and thought thereof; Simultaneously, for one of ordinary skill in the art, according to thought of the present utility model, will change in specific embodiments and applications, in sum, this description should not understood restriction of the present utility model.
Claims (5)
1. an intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument is characterized in that: comprise semiconductor laser pumping system, intracavity frequency doubling Raman yellow orange laserresonator, fibre-coupled mirrors (9), Transmission Fibers (10) and treatment handle (11); Described semiconductor laser pumping system is comprised of pump light source (1) and optical coupling part (2), and it is arranged sequentially that described intracavity frequency doubling Raman yellow orange laserresonator is pressed input cavity mirror (3), gain medium (4), Raman frequency shift medium (5), double-frequency laser reflecting mirror (6), frequency-doubling crystal (7) and output cavity mirror (8); Described treatment handle (11) contact human body surface (12).
2. intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument according to claim 1, it is characterized in that: described pump light source (1) for wavelength continuous or quasi-continuous output be 790nm to semiconductor laser, semiconductor laser array or the semiconductor laser stacks of 980nm, carry out temperature control by semiconductor cooler, circulating fluid and circulated air; Described optical coupling part (2) is a kind of or its combination wherein of coquille, aspherical mirror, cylindrical mirror, GRIN Lens, optical fiber, prism, micro lens array, binary optical lenses, and prepares the anti-reflection film of pump light at its logical bright finish.
3. intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument according to claim 1, it is characterized in that: described Transmission Fibers (10) core diameter is 200 microns to 1000 microns multimode fibre.
4. intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument according to claim 1, it is characterized in that: adopt two or more than two battery of lens in the described treatment handle (11), the focus of first lens or battery of lens is positioned near the Transmission Fibers outlet, by regulating axial distance, make output beam pass through to be collimated light beam behind first lens or the battery of lens collimation, according to the focal length of second lens of size Selection for the treatment of hot spot or change the focal length of lens by changing distance between the lens in the battery of lens, obtain the different treatment spot sizes that are radiated on the patient's skin surface; The treatment spot size that is radiated on the patient's skin surface by described treatment handle (11) is that 0.3mm is between the 10mm.
5. intracavity frequency doubling total solids Raman yellow orange laser skin vascular lesions therapeutic instrument according to claim 1 is characterized in that: modulated pumping light source (1) operating current, and making the yellow orange Laser output is pulsed operation, its pulse working time is that 0.5ms is to 10s.
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|---|---|---|---|
| CN 201220625306 CN203235152U (en) | 2012-11-23 | 2012-11-23 | Intracavity frequency-doubling all-solid-state raman yellow orange laser skin vascular disease therapeutic instrument |
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| CN 201220625306 CN203235152U (en) | 2012-11-23 | 2012-11-23 | Intracavity frequency-doubling all-solid-state raman yellow orange laser skin vascular disease therapeutic instrument |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103830846A (en) * | 2012-11-23 | 2014-06-04 | 苏州生物医学工程技术研究所 | Intracavity frequency-multiplication all-solid Raman yellow-orange-laser skin vascular lesion therapeutic instrument |
| CN103877679A (en) * | 2014-04-18 | 2014-06-25 | 深圳天基权健康科技集团股份有限公司 | Semiconductor laser synthesizer therapeutic instrument |
| CN104568897A (en) * | 2013-10-29 | 2015-04-29 | 苏州拉曼检测技术有限公司 | Raman spectrum enhancement device, raman spectrum enhancement system and raman spectrum enhancement method based on external resonant cavity technology |
-
2012
- 2012-11-23 CN CN 201220625306 patent/CN203235152U/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103830846A (en) * | 2012-11-23 | 2014-06-04 | 苏州生物医学工程技术研究所 | Intracavity frequency-multiplication all-solid Raman yellow-orange-laser skin vascular lesion therapeutic instrument |
| CN104568897A (en) * | 2013-10-29 | 2015-04-29 | 苏州拉曼检测技术有限公司 | Raman spectrum enhancement device, raman spectrum enhancement system and raman spectrum enhancement method based on external resonant cavity technology |
| CN104568897B (en) * | 2013-10-29 | 2017-12-12 | 中国计量大学 | Raman spectrum intensifier, system and method based on chamber exterior resonant cavity technology |
| CN103877679A (en) * | 2014-04-18 | 2014-06-25 | 深圳天基权健康科技集团股份有限公司 | Semiconductor laser synthesizer therapeutic instrument |
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