CN1939464A - Chinese-medicinal preparation for treating cold - Google Patents

Chinese-medicinal preparation for treating cold Download PDF

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Publication number
CN1939464A
CN1939464A CN 200610150562 CN200610150562A CN1939464A CN 1939464 A CN1939464 A CN 1939464A CN 200610150562 CN200610150562 CN 200610150562 CN 200610150562 A CN200610150562 A CN 200610150562A CN 1939464 A CN1939464 A CN 1939464A
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chinese medicine
parts
herba
medicine preparation
treatment
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王信锁
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Abstract

A Chinese medicine for treating cold is prepared from 9 Chinese-medicinal material including agastache, honeysuckle flower, tuckahoe, tangerine peel, etc.

Description

A kind of Chinese medicine preparation for the treatment of flu
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of flu, is that a kind of flu for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Flu is that the common exogenous diseases that emits due to the ailment said due to cold or exposure is touched in impression.Clinical manifestation is had a fever with the patient, slight aversion to wind, and turbid tears are flowed in giddy, and are uncomfortable in chest, feel sick, oliguria, it is feature that symptom such as heatstroke is arranged.Cause of disease diseases caused by exogenous pathogenic factor six climate exopathogens, the time row virus, function weakens outside human body is defended, and can not regulate in the strain, from fur, mouth and nose invasion, the evil lung of violating is defended, and defends the table discord and causes a disease.In general, flu seldom has the situation that the change of disease takes place, the short and being easy to recover of the course of disease, but the time sense heavy card, old man, baby children, weak patients, also variable sometimes sick he.Because of primary disease has certain infectiousness, very high at susceptible sickness rate in season, people ' s health and work production are often brought bigger influence, therefore actively control.And at present, one-sidedness is arranged, and side effect is big in the treatment of doctor trained in Western medicine.There is anaphylactoid patient may cause shock to cause death.Utilization Chinese herbal treatment flu is the work of always studying, but present curative effect of medication can not be satisfactory.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of flu, and have determined curative effect, safe ready, little, the cheap characteristics of side effect.
The present invention is made by the following weight proportion raw material:
0.1~4.0 part of 1.5~6.0 portions of Flos Lonicerae of 0.1~2.0 portion of Herba Pogostemonis of Herba Moslae
0.1~4.0 part in 0.1~2.0 part of living Talcum of 1.0~4.0 parts of Poria of Fructus Forsythiae
0.1~2.0 part of 0.1~2.0 part of Pericarpium Citri Reticulatae of 0.1~2.0 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
The weight proportion of each raw material of optimization formula of the present invention is:
1.5~2.5 parts of 2.5~3.5 portions of Flos Loniceraes of 0.5~1.5 portion of Herba Pogostemonis of Herba Moslae
1.5~2.5 parts in 0.5~1.5 part of living Talcum of 1.5~2.5 parts of Poria of Fructus Forsythiae
0.5~1.5 part of 0.5~1.5 part of Pericarpium Citri Reticulatae of 0.5~1.5 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 3 portions of Flos Loniceraes of 1 portion of Herba Pogostemonis of Herba Moslae
2 parts in 1 part of living Talcum of 2 parts of Poria of Fructus Forsythiae
1 part of 1 part of Pericarpium Citri Reticulatae of 1 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
Drug action mechanism among the present invention is as follows:
Herba Moslae nature and flavor suffering, tepor.Attach to the lung and stomach meridians.Has the diaphoresis expelling summer-heat, row water wet dissipation, the effect during stomach warming is transferred.It is cold to treat the moon in summer sense cold fluid-retention, has a headache and fever, and aversion to cold is lossless, feeling of stuffiness in chest stomachache, vomiting and diarrhoea, edema, beriberi etc.(" Chinese medicine voluminous dictionary " the 1681st page).
Herba Pogostemonis nature and flavor suffering, tepor.Return lung, spleen, stomach warp.Have fast gas and in ward off dirty, the effect of damp eliminating.Can treat the flu heat-damp in summer, cold and heat, headache, breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, malaria, dysentery, halitosis etc.(" Chinese medicine voluminous dictionary " the 2710th page).
The Flos Lonicerae nature and flavor are sweet, cold.Return lung, the heart, stomach warp.Has heat-clearing and toxic substances removing, the effect of wind-heat dissipating.Can treat the carbuncle furuncle, scrofula anal fistula, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease heating etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 830th page).
Fructus Forsythiae nature and flavor hardship, be slightly cold.Return lung, the heart, small intestine meridian.Have heat-clearing and toxic substances removing, the knot that disappears looses swollen, and the diuretic effect clears away heart-fire.Can treat carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, hyperpyrexia excessive thirst, coma send out speckle, pyretic stranguria urine retention etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 669th page).
The Poria nature and flavor are sweet, flat, light.GUIXIN, lung, spleen, kidney channel.Has eliminating dampness and diuresis, the effect of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Can treat that dysuria, edema distension, phlegm retention cough with dyspnea, brain are throbbed with fear, have loose bowels in the loose stool, irritability, palpitation with fear, insomnia, forgetful, seminal emission, stranguria with turbid discharge, insufficiency of the spleen, stop that drink is not eaten, gastral cavity is vexed, three YIN malaria (malaria pathogen in three YIN) disease, heating do not heal, end empty YANG-depletion etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 898th page).
It is sweet, light, cold to give birth to the Talcum nature and flavor.Return stomach, urinary bladder channel.Have clearing away heat and promoting diuresis, treating strangurialy quench the thirst, the expelling summer-heat eliminating dampness by diuresis, lead the damp and hot effect of six internal organs.Can treat summer-heat excessive thirst, dysuria, watery diarrhea, hematodiarrhoea, gonorrhea, jaundice, edema, epistaxis, beriberi, Skin wet and rotten, miliaria etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 1196th page).
Herba Artemisiae Annuae nature and flavor hardship, suffering, cold.Return liver, gallbladder meridian.Have heat clearing away, expelling summer-heat, remove the effect of steaming, preventing the attack (or recurrence) of malaria, liver heat removing gallbladder jaundice eliminating.Can treat the pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, disease disease cold and heat, dysentery, jaundice, scabies, pruritus, flaming up of liver-fire, urticaria etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 748th page).
Cortex Magnoliae Officinalis(processed with ginger) nature and flavor suffering, hardship, temperature, fragrance.Return spleen, stomach, lung, large intestine channel.Effect with the analgesia of regulating the flow of vital energy, warming middle-JIAO dampness, eliminating phlegm and relieving asthma.Can treat that breast abdomen feeling of fullness distending pain, humidity hysteresis damaging the spleen and stomach, stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention are breathed with cough, cold-damp dysentery, vomiting, dyspepsia, intestinal obstruction, furuncle and phyma etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 910th page).
Pericarpium Citri Reticulatae nature and flavor hardship, suffering, temperature.Return lung, spleen channel.Has the regulating qi-flowing for strengthening spleen stomach, drying dampness to eliminate phlegm, analgesic effect.Can treat distension and fullness in the abdomen, pain, disorder of stomach-QI, lack of appetite vomiting, the heap soil or fertilizer over and around the roots of cold-damp expectorant, cough with copious phlegm etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 730th page).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Herba Moslae, Herba Pogostemonis, Flos Lonicerae, Fructus Forsythiae, is ministerial drug with Poria, living Talcum, Herba Artemisiae Annuae, is adjuvant with Cortex Magnoliae Officinalis(processed with ginger) and Pericarpium Citri Reticulatae.All medicine phases and the effect that is total to tool heat-clearing and toxic substances removing, diaphoresis expelling summer-heat, the water conservancy of going wets are treated and are caught a cold, and have determined curative effect, have no side effect taking convenience, cheap characteristics.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, buccal tablet, granule, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, preferred Chinese medicine preparation is a peroral dosage form, as: tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment and the preventing cold of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention not only can effectively treat flu, and the prevention of catching a cold is also had good effect, has improved patient's life quality greatly, and higher healing rehabilitation efficacy is arranged.
Further specify the therapeutic effect of medicine of the present invention below by the clinical practice example to the treatment flu.
Summer-heat damp cold curative effect determinate standard (the 60th page of " new Chinese medicine clinical research guideline " Zheng Xiao cornel chief editor Chinese Medicine science and technology publishing house in May, 2002 front page).
1, clinical recovery tcm clinical practice symptom, sign disappear or basic the disappearance; The sign integration reduces 〉=95%.
2, produce effects tcm clinical practice symptom, sign are obviously improved, and the sign integration reduces 〉=70%.
3, effectively tcm clinical practice symptom, sign all take a favorable turn, and the sign integration reduces 〉=30%.
4, invalid tcm clinical practice symptom, sign all do not have obvious improvement, even increase the weight of, the sign integration reduces less than 30%.
As follows through clinical test results; Treatment flu patient 60 examples are taken embodiment 1 capsule, each 2-10 grain, and every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.Three days is a course of treatment, take continuously two the course of treatment observe the curative effect.51 examples of fully recovering account for 85%, and produce effects 4 examples account for 6.67%, and effective 2 examples account for 3.3%, and invalid 3 examples account for 5%, and total effective rate reaches 95%.After two course of therapy, symptoms such as patient's nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, heating etc. all have clear improvement or fully recover.And patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
Embodiment 1 capsule takes by weighing raw material by following weight:
2 parts of 3 portions of Flos Loniceraes of 1 portion of Herba Pogostemonis of Herba Moslae
2 parts in 1 part of living Talcum of 2 parts of Porias of Fructus Forsythiae
1 part of 1 part of Pericarpium Citri Reticulatae of 1 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5~2 hours for the first time, and 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree~55 are concentrated into the clear paste of relative density 1.30~1.32, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, three to four times on the one, three days is a course of treatment.
Embodiment 2 tablets take by weighing raw material by following weight:
2 parts of 3 portions of Flos Loniceraes of 1 portion of Herba Pogostemonis of Herba Moslae
2 parts in 1 part of living Talcum of 2 parts of Porias of Fructus Forsythiae
1 part of 1 part of Pericarpium Citri Reticulatae of 1 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when spending, 50 degree~55 are concentrated into the clear paste of relative density 1.30~1.32, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Usually half an hour ante cibum oral, eliminating cold for resuscitation water send down, one time 2~10, three to four times on the one, three days is a course of treatment.
Embodiment 3 granules take by weighing raw material by following weight:
2 parts of 3 portions of Flos Loniceraes of 1 portion of Herba Pogostemonis of Herba Moslae
2 parts in 1 part of living Talcum of 2 parts of Porias of Fructus Forsythiae
1 part of 1 part of Pericarpium Citri Reticulatae of 1 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
Preparation method is to get above-mentioned raw materials to decoct with water twice, 1.5~2 hours for the first time, and 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, reclaim ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1~3 bag, three to four times on the one, three days is a course of treatment.

Claims (6)

1, a kind of Chinese medicine preparation for the treatment of flu is characterized in that it is made by the following weight proportion raw material:
0.1~4.0 part of 1.5~6.0 portions of Flos Lonicerae of 0.1~2.0 portion of Herba Pogostemonis of Herba Moslae
0.1~4.0 part in 0.1~2.0 part of living Talcum of 1.0~4.0 parts of Poria of Fructus Forsythiae
0.1~2.0 part of 0.1~2.0 part of Pericarpium Citri Reticulatae of 0.1~2.0 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
2, a kind of Chinese medicine preparation for the treatment of flu according to claim 1, wherein the weight proportion of each raw material is:
1.5~2.5 parts of 2.5~3.5 portions of Flos Loniceraes of 0.5~1.5 portion of Herba Pogostemonis of Herba Moslae
1.5~2.5 parts in 0.5~1.5 part of living Talcum of 1.5~2.5 parts of Poria of Fructus Forsythiae
0.5~1.5 part of 0.5~1.5 part of Pericarpium Citri Reticulatae of 0.5~1.5 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
3, a kind of Chinese medicine preparation for the treatment of flu according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 3 portions of Flos Loniceraes of 1 portion of Herba Pogostemonis of Herba Moslae
2 parts in 1 part of living Talcum of 2 parts of Poria of Fructus Forsythiae
1 part of 1 part of Pericarpium Citri Reticulatae of 1 part of Cortex Magnoliae Officinalis(processed with ginger) of Herba Artemisiae Annuae
4, the Chinese medicine preparation of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese medicine preparation of claim 4 is tablet, capsule, oral liquid, buccal tablet, granule, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese medicine preparation of claim 4 is capsule, tablet, granule.
CN 200610150562 2006-10-19 2006-10-19 Chinese-medicinal preparation for treating cold Pending CN1939464A (en)

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Application Number Priority Date Filing Date Title
CN 200610150562 CN1939464A (en) 2006-10-19 2006-10-19 Chinese-medicinal preparation for treating cold

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103800500A (en) * 2014-03-03 2014-05-21 济南伟传信息技术有限公司 Traditional Chinese medicine for treating damp-heat diarrhea

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103800500A (en) * 2014-03-03 2014-05-21 济南伟传信息技术有限公司 Traditional Chinese medicine for treating damp-heat diarrhea
CN103800500B (en) * 2014-03-03 2015-09-16 济南伟传信息技术有限公司 A kind of Chinese medicine for the treatment of damp-heat dysentery

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