CN1971341B - Method for manufacturing contact lens capable of correcting high-order aberration of human eyes - Google Patents
Method for manufacturing contact lens capable of correcting high-order aberration of human eyes Download PDFInfo
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- CN1971341B CN1971341B CN2006101650835A CN200610165083A CN1971341B CN 1971341 B CN1971341 B CN 1971341B CN 2006101650835 A CN2006101650835 A CN 2006101650835A CN 200610165083 A CN200610165083 A CN 200610165083A CN 1971341 B CN1971341 B CN 1971341B
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- 238000012937 correction Methods 0.000 claims abstract description 18
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- 230000003287 optical effect Effects 0.000 claims description 30
- 230000000694 effects Effects 0.000 claims description 14
- 230000004438 eyesight Effects 0.000 claims description 9
- 239000010410 layer Substances 0.000 claims description 7
- 239000012780 transparent material Substances 0.000 claims description 4
- 230000015572 biosynthetic process Effects 0.000 claims description 3
- 238000005259 measurement Methods 0.000 claims description 3
- 230000001915 proofreading effect Effects 0.000 claims description 3
- 239000002356 single layer Substances 0.000 claims description 3
- 238000010276 construction Methods 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims 1
- 210000004087 cornea Anatomy 0.000 abstract description 10
- 238000012545 processing Methods 0.000 abstract description 2
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- 239000011521 glass Substances 0.000 abstract 1
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- 238000011835 investigation Methods 0.000 description 1
- 238000000608 laser ablation Methods 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
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- 230000009022 nonlinear effect Effects 0.000 description 1
- 238000001259 photo etching Methods 0.000 description 1
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Abstract
The invention discloses a contact lens capable of correcting high-order aberration of human eyes and a manufacturing method thereof. The glasses are provided or prepared with phase microstructures or microstructure elements capable of correcting higher-order aberration of human eyes in the lenses, and the manufacturing method comprises the following steps: measuring aberration data of the human eye; calculating the three-dimensional refractive index distribution in the lens capable of correcting the higher-order aberration of the human eyes according to the aberration data and the diopter correction capability of the original lens; and processing the required three-dimensional refractive index distribution in the contact lens material by utilizing the focused ultrashort pulse laser beam. Compared with the prior art, the phase microstructure capable of correcting the higher-order aberration of the human eye is arranged or prepared in the lens, and the surface of the lens is still smooth, so that the cornea of the human eye is not stimulated, the wearing comfort is not influenced, and the cornea of the human eye is not damaged. In addition, the phase microstructure is arranged or prepared in the lens, so that the reduction or loss of the correction capability caused by pollution or abrasion of the phase microstructure is avoided.
Description
Technical field
The present invention relates to a kind of contact lenses, relate in particular to a kind of contact lenses that can proofread and correct the human eye higher order aberratons.The invention still further relates to the method for making of the contact lenses that can proofread and correct the human eye higher order aberratons.
Background technology
The decline of human eyesight has a strong impact on a people's normal life, therefore must correct.Traditional vision correction is mainly by wearing frame eyeglasses or contact lenses, perhaps realize by operative treatment, rectification mainly be low order aberrations such as out of focus, astigmatism.In recent years, the fast development of wavefront sensing technology makes the accurate measurement of human eye higher order aberratons become a reality, and also makes the correction of human eye higher order aberratons become possibility simultaneously.The people such as Junzhong doctor Liang of David doctor Williams of U.S. Rochester university and German Heidelberg university think that the correction of higher order aberratons has vital role to improving the human eye vision effect after further investigation.In recent years, the human eye higher order aberratons bearing calibration of proposition mainly contains cornea laser and corrects (laserablation of cornea or wavefront guided LASIK), the rectification of implanted internal oculoscope (intraocular lens), contact lens correction, phase-plate rectification (phase plate) etc.These methods respectively have relative merits.Cornea laser is corrected and implanted internal oculoscope technology is therapeutic method of surgery, has higher risk; Phase-plate (frame eyeglasses) then moves very responsive to the position, the actual rectification effect that uses is difficult to guarantee.Comparatively speaking, contact lenses are than operative treatment safety, and the position is moved also not as phase-plate (frame eyeglasses) sensitivity, therefore have more wide use prospect.
Aspect the making of contact lenses, traditional mechanical means can't be produced the contact lenses that can proofread and correct the human eye higher order aberratons." human eye correction for higher order aberrations method " (Chinese patent application numbers 200410009115.3, publication number CN1702494A, open day on November 30th, 2005) by adopting photoetching process the phase place microstructure is inscribed in the correction that the human eye higher order aberratons is realized on the contact lens material surface.The phase place microstructure that U.S. Patent application " artificial eye scope method for making " (Method for producing anartificial ocular lense, publication number US2002/0154271 A1) uses laser beam directly to go out to proofread and correct the human eye higher order aberratons in the contact lens material surface working.The shortcoming of above-mentioned two kinds of method for makings is that microstructure is positioned at the contact lens surface, both may stimulate the eyes cornea, influences the comfortable wearing degree, even meeting harmed eye cornea; In addition, microstructure is positioned at the contact lens surface and also may loses the higher order aberratons calibration function because of factors such as surface contamination or friction wears.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of contact lenses that can proofread and correct the human eye higher order aberratons, and these contact lenses can not stimulate the eyes cornea, also can the higher order aberratons calibration function be reduced or inefficacy because of factors such as surface contamination or friction wears.Another technical matters that the present invention will solve provides the above-mentioned method for making that can proofread and correct the contact lenses of human eye higher order aberratons.
The technical solution adopted for the present invention to solve the technical problems is: can proofread and correct the contact lenses of human eye higher order aberratons, comprise eyeglass, described inner of eyeglasses has the phase place microstructure that can proofread and correct the human eye higher order aberratons.
The single-layer and transparent material of the material of described eyeglass for having nonlinear optical effect (two-photon polymerized effect or other nonlinear effect).
Described eyeglass also can be sandwich construction, and wherein a certain at least middle layer is the transparent material with nonlinear optical effect.
Can proofread and correct the method for making of the contact lenses of human eye higher order aberratons, may further comprise the steps:
(1) measure human eye aberration data W (x, y);
(2) the diopter calibration capability according to human eye aberration data and the original eyeglass of contact lenses calculates the inner certain interior three-dimensional refractive index distribution n in zone of the contact lens that can proofread and correct the human eye higher order aberratons
0(x, y, z);
(3) use the inner certain zone of focusing ultra-short pulse laser bundle irradiation contact lens material, two-photon polymerized effect or other nonlinear optical effect by contact lens material change the three-dimensional refractive index distribution n (x that is focused ultra-short pulse laser bundle irradiation area in the contact lens material, y, z), the index distribution n that itself and step (2) are calculated
0(x, y z) equate: and n (x, y, z)=n
0(x, y, z).
Adopt in the described step (1) based on the human eye aberration surveying instrument of Hartmann wave front sensor and measure human eye aberration.
Mathematical formulae is passed through in the calculating that three-dimensional refractive index distributes in the described step (2)
Realize,
Wherein (x is illustrated in y) that (x, y) the coordinate place has the contact lens material thickness of nonlinear optical effect to L.
The original eyeglass of contact lenses in described step (2) and (3) is the eyeglass of not diopters of correction aberration or the eyeglass of diopters of correction aberration.
The pulse width range of the ultra-short pulse laser bundle in the described step (3) is 10
-15Second (1 femtosecond)-10
-9Between second (1 nanosecond).
Ultra-short pulse laser Shu Youyi lens focus in the described step (3) is in contact lens, and the focal position is positioned at the contact lens material with nonlinear optical effect.
The formation that three-dimensional refractive index in the described step (3) distributes realizes by two-photon polymerized effect or other nonlinear optical effect of contact lens material.
3-D scanning contact lenses position or focussed laser beam focal position or the relative position of focussed laser beam focus in contact lens are passed through in the formation that three-dimensional refractive index in the described step (3) distributes, and control the laser beam power and the irradiation time realization at each scanning position place.
After finishing described step (3), can revise, until obtaining satisfied vision correction effect by actual vision correction effect repeating step (1)～(3).
Principle of the present invention is: the material with nonlinear optical effect that contact lenses use is under the irradiation that focuses on the ultra-short pulse laser bundle, when the laser beam power density that focuses on ultra-short pulse laser bundle focal position near zone meets or exceeds certain value, lens materials in this zone is because of two-photon polymerized effect or other nonlinear optical effect generation refraction index changing, thereby changed the optical phase in should the zone.Because factors such as the power density of the nonlinear optical properties of the refraction index changing amount of a certain position and material, this position laser beam and irradiation time are relevant in the material, by 3-D scanning focussed laser beam focus in contact lenses relative position and control the laser beam irradiation power and the irradiation time at each scanning position place, can distribute in the inner three-dimensional refractive index that forms of contact lens material with given shape.When the three-dimensional refractive index distribution that forms when contact lens material is inner is complementary with the human eye aberration data of measuring, can reach the purpose of proofreading and correct the human eye higher order aberratons.
The present invention compared with prior art, the phase place microstructure (perhaps claiming micro-structured component) that can proofread and correct the human eye higher order aberratons is arranged on the inside of contact lens, and the surface of eyeglass remains smooth, therefore can not cause stimulation to the eye cornea, can not influence the comfortable wearing degree, can not cause damage certainly yet cornea.In addition, the phase place microstructure is arranged on inner of eyeglasses and has avoided also that contaminated or wearing and tearing reduce or lose calibration capability because of the phase place microstructure.
Description of drawings
The present invention is further described below in conjunction with drawings and Examples.
Fig. 1 is the synoptic diagram of the embodiment of a kind of individual layer lens structure of the contact lenses that can proofread and correct the human eye higher order aberratons of the present invention;
Fig. 2 is the synoptic diagram of the embodiment of a kind of many layer mirror chip architecture that can proofread and correct the contact lenses of human eye higher order aberratons of the present invention (being three-decker herein);
Fig. 3 is the synoptic diagram of the embodiment that makes the used device of the contact lenses that can proofread and correct the human eye higher order aberratons of the present invention.
Embodiment
As shown in Figure 1, the eyeglass 2 of contact lenses is a single layer structure, and the material of this eyeglass 2 is the material (being generally macromolecular material) with nonlinear optical effect, is provided with the phase place microstructure 1 that can proofread and correct the human eye higher order aberratons in the inside of contact lens 2.
As shown in Figure 2, the eyeglass of these contact lenses is a three-decker, and the material in its middle layer 3 is the material (being generally macromolecular material) with nonlinear optical effect, and the upper and lower can be other contact lens materials that does not have nonlinear optical effect.3 inside is provided with the phase place microstructure 1 that can proofread and correct the human eye higher order aberratons in the middle layer.Certainly, the eyeglass of contact lenses also can be more multi-layered structure, as long as a middle layer is wherein arranged is the material with nonlinear optical effect, the phase place microstructure 1 that can proofread and correct the human eye higher order aberratons gets final product with regard to being arranged on this middle level of being made by the material with nonlinear optical effect.
A kind of device that is used to make the contact lenses that can proofread and correct the human eye higher order aberratons is formed as shown in Figure 3, and it comprises ultra-short pulse laser light source 4, high speed optical shutter 5, variable power attenuator 6, beam steering catoptron 7, condenser lens 8, automatically controlled three-dimensional objective table 10, computing machine 11 and human eye aberration measuring instrument 12.Wherein, human eye aberration measuring instrument 12 links to each other with computing machine 11, and the human eye aberration data that human eye aberration measuring instrument 12 is measured can be sent into computing machine 11; High speed optical shutter 5 links to each other with computing machine 11 respectively with variable power attenuator 6, can be controlled by computing machine 11.
The step of utilizing this device to make the contact lenses that can proofread and correct the human eye higher order aberratons is:
(1) (x y) accurately measures, and measurement result is imported computing machine 11, this human eye aberration measuring instrument 12 general human eye aberration surveying instruments that adopt based on Hartmann wave front sensor to utilize the aberration W of 12 pairs of human eyes of human eye aberration measuring instrument;
(2) distributed according to the three-dimensional refractive index that the diopter calibration capability of human eye aberration data and the original eyeglass of contact lenses calculates in the inner certain zone of the contact lens that can proofread and correct the human eye higher order aberratons by computing machine, mathematical formulae is passed through in the calculating of this index distribution
Realize that (x is illustrated in y) that (x, y) the coordinate place has the contact lens material thickness of nonlinear optical effect to L here.(x, y) interior and coordinate z has nothing to do, thereby obtains Δ n at certain thickness L can to make the contact lens inner refractive index in actual fabrication process
0(x, y)=W (x, y)/L (x, y);
(3) eyeglass to be processed 9 is placed on the automatically controlled three-dimensional objective table 10, the output beam 13 of ultra-short pulse laser light source 4 focuses on the inside that is placed on contact lens 9 automatically controlled three-dimensional objective table 10 on by condenser lens 8 through high speed optical shutter 5 control irradiation times, variable power attenuator 6 control irradiation powers, beam steering catoptron 7 after changing direction, and the focal position is positioned at the contact lens material with nonlinear optical effect.Two-photon polymerized effect or other nonlinear optical effect by contact lens material change the refractive index that is focused ultra-short pulse laser bundle irradiation area in the contact lens material, and lens position is realized 3-D scanning by the position of three-dimensional moving stage 10, obtaining three-dimensional refractive index in contact lens material distributes, make it consistent, thereby reach the purpose of proofreading and correct the human eye higher order aberratons with index distribution that step (2) calculates.High speed optical shutter 5, variable power attenuator 6 and automatically controlled three-dimensional objective table 10 are by computing machine 11 controls; Control the position of laser focusing point by moving automatically controlled three-dimensional objective table 10 at contact lens 9.In actual mechanical process, three-dimensional refractive index distributes and can also and use the one dimension objective table to vertically move lens position and realize by two-dimension scanning laser bundle position.
In process, the original eyeglass of the contact lenses that used both can be the eyeglass of diopters of correction aberration not, also can be the eyeglass of diopters of correction aberration.By after the above-mentioned steps completion of processing, can repeat above-mentioned steps according to the vision correcting effect of reality and revise, until obtaining satisfied vision correcting effect.
Claims (5)
1. can proofread and correct the method for making of the contact lenses of human eye higher order aberratons, comprise eyeglass, it is characterized in that: described inner of eyeglasses has the phase place microstructure that can proofread and correct the human eye higher order aberratons; The material of described eyeglass is the single-layer and transparent material with nonlinear optical effect; Described eyeglass is a sandwich construction, and wherein at least one middle layer is the transparent material with nonlinear optical effect, and the step of making the described contact lenses that can proofread and correct the human eye higher order aberratons is as follows:
(1.1) preparation is used to make the device of the contact lenses that can proofread and correct the human eye higher order aberratons, it comprises ultra-short pulse laser light source (4), high speed optical shutter (5), variable power attenuator (6), beam steering catoptron (7), condenser lens (8), automatically controlled three-dimensional objective table (10), computing machine (11) and human eye aberration measuring instrument (12), wherein, human eye aberration measuring instrument (12) links to each other with computing machine (11), and the human eye aberration data that human eye aberration measuring instrument (12) is measured are sent into computing machine (11); High speed optical shutter (5) links to each other with computing machine (11) respectively with variable power attenuator (6), is controlled by computing machine (11);
(1.2) (x y) accurately measures, and measurement result is imported computing machine (11), and described human eye aberration measuring instrument (12) adopts the human eye aberration surveying instrument based on Hartmann wave front sensor to the aberration W of human eye to utilize human eye aberration measuring instrument (12);
(1.3) distributed according to the three-dimensional refractive index that the diopter calibration capability of human eye aberration data and the original eyeglass of contact lenses calculates in the inner certain zone of the contact lens that can proofread and correct the human eye higher order aberratons by computing machine (11), mathematical formulae is passed through in the calculating of this index distribution
Realize, here L (x, y) be illustrated in (x, y) the coordinate place has the contact lens material thickness of nonlinear optical effect, in actual fabrication process, can make the contact lens inner refractive index certain thickness L (x, irrelevant with coordinate z in y), thereby obtain Δ n
0(x, y)=W (x, y)/L (x, y);
(1.4) eyeglass to be processed (9) is placed on the automatically controlled three-dimensional objective table (10), the output beam (13) of ultra-short pulse laser light source (4) is through high speed optical shutter (5) control irradiation time, variable power attenuator (6) control irradiation power, focus on the inside of the contact lens (9) that is placed on the automatically controlled three-dimensional objective table (10) after beam steering catoptron (7) the change direction by condenser lens (8), the focal position is positioned at the contact lens material with nonlinear optical effect, two-photon polymerized effect by contact lens material changes the refractive index that is focused ultra-short pulse laser bundle irradiation area in the contact lens material, and lens position is realized 3-D scanning by the position of three-dimensional moving stage (10), obtaining three-dimensional refractive index in contact lens material distributes, make it consistent with index distribution that step (1.3) calculates, thereby reach the purpose of proofreading and correct the human eye higher order aberratons, high speed optical shutter (5), variable power attenuator (6) and automatically controlled three-dimensional objective table (10) are controlled by computing machine (11); Control the position of laser focusing point by moving automatically controlled three-dimensional objective table (10) in contact lens (9).
2. the method for making that can proofread and correct the contact lenses of human eye higher order aberratons according to claim 1 is characterized in that: the original eyeglass of described contact lenses is the eyeglass of diopters of correction aberration not or the eyeglass of diopters of correction aberration.
3. the method for making that can proofread and correct the contact lenses of human eye higher order aberratons according to claim 1 is characterized in that: the pulse width range of described ultra-short pulse laser bundle is 10
-15Second-10
-9Between second.
4. the method for making that can proofread and correct the contact lenses of human eye higher order aberratons according to claim 1, it is characterized in that: 3-D scanning contact lenses position or focussed laser beam focal position or the relative position of focussed laser beam focus in contact lens are passed through in the formation that described three-dimensional refractive index distributes, and control the laser beam power and the irradiation time realization at each scanning position place.
5. the method for making that can proofread and correct the contact lenses of human eye higher order aberratons according to claim 1, it is characterized in that: after finishing described step (1.4), vision correction effect repeating step (1.2)～(1.4) by reality are revised, until obtaining satisfied vision correction effect.
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| US20230157812A1 (en) * | 2017-02-10 | 2023-05-25 | University Of Rochester | Vision correction with laser refractive index changes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| BRPI0818693A8 (en) * | 2007-10-05 | 2018-08-14 | Essilor Int | METHOD FOR PROVIDING AN OPHTHALMIC LENS FOR EYECASTS BY CALCULATING OR SELECTING A DESIGN |
| KR101701767B1 (en) | 2009-09-01 | 2017-02-02 | 아르투어 브래들리 | Multifocal correction providing improved quality of vision |
| CN107065182A (en) * | 2017-03-08 | 2017-08-18 | 上海乐蜗信息科技有限公司 | A kind of virtual reality optical lens and virtual reality device |
| CN107272195A (en) * | 2017-07-27 | 2017-10-20 | 英诺激光科技股份有限公司 | A kind of method of utilization laser-adjusting optical system wavefront distribution |
| EP3667401A1 (en) * | 2018-12-12 | 2020-06-17 | Essilor International | Method and device for manufacturing an ophthalmic lens |
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| CN1702494A (en) * | 2004-05-24 | 2005-11-30 | 中国科学院光电技术研究所 | Method for correcting high-order aberration of human eyes |
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