CN1943696A - An external use agent for treating chronic rhinitis and nasosinusitis - Google Patents

An external use agent for treating chronic rhinitis and nasosinusitis Download PDF

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CN1943696A
CN1943696A CN 200610124825 CN200610124825A CN1943696A CN 1943696 A CN1943696 A CN 1943696A CN 200610124825 CN200610124825 CN 200610124825 CN 200610124825 A CN200610124825 A CN 200610124825A CN 1943696 A CN1943696 A CN 1943696A
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fructus
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CN100475250C (en
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吴鹏
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Abstract

This invention provides an external use medincet for treating chronic rhinitis and nasosinusitis. It is prepared by using the following Chinese medical ingredients according to their weight ratio: American ginseng 15-3, peony root bark 12-5,Chinese angelica root 12-5,towelgourd vascular bundles 10-5,balloon-flower 10-5,puncturevine caltrap fruit 10-5, coptis rhizome0-5,membranous milkvetch root 10-5,ginseng 10-5,sevenlobed yam rhizome 8-5,pumice8-5,fructus forsythiae 8-5,Dahurian angelica root 5-1,biond magnolia flower-bud 5-1,skebia stem 5-1,siberian cocklebur fruit 5-1,cassiabarktree bark 3-1,manchurian whildginger herb 3-1.In the aspect of the medical application, it is convenient and easy to use with light side effects, no irritatations to the skin and obvious curative effects. According to statistics that the total effective ratio for treating chronic rhinitis, chronic nasosinusitis is above 95%.

Description

The medicine for external use of treatment chronic rhinitis, sinusitis
Affiliated technical field:
The invention belongs to a kind of Chinese patent medicine, especially belong to a kind of treatment chronic rhinitis that adopts Chinese medicine to be mixed with, the medicine for external use of chronic sinusitis.
Background technology:
Doctor trained in Western medicine thinks that chronic rhinitis, chronic sinusitis mostly are the chronic inflammatory disease of nasal membrane and submucous tissue plumpness, hypertrophy, myxedema, often do not get timely medical treatment or malpractice and not thorough because of acute stage, and it is chronic to cause delay to become: (1) acute rhinitis is shown effect repeatedly, the expansion of nasal membrane deep-level blood vessel, especially the concha nasalis inferior cavernous sinusoids is the most obvious, causes the concha nasalis enlargement; The mucous gland function is active, secretion increasing; Inflammatory cell infiltration is arranged around blood vessel and the body of gland; On simple rhinitis's basis, pathological changes continues development, causes proliferation of fibrous tissue, causes nasal membrane, tela submucosa even periosteum and sclerotin plumpness, and is wherein obvious with concha nasalis inferior; Nodositas, Fructus Mori shape even polypoid can take place and change in turbinate mucosa, often can cause olfactory disorder more than mucosa swelling or nasal discharge; (2) physics or chemical stimulation: it is excessive to have a liking for tobacco and wine, and harmful dust, chemical gas in life or the working environment, and overheated, supercool, dry, malaria etc. contact for a long time and stimulate nasal membrane, causes mucosal injury and suffers from primary disease.
Chinese medicine thinks that chronic rhinitis, chronic sinusitis are to belong to " stuffy nose ", " nasal obstruction ", " being jammed " " nasal sinusitis " category, the disease that belongs to interior-deficiency, for lung qi deficiency and coldness and deficiency-weakness of spleen-QI cause: (1) is because of affection of exogenous wind-cold, strongly fragrant and the heat-transformation of wind heat or wind and cold, untreated, or treatment is not thorough, and evil poison is stranded in the nose key; (2) because of affection of exogenous wind-cold, wind heat or wind and cold are gone into lung by nose, and lung meridian hinders that then lung is inappropriate falls, so see nasal obstruction, inappropriate the falling of (3) lung qi can cause qi depression to blood stasis, the sx of having a stuffy nose this moment, and lung qi is plain empty, and healthy energy is unable drives, and heresy is gone out, the easy cohesion nose key that is jammed, and protracted course of disease; (4) because of the lung qi deficiency and coldness, do not declare for a long time and separate, the turbid expectorant that changes into of body fluid, retention is smouldered, clear YANG failing to ascend turbid YIN failing to descend and go up to cover clear key, wind and cold is gone into brain, strongly fragrant heat-transformation of a specified duration, upward smoked clear key forms nasal sinusitis.
Methods such as existing western medical treatment use anti-inflammation drugs or the detumescence of contraction local vascular mostly number have only curative effect for the moment, mitigation symptoms for the moment only, take topical application nasal drop, spray, electric coagulation, cryotherapy, operative treatment or the like, it is unobstructed mostly can to improve nasal meatus for the moment, but can't thoroughly deal with problems, causing resuscitation with aromatic drugs is too laid particular stress in treatment on the existing mostly traditional Chinese medical science, the most of curative effects of these methods are not remarkable, can only play the effect of the respite state of an illness, and can not effect a radical cure, therefore obstinate shows effect repeatedly, causes the state of an illness to increase the weight of gradually; No matter the treatment time of the oral Drug therapy chronic rhinitis of Chinese and western medicine, chronic sinusitis is longer, take medicine for a long time Liver and kidney is caused certain burden, just act on the position of illness after also having oral medicine to decompose through the liver absorption, curative effect also is subjected to certain influence and lessens the curative effect; Special Chinese medicine decoction need decoct, and time-consuming effort again is inconvenient on decocting.
Summary of the invention:
What the object of the present invention is to provide that a kind of pure Chinese medicine is mixed with can eliminate symptom rapidly and cure the medicine for external use of chronic rhinitis, chronic sinusitis.
The present invention is a foundation: 1., clinical report of record Radix Angelicae Sinensis " is treated rhinitis with 5% Radix Angelicae Sinensis injection injection fragrant cave, Yintang acupoint " in " Chinese medicine voluminous dictionary "; 2., the effect of all treatment nasal obstructions, rhinitis, nasal sinusitis, nasal polyp etc. is controlled in all extra nerve points, i.e. points not mentioned in the ancient medical classics (Shangyingxiang, nose stream, BITONG, nose are worn) of record fragrant cave and nose cave in " acupuncture voluminous dictionary "; 3., about treating the tcm theory of chronic rhinitis, chronic sinusitis; Carry out the comprehensive study analysis, develop the medicine for external use of treatment chronic rhinitis, chronic sinusitis, inventor's called after " nose cream relaxes ".
According to theory of Chinese medical science, they are the cards that belong to interior-deficiency for chronic rhinitis, chronic sinusitis, for lung qi deficiency and coldness and deficiency-weakness of spleen-QI cause, controlling to be basis with tonifying the lung gas, and because of being prolonged illness, and expectorant is given birth in prolonged illness, phlegm-damp is because of accumulating Cheng for many years mass in the abdomen, so on the basis that the lung qi dispersing that dispels the wind is had one's ideas straightened out, also need reduce phlegm, expectorant, blood circulation promoting and blood stasis dispelling, eliminating stagnation Chu Disorder, collateral dredging dehumidifying removing food stagnancy, so just increase greatly treating the curative effect of chronic rhinitis, chronic sinusitis; No matter the treatment time of the oral Drug therapy chronic rhinitis of Chinese and western medicine, chronic sinusitis is longer, take medicine for a long time Liver and kidney is caused certain burden, just act on the position of illness after also having oral medicine to decompose through the liver absorption, curative effect also is subjected to certain influence and lessens the curative effect, medicine for external use of the present invention was directly wiped in nose week, directly acted on the illness position by the acupuncture point in nose week and the absorption of skin; For instant effect, and the absorption of skin point, the medicine of increase promoting blood circulation in medicinal application.Long-term prescription is harmless to health, and is easy to use, and to the skin nonirritant, side effect is little, and is evident in efficacy, the cure rate height.
Preparation of the present invention comes replenishing and restoring lung-QI with Radix Ginseng (preferred Radix Ginseng Rubra), Radix Panacis Quinquefolii, Radix Astragali; With Radix Platycodonis, Pumex, Bulbus Fritillariae Thunbergii, Flos Farfarae, Radix Asteris, Retinervus Luffae Fructus, Semen Raphani, Alumen reduce phlegm, expectorant; Come blood circulation promoting and blood stasis dispelling, eliminating stagnation Chu Disorder with Cortex Moutan, Radix Angelicae Sinensis, dried Pheretima (being that Lumbricus does), Fructus Tribuli, Fructus Forsythiae, Caulis Akebiae, Rhizoma Atractylodis, Semen Persicae, Fructus Aurantii; With Retinervus Luffae Fructus, Radix Platycodonis, the Radix Angelicae Dahuricae, Flos Magnoliae, Bi , Fructus Xanthii, Herba Asari, dispel the wind, lung qi dispersing has one's ideas straightened out; Come collateral dredging dehumidifying, removing food stagnancy with Retinervus Luffae Fructus, Rhizoma Coptidis, Bi , Alumen, Cortex Cinnamomi; Come the skin absorbs of promoting blood circulation, increase external used medicine with Caulis Akebiae, Cortex Cinnamomi, Semen Persicae.The function of write up is in " Chinese medicine voluminous dictionary ":
1, Radix Panacis Quinquefolii: lung benefiting the moon, clear asthenic fire; 2, Cortex Moutan: clearing away heat and cooling blood, dissipating blood stasis, control and send out a Ban, mass in the abdomen; 3, dried Pheretima: heat clearing away, collateral dredging, " Chinese medicine elite ": " collateral dredging, detoxify, control nasal polyp "; 4, Bulbus Fritillariae Thunbergii: removing heat-phlegm, powder detoxifcation, " book on Chinese herbal medicine justice ": " Bulbus Fritillariae Thunbergii purging with bitter and cold drugs and can eliminating stagnation "; 5, Radix Angelicae Sinensis: benefiting blood and regulating blood circulation, clinical report treatment rhinitis; 6, Retinervus Luffae Fructus: dredge the meridian passage, removing heat-phlegm, " book on Chinese herbal medicine is just read ": " Retinervus Luffae Fructus is separated pathogenic heat.Evanescence of heat then wind goes, and the unlikely combination of body fluid in the network and be expectorant becomes all diseases of toxic swelling, so cloud detoxifcation ear."; 7, Radix Platycodonis: open lung qi dispersing gas, the evacuation of pus of eliminating the phlegm; 8, Fructus Tribuli: loose wind, the therapeutic method to keep the adverse QI flowing downwards, promoting the circulation of blood, control headache, mass in the abdomen, scrofula, " Chinese medicine elite ": " cure mainly nasal obstruction anodimia (anosmia); 9, Rhizoma Coptidis: pathogenic fire purging dampness, detoxifcation parasite killing, clinical report treatment atrophic rhinitis and last frontal sinusitis; 10, Radix Astragali: benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening; 11, Radix Ginseng (preferred Radix Ginseng Rubra): strongly invigorating primordial QI, take off and promote the production of body fluid, calm the nerves admittedly; 12, Bi : dispel the wind, dampness removing, " book on Chinese herbal medicine justice ": " Bi , performance circulation venation and relieving rigidity of muscles and joints."; 13, Pumex: the lung heat clearing fire, change old expectorant, softening the hard mass, treating stranguria; 14, Fructus Forsythiae: heat-clearing and toxic substances removing, mass dissipating and swelling eliminating, " Records of Tradition Chinese and Western Medicine in Combination ": " the Fructus Forsythiae tool rises the power that floating a surname looses ... the kind disease of controlling the head, and all headaches, ophthalmalgia, tooth are painful, nasal sinusitis or watery nasal discharge become the sinusitis with purulent discharge card, all can lead it."; 15, the Radix Angelicae Dahuricae: dispel the wind, dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis 16, Flos Magnoliae: dispel the wind, sensible, control headache, nasal sinusitis, obstructed, the toothache of nasal obstruction.17, Caulis Akebiae: pathogenic fire purging row water, promoting blood circulation, " Chinese medicine elite ": " cure mainly obstructed, the nasal polyp Huo Bi Weng of nasal obstruction ...; 18, Rhizoma Atractylodis: spleen invigorating, dampness, resolving depression, ward off dirty." beautiful autumn medicine separate ": " dry native diuretic, let out drink expectorant, clots absorbing, dissipating depression of QI, remove Lou, change addiction , Chu Disorder ... "; 19, Semen Persicae: removing blood stasis, clots absorbing; 20, Semen Raphani: therapeutic method to keep the adverse QI flowing downwards Dingchuan, eliminate indigestion and phlegm; 21, Fructus Aurantii: dispelling the stagnated QI, row expectorant, removing food stagnancy; 22, Flos Farfarae: nourishing the lung to keep the adverse QI downward, antitussive reduces phlegm; 23, Radix Asteris: warming the lung, the therapeutic method to keep the adverse QI flowing downwards, expectorant, antitussive; 24, Fructus Xanthii: loose wind, pain relieving, damp eliminating, parasite killing, control headche due to wind-cold, nasal sinusitis, toothache etc.; 25, Herba Asari: expelling wind and cold, Hang Shui, have one's ideas straightened out, control air-cooled headache, nasal sinusitis, toothache etc.; 26, Alumen: expectorant, dampness, antidiarrheal, hemostasis, detoxifcation, parasite killing, Compendium of Material Medica: " ... the hemostasis analgesic therapy, meat is disliked in erosion, gives birth to good meat ... "; 27, Cortex Cinnamomi: complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation.
The present invention prepares the medicine for external use of treatment chronic rhinitis, chronic sinusitis according to above principle, and it is by comprising that the following weight Chinese medicinal raw materials makes:
15~3 parts of Radix Panacis Quinquefoliis, 12~5 parts of Cortex Moutans, 12~5 parts of Radix Angelicae Sinensis, 10~5 parts of Retinervus Luffae Fructuss, 10~5 parts of Radix Platycodoniss, 10~5 parts of Fructus Tribulis, 10~5 parts of Rhizoma Coptidis, 10~5 parts of Radix Astragali, 10~5 parts of Radix Ginsengs (Radix Ginseng Rubra), 8~5 parts of Bi , 8~5 parts of Pumexs, 8~5 parts of Fructus Forsythiaes, 5~1 parts of the Radixs Angelicae Dahuricae, 5~1 parts of Flos Magnoliaes, 5~1 parts of Caulis Akebiaes, 5~1 parts of Fructus Xanthii, 3~1 parts of Cortex Cinnamomis, 3~1 parts of Herba Asaris.Some slight side effect appear in the present invention's this prescription sometimes, as: it is dry that nasal cavity appears in the somebody, and drug effect is more slow etc.
The present invention also can add the following weight Chinese medicinal raw materials and make on above-mentioned main formula basis:
10~5 parts of Bulbus Fritillariae Thunbergiis, 10~5 parts of dried Pheretima, 5~1 parts of Rhizoma Atractylodis, 5~1 parts in Semen Persicae, 5~1 parts of Semen Raphanis, 5~1 parts of Fructus Aurantiis, 3~1 parts of Flos Farfaraees, 3~1 parts of Radix Asteriss, 3~1 parts of Alumens, wherein one of Rhizoma Atractylodis or Semen Raphani must contain.The present invention can heighten the effect of a treatment after adding in above-mentioned 9 kinds of Chinese medicines 2 kinds at least, eliminates side effect substantially.
Preparation method of the present invention:
1, takes by weighing Radix Panacis Quinquefolii, Cortex Moutan, Radix Angelicae Sinensis, Retinervus Luffae Fructus, Radix Platycodonis, Fructus Tribuli, Rhizoma Coptidis, Radix Astragali, Radix Ginseng (Radix Ginseng Rubra), Bi , Pumex, Fructus Forsythiae, the Radix Angelicae Dahuricae, Flos Magnoliae, Caulis Akebiae, Fructus Xanthii, the Cortex Cinnamomi of above-mentioned formula ratio, the Chinese medicine preparation dosage of Herba Asari in proportion, pouring medicine into medicinal cupping uses cold water soak after 15~30 minutes, changed the slow fire constantly boiling into 20~30 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached; Medicinal residues add and change literary composition after hot water elder generation intense fire is fried boiling into for continuing 20~30 minutes, and then medicine juice is leached.Twice medicine juice merged the medicinal liquid of 50%~250% (percentage by weight) that be concentrated into original crude drug amount, and this medicinal liquid that is obtained can use.Making the unguentum use when needs can be with spissated medicinal liquid, after 25 parts in vaseline of percentage ratio adding, 7.5 parts of glycerol, 6 parts of triethanolamine, 3 parts of lanolines, 15 parts of stearic acid and mud is by weight moored golden 0.25 part, be heated to more than 80 ℃, treat to stop after they liquefy fully heating, it is stirred to condensation just becomes ointment.
2, the present invention also can increase several or whole in Bulbus Fritillariae Thunbergii, dried Pheretima, Rhizoma Atractylodis, Semen Persicae, Semen Raphani, Fructus Aurantii, Flos Farfarae, Radix Asteris, nine kinds of Chinese medicines of Alumen again according to above main Chinese medicine preparation, wherein one of Rhizoma Atractylodis or Semen Raphani must contain, take by weighing dosage in the ratio of prescription and pour medicinal cupping into cold water soak after 15~30 minutes, changed the slow fire constantly boiling into 20~30 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and change literary composition after the first in the same old way intense fire of hot water is fried boiling into for continuing 20~30 minutes, and then medicine juice is leached.Twice medicine juice merged the medicinal liquid of 50%~250% (percentage by weight) that be concentrated into original crude drug amount, and this medicinal liquid can use.Making the unguentum use when needs can be with spissated medicinal liquid, after 25 parts in vaseline of percentage ratio adding, 7.5 parts of glycerol, 6 parts of triethanolamine, 3 parts of lanolines, 15 parts of stearic acid and mud is by weight moored golden 0.25 part, be heated to more than 80 ℃, treat to stop after they liquefy fully heating, it is stirred to condensation just becomes ointment.
The present invention has equal effect no matter be to make water preparation, tincture, unguentum, cream all can use.
Therapeutic Method:
Use external-application cream of the present invention wipe in the nasion of external nose to the wing of nose with the position of buccal intersection, two wing of nose lower edges between link to each other position with the buccal intersection, comprising fragrant cave and nose week extra nerve points, i.e. points not mentioned in the ancient medical classics (Shangyingxiang, nose stream, BITONG, nose are worn) or the like.Treatment chronic rhinitis, chronic sinusitis are to wipe 1~3 time every day according to the state of an illness, based on before sleeping evening once, about 0.1~0.2 gram of each consumption.
Concrete curative effect:
The medicine for external use that adopts main formula of the present invention to make, easy to use in medicinal application, side effect is little, and is to the skin nonirritant, evident in efficacy.The patient of nasal obstruction generally applies medicinal lotion or ointment and feels that promptly nasal meatus is unobstructed in 30 minutes; The patient that the state of an illness of chronic rhinitis, chronic sinusitis is lighter is general, and a week back symptom disappears substantially, two months patient of continuous use drug withdrawal after 1 year relapse rate be below 5%; The heavier patient of the state of an illness (concha nasalis plumpness, nasal polyp, nasal septum skew, anodimia) medication rises morning on the secondth feels that promptly nasal mucus increases, continue to use and to reduce gradually, general one transference cure in thoughtful two months, use continuously trimestral patient drug withdrawal after 1 year relapse rate be below 10%.Adopt main formula of the present invention to increase the medicine for external use that makes behind in Bulbus Fritillariae Thunbergii, dried Pheretima, Rhizoma Atractylodis, Semen Persicae, Semen Raphani, Fructus Aurantii, Flos Farfarae, Radix Asteris, nine kinds of Chinese medicines of Alumen at least 2 kinds again, heighten the effect of a treatment, obviously eliminate side effect, be embodied in: the patient of nasal obstruction applies medicinal lotion or ointment and feels that promptly nasal meatus is unobstructed in 30 minutes; The lighter patient of the state of an illness of chronic rhinitis, chronic sinusitis after 5 days symptom disappear substantially, two months patient of continuous use drug withdrawal after 1 year relapse rate be below 5%; The heavier patient of the state of an illness (concha nasalis plumpness, nasal polyp, nasal septum skew, anodimia) medication rises morning on the secondth feels that promptly nasal mucus increases, continue to use and to reduce gradually, transference cure in 5 days to 1 first quarter moons, use continuously trimestral patient drug withdrawal after 1 year relapse rate be below 10%, and phenomenon such as dry nasal cavity does not obviously appear.The total effective rate for the treatment of chronic rhinitis, chronic sinusitis according to statistics reaches more than 90%, has no side effect.For using the present invention through using electric coagulation or cryotherapy treatment twice above (containing twice), the treatment course of disease is more of a specified duration, most of patient's unsatisfactory curative effect.
Clinical operating position and effect:
The present invention made first in nineteen ninety-five, and used this medicine treatment chronic rhinitis, chronic sinusitis, wipe 1~3 time every day according to the state of an illness, based on before sleeping evening once, each consumption is 0.1~0.2 gram.The patient of nasal obstruction generally applies medicinal lotion or ointment and feels that promptly nasal meatus is unobstructed in 30 minutes; General 5 days of the patient that the state of an illness of chronic rhinitis, chronic sinusitis is lighter to one week the back symptom disappear substantially, two months patient of continuous use drug withdrawal after 1 year relapse rate be below 5%; The heavier patient of the state of an illness (concha nasalis plumpness, nasal polyp, nasal septum skew, anodimia) medication rises morning on the secondth feels that promptly nasal mucus increases, continue to use and to reduce gradually, general 5 days transference cures in thoughtful 1 first quarter moon to two month, use continuously trimestral patient drug withdrawal after 1 year relapse rate be below 10%.For using the present invention through using electric coagulation or cryotherapy treatment twice above (containing twice), the treatment course of disease is more of a specified duration, most of patient's unsatisfactory curative effect.Till 2006, the case of treatment chronic rhinitis, chronic sinusitis etc. has 300 many cases, through rough Statistics chronic rhinitis 230 examples, and chronic sinusitis 70 examples, the chronic rhinitis effective percentage is more than 92%, and the chronic sinusitis effective percentage is more than 87%.Now details are as follows in conjunction with clinical data:
Model case 1
Certain man of week, 58 years old (nineteen ninety-five), certain worker of company suffer from chronic rhinitis when readme is young, obstructed year surplus in the of ten of anodimia and nose.Use the present invention, use every day three times, rising in 1st just has dense nasal mucus to discharge, nasal obstruction begins to take a turn for the better after 15 days, olfactory sensation begins to recover to some extent after one month, continue two months all transference cures of medication, and snored in bed evening might as well, advise to change the every day of medication just before going to bed and once continue medication drug withdrawal again after month.Do not see morbidity in 1998, the symptom of nasal obstruction is only arranged when flu, with promptly disappearing after the flu recovery from illness.Do not get in touch again because of the relation of work later on.
Model case 2
Chen man, 45 years old (1996), certain cadre of company, readme is suffered from surplus the allergic rhinitis ten year, rise morning every day must sneeze ten surplus, the sensation nasal meatus is dried itches, hypopnea.Use the present invention, every day three times, felt on the 1st that dried itching took a favorable turn, idol has sticking nasal mucus to discharge, medication after five days morning play sneeze and obviously reduce, nasal meatus is no longer dried itches, 15 backs are risen and only make a call to one or two sneeze occasionally mornings, use symptom complete obiteration after month, advise to change medication every night and once continue to use a drug withdrawal again in month.Recurrence is not seen in a year and a half further consultation afterwards.
Model case 3
Chen man, 41 years old (2004), certain cadre of unit, readme nasal obstruction, rhinorrhea had more than 5 years, be chronic rhinitis after diagnosing, once arrived hospital's specific treatment, by oral medication and the treatment of external nasal drop, through repeatedly all just recurrences after a while after drug withdrawal of treatment,, abandoning cure is more than 2 years.Examine in December, 2004, use the present invention, the aftersensation symptom was clearly better, alleviated at twice, the three day every day, and transference cure after seven days is advised to change and continued to use drug withdrawal after two months once a day.So far not recurrence.
Model case 4
Wu woman, 36 years old (2002), the civil servant, suffer from chronic rhinitis during readme senior middle school, working more than a year, anodimia appears in nose, once at the capable electric coagulation of hospital's training, treat after 1 year that to occur nasal obstruction again obstructed, adopt cryotherapy then, after this epistaxis just often appear, slight nasal obstruction symptom is used the present invention, every day three times, the transference cure of having a stuffy nose after one month, epistaxis reduces to some extent, do not had epistaxis after three months and occurred, but epistaxis appears again in drug withdrawal after two months, advise and continue to use that epistaxis disappears after one month, but after the drug withdrawal on diet the polyphagia maror epistaxis can appear.Use once before as long as adhere to so far sleeping every night, under the situation of fasting maror, just do not have the epistaxis symptom and occur.
Model case 5
Wang woman, 17 years old (2004), student, readme primary school senior class is just suffered from chronic rhinitis, goes to a doctor to hospital's training during the junior two, is diagnosed as right concha nasalis hypertrophic chronic rhinitis, the treatment of row electric coagulation, nasal meatus is unobstructed after treating, but hyposmia; For the moment nasal meatus is obstructed again at height, is diagnosed as the chronic rhinitis of diaphragm right avertence in two concha nasalis plumpnesses, the nose through training, more oral Chinese patent medicine and Western medicine but effect is undesirable; Examine upon somebody's introduction, give the present invention treatment, every day three times, the toughness nasal mucus is discharged two days later, the right nasal meatus nasal obstruction in one week back is alleviated, and the left nasal meatus nasal obstruction in three week backs is alleviated, medication after one month olfactory sensation begin to recover, medication symptoms of rhinitis after two months disappears substantially, advise training to use inspect by instrument, diaphragm right avertence slightly in the nose is only advised to change and is used once before sleeping every day, continue medication drug withdrawal again in two months, so far not recurrence.
Model case 6
Chen woman, 27 years old (2003), grade teacher, chronic sinusitis is in junior middle school promptly suffered from readme, and nasal obstruction seriously, often has giddy and headache during senior middle school, to the capable jaw hole puncture of hospital's training flush operation, recurrence again after a year.In examining over 2003, use every day of the present invention three times, rising morning on the 3rd promptly has a large amount of dense nasal mucus to discharge, and does not have dense nasal mucus to discharge behind the two weeks, and dizzy and headache symptom disappears substantially; Advise to change and once continue medication drug withdrawal in two months before sleeping every day, so far recurrence.
The specific embodiment:
The present invention is described in detail below in conjunction with example:
Embodiment 1
Take by weighing Radix Panacis Quinquefolii 12 grams, Cortex Moutan 8 grams, Radix Angelicae Sinensis 5 grams, Retinervus Luffae Fructus 8 grams, Radix Platycodonis 6 grams, Fructus Tribuli 5 grams, Rhizoma Coptidis 10 grams, Radix Astragali 5 grams, Radix Ginseng Rubra 5 grams, Bi  8 grams, Pumex 6 grams, Fructus Forsythiae 5 grams, the Radix Angelicae Dahuricae 5 grams, Flos Magnoliae 3 grams, Caulis Akebiae 1 gram, Fructus Xanthii 5 grams, Cortex Cinnamomi 1 gram and Herba Asari 1 gram mix, pouring medicine into medicinal cupping uses cold water soak after 20 minutes, changed the slow fire constantly boiling into 25 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 20 minutes after hot water elder generation intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 150 grams.
Embodiment 2
The 150 gram medicinal liquids of obtaining of embodiment 1 are added vaseline 37.5 grams, glycerol 11.25 grams, triethanolamine 9 grams, lanoline 4.5 grams, stearic acid 22.5 grams and mud pool gold 0.375 gram, be heated to 85 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation, ointment.
Embodiment 3
Take by weighing Radix Panacis Quinquefolii 6 grams, Cortex Moutan 12 grams, Radix Angelicae Sinensis 8 grams, Retinervus Luffae Fructus 5 grams, Radix Platycodonis 10 grams, Fructus Tribuli 8 grams, Rhizoma Coptidis 5 grams, Radix Astragali 8 grams, Radix Ginseng Rubra 6 grams, Bi  5 grams, Pumex 8 grams, Fructus Forsythiae 8 grams, the Radix Angelicae Dahuricae 1 gram, Flos Magnoliae 5 grams, Caulis Akebiae 3 grams, Fructus Xanthii 3 grams, Cortex Cinnamomi 2 grams and Herba Asari 2 grams mix, pouring medicine into medicinal cupping uses cold water soak after 20 minutes, changed the slow fire constantly boiling into 25 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 20 minutes after hot water elder generation intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 200 grams.
Embodiment 4
The 200 gram medicinal liquids of obtaining of embodiment 3 are added vaseline 50 grams, glycerol 15 grams, triethanolamine 12 grams, lanoline 6 grams, stearic acid 30 grams and mud pool gold 0.5 gram, be heated to 85 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.
Embodiment 5
Take by weighing Radix Panacis Quinquefolii 3 grams, Cortex Moutan 5 grams, Radix Angelicae Sinensis 10 grams, Retinervus Luffae Fructus 10 grams, Radix Platycodonis 5 grams, Fructus Tribuli 10 grams, Rhizoma Coptidis 8 grams, Radix Astragali 10 grams, Radix Ginseng 10 grams, Bi  6 grams, Pumex 5 grams, Fructus Forsythiae 6 grams, the Radix Angelicae Dahuricae 3 grams, Flos Magnoliae 1 gram, Caulis Akebiae 5 grams, Fructus Xanthii 1 gram, Cortex Cinnamomi 3 grams and Herba Asari 3 grams mix, pouring medicine into medicinal cupping uses cold water soak after 30 minutes, changed the slow fire constantly boiling into 25 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and change slow fire after hot water elder generation intense fire is fried boiling into for continuing 20 minutes, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 100 grams.
Embodiment 6
The 100 gram medicinal liquids of obtaining of embodiment 5 are added vaseline 25 grams, glycerol 7.5 grams, triethanolamine 6 grams, lanoline 3 grams, stearic acid 15 grams and mud pool gold 0.25 gram, be heated to 90 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.
Embodiment 7
Take by weighing Radix Panacis Quinquefolii 12 grams, Cortex Moutan 7 grams, Radix Angelicae Sinensis 6 grams, Retinervus Luffae Fructus 9 grams, Radix Platycodonis 8 grams, Fructus Tribuli 7 grams, Rhizoma Coptidis 9 grams, Radix Astragali 5 grams, Radix Ginseng Rubra 5 grams, Bi  8 grams, Pumex 8 grams, Fructus Forsythiae 5 grams, the Radix Angelicae Dahuricae 3 grams, Flos Magnoliae 2 grams, Caulis Akebiae 4 grams, Fructus Xanthii 3 grams, Cortex Cinnamomi 2 grams, Herba Asari 2 grams, Bulbus Fritillariae Thunbergii 8 grams, dried Pheretima 5 grams, Rhizoma Atractylodis 5 grams, Semen Persicae 5 grams, Semen Raphani 5 grams, Fructus Aurantii 1 gram, Flos Farfarae 1 gram, Radix Asteris 1 gram and Alumen 2 grams mix, pouring medicine into medicinal cupping uses cold water soak after 30 minutes, changed the slow fire constantly boiling into 30 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 25 minutes after hot water elder generation intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 300 grams.
Embodiment 8
The 300 gram medicinal liquids of obtaining of embodiment 7 are added vaseline 75 grams, glycerol 22.5 grams, triethanolamine 18 grams, lanoline 9 grams, stearic acid 45 grams and mud pool gold 0.75 gram, be heated to 85 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.
Embodiment 9
Take by weighing Radix Panacis Quinquefolii 10 grams, Cortex Moutan 8 grams, Radix Angelicae Sinensis 7 grams, Retinervus Luffae Fructus 6 grams, Radix Platycodonis 5 grams, Fructus Tribuli 6 grams, Rhizoma Coptidis 6 grams, Radix Astragali 8 grams, Radix Ginseng Rubra 6 grams, Bi  7 grams, Pumex 6 grams, Fructus Forsythiae 7 grams, the Radix Angelicae Dahuricae 4 grams, Flos Magnoliae 3 grams, Caulis Akebiae 4 grams, Fructus Xanthii 3 grams, Cortex Cinnamomi 3 grams, Herba Asari 2 grams, Bulbus Fritillariae Thunbergii 10 grams, dried Pheretima 10 grams, Rhizoma Atractylodis 1 gram, Semen Persicae 2 grams, Semen Raphani 1 gram, Fructus Aurantii 1 gram, Flos Farfarae 1 gram, Radix Asteris 1 gram, Alumen 1 gram mixes, pouring medicine into medicinal cupping uses cold water soak after 30 minutes, changed the slow fire constantly boiling into 30 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 30 minutes after hot water elder generation intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 300 grams.
Embodiment 10
The 300 gram medicinal liquids of obtaining of embodiment 9 are added vaseline 75 grams, glycerol 22.5 grams, triethanolamine 18 grams, lanoline 9 grams, stearic acid 45 grams and mud pool gold 0.75 gram, be heated to 90 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.
Embodiment 11
Take by weighing Radix Panacis Quinquefolii 5 grams, Cortex Moutan 5 grams, Radix Angelicae Sinensis 5 grams, Retinervus Luffae Fructus 5 grams, Radix Platycodonis 5 grams, Fructus Tribuli 5 grams, Rhizoma Coptidis 5 grams, Radix Astragali 10 grams, Radix Ginseng Rubra 10 grams, Bi  5 grams, Pumex 5 grams, Fructus Forsythiae 6 grams, the Radix Angelicae Dahuricae 2 grams, Flos Magnoliae 1 gram, Caulis Akebiae 1 gram, Fructus Xanthii 1 gram, Cortex Cinnamomi 1 gram, Herba Asari 1 gram, Bulbus Fritillariae Thunbergii 5 grams, dried Pheretima 6 grams, Rhizoma Atractylodis 3 grams, Semen Persicae 1 gram, Semen Raphani 1 gram, Fructus Aurantii 1 gram, Flos Farfarae 3 grams, Radix Asteris 1 gram, Alumen 1 gram, pouring medicine into medicinal cupping uses cold water soak after 20 minutes, changed the slow fire constantly boiling into 20 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 20 minutes after the hot water intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 50 grams.
Embodiment 12
The 50 gram medicinal liquids of obtaining of embodiment 11 are added vaseline 12.5 grams, glycerol 3.75 grams, triethanolamine 3 grams, lanoline 1.5 grams, stearic acid 7.5 grams and mud pool gold 0.125 gram, be heated to 85 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.
Embodiment 13
Take by weighing Radix Panacis Quinquefolii 10 grams, Cortex Moutan 10 grams, Radix Angelicae Sinensis 10 grams, Retinervus Luffae Fructus 10 grams, Radix Platycodonis 10 grams, Fructus Tribuli 10 grams, Rhizoma Coptidis 10 grams, Radix Astragali 10 grams, Radix Ginseng Rubra 10 grams, Bi  6 grams, Pumex 6 grams, Fructus Forsythiae 6 grams, the Radix Angelicae Dahuricae 3 grams, Flos Magnoliae 3 grams, Caulis Akebiae 3 grams, Fructus Xanthii 3 grams, Cortex Cinnamomi 2 grams, Herba Asari 3 grams, Bulbus Fritillariae Thunbergii 10 grams, dried Pheretima 10 grams, Rhizoma Atractylodis 2 grams, Semen Raphani 3 grams, Alumen 1 gram, pouring medicine into medicinal cupping uses cold water soak after 25 minutes, changed the slow fire constantly boiling into 20 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 30 minutes after hot water elder generation intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 200 grams.
Embodiment 14
The 200 gram medicinal liquids of obtaining of embodiment 13 are added vaseline 50 grams, glycerol 15 grams, triethanolamine 12 grams, lanoline 6 grams, stearic acid 30 grams and mud pool gold 0.5 gram, be heated to 80 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.
Embodiment 15
Take by weighing Radix Panacis Quinquefolii 10 grams, Cortex Moutan 10 grams, Radix Angelicae Sinensis 10 grams, Retinervus Luffae Fructus 10 grams, Radix Platycodonis 10 grams, Fructus Tribuli 10 grams, Rhizoma Coptidis 10 grams, Radix Astragali 10 grams, Radix Ginseng Rubra 10 grams, Bi  6 grams, Pumex 6 grams, Fructus Forsythiae 6 grams, the Radix Angelicae Dahuricae 3 grams, Flos Magnoliae 3 grams, Caulis Akebiae 3 grams, Fructus Xanthii 3 grams, Cortex Cinnamomi 2 grams, Herba Asari 3 grams, Rhizoma Atractylodis 2 grams, Bulbus Fritillariae Thunbergii 8 grams, pouring medicine into medicinal cupping uses cold water soak after 25 minutes, changed the slow fire constantly boiling into 20 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 30 minutes after hot water elder generation intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 200 grams.
Embodiment 16
The 200 gram medicinal liquids of obtaining of embodiment 15 are added vaseline 50 grams, glycerol 15 grams, triethanolamine 12 grams, lanoline 6 grams, stearic acid 30 grams and mud pool gold 0.5 gram, be heated to 80 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.
Embodiment 17
Take by weighing Radix Panacis Quinquefolii 10 grams, Cortex Moutan 8 grams, Radix Angelicae Sinensis 7 grams, Retinervus Luffae Fructus 6 grams, Radix Platycodonis 5 grams, Fructus Tribuli 6 grams, Rhizoma Coptidis 6 grams, Radix Astragali 8 grams, Radix Ginseng Rubra 6 grams, Bi  7 grams, Pumex 6 grams, Fructus Forsythiae 7 grams, the Radix Angelicae Dahuricae 4 grams, Flos Magnoliae 3 grams, Caulis Akebiae 4 grams, Fructus Xanthii 3 grams, Cortex Cinnamomi 3 grams, Herba Asari 2 grams, Semen Raphani 3 grams, dried Pheretima 10 grams mix, pouring medicine into medicinal cupping uses cold water soak after 30 minutes, changed the slow fire constantly boiling into 30 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 30 minutes after hot water elder generation intense fire is fried boiling, and then medicine juice leached, twice medicine juice merged the medicinal liquids that are concentrated into 300 grams.
Embodiment 18
The 300 gram medicinal liquids of obtaining of embodiment 17 are added vaseline 75 grams, glycerol 22.5 grams, triethanolamine 18 grams, lanoline 9 grams, stearic acid 45 grams and mud pool gold 0.75 gram, be heated to 90 ℃, by the time stop after preparation liquefies fully the heating, be stirred to condensation then, ointment.

Claims (5)

1, a kind of medicine for external use for the treatment of chronic rhinitis, chronic sinusitis is characterized in that including the medicine for external use that the following weight Chinese medicinal raw materials is made:
3~1 parts of 8~5 parts of Pumexs 8 of 10~5 parts of Bi  of 10~5 parts of Radix Ginsengs of 10~5 parts of Radix Astragali of 10~5 portions of Rhizoma Coptidis of 10~5 portions of Fructus Tribulis of 10~5 parts of Radix Platycodoniss of 12~5 parts of Retinervus Luffae Fructuss of 12~5 parts of Radix Angelicae Sinensis of 15~3 parts of Cortex Moutans of Radix Panacis Quinquefolii~3~1 parts of Herba Asaris of 5~1 portions of Cortex Cinnamomis of 5~1 portions of Fructus Xanthii of 5~1 portions of Caulis Akebiaes of 5~1 parts of Flos Magnoliaes of 8~5 parts of Radixs Angelicae Dahuricae of part Fructus Forsythiae.
2, the medicine for external use of treatment chronic rhinitis according to claim 1, chronic sinusitis is characterized in that also containing the medicine for external use that at least 2 kinds of raw material of Chinese medicine of following weight proportioning are made:
3~1 parts of 3~1 parts of Alumens of 3~1 portions of Radix Asteriss of 5~1 parts of coltsfoots of 5~1 parts of Fructus Aurantiis of 5~1 parts of Semen Raphanis of 5~1 parts of Semen Persicaes of 10~5 parts of Rhizoma Atractylodis of 10~5 parts of dried Pheretima of Bulbus Fritillariae Thunbergii, wherein one of Rhizoma Atractylodis or Semen Raphani must contain.
3, the medicine for external use of treatment chronic rhinitis according to claim 1 and 2, chronic sinusitis is characterized in that described medicine for external use is water preparation, tincture, unguentum or cream.
4, the described treatment chronic rhinitis of claim 1, the preparation method of the medicine for external use of chronic sinusitis, it is characterized in that taking by weighing in proportion the Radix Panacis Quinquefolii of formula ratio, Cortex Moutan, Radix Angelicae Sinensis, Retinervus Luffae Fructus, Radix Platycodonis, Fructus Tribuli, Rhizoma Coptidis, Radix Astragali, Radix Ginseng, Bi , Pumex, Fructus Forsythiae, the Radix Angelicae Dahuricae, Flos Magnoliae, Caulis Akebiae, Fructus Xanthii, Cortex Cinnamomi, Herba Asari Chinese medicine, pouring above-mentioned Chinese medicine into medicinal cupping uses cold water soak after 15~30 minutes, changed the slow fire constantly boiling into 20~30 minutes after medicine elder generation intense fire is fried boiling, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 20~30 minutes after the first in the same old way intense fire of hot water is fried boiling, and then medicine juice is leached; Twice medicine juice merged 50%~250% by weight percentage the medicinal liquid that is concentrated into original crude drug amount.
5, the preparation method of the medicine for external use of the described treatment chronic rhinitis of claim 2, chronic sinusitis, it is characterized in that taking by weighing in proportion Radix Panacis Quinquefolii, Cortex Moutan, Radix Angelicae Sinensis, Retinervus Luffae Fructus, Radix Platycodonis, Fructus Tribuli, Rhizoma Coptidis, Radix Astragali, Radix Ginseng, Bi , Pumex, Fructus Forsythiae, the Radix Angelicae Dahuricae, Flos Magnoliae, Caulis Akebiae, Fructus Xanthii, the Cortex Cinnamomi of formula ratio, the Chinese medicine preparation dosage of Herba Asari, take by weighing at least 2 kinds of Chinese medicines in nine kinds of the Bulbus Fritillariae Thunbergiis, dried Pheretima, Rhizoma Atractylodis, Semen Persicae, Semen Raphani, Fructus Aurantii, Flos Farfarae, Radix Asteris, Alumen again, wherein one of Rhizoma Atractylodis or Semen Raphani must contain; Above-mentioned all Chinese medicines that take by weighing are poured into medicinal cupping uses cold water soak after 15~30 minutes, after being fried boiling, elder generation's intense fire changed the slow fire constantly boiling into 20~30 minutes, then medicine juice is leached, medicinal residues add and changed the slow fire constantly boiling into 20~30 minutes after the first in the same old way intense fire of hot water is fried boiling, and then medicine juice is leached; Twice medicine juice merged 50%~250% by weight percentage the medicinal liquid that is concentrated into original crude drug amount.
CNB200610124825XA 2006-10-17 2006-10-17 An external use agent for treating chronic rhinitis and nasosinusitis Expired - Fee Related CN100475250C (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102018857A (en) * 2010-12-02 2011-04-20 袁宗保 Externally applied medicament for treating chronic rhinitis
CN102988812A (en) * 2012-12-20 2013-03-27 孟凡玉 Traditional Chinese medicine composition for treating anaphylactic rhinitis
CN103006986A (en) * 2012-12-21 2013-04-03 西安医学院 Traditional Chinese medicine for treating children cough and preparation method of external use patch thereof
CN105497486A (en) * 2016-01-20 2016-04-20 赵世明 Traditional Chinese medicine composition for treating chronic rhinitis
CN106074725A (en) * 2016-06-27 2016-11-09 农雪梅 A kind of treat the preparation of chronic rhinitis, preparation method and medicine thereof
CN106729553A (en) * 2016-12-28 2017-05-31 张秀兰 It is a kind of to treat medicine of rhinitis chronic and preparation method thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102018857A (en) * 2010-12-02 2011-04-20 袁宗保 Externally applied medicament for treating chronic rhinitis
CN102988812A (en) * 2012-12-20 2013-03-27 孟凡玉 Traditional Chinese medicine composition for treating anaphylactic rhinitis
CN102988812B (en) * 2012-12-20 2014-07-30 孟凡玉 Traditional Chinese medicine composition for treating anaphylactic rhinitis
CN103006986A (en) * 2012-12-21 2013-04-03 西安医学院 Traditional Chinese medicine for treating children cough and preparation method of external use patch thereof
CN103006986B (en) * 2012-12-21 2014-04-02 西安医学院 Traditional Chinese medicine for treating children cough and preparation method of external use patch thereof
CN105497486A (en) * 2016-01-20 2016-04-20 赵世明 Traditional Chinese medicine composition for treating chronic rhinitis
CN106074725A (en) * 2016-06-27 2016-11-09 农雪梅 A kind of treat the preparation of chronic rhinitis, preparation method and medicine thereof
CN106729553A (en) * 2016-12-28 2017-05-31 张秀兰 It is a kind of to treat medicine of rhinitis chronic and preparation method thereof

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