CN203220691U - Laser photodynamic therapeutic instrument - Google Patents

Laser photodynamic therapeutic instrument Download PDF

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Publication number
CN203220691U
CN203220691U CN 201320232221 CN201320232221U CN203220691U CN 203220691 U CN203220691 U CN 203220691U CN 201320232221 CN201320232221 CN 201320232221 CN 201320232221 U CN201320232221 U CN 201320232221U CN 203220691 U CN203220691 U CN 203220691U
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China
Prior art keywords
optical fiber
light
therapeutic instrument
laser
photodynamic
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CN 201320232221
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Chinese (zh)
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刘伟
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Sichuan Peoples Hospital of Sichuan Academy of Medical Sciences
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Sichuan Peoples Hospital of Sichuan Academy of Medical Sciences
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Abstract

The utility model relates to the field of medical instruments, and specifically relates to a laser photodynamic therapeutic instrument. The laser photodynamic therapeutic instrument comprises a laser emission device capable of generating light having a wavelength of 200-1500 nm, and an optical fiber, wherein one end of the optical fiber is connected with the laser emission device, while the other end is a therapeutic terminal which can be guided into human tissues. According to the utility model, light energy is guided to a target tissue through the optical fiber to carry out partial irradiation, so that side-effects of damage to normal tissues around in the disease treatment using photodynamic outside-tissue irradiation in the prior art is prevented, and the curative effect is improved by shortening the irradiation distance; light, such as blue light, which has a wavelength of less than 600 nm and is weak in penetration, is guided to the target tissue by the optical fiber, barrier dielectric between the light and the target tissue is reduced, and the operating distance of the light is shorted, so that the problem that light being weak in penetration cannot be used in photodynamic therapy is solved, and the application range of the photodynamic therapy is broadened; besides, the use of disposable photodynamic optical fiber can meet the medical and health standards, thereby reducing the use cost for patients.

Description

A kind of laser power therapeutic instrument
Technical field
This utility model relates to medical instruments field, particularly a kind of laser power therapeutic instrument of optical dynamic therapy.
Background technology
The effect basis of photodynamic therapy (Photodynamic Therapy, abbreviation PDT) is photodynamic effect, and this is a kind of photosensitization reaction of following biological effect that has oxygen molecule to participate in.Its process is the rayed by specific wavelength (scope), the photosensitizer that tissue is absorbed is excited, and the photosensitizer of excited state is the energy delivery oxygen supply, generate active very strong singlet oxygen, singlet oxygen again with adjacent biomacromolecule generation oxidation reaction, produce cell toxicant, and then cause cell impaired and even dead.PDT generally carries out in two steps, at first is to use photosensitizer to the patient, is that focal zone is carried out rayed then.
Photodynamic therapy (PDT) is international, domestic new a kind of effective methods for the treatment of diseases of carrying out use in recent years, it all is widely used in department of dermatologry, urology department, ophthalmology, oncology, department of obstetrics and gynecology, the department of stomatology, neurosurgery etc., such as photodynamic therapy the common acne of department of dermatologry is had tangible curative effect.Openly be used for the treatment of the employed photodynamic therapeutic instrument of dermopathic photodynamic therapy (PDT) in the prior art and mainly pass through the red-light LED scattered light as light source, large tracts of land is carried out at the position that scribbles photosensitizer organize external exposure, because what adopt is that the LED scattered light is organized external exposure, in the irradiation process to the patient, untoward reaction be may occur, burn feeling, scratchiness or sensation of pricking partly had such as normal skin; Treatment finishes the back light position and erythema, edema, pain, part patient often occur even comparatively serious reactive acne, Secondary cases pigmentation and exfoliation may occur.In addition according to experimental results show that, blue light has stronger inhibitory action by the light principle of dynamics to the important step " propionibacterium acnes " in the acne morbidity than HONGGUANG, but because blue light wavelength is below 600nm, its to the penetration power of skin a little less than, can not reach the target function of organization degree of depth, cause the effect of blue light on the acne optical dynamic therapy not to be developed.
The utility model content
The purpose of this utility model is to overcome the above-mentioned deficiency of prior art, provide a kind of can be accurately at the laser power therapeutic instrument of interstitial irradiation's target site.
For achieving the above object, this utility model provides following technical scheme:
A kind of laser power therapeutic instrument comprises laser beam emitting device and the optical fiber that can produce the 200-1500nm wavelength light, and an end of described optical fiber is connected with laser beam emitting device, and the other end is for importing the treatment termination in the tissue.
In the above-mentioned laser power therapeutic instrument, described treatment termination is an end of optical fiber, and this end can directly insert and carry out rayed in the tissue.
In the above-mentioned laser power therapeutic instrument, described laser power therapeutic instrument also comprises one-time treatment optical fiber and adapter, and described one-time treatment optical fiber is connected with an end of optical fiber by adapter, and the other end of optical fiber connects laser beam emitting device.
In the above-mentioned laser power therapeutic instrument, the light that described laser beam emitting device sends is HONGGUANG or near infrared light, and the optical source wavelength of described HONGGUANG or near infrared light is 600-900nm, the output power density 1-150mW/cm of described HONGGUANG or near infrared light 2
In the above-mentioned laser power therapeutic instrument, the light that described laser beam emitting device sends is blue light, and described blue light source wavelength is 400-490nm, described blue light output power density 1-150mW/cm 2
In the above-mentioned laser power therapeutic instrument, the core diameter of described optical fiber and one-time treatment optical fiber is 1-5000 μ m.
In the above-mentioned laser power therapeutic instrument, the laser of the specific wavelength that laser beam emitting device produces need not penetrate outer the stopping of target tissue and organize medium, arrive the target location by optical fiber, laser light energy is directly acted on the target tissue realize internal radiation, increase light power curative effect, reduced the side effect of light power external exposure.
Compared with prior art, the beneficial effects of the utility model: this utility model imports to the target tissue by optical fiber with luminous energy and carries out local internal radiation, the impaired side effect of normal surrounding tissue in the time of can effectively avoiding present light motor tissue external radiotherapy disease is simultaneously by shortening the effect that irradiation distance reaches increases curative effect.In addition, introduce target tissue by the location of the light (such as blue light) below the optical fiber wavelength 600nm that penetration power is more weak, reduced the obstruct medium between itself and the target tissue, shortened its operating distance, thereby solve the problem that it can not be applied to optical dynamic therapy a little less than because of penetration power, though give full play to a little less than the following light penetration power of wavelength 600nm, the special role advantage is arranged, widened the usage range of optical dynamic therapy.The use of one-time treatment optical fiber meets the health care standard, effectively reduces patient's use cost.
Description of drawings
Fig. 1 is the structural representation of embodiment 1.
Fig. 2 is the structural representation of embodiment 2.
Fig. 3 is the fractionation structural representation of Fig. 2.
Labelling among the figure: 1-laser beam emitting device, 2-optical fiber, 3-one-time treatment optical fiber, 4-adapter, 5-termination.
The specific embodiment
Below in conjunction with the drawings and specific embodiments this utility model is further described.
In order to make the purpose of this utility model, technical scheme and advantage clearer, below in conjunction with drawings and Examples, this utility model is further elaborated.Should be appreciated that specific embodiment described herein only in order to explaining this utility model, and be not used in restriction this utility model.
Embodiment 1
As shown in Figure 1, the laser power therapeutic instrument of present embodiment, comprise the optical fiber 2 that the laser beam emitting device 1 that can produce HONGGUANG or blue light and core diameter are 200 μ m, one end of described optical fiber 2 is connected with laser beam emitting device 1, the other end is for importing the termination 5 in the tissue, this termination 5 is an end of optical fiber 2, this end can directly insert and carry out rayed in the tissue, this optical fiber 2 can be common optical fiber, but patients uses jointly after sterilization, also can be disposable optical fiber, carry out disposable use.
When carrying out optical dynamic therapy at dermatosiss such as acnes, the laser power therapeutic instrument that cooperates present embodiment after the local external application of employing photosensitizer again, the HONGGUANG of coming out from laser beam emitting device 1 or the blue light termination 5 by optical fiber 2 imports to skin lesion target tissue and carries out interstitial irradiation, can reach accurate target position treatment, avoid the normal structure damaged, simultaneously by shortening the effect that irradiation distance reaches increases curative effect.
Embodiment 2
Shown in accompanying drawing 2,3, the laser power therapeutic instrument of present embodiment is with embodiment 1, difference is that present embodiment also comprises one-time treatment optical fiber 3 and adapter 4, one end of described one-time treatment optical fiber 3 is connected with optical fiber 2 by adapter 4, the other end inserts target tissue, and laser light energy is acted on target tissue.In use, the HONGGUANG or the blue light that come out from laser beam emitting device 1 carry out internal radiation through optical fiber 2, adapter 4, one-time treatment optical fiber 3 importing skin lesion target tissues successively, because the optical fiber 3 of property treatment for once contacts with patient's tissue, only need the lower one-time treatment optical fiber of replacement cost at different patients, clean hygiene, meet medical standard, reduce patient's use cost.
The above only is preferred embodiment of the present utility model; not in order to limit this utility model; all any modifications of within spirit of the present utility model and principle, doing, be equal to and replace and improvement etc., all should be included within the protection domain of the present utility model.

Claims (5)

1. laser power therapeutic instrument, it is characterized in that: comprise laser beam emitting device and the optical fiber that can produce the 200-1500nm wavelength light, an end of described optical fiber is connected with laser beam emitting device, and the other end is for importing the treatment termination in the tissue.
2. laser power therapeutic instrument according to claim 1, it is characterized in that: described laser power therapeutic instrument also comprises one-time treatment optical fiber and adapter, described one-time treatment optical fiber is connected with an end of optical fiber by adapter, and the other end of optical fiber connects laser beam emitting device.
3. laser power therapeutic instrument according to claim 1, it is characterized in that: the light that described laser beam emitting device sends is HONGGUANG or near infrared light, the optical source wavelength of described HONGGUANG or near infrared light is 600-900nm, the output power density 1-150mW/cm of described HONGGUANG or near infrared light 2
4. laser power therapeutic instrument according to claim 1, it is characterized in that: the light that described laser beam emitting device sends is blue light, described blue light source wavelength is 400-490nm, described blue light output power density 1-150mW/cm 2
5. laser power therapeutic instrument according to claim 1 and 2, it is characterized in that: the core diameter of described optical fiber and one-time treatment optical fiber is 1-5000 μ m.
CN 201320232221 2013-05-02 2013-05-02 Laser photodynamic therapeutic instrument Expired - Lifetime CN203220691U (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105167846A (en) * 2015-09-11 2015-12-23 西安交通大学第一附属医院 Semiconductor blue laser surgical system
CN107626046A (en) * 2017-10-27 2018-01-26 贵阳中医学院 Phototherapeutic device and method for perifolliculitis capitis abscedens et suffodiens
CN107684668A (en) * 2017-05-23 2018-02-13 西安雅泽泰克医疗科技有限公司 Laser therapeutic apparantus and spinal cord restorative procedure
CN112451859A (en) * 2020-11-23 2021-03-09 昆明医科大学 Brain glioma photodynamic direct irradiation treatment device
CN112516462A (en) * 2020-11-24 2021-03-19 深圳罗兹曼国际转化医学研究院 Photoelectric combined instrument and photodynamic therapeutic apparatus

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105167846A (en) * 2015-09-11 2015-12-23 西安交通大学第一附属医院 Semiconductor blue laser surgical system
CN107684668A (en) * 2017-05-23 2018-02-13 西安雅泽泰克医疗科技有限公司 Laser therapeutic apparantus and spinal cord restorative procedure
CN107684668B (en) * 2017-05-23 2020-04-07 西安雅泽泰克医疗科技有限公司 Laser therapeutic apparatus and spinal cord repair method
CN107626046A (en) * 2017-10-27 2018-01-26 贵阳中医学院 Phototherapeutic device and method for perifolliculitis capitis abscedens et suffodiens
CN112451859A (en) * 2020-11-23 2021-03-09 昆明医科大学 Brain glioma photodynamic direct irradiation treatment device
CN112516462A (en) * 2020-11-24 2021-03-19 深圳罗兹曼国际转化医学研究院 Photoelectric combined instrument and photodynamic therapeutic apparatus

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