CN1919374A - Radiation therapeutical irradiation device - Google Patents

Radiation therapeutical irradiation device Download PDF

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Publication number
CN1919374A
CN1919374A CN 200510036681 CN200510036681A CN1919374A CN 1919374 A CN1919374 A CN 1919374A CN 200510036681 CN200510036681 CN 200510036681 CN 200510036681 A CN200510036681 A CN 200510036681A CN 1919374 A CN1919374 A CN 1919374A
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source
radiation
rotary ring
detector
diagnosis
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CN 200510036681
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CN100591393C (en
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崔智�
黄键
惠小兵
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Haibo Technology Co Ltd Shenzhen
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惠小兵
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Abstract

The invention discloses a radiation device of radiation treatment through rotating focus of gamma ray, which comprises the following parts: rotary ring, source bulk and detector, wherein multiple radiation sources are set in the source bulk, which emits ray to focus on the public focal point on the shaft line of rotary ring, one end of source bulk and detector is connected on the rotary ring, which are distributed symmetrically along radial direction of rotary ring, the high-activity treating radiation source and low-activity diagnosis radiation source are set in the source bulk, the beam of radiation source pierces the shaft line of rotary ring, the detector receives radiation information, which responds to output detecting information.

Description

Radiation device of radiation treatment
Technical field
The present invention relates to a kind of radiating medical equipment, relate in particular to a kind of radiotherapy unit that is used for the gamma ray rotating focus.
Background technology
Using radiotherapy unit to carry out in the radiotherapy; adopt the operation principle of rotating focus that patient's focus is turned round irradiation; make near the lesion tissue of rotation accumulation be subjected to the irradiation of maximal dose; health tissues is subjected to irradiation instantaneous, tolerance dose; thereby kill focus, protect perilesional health tissues, reach radiocurable purpose.The Chinese patent publication number is that the multi-source radiation ray whole body therapeutic apparatus of CN 1275410 discloses a kind of radiotherapy unit, and this device comprises: the source body, with the fixed source of source bulk phase body rotary ring, collimation body, with collimation bulk phase fixed collimation body rotary ring, rotating stand, be fixed on the rotating support ring in the rotating stand.Wherein, between rotating support ring and the source body rotary ring, be respectively equipped with a plurality of rolling bearings between source body rotary ring and the collimation body rotary ring, form being rotatably assorted of axial location.Source body and collimation body can be respectively around same axis of rotation rotations, the a plurality of radioactive sources that distribute in the body of source are by source body and the intravital radiation paths of collimation, focusing is radiated on the public focus of axis of rotation, the collimation body is provided with the collimator in different apertures, the identical collimator in aperture is one group, the regularity of distribution of each group collimator is identical with the regularity of distribution of source body internal source, intravital radioactive source in source and radiation paths radial distribution thereof are in the sector region of an angular range less than 90 degree, axial distribution is in the sector region of an angular range less than 60 degree, and the interior radius of gyration of collimation body is less than the human body width.
The intravital a plurality of radioactive sources in source are treating radiation source in the said apparatus, there is not Real Time Image System, in therapeutic process, can't realize image detects and the monitor therapy target spot moves situation, checking radiotherapy dosage, therefore focusing center and treatment target spot registration accuracy are radiated in influence, can't be according to the actual exposure dose correction therapeutic scheme of patient's reception, can not accomplish precise radiotherapy, influence radiocurable effect.
Summary of the invention
The purpose of this invention is to provide a kind of radiation device of radiation treatment, its technical problem that will solve is that Real Time Image System is provided in radiotherapy, carries out image and detects, and the real-time monitoring and the checking of therapeutic dose, guarantee that radiotherapy is more accurate, improve radiocurable effect.
For achieving the above object the present invention by the following technical solutions: a kind of radiation device of radiation treatment, it comprises: rotary ring, source body, detector, be provided with a plurality of radioactive sources in the body of source, the radiation focus point of the beam-focusing that radioactive source sends on the rotary ring axis, one end of described source body and detector is connected on the rotary ring, and along rotary ring positioned opposite radially; The other end of source body can also be connected on the slip ring.
Be provided with dismountable source casket in the body of source, be provided with treating radiation source and diagnosis radiation source in the casket of source, described diagnosis radiation source is cobalt 60 radioactive sources of a low-activity, be positioned at the central authorities of source body, described treating radiation source is cobalt 60 radioactive sources of the high activity of a plurality of radial alignment arrangements, is distributed on the both sides of diagnosis radiation source.
Described detector is connected on the rotary ring by leverage, and detector can be moved radially along rotary ring, and described rotary ring is provided with external gear.
In the present invention, be provided with the diagnosis radiation source of the treating radiation source and the low-activity of high activity in the body of source, the beam of radioactive source passes the rotary ring axis, inject with the source bulk phase in the detector of arranging, detector responds after receiving the radiation information of diagnosis radiation source, and the output detection information, provide image to detect, realize in the therapeutic process from the movable pendulum position, the real-time monitoring of the situation of treatment target spot motion; Detector responds after receiving the treating radiation source radiation information, and the real-time measurement of exposure dose, the detection information that 3-dimensional dose is rebuild are provided, and realizes the real-time monitoring and the checking of therapeutic dose, guarantees that radiotherapy is more accurate, improves radiocurable effect.
Description of drawings
Fig. 1 is the overall structure sketch map of therapeutic state of the present invention.
Fig. 2 is the cutaway view of Fig. 1.
Fig. 3 is the overall structure sketch map of image formation state of the present invention.
Fig. 4 is the overall structure sketch map of second embodiment of the invention therapeutic state.
Fig. 5 is the cutaway view of Fig. 4.
Fig. 6 is the overall structure cutaway view of third embodiment of the invention therapeutic state.
Fig. 7 is a radiation appliance structural scheme of mechanism of the present invention.
Fig. 8 is the radiation appliance structural scheme of mechanism that the present invention second implements.
Fig. 9 is the structured flowchart of imaging system of the present invention.
1. radiation focus point among the figure, 2. rotation axis, 3. frame, 4. therapeutic bed, 10. source body, 11. treating radiation sources, 12. source body rotary ring, 13. source body connectors, 14. source caskets, 20. the collimation body, 21. collimators, 22. collimation body rotary rings, 23. collimation body connecting pin, 30. diagnosis radiation sourcies, 31. detectors, 32. leverage, 33. preamplifier, 34. data converters, 35. data place devices, 36. gamma knife TPS system, 37. the gamma knife control system, 100. source body drives, 101. source body driving members, 200. the collimation body drive, 201. collimation body driving members.
The specific embodiment
The present invention is further detailed explanation below in conjunction with accompanying drawing embodiment.
As Fig. 1, Fig. 2 and shown in Figure 3, in first embodiment of the present invention, radiotherapy unit comprises: frame 3, be located at the rotary ring 12 on the frame 3,22, the source body 10 and the collimation body 20 that can rotate around rotation axis 2 respectively, be provided with source casket 14 in the source body 10, be loaded with a plurality of radioactive sources in the source casket 14, be provided with many groups and the corresponding collimator 21 of radioactive source in the collimation body, the inner chamber of collimator 21 forms radiation channel, radioactive source focuses on radiation focus point 1 on the rotation axis 2 by radiation channel, one end of source body 10 is fixed on the source body rotary ring 12, the other end is provided with projection or source body connector 13, one end of collimation body 20 is fixed on the collimation body rotary ring 22, the other end is provided with projection or collimation body connector 23, the both sides that are positioned at radiation focus point 1 on the frame 3 are provided with annular groove, the groove of both sides is projection or the source body connector 13 and projection that collimates body 20 1 ends or collimation body connector 23 of reception sources body 10 1 ends respectively, projection can be slidingly matched with the groove in the frame 3, connector 13,23 is uniform a plurality of cylinders, and they can roll with the groove in the frame 3 and cooperate; Source body rotary ring 12 and the both sides that collimate body rotary ring 22 coaxial arrangement radiation focus point 1 on rotation axis 2, its rotation axis 2 overlaps, rotary ring is provided with external gear, external gear on the source body rotary ring 12 is connected with source body drive 100 on being fixed on frame 3 by source body driving member 101, external gear on the collimation body rotary ring 22 is connected by the collimation body drive 200 on collimating body driving member 201 and being fixed on frame 3, be respectively equipped with rolling bearing between source body rotary ring 12 and collimation body rotary ring 22 and the frame 3, form being rotatably assorted of axial location; Therapeutic bed 4 passes source body rotary ring 12 and collimation body rotary ring 22 along rotation axis 2.
The two ends of source of the present invention body 10 and collimation body 20 respectively with rotary ring 12,22, frame 3 connects, this monolayer, the structure of dual-gripper, increased the intra-annular scope of revolution, enlarged the moving range of rotary ring internal therapy bed during treatment, enlarged the treatment space, simplified frame for movement, reduced material, alleviate weight, improved the rigidity of support of source body 10 and collimation body 20, reduced the manufacturing cost and the manufacture difficulty of equipment, manufacturing process is more simple and reliable, assurance source body and collimation body are lasting, stably coaxial rotation makes body 10 internal source beams in source by after collimating the radiation channel in the body 20, and the radioactive source beam-focusing is accurate, guarantee the stability that focusing center's dosage field distributes, and the positional precision of focusing center in therapy system, realize precise radiotherapy, improve radiocurable effect.
Radiotherapy unit also comprises diagnostic imaging system, and this imaging system comprises: diagnosis radiation source 30, detector 31, data handling system; Data handling system comprises: preamplifier 33, data converter 34, data place device 35; Diagnosis radiation source 30 is isotope radioactive sources, also be cobalt 60 radioactive sources of low-activity, diagnosis radiation source 30 is installed in the source casket 14 on the source body 10, and make diagnosis radiation source 31 be in the central authorities of source body 10, detector 31 is connected on the source body rotary ring 12 by leverage 32, diagnosis radiation source 30 in detector 31 and the source body 10 is along rotary ring 12 positioned opposite radially, detector 31 can move to along the beam direction of diagnosis radiation source 30 near the diagnosis position of therapeutic bed 4 or away from the treatment position of therapeutic bed 4, and the driving by source body drive 100, together do stepping rotation or rotation continuously with source body 10 around rotation axis 2; Diagnosis radiation source 30 also can be installed in collimation body 20 central authorities, detector 31 is connected on the collimation body rotary ring 22 by leverage 32 simultaneously, and by collimating the driving of body drive 200, together do stepping rotation or rotation continuously with collimation body 20 around rotation axis 2, diagnosis radiation source 30 in detector 31 and the collimation body 20 is along rotary ring 22 positioned opposite radially, and moves near the diagnosis position of therapeutic bed 4 or away from the treatment position of therapeutic bed 4 along the beam direction of diagnosis radiation source 30 by rotary ring upper lever mechanism 32.
As shown in Figure 7, radiation appliance of the present invention comprises: source body 10, have source body rotary ring 12, the detector 31 of gear; One end of source body 10 is connected on the source body rotary ring 12, and the other end is provided with projection or source body connector 13, and detector 31 is connected on the source body rotary ring 12 by leverage 32, and detector can be moved along the beam direction of diagnosis radiation source 30; Diagnosis radiation source 30 in the source body 10 and detector 31 are along source body rotary ring 12 positioned opposite radially, be provided with dismountable source casket 14 in the source body 10, casket 14 central authorities in source are provided with diagnosis radiation source 30, the treating radiation source 11 of the uniform a plurality of straight line arranged radiallys in diagnosis radiation source 30 both sides, the radiation focus point 1 of the beam-focusing that radioactive source sends on body rotary ring 12 axis of source, and irradiation is on detector 31, detector can receive the beam information of diagnosis radiation source 30 and treating radiation source 11, respond respectively, and output detection information, be fixed on source body drive 100 gear by source body driving member 101 drive source body rotary rings 12 on the support 3, source body rotary ring 12 is rotated around rotation axis 2, simultaneously, driving source body 10 and detector 31 rotates synchronously around rotation axis 2.
As shown in Figure 9, detector 31 both can receive the irradiation of diagnosis radiation source 30, also can receive the irradiation for the treatment of radiation source 11, and respectively information is passed to preamplifier 33 in the data handling system, preamplifier 33 passes to data converter 34 with the irradiation information of amplifying again, export to data place device 35 through after the data transaction, data place device 35 provides associated picture and information according to the information that receives to gamma knife TPS system 36 and gamma knife control system 37; The detector pixel unit is 1mm 2When receiving the irradiation of diagnosis radiation source 30, adopt of the target area imaging of the method for Cone Beam CT to the patient, adopt the method for Radon conversion and filtering back projection, obtain corresponding C T value Density Distribution and fault image, obtain the position coordinates of target area, index point, be used to confirm patient's pendulum position, and the adjustment of pendulum position; When receiving the irradiation for the treatment of radiation source 11, detector array obtains the dose distribution (transmission doses and scattered dose) behind the treating radiation source 11 beam penetration human bodies, utilize the patient CT value Density Distribution of obtaining before the treatment, the method that utilization is deconvoluted, the dosage field of rebuilding patient target area and critical tissue distributes, and this is distributed as the dose distribution of actual irradiation.Because patient target area, body particularly, physiological movement and patient's itself involuntary movement takes place as the target area at positions such as breast, lung, liver, intestinal, kidney, prostate, position in the coordinate of therapeutic equipment in therapeutic process, target area changes, in conjunction with the dose distribution of these change in location information and actual measurement, can estimate the exposure dose and the distribution of the actual acquisition in target area, compare with the planning dosage of TPS, can obtain to revise dosage, be used for patient's additional irradiation.Simultaneously, adopt shortcut calculation, monitor and rebuild fractionated dose (as the dosage of every circle irradiation) in real time, and compare with the fractionated dose figure that plans, provide real-time dosage deviation and dosage correcting scheme, realize the real-time monitoring and the dynamically adjustment of the dose irradiation of gamma knife.
Radiotherapy unit is that gamma ray imaging system and radiotherapy system are integrated integrated, data handling system the is integrated core content of corresponding image, tracking and dosage reconstruction etc., respectively data are handled, form projection scanning, feature point tracking, penetrate data acquisition functions such as dosage measurement, obtain monitoring result and correction data that we wish, realize monitoring in real time, verifying and calibrate.
As Fig. 1 and 2 institute not, when radiotherapy unit is in therapeutic state, collimation body drive 200 drives collimation body rotary ring 22 by collimation body driving member 201 and rotates around rotation axis 2, collimation body 20 rotates an angle with respect to source body 10, make the treating radiation source 11 in one group of collimator, the 21 corresponding source bodies 10 in the collimation body 20 that is fixed on the collimation body rotary ring 22, the radiation channel that beam in the treating radiation source 11 forms by collimator 21 focuses on the radiation focus point 1 on the rotation axis 2, and pass patient on the therapeutic bed 4, irradiation is on detector 31, detector 31 is in treatment position away from therapeutic bed 4 by being connected leverage 32 on the rotary ring 12, driving by source body drive 100 and collimation body drive 200 makes source body 10, collimation body 20, detector 31 together rotates continuously around rotation axis 2.
As shown in Figure 3, when radiotherapy unit is in image formation state, the cylindrical single photon diagnosis radiation source 30 of source body 10 central authorities, a collimator bore passages by collimation body 20 central authorities, pass the patient on the therapeutic bed 4, irradiation is on detector 31, detector 31 is in diagnosis position near therapeutic bed 4 by being connected leverage 32 on the rotary ring 12, by the driving of source body drive 100 and collimation body drive 200, make source body 10, collimation body 20, detector 31 together do stepping and rotate around rotation axis 2.
Shown in Fig. 4,5 and 8, it is the second embodiment of the present invention, one end of source body 10 is fixed on the source body rotary ring 12, the other end is fixed on the source body connector 13, source body connector 13 is for having the cirque structure of concave surface, the outer surface of the internal ring of this concave surface and frame 3 one ends is slidingly matched, and other architectural feature of present embodiment is identical with the architectural feature of the first embodiment of the present invention.
As shown in Figure 6, it is the third embodiment of the present invention, collimation body 20 1 ends are fixed on the collimation body rotary ring 22, the other end is fixed on the collimation body connector 23, collimation body connector 23 is a cirque structure, the internal circular surfaces of the outer surface of this annulus and frame 3 one ends is slidingly matched, and other architectural feature of present embodiment is identical with the architectural feature of the first embodiment of the present invention.

Claims (8)

1. radiation device of radiation treatment, comprise: rotary ring (12), source body (10), detector (31), the source body is provided with a plurality of radioactive sources in (10), the radiation focus point (1) of the beam-focusing that radioactive source sends on rotary ring axis (2), it is characterized in that: an end of described source body (10) and detector (31) is connected on the rotary ring (12), and along rotary ring (12) positioned opposite radially.
2. radiation device of radiation treatment according to claim 1 is characterized in that: be provided with dismountable source casket (14) in the described source body (10), the source casket is provided with radioactive source in (14).
3. radiation device of radiation treatment according to claim 1 is characterized in that: described detector (31) is connected on the rotary ring (12) by leverage, makes the detector (31) can moving radially along rotary ring (12).
4. radiation device of radiation treatment according to claim 1 is characterized in that: described rotary ring (12) is provided with external gear.
5. radiation device of radiation treatment according to claim 1, it is characterized in that: an end of described described source body (10) and detector (31) is connected on the rotary ring (12), and along rotary ring (12) positioned opposite radially, the other end of source body (10) connects on the slip ring.
6. radiation device of radiation treatment according to claim 1 and 2 is characterized in that: be provided with diagnosis radiation source (30) and treating radiation source (11) in the source casket (14) in the described source body (10).
7. radiation device of radiation treatment according to claim 6, it is characterized in that: described diagnosis radiation source (30) is a radioactive source, be positioned at the central authorities of source body (10), described treating radiation source (11) is the radioactive source that a plurality of radial alignment are arranged, and is distributed on the both sides of diagnosis radiation source (30).
8. radiation device of radiation treatment according to claim 6 is characterized in that: described treating radiation source is cobalt 60 radioactive sources of high activity, and described diagnosis radiation source is cobalt 60 radioactive sources of low-activity.
CN200510036681A 2005-08-25 2005-08-25 Radiation therapeutical irradiation device Active CN100591393C (en)

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Cited By (15)

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CN101337113B (en) * 2008-08-27 2010-12-15 广东省职业病防治院 Quality control system and method for radiotherapy device
WO2012055098A1 (en) * 2010-10-27 2012-05-03 玛西普医学科技发展(深圳)有限公司 Radiotherapy apparatus guided by images
CN102549586A (en) * 2009-10-02 2012-07-04 瓦润医药***国际股份公司 Systems and methods for obtaining reconstructed images during a treatment session
CN101088573B (en) * 2006-06-12 2012-07-25 深圳市一体医疗科技股份有限公司 Gamma ray therapeutic equipment
CN102961825A (en) * 2012-12-03 2013-03-13 戴建荣 Method for prolonging service life of external irradiation radioactive source and external irradiation medical equipment
WO2014131179A1 (en) * 2013-02-28 2014-09-04 深圳市奥沃医学新技术发展有限公司 Gamma knife heat treatment apparatus and gamma knife treatment system
CN105833431A (en) * 2016-03-17 2016-08-10 上海联影医疗科技有限公司 Isocenter correction method of radiotherapy equipment
CN106075748A (en) * 2016-07-29 2016-11-09 中国原子能科学研究院 Wobbling magnet diffusion proton beam is utilized to carry out the method and device of oncotherapy
CN106110522A (en) * 2016-07-29 2016-11-16 中国原子能科学研究院 Utilize the method and device of the wobbling magnet diffusion proton beam therapy tumor of variable voltage
WO2017054316A1 (en) * 2015-09-29 2017-04-06 广州瑞多思医疗科技有限公司 Method of online monitoring and verifying dose in radiotherapy
CN106714905A (en) * 2016-08-01 2017-05-24 深圳市奥沃医学新技术发展有限公司 Radiotherapy device and beam imaging method
CN109011207A (en) * 2015-09-28 2018-12-18 南京中硼联康医疗科技有限公司 Beam diagnostic system for neutron capture treatment system
CN111650630A (en) * 2020-05-21 2020-09-11 东华理工大学 Radioactive source arrangement method and system
CN112295118A (en) * 2020-11-11 2021-02-02 陈继红 Cobalt 60 gamma ray radiotherapy device
CN112295117A (en) * 2020-11-11 2021-02-02 陈继红 Cobalt 60 gamma ray radiotherapy device

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EP1060763A3 (en) * 1996-03-26 2001-04-25 Joseph S. Shepherd Radiation therapy and radiation surgery treatment system and methods of use of same
CN1137739C (en) * 1999-05-31 2004-02-11 深圳市海博科技有限公司 Multi-source radioactive ray whole body therapeutic apparatus
CN1133473C (en) * 2000-09-25 2004-01-07 王乔生 Cobalt-60 multi-lamination non-coplanar spiral lamination strength adjustable radiation therapy system

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CN101088573B (en) * 2006-06-12 2012-07-25 深圳市一体医疗科技股份有限公司 Gamma ray therapeutic equipment
CN101337113B (en) * 2008-08-27 2010-12-15 广东省职业病防治院 Quality control system and method for radiotherapy device
CN102549586B (en) * 2009-10-02 2016-02-10 瓦润医药***国际股份公司 For obtaining the system and method rebuilding image during treatment session
CN102549586A (en) * 2009-10-02 2012-07-04 瓦润医药***国际股份公司 Systems and methods for obtaining reconstructed images during a treatment session
WO2012055098A1 (en) * 2010-10-27 2012-05-03 玛西普医学科技发展(深圳)有限公司 Radiotherapy apparatus guided by images
CN102961825A (en) * 2012-12-03 2013-03-13 戴建荣 Method for prolonging service life of external irradiation radioactive source and external irradiation medical equipment
CN104203347A (en) * 2013-02-28 2014-12-10 深圳市奥沃医学新技术发展有限公司 Gamma knife heat treatment apparatus and gamma knife treatment system
WO2014131179A1 (en) * 2013-02-28 2014-09-04 深圳市奥沃医学新技术发展有限公司 Gamma knife heat treatment apparatus and gamma knife treatment system
CN104203347B (en) * 2013-02-28 2017-05-24 深圳市奥沃医学新技术发展有限公司 Gamma knife heat treatment apparatus and gamma knife treatment system
CN109011207A (en) * 2015-09-28 2018-12-18 南京中硼联康医疗科技有限公司 Beam diagnostic system for neutron capture treatment system
WO2017054316A1 (en) * 2015-09-29 2017-04-06 广州瑞多思医疗科技有限公司 Method of online monitoring and verifying dose in radiotherapy
CN105833431A (en) * 2016-03-17 2016-08-10 上海联影医疗科技有限公司 Isocenter correction method of radiotherapy equipment
CN105833431B (en) * 2016-03-17 2018-08-31 上海联影医疗科技有限公司 A kind of bearing calibration of the isocenter point of radiotherapy equipment
CN106075748A (en) * 2016-07-29 2016-11-09 中国原子能科学研究院 Wobbling magnet diffusion proton beam is utilized to carry out the method and device of oncotherapy
CN106110522A (en) * 2016-07-29 2016-11-16 中国原子能科学研究院 Utilize the method and device of the wobbling magnet diffusion proton beam therapy tumor of variable voltage
CN106110522B (en) * 2016-07-29 2018-10-09 中国原子能科学研究院 The device of proton beam therapy tumour is spread using the wobbling magnet of variable voltage
CN106075748B (en) * 2016-07-29 2018-10-09 中国原子能科学研究院 The device of oncotherapy is carried out using wobbling magnet diffusion proton beam
CN106714905A (en) * 2016-08-01 2017-05-24 深圳市奥沃医学新技术发展有限公司 Radiotherapy device and beam imaging method
CN106714905B (en) * 2016-08-01 2019-12-27 深圳市奥沃医学新技术发展有限公司 Radiotherapy equipment and beam imaging method
US11135450B2 (en) 2016-08-01 2021-10-05 Shenzhen Our New Medical Technologies Development Co., Ltd. Radiation therapy apparatus and beam imaging method
CN111650630A (en) * 2020-05-21 2020-09-11 东华理工大学 Radioactive source arrangement method and system
CN111650630B (en) * 2020-05-21 2023-09-01 东华理工大学 Arrangement method and system of radioactive sources
CN112295118A (en) * 2020-11-11 2021-02-02 陈继红 Cobalt 60 gamma ray radiotherapy device
CN112295117A (en) * 2020-11-11 2021-02-02 陈继红 Cobalt 60 gamma ray radiotherapy device

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