CN201131997Y - A dry power inhalation device - Google Patents

A dry power inhalation device Download PDF

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Publication number
CN201131997Y
CN201131997Y CNU2007200995458U CN200720099545U CN201131997Y CN 201131997 Y CN201131997 Y CN 201131997Y CN U2007200995458 U CNU2007200995458 U CN U2007200995458U CN 200720099545 U CN200720099545 U CN 200720099545U CN 201131997 Y CN201131997 Y CN 201131997Y
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CN
China
Prior art keywords
gear
inhaler
dry powder
medicine
combination
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Expired - Fee Related
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CNU2007200995458U
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Chinese (zh)
Inventor
魏海
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China National Academy Nanotechnology & Engineering
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China National Academy Nanotechnology & Engineering
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Priority to CNU2007200995458U priority Critical patent/CN201131997Y/en
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Publication of CN201131997Y publication Critical patent/CN201131997Y/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The utility model relates to a dry powder inhaler, which is characterized in that the dry powder inhaler is composed of an inhaler outer casing, an internal gear combination of the inhaler, a medicine foil combination and a control combination. The dry powder inhaler has the advantages that firstly, the inhaler can be reused, and is convenient for counting, and the medicine foil can be taken out or newly loaded and reused if necessary; secondly, the dry powder inhaler has the advantages of convenient carrying, quick use and easy operation; thirdly, CFC fluoric ether kind is not included, and pure medicine can be used; fourthly, the dry powder inhaler is not required to be maintained; fifthly, the flow rate of the dry powder particles is matched with the air inhalation flow rate of the user through the medicament particles dispersed by using the kinetic energy of air actively inhaled by a user, the drugs are output in the form of dry powder particles, therefore, after the dry powder medication leave from the inhaler, the size of the micro particles cannot be rapidly changed because of change of time and distance, and the dry powder particles are more stable; sixthly, because the gas flow rate is different from the air current way, less amount is left at the oropharynx part during the process of inhaling the dry powder.

Description

A kind of powder inhaler
(1) technical field:
This utility model relates to a kind of inhaler device, particularly a kind of powder inhaler.
(2) background technology:
The anapnotherapy great advantage of clinical medicine is that medicine can directly act on target organ by higher concentration (being generally more than 10% of administration total amount) fast, and medicine sucks back and the rapid onset of corresponding receptors bind, so the local drug concentration height, good effect.As suck behind the β2Ji Dongji and just can produce tangible bronchorelaxing activity in several minutes, but used drug dose is much smaller than the systemic administration amount, general suction treatment dose only is 1/tens of a systemic administration dosage, avoid or reduced the issuable side effect of whole body administration, the therapeutic index height, clinical safety is good.
Medicine is to enter in the body with the form output of aerosol (aerosol) and with breathing by inhalation apparatus when sucking treatment.Aerosol has huge contact surface, helps medicine and contacts with airway surface and play a role, but have cohesion simultaneously.Aerocolloidal flowability depends on that the external world gives its initial velocity, and its settlement action is followed the Stoke law substantially, and promptly sedimentation velocity is directly proportional with granular mass.
Therefore clinical therapeutic effect directly depends on the difference of the size, form, molecular weight, electric charge, moisture absorption etc. of inside compound mode, the drug particles of delivery device.With regard to granular size, the drug particles of diameter 1~5 μ m is the most suitable, be referred to as to suck granule, greater than the granule of 5 μ m then the overwhelming majority be trapped within pars oralis pharyngis, finally enter in the body through swallowing, though and can reach lower respiratory tract less than the granule of 0.5 μ m, 90% microgranule excretes with expiration again when moisture is breathed.The shortcoming that existing Diskus commonly used exists is: carry inconvenience, use trouble of operation, often need repairing dry powder particle instability etc.This is the problem that this problem need solve.
(3) summary of the invention:
Characteristics such as the purpose of this utility model is to provide a kind of powder inhaler, and it has the user of being convenient to carries, convenient to use, and dry powder particle is more stable, and is economical and practical.
The technical solution of the utility model: a kind of dry powder inhaler device, it is characterized in that it is made of inhaler shell, the combination of inhaler internal gear, the combination of medicine paper tinsel and control combination, on the said inhaler shell suction nozzle is arranged, the combination of said inhaler internal gear comprises master gear, from gear, groove gear, roller bearing and counting gear, master gear and groove gears engaged, 2 engagements of groove gear are from gear; Medicine chaff in the said medicine paper tinsel combination is to be fit together by two aluminium foil surfaces, one aluminium foil surface is terminal to be connected from gear shaft, another aluminium foil surface end is connected in main gear shaft by fixed dam and roller bearing, and two aluminium foil surface boundary ends of applying are in the junction of groove gear and DPI suction nozzle; Counting gear is engaged in the lower shaft of master gear; Said control combination comprises pressure slide bar gear bar and spring, and an end of spring is fixed, and the other end connects pressure slide bar gear bar, and pressure slide bar gear bar is meshed with master gear according to gear; Each medicated powder bubble-cap is when the groove of process groove gear in the combination of medicine paper tinsel, and the medicated powder bubble-cap that is separated two aluminium foil surfaces is aimed at suction nozzle.
Have protection medicine chaff to twine the curved baffle of typing in the above-mentioned said medicine paper tinsel combination, curved baffle enclosure respectively is wrapped in medicine chaff on the gear shaft and the medicine chaff on the medicine paper tinsel roller bearing.
On the above-mentioned said inhaler shell registration window is arranged, the registration window places counting gear engagement master gear to embody the volume range degree place that aluminum foil strip is wrapped in main gear shaft.
Operation principle of the present utility model: this case discloses a kind of powder inhaler, this device relies on the strength of being pushed generation by the user, drive the incompatible dry-powder medicament of opening and transmitting in the medicine paper tinsel of setting dosage of gear train of device inner setting, the medicine chaff locatees the opening encapsulation paillon foil by the groove of gear, the user begins to be undertaken air-breathing by the suction nozzle in the device, the dry-powder medicament of setting dosage is sucked pulmonary, thereby reach therapeutic effect.The structure of this case has strengthened the gas flow rate degree and has sucked dry powder particle more fully so that suck air-flow.The gear combination of this case by setting reaches the purpose that transmits dry-powder medicament in the medicine paper tinsel.
Superiority of the present utility model is: (1) this inhaler can be reused, and convenient counting as needs, can take out the medicine paper tinsel or filling repeated use again; (2) Diskus have easy to carry, use quick, processing ease; (3) do not contain CFC fluoroalkane hydro carbons, can use pure medicine; (4) need not keep in repair; (5) initiatively suck the kinetic energy dispersion medicine microgranule of air by user, the flow velocity of dry powder particle and the inspiratory flow rate of user match, and medicine is exported with the dry powder particle form, therefore rapid variation can not take place because of the variation of time and distance in the size of dry-powder medicament microparticle after leaving suction apparatus, and dry powder particle is more stable; (6) because gas flow rate and streamer mode different, pars oralis pharyngis retention amount is less when using dry powder doses to suck.
(4) description of drawings:
Accompanying drawing 1 is the mounted inside perspective view of the related a kind of dry powder inhaler device of this utility model.
Wherein: 1 is suction nozzle, and 2 is the groove gear, and 3 is fixed dam, and 4 is roller bearing, 5 is master gear, and 5-1 is a main gear shaft, and 6 is from gear, 6-1 is from gear shaft, and 7 is medicine paper tinsel roller bearing, and 8 is the medicine chaff, 8-1 is an aluminium foil surface of medicine chaff, and 8-2 is another aluminium foil surface of medicine chaff, and 9 is the medicated powder bubble-cap, 10-1 and 10-2 are curved baffle, and 11 is slide bar, and 12 is spring, 13 is the inhaler shell, and 14 is counting gear, and 15 is registration window (at the shell of device).
Wherein the dry-powder medicament of 8 medicine paper tinsel included 20-200 grain whites or off-white color is sealed in aluminium foil In the bar, this aluminum foil strip is wound in medicine paper tinsel roller bearing 7.
Wherein the registration window shows residual drug. When use will be shown as when last dosage is 5~0 red Look, warning residue dosage is few.
(5) specific embodiment:
Embodiment: a kind of dry powder inhaler device (see figure 1), it is characterized in that it is made of inhaler shell 13, the combination of inhaler internal gear, the combination of medicine paper tinsel and control combination, on the said inhaler shell 13 suction nozzle 1 is arranged, the combination of said inhaler internal gear comprises master gear 5, from gear 6, groove gear 2, roller bearing 4 and counting gear 14, master gear 5 and 2 engagements of groove gear, 2 engagements of groove gear are from gear 6; Medicine chaff 8 in the said medicine paper tinsel combination is to be fit together by two aluminium foil surface 8-1 and 8-2, one aluminium foil surface 8-1 is terminal to be connected from gear shaft 6-1, another aluminium foil surface 8-2 end is connected in main gear shaft 5-1 by fixed dam 3 and roller bearing 4, and two aluminium foil surface boundary ends of applying are in the junction of groove gear 2 and DPI suction nozzle 1; Counting gear 14 is engaged in the lower shaft of master gear 5; Said control combination comprises pressure slide bar gear bar 11 and spring 12, and an end of spring 12 is fixed, and the other end connects pressure slide bar gear bar 11, and pressure slide bar gear bar 11 is meshed with master gear 5 according to gear; Each medicated powder bubble-cap 9 is when the groove of process groove gear 2 in the combination of medicine paper tinsel, and the medicated powder bubble-cap 9 that is separated two aluminium foil surfaces is aimed at suction nozzles 1.
Have protection medicine chaff 8 to twine the curved baffle 10-1 and the 10-2 of typing in the above-mentioned said medicine paper tinsel combination, curved baffle 10-1 and 10-2 enclosure respectively are wrapped in medicine chaff 8-1 on the gear shaft 6-1 and medicine chaff 8 (see figure 1)s on the medicine paper tinsel roller bearing 7.
On the above-mentioned said inhaler shell 13 registration window 15 is arranged, registration window 15 places counting gear 14 engagement master gears 5 to embody the volume range degree place (see figure 1) that aluminum foil strip 8-2 is wrapped in main gear shaft 5-1.
Method of work of the present utility model may further comprise the steps:
(1) opens Diskus: press inhaler pressure slide bar 11 to the bottom, drive master gear 5, from the gear movement of gear volume 6,2 combinations of groove gear;
(2) prepare to suck: suction nozzle 1 is over against a groove at groove gear 2 places, and medicine chaff 8 dose drug in the bubble-cap 9 that is opened simultaneously is in order to sucking;
(3) suck: the user aims at suction nozzle, press the inhaler slide bar, guarantee that it is in the bottom, keep the inhaler balance and suction nozzle is contained in the inlet, when pushing the inhaler slide bar, steadily breathe and suction nozzle is put into mouth, suck medicine as far as possible, fully behind air-breathing the finishing, pressure slide bar 11 is by the automatic reposition of spring, for the use of next suction is got ready;
(4) close: behind abundant air-breathing finishing, the 11 automatic repositions of pressure slide bar, the dose drug that suction nozzle 1 place does not have in the bubble-cap of opening 9 then will be closed automatically, for the use of next suction is got ready, above-mentioned described institute when needs suck two suction medicines, repeats to get final product in steps;
(5) time spent not, all inhaler device are placed in the shell, play the effect of protection inhaler.
Above-mentioned described step (1) must guarantee as far as possible: acutely do not rock inhaler; Do not exhale facing to the inhaler suction nozzle; Guarantee that you press the inhaler slide bar when needs use medicine; Using dosage please be followed the doctor's advice.
The medicine of the opened bubble-cap dosage of inhaler during above-mentioned described step (2), and carry out and inhale preceding all preparations of medicine, have corresponding demonstration at the dosage indication window this moment, and the user only need suck medicine and get final product.
Above-mentioned described step (3) is please taken out inhaler after sucking from mouth, be sure not to go into from snuffing.
Above-mentioned described institute when needs suck two suction medicines, repeats to get final product in steps.

Claims (3)

1, a kind of dry powder inhaler device, it is characterized in that it is made of inhaler shell, the combination of inhaler internal gear, the combination of medicine paper tinsel and control combination, on the said inhaler shell suction nozzle is arranged, the combination of said inhaler internal gear comprises master gear, from gear, groove gear, roller bearing and counting gear, master gear and groove gears engaged, 2 engagements of groove gear are from gear; Medicine chaff in the said medicine paper tinsel combination is to be fit together by two aluminium foil surfaces, one aluminium foil surface is terminal to be connected from gear shaft, another aluminium foil surface end is connected in main gear shaft by fixed dam and roller bearing, and two aluminium foil surface boundary ends of applying are in the junction of groove gear and DPI suction nozzle; Counting gear is engaged in the lower shaft of master gear; Said control combination comprises pressure slide bar gear bar and spring, and an end of spring is fixed, and the other end connects pressure slide bar gear bar, and pressure slide bar gear bar is meshed with master gear according to gear; Each medicated powder bubble-cap is when the groove of process groove gear in the combination of medicine paper tinsel, and the medicated powder bubble-cap that is separated two aluminium foil surfaces is aimed at suction nozzle.
2, according to the said a kind of dry powder inhaler device of claim 1, it is characterized in that having in the combination of said medicine paper tinsel protection medicine chaff to twine the curved baffle of typing, curved baffle enclosure respectively is wrapped in medicine chaff on the gear shaft and the medicine chaff on the medicine paper tinsel roller bearing.
3, according to the said a kind of dry powder inhaler device of claim 1, it is characterized in that on the said inhaler shell registration window being arranged, the registration window places counting gear engagement master gear to embody the volume range degree place that aluminum foil strip is wrapped in main gear shaft.
CNU2007200995458U 2007-12-28 2007-12-28 A dry power inhalation device Expired - Fee Related CN201131997Y (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNU2007200995458U CN201131997Y (en) 2007-12-28 2007-12-28 A dry power inhalation device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNU2007200995458U CN201131997Y (en) 2007-12-28 2007-12-28 A dry power inhalation device

Publications (1)

Publication Number Publication Date
CN201131997Y true CN201131997Y (en) 2008-10-15

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Family Applications (1)

Application Number Title Priority Date Filing Date
CNU2007200995458U Expired - Fee Related CN201131997Y (en) 2007-12-28 2007-12-28 A dry power inhalation device

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102257546A (en) * 2008-10-24 2011-11-23 赛诺菲-安万特德国有限公司 Device for simulating the operation of a medication delivery device
CN107949409A (en) * 2015-07-20 2018-04-20 维克多瑞传送设备有限公司 Diskus

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102257546A (en) * 2008-10-24 2011-11-23 赛诺菲-安万特德国有限公司 Device for simulating the operation of a medication delivery device
CN102257546B (en) * 2008-10-24 2014-11-19 赛诺菲-安万特德国有限公司 Device for simulating the operation of a medication delivery device
CN107949409A (en) * 2015-07-20 2018-04-20 维克多瑞传送设备有限公司 Diskus
CN107949409B (en) * 2015-07-20 2020-10-20 维克多瑞传送设备有限公司 Dry powder inhaler
US10953165B2 (en) 2015-07-20 2021-03-23 Vectura Delivery Devices Limited Dry powder inhaler

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C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20081015

Termination date: 20141228

EXPY Termination of patent right or utility model