CN201520758U - Foam return fermentation system - Google Patents

Foam return fermentation system Download PDF

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Publication number
CN201520758U
CN201520758U CN 200920187963 CN200920187963U CN201520758U CN 201520758 U CN201520758 U CN 201520758U CN 200920187963 CN200920187963 CN 200920187963 CN 200920187963 U CN200920187963 U CN 200920187963U CN 201520758 U CN201520758 U CN 201520758U
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CN
China
Prior art keywords
foam
tank
return tank
fermentation
foam return
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN 200920187963
Other languages
Chinese (zh)
Inventor
贡国鸿
余增亮
郑之明
袁成凌
王丽
王鹏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Plasma Physics of CAS
Original Assignee
Institute of Plasma Physics of CAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Plasma Physics of CAS filed Critical Institute of Plasma Physics of CAS
Priority to CN 200920187963 priority Critical patent/CN201520758U/en
Application granted granted Critical
Publication of CN201520758U publication Critical patent/CN201520758U/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/02Means for regulation, monitoring, measurement or control, e.g. flow regulation of foam
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10Separation or concentration of fermentation products

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The utility model discloses a foam return fermentation system, comprising a fermenter which is internally provided with a stirrer. The system is characterized in that: the fermenter is provided with an air inlet and a fermentation liquid outlet, and the upper part of the fermenter is connected to the upper part of a primary foam return tank by a foam and thallus pipeline; the bottom part of the primary foam return tank is connected at the upper part of a secondary foam return tank by a pipeline; the secondary foam return tank is provided with a sterile air inlet; the upper part of the primary foam return tank is connected with the upper part of a foam product separating tank by a foam pipeline; and the foam product separating tank is provided with an extractant inlet and a fermentation product outlet. The foam return fermentation system has simple structure, effectively controls fermentation foams, reduces the loss of thallus cells and fermentation products, adds no defoamer in the fermentation process, and can separate the fermentation products in an online manner, thus being applicable to fermentation production in scale and the like, and being a high-efficiency and practical device.

Description

A kind of foam backflow fermentation system
Technical field:
The utility model relates generally to the microbial fermentation apparatus field, relates in particular to a kind of foam backflow fermentation system.
Technical background:
In aerobic fermentation, because ventilation and stirring can produce foam in the fermenting process, too much foam is to hinder the important factor that fermentation is normally carried out, and overflowing of excess foam take away fermented liquid, somatic cells and tunning, and cause fermentation to pollute easily; Because the existence of tensio-active agent makes the fermented liquid foam that produces become stable, this bubble-related issues are particularly outstanding in bio-surfactant is produced, and limited the large-scale production of whole industry; At present, eliminate the foamy method and generally adopt methods such as physical method, mechanical means and adding defoamer, but shortcoming is arranged all, physical method and mechanical means defoaming effect are not obvious, adding defoamer can influence the transmission of oxygen, thereby influences bacterial metabolism, and the effect of these methods is very limited when eliminating the bio-surfactant barm, do not reach control, eliminate foam, the purpose that fermentation is normally gone on.
The utility model content:
The utility model is in order to remedy the defective of prior art; a kind of foam backflow fermentation system is provided, and loss, the fermenting process that has solved the control of barm in the fermenting process, somatic cells and tunning need add defoamer, problems such as mass-producing fermentative production are separated, are not suitable for to the tunning difficulty.
The utility model is achieved through the following technical solutions:
A kind of foam backflow fermentation system, include fermentor tank, agitator is installed in the fermentor tank, it is characterized in that: described fermentor tank is provided with gas inlet and fermented liquid outlet, and fermentor tank top by foam and thalline pipe connection to one-level foam return tank top, described one-level foam return tank bottom by pipe connection in secondary foam return tank top, described secondary backflow return tank is provided with the sterile air inlet, and secondary backflow return tank forms circulation loop by liquefier and thalline pipe connection in fermentor tank, described one-level foam return tank top is by foam pipe connection foam product separating tank top, and described foam product separating tank is provided with extraction agent inlet and tunning outlet.
Described a kind of foam backflow fermentation system is characterized in that: described one-level foam return tank bottom is higher than secondary foam return tank top.
Secondary foam return tank of the present utility model feeds sterile air; make the mycetome cell foam that overflows in the fermentor tank under the promotion of sterile air, enter the liquefaction of one-level return tank froth breaking; liquefier enters the secondary return tank under action of gravity; return fermentor tank relaying supervention ferment at this by the aseptic compressed air pressure; too much foam can enter the foam product tripping device product is separated; utilize aseptic compressed air as foam liquefaction, backflow power, be applicable to the mass-producing fermentative production.
When being used for the serious biological fermentation process of foam such as bio-surfactant, can control too much foam from the one-level return tank, to flow in the product separating tank, extract target product in the foam by suitable method again.
Advantage of the present utility model:
The utility model is simple in structure; but loss, the fermenting process of effectively having controlled barm, minimizing somatic cells and tunning need not to add defoamer, tunning ON-LINE SEPARATION, are applicable to mass-producing fermentative production etc., be a kind of efficient, practical new installation.
Description of drawings:
Accompanying drawing is the utility model structural representation.
Embodiment:
A kind of foam backflow fermentation system, include fermentor tank 1, fermentor tank 1 is provided with gas inlet 5 and fermented liquid outlet 6, and by pipe connection in one-level foam return tank 2, one-level foam return tank 2 by pipe connection in secondary foam return tank 3, secondary backflow fermentor tank 3 is provided with sterile air and feeds mouth 7, and form circulation loop in fermentor tank 1 by pipe connection, described one-level foam return tank 2 also is connected with foam product separating tank 4 by pipeline, and foam product separating tank 4 is provided with extraction agent inlet 8 and tunning outlet 9.
Described one-level foam return tank 2 bottoms are higher than secondary foam return tank 3 tops, its principle is: utilize under the effect of pneumatics and gravity, with lather collapse, liquefaction, the liquefaction fermented liquid, somatic cells is gone into secondary foam return tank 3 by action of gravity through pipeline and valve controlling flow, close the valve between one-level foam return tank 2 and the secondary foam return tank 3 then, the aseptic compressed air that utilizes secondary foam return tank 3 to feed pushes back fermentor tank 1 relaying supervention ferment with the liquid in the secondary foam return tank 3 by pipeline, too much foam spills into product separating tank 4 through one-level foam return tank 2 by pipeline, in the extraction agent inlet 8 of product separating tank 4, add extraction agent, extract the product of taking out of in the foam with suitable separation method.

Claims (2)

1. foam backflow fermentation system, include fermentor tank, agitator is installed in the fermentor tank, it is characterized in that: described fermentor tank is provided with gas inlet and fermented liquid outlet, and fermentor tank top by foam and thalline pipe connection to one-level foam return tank top, described one-level foam return tank bottom by pipe connection in secondary foam return tank top, described secondary backflow return tank is provided with the sterile air inlet, and secondary backflow return tank forms circulation loop by liquefier and thalline pipe connection in fermentor tank, described one-level foam return tank top is by foam pipe connection foam product separating tank top, and described foam product separating tank is provided with extraction agent inlet and tunning outlet.
2. a kind of foam backflow fermentation system according to claim 1 is characterized in that: described one-level foam return tank bottom is higher than secondary foam return tank top.
CN 200920187963 2009-09-30 2009-09-30 Foam return fermentation system Expired - Fee Related CN201520758U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200920187963 CN201520758U (en) 2009-09-30 2009-09-30 Foam return fermentation system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200920187963 CN201520758U (en) 2009-09-30 2009-09-30 Foam return fermentation system

Publications (1)

Publication Number Publication Date
CN201520758U true CN201520758U (en) 2010-07-07

Family

ID=42506936

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200920187963 Expired - Fee Related CN201520758U (en) 2009-09-30 2009-09-30 Foam return fermentation system

Country Status (1)

Country Link
CN (1) CN201520758U (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102061282A (en) * 2010-11-29 2011-05-18 安徽帝元生物科技有限公司 Fermentation device
CN103614281A (en) * 2013-10-12 2014-03-05 北京市捷博特能源技术有限公司 Lipopeptide fermentation apparatus through foam circulation, and process
CN111849737A (en) * 2020-06-10 2020-10-30 北京首钢朗泽新能源科技有限公司 Fermentation system and method

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102061282A (en) * 2010-11-29 2011-05-18 安徽帝元生物科技有限公司 Fermentation device
CN103614281A (en) * 2013-10-12 2014-03-05 北京市捷博特能源技术有限公司 Lipopeptide fermentation apparatus through foam circulation, and process
CN111849737A (en) * 2020-06-10 2020-10-30 北京首钢朗泽新能源科技有限公司 Fermentation system and method
CN111849737B (en) * 2020-06-10 2021-05-04 北京首钢朗泽新能源科技有限公司 Fermentation system and method

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20100707

Termination date: 20180930