CN201555849U - Disc type colloidal gold immunochromatography combined detection plate - Google Patents
Disc type colloidal gold immunochromatography combined detection plate Download PDFInfo
- Publication number
- CN201555849U CN201555849U CN2009200947788U CN200920094778U CN201555849U CN 201555849 U CN201555849 U CN 201555849U CN 2009200947788 U CN2009200947788 U CN 2009200947788U CN 200920094778 U CN200920094778 U CN 200920094778U CN 201555849 U CN201555849 U CN 201555849U
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- Prior art keywords
- test paper
- plate
- detection
- disc type
- colloidal gold
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- Expired - Fee Related
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- 238000001514 detection method Methods 0.000 title claims abstract description 25
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 title claims abstract description 17
- 238000003317 immunochromatography Methods 0.000 title abstract 2
- 238000012360 testing method Methods 0.000 claims abstract description 26
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000000020 Nitrocellulose Substances 0.000 claims description 5
- 229920001220 nitrocellulos Polymers 0.000 claims description 5
- 230000005855 radiation Effects 0.000 claims description 3
- 238000005516 engineering process Methods 0.000 abstract description 7
- 239000000523 sample Substances 0.000 description 18
- 239000010931 gold Substances 0.000 description 5
- 229910052737 gold Inorganic materials 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 238000003018 immunoassay Methods 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Abstract
The utility model provides a disc type joint detection plate applying the colloidal gold immunochromatography technology, which comprises a foundation plate and a detection test paper; the foundation plate is of a disc type structure consisting of a body and a plate cover, and a plurality of test paper inserting grooves which are radially and symmetrically distributed by taking the circle center as the midpoint are arranged on the body; the detection test paper is inserted in the groove of the body; the center of the plate cover is provided with a sample adding hole, and the middle ring is provided with a display window. The test paper is arranged radially and fixed in the body. The utility model discloses can be according to actual need, random adjustment examined object quantity, the application of sample once carries out one step of detection to one kind or more than one kind fast, has characteristics quick, sensitive, easy and simple to handle, with low costs, that need not the professional and detect.
Description
Technical field
The utility model provides a kind of disc type colloidal gold immunochromatographimethod joint-detection plate, and the immune detection device of one or more antigens of fast detecting or antibody belongs to the immunology detection technical field simultaneously.
Background technology
The colloidal gold immunochromatographimethod technology is a kind of solid phase labelling immunoassay technology that several different methods such as colloidal gold-labeled method, immunoassay technology and chromatographic analysis technology are organically combined, have highly sensitive, high specificity, good reproducibility, degree of accuracy height, easy and simple to handle, detect characteristics fast and accurately, advantages such as instrument and equipment that need not be complicated, have bigger practical value, be particularly suitable for on-the-spot fast monitored.But existing colloidal gold strip is to operate respectively, detect respectively according to detected object not of the same race mostly, and inconvenient, it is higher that total detects cost during operating cost.Pertinent literature is not by retrieval seen the bibliographical information of relevant combined type colloidal gold immunochromatographimethod joint-detection plate.
Summary of the invention
The utility model provides a kind of disc type colloidal gold immunochromatographimethod joint-detection plate, and purpose is can be fast and detect one or more antigens or antibody simultaneously.
The utility model is achieved through the following technical solutions:
Check-out console is made of foundation plate and detection test paper; Foundation plate constitutes disk structure by body and plate lid two parts, and being provided with on body with its center of circle is that mid point is a plurality of detection test paper plug-in mounting grooves that radiation is symmetrically distributed; Detecting test paper is inserted in the groove of body; The center of plate lid is provided with sample and adds hand-hole, in be equipped with display window.Detect test paper and be fixed in body interior, be radial arrangement, the sample preparation pad is positioned at the body circle centre position, and when body was connected with the plate lid, sample preparation pad transmitting plate lid exposed to the open air out, the convenient testing sample that drips.
Described detection test paper utilizes collaurum sandwich method principle to make, testing sample is dripped on the sample preparation pad that detects test paper, because the capillarity sample will move to the water sucting plate end along test paper, when moving to gold mark bond pad, immunogene in the sample and gold mark probe generation idiosyncrasy, form " gold mark probe-immunogene " compound, continue reach, when moving to detection line, corresponding immunogene combination with the bag quilt forms " gold mark probe-immunogene-corresponding immunogene " compound and condenses colour developing; On the contrary,, then can not form " gold mark probe-immunogene " compound if there is not immunogene to be measured in the sample, detection line can not with corresponding immunogene combination, thereby can not condense colour developing.
According to actual needs, by substituting detection line, nature controlling line encrusting substance and the golden composition of marking probe on the nitrocellulose filter, can be made into the different test paper that detect, realize that one goes on foot detection.
Good effect of the present utility model is: the limitation that has overcome the single variety detectable, employing colloidal gold immunochromatographimethod technology (GICA) can be according to actual needs, adjust detected object quantity at random, an application of sample, the device that fast one or more detected objects is carried out step detection.Simple in structure, the processing ease of the utility model, and high specificity, highly sensitive, easily store, need not the technical skill personnel operation, and readability as a result.Owing to save repeated operation and material, so its production cost will be lower than the cost of each individual event check-out console sum.Need not specific apparatus, reach easy and simple to handle, quick, sensitive, special, purpose accurately.Be applicable to that multiple occasion such as field quick detection and epidemiology survey detects.
Description of drawings
Fig. 1, the utility model structural representation;
Fig. 2, the utility model test paper distribution schematic appearance.
1. body; 2. test paper 3. plates cover; 4. display window; 5. sample adds hand-hole; 6. groove; 7. handle pad; 8. nitrocellulose filter.
Embodiment
According to shown in Figure 1, the utility model is made up of foundation plate and detection test paper, wherein, foundation plate is that disk structure comprises that body 1 and plate cover 3 two parts and constitute, and being provided with on body 1 with its center of circle is that mid point is a plurality of detection test paper plug-in mounting grooves 6 that radiation is symmetrically distributed; Detect in the groove 6 that test paper is inserted into body 1 (referring to Fig. 2); The center of circle of plate lid 3 is provided with sample and adds hand-hole 5, in be equipped with display window 4.The sample preparation pad 7 that detects test paper 2 is positioned at the position, the center of circle of foundation plate, and nitrocellulose filter 8 is corresponding with the display window 4 of plate lid 3.
During use, be fixed in the groove 6 of body 1, be radial arrangement detecting test paper 2, sample preparation pad 1 is positioned at the circle centre position of body 1, buckles plate lid 3, and sample preparation pad 1 transmitting plate lid 3 exposes to the open air out, the convenient testing sample that drips, nitrocellulose filter 8 is corresponding with the display window 4 of plate lid 3.
Claims (2)
1. a disc type colloidal gold immunochromatographimethod joint-detection plate is characterized in that comprising foundation plate and detects test paper; Foundation plate constitutes disk structure by body and plate lid two parts, and being provided with on body with its center of circle is that mid point is a plurality of detection test paper plug-in mounting grooves that radiation is symmetrically distributed, and detects test paper and is inserted in the groove of body; The center of plate lid is provided with sample and adds hand-hole, in be equipped with display window.
2. disc type colloidal gold immunochromatographimethod joint-detection plate according to claim 1 is characterised in that: the sample preparation pad that detects test paper is positioned at the position, the center of circle of foundation plate, and nitrocellulose filter is corresponding with the display window of plate lid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009200947788U CN201555849U (en) | 2009-11-18 | 2009-11-18 | Disc type colloidal gold immunochromatography combined detection plate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009200947788U CN201555849U (en) | 2009-11-18 | 2009-11-18 | Disc type colloidal gold immunochromatography combined detection plate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201555849U true CN201555849U (en) | 2010-08-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009200947788U Expired - Fee Related CN201555849U (en) | 2009-11-18 | 2009-11-18 | Disc type colloidal gold immunochromatography combined detection plate |
Country Status (1)
| Country | Link |
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| CN (1) | CN201555849U (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101949930A (en) * | 2010-09-13 | 2011-01-19 | 无锡市金坤生物工程有限公司 | Disc for fast detecting mycotoxin indexes |
| CN106222081A (en) * | 2016-08-31 | 2016-12-14 | 北京中科圆融生物科技发展有限公司 | Single centre multi-channel assembled detection device |
| CN106442978A (en) * | 2016-10-08 | 2017-02-22 | 北京国科华仪科技有限公司 | Y-shaped two-channel fluorescence immunochromatography test strip and preparation method thereof |
| CN107727842A (en) * | 2017-11-13 | 2018-02-23 | 山东省环境保护科学研究设计院 | A kind of preparation and application of clenbuterol hydrochloride full constituent residual joint inspection test card |
| CN109187945A (en) * | 2018-09-29 | 2019-01-11 | 厦门大学 | A kind of laying method of colloid gold test paper on CD |
| WO2019109365A1 (en) * | 2017-12-06 | 2019-06-13 | 深圳市易瑞生物技术股份有限公司 | Immunochromatography detection device for high-flux agricultural veterinary drug residues |
| CN116359498A (en) * | 2023-02-23 | 2023-06-30 | 兰州兽研生物科技有限公司 | Immune chromatography test paper card for joint inspection of foot-and-mouth disease, african swine fever, swine fever and porcine reproductive and respiratory syndrome virus antibodies |
-
2009
- 2009-11-18 CN CN2009200947788U patent/CN201555849U/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101949930A (en) * | 2010-09-13 | 2011-01-19 | 无锡市金坤生物工程有限公司 | Disc for fast detecting mycotoxin indexes |
| CN106222081A (en) * | 2016-08-31 | 2016-12-14 | 北京中科圆融生物科技发展有限公司 | Single centre multi-channel assembled detection device |
| CN106222081B (en) * | 2016-08-31 | 2019-01-15 | 北京中科圆融生物科技发展有限公司 | The multi-channel assembled detection device of single centre |
| CN106442978A (en) * | 2016-10-08 | 2017-02-22 | 北京国科华仪科技有限公司 | Y-shaped two-channel fluorescence immunochromatography test strip and preparation method thereof |
| CN107727842A (en) * | 2017-11-13 | 2018-02-23 | 山东省环境保护科学研究设计院 | A kind of preparation and application of clenbuterol hydrochloride full constituent residual joint inspection test card |
| WO2019109365A1 (en) * | 2017-12-06 | 2019-06-13 | 深圳市易瑞生物技术股份有限公司 | Immunochromatography detection device for high-flux agricultural veterinary drug residues |
| CN109187945A (en) * | 2018-09-29 | 2019-01-11 | 厦门大学 | A kind of laying method of colloid gold test paper on CD |
| CN109187945B (en) * | 2018-09-29 | 2019-07-12 | 厦门大学 | A kind of laying method of colloid gold test paper on CD |
| CN116359498A (en) * | 2023-02-23 | 2023-06-30 | 兰州兽研生物科技有限公司 | Immune chromatography test paper card for joint inspection of foot-and-mouth disease, african swine fever, swine fever and porcine reproductive and respiratory syndrome virus antibodies |
| CN116359498B (en) * | 2023-02-23 | 2024-06-11 | 兰州兽研生物科技有限公司 | Immune chromatography test paper card for joint inspection of foot-and-mouth disease, african swine fever, swine fever and porcine reproductive and respiratory syndrome virus antibodies |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Xu Hui Inventor after: Wang Xiaocong Inventor after: Gao Pujun Inventor after: Xu Hong Inventor after: Xu Guoliang Inventor before: Xu Hui Inventor before: Wang Xiaocong Inventor before: Gao Fujun Inventor before: Xu Hong Inventor before: Xu Guoliang |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: XU HUI WANG XIAOCONG GAO FUJUN XU HONG XU GUOLIANG TO: XU HUI WANG XIAOCONG GAO PUJUN XU HONG XU GUOLIANG |
|
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20100818 Termination date: 20121118 |