CN1966050A - Medicament for treating heart disease and preparation process thereof - Google Patents

Abstract

Disclosed is a medicament for treating heart disease and its preparation, wherein the raw materials include liquidambar orientalis mill 0.3-2g, gum benzoin 0.3-2g, frankincense 3-12g, Loranthus mulberry mistletoe 10-18g, stem of mistletoe 10-30g, Ligusticum wallichii 3-15g, root of Chinese trichosannthes 10-15g, ginkgo leaves 5-12g, wild or spiny jujuba seed 1.5-5g, tuber fleeceflower stem 10-35g, red peony root 6-15g, root of red rooted saliva 3-12g, spicebush root 5-12g, giant knotweed rhizome 10-30g, wrinkled gianthyssop 5-10g, sandalwood 5-10g, borneol 0.03-0.1g, psoralea fruit 6-9g, cassia twig 3-12g, curcuma longa 3-10g, dalbergia wood 3-6g, prepared fleece-flower root 6-15g, astragalus root 10-20g, ilex pedunculosa 30-60g, prepared rhizome of rehmannia 15-30g, tetrandra root 5-12g, panicled swallowwort root 3-12g, notoginseng 3-12g, corydalis tuber 3-15g, curcuma root 5-15g, safflower 3-15g, achyranthes and cyathula root 6-30g, campanumaea pilosula 6-15g and dried wood-louse 10-30g.

Description

Cardiopathic medicine of a kind of treatment and preparation method

One, technical field: the present invention relates to treat heart disease Chinese medicine, cardiopathic medicine of especially a kind of treatment and preparation method.

Two, background technology: heart disease is varied, the coronary heart disease heart failure is arranged, heart gram anoxia, ischemia, blood supply insufficiency, atrial fibrillation, angina pectoris, the frequent premature beat of viral myocarditis sequela, rheumatic myocarditis, rheumatic heart disease, heart failure, pulmonary heart disease, sinus tachycardia or excessively slow atrial arrhythmia, nodal arrhythmia, qualitative arrhythmia, with diseases such as the insomnia shocks out of breath of fainting, the cardiopathic medicine of treatment also is varied at present, as Radix Salviae Miltiorrhizae Tabellae, brain heart health, pills for curing heart disease etc., these medicines all have certain curative effect for some heart diseases, certain mitigation can be played, but all heart disease can not be fundamentally treated.

Three, summary of the invention: the purpose of this invention is to provide cardiopathic medicine of a kind of treatment and preparation method, it has overcome the shortcoming of other medicines, the object of the present invention is achieved like this, it is by Styrax 0.3-2g, Benzoinum 0.3-2g, Olibanum 3-12g, Herba Taxilli 10-1g, Herba Visci 10-30g, Rhizoma Chuanxiong 3-15g, Radix Trichosanthis 10-15g, Folium Ginkgo 5-12g, Semen Ziziphi Spinosae 1.5-5g, Caulis Polygoni Multiflori 10-35g, Radix Paeoniae Rubra 6-15g, Radix Salviae Miltiorrhizae 3-12g, Radix Linderae 5-12g, Rhizoma Polygoni Cuspidati 10-30g, Herba Pogostemonis 5-10g, Lignum Santali Albi 5-10g, Borneolum Syntheticum 0.03-0.1g, Fructus Psoraleae 6-9g, Ramulus Cinnamomi 3-12g, Rhizoma Curcumae Longae 3-10g, Lignum Dalbergiae Odoriferae 3-6g, Radix Polygoni Multiflori Preparata 6-15g, Radix Astragali 10-20g, Radix Ilicis Pubescentis 30-60g, Radix Rehmanniae Preparata 15-30g, Radix Stephaniae Tetrandrae 5-12g, Radix Cynanchi Paniculati 3-12g, Radix Notoginseng 3-12g, Rhizoma Corydalis 3-15g, Radix Curcumae 5-15g, Flos Carthami 3-15g, Radix Achyranthis Bidentatae 6-30g, Radix Codonopsis 6-15g, Carapax et Plastrum Testudinis 10-30g makes, its preparation method is, the first step is concocted individual drug, Olibanum is fried, the Semen Ziziphi Spinosae parching to brown, Carapax et Plastrum Testudinis is used earlier the sandy soil parching to brown, reuse vinegar swashs crisp, Radix Achyranthis Bidentatae steeps with yellow wine earlier, oven dry again, Radix Codonopsis is earlier with yellow wine bubble, parching to brown again; Second step leached medicinal residues with above medicine crushing screening and gets final product; The 3rd step got final product according to some is encapsulated.

Pharmacology analysis: Styrax has the refreshment of having one's ideas straightened out and wards off the turbid effect of dirtyization, and the treatment soldier property sent out ambition abdominal part is pain completely, coronary disease angina pectoris etc.; Benzoinum has the refreshment of having one's ideas straightened out, promoting blood circulation and stopping pain, warm in nature, coma, gnathospasma, the trusted subordinate's pain of bursting, angina pectoris; Olibanum acrid in the mouth hardship, warm in nature, return liver heart spleen channel, have the effect of blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain, detumescence and promoting granulation, control trusted subordinate's stasis of blood pain, also can reduce liver abdomen cholesterol and synthesize and the performance effect for reducing fat; Herba Taxilli, bitter in the mouth is flat, has the strong muscle nourishing blood and preventing abortion effect of dispeling the wind, and the cholesterol sclerosis of blood vessels is had good efficacy, controls angina pectoris etc.; Herba Visci, bitter in the mouth is flat, flat invigorating the liver and kidney, bone and muscle strengthening, flat blood pressure, nourishing blood and preventing abortion, essential hypertension, in angina pectoris, the ARR treatment with curative effect the best of paroxysmal atrial fibrillation and ventricular premature contraction, Rhizoma Chuanxiong, the acrid in the mouth temperature is returned liver and gall pericardium channel, there is the promoting flow of QI and blood blood stasis dispelling to stimulate the menstrual flow to loose the wind analgesic effect, can expands heart coronary artery, coronary blood flow increasing, reduce myocardial oxygen consumption, resist myocardial ischemia etc., but also antithrombotic forms, improve cerebral circulation, cerebral ischemia is had protective effect; Radix Trichosanthis, sweet and slightly bitter taste, cold nature, blood fat reducing, preventing arteriosclerosis promotes the cell growth, prevents anemia, and radioprotective can improve immunologic function, can prevent myocardial infarction, and heart tonifying is enriched blood; The little bitterness of Folium Ginkgo is flat, and promoting blood circulation and stopping pain reduces blood and asks cholesterol, and coronary artery dilator, hypertension, coronary arteriosclerotic angina pectoris blood are asked hypercholesterolemia; Semen Ziziphi Spinosae, sweet in the mouth is flat, and the GUIXIN Liver Channel has the effect of tranquilizing by nourishing the heart arresting sweating tonifying YIN, also can resist frightened blood pressure lowering analgesia; Caulis Polygoni Multiflori has tranquilizing by nourishing the heart, nourishing blood to expel wind effect, and vexed uneasiness, the empty hyperhidrosis of body are had the higher effect of nourishing blood, and is excellent to coronary heart disease illness institute induced insomnia curative effect; Radix Paeoniae Rubra, the bitter in the mouth cold nature, blood circulation promoting and blood stasis dispelling, clearing away heat and cooling blood, expansible blood vessel wall, coronary blood flow increasing improves myocardial oxygen delivery, suppresses platelet aggregation, and the stronger thrombotic time of prolongation specificity is arranged, and resists myocardial ischemia etc.; Radix Salviae Miltiorrhizae acrid in the mouth cold nature blood circulation promoting and blood stasis dispelling, removing heat from blood eliminating carbuncle nourishing blood to tranquillize the mind, warm febrile disease nutrient blood has decreased heart rate and brings high blood pressure down, and increases heart hat blood flow volume, and blood fat reducing has protective effect etc. to hepatic injury; Radix Linderae acrid in the mouth is warm in nature; The Rhizoma Polygoni Cuspidati bitter in the mouth is cold in nature, has blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing dampness removing jaundice eliminating, blood pressure lowering, blood fat reducing, anticoagulant antiviral etc.; Herba Pogostemonis, the acrid in the mouth slightly warm in nature is returned taste and lung meridian, has removing dampness by means of aromatics and delivers expelling summer-heat, and middle gas is not transported, and heaviness sensation over the head and body can promote gastric secretion to the multiple pathogenic fungus leptospira of sick antibacterial, strengthens eupepsy, expansion blood capillary etc.; Lignum Santali Albi has promoting the circulation of QI to relieve pain, regulating qi-flowing for harmonizing stomach effect, to stomach spasm pain due to the illness such as coronary heart disease, angina pectoris and gastritis, gastric ulcer etc.; Borneolum Syntheticum acrid in the mouth bitterness is slightly cold, and GUIXIN spleen lung meridian has the refreshment of having one's ideas straightened out clearing away heat to alleviate pain, calentura coma, and the central nervous system is had excitation, promotes the division of neurogliocyte and the effect of growth etc. in addition; Fructus Psoraleae, it is warming spleen and stopping diarrha to have a kidney invigorating and YANG supporting, and sending down the abnormal ascending QI, strong muscle, soreness of waist and knee joint, hands and feet being not warm, muscle are unable etc.; Ramulus Cinnamomi has the detoxifcation cold expelling, diaphoresis expelling pathogenic factors from muscles, warming the meridian for promoting the flow of YANG QI effect, and to nervous breathing hard due to the heart, breast is coerced vexed pain, the limbs being moist and cold and dysuria, diseases such as anasarca; Rhizoma Curcumae Longae has the effect of removing blood stasis dissipating blood stasis promoting the circulation of QI to relieve pain, to trusted subordinate's feeling of fullness, pain in chest and hypochondrium etc. due to the illness such as coronary heart disease hepatitis; Lignum Dalbergiae Odoriferae has the removing blood stasis and activating blood flow analgesic therapy, to ward off dirtyization turbid, is had a pain etc. in the ambition due to coronary heart disease, the angina pectoris etc.; Radix Polygoni Multiflori Preparata, enrich and benefit essence and blood, the detoxifcation preventing the attack (or recurrence) of malaria, essence and blood loses empty, diseases such as consumption impairment of YIN blood; The Radix Astragali, sweet in the mouth is warm in nature, returns the spleen lung meridian, invigorating QI to consolidate the body surface resistance, hidroschesis granulation promotings etc. have cardiotonic to the heart of depletion, especially sink into depleted heart cardiotonic to imprisoning poisoning or fatigue, expansion peripheral blood vessel, coronary vasodilator, breast blood vessels etc. can be eliminated albuminuria again, the liver protecting, increase plasma protein, haemproteins and erythrocyte, antiviral etc.; Radix Ilicis Pubescentis has blood circulation and channel invigorating, and heat-clearing and toxic substances removing is to the pain in chest and hypochondrium due to the diseases such as angina pectoris hypertension, headache and dizzy, numb limbs and tense tendons etc.; Radix Rehmanniae Preparata has enriching yin and nourishing kidney, deficiency of YIN anemia, damage of essence, pain in the low back and legs; Radix Stephaniae Tetrandrae, the bitter in the mouth suffering is cold in nature, and have wind-damp dispelling and end splenalgia, arthralgia, joint stuffiness has coronary artery dilator, resists myocardial ischemia, arrhythmia, anti-pneumosilicosis, antiallergic, anti-relieving asthma etc.; The Radix Cynanchi Paniculati acrid in the mouth is warm in nature, has expelling wind and removing dampness, antalgesic-antipruritic, cardiac and abdominal pain dysmenorrhea, blood pressure lowering, blood fat reducing is arranged and prevent tremulous pulse sample induration, also has coronary blood flow increasing, improves myocardial metabolism, alleviate myocardial ischemia; Radix Notoginseng, sweet and slightly bitter taste, property wets and has removing stasis to stop bleeding, reducing swelling and alleviating pain, the energy coronary blood flow increasing, improve the supply of myocardium blood oxygen, decreased heart rate reduces myocardial oxygen consumption, improve the cardiac muscle circulation, thereby, bring high blood pressure down, and arrhythmia to coronary disease, dirty angina pectoris energy blood vessel dilating, shock, anti-liver injury etc.; Rhizoma Corydalis, the acrid in the mouth hardship, warm in nature, have blood-activating and qi-promoting, pain relieving is used for the breast splenic precordial pain, wrist abdomen pain, stagnation of liver-QI stagnates, and the Rhizoma Corydalis raised path between farm fields can increase the heart coronary flow, and myocardial necrosis is had certain protection effect, arrhythmia, blood fat reducing etc.; Radix Curcumae, the acrid in the mouth bitterness is cold, has promoting blood circulation and stopping pain promoting QI circulation for relieving depression, removing heat from the heart to restore the consciousness, promoting the function of the gallbladder to alleviate jaundice etc.; The Flos Carthami acrid in the mouth is warm in nature, has promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing, breast splenic precordial pain, excited heart, the effect of coronary blood flow increasing and myocardial nutrition blood flow, arrhythmia; The Radix Achyranthis Bidentatae bitter in the mouth is acid flat, has blood circulation promoting and blood stasis dispelling, liver and kidney tonifying, prolongs clotting time and of short duration hypotensive activity; Radix Codonopsis, sweet in the mouth is flat, has strengthening QI of middle-JIAO, an effect of nourishing blood of promoting the production of body fluid; Carapax et Plastrum Testudinis, sweet in the mouth is flat, has the effect of nourishing YIN for suppressing the hyperactive YANG, tonifying kidney and promoting digestion, tranquilizing by nourishing the heart.

Patient source: transfer 85 from polyclinic; Transfer 65 from professional outpatient service.

Efficacy analysis: be pressed into the group standard, treat 150 altogether, wherein the male is 105,45 of women; The former course of disease 85 of persons more than 5 years, 75 of persons below 5 years.

Treatment method: take medicine each 4 capsules every day 3 times.Be one-period January, can fully recover in three months.

Therapeutic outcome: warp is to 150 patient, and total effective rate reaches 98%, and cure rate reaches 90%.

Poplar Shi Balang village, Liu Tun town, Puyang County, Henan Province poplar becomes Kui to suffer from a heart complaint 15 years, seeks medical advice everywhere, controls bad disease, and after taking this medicine, effect is obvious, serve on 2 years, the disease recovery from illness; The cadre Gao Peng of Puyang County, Henan Province water conservancy bureau letter was suffered from arrhythmia 5 years, and it is invalid to cure the disease everywhere, since taking this medicine six months, does not commit excesses disease again; The burnt village Wang Xue in Liu Tun town, Puyang County, Henan Province has just violated the lung heart, the wind heart, coronary disease three-core heart disease for many years, takes this medicine a year and a half continuously, state of an illness recovery from illness.

Four, the specific embodiment: the present invention is by Styrax 0.3-2g, Benzoinum 0.3-2g, Olibanum 3-12g, Herba Taxilli 10-18g, Herba Visci 10-30g, Rhizoma Chuanxiong 3-15g, Radix Trichosanthis 10-15g, Folium Ginkgo 5-12g, Semen Ziziphi Spinosae 1.5-5g, Caulis Polygoni Multiflori 10-35g, Radix Paeoniae Rubra 6-15g, Radix Salviae Miltiorrhizae 3-12g, Radix Linderae 5-12g, Rhizoma Polygoni Cuspidati 10-30g, Herba Pogostemonis 5-10g, Lignum Santali Albi 5-10g, Borneolum Syntheticum 0.03-0.1g, Fructus Psoraleae 6-9g, Ramulus Cinnamomi 3-12g, Rhizoma Curcumae Longae 3-10g, Lignum Dalbergiae Odoriferae 3-6g, Radix Polygoni Multiflori Preparata 6-15g, Radix Astragali 10-20g, Radix Ilicis Pubescentis 30-60g, Radix Rehmanniae Preparata 15-30g, Radix Stephaniae Tetrandrae 5-12g, Radix Cynanchi Paniculati 3-12g, Radix Notoginseng 3-12g, Rhizoma Corydalis 3-15g, Radix Curcumae 5-15g, Flos Carthami 3-15, Radix Achyranthis Bidentatae 6-30g, Radix Codonopsis 6-15g, Carapax et Plastrum Testudinis 10-30g makes, its preparation method is, the first step is concocted individual drug, Olibanum is fried, the Semen Ziziphi Spinosae parching to brown, Carapax et Plastrum Testudinis is used earlier the sandy soil parching to brown, reuse vinegar swashs crisp, Radix Achyranthis Bidentatae steeps with yellow wine earlier, oven dry again, Radix Codonopsis is earlier with yellow wine bubble, parching to brown again; Second step leached medicinal residues with above medicine crushing screening and gets final product; The 3rd step got final product according to some is encapsulated.

Claims (2)

1, the cardiopathic medicine of a kind of treatment is characterized in that: it is by Styrax 0.3-2g, Benzoinum 0.3-2g, Olibanum 3-12g, Herba Taxilli 10-18g, Herba Visci 10-30g, Rhizoma Chuanxiong 3-15g, Radix Trichosanthis 10-15g, Folium Ginkgo 5-12g, Semen Ziziphi Spinosae 1.5-5g, Caulis Polygoni Multiflori 10-35g, Radix Paeoniae Rubra 6-15g, Radix Salviae Miltiorrhizae 3-12g, Radix Linderae 5-12g, Rhizoma Polygoni Cuspidati 10-30g, Herba Pogostemonis 5-10g, Lignum Santali Albi 5-10g, Borneolum Syntheticum 0.03-0.1g, Fructus Psoraleae 6-9g, Ramulus Cinnamomi 3-12g, Rhizoma Curcumae Longae 3-10g, Lignum Dalbergiae Odoriferae 3-6g, Radix Polygoni Multiflori Preparata 6-15g, Radix Astragali 10-20g, Radix Ilicis Pubescentis 30-60g, Radix Rehmanniae Preparata 15-30g, Radix Stephaniae Tetrandrae 5-12g, Radix Cynanchi Paniculati 3-12g, Radix Notoginseng 3-12g, Rhizoma Corydalis 3-15g, Radix Curcumae 5-15g, Flos Carthami 3-15g, Radix Achyranthis Bidentatae 6-30g, Radix Codonopsis 6-15g, Carapax et Plastrum Testudinis 10-30g makes.

2, the described a kind of preparation method for the treatment of cardiotropic formulation of claim 1, it is characterized in that: the first step is concocted individual drug, Olibanum is fried the Semen Ziziphi Spinosae parching to brown, Carapax et Plastrum Testudinis is used earlier the sandy soil parching to brown, and reuse vinegar swashs crisp, and Radix Achyranthis Bidentatae steeps with yellow wine earlier, oven dry again, Radix Codonopsis are earlier with yellow wine bubble, parching to brown again; Second step leached medicinal residues with above medicine crushing screening and gets final product; The 3rd step got final product according to some is encapsulated.