CN200957108Y - Active injection type thermotherapy probe for tumor targeted therapy - Google Patents
Active injection type thermotherapy probe for tumor targeted therapy Download PDFInfo
- Publication number
- CN200957108Y CN200957108Y CN 200620116204 CN200620116204U CN200957108Y CN 200957108 Y CN200957108 Y CN 200957108Y CN 200620116204 CN200620116204 CN 200620116204 CN 200620116204 U CN200620116204 U CN 200620116204U CN 200957108 Y CN200957108 Y CN 200957108Y
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- China
- Prior art keywords
- cavity
- outer tube
- needle tubing
- cylinder barrel
- tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 37
- 238000000015 thermotherapy Methods 0.000 title claims abstract description 27
- 239000000523 sample Substances 0.000 title claims abstract description 26
- 238000002347 injection Methods 0.000 title claims abstract description 22
- 239000007924 injection Substances 0.000 title claims abstract description 22
- 238000002626 targeted therapy Methods 0.000 title claims abstract description 15
- 238000010438 heat treatment Methods 0.000 claims abstract description 50
- 239000007788 liquid Substances 0.000 claims abstract description 30
- 239000000126 substance Substances 0.000 claims description 19
- 208000035269 cancer or benign tumor Diseases 0.000 claims description 13
- 239000000243 solution Substances 0.000 claims description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 8
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 8
- 238000003466 welding Methods 0.000 claims description 8
- 238000002512 chemotherapy Methods 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- 229960000935 dehydrated alcohol Drugs 0.000 claims description 4
- 239000011521 glass Substances 0.000 claims description 4
- 239000007943 implant Substances 0.000 claims description 4
- 239000011780 sodium chloride Substances 0.000 claims description 4
- 238000005485 electric heating Methods 0.000 claims description 3
- 239000000835 fiber Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 229910001220 stainless steel Inorganic materials 0.000 claims description 3
- 239000010935 stainless steel Substances 0.000 claims description 3
- 230000008685 targeting Effects 0.000 abstract description 3
- 210000004881 tumor cell Anatomy 0.000 abstract description 2
- 239000000945 filler Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 description 9
- 230000001225 therapeutic effect Effects 0.000 description 8
- 208000027418 Wounds and injury Diseases 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 230000006378 damage Effects 0.000 description 4
- 208000014674 injury Diseases 0.000 description 4
- 238000001959 radiotherapy Methods 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 238000005481 NMR spectroscopy Methods 0.000 description 2
- 229910000831 Steel Inorganic materials 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 239000010959 steel Substances 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 210000005239 tubule Anatomy 0.000 description 1
- 239000013585 weight reducing agent Substances 0.000 description 1
Landscapes
- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
An active injection type thermotherapy probe for tumor targeted therapy, the needle body of which comprises: a needle tube interface tube arranged at the closed end of the cavity and communicated with the cavity and a flange integrated with the open end of the cavity; the piston type propulsion pole includes: a piston head slidably mounted in the cavity, a push rod part integrated with the piston head, and a cavity formed between the cavity and the piston head; the needle tube comprises an inner tube and an outer tube, the lower end of the outer tube is a tip part, a heating cavity is arranged in the front section of the outer tube, a filler is arranged between the inner tube and the outer tube, and the upper end of the inner tube is communicated with a needle tube connector tube; the heating element and the thermocouple lead in the heating cavity are led out from the needle tube interface tube. When in use, the normal temperature liquid working medium is transmitted to the head part of the probe, heated to the required temperature by the heating element and then injected to the target area of the tumor to kill the tumor cells, and the healthy tissues are not damaged by any heat along the way; has the advantages of micro-wound, good thermal targeting, simple structure, low cost, simple and convenient operation and the like, and can be conveniently combined with other tumor treatment modes for use.
Description
Technical field
This utility model relates to a kind of injection thermotherapy probe, be particularly related to a kind of active injection thermotherapy probe that is used for neoplasm targeted therapy, this probe can with the room temperature liquid transfer to end of probe and this place adopt active parts such as electrothermal device, radio frequency, laser etc. rapidly heating and promote temperature after, again it is injected into tumor locus to be treated and implements thermotherapy and be not subjected to any hot injury along the journey health tissues.
Background technology
The high temperature thermotherapy is the another important tumor therapeuticing method after radiotherapy, chemotherapy.Now developed the thermotherapy method of the part at the human body different parts, regional deep, shallow table, limbs and the whole body etc. that use various energy effects (as microwave, radio frequency, ultrasonic, laser etc.), but these methods all are faced with a common issue with, promptly how the heat orientation is transported to the target area tumor tissues, has both effectively killed tumor and don't normal structure is caused the hot injury.Still not having a kind of method at present can thoroughly address this problem.In addition, all there is some self deficiency in above-mentioned thermotherapy method, because the interference of electromagnetic field requires very highly to thermometric, and must adopt preventer as microwave heat therapeutic; And causing the overheated pain of superficial tissue easily when alternate manner such as radio frequency, no cold water cooling such as ultrasonic, health tissues is scalded when often causing tumor to be treated still not have any fragmentation effect.Especially, these devices common ground is that complex structure, price are very expensive.Generally speaking, in the current various factors that influences the tumor thermotherapy effect, the most key heating technique just.The ideal heat request that adds accomplishes that all tumor tissues are heated to it and kill and wound more than the threshold temperature, and keeps certain hour, wiping out lesion tissue, but also will avoid the overheated and damaged of normal structure around the tumor or organ simultaneously.
Summary of the invention
The purpose of this utility model is to provide a kind of active injection thermotherapy probe that is used for neoplasm targeted therapy simple in structure, with low cost, can be used for heating to treat of each position tumor, local tumors such as deep tissue, tract are suitable for too, and can realize that the targeting heat discharges and improve therapeutic effect.Its most significant characteristics are that the health tissues along journey can not be subjected to any hot injury in the therapeutic process, and this is very favourable for clinical implementation.
The technical solution of the utility model is as follows:
The active injection thermotherapy probe that is used for neoplasm targeted therapy that this utility model provides comprises needle body part 10 and needle tubing part 20; Described needle tubing part 20 is for having the needle tubing part of heating element heater;
Described needle body part 10 comprises:
One cylinder barrel shaped cavity 1; Be installed on needle tubing mouthpiece 2 on described cylinder barrel shaped cavity 1 blind end and intracavity inter-connection described cylinder barrel shaped cavity 1; And with the into a single integrated structure flange 5 of the opening end of described cylinder barrel shaped cavity 1;
One piston type is propelled bar 3; Described piston type is propelled bar 3 and is comprised: be installed on the piston crown 31 in described cylinder barrel shaped cavity 1 inner chamber slidably; Have a graduated bar bar portion 32 that propels with piston crown 31 fuses; And be connected in the shank 33 of propelling bar bar portion 32 ends; And the cavity 4 that forms between described cylinder barrel shaped cavity 1 inner chamber and the described piston crown 31 in order to carrying liquid working medium;
Described needle tubing part 20 comprises:
Interior pipe 7 and the outer tube 6 placed with one heart, the length of pipe 7 is less than described outer tube 6 in described, pipe 7 is fixed by welding in the top with outer tube 6 in described, in pipe 7 also be fixed together with outer tube 6 in the lower end by welding, described outer tube 6 lower ends are the point that has tapering, and the preceding intrasegmental part of described outer tube 6 leaves heating chamber 9;
Filling in described, manage 7 and outer tube 6 between annulus 67 in implant;
Pipe 7 upper ends are connected with the needle tubing mouthpiece 2 of described needle body part 10 in described; Also comprise
Be placed on heating element heater and thermocouple in the heating chamber 9 of described needle tubing part 20; The annulus 67 that the lead-in wire 8 of described heating element heater and thermocouple passes between described interior pipe 7 and the outer tube 6 is drawn from needle tubing part 11 upper ends.
Described piston crown 31 is a hollow circular cylinder.Described cylinder barrel shaped cavity 1, interior pipe 7 and outer tube 6 are stainless steel part.Described cavity 4 is the cavity in order to splendid attire water, saline, ethanol, dehydrated alcohol, acetum, hydrochloric acid solution or sulfuric acid solution liquid working substance.Described cavity 4 is for containing the cavity of treatment tumor with the liquid working substance of chemotherapy medicinal liquid in order to splendid attire.Described piston type is propelled the propel bar of bar 3 for glass material.The described heating element heater that is placed in the heating chamber 9 is electric heating device, radio-frequency antenna or the laser fiber that carries external power supply.
1. before the treatment,, design concrete therapeutic scheme (as definite, the probe on position of probe specification and number, select liquid working substance, determine injected dose etc.) earlier according to tumor size and the position determined by image documentation equipment (as B ultrasonic, CT, nuclear magnetic resonance, NMR etc.);
2. patient's corresponding site is implemented anesthesia;
3. will inject probe inserts in the tissue of target area according to therapeutic scheme and under the guiding of image documentation equipment;
4. according to needed amount of heat, apply suitable heating power, temperature decision injection rate or adjustment heating power by monitoring the bringing-up section liquid working substance in real time in the injection process;
5. monitor the temperature-responsive of target area tissue closely, according to circumstances finish or continue treatment.
The active injection thermotherapy probe that is used for neoplasm targeted therapy of the present utility model, can directedly also will send into the tumor target area through heated liquid working medium rapidly, release energy rapidly, do not need water cooling, absolute Wicresoft, applicable to the oncotherapy of any degree of depth, and can be used in combination with other oncotherapy mode (as chemotherapy, radiotherapy etc.) easily.
Description of drawings
Fig. 1 is a structural representation of the present utility model;
Fig. 2 is the structural representation of needle body part 10;
Fig. 3 is the structural representation that has the needle tubing part 20 of heating element heater;
Fig. 4 is the A-A cutaway view that has the needle tubing part 20 of heating element heater;
Fig. 5 is the B-B cutaway view that has the needle tubing part 20 of heating element heater;
Fig. 6 is the C-C cutaway view that has the needle tubing part 20 of heating element heater.
The specific embodiment
Further describe this utility model below in conjunction with the drawings and specific embodiments:
Fig. 1 is a structural representation of the present utility model; Fig. 2 is the structural representation of needle body part 10; Fig. 3 is the structural representation of band needle tubing part 20; Fig. 4 is the A-A cutaway view of needle tubing part 20; Fig. 5 is the B-B cutaway view of needle tubing part 20; Fig. 6 is the C-C cutaway view of needle tubing part 20; As seen from the figure, the active injection thermotherapy probe that is used for neoplasm targeted therapy that this utility model provides comprises needle body part 10 and needle tubing part 20; Described needle tubing part 20 is for having the needle tubing part of heating element heater;
Described needle body part 10 comprises:
One cylinder barrel shaped cavity 1; Be installed on needle tubing mouthpiece 2 on described cylinder barrel shaped cavity 1 blind end and intracavity inter-connection described cylinder barrel shaped cavity 1; And with the into a single integrated structure flange 5 of the opening end of described cylinder barrel shaped cavity 1;
One piston type is propelled bar 3; Described piston type is propelled bar 3 and is comprised: be installed on the piston crown 31 in described cylinder barrel shaped cavity 1 inner chamber slidably; Have a graduated bar bar portion 32 that propels with piston crown 31 fuses; And be connected in the shank 33 of propelling bar bar portion 32 ends; And the cavity 4 that forms between described cylinder barrel shaped cavity 1 inner chamber and the described piston crown 31 in order to carrying liquid working medium;
Described needle tubing part 20 comprises:
Interior pipe 7 and the outer tube 6 placed with one heart, the length of pipe 7 is less than described outer tube 6 in described, pipe 7 is fixed by welding in the top with outer tube 6 in described, in pipe 7 also be fixed together with outer tube 6 in the lower end by welding, described outer tube 6 lower ends are the point that has tapering, and the preceding intrasegmental part of described outer tube 6 leaves heating chamber 9;
Filling in described, manage 7 and outer tube 6 between annulus 67 in implant;
Pipe 7 upper ends are connected with the needle tubing mouthpiece 2 of described needle body part 10 in described; Also comprise
Be placed on heating element heater and thermocouple in the heating chamber 9 of described needle tubing part 20; The annulus 67 that the lead-in wire 8 of described heating element heater and thermocouple passes between described interior pipe 7 and the outer tube 6 is drawn from needle tubing part 11 upper ends.
Described piston crown 31 is a hollow circular cylinder.Described cylinder barrel shaped cavity 1, interior pipe 7 and outer tube 6 are stainless steel part.Described cavity 4 is the cavity in order to splendid attire water, saline, ethanol, dehydrated alcohol, acetum, hydrochloric acid solution or sulfuric acid solution liquid working substance.Described cavity 4 is for containing the cavity of treatment tumor with the liquid working substance of chemotherapy medicinal liquid in order to splendid attire.Described piston type is propelled the propel bar of bar 3 for glass material.The described heating element heater that is placed in the heating chamber 9 is electric heating device, radio-frequency antenna or the laser fiber that carries external power supply.
Embodiment
Each position of present embodiment is all adopted cylindrical.Wherein have in the cylinder barrel shaped inner chamber 1 and be loaded with liquid working substance, the needle tubing mouthpiece 2 that links to each other with the blind end of cylinder barrel shaped inner chamber 1 communicates with cylinder barrel shaped inner chamber 1 inner chamber; Needle tubing mouthpiece 2 ends have external screw thread, and there is female thread interior pipe 7 ends, by internal and external screw thread needle tubing mouthpiece 2 closely is connected with interior pipe 7, so propel at piston type under the effect of propelling of bar 3, liquid working substance in the cylinder barrel shaped inner chamber 1 is just injected by needle tubing mouthpiece 2 places, flow in the heating chamber 9 of described needle tubing part 20 along interior pipe 7 afterwards, under the heating of heating element heater, after raising rapidly, the temperature of liquid working substance annotated in the tissue of human tumor target area from the most advanced and sophisticated exit of described needle tubing part 20.In the injection process, monitor too high or too low for temperature with the liquid working substance that prevents to be injected into tumor tissues to the temperature of the liquid working substance in the heating chamber 9 in real time.
The structure of needle body part 10 as shown in Figure 2, cylinder barrel shaped inner chamber 1 and needle tubing mouthpiece 2 are made by rustless steel; Also can be together between needle tubing mouthpiece 2 and the cylinder barrel shaped inner chamber 1 by welded seal.The wall thickness of cylinder barrel shaped inner chamber 1 can be between the 0.1-2mm, and the intracavity diameter of cylinder barrel shaped inner chamber 1 can be at 5mm between the 50mm, and the length of cylinder barrel shaped inner chamber 1 can be between 20mm to 300mm; The internal diameter of needle tubing mouthpiece 2 can be 0.5mm between the 5mm, and wall thickness can be 1mm-5mm.The external diameter that piston type is propelled bar 3 is designed to and can closely slides on the inwall of cylinder barrel shaped inner chamber 1, the liquid working substance of the cavity 4 of cylinder barrel shaped (cavity 4 in order to carrying liquid working medium that forms between cylinder barrel shaped cavity 1 inner chamber and the piston crown 31) can be propelled away thus, and avoid liquid working substance to ooze out simultaneously from the slit that cylinder barrel shaped inner chamber 1 and piston type are propelled between the bar 3.Piston type is propelled bar 3 and can be fired into by glass, is weight reduction, and the piston crown 31 that piston type is propelled bar 3 can be made into hollow structure; Propel and be carved with the volume scale on the bar 32, the liquid working substance dosage that injects in order to tolerance; Piston type is propelled bar 3 external diameters and be can be 5mm between the 50mm, and length is then determined according to the inner chamber height of cylinder barrel shaped inner chamber 1, be can be between the 20mm to 300mm.
Needle tubing part 20 (as shown in Figure 3) is made up of outer tube 6 and interior pipe 7, and the inner and outer pipes wall thickness can be 0.1mm-1mm, and length can be 15mm～350mm, makes by rustless steel, and interior pipe 7 is than outer tube 6 short 5mm-20mm; In pipe 7 be the hollow type tubule, and the upper end is gradually-reducing shape, tapered portion length is 2mm-20mm, internal diameter is 1mm-20mm, interior pipe 7 bottoms are isodiametric elongated tubular, and internal diameter is 0.1mm-2mm; Outer tube 6 is concentric with interior pipe 7, and the former is wrapped in inside with the latter, and the circular cylindrical space between the two is used to arrange the lead-in wire 8 of heating element heater and thermocouple, and fills up with implant.Outer tube 6 is fixed by welding in the upper end with interior pipe 7, and the lead-in wire 8 of heating element heater and thermocouple is from wherein drawing; In pipe 7 also be fixed together with outer tube 6 in the lower end by welding, the lead-in wire 8 of heating element heater and thermocouple leads to the inner chamber 9 (bringing-up section) of needle tubing lower end herein.The upper end of outer tube 6 also is gradually-reducing shape, and tapered portion length is 2mm-30mm, and internal diameter is 3mm-30mm, and the bottom of outer tube 6 is isodiametric fine long tube, and internal diameter is 0.5mm-5mm.The machine of needle tubing is if can be provided with the temperature of thermocouple with tumor tissues in the monitor therapy process in strong 9.
Heating element heater and needle tubing partly adopt integrated design (as shown in Figure 3), and the dispensing end of needle tubing has the heating chamber 9 that length is 5mm-20mm, and heating chamber 9 has only one deck outer tube, is furnished with heating element heater and thermocouple 10 in the heating chamber 9.Liquid working substance in the cylinder barrel shaped inner chamber 1 in needle tubing, manage 7 be injected to the needle tubing bringing-up section after, heating element heater heats it, treats that temperature is increased to rapidly after the treatment temperature by notes people target area tissue.
Because this utility model adopts active injection probe, heating liquid working medium is finished in area for treatment, so its hot targeting is good, can not insert along the health tissues of journey probe in the therapeutic process and cause any hot injury.Heater means of the present utility model can have a variety of, can adopt the electrothermal device heating, also can adopt radio frequency, laser etc.The liquid working substance that this utility model can adopt also has many types, as water, saline, ethanol, dehydrated alcohol, acetum, hydrochloric acid solution and sulfuric acid solution etc., and can add some chemotherapeutics in these liquid working substance kinds, implement the therapeutic alliance of thermotherapy and chemotherapy simultaneously, certainly will increase therapeutic effect greatly like this.Thermotherapy probe external diameter minimum of the present utility model can be accomplished below the 2mm, can implement the percutaneous puncture operation easily for deep tumor, operation wound is little, and can adopt multiprobe to implement real shape treatment by the treatment plan of precision for the irregular big tumor of the pole of figure.This utility model can also apply certain electric field to area for treatment very easily simultaneously, to strengthen the sensitivity of tumor cell to thermotherapy.In addition, the active injection thermotherapy that this utility model provides be except can implementing the therapeutic alliance with chemotherapy, can also be easily and other therapeutic modality (as radiotherapy etc.) Joint Implementation.
Comprehensive above-mentioned these factors, the active injection thermotherapy probe that the utility model proposes is not only with low cost, and can reach good thermotherapy effect, therefore compares existing heat treatment unit, will have very strong competitiveness.
Claims (7)
1, a kind of active injection thermotherapy probe that is used for neoplasm targeted therapy comprises needle body part (10) and needle tubing part (20); It is characterized in that described needle tubing part (20) is for having the needle tubing part of heating element heater;
Described needle body part (10) comprising:
One cylinder barrel shaped cavity (1); Be installed on needle tubing mouthpiece (2) on described cylinder barrel shaped cavity (1) blind end and intracavity inter-connection described cylinder barrel shaped cavity (1); And with the into a single integrated structure flange (5) of the opening end of described cylinder barrel shaped cavity (1);
One piston type is propelled bar (3); Described piston type is propelled bar (3) and being comprised: be installed on the piston crown (31) in described cylinder barrel shaped cavity (1) inner chamber slidably; Have a graduated bar bar portion (32) that propels with piston crown (31) fuses; And be connected in the shank (33) of propelling bar bar portion (32) end; And the cavity in order to carrying liquid working medium (4) that forms between described cylinder barrel shaped cavity (1) inner chamber and the described piston crown (31);
Described needle tubing part (20) comprising:
Concentric interior pipe of placing (7) and outer tube (6), the length of pipe (7) is less than described outer tube (6) in described, pipe (7) is fixed by welding in the top with outer tube (6) in described, interior pipe (7) also is fixed together by welding and outer tube (6) in the lower end, described outer tube (6) lower end is the point that has tapering, and the preceding intrasegmental part of described outer tube (6) leaves heating chamber (9);
The implant in the annulus (67) between (7) and the outer tube (6) is managed in filling in described;
Pipe (7) upper end is connected with the needle tubing mouthpiece (2) of described needle body part (10) in described; Also comprise
Be placed on heating element heater and thermocouple in the heating chamber (9) of described needle tubing part (20); The annulus (67) that the lead-in wire of described heating element heater and thermocouple (8) passes between described interior pipe (7) and the outer tube (6) is drawn from needle tubing part (11) upper end.
2, by the described active injection thermotherapy probe that is used for neoplasm targeted therapy of claim 1, it is characterized in that described piston crown (31) is a hollow circular cylinder.
3, by the described active injection thermotherapy probe that is used for neoplasm targeted therapy of claim 1, it is characterized in that described cylinder barrel shaped cavity (1), interior pipe (7) and outer tube (6) are stainless steel part.
4, by the described active injection thermotherapy probe that is used for neoplasm targeted therapy of claim 1, it is characterized in that described cavity (4) is the cavity in order to splendid attire water, saline, ethanol, dehydrated alcohol, acetum, hydrochloric acid solution or sulfuric acid solution liquid working substance.
By claim 1 or the 4 described active injection thermotherapy probes that are used for neoplasm targeted therapy, it is characterized in that 5, described cavity (4) is for containing the cavity of treatment tumor with the liquid working substance of chemotherapy medicinal liquid in order to splendid attire.
6. by the described active injection thermotherapy probe that is used for neoplasm targeted therapy of claim 1, it is characterized in that described piston type is propelled the propel bar of bar (3) for glass material.
8. by the described active injection thermotherapy probe that is used for neoplasm targeted therapy of claim 1, it is characterized in that the described heating element heater that is placed in the heating chamber (9) is electric heating device, radio-frequency antenna or the laser fiber that carries external power supply.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620116204 CN200957108Y (en) | 2006-05-26 | 2006-05-26 | Active injection type thermotherapy probe for tumor targeted therapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620116204 CN200957108Y (en) | 2006-05-26 | 2006-05-26 | Active injection type thermotherapy probe for tumor targeted therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN200957108Y true CN200957108Y (en) | 2007-10-10 |
Family
ID=38783982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200620116204 Expired - Lifetime CN200957108Y (en) | 2006-05-26 | 2006-05-26 | Active injection type thermotherapy probe for tumor targeted therapy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN200957108Y (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103281815A (en) * | 2013-06-07 | 2013-09-04 | 天津力神电池股份有限公司 | Constant-temperature heating stylus |
| US20160270418A1 (en) * | 2015-03-17 | 2016-09-22 | California Extraction Ventures, Inc. | Pressure gradient profiling in an extraction column |
| CN108056815A (en) * | 2017-12-28 | 2018-05-22 | 山东省立医院 | A kind of tumor microwave ablation needle with temperature controlling function |
| CN109730764A (en) * | 2018-12-28 | 2019-05-10 | 颜景臣 | A kind of tumor insertion thermotherapy instrument |
-
2006
- 2006-05-26 CN CN 200620116204 patent/CN200957108Y/en not_active Expired - Lifetime
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103281815A (en) * | 2013-06-07 | 2013-09-04 | 天津力神电池股份有限公司 | Constant-temperature heating stylus |
| US20160270418A1 (en) * | 2015-03-17 | 2016-09-22 | California Extraction Ventures, Inc. | Pressure gradient profiling in an extraction column |
| CN108056815A (en) * | 2017-12-28 | 2018-05-22 | 山东省立医院 | A kind of tumor microwave ablation needle with temperature controlling function |
| CN109730764A (en) * | 2018-12-28 | 2019-05-10 | 颜景臣 | A kind of tumor insertion thermotherapy instrument |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20071010 |
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| EXPY | Termination of patent right or utility model |