CN201988225U - Chromatographic column - Google Patents
Chromatographic column Download PDFInfo
- Publication number
- CN201988225U CN201988225U CN2011200836710U CN201120083671U CN201988225U CN 201988225 U CN201988225 U CN 201988225U CN 2011200836710 U CN2011200836710 U CN 2011200836710U CN 201120083671 U CN201120083671 U CN 201120083671U CN 201988225 U CN201988225 U CN 201988225U
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- CN
- China
- Prior art keywords
- chromatographic column
- distribution plate
- cylindrical shape
- liquid outlet
- cup dolly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Abstract
The utility model discloses a chromatographic column. The chromatographic column comprises a round base which is provided with a liquid outlet. A cylindrical column is installed on the round base in sealing mode, the liquid outlet is arranged at the center of the round base, guide grooves communicated with the liquid outlet are evenly distributed on the round base, and an upper layer round distribution plate and a lower layer round distribution plate which are formed by stainless steel sintered meshes are arranged inside the cylindrical column. Due to the application of the upper layer round distribution plate and the lower layer round distribution plate, sample adding liquid can be added evenly on the upper surface of gel, and the uniformity of pressure which causes the liquid to seep under the gel is also ensured. The structure is capable of enhancing continuity, uniformity and stability of sample adding.
Description
Technical field
The utility model relates to a kind of separator of biological chemical field, particularly a kind of chromatographic column that is used for separation chemistry product and natural products.
Background technology
Chromatographic isolation is the present most effective a kind of method of purification means in pharmaceutical industry, biological chemical field, is one of the separation of natural products and important means of other high purity substance preparation, uses more and more widely.Chromatographic column is the key equipment that the various liquid chromatogram of system is separated, the laboratory is often all smaller with the chromatographic column diameter, the liquid phase sample that is added on the gel surface will soon radial diffusion, in order to improve very big that its chromatographic column diameter of output does, continuity, uniformity, the stability of improving application of sample seem extremely important for improving separative efficiency and product quality for the chromatographic column of using on the industrial production.
Summary of the invention
The purpose of this utility model is to provide a kind of chromatographic column, and it can improve continuity, uniformity and the stability of application of sample, is fit to suitability for industrialized production and uses, and helps improving separative efficiency and product quality.
The technical solution of the utility model is: a kind of chromatographic column, it comprises the cup dolly with liquid outlet, the cylindrical shape cylinder is installed in sealing on cup dolly, it is characterized in that: the center of cup dolly is provided with liquid outlet, the guiding gutter that equally distributed connection liquid outlet is arranged above the cup dolly is equipped with upper strata circular distribution plate and the lower floor's circular distribution plate that is made of stainless steel sintering net in the cylindrical shape column body.
Described guiding gutter comprise some cannelures and some be the bar-shaped trough of the radial arrangement in the center of circle with the liquid outlet.
Described cylindrical shape cylinder is by transparent acrylic material, on cylindrical shape cylinder top is flange, the upper and lower side of cylindrical shape cylinder all has the ring packing rubber cushion, by the lead screw more than 3 cup dolly, ring packing rubber cushion, cylindrical shape cylinder and flange is superimposed.
Described stainless steel sintering net all is to be formed by 5～10 layers of stainless (steel) wire sintering.
On the top of flange is circular upper cover, and hollow leading screw is installed at the circular upper cover center, and hollow leading screw lower end connects upper strata circular distribution plate, and the lifting handwheel that can improve and reduce upper strata circular distribution plate height is set on hollow leading screw.
Moving of chromatographic column installed 3～4 universal wheels in the bottom of cup dolly for convenience.
Advantage of the present utility model is: comprise upper strata circular distribution plate and lower floor's circular distribution plate in the cylindrical shape cylinder of the present utility model, the guiding gutter that equally distributed connection liquid outlet is arranged above the cup dolly, it can guarantee the even adding of application of sample liquid at the gel upper surface, also guaranteed simultaneously the uniformity of exudation pressure below gel, this structure can be improved continuity, uniformity and the stability of application of sample.At the circular upper cover center hollow leading screw is installed, hollow leading screw lower end connects upper strata circular distribution plate, the lifting handwheel that can improve and reduce upper strata circular distribution plate height is set on hollow leading screw, the application of sample pipe can be connected the upper end of hollow leading screw and realize continuous application of sample, can adjust the technological requirement that upper strata circular distribution plate height is fit to the different-thickness gel by the lifting handwheel.
Description of drawings
Fig. 1 is the utility model chromatographic column perspective view;
Fig. 2 is the utility model chromatographic column decomposing state perspective view;
Fig. 3 is the cup dolly perspective view of the utility model chromatographic column;
Among the figure: 1. circular upper cover, 2. hollow leading screw, 3. lifting handwheel, 4. upper strata circular distribution plate, 5. flange, 6. seal gasket, 7. cylindrical shape cylinder, 8. lead screw, 9. lower floor's circular distribution plate, 10. guiding gutter, 11. cup dollies, 12. universal wheels, 13. liquid outlets.
The specific embodiment
Below in conjunction with the drawings and specific embodiments the utility model is described further.
As Fig. 1, Fig. 2 and shown in Figure 3, a kind of chromatographic column, it comprises the cup dolly 12 with liquid outlet 13, be to be the cylindrical shape cylinder 7 that transparent acrylic material is made above the ring packing rubber cushion 6 ring packing rubber cushions 6 on cup dolly 12, it above the cylindrical shape cylinder 7 ring packing rubber cushion 6, it above the ring packing rubber cushion 6 flange 5, by 8 lead screw 8 with cup dolly 11, ring packing rubber cushion 6, cylindrical shape cylinder 7 and flange 5 are superimposed, the center of cup dolly 12 is provided with liquid outlet 13, the guiding gutter 10 that equally distributed connection liquid outlet 13 is arranged above the cup dolly 12, described guiding gutter 10 comprise that 26 cannelures and 16 are the bar-shaped trough of the radial arrangement in the center of circle with liquid outlet 13.At cylindrical shape cylinder 7 inner upper strata circular distribution plate 4 and the lower floor's circular distribution plates 9 that constitute by stainless steel sintering net that are equipped with.Described stainless steel sintering net all is to be formed by 7 layers of stainless (steel) wire sintering.On the top of flange 5 are circular upper covers 1, and hollow leading screw 2 is installed at circular upper cover 1 center, and hollow leading screw 2 lower ends connect upper strata circular distribution plate 4, and the lifting handwheel 3 that can improve and reduce upper strata circular distribution plate 4 height is set on hollow leading screw 2.4 universal wheels 12 are installed in bottom at cup dolly 11.
Claims (6)
1. chromatographic column, it comprises the have liquid outlet cup dolly (12) of (13), go up sealing at cup dolly (12) cylindrical shape cylinder (7) is installed, it is characterized in that: the center of cup dolly (12) is provided with liquid outlet (13), the guiding gutter (10) that equally distributed connection liquid outlet (13) is arranged above the cup dolly (12) is at inner upper strata circular distribution plate (4) and the lower floor's circular distribution plate (9) that is made of stainless steel sintering net that be equipped with of cylindrical shape cylinder (7).
2. chromatographic column according to claim 1 is characterized in that: described guiding gutter (10) comprise some cannelures and some be the bar-shaped trough of the radial arrangement in the center of circle with liquid outlet (13).
3. chromatographic column according to claim 1 and 2, it is characterized in that: described cylindrical shape cylinder (7) is by transparent acrylic material, on cylindrical shape cylinder (7) top is flange (5), the upper and lower side of cylindrical shape cylinder (7) all has ring packing rubber cushion (6), by the lead screw more than 3 (8) cup dolly (11), ring packing rubber cushion (6), cylindrical shape cylinder (7) and flange (5) is superimposed.
4. chromatographic column according to claim 1 and 2 is characterized in that: described stainless steel sintering net all is to be formed by 5～10 layers of stainless (steel) wire sintering.
5. chromatographic column according to claim 3, it is characterized in that: on the top of flange (5) is circular upper cover (1), hollow leading screw (2) is installed at circular upper cover (1) center, hollow leading screw (2) lower end connects upper strata circular distribution plate (4), and the lifting handwheel (3) that can improve and reduce upper strata circular distribution plate (4) height is set on hollow leading screw (2).
6. chromatographic column according to claim 5 is characterized in that: 3～4 universal wheels (12) are installed in the bottom at cup dolly (11).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200836710U CN201988225U (en) | 2011-03-28 | 2011-03-28 | Chromatographic column |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011200836710U CN201988225U (en) | 2011-03-28 | 2011-03-28 | Chromatographic column |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201988225U true CN201988225U (en) | 2011-09-28 |
Family
ID=44664730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011200836710U Expired - Fee Related CN201988225U (en) | 2011-03-28 | 2011-03-28 | Chromatographic column |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201988225U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103736297A (en) * | 2012-10-17 | 2014-04-23 | 奇复康药物研发(苏州)有限公司 | Sample adding device |
| CN104364645A (en) * | 2012-06-21 | 2015-02-18 | 通用电气健康护理生物科学股份公司 | Chromatography column and method of conducting maintenance on a chromatography column |
-
2011
- 2011-03-28 CN CN2011200836710U patent/CN201988225U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104364645A (en) * | 2012-06-21 | 2015-02-18 | 通用电气健康护理生物科学股份公司 | Chromatography column and method of conducting maintenance on a chromatography column |
| CN104364645B (en) * | 2012-06-21 | 2016-10-19 | 通用电气健康护理生物科学股份公司 | Chromatographic column and the method that chromatographic column is safeguarded |
| CN103736297A (en) * | 2012-10-17 | 2014-04-23 | 奇复康药物研发(苏州)有限公司 | Sample adding device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20110928 Termination date: 20140328 |