Background technology
The preservation of biochemical reagents and reaction need be satisfied certain temperature condition usually; It is exactly a kind ofly to carry out temperature controlled instrument for the preservation of biochemical reagents and reaction that thermostat metal is bathed, and it is widely used in the degenerative treatments of preservation and reaction, nucleic acid and the protein of the preservation of various biological samples, various enzymes, preparatory sex change that PCR reacts (PCR), electrophoresis and serum and solidifies etc.
Present thermostat metal is bathed; Form by the multiple arrangement of being close to successively from top to bottom in structure aspects; Comprise pedestal, pad, heating and cooling parts, thermal component; One side of thermal component is provided with supply unit, display floater, and the opposite side of thermal component is provided with a ventilating fan, and ventilating fan is embedded in the casing.The thermostat metal of this prior art is bathed and aspect adjustment, is had defective, mainly shows as the heat conduction lack of homogeneity, warming and cooling rate is slow.
(1) heat conduction lack of homogeneity.
Because pad is generally made of aluminum, and the coefficient of heat conduction of aluminium be merely K=237W/mK (watt/Mi Du), can not be with heat evenly diffusion rapidly, so its heat conduction uniformity is good inadequately; On the other hand; Generally there is the space in contact-making surface between pedestal, pad, heating and cooling parts, the thermal component; For example if certain parts surface is uneven, its with just can't fit fully between the parts up and down, the heat between the part face of applying passes through the transfer of air of heat conductivility difference; The heat of the part of fitting is that the heat-conducting effect of different parts will exist than big-difference so through the metal transmission of the face of mutual applying.The heat conduction that above-mentioned a variety of causes causes is inhomogeneous, makes that the preservation or the reaction condition that are positioned over the reagent of diverse location in the same pedestal are inconsistent, causes follow-up biochemical test to carry out smoothly.
(2) warming and cooling rate is slow.
Need make an explanation to the heating and cooling mode that thermostat metal is bathed here.As far as a specific cooling piece, no matter be in heating or refrigerating state, the absolute value P of its upper and lower surfaces temperature difference is constant.Prior art is exactly through cooling piece being taked different step modes, being utilized its constant temperature difference absolute value to control the heating and cooling to pedestal.As need heat up to pedestal, then, make the underlaying surface temperature of cooling piece be lower than the upper surface temperature to the energising of cooling piece forward, because the temperature difference is constant,, can make the upper surface temperature rise to target temperature so through the underlaying surface temperature that progressively raises; As need lower the temperature to pedestal, then cooling piece is oppositely switched on, make the upper surface temperature of cooling piece be lower than underlaying surface temperature, because the temperature difference is constant, through progressively reducing the upper surface temperature, can make underlaying surface temperature drop to target temperature so.
In the heating and cooling process that thermostat metal is bathed, the running of ventilating fan can help the realization of heating and cooling.Because fin contacts with cooling piece, its temperature is consistent with the underlaying surface temperature of cooling piece, when ventilating fan turns round, will make between fin and the external environment condition and form cross-ventilation, carries out heat exchange.When pedestal is heated up; Need the underlaying surface temperature of cooling piece to raise; If this moment, the temperature of cooling piece lower surface was lower than environment temperature, the running of ventilating fan can make the temperature of fin and cooling piece lower surface rise to environment temperature as early as possible so, therefore can improve intensification efficient; When pedestal is lowered the temperature; Need the underlaying surface temperature of cooling piece to reduce; If this moment, the temperature of cooling piece lower surface was higher than environment temperature, the running of ventilating fan can make the temperature of fin and cooling piece lower surface drop to environment temperature as early as possible so, therefore can improve cooling efficient.But prior art takes to install in the metal bath lateral location mode of a ventilating fan, and its heat exchanger effectiveness is not high, makes the heating and cooling efficient of pedestal lower.
Except two point defects of said temperature adjusting aspect, the metal bath of prior art also haves much room for improvement aspect ease for use.Because during the heating of the reagent in the pedestal that thermostat metal is bathed, reagent just can heat up, and produces steam; When steam runs into cold base seat lid; Just can produce a large amount of steam and condensed water, the condensate return that forms when steam can cause the pollution of reagent in the pedestal in pedestal the time; On the other hand; When opening base seat lid, the condensed water on the base seat lid can cause the waste of reagent under the marginal flow of pedestal; Simultaneously; Condensed water flows in the element of pedestal below, the element in can etching apparatus, damages circuit, make security that thermostat metal bathes with all can not get guarantee service life.
Therefore need a kind of new thermostat metal to bathe, can improve the adjustment ability, and strengthen ease for use.
The utility model content
The purpose of the utility model is to provide a kind of thermostat metal to bathe, and is intended to solve the lower problem of adjustment ability, ease for use that thermostat metal is bathed in the prior art.
In order to realize the purpose of utility model, said thermostat metal is bathed and is comprised pedestal, heating and cooling parts, thermal component, comprises that also one is used for the conducting strip of heat exchange, and its upper and lower surfaces is fitted its coefficient of heat conduction K>237W/mK with pedestal, heating and cooling parts respectively.
Wherein, the constituent of said conducting strip comprises the metal material of at least a coefficient of heat conduction K>237W/mK.Wherein, the metal material of at least a coefficient of heat conduction K>237W/mK is called thermo-sensitive material.Also promptly, conducting strip is the sheet that thermo-sensitive material is processed.
Wherein, the constituent of said conducting strip is a copper; Or the constituent of the said conducting strip alloy that to be copper form with arbitrary metal or nonmetallic materials.Wherein, the alloy of copper and/or copper and arbitrary metal or nonmetallic materials composition is called the superconduction hot material.Also promptly, the sheet processed for the superconduction hot material of conducting strip.
Wherein, the minimum dimension of said conducting strip and base bottom surface consistent size.
Wherein, scribble thermal interfacial material at least one contact-making surface between said pedestal, conducting strip, heating and cooling parts, the thermal component.
Wherein, said thermal interfacial material is heat conductive silica gel, heat-conducting silicone grease or heat conduction adhesive tape.
Wherein, also be provided with an insulating pad between said pedestal and the conducting strip, its metal or nonmetallic materials by thermal conductivity factor K≤237 W/mK are processed.
Wherein, the bottom that said thermostat metal is bathed is equipped with at least one ventilating fan, and is relative with the position of thermal component.
Wherein, the side of said thermostat metal bath also is equipped with at least one ventilating fan.
Wherein, the pedestal top that said thermostat metal is bathed is provided with an anti-condensation device, and the reagent stored position in itself and the pedestal is relative.
Wherein, said anti-condensation device comprises the heater that at least one is used to heat, and at least one is used for the temperature sensor of temperature detection.
Wherein, also be provided with one on the pedestal that said thermostat metal is bathed and be used to the pad that prevents that condensed water from producing, the shape of said pad, size are all consistent with pedestal upper surface, and it independently exists or combines with pedestal upper surface.
Wherein, be provided with the collar that prevents under the condensation flow around the said pedestal, its specification and pedestal side are complementary.
By on can know that the utility model is through being provided with one deck conducting strip between pedestal and heating and cooling parts, and on the contact-making surface between pedestal, conducting strip, heating and cooling parts, the thermal component, apply thermal interfacial material, strengthened the heat conduction uniformity; Between pedestal and conducting strip, insulating pad is set, has strengthened the heat insulation function of pedestal; Ventilating fan is changed to the bottom, and increase the ventilating fan number, improved heating and cooling efficient; Anti-condensation device and pad are set above pedestal, and around pedestal, are provided with the collar, improved the ease for use that thermostat metal is bathed.
The specific embodiment
For the purpose, technical scheme and the advantage that make the utility model is clearer,, the utility model is further elaborated below in conjunction with accompanying drawing and embodiment.
Fig. 1 shows the profile that thermostat metal is bathed in the utility model.This thermostat metal bathroom facilities has good heat conduction uniformity, and it comprises pedestal, heating and cooling parts, thermal component, comprises that also one is used for the conducting strip of heat exchange.The upper and lower surfaces of this conducting strip is fitted its coefficient of heat conduction K>237W/mK with pedestal, heating and cooling parts respectively.
The internal structure that below will in a plurality of embodiment, bathe this thermostat metal is set forth in detail.
Fig. 2 shows the structure that thermostat metal is bathed among the embodiment of the utility model, comprises pedestal 1, conducting strip 2, heating and cooling parts 3, thermal component 4 and other each building blocks, and its detailed structure is following:
(1) pedestal 1, is used for placing the reagent pipe that holds reagent, and will pass to the heat transferred reagent pipe of pedestal 1.
(2) conducting strip 2, are used for the heat that passes to conducting strip 2 is passed to pedestal 1 uniformly, make pedestal 1 be heated evenly.
(3) the heating and cooling parts 3; The lower surface of the upper surface of heating and cooling parts 3 and conducting strip 2 fits tightly; Be used for the reagent in the reagent pipe in the pedestal 1 is heated or freezes; The heat of heating and cooling parts 3 passes to pedestal 1 uniformly through conducting strip 2, and pedestal 1 passes to the reagent pipe with temperature again.
(4) thermal component 4, and the upper surface of the lower surface of heating and cooling parts 3 and thermal component 4 fits tightly, and are used for energy in the quick device for transferring, make heating and cooling parts 3 lower surfaces reach required temperature fast.
(5) ventilating fan 5, and air in the realization equipment and extraneous cross-ventilation make fin play the effect of quick heat radiating or refrigeration.
(6) display floater 6, are used for showing the various running statuses that thermostat metal is bathed.
(7) supply unit 7, and bathing for thermostat metal provides required electric current.
Wherein, pedestal 1 links together with thermal component 4, and heating and cooling parts 3 and conducting strip 2 are pressed between pedestal 1 and the thermal component 4.
In the utility model, all there are multiple feasible scheme in the material of conducting strip 2, size, shape etc.
About the material of conducting strip 2, its constituent comprises the metal material of at least a coefficient of heat conduction K greater than 237W/mK.The metal material of at least a coefficient of heat conduction K>237W/mK is called thermo-sensitive material.Also promptly, conducting strip is the sheet that thermo-sensitive material is processed.Wherein, when the material of conducting strip 2 is: during alloy that copper and/or copper and arbitrary metal or nonmetallic materials are formed, this is called the superconduction hot material alloy of copper and/or copper and arbitrary metal or nonmetallic materials composition.Also promptly, the sheet processed for the superconduction hot material of conducting strip.
Therefore, the material of conducting strip 2 both can be certain single metal material, also can be alloy.Be that conducting strip can be the sheet that thermo-sensitive material or superconduction hot material are processed, set forth as follows respectively:
If the thermo-sensitive material of single metal material, the thermo-sensitive material of the metal material of coefficient of heat conduction K >=237W/mK comprises: silver (K=429W/mK), copper (K=401W/mK), gold (K=317W/mK).In one embodiment, the material of conducting strip 2 is single argent, utilizes the good thermal conductivity and the ductility of silver, and the thickness d of conducting strip 2 is 1mm~3mm.In another embodiment, conducting strip 2 is the thermo-sensitive material of single metallic copper or the sheet that the superconduction hot material is processed, and it utilizes the good thermal conductivity of copper can be so that the heat transmission is even, and conducting strip 2 is selected the thermo-sensitive material of copper material or the sheet that the superconduction hot material is processed for use.The optimum thickness d of conducting strip 2 is 2mm~3mm.
If the thermo-sensitive material of alloy or superconduction hot material then comprise a variety of situation.In one embodiment; Utilize the cheapness of good thermal conductivity of copper and aluminium, the thermo-sensitive material of the alloy of conducting strip 2 use copper aluminium or the sheet that the superconduction hot material is processed, the proportion of copper and aluminium can be selected as required; For example be 30% and 70%, the optimum thickness d=3mm of conducting strip 2.In another embodiment, utilize the cheapness of good thermal conductivity of copper and iron, conducting strip 2 uses the alloy thermo-sensitive material of copper iron or the sheet that the superconduction hot material is processed, and the best proportion of copper and iron for example is 70% and 30%, the optimum thickness d=2mm of conducting strip 2.
About the size of conducting strip 2, its minimum dimension and base bottom surface consistent size.In one embodiment, as shown in Figure 3, the size of conducting strip 2 and the size of base bottom surface are identical.Pedestal 1 is placed on the conducting strip 2, and conducting strip 2 is close together through bolted mode with pedestal 1.In another embodiment, as shown in Figure 4, conducting strip 2 is of a size of the length of side long X of each limit than base bottom surface, and for example X=1cm can guarantee that equally heat can pass to each point of base bottom surface.
About the shape of conducting strip 2, can choose as required.In one embodiment, the shape of conducting strip is as shown in Figure 3, and conducting strip 2 is a plane, and pedestal 1 is close to conducting strip 2, and pedestal 1 is connected with conducting strip 2 through bolted mode.In another embodiment; The shape of conducting strip 2 is as shown in Figure 4, and conducting strip 2 is protruding all around groove shape, and pedestal 1 is comprised in the groove of conducting strip 2; Pedestal 1 is close to the bottom of conducting strip 2 grooves, and pedestal 1 is connected with conducting strip 2 through bolted mode.
In the utility model, the connected mode of pedestal 1 and thermal component 4 has multiple.In one embodiment, pedestal 1 closely is connected through bolted mode with thermal component 4.In another embodiment, pedestal 1 also can pass through the pin ways of connecting with thermal component 4.
In the utility model,, can bathe on the contact-making surface between each parts at thermostat metal and apply thermal interfacial material in order further to improve the inhomogeneity problem of heat conduction.About the coating position of thermal interfacial material, and the material selection of thermal interfacial material itself, specification be provided with etc., all has kinds of schemes.
Coating position about thermal interfacial material:
In first embodiment, as shown in Figure 5, all contact-making surfaces between pedestal 1, conducting strip 2, heating and cooling parts 3, the thermal component 4 all scribble thermal interfacial material 8.
In a second embodiment, scribble thermal interfacial material 8 on two contact-making surfaces between pedestal 1, conducting strip 2, the heating and cooling parts 3.
In the 3rd embodiment, scribble thermal interfacial material 8 on two contact-making surfaces between conducting strip 2, heating and cooling parts 3, the thermal component 4.
In the 4th embodiment, only on the contact-making surface between pedestal 1 and the conducting strip 2, scribble thermal interfacial material 8.
In the 5th embodiment, only between conducting strip 2 and heating and cooling parts 3, scribble thermal interfacial material.
In the 6th embodiment, only between heating and cooling parts 3 and thermal component 4, scribble thermal interfacial material.
Material selection about thermal interfacial material 8: can be heat conductive silica gel, heat-conducting silicone grease or heat conduction adhesive tape, the preferred material of thermal interfacial material 8 be a heat-conducting silicone grease in the utility model.
Specification setting about thermal interfacial material 8: the utility model is mainly considered its thickness, as long as can evenly be coated on the contact-making surface, the space is filled up, thereby heat conduction is more evenly got final product.In one embodiment, the thickness of above-mentioned thermal interfacial material 8 can be 0.05mm≤d≤0.4mm.In a preferred embodiment, the thickness of thermal interfacial material 8 is 0.15mm.
In order to make pedestal have better heat insulation effect, the utility model further proposes improvement project, between pedestal 1 and conducting strip, also is provided with an insulating pad.
In one embodiment, as shown in Figure 6.The lower surface of pedestal 1 is close to insulating pad 9 upper surfaces, and the lower surface of insulating pad 9 is close to the upper surface of conducting strip.
Wherein, the material of above-mentioned insulating pad 9 can be chosen the material of thermal conductivity factor K≤237W/mK and process, and this material can be a metal material, also can be nonmetallic materials.Thickness d≤the 1mm of insulating pad.
Wherein, the material of above-mentioned insulating pad 9 can be that single metal is processed, and also can adopt alloy to process.The best preferred material of the material of the utility model insulating pad 9 is metallic aluminiums.
Wherein, the size of the size of above-mentioned insulating pad 9 and pedestal is just coincide.When conducting strip 2 was groove structure, insulating pad 9 was pressed in the groove of pedestal 1 and conducting strip 2; When conducting strip 2 was planar structure, pedestal 1 lower surface was close to the upper surface of insulating pad 9, and the lower surface of insulating pad 9 is close to the upper surface of conducting strip 2, and insulating pad 9 is pressed between pedestal 1 and the conducting strip 2.
In another embodiment, as shown in Figure 7.The lower surface of pedestal 1 is close to the upper surface of insulating pad 9, and the lower surface of insulating pad 9 is close to the upper surface of making conducting strip 2, and the lower surface of conducting strip 2 is close to the upper surface of heating and cooling parts 3, and the lower surface of heating and cooling parts 3 is close to the upper surface of thermal component 4.Scribble thermal interfacial material 8 between above-mentioned two faces being close to.Like this, thermostat metal is bathed and not only have the heat conduction uniformity but also have good heat insulation effect.
In order to improve heating and cooling efficient, the utility model is further made improvement on the basis of previous embodiment, and the angle from fan installation site, number of fans proposes new scheme and embodiment respectively.
Scheme one has made the installation site of ventilating fan 5 into bottom from side of the prior art, relative with the position of thermal component 4, like Fig. 8, shown in Figure 9.Like this, when thermal component 4 work, the core position of heating is just facing to ventilating fan, and the ventilating fan running just can be taken away great amount of heat, thereby realizes the fast cooling to pedestal 1.
Thermostat metal as shown in Figure 8 is bathed, and compares with the embodiment of Fig. 2, has made the installation site of ventilating fan 5 into bottom from side of the prior art, and is relative with the position of thermal component 4.
Thermostat metal as shown in Figure 9 is bathed, and compares with the embodiment of Fig. 5, has made the installation site of ventilating fan 5 into bottom from side of the prior art, and is relative with the position of thermal component 4.
Scheme two, the number of increase ventilating fan 5 utilizes the mode that a plurality of ventilating fans turn round simultaneously to improve generation cooling efficient.About the quantity that increases, the utility model does not limit.
Thermostat metal shown in figure 10 is bathed, and compares with the embodiment of Fig. 8, and two ventilating fans 5 are installed in the bottom.
Thermostat metal shown in figure 11 is bathed, and compares with the embodiment of Fig. 8, in side and bottom a ventilating fan 5 is installed simultaneously.
Thermostat metal shown in figure 12 is bathed, and compares with the embodiment of Fig. 9, and two ventilating fans 5 are installed in the bottom.
In order to strengthen ease for use, the utility model is further made improvement on the basis of previous embodiment, is mainly preventing to propose new scheme and embodiment aspect reagent loss, the condensed water generation.
Scheme one is provided with an anti-condensation device above the pedestal 1 that thermostat metal is bathed, the reagent stored position in itself and the pedestal 1 is relative, and this anti-condensation device can generate heat.When temperature of reagent was higher than room temperature in the pedestal, anti-condensation device heating made its temperature higher than reagent temperature, and reagent just can not volatilize or condensation like this, has effectively prevented reagent loss, and has avoided the generation of condensed water.In one embodiment, this anti-condensation device comprises the heater that at least one is used to heat, and at least one is used for the temperature sensor of temperature detection.
Thermostat metal shown in figure 13 is bathed, and compares with the embodiment of Fig. 2, above pedestal 1, is provided with a heat lid 10.
Thermostat metal shown in figure 14 is bathed, and compares with the embodiment of Fig. 5, above pedestal 1, is provided with a heat lid 10.
Thermostat metal shown in figure 15 is bathed, and compares with the embodiment of Figure 12, above pedestal 1, is provided with a heat lid 10.
Similar with Figure 13, Figure 14, Figure 15, the utility model can all be made identical improvement on aforesaid other embodiment bases, and above pedestal 1, being provided with should heat lid 10, does not give unnecessary details here.
Scheme two also is provided with one and is used to the pad that prevents that condensed water from producing on the pedestal 1 that thermostat metal is bathed.This pad adopts thermal conductivity factor little, and is corrosion-resistant and have certain absorptive material and process, and therefore can prevent the generation of condensed water, for example asbestos, rubber etc.
Shown in figure 16, be provided with a pad 11 on the pedestal 1 that thermostat metal is bathed, the shape of this pad 11, size, the shape of this pad, size are all consistent with pedestal 1 upper surface, and it independently exists or combines with pedestal 1 upper surface.
Scheme three is provided with the collar that prevents under the condensation flow around pedestal 1.This collar adopts thermal conductivity factor little equally, and is corrosion-resistant and have certain absorptive material and process, and therefore can prevent under the condensation flow, for example asbestos, rubber etc.The specification of this collar and pedestal 1 side are complementary, and also promptly: if pedestal 1 is square, this collar also is square so; If pedestal is circular, this collar also just is circular.
Shown in figure 17, around pedestal 1, be provided with a collar 12 that prevents under the condensation flow, be arranged on the position parallel with the pedestal upper edge.Should be noted that in the utility model that the position of the collar 12 can be provided with flexibly, embodiment shown in Figure 17 should not regard the restriction to protection domain as.
Should be noted that the utility model typical application but be not limited to the utilization in thermostat metal is bathed that other similar principles or scheme also should be included in protection domain of the utility model and so on.
The above is merely the preferred embodiment of the utility model; Not in order to restriction the utility model; Any modification of being done within all spirit and principles at the utility model, be equal to replacement and improvement etc., all should be included within the protection domain of the utility model.