CN202699684U - Device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors - Google Patents
Device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors Download PDFInfo
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- CN202699684U CN202699684U CN 201220175849 CN201220175849U CN202699684U CN 202699684 U CN202699684 U CN 202699684U CN 201220175849 CN201220175849 CN 201220175849 CN 201220175849 U CN201220175849 U CN 201220175849U CN 202699684 U CN202699684 U CN 202699684U
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- sleeve pipe
- peripheral blood
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- pipe
- inflammatory factors
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Abstract
The utility model relates to a device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors. The device is characterized by comprising a vacuum aspirator I (1), a centrifuge pipe (2) and a vacuum aspirator II (3), wherein the vacuum aspirator I (1) comprises a casing pipe I (1.1) and a piston I (1.2), the piston I (1.2) is arranged in the casing pipe I (1.1), and a flexible pipe (1.3) penetrates into the piston I (1.2). The vacuum aspirator II (3) comprises a casing pipe II (3.1) and a piston II (3.2), the piston II (3.2) is arranged in the casing pipe II (3.1), and the bottoms of the casing pipe I (1.1) and the casing pipe II (3.1) can be matched with the top of the centrifuge pipe (2) in threaded mode. The device for the in-vitro induction of the self peripheral blood of the patients to generate the high-concentration anti-inflammatory factors can effectively reduce the contact between blood and air and the possibility of bacterial contamination, and is easy and fast to operate.
Description
Technical field
This utility model relates to the device that a kind of external evoked patient self peripheral blood produces the high concentration anti-inflammatory factors, is used for osteoarthritis treatment.
Background technology
Human peripheral blood can produce the serum that contains the high concentration anti-inflammatory factors external after inducing, this antiinflammatory serum is recycled in patient's the articular cavity, can stop further developing and significantly improving symptom of the osteoarthritis state of an illness.
This process relates to syringe and extracts patient's peripheral blood; Peripheral blood is injected the container with induced material; Blood in the container makes it produce anti-inflammatory factors in external evoked cultivation; Adopt centrifugal method that serum is separated with hemocyte; Draw the serum part and installed to juxtaposition cryopreservation in the preservation pipe in rear minute.Whole process need uses multiple device, organically cooperates and lack between these existing apparatus, so that the operation complicated is difficult for grasping.In addition, a plurality of steps relate to blood or serum and contact with air, cause easily germ contamination.
The utility model content
The purpose of this utility model structurally overcomes above-mentioned deficiency, provides complete external evoked patient self peripheral blood of a cover to produce the device of high concentration anti-inflammatory factors.This covering device can avoid preparing the inconvenience that multiple dispersal device brings; The each several part reasonable combination of device, easy to operate; Reduce the chance that contacts of blood and air, reduced the probability of germ contamination; Can induce patient self peripheral blood in external generation high concentration anti-inflammatory factors.
The purpose of this utility model is achieved in that
The external evoked patient of this utility model self peripheral blood produces the device of high concentration anti-inflammatory factors, it comprises the vacuum suction apparatus I, centrifuge tube and vacuum suction apparatus II, described vacuum suction apparatus I comprises sleeve pipe I and piston I, described piston I is located in the sleeve pipe I, be installed with flexible pipe in the described piston I, the top of described centrifuge tube is with lid, described vacuum suction apparatus II comprises sleeve pipe II and piston II, described piston II is located in the sleeve pipe II, the bottom of described sleeve pipe II is provided with suction attachment, the bottom of described suction attachment is connected to suction pipe, and described sleeve pipe I and sleeve pipe II bottom all can cooperate with the screw top of centrifuge tube.
The bottom of described sleeve pipe I is protruded and is provided with the female thread I, and the bottom of described sleeve pipe II is protruded and is provided with the female thread II, and the top end opening of described centrifuge tube also is provided with external screw thread, and female thread I, female thread II all can cooperate with external screw thread.
Have air-vent on the described lid, described sleeve pipe II lower sides has filtering holes, is respectively equipped with air filter film and air filtration filler in air-vent and the filtering holes, and the aperture of air filter film and air filtration filler is all less than 0.22 μ m.
The centre of described sleeve pipe I also is provided with spacing ring.
The outer race of described suction attachment has germ tight filter.
The bottom of described suction pipe is bent upwards into hook-shaped.
The bottom of described centrifuge tube is placed with some glass beads.
The device that the external evoked patient of this utility model self peripheral blood produces the high concentration anti-inflammatory factors has the following advantages:
The device that this external evoked patient self peripheral blood produces the high concentration anti-inflammatory factors changes vacuum suction apparatus I, centrifuge tube and vacuum suction apparatus II, centrifuge tube into removable structure, the blood that the vacuum suction apparatus I is extracted out can be delivered directly to and be preinstalled with in the centrifuge tube of inducing peripheral blood to produce the anti-inflammatory factors material, just can directly carry out external evoked cultivation to the blood in the centrifuge tube after subsequently the vacuum suction apparatus I being taken apart, effectively reduce blood and contact with air.It is centrifugal that the rear centrifuge tube of cultivation end can directly be put centrifuge, and serum is separated with hemocyte.Then use the vacuum suction apparatus II with the serum sucking-off in the centrifuge tube, reinject in the serum keeping pipe, so also reduced the chance of blood and contact with air, thereby reduce the possibility of germ contamination, also can sterilizing filter be installed in suction attachment place of vacuum suction apparatus II, serum is filtered, remove possibility residual hemocyte and antibacterial.Whole operating process is simple and convenient, need not to prepare more equipment, and the operating time is shorter.
Description of drawings
Fig. 1 is the fiting relation figure that the external evoked patient of this utility model self peripheral blood produces vacuum suction apparatus I and centrifuge tube in the device of high concentration anti-inflammatory factors.
Fig. 2 is the structural representation of centrifuge tube among Fig. 1.
Fig. 3 is the fiting relation figure that the external evoked patient of this utility model self peripheral blood produces vacuum suction apparatus II and centrifuge tube in the device of high concentration anti-inflammatory factors.
Fig. 4 is the structural representation of vacuum suction apparatus II among Fig. 3.
Among the figure: vacuum suction apparatus I 1, sleeve pipe I 1.1, piston I 1.2, flexible pipe 1.3, female thread I 1.4, spacing ring 1.5;
Vacuum suction apparatus II 3, sleeve pipe II 3.1, piston II 3.2, female thread II 3.3, suction attachment 3.4, suction pipe 3.5, germ tight filter 3.6, filtering holes 3.7;
The specific embodiment
Referring to Fig. 1 to Fig. 4, this utility model relates to the device that a kind of external evoked patient self peripheral blood produces the high concentration anti-inflammatory factors, it comprises vacuum suction apparatus I 1, centrifuge tube 2 and vacuum suction apparatus II 3, described vacuum suction apparatus I 1 comprises sleeve pipe I 1.1 and piston I 1.2, described piston I 1.2 is located in the sleeve pipe I 1.1, and two ends are exposed to sleeve pipe I 1.1, can in sleeve pipe I 1.1, move up and down, the center of described piston I 1.2 is installed with a flexible pipe 1.3, the two ends of flexible pipe 1.3 are exposed to piston I 1.2, its the upper end with join with venipuncture needle, the bottom protrusion of described sleeve pipe I 1.1 also is provided with female thread I 1.4, the centre of described sleeve pipe I 1.1 also is provided with a spacing ring 1.5, this spacing ring 1.5 can be spacing to the bottom of piston I 1.2, and when piston I 1.2 moved up blood drawing, spacing ring 1.5 can block piston I 1.2, guarantee to extract the blood of fixed volume, can prevent that it is pulled out sleeve pipe I 1.1 simultaneously.
The top end opening of described centrifuge tube 2 is provided with external screw thread 2.1, the bottom of centrifuge tube 2 is placed with some glass beads 2.2, described glass bead 2.2 can induce peripheral blood to produce the anti-inflammatory factors of high concentration, the top of centrifuge tube 2 is with lid 2.3, have air-vent 2.4 on the described lid 2.3, be provided with air filter film in this air-vent 2.4, the aperture of air filter film is less than 0.22 μ m, pass through with the permission air free, and prevent that antibacterial from passing through.
Described vacuum suction apparatus II 3 comprises sleeve pipe II 3.1 and piston II 3.2, described piston II 3.2 is located in the sleeve pipe II 3.1, and the upper end is exposed to sleeve pipe II 3.1, can in sleeve pipe II 3.1, move up and down, the bottom protrusion of described sleeve pipe II 3.1 also is provided with female thread II 3.3, the bottom of described sleeve pipe II 3.1 is provided with suction attachment 3.4, the bottom of described suction attachment 3.4 is connected to suction pipe 3.5, the bottom of described suction pipe 3.5 is bent upwards into hook-shaped, the outer race of described suction attachment 3.4 has germ tight filter 3.6, this germ tight filter 3.6 can be removed hemocyte that may be residual in the serum and the antibacterial that may pollute, described sleeve pipe II 3.1 bottoms have filtering holes 3.7 near on the sidewall at female thread II 3.3 places, when this filtering holes 3.7 can be avoided vacuum suction apparatus II 3 suction in sleeve pipe II 3.1 interior formation negative pressure, be provided with the air filtration filler in the described filtering holes 3.7, the aperture of air filtration filler is passed through to allow air free, and is prevented that antibacterial from passing through less than 0.22 μ m.
Described sleeve pipe I 1.1 bottoms can cooperate with the external screw thread 2.1 of centrifuge tube 2 by the female thread I, and sleeve pipe II 3.1 bottoms also can cooperate with the external screw thread 2.1 of centrifuge tube 2 by female thread II 3.3.
The device of this external evoked patient self peripheral blood generation high concentration anti-inflammatory factors in use, the sleeve pipe I of vacuum suction apparatus I 1 is threaded connection with centrifuge tube 2, only need flexible pipe 1.3 is connected venipuncture needle, pull up piston I 1.2 behind the insertion blood vessel blood directly is drawn in the centrifuge tube 2.After exhausting the sleeve pipe I is separated, 2.3 pairs of blood of cover lid carry out inducing culture.At last lid 2.3 is opened, the sleeve pipe II 3.1 of vacuum suction apparatus II 3 is joined with centrifuge tube 2 screw threads, just can serum be taken out by suction pipe 3.5, because the terminal crooked of suction pipe 3.5 upwards arranges, suction pipe 3.5 just in time is positioned at the top of hemocyte face, can be to the interference of cell generation of interfaces and with the hemocyte sucking-off.After sucking, again serum is injected the serum keeping pipe 4 rearmounted low temperature of sealing (80 C °) and deposit.
Vacuum suction apparatus I 1 and centrifuge tube 2 are assembled into one in advance, vacuum suction apparatus II 3 and suction pipe 3.5 are assembled into one in advance, these two parts and lid 2.3, germ tight filter 3.6, serum keeping pipe 4 are divided in the plastic bag of good seal, take oxirane or radiation sterilization to sterilize.
Claims (5)
1. external evoked patient self peripheral blood produces the device of high concentration anti-inflammatory factors, it is characterized in that: it comprises vacuum suction apparatus I (1), centrifuge tube (2) and vacuum suction apparatus II (3), described vacuum suction apparatus I (1) comprises sleeve pipe I (1.1) and piston I (1.2), described piston I (1.2) is located in the sleeve pipe I (1.1), be installed with flexible pipe (1.3) in the described piston I (1.2), the top of described centrifuge tube (2) is with lid (2.3), described vacuum suction apparatus II (3) comprises sleeve pipe II (3.1) and piston II (3.2), described piston II (3.2) is located in the sleeve pipe II (3.1), the bottom of described sleeve pipe II (3.1) is provided with suction attachment (3.4), the bottom of described suction attachment (3.4) is connected to suction pipe (3.5), and described sleeve pipe I (1.1) and sleeve pipe II (3.1) bottom all can cooperate with the screw top of centrifuge tube (2);
Have air-vent (2.4) on the described lid (2.3), described sleeve pipe II (3.1) lower sides has filtering holes (3.7), be respectively equipped with air filter film and air filtration filler in air-vent (2.4) and the filtering holes (3.7), the aperture of air filter film and air filtration filler is all less than 0.22 μ m;
The bottom of described centrifuge tube (2) is placed with some glass beads (2.2).
2. a kind of external evoked patient self peripheral blood according to claim 1 produces the device of high concentration anti-inflammatory factors, it is characterized in that: the bottom protrusion of described sleeve pipe I (1.1) also is provided with female thread I (1.4), the bottom protrusion of described sleeve pipe II (3.1) also is provided with female thread II (3.3), the top end opening of described centrifuge tube (2) also is provided with external screw thread (2.1), and female thread I (1.4), female thread II (3.3) all can cooperate with external screw thread (2.1).
3. a kind of external evoked patient self peripheral blood according to claim 1 produces the device of high concentration anti-inflammatory factors, and it is characterized in that: the centre of described sleeve pipe I (1.1) also is provided with spacing ring (1.5).
4. a kind of external evoked patient self peripheral blood according to claim 1 produces the device of high concentration anti-inflammatory factors, and it is characterized in that: the outer race of described suction attachment (3.4) has germ tight filter (3.6).
5. a kind of external evoked patient self peripheral blood according to claim 1 produces the device of high concentration anti-inflammatory factors, and it is characterized in that: the bottom of described suction pipe (3.5) is bent upwards into hook-shaped.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN 201220175849 CN202699684U (en) | 2012-04-24 | 2012-04-24 | Device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors |
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CN 201220175849 CN202699684U (en) | 2012-04-24 | 2012-04-24 | Device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors |
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CN202699684U true CN202699684U (en) | 2013-01-30 |
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CN 201220175849 Withdrawn - After Issue CN202699684U (en) | 2012-04-24 | 2012-04-24 | Device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102631717A (en) * | 2012-04-24 | 2012-08-15 | 祁小平 | Device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors |
-
2012
- 2012-04-24 CN CN 201220175849 patent/CN202699684U/en not_active Withdrawn - After Issue
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102631717A (en) * | 2012-04-24 | 2012-08-15 | 祁小平 | Device for in-vitro induction of self peripheral blood of patients to generate high-concentration anti-inflammatory factors |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
AV01 | Patent right actively abandoned |
Granted publication date: 20130130 Effective date of abandoning: 20131127 |
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RGAV | Abandon patent right to avoid regrant |