CN1958052B - Medication for treating rheumatoid arthritis, ankylosing spondylitis - Google Patents
Medication for treating rheumatoid arthritis, ankylosing spondylitis Download PDFInfo
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- CN1958052B CN1958052B CN200510096296A CN200510096296A CN1958052B CN 1958052 B CN1958052 B CN 1958052B CN 200510096296 A CN200510096296 A CN 200510096296A CN 200510096296 A CN200510096296 A CN 200510096296A CN 1958052 B CN1958052 B CN 1958052B
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Abstract
A Chinese medicine in the form of honeyed pill for treating rheumatoid arthritis and tonic rachitis is prepared from 15 Chinese-medicinal materials including ant, epimedium, ginseng, Chinese angelica root, etc.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of rheumatoid arthritis, ankylosing spondylitis, belong to the field of Chinese medicines.
Background technology
Rheumatoid arthritis is a kind of systemic autoimmune disease based on chronic polyarthritis.Main clinical manifestation is the arthralgia due to the little articular synovitis, and cartilage destruction, joint space narrow down then, and cause joint stiffness, deformity, dysfunction because of serious bone destruction, absorption late period.In addition, also can feel cold with weak, low grade fever, loss of appetite, brothers, anemia, general symptom such as become thin and rheumatoid subcutaneous nodule, vasculitis, cardiopulmonary portion pathological changes etc. show outside the joint.The prevalence of China's rheumatoid arthritis is 0.24%-0.5% according to investigations, and the whole nation has 5,000,000 patients approximately, and the women is more than the male, about 2-3: 1, any age all can fall ill, with 20-45 year serve as maximum.Ankylosing spondylitis is a kind of main infringement spinal column, and can involve the sacro-iliac joints and the chronic systemic disease in joint on every side in various degree.Its national sickness rate is about 0.1% according to investigations, and national patient's sum reaches more than 1,000,000.This shows that rheumatoid arthritis and ankylosing spondylitis hazardness are very big, it has a strong impact on patient's quality of life, brings heavy burden for its family and society, is to cause population of China disability and the main diseases that disables therefore.At present, western medical treatment mainly improves the state of an illness with antiinflammatory, pain relieving, hormone medicine alleviation, still can not reach the purpose of effective disease controlling development, and toxic and side effects is big, and part patient can't adhere to treatment.And the traditional Chinese medical science emphasizes that wholistic therapy, treating both the principal and secondary aspects of a disease put prevention first, and Chinese medicine is few and celebrated with untoward reaction.At present, the Chinese medicine of treatment rheumatoid arthritis, ankylosing spondylitis is more.As patent medicine Radix Tripterygii Wilfordii tablet commonly used, Tripterygium Hypoglaucum Hutch Tablet etc.And for example, the disclosed a kind of oral medicinal herb preparation for the treatment of rheumatoid arthritis of Chinese patent publication number CN1435195, it is made by a certain percentage by the prominent thorniness Formica fusca of ancient cooking vessel, Semen Strychni, Hirudo, Scorpio, Pheretima, Cinnabaris.Though these medicines have certain therapeutical effect to rheumatoid arthritis, ankylosing spondylitis, its therapeutic effect is still not ideal enough.Therefore, still there is urgent needs in people's Chinese medicine preparation that curative effect is better treated rheumatoid arthritis, ankylosing spondylitis.
Summary of the invention
Purpose of the present invention is exactly at above-mentioned disease, provide a kind for the treatment of both the principal and secondary aspects of a disease, curative effect better, the oral medicinal herb medicine that has no side effect.
Medicine of the present invention is mixed and made into by following raw medicaments in portion by weight:
Formica fusca 520-600 part, Radix Clematidis 58-63 part,
Radix Morindae Officinalis 50-60 part, Herba Epimedii 50-60 part,
Radix Ginseng 12-16 part, Radix Angelicae Sinensis 40-50 part,
Radix Astragali 76-85 part, Semen Coicis 58-62 part,
Radix Aconiti Preparata 20-25 part, Scolopendra 200-240 part,
Radix Achyranthis Bidentatae 26-32 part, Caulis Spatholobi 76-82 part,
Radix Salviae Miltiorrhizae 76-82 part, Fructus Jujubae 60-100 part,
Semen Juglandis 90-150 part.
The preferred weight of each crude drug (part) proportioning is in this medicine:
550 parts of Formica fuscas, 60 parts of Radix Clematidis,
55 parts of Radix Morindae Officinaliss, 55 parts of Herba Epimedii,
15 parts of Radix Ginsengs, 45 parts of Radix Angelicae Sinensis,
80 parts of the Radixs Astragali, 60 parts of Semen Coiciss,
25 parts of Radix Aconiti Preparatas, 230 parts of Scolopendras,
30 parts of Radix Achyranthis Bidentataes, 80 parts of Caulis Spatholobis,
80 parts of Radix Salviae Miltiorrhizaes, 80 parts in Fructus Jujubae,
120 parts of Semen Juglandis.
The present invention is prepared as honey pill agent with the above-mentioned raw materials medicine.Its preparation method is as follows: earlier with dry, clean Formica fusca, Radix Clematidis, Radix Morindae Officinalis, Herba Epimedii, Radix Ginseng, Radix Angelicae Sinensis, the Radix Astragali, Semen Coicis, Radix Aconiti Preparata, Scolopendra, Radix Achyranthis Bidentatae, Caulis Spatholobi, Radix Salviae Miltiorrhizae in accordance with regulations proportioning mix to pulverize and be coarse powder, again the regulation proportioning is dried in the air drying in the sun Fructus Jujubae (enucleation), Semen Juglandis dries to yellow with fire respectively, mix pulverizing again with above-mentioned coarse powder, cross 120 mesh sieves, with the fine powder after sieving and Mel by 1: 1 mix homogeneously, be made as honeyed pill, the heavy 6g of every ball.Instructions of taking: patient's every day oral two balls, use with boiled water or milled congee (medicine) being taken before meal morning.Three months is a course of treatment.The light and first patient of the state of an illness need take a course of treatment, and for a long time sick and patient with severe symptoms needed for two to three courses of treatment, and better curative effect can be arranged.
Theory of Chinese medical science thinks, rheumatoid arthritis, ankylosing spondylitis be the result of inside and outside two kinds of factor effects.Outer because experience cold-damp or damp and hot heresy is main, or relevant with congestion internal resistance governor vessel after the wound; Its endogenous cause of ill and innate deficiency, kidney, to superintend and direct yang deficiency relevant; Because plain body weakness, heresy was taken advantage of a weak point outside wind and cold was damp and hot, inside and outside combined pathogens, and yang-energy is not changed, and accumulates in the cold-evil, in muscles and bones, and influence muscles and bones and get nutrition mire pool, the impatency meridians, QI and blood is not smooth, thereby morbidity.So the rule of treatment answers warming and recuperating the kidney-YANG, nourishing the liver and kidney, benefiting QI and nourishing blood and collateral dredging to invigorate blood circulation.The Formica fusca nature and flavor are sweet, flat, nontoxic in the present invention's prescription, kind expelling wind and dampness, and energy eliminating blood stasis and smoothing collaterals, and strong muscles and bones, kidney invigorating and YANG supporting, nourishing blood to tranquillize the mind, consumption are solely heavy, and treating both the principal and secondary aspects of a disease is monarch drug.The Radix Clematidis wind-damp dispelling, the meridian dredging, stopping numbness pain; The all kind kidney invigorating and YANG supporting of Radix Morindae Officinalis, Herba Epimedii, expelling wind and removing dampness, three medicines share, and are ministerial drug altogether.Radix Aconiti nature and flavor suffering, hardship, temperature, system is used attenuation, but wind-damp dispelling is arrogated to oneself dispersing cold for relieving pain especially; The kind meridians ailment said due to cold or exposure of searching of Scolopendra is ended the insensitive impediment osteodynia; Semen Coicis dampness removing eliminating impediment, it is anxious to relax the muscles and bones contraction; The Radix Achyranthis Bidentatae blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening; But Caulis Spatholobi both promoting the circulation of blood is enriched blood, again can relaxing muscles and tendons and activating QI and blood in the collateral, and be adjuvant drug altogether.Use Radix Ginseng with invigorating primordial QI less in addition; Radix Astragali benefiting QI for strengthening the superficies; The Semen Juglandis warming and recuperating the kidney-YANG; Radix Angelicae Sinensis was both enriched blood, and can invigorate blood circulation again; Radix Salviae Miltiorrhizae is invigorated blood circulation and is fostered the spirit of nobility; The Fructus Jujubae QI invigorating and in, relax the property of medicine, the shared healthy energy of having decreased of then both having held up is made the hot dry property of all medicines again, is adjuvant altogether.More than all medicines share, eliminating evil and just do not hinder, set upright and do not love heresy, can reach expelling wind and removing dampness and stopping numbness pain, reinforcement and elimination in combination, the purpose for the treatment of both the principal and secondary aspects of a disease.
The present invention's medicine, obvious to rheumatoid arthritis, ankylosing spondylitis curative effect.But early stage clinical cure, mid-term can disease controlling, and late period can relief of symptoms.Late result is more satisfactory.Through select to age 17-70 year, 6 months to 38 years 87 routine patients of the course of disease by the observation of taking medicine of aforementioned instructions of taking.An observation period the lighter and a first person are a course of treatment, and for a long time sick and serious symptom person was two to three courses of treatment.Symptom complete obiteration or symptom obviously alleviate, alleviate to obtaining significant curative effect, remission, alleviates but be evident as inadequately effectively, and symptom does not have alleviation, alleviates to invalid.55 routine rheumatoid arthritis patients obtain 38 examples of significant curative effect as a result, account for 69.09%, and effective 15 examples account for 27.27%, and effective percentage reaches 96.36%; 32 routine patients with ankylosing spondylitis person's 22 examples evident in efficacy account for 68.75%, and effective 9 examples account for 28.13%, and effective percentage reaches 96.88%.This medicine has no side effect to human body, and manufacture method is simple, and medicine is with low cost, for extensive patients can bear.
The specific embodiment
Narrate three embodiment of the present invention below:
Embodiment 1
Weighting raw materials Formica fusca 580g, Radix Clematidis 59g, Radix Morindae Officinalis 52g, Herba Epimedii 52g, Radix Ginseng 13g, Radix Angelicae Sinensis 48g, Radix Astragali 82g, Semen Coicis 62g, Radix Aconiti Preparata 25g, Scolopendra 210g, Radix Achyranthis Bidentatae 31g, Caulis Spatholobi 81g, Radix Salviae Miltiorrhizae 78g, Fructus Jujubae 90g, Semen Juglandis 100g. is with above-mentioned weight drying, clean Formica fusca, Radix Clematidis, Radix Morindae Officinalis, Herba Epimedii, Radix Ginseng, Radix Angelicae Sinensis, the Radix Astragali, Semen Coicis, Radix Aconiti Preparata, Scolopendra, Radix Achyranthis Bidentatae, Caulis Spatholobi, Radix Salviae Miltiorrhizae mixes pulverizing and is coarse powder, drying in the sun Fructus Jujubae (enucleation) again dries in the air above weight, Semen Juglandis dries to yellow with fire respectively, mix pulverizing again with above-mentioned coarse powder, cross 120 mesh sieves, with the fine powder after sieving and Mel by 1: 1 mix homogeneously, be made as honeyed pill, the heavy 6g. patient of every ball (medicine) being taken before meal in morning every day two balls take with boiled water or milled congee. and three months is a course of treatment.
Embodiment 2
Weighting raw materials Formica fusca 530g, Radix Clematidis 62g, Radix Morindae Officinalis 58g, Herba Epimedii 58g, Radix Ginseng 16g, Radix Angelicae Sinensis 42g, Radix Astragali 78g, Semen Coicis 58g, Radix Aconiti Preparata 22g, Scolopendra 235g, Radix Achyranthis Bidentatae 28g, Caulis Spatholobi 78g, Radix Salviae Miltiorrhizae 81g, Fructus Jujubae 70g, Semen Juglandis 140g.Preparation method, instructions of taking are with embodiment 1.
Embodiment 3
Weighting raw materials Formica fusca 550g, Radix Clematidis 60g, Radix Morindae Officinalis 55g, Herba Epimedii 55g, Radix Ginseng 15g, Radix Angelicae Sinensis 45g, Radix Astragali 80g, Semen Coicis 60g, Radix Aconiti Preparata 25g, Scolopendra 230g, Radix Achyranthis Bidentatae 30g, Caulis Spatholobi 80g, Radix Salviae Miltiorrhizae 80g, Fructus Jujubae 80g, Semen Juglandis 120g.Preparation method, instructions of taking are with embodiment 1.
Claims (3)
1. medicine for the treatment of rheumatoid arthritis, ankylosing spondylitis is characterized in that it is formulated by following raw medicaments in portion by weight:
Formica fusca 520-600 part, Radix Clematidis 58-63 part,
Radix Morindae Officinalis 50-60 part, Herba Epimedii 50-60 part,
Radix Ginseng 12-16 part, Radix Angelicae Sinensis 40-50 part,
Radix Astragali 76-85 part, Semen Coicis 58-62 part,
Radix Aconiti Preparata 20-25 part, Scolopendra 200-240 part,
Radix Achyranthis Bidentatae 26-32 part, Caulis Spatholobi 76-82 part,
Radix Salviae Miltiorrhizae 76-82 part, Fructus Jujubae 60-100 part,
Semen Juglandis 90-150 part.
2. the medicine of treatment rheumatoid arthritis according to claim 1, ankylosing spondylitis is characterized in that, the weight proportion of each crude drug is:
550 parts of Formica fuscas, 60 parts of Radix Clematidis,
55 parts of Radix Morindae Officinaliss, 55 parts of Herba Epimedii,
15 parts of Radix Ginsengs, 45 parts of Radix Angelicae Sinensis,
80 parts of the Radixs Astragali, 60 parts of Semen Coiciss,
25 parts of Radix Aconiti Preparatas, 230 parts of Scolopendras,
30 parts of Radix Achyranthis Bidentataes, 80 parts of Caulis Spatholobis,
80 parts of Radix Salviae Miltiorrhizaes, 80 parts in Fructus Jujubae,
120 parts of Semen Juglandis.
3. claim 1 or 2 described treatment rheumatoid arthritiss, the preparation method of the medicine of ankylosing spondylitis, it is characterized in that, earlier with drying, clean Formica fusca, Radix Clematidis, Radix Morindae Officinalis, Herba Epimedii, Radix Ginseng, Radix Angelicae Sinensis, the Radix Astragali, Semen Coicis, Radix Aconiti Preparata, Scolopendra, Radix Achyranthis Bidentatae, Caulis Spatholobi, Radix Salviae Miltiorrhizae proportioning mixing pulverizing in accordance with regulations is coarse powder, again the cold of regulation proportioning is dried the Fructus Jujubae after the enucleation, Semen Juglandis dries to yellow with fire respectively, mix pulverizing again with above-mentioned coarse powder, cross 120 mesh sieves, with the fine powder after sieving and Mel by 1: 1 mix homogeneously, be made as honeyed pill, the heavy 6g of every ball.
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| Application Number | Priority Date | Filing Date | Title |
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| CN200510096296A CN1958052B (en) | 2005-11-04 | 2005-11-04 | Medication for treating rheumatoid arthritis, ankylosing spondylitis |
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| CN200510096296A CN1958052B (en) | 2005-11-04 | 2005-11-04 | Medication for treating rheumatoid arthritis, ankylosing spondylitis |
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| CN1958052A CN1958052A (en) | 2007-05-09 |
| CN1958052B true CN1958052B (en) | 2010-05-12 |
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| CN111803598A (en) * | 2020-07-22 | 2020-10-23 | 昆明科晔生物技术有限公司 | Traditional Chinese medicine preparation for eliminating dampness and dredging collaterals |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1557383A (en) * | 2004-02-10 | 2004-12-29 | 广西来宾金钱草药业有限公司 | Bi-ant contained dampness dispelling and collaterals dredging medicinal capsule |
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| CN1557383A (en) * | 2004-02-10 | 2004-12-29 | 广西来宾金钱草药业有限公司 | Bi-ant contained dampness dispelling and collaterals dredging medicinal capsule |
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